Sequence of B4GN1_MOUSE
EC Number:2.4.1.92
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
Q09200
Mus musculus
533
59212
Reaction
UDP-N-acetyl-alpha-D-galactosamine + O-(N-acetyl-alpha-neuraminyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl-(1<->1)-ceramide = UDP + O-2-(acetylamino)-2-deoxy-beta-D-galactopyranosyl-(1->4)-O-[N-acetyl-alpha-neuraminyl-(2->3)]-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl-(1<->1)-ceramide
Other sequences found for EC No. 2.4.1.92
General information:
Sequence
0 MRLDRRALYA LVLLLACASL GLLYSSTRNA PSLPNPLALW SPPQGPPRLD LLDLAPEPRY
60 AHIPVRIKEQ VVGLLAQNNC SCESKGGSLP LPFLRQVRAV DLTKAFDAEE LRAVSVAREQ
120 EYQAFLARSR SLADQLLIAP ANSPLQYPLQ GVEVQPLRSI LVPGLSLQEA SVQEIYQVNL
180 SASLGTWDVA GEVTGVTLTG EGQPDLTLAS PVLDKLNRQL QLVTYSSRSY QANTADTVRF
240 STKGHEVAFT ILVRHPPNPR LYPPSSLPQG AEYNISALVT IATKTFLRYD RLRTLIASIR
300 RFYPTVTIVI ADDSDKPERI SDPHVEHYFM PFGKGWFAGR NLAVSQVTTK YVLWVDDDFV
360 FTARTRLEKL VDVLEKTPLD LVGGAVREIS GYATTYRQLL SVEPGAPGLG NCFRQKQGFH
420 HELVGFPSCV VTDGVVNFFL ARTDKVRQVG FDPRLNRVAH LEFFLDGLGF LRVGSCSDVV
480 VDHASKVKLP WTAKDPGAET YARYRYPGSL DQSQVAKHRL LFFKHRLQCM TAE
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
9579
Takamiya K.,Yamamoto A.,Yamashiro S.,Furukawa K.,Haraguchi M.,Okada M.,Ikeda T.,Shiku H.,Furukawa K.
T cell receptor-mediated stimulation of mouse thymocytes induces up-regulation of the GM2/GD2 synthase gene.
FEBS Lett.
358
79-83
1995
9580
Sango K.,Johnson O.N.,Kozak C.A.,Proia R.L.
Beta-1,4-N-acetylgalactosaminyltransferase involved in ganglioside synthesis: cDNA sequence, expression, and chromosome mapping of the mouse gene.
Genomics
27
362-365
1995
9581
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
9582
Takamiya K.,Yamamoto A.,Furukawa K.,Yamashiro S.,Shin M.,Okada M.,Fukumoto S.,Haraguchi M.,Takeda N.,Fujimura K.,Sakae M.,Kishikawa M.,Shiku H.,Furukawa K.,Aizawa S.
Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system.
Proc. Natl. Acad. Sci. U.S.A.
93
10662-10667
1996
9583
Pan B.,Fromholt S.E.,Hess E.J.,Crawford T.O.,Griffin J.W.,Sheikh K.A.,Schnaar R.L.
Myelin-associated glycoprotein and complementary axonal ligands, gangliosides, mediate axon stability in the CNS and PNS: neuropathology and behavioral deficits in single- and double-null mice.
Exp. Neurol.
195
208-217
2005
9584
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
9585
Peng L.,Tepp W.H.,Johnson E.A.,Dong M.
Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors.
PLoS Pathog.
7
0-0
2011
