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Sequence of CHS2_MEDSA

EC Number:2.3.1.74

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
chalcone synthase
P30074
Medicago sativa
389
42706
Reaction
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2
Other sequences found for EC No. 2.3.1.74

General information:

Sequence
show sequence in fasta format
  0 MVSVSEIRKA QRAEGPATIL AIGTANPANC VEQSTYPDFY FKITNSEHKT ELKEKFQRMC
 60 DKSMIKRRYM YLTEEILKEN PNVCEYMAPS LDARQDMVVV EVPRLGKEAA VKAIKEWGQP
120 KSKITHLIVC TTSGVDMPGA DYQLTKLLGL RPYVKRYMMY QQGCFAGGTV LRLAKDLAEN
180 NKGARVLVVC SEVTAVTFRG PSDTHLDSLV GQALFGDGAA ALIVGSDPVP EIEKPIFEMV
240 WTAQTIAPDS EGAIDGHLRE AGLTFHLLKD VPGIVSKNIT KALVEAFEPL GISDYNSIFW
300 IAHPGGPAIL DQVEQKLALK PEKMNATREV LSEYGNMSSA CVLFILDEMR KKSTQNGLKT
360 TGEGLEWGVL FGFGPGLTIE TVVLRSVAI
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
17104
Junghans H.,Dalkin K.,Dixon R.A.
Stress responses in alfalfa (Medicago sativa L.). 15. Characterization and expression patterns of members of a subset of the chalcone synthase multigene family.
Plant Mol. Biol.
22
239-253
1993
17105
Ferrer J.L.,Jez J.M.,Bowman M.E.,Dixon R.A.,Noel J.P.
Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis.
Nat. Struct. Biol.
6
775-784
1999
17106
Jez J.M.,Ferrer J.L.,Bowman M.E.,Dixon R.A.,Noel J.P.
Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase.
Biochemistry
39
890-902
2000
17107
Jez J.M.,Bowman M.E.,Noel J.P.
Structure-guided programming of polyketide chain-length determination in chalcone synthase.
Biochemistry
40
14829-14838
2001
17108
Jez J.M.,Bowman M.E.,Noel J.P.
Expanding the biosynthetic repertoire of plant type III polyketide synthases by altering starter molecule specificity.
Proc. Natl. Acad. Sci. U.S.A.
99
5319-5324
2002
17109
Austin M.B.,Bowman M.E.,Ferrer J.-L.,Schroeder J.,Noel J.P.
An aldol switch discovered in stilbene synthases mediates cyclization specificity of type III polyketide synthases.
Chem. Biol.
11
1179-1194
2004