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Sequence of PSB8_MOUSE

EC Number:3.4.25.1

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
proteasome endopeptidase complex
P28063
Mus musculus
276
30260
Reaction
cleavage of peptide bonds with very broad specificity
Other sequences found for EC No. 3.4.25.1

General information:

Sequence
show sequence in fasta format
  0 MALLDLCGAA RGQRPEWAAL DAGSGGRSDP GHYSFSAQAP ELALPRGMQP TAFLRSFGGD
 60 QERNVQIEMA HGTTTLAFKF QHGVIVAVDS RATAGSYISS LRMNKVIEIN PYLLGTMSGC
120 AADCQYWERL LAKECRLYYL RNGERISVSA ASKLLSNMML QYRGMGLSMG SMICGWDKKG
180 PGLYYVDDNG TRLSGQMFST GSGNTYAYGV MDSGYRQDLS PEEAYDLGRR AIAYATHRDN
240 YSGGVVNMYH MKEDGWVKVE SSDVSDLLYK YGEAAL
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
210104
Frentzel S.,Graef U.,Haemmerling G.,Kloetzel P.-M.
Isolation and characterization of the MHC linked beta-type proteasome subunit MC13 cDNA.
FEBS Lett.
302
121-125
1992
210105
Meinhardt T.,Graf U.,Hammerling G.J.
Different genomic structure of mouse and human Lmp7 genes: characterization of MHC-encoded proteasome genes.
Immunogenetics
38
373-379
1993
210106
Zanelli E.H.,Zhou P.,Hong C.,Smart M.K.,David C.S.
Genomic organization and tissue expression of the mouse proteasome gene Lmp-7.
Immunogenetics
38
400-407
1993
210107
Nandi D.,Iyer M.N.,Monaco J.J.
Molecular and serological analysis of polymorphisms in the murine major histocompatibility complex-encoded proteasome subunits, LMP-2 and LMP-7.
Exp. Clin. Immunogenet.
13
20-29
1996
210108
Carninci P.,Kasukawa T.,Katayama S.,Gough J.,Frith M.C.,Maeda N.,Oyama R.,Ravasi T.,Lenhard B.,Wells C.,Kodzius R.,Shimokawa K.,Bajic V.B.,Brenner S.E.,Batalov S.,Forrest A.R.,Zavolan M.,Davis M.J.,Wilming L.G.,Aidinis V.,Allen J.E.,Ambesi-Impiombato A.,Apweiler R.,Aturaliya R.N.,Bailey T.L.,Bansal M.,Baxter L.,Beisel K.W.,Bersano T.,Bono H.,Chalk A.M.,Chiu K.P.,Choudhary V.,Christoffels A.,Clutterbuck D.R.,Crowe M.L.,Dalla E.,Dalrymple B.P.,de Bono B.,Della Gatta G.,di Bernardo D.,Down T.,Engstrom P.,Fagiolini M.,Faulkner G.,Fletcher C.F.,Fukushima T.,Furuno M.,Futaki S.,Gariboldi M.,Georgii-Hemming P.,Gingeras T.R.,Gojobori T.,Green R.E.,Gustincich S.,Harbers M.,Hayashi Y.,Hensch T.K.,Hirokawa N.,Hill D.,Huminiecki L.,Iacono M.,Ikeo K.,Iwama A.,Ishikawa T.,Jakt M.,Kanapin A.,Katoh M.,Kawasawa Y.,Kelso J.,Kitamura H.,Kitano H.,Kollias G.,Krishnan S.P.,Kruger A.,Kummerfeld S.K.,Kurochkin I.V.,Lareau L.F.,Lazarevic D.,Lipovich L.,Liu J.,Liuni S.,McWilliam S.,Madan Babu M.,Madera M.,Marchionni L.,Matsuda H.,Matsuzawa S.,Miki H.,Mignone F.,Miyake S.,Morris K.,Mottagui-Tabar S.,Mulder N.,Nakano N.,Nakauchi H.,Ng P.,Nilsson R.,Nishiguchi S.,Nishikawa S.,Nori F.,Ohara O.,Okazaki Y.,Orlando V.,Pang K.C.,Pavan W.J.,Pavesi G.,Pesole G.,Petrovsky N.,Piazza S.,Reed J.,Reid J.F.,Ring B.Z.,Ringwald M.,Rost B.,Ruan Y.,Salzberg S.L.,Sandelin A.,Schneider C.,Schoenbach C.,Sekiguchi K.,Semple C.A.,Seno S.,Sessa L.,Sheng Y.,Shibata Y.,Shimada H.,Shimada K.,Silva D.,Sinclair B.,Sperling S.,Stupka E.,Sugiura K.,Sultana R.,Takenaka Y.,Taki K.,Tammoja K.,Tan S.L.,Tang S.,Taylor M.S.,Tegner J.,Teichmann S.A.,Ueda H.R.,van Nimwegen E.,Verardo R.,Wei C.L.,Yagi K.,Yamanishi H.,Zabarovsky E.,Zhu S.,Zimmer A.,Hide W.,Bult C.,Grimmond S.M.,Teasdale R.D.,Liu E.T.,Brusic V.,Quackenbush J.,Wahlestedt C.,Mattick J.S.,Hume D.A.,Kai C.,Sasaki D.,Tomaru Y.,Fukuda S.,Kanamori-Katayama M.,Suzuki M.,Aoki J.,Arakawa T.,Iida J.,Imamura K.,Itoh M.,Kato T.,Kawaji H.,Kawagashira N.,Kawashima T.,Kojima M.,Kondo S.,Konno H.,Nakano K.,Ninomiya N.,Nishio T.,Okada M.,Plessy C.,Shibata K.,Shiraki T.,Suzuki S.,Tagami M.,Waki K.,Watahiki A.,Okamura-Oho Y.,Suzuki H.,Kawai J.,Hayashizaki Y.
The transcriptional landscape of the mammalian genome.
Science
309
1559-1563
2005
210110
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
210111
Fehling H.J.,Swat W.,Laplace C.,Kuehn R.,Rajewsky K.,Mueller U.,von Boehmer H.
MHC class I expression in mice lacking the proteasome subunit LMP-7.
Science
265
1234-1237
1994
210112
Kinser S.,Jia Q.,Li M.,Laughter A.,Cornwell P.,Corton J.C.,Pestka J.
Gene expression profiling in spleens of deoxynivalenol-exposed mice: immediate early genes as primary targets.
J. Toxicol. Environ. Health Part A
67
1423-1441
2004
210113
Namiki S.,Nakamura T.,Oshima S.,Yamazaki M.,Sekine Y.,Tsuchiya K.,Okamoto R.,Kanai T.,Watanabe M.
IRF-1 mediates upregulation of LMP7 by IFN-gamma and concerted expression of immunosubunits of the proteasome.
FEBS Lett.
579
2781-2787
2005
210114
Callahan M.K.,Wohlfert E.A.,Menoret A.,Srivastava P.K.
Heat shock up-regulates lmp2 and lmp7 and enhances presentation of immunoproteasome-dependent epitopes.
J. Immunol.
177
8393-8399
2006
210115
James A.B.,Conway A.M.,Morris B.J.
Regulation of the neuronal proteasome by Zif268 (Egr1).
J. Neurosci.
26
1624-1634
2006
210116
Gomes A.V.,Zong C.,Edmondson R.D.,Li X.,Stefani E.,Zhang J.,Jones R.C.,Thyparambil S.,Wang G.W.,Qiao X.,Bardag-Gorce F.,Ping P.
Mapping the murine cardiac 26S proteasome complexes.
Circ. Res.
99
362-371
2006
210117
Muchamuel T.,Basler M.,Aujay M.A.,Suzuki E.,Kalim K.W.,Lauer C.,Sylvain C.,Ring E.R.,Shields J.,Jiang J.,Shwonek P.,Parlati F.,Demo S.D.,Bennett M.K.,Kirk C.J.,Groettrup M.
A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis.
Nat. Med.
15
781-787
2009
210118
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
210119
Kitamura A.,Maekawa Y.,Uehara H.,Izumi K.,Kawachi I.,Nishizawa M.,Toyoshima Y.,Takahashi H.,Standley D.M.,Tanaka K.,Hamazaki J.,Murata S.,Obara K.,Toyoshima I.,Yasutomo K.
A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans.
J. Clin. Invest.
121
4150-4160
2011
210120
Qian M.X.,Pang Y.,Liu C.H.,Haratake K.,Du B.Y.,Ji D.Y.,Wang G.F.,Zhu Q.Q.,Song W.,Yu Y.,Zhang X.X.,Huang H.T.,Miao S.,Chen L.B.,Zhang Z.H.,Liang Y.N.,Liu S.,Cha H.,Yang D.,Zhai Y.,Komatsu T.,Tsuruta F.,Li H.,Cao C.,Li W.,Li G.H.,Cheng Y.,Chiba T.,Wang L.,Goldberg A.L.,Shen Y.,Qiu X.B.
Acetylation-mediated proteasomal degradation of core histones during DNA repair and spermatogenesis.
Cell
153
1012-1024
2013
210121
Huber E.M.,Basler M.,Schwab R.,Heinemeyer W.,Kirk C.J.,Groettrup M.,Groll M.
Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity.
Cell
148
727-738
2012