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Sequence of ERG7_YEAST

EC Number:5.4.99.7

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Lanosterol synthase
P38604
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
731
83460
Reaction
(3S)-2,3-epoxy-2,3-dihydrosqualene = lanosterol
Other sequences found for EC No. 5.4.99.7

General information:

Sequence
show sequence in fasta format
  0 MTEFYSDTIG LPKTDPRLWR LRTDELGRES WEYLTPQQAA NDPPSTFTQW LLQDPKFPQP
 60 HPERNKHSPD FSAFDACHNG ASFFKLLQEP DSGIFPCQYK GPMFMTIGYV AVNYIAGIEI
120 PEHERIELIR YIVNTAHPVD GGWGLHSVDK STVFGTVLNY VILRLLGLPK DHPVCAKARS
180 TLLRLGGAIG SPHWGKIWLS ALNLYKWEGV NPAPPETWLL PYSLPMHPGR WWVHTRGVYI
240 PVSYLSLVKF SCPMTPLLEE LRNEIYTKPF DKINFSKNRN TVCGVDLYYP HSTTLNIANS
300 LVVFYEKYLR NRFIYSLSKK KVYDLIKTEL QNTDSLCIAP VNQAFCALVT LIEEGVDSEA
360 FQRLQYRFKD ALFHGPQGMT IMGTNGVQTW DCAFAIQYFF VAGLAERPEF YNTIVSAYKF
420 LCHAQFDTEC VPGSYRDKRK GAWGFSTKTQ GYTVADCTAE AIKAIIMVKN SPVFSEVHHM
480 ISSERLFEGI DVLLNLQNIG SFEYGSFATY EKIKAPLAME TLNPAEVFGN IMVEYPYVEC
540 TDSSVLGLTY FHKYFDYRKE EIRTRIRIAI EFIKKSQLPD GSWYGSWGIC FTYAGMFALE
600 ALHTVGETYE NSSTVRKGCD FLVSKQMKDG GWGESMKSSE LHSYVDSEKS LVVQTAWALI
660 ALLFAEYPNK EVIDRGIDLL KNRQEESGEW KFESVEGVFN HSCAIEYPSY RFLFPIKALG
720 MYSRAYETHT L
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
31037
Corey E.J.,Matsuda S.P.T.,Bartel B.
Molecular cloning, characterization, and overexpression of ERG7, the Saccharomyces cerevisiae gene encoding lanosterol synthase.
Proc. Natl. Acad. Sci. U.S.A.
91
2211-2215
1994
31038
Shi Z.,Buntel C.J.,Griffin J.H.
Isolation and characterization of the gene encoding 2,3-oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae.
Proc. Natl. Acad. Sci. U.S.A.
91
7370-7374
1994
31040
Johnston M.,Andrews S.,Brinkman R.,Cooper J.,Ding H.,Dover J.,Du Z.,Favello A.,Fulton L.,Gattung S.,Geisel C.,Kirsten J.,Kucaba T.,Hillier L.W.,Jier M.,Johnston L.,Langston Y.,Latreille P.,Louis E.J.,Macri C.,Mardis E.,Menezes S.,Mouser L.,Nhan M.,Rifkin L.,Riles L.,St Peter H.,Trevaskis E.,Vaughan K.,Vignati D.,Wilcox L.,Wohldman P.,Waterston R.,Wilson R.,Vaudin M.
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.
Science
265
2077-2082
1994
31041
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
31042
Hu Y.,Rolfs A.,Bhullar B.,Murthy T.V.S.,Zhu C.,Berger M.F.,Camargo A.A.,Kelley F.,McCarron S.,Jepson D.,Richardson A.,Raphael J.,Moreira D.,Taycher E.,Zuo D.,Mohr S.,Kane M.F.,Williamson J.,Simpson A.J.G.,Bulyk M.L.,Harlow E.,Marsischky G.,Kolodner R.D.,LaBaer J.
Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
Genome Res.
17
536-543
2007
31044
Balliano G.,Viola F.,Ceruti M.,Cattel L.
Characterization and partial purification of squalene-2,3-oxide cyclase from Saccharomyces cerevisiae.
Arch. Biochem. Biophys.
293
122-129
1992
31045
Milla P.,Athenstaedt K.,Viola F.,Oliaro-Bosso S.,Kohlwein S.D.,Daum G.,Balliano G.
Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles.
J. Biol. Chem.
277
2406-2412
2002
31046
Mo C.,Milla P.,Athenstaedt K.,Ott R.,Balliano G.,Daum G.,Bard M.
In yeast sterol biosynthesis the 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity.
Biochim. Biophys. Acta
1633
68-74
2003
31047
Huh W.-K.,Falvo J.V.,Gerke L.C.,Carroll A.S.,Howson R.W.,Weissman J.S.,O'Shea E.K.
Global analysis of protein localization in budding yeast.
Nature
425
686-691
2003
31048
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
31049
Oliaro-Bosso S.,Schulz-Gasch T.,Balliano G.,Viola F.
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach.
ChemBioChem
6
2221-2228
2005
31050
Van Damme P.,Lasa M.,Polevoda B.,Gazquez C.,Elosegui-Artola A.,Kim D.S.,De Juan-Pardo E.,Demeyer K.,Hole K.,Larrea E.,Timmerman E.,Prieto J.,Arnesen T.,Sherman F.,Gevaert K.,Aldabe R.
N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
Proc. Natl. Acad. Sci. U.S.A.
109
12449-12454
2012
31051
Jorda T.,Puig S.
Regulation of ergosterol biosynthesis in Saccharomyces cerevisiae.
Genes (Basel)
11
0-0
2020