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Sequence of RAC3_HUMAN

EC Number:3.6.5.2

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
small monomeric GTPase
P60763
Homo sapiens
192
21379
Reaction
GTP + H2O = GDP + phosphate
Other sequences found for EC No. 3.6.5.2

General information:

Sequence
show sequence in fasta format
  0 MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGKP VNLGLWDTAG
 60 QEDYDRLRPL SYPQTDVFLI CFSLVSPASF ENVRAKWYPE VRHHCPHTPI LLVGTKLDLR
120 DDKDTIERLR DKKLAPITYP QGLAMAREIG SVKYLECSAL TQRGLKTVFD EAIRAVLCPP
180 PVKKPGKKCT VF
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
342040
Haataja L.,Groffen J.,Heisterkamp N.
Characterization of RAC3, a novel member of the Rho family.
J. Biol. Chem.
272
20384-20388
1997
342043
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
342044
Haataja L.,Groffen J.,Heisterkamp N.
Identification of a novel Rac3-interacting protein C1D.
Int. J. Mol. Med.
1
665-670
1998
342045
De Langhe S.,Haataja L.,Senadheera D.,Groffen J.,Heisterkamp N.
Interaction of the small GTPase Rac3 with NRBP, a protein with a kinase-homology domain.
Int. J. Mol. Med.
9
451-459
2002
342046
Haataja L.,Kaartinen V.,Groffen J.,Heisterkamp N.
The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and spreading.
J. Biol. Chem.
277
8321-8328
2002
342047
Watabe-Uchida M.,John K.A.,Janas J.A.,Newey S.E.,Van Aelst L.
The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18.
Neuron
51
727-739
2006
342048
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
342049
Jank T.,Bogdanovic X.,Wirth C.,Haaf E.,Spoerner M.,Boehmer K.E.,Steinemann M.,Orth J.H.,Kalbitzer H.R.,Warscheid B.,Hunte C.,Aktories K.
A bacterial toxin catalyzing tyrosine glycosylation of Rho and deamidation of Gq and Gi proteins.
Nat. Struct. Mol. Biol.
20
1273-1280
2013
342050
White J.J.,Mazzeu J.F.,Coban-Akdemir Z.,Bayram Y.,Bahrambeigi V.,Hoischen A.,van Bon B.W.M.,Gezdirici A.,Gulec E.Y.,Ramond F.,Touraine R.,Thevenon J.,Shinawi M.,Beaver E.,Heeley J.,Hoover-Fong J.,Durmaz C.D.,Karabulut H.G.,Marzioglu-Ozdemir E.,Cayir A.,Duz M.B.,Seven M.,Price S.,Ferreira B.M.,Vianna-Morgante A.M.,Ellard S.,Parrish A.,Stals K.,Flores-Daboub J.,Jhangiani S.N.,Gibbs R.A.,Brunner H.G.,Sutton V.R.,Lupski J.R.,Carvalho C.M.B.
WNT signaling perturbations underlie the genetic heterogeneity of Robinow syndrome.
Am. J. Hum. Genet.
102
27-43
2018
342051
Costain G.,Callewaert B.,Gabriel H.,Tan T.Y.,Walker S.,Christodoulou J.,Lazar T.,Menten B.,Orkin J.,Sadedin S.,Snell M.,Vanlander A.,Vergult S.,White S.M.,Scherer S.W.,Hayeems R.Z.,Blaser S.,Wodak S.J.,Chitayat D.,Marshall C.R.,Meyn M.S.
De novo missense variants in RAC3 cause a novel neurodevelopmental syndrome.
Genet. Med.
21
1021-1026
2019