Sequence of UBP2_KLULA
EC Number:3.4.19.12
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
ubiquitinyl hydrolase 1
O42726
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
1220
141120
Reaction
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)
Other sequences found for EC No. 3.4.19.12
General information:
Sequence
0 MMASQEPALE LNGEQRDSVS ETAEVLRSKS LESFSDLVDD GKTLLYGDIS KSFPFKTCDR
60 ILDDIRISPW FLKKFGSSVM KQPMLQYSRE RQQLQPWNLV HLIDQVNLRS RYDYDSMTCP
120 GKNTISVMFA LLVDPNFTPN DFDDIDKFPE YFFHLKITVK RRSYLENFNR HVGITHYHVL
180 EPESLHPFDK RDIFIMEEKD CRLVDQSIFV SADTNKLILV EIIKPEFNSE NLAEYRTAKI
240 EERYKNACQE FDLLNPDDIP SQAECLKTLF MIFKNPLQRK SANSEFKIIS RDSVALNSQI
300 NTDWLTTMFD FSLQKTAVED NVQSGEEYKP PDLVDYITDF KVRGIREAYT RKSMEVVLIG
360 KQSMLLENEL GTEKKTVAKC FSNQHFSASH TWWFNILNHQ HIEPFPYDIN YHFINLSVAF
420 KYIDKDIIKN YETQIALDQE NISHYFDALQ YVTNAKGSYQ LIAYCGKQDV VGYEDLNNAL
480 QVFGLDPTDI DASLLDANTM IEYYNSHLLR SSDNQRKDLR NALRVLGKYL GSQKMLFLVE
540 YEPYYNVQQA YTLLKVDETV DDDIIQTAYT INIADAPGLK KDYDRAIFTI ALDRRSIFLL
600 NVLTDECPEF AQYYNCTDIS YDEALNIIEI DMNASDDVIL EVFQKKWSHG IMTGPDYLLK
660 LKMALQNIGF TRNSKLINHF LDTGIVDVSC LPVATWPAGI NNVGNTCYLN SLLQFFFTIK
720 PLRDFILNYD DDSAKLLDAS EYHSRRRIGG REVSKQEELR SVQFVYHLRD LFNDMIHTNS
780 RCVTPTKELV YLAFAPSNVE VEFGDDTVAQ KELIDLTTDV VEDPTDTTRH LASCDDDIIM
840 CQSPVALPEH KTSSEAGTQQ YSVQVAKISA DQLENTLEIG RQQDVTECIG NVLAQLEIAS
900 EPLSLEDDLE QNDLVKQLFY GRIKQDLIPV NDEASVRTKY ERFLSLLVNT GDHPKDIYDA
960 LDFYFQNDYL NLEEYGDVKR TVSISELPAV LQIQIQRVYY DREKFMPFKS IEPLPFGETL
1020 YMDRYMATED PKLLAEIQQN AELKQKLQDL KQRQRKLLSQ NEIGLTLKSS LIETKKFLQS
1080 GTLKAHDIDA DNIPSSIAYI DILINNIDEE LKSLFNKITD LETTISQQFS EFKHIGYSLF
1140 AVFIHRGEAS YGHYWVYIKD HTKNGIWRKY NDDSVTEVPQ SEVFNFTEGN TATPYFLVYV
1200 REGQEQETIE PLKRILQQQE
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
497678
Winkler A.A.,Korstanje R.,Zonneveld B.J.M.,Hooykaas P.J.J.,Steensma H.Y.
Isolation and characterization of KIUBP2, a ubiquitin hydrolase gene of Kluyveromyces lactis that can suppress a ts-mutation in CBF2, a gene encoding a centromeric protein of Saccharomyces cerevisiae.
Curr. Genet.
38
17-22
2000
497679
Dujon B.,Sherman D.,Fischer G.,Durrens P.,Casaregola S.,Lafontaine I.,de Montigny J.,Marck C.,Neuveglise C.,Talla E.,Goffard N.,Frangeul L.,Aigle M.,Anthouard V.,Babour A.,Barbe V.,Barnay S.,Blanchin S.,Beckerich J.-M.,Beyne E.,Bleykasten C.,Boisrame A.,Boyer J.,Cattolico L.,Confanioleri F.,de Daruvar A.,Despons L.,Fabre E.,Fairhead C.,Ferry-Dumazet H.,Groppi A.,Hantraye F.,Hennequin C.,Jauniaux N.,Joyet P.,Kachouri R.,Kerrest A.,Koszul R.,Lemaire M.,Lesur I.,Ma L.,Muller H.,Nicaud J.-M.,Nikolski M.,Oztas S.,Ozier-Kalogeropoulos O.,Pellenz S.,Potier S.,Richard G.-F.,Straub M.-L.,Suleau A.,Swennen D.,Tekaia F.,Wesolowski-Louvel M.,Westhof E.,Wirth B.,Zeniou-Meyer M.,Zivanovic Y.,Bolotin-Fukuhara M.,Thierry A.,Bouchier C.,Caudron B.,Scarpelli C.,Gaillardin C.,Weissenbach J.,Wincker P.,Souciet J.-L.
Genome evolution in yeasts.
Nature
430
35-44
2004
