>Q5RAY1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pongo abelii|Swiss-Prot
MAQISSNSGFKECPSSHPEPTRAKDVDKEEALQMEAEALAKLQKDRQVTDNQRGFELSSS
TRKKAQVYNKQDYDLMVFPESDSQKRALDIDVEKLTQAELEKLLLDDSLETRKTPVLPVT
PILSPSFSAQLYFRPTIQRGQWPPGLSGPSTYALPSIYPSTYSKQAAFQNGFNPRMPTFP
STEPIYLSLPGQSPYFSYPLTPATPFHPQGSLPIYRPVVSPDMAKLFDKIASTSEFLKNG
KARADLEITDSKVSNLQVSPKSEDISKFDWLDLDPLSKPKVDNVEVLDHEEEKNVSSLLA
KDPWDAVLLEERSTANCHLERKMNGKSLSVATVTRSQSLNIRTTQLAKAHISQKDPNGTS
SLPTGSSLLQEVEVQNEEMAAFSRSITKLKTKFPYTNHHTNPGYLLSPVTAQRNICGENA
SVKVSIDIEGFQLPVTFTCDVSSTVEIIIMQALCWVHDDLNQVDVGSYVLKVCGQEEVLQ
NNHCLGSHEHIQNCRKWDTEIRLQLLTFSAMCQNLARTAEDDETPVDLNKHLYQIEKPYK
EAMTRHPVEELLDSYHNQVELALQIENQHRAVDQVIKAVRKICSALDGVETLAITESVKK
LKRAVNLPRSKTADVASLFGGEDTSKSSTRGSLNPENPVQVSINQLTAAIYDLLRLHANS
GRSPTDCAQSSKSVKEAWTTTEQLQFTIFAAHGISSNWVSNYEKYYLICSLSHNGKDLFK
PIQSKKVGTYKNFFYLIKWDELIIFPIQISQLPLESLLHLTLFGILNQSSGSSPDSNKQR
KGPEALGKVSLPLFDFKRFLTCGTKLLYLWTSSHTNSVPGAVTKKGYVMERIVLQVDFPS
PAFDIIYTTPQVDRSIIQQHNLETLENDVKGKLLDILHKDSSLGLSKEDKAFLWEKRYYC
FKHPNCLPKILASAPNWKWVNLAKTYSLLHQWPALYPLIALELLDSKFADQEVRSLAVTW
IEAISDDELTDLLPQFVQALKYEIYLNSSLVQFLLSRALGNIQIAHNLYWLLKDALHDVQ
FSTRYEHVLGALLSVGGKRLREELRKQTKLVQLLGGVAEKVRQASGSARQVVLQRSMERV
QSFFQKNKCRLPLKPSLVAKELSIKSCSFFSSNAVPLKVTMVNADPMGEEINVMFKVGED
LRQDMLALQMIKIMDKIWLKEGLDLRMVIFKCLSTGRDRGMVELVPASDTLRKIQVEYGV
TGSFKDKPLAEWLRKYNPSEEEYEKASENFIYSCAGCCVATYVLGICDRHNDNIMLRSTG
HMFHIDFGKFLGHAQMFGTFKRDRAPFVLTSDMAYVINGGEKPTIRFQLFVDLCCQAYNL
IRKQTNLFLNLLSLMIPSGLPELTSIQDLKYVRDALQPQTTDAEATIFFTRLIESSLGSI
ATKFNFLIHNLAQLRFSGLPSNDEPILSFSPKTYSFKQDGRIKEVSVFTYHKKYNPDKHY
IYVVRILREGQIEPSFVFRTFDEFQELHNKLSIIFPLWKLPGFPNRMVLGRTHIKDVAAK
RKIELNSYLQSLMNASTDVAECDLVCTFFHPLLRDEKAEGIARSADAGSFSPPTPGQIGG
AVKLSISYRNGTLFIMVMHTKDLVTEDGADPNPYVKTYLLPDNHKTSKRKTKISRKTRNP
TFNEMLVYSGYSKETLRQRELQLSVLSAESLRENFFLGGVTLPLKDFNLSKETVKWYQLT
AATYL
>P32871|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos taurus|Swiss-Prot
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>P42336|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|Swiss-Prot
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>P42337|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|Swiss-Prot
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFREARKYPLHQ
LLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPID
SFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A0G2K344|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rattus norvegicus|Swiss-Prot
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPID
SFTMPSYSRRISTATPYMNGETATKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN
>P42338|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|Swiss-Prot
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRALPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>Q8BTI9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|Swiss-Prot
MPPAMADNLDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRRKMRKFSEAKIQSLVGLSWIDWLKHTYPPEHEPSVLE
NLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEDEASPCDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINR
NSSNLPLPLPPKKTRVISHIWDNNNPFQITLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQ
TIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQTNPYAE
NATALHITFPENKKQPCYYPPFDKIIEKAAELASGDSANVSSRGGKKFLAVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALD
NRRIGQFLFWHLRSEVHTPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLI
KLNAVKLSRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPL
WLVYSSRAFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGD
RSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCA
GYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>Q9Z1L0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rattus norvegicus|Swiss-Prot
MCFRSIMPPAMADTLDIWAVDSQIASDGSISVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEDKIQSLVGLSWIDWLKHTYPPEH
EPSVLENLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEEE
ASPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSSLPLPLPPKKTRVISHVWGNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQ
TNPYAENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASGDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALDNRRIGQFLFWHLRSEVHTPAVSIQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCRYMD
SKMKPLWLVYSNRAFGEDAVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>O00329|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|Swiss-Prot
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSAQTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>O35904|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|Swiss-Prot
MPPGVDCPMEFWTKEESQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLRVSNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYA
LQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGRITEEELQLREILERRGSGELYEHEKDLVWKMRHEVQEH
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQ
ETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>P48736|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|Swiss-Prot
MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>Q9JHG7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|Swiss-Prot
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLD
CLHYWKLMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIANNCIFIVIHRGTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMNISESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
DEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFAEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPSLSSKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRHGDY
VLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSNLP
ESFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGSSGKKTSPHFQKFQDVCVRAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>O02697|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|Swiss-Prot
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSRTNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>Q8NFU5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|Swiss-Prot
MATEPPSPLRVEAPGPPEMRTSPAIESTPEGTPQPAGGRLRFLNGCVPLSHQVAGHMYGK
DKVGILQHPDGTVLKQLQPPPRGPRELEFYNMVYAADCFDGVLLELRKYLPKYYGIWSPP
TAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLMEEIGFLVLG
MRVYHVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWF
ENQKQLNFYASSLLFVYEGSSQPTTTKLNDRTLAEKFLSKGQLSDTEVLEYNNNFHVLSS
TANGKIESSVGKSLSKMYARHRKIYTKKHHSQTSLKVENLEQDNGWKSMSQEHLNGNVLS
QLEKVFYHLPTGCQEIAEVEVRMIDFAHVFPSNTIDEGYVYGLKHLISVLRSILDN
>Q7TT16|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|Swiss-Prot
MAAEPPALRLRPPGSTGDSPPVPRLLGGCVPLSHQVAGHMYGKDKVGILQHPDGTVLKQL
QPPPRGPRELEFYTMVYAADCADAVLLELRKHLPKYYGVWSPPTAPNDVYLKLEDVTHKF
NKPCIMDVKIGRKSYDPFASSEKIQQQVSKYPLMEEIGFLVLGMRVYHLHSDSYETQNQH
YGRGLTKETLKEGVSKFFHNGFCLRKDAIAASIQKVEKILQWFENQKQLNFYASSLLFVY
EGSSQPATTKANDRTLAGRFLSKGPLTDADGLECNNNFHLFGAPPNGMSVGKSLSKAYSR
HRKLYAKKHQSQTSLKVETLEQDNGWRSMSQEHLNGNVLAQLEKVFYHLPAGRPEIPEAE
VRMIDFAHVFPSNTVDEGYVYGLKHLIAVLRSILDS
>Q99NI4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rattus norvegicus|Swiss-Prot
MAAEPPALRLRPPGSTGDSPPVPRLLGGCVPLSHQVAGHMYGKDKVGILQHPDGTVLKQL
QPPPRGPRELEFYTMVYAADCADAVLLELRKHLPKYYGVWSPPSAPNDVYLKLEDVTHKF
NKPCIMDVKIGRKSYDPFASAEKIQQQVSKYPLMEEIGFLVLGMRVYHLHSDSYETQNQH
YGRGLTKETLKEGVSKFFHNGFCLRKDAVAASIQKVEKILQWFENQKQLNFYASSLLFVY
EGSSQPATTKSNDRTLAGRFLSKGALSDADVLECNNNFHLFSSPANGTSVGKSLSKAYSR
HRKLYAKKHQSQTSLKVETLEQDNGWKSMSQEHLNGNVLSQLEKVFYHLPAGRQEIAEAE
VRMIDFAHVFPSNTVDEGYVYGLKHLIAVLRSILDS
>O00443|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|Swiss-Prot
MAQISSNSGFKECPSSHPEPTRAKDVDKEEALQMEAEALAKLQKDRQVTDNQRGFELSSS
TRKKAQVYNKQDYDLMVFPESDSQKRALDIDVEKLTQAELEKLLLDDSFETKKTPVLPVT
PILSPSFSAQLYFRPTIQRGQWPPGLPGPSTYALPSIYPSTYSKQAAFQNGFNPRMPTFP
STEPIYLSLPGQSPYFSYPLTPATPFHPQGSLPIYRPVVSTDMAKLFDKIASTSEFLKNG
KARTDLEITDSKVSNLQVSPKSEDISKFDWLDLDPLSKPKVDNVEVLDHEEEKNVSSLLA
KDPWDAVLLEERSTANCHLERKVNGKSLSVATVTRSQSLNIRTTQLAKAQGHISQKDPNG
TSSLPTGSSLLQEVEVQNEEMAAFCRSITKLKTKFPYTNHRTNPGYLLSPVTAQRNICGE
NASVKVSIDIEGFQLPVTFTCDVSSTVEIIIMQALCWVHDDLNQVDVGSYVLKVCGQEEV
LQNNHCLGSHEHIQNCRKWDTEIRLQLLTFSAMCQNLARTAEDDETPVDLNKHLYQIEKP
CKEAMTRHPVEELLDSYHNQVELALQIENQHRAVDQVIKAVRKICSALDGVETLAITESV
KKLKRAVNLPRSKTADVTSLFGGEDTSRSSTRGSLNPENPVQVSINQLTAAIYDLLRLHA
NSGRSPTDCAQSSKSVKEAWTTTEQLQFTIFAAHGISSNWVSNYEKYYLICSLSHNGKDL
FKPIQSKKVGTYKNFFYLIKWDELIIFPIQISQLPLESVLHLTLFGILNQSSGSSPDSNK
QRKGPEALGKVSLPLFDFKRFLTCGTKLLYLWTSSHTNSVPGTVTKKGYVMERIVLQVDF
PSPAFDIIYTTPQVDRSIIQQHNLETLENDIKGKLLDILHKDSSLGLSKEDKAFLWEKRY
YCFKHPNCLPKILASAPNWKWVNLAKTYSLLHQWPALYPLIALELLDSKFADQEVRSLAV
TWIEAISDDELTDLLPQFVQALKYEIYLNSSLVQFLLSRALGNIQIAHNLYWLLKDALHD
VQFSTRYEHVLGALLSVGGKRLREELLKQTKLVQLLGGVAEKVRQASGSARQVVLQRSME
RVQSFFQKNKCRLPLKPSLVAKELNIKSCSFFSSNAVPLKVTMVNADPMGEEINVMFKVG
EDLRQDMLALQMIKIMDKIWLKEGLDLRMVIFKCLSTGRDRGMVELVPASDTLRKIQVEY
GVTGSFKDKPLAEWLRKYNPSEEEYEKASENFIYSCAGCCVATYVLGICDRHNDNIMLRS
TGHMFHIDFGKFLGHAQMFGSFKRDRAPFVLTSDMAYVINGGEKPTIRFQLFVDLCCQAY
NLIRKQTNLFLNLLSLMIPSGLPELTSIQDLKYVRDALQPQTTDAEATIFFTRLIESSLG
SIATKFNFFIHNLAQLRFSGLPSNDEPILSFSPKTYSFRQDGRIKEVSVFTYHKKYNPDK
HYIYVVRILREGQIEPSFVFRTFDEFQELHNKLSIIFPLWKLPGFPNRMVLGRTHIKDVA
AKRKIELNSYLQSLMNASTDVAECDLVCTFFHPLLRDEKAEGIARSADAGSFSPTPGQIG
GAVKLSISYRNGTLFIMVMHIKDLVTEDGADPNPYVKTYLLPDNHKTSKRKTKISRKTRN
PTFNEMLVYSGYSKETLRQRELQLSVLSAESLRENFFLGGVTLPLKDFNLSKETVKWYQL
TAATYL
>Q61194|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|Swiss-Prot
MAQISNNSEFKQCSSSHPEPIRTKDVNKAEALQMEAEALAKLQKDRQMTDSPRGFELSSS
TRQRTQGFNKQDYDLMVFPELDSQKRAVDIDVEKLTQAELEKILLDDNFETRKPPALPVT
PVLSPSFSTQLYLRPSGQRGQWPPGLCGPSTYTLPSTYPSAYSKQATFQNGFSPRMPTFP
STESVYLRLPGQSPYFSYPLTPATPFHPQGSLPVYRPLVSPDMAKLFEKIASTSEFLKNG
KARTDLEIANSKASVCNLQISPKSEDINKFDWLDLDPLSKPKVDYVEVLEHEEEKKDPVL
LAEDPWDAVLLEERSPSCHLERKVNGKSLSGATVTRSQSLIIRTAQFTKAQGQVSQKDPN
GTSSLPTGSSLLQEFEVQNDEVAAFCQSIMKLKTKFPYTDHCTNPGYLLSPVTVQRNMCG
ENASVKVSIEIEGLQLPVTFTCDVSSTVEIIIMQALCWVHDDLNQVDVGSYILKVCGQEE
VLQNNHCLGSHEHIQNCRKWDTEIKLQLLTLSAMCQNLARTAEDDEAPVDLNKYLYQIEK
PYKEVMTRHPVEELLDSYHYQVELALQTENQHRAVDQVIKAVRKICSALDGVETPSVTEA
VKKLKRAVNLPRNKSADVTSLSGSDTRKNSTKGSLNPENPVQVSMDHLTTAIYDLLRLHA
NSSRCSTACPRGSRNIKEAWTATEQLQFTVYAAHGISSNWVSNYEKYYLICSLSHNGKDL
FKPIQSKKVGTYKNFFYLIKWDELIIFPIQISQLPLESVLHLTLFGVLNQSSGSSPDSNK
QRKGPEALGKVSLTLFDFKRFLTCGTKLLYLWTSSHTNSIPGAIPKKSYVMERIVLQVDF
PSPAFDIIYTSPQIDRNIIQQDKLETLESDIKGKLLDIIHRDSSFGLSKEDKVFLWENRY
YCLKHPNCLPKILASAPNWKWANLAKTYSLLHQWPPLCPLAALELLDAKFADQEVRSLAV
SWMEAISDDELADLLPQFVQALKYEIYLNSSLVRFLLSRALGNIQIAHSLYWLLKDALHD
THFGSRYEHVLGALLSVGGKGLREELSKQMKLVQLLGGVAEKVRQASGSTRQVVLQKSME
RVQSFFLRNKCRLPLKPSLVAKELNIKSCSFFSSNAMPLKVTMVNADPLGEEINVMFKVG
EDLRQDMLALQMIKIMDKIWLKEGLDLRMVIFRCLSTGRDRGMVELVPASDTLRKIQVEY
GVTGSFKDKPLAEWLRKYNPSEEEYEKASENFIYSCAGCCVATYVLGICDRHNDNIMLRS
TGHMFHIDFGKFLGHAQMFGSFKRDRAPFVLTSDMAYVINGGEKPTIRFQLFVDLCCQAY
NLIRKQTNLFLNLLSLMIPSGLPELTSIQDLKYVRDALQPQTTDAEATIFFTRLIESSLG
SIATKFNFFIHNLAQLRFSGLPSNDEPILSFSPKTYSFRQDGRIKEVSVFTYHKKYNPDK
HYIYVVRILREGHLEPSFVFRTFDEFQELHNKLSIIFPLWKLPGFPNRMVLGRTHIKDVA
AKRKIELNSYLQSLMNASTDVAECDLVCTFFHPLLRDEKAEGIARSAGAVPFSPTLGQIG
GAVKLSVSYRNGTLFIMVMHIKDLVTEDGADPNPYVKTYLLPDTHKTSKRKTKISRKTRN
PTFNEMLVYSGYSKETLRQRELQLSVLSAESLRENFFLGGITLPLKDFNLSKETVKWYQL
TAATYL
>A0A6J3QBD9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tursiops truncatus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFSVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPLKKPASVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEEVSWGPWAVGRGPGCSPHRPPTSTCAPQQLQLRE
ILERRGSGELYEHEKDLVWKMRHEIQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPE
LPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFL
LDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLK
ALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMD
SKMKPLWVLYSNEEAGSDGTVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPY
GCLSTGDHTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFI
LTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSK
DIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P7I1X9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Parambassis ranga|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLINIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVNHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCITVGRLPHLMLVSKDSLYSQLPGS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNMPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKSLT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWLKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A8D0SSP5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MELENYEQPVVLREDNRCRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A287BCU4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MCFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDYPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKSRGGKKFLAVLKEILDRDPLSQLCENEMDL
IWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQ
YVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWH
LRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLKTLNSLIKLNAMKLNRAK
GKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGE
DSIGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTS
ETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGI
GDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTE
KFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEA
LKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C8CBW6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPAMTNLMDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQACFSPQLEPGGG
ATPVTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISA
IGAVVNRKSSNPPLPLPPKRRGPSQVNTCVWEVSTHFKIVLIKGSKVNAEETAKIQVRAG
LFHGTELLCKPAVSSESSGRSEHVWNRTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKS
TKNAHINKYQTIRKSGKVHYPVAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPI
GTIQTNPYTENTTALHIHLPDYNPHTILFPPFDKILEKAAEIAGSSDCLPMGRGGKKFHI
ELKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQ
IWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCAL
TRFLLNRAQCNRNIGHFLFWHLRSEMHMPAVAVQFSLILEAYCRGSIPHIEVLKKQVEAL
SKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSG
INVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEA
NLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNS
GDALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFG
IKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTA
GLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A6I9I0F6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vicugna pacos|TrEMBL
MELENYEPPVVLREDNCRRRRRMKQRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHLVQRSTPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILHSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPNPDLDQVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVYVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDHGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIDEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIDYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A452H4H8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gopherus agassizii|TrEMBL
MPPAVTDILDIWAVDSQIGADGLISVDFLLPTGTYINLDVPRDATICHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVKEFRSKMRRISEEKLLSLVGLSWVDWLKHSYPPEQEPSIPE
NFQDKLYGGNLVVAIHFDKCQDVFSFQVSPNINPVKLNELAIRKRLTIHGKEDEVDPSDY
VLQISGRLEYIFGDHPLIQFQYIRKCVMNRILPHLTLVECCSIKKMCEQEMIAIEGAINR
KSSNLPLPLPPKKTRTVTQLTHSVWDMSNPFKIMLLKGNKLNTEETAKVHVRAGLFHGTE
LLCKPIVSAEISGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKTINP
SKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDLLLHSWTSFPDELEEMLNPMGTVRTN
PYTENATALHIKFQEYSKLPIYYPPFDKILEKAAEIAKSSENAGMPGRGGKKFYIELKEI
MERDPLTQLCENEMDLIWTLRYDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWSKL
PPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLV
ERALANRRIGQMLFWHLRSEVHIPAVSIQFGVILEAYCRGSIAHMKVLSKQVEALSKLKT
LNSIIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELYVEKCKYMDS
KMKPLWIVYNNKMFGGDLLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGC
LATGDHSGLIEAVSAAETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A1A8KFU1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius kuhntae|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREAALNTIKHELFKEVRKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDSSGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYTQLPTD
SFVMPSYSRRISTATSYMNGEAASKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSVCSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVASKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNFPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSPECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A1A8Q6S4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius rachovii|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLDCLRETPLISIKQQLFVEARKFPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDSEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIVSPTNSKQKYTLKVSHDSLPEQLIAESIRKKTRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIVVGRLPHLMLVSKDSLYSQLPAS
GYITPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYINVNIRDIDKIYVRT
GIYHGGEPMCDNVNTQRVPCSHPRWNEWLTYDLYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYSYCHGLSSRLACDSTVSASDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCINIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMESESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKVQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEGYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQTFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A1A8PLA0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius rachovii|TrEMBL
MPPAMTDLLDIWASHSPLAGHALEKITVDFLLPTGIYIQMDVPRDATIQHIKLLLWKQAQ
NFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRCKMFRITEEKMQQAQVMTCAEWLQACCSPQLEPT
AATLVTDGVNDRPADLKVFIHFDQSQDSTSLKVPMSCTPSELMEIAVKKWLTTHAPEDEA
YSRQYVLRVSQCLEFLCGDHPLIQYKYIRNCLQAKESPHLTLVHTSTVKIMFDKEMSAIG
AVVSRKSSNPPLPLPPKRRTPTQVHTSVWNVSKPFRIDLLKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSDSSGRSEHIWKNNTLKFELSVSDLPRMTRLCFAIYAVTDKVKKQKST
KNAHSSKYQTIRKAGKVLYPIAWVNTMVFDYRGQLKTGDVILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHPVIFPPFDKILEKAAQLVGVIEQPIGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVSCLHDMSDEELLQYLLQLVQVLRYEPYYDCPLTH
FLLERAQRNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSEALSDLTSPLNPSVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLMSGDALGIIFKNGDDLRQDMLTLQILKLMDLLWKESNL
DLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQEGKTGNTEKFGSFRKYCEEAYLILRRNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKNDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A2Y9RBH4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Trichechus manatus latirostris|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSVPVDFLLPTGIYIQLEVPREATISHIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGD
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEEKIQSLVGLSWMDWLKHTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAVQKRLTIHGKEDE
VNPYDYVLQVSGRIEYVFGDHPLIQFQYIRNCVMNRTLPHFTLVECCKIKKMYEQEMIAI
DAAINRNSSNLPLPLPPKKTRIISVGFMGEPLITPKHVWENNHPFQIVLVKGNKLNTEET
VKVHVRAGLFHGTELLCKTIVSAEISGKSDHIWNELLEFDINTCDLPRMARLCFAVYAVL
DKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDITLHSWSSFPDE
LEEMLNPMGTVQTNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDGANVSS
RGGKKFLAVLKEILDRDPLSQLCENETDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDV
AQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVSCLRQMSDEELSQYLLQLVQVLKY
EPFLDCALSRFLLERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKV
LSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVIL
SELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWK
EAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEY
NSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSK
FGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGSLFITLFALML
TAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDY
KS
>A0A6D2XVS3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan troglodytes|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRALPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>U3DZL6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callithrix jacchus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A5F4C2B1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A1A8AQH9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius furzeri|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREAALNTIKHELFKEVRKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDSSGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYTQLPTD
SFVMPSYSRRISTATSYMNGEAASKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSVCSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVASKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNFPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSPECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A1S3NTW2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo salar|TrEMBL
MPPAMTDDLDLWAAHSQLSGEDMVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFCPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQACFSPQLEPGGG
ATPVTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSSVQAMFEKEISA
IGAVVNRKSSNPPLPLPPKRRGPSQVNTCVWEVSTQFKIVLIKGSKVNAEESAKVQVRAG
LFHGTELLCKPVVSSESSGRSEHVWNRTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKS
TKNAHINKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPI
GTIQTNPYTENCTALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCSTMGRGGKKFHI
ELKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQ
IWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCAL
TRFLLNRAQCNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEAL
SKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSG
INVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEA
NLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNS
GDALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFG
IKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTA
GLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A6J2CIP2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zalophus californianus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3Q7THN3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vulpes vulpes|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYCFPLQLEPSARSWGP
GTLRVPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMR
QEAYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A1U7RNM5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alligator sinensis|TrEMBL
MLPGIYCPVEFWSKEENQNIQVDFLLPTGIYLSLPVSCNASLGTIKEVVWQHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVSDPEVSDFRTKMRQFCEERAAKRQQLSWMAWMEYSFPLQLEPLAKGLGT
SPLHVPHKNIFVNVMFESGGESFTFQISPREYPITLMSYAIKKQATVFRHQTVESPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHQGLMPHLTMVRFSTIIAMRDEQTNCIAHPPKMG
AKPPPLPKKKPNSGSLWSLEQPFYIDLVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKAGECCLHMWSSFPDEKGELLNPMGTVQSNPNTESAAALVICFPNVSV
HPVHYPAYEQLLDLGRNGEHSRATLDDPEEKQQLKEILERRSHTELYEHEKDLMWKMRYH
IRDQYPEALAKLLIITKWNKHEDVAQMISLLHTWPELPVLNALELLDFSFPDRYVGFFTI
NSLKKLTDEELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQRATKPQTKEMMHV
CMKQETYLEALSNLLSPLNPNIILAEVCVEQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRD
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6J2FRJ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pipra filicauda|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMAVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>Q8CI98|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|TrEMBL
MPPGVDCPMEFWTKEESQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLRVSNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYA
LQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGRITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMR
QETYMEALSHLQSPLDPSTLLEEVCSVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFK
NGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQL
NKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGY
CERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKF
NEALRESWKTKVNWLAHNVSKDNRQ
>Q3T9Y0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|TrEMBL
MPPGVDCPMEFWTKEESQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLRVSNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYA
LQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGRITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQLSQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAI
KSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHV
PSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHM
CMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGII
FKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANI
QLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFR
GYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRV
KFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3B1KEL8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MPPGVCYGMQDVWEKEGREQVTMEFLLPTGIYLSFPVARSDTIGAIKKMVWKNARSEPLY
SVLSDPDAYVFTCINRTAEREDLEDEQRRLCDVRPFMPVLRLVAREGDRVEKLINTQISL
LIGKGLHEFDSQKNHEVNEFRTKMRSFCEEKAQERQRLPWHQWMEYNFPCDLEPFSIVAQ
SGKSRSVKKIIVNVKFEASEESFMLQVDPQDQPVVLMRSALRKKATVFRQSKQEKPEDYT
LQVNGRMEFIYGKYPVCQFKYIFSCLCGGQTPHLTMVHHSAILKYQEEQGSLSNQVSKSR
SLSKPPPLPLKKQNTTSLWSIHEPFFIHLVQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVSVCSDPRWDQKLVFDISLCDLPRMSRLCFALYGVLEKSKKQRSTKKKNKKADCPL
VWVNTMVFDYKDQLKTGEVVLSTWPSAPDDKGDLLNPMGTVERNPNIDSTAGLIIHFPNF
RPHPLYYPPLDKLNEAERNGEKISASKEEHLKLKEIVDNKNHTEFFEDEKELLWKLRGEV
RAHYPESLSKLLLITKWNKHEDVAQMVCLLRKWRDLPALHALELLDYSFPDPHVRSFTIR
CLRKLRDDELFQYLLQLVQVLKYESYLDCDLSTFLLERALSNKRIGHFLYWHLRSEMHIS
SVSLRFGLILEAYCRGSIYHMKNLMKQNEALNKMKALNDFVKSGCQKSTSKSQITEDMKL
CIKQDTYLEALSEIVSPLNPNILLCEICTDKCKFMDSKMKPLWLMYRNKWLQSDSVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMVPYGCLSTGNKTGVIEVVKNSDTIANIQ
RNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRENGQLFHIDFGHFLGNFKAKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRE
YCELAYKILCRNGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEDEALKNFKVK
FNEALRESWKTKVNWMVHTVAKDNR
>W5LKU0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLISVKQQLFAEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPSVESSPQLPQH
IYCKLDKGRLIVTIWVVVSPSNAKQKYTLKIAHDCLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCITVGKLPHLMLVSKDSLYSQLPAS
GFVAPSYSRRTPQPSPCPGGSDPSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLTDLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
SFNQMVVFPDEQQIEEHANWIVSRELGYNYSLSLSNRLACDSTISQAELEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLAVKWNSRDEVSQMYCLLRDWPLMQPESAL
ELLDCNFPDPMVREFALRCLIQGLTDDKISQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KHEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKEKNKGEGYDKAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGMQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>H3DCH7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tetraodon nigroviridis|TrEMBL
MPPGKYGMQEEWEKEGDQRIMMDFLLPTGIFLKFPVSRNDTIKIIKKMVWKNAQNEALYA
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCFLRLVAREGDRVEKLTNTQISQL
TGKGLHEFEAQKNHEVDEFRAKMRAFCEEKAQERQMLPWLEWMEYNFPCDLEPCCSPVDC
GATKSKNTKIFINVKFEACDESFMLQQDPQDLPVALMKAALKKKATVFRSVRQEPEDYTL
QVNGRWEFIYGRHPLSQFKYIFSCLRNGQNPHLTMVHHSTIRKHQEEQGHMCSQVYKGRS
QSRPPPLPLKKQNTSSLWSINEPFYIRLLHGSRVNAAEGMKLVVQAGLFHGSELLCKVVT
SSEVAVCSEPVWDQRLEFDISVSDLPRMSRLCFALYAVIEKNKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPVTDDKGDLLNPMGTVEKNPNVDSAAGLLIHFPN
VRPHPLYYPSPEKISDMEKNGFAVIATKEEHMKLKEIMDNKNYTEIFEDEKELLWKLRSV
VRDHYPESLSKLLLITKWNKREDVVQMVGLLRHWPDLPAIHALELLDYSFPDPSVAFTVR
CLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNSRIGHFLFWHLNQKFMMP
SVSLRFSLMLEAYCRGNIWHIKLLIKQNEALLKMKTLSDIVKTGSQKMTVDDLKLCIKQE
SYVETLSDLLSPLNPSVFLAEICADKCRFMDSKMKPLWLMYKSPWAQGDMMGIIFKNGDD
LDLRQDMLTLQMIRLMENLWKKEGLDLRMIPYGCLSTGDKMGLIEVVKNSDTIANIQRNS
SNSAATAAFNKDALLNWLKSKNPEGKLEKAIEEFTLSCAGYCVATYVLGIGDRHNDNIMI
RETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCE
RAYKILCRNGMLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEEEALKNFKVKFNE
ALRESWKTKVNWMMHSLAKDNRP
>A0A1V4K3S9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Patagioenas fasciata monilis|TrEMBL
MPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQLLQDESSYIFVSVTQ
EAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPE
VQDFRRNILNVCKEAVELRDANAPHSRALYVCPPNVESSSELPKHIYNKLDKGQIIVVIW
VIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVC
GCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLDTFTMPSYSRRISTAT
PYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQR
VPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINMFDYTDT
LVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSNPVKFPDMTVIEEH
ANWTISRELGFNYSCAGLSNRIARDNELRESDKEQLRAICTRDPLSEITEQEKDFLWSHR
HYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRAFA
VRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTNQRIGHFFFWHLKSEM
HNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFL
VEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQ
NNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSH
TIMQIQCKGGLKGALQFNSHTLHQWLRDKNKGEMYDAAIDLFTRSCAGYCVATFILGIGD
RHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTR
EFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEA
LEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C0B893|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Buteo japonicus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPAKNIFVNVRFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGQTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARL
CFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKG
ELLNPMGTVQCNPNTESAAALVICFPSVALHPVYYPSFEQLLELGRNGEQPRQKLQLKEI
LERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPEL
PVLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLL
DRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKA
LNDFVKVSSQKATKPQTKEMMHMCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDS
KMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGC
LSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILT
YDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDI
QYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P3I1S2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bison bison bison|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEGSWGPGSYLDCELTKFLLDRALANRRIGHFLFW
HLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKP
QTKELMHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAG
SDGTVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVL
HSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVL
GIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNN
SEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEE
EALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A851P8P1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Penelope pileata|TrEMBL
MELEDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMLLLE
IAGNCTVEQMKAQVWMRAIEMSQTTEFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPSSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKDRCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C2MP62|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cricetulus griseus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
SFTMPSYSRRISTATPYMNGETTTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3B5AA19|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Stegastes partitus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDLAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A851X877|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eolophus roseicapilla|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GPLHIPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKTA
AKPPPLPKKKPNYGSLWSLEQSFYIQLVQGSKVNADEGMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWQQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAAEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMQSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKNNRQ
>A0A8J8YMM1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca mulatta|TrEMBL
MELENYEQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSMASDFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPAVSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDTCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8C7IND0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPRPSSGELWGMHLMPPSIQVDCLLPNGMILTLVCTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANCNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCGTIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNNSWNKLKNSCKNIFSLQLFHIDFGHFL
DHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLF
INLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWI
FHTIRQHAMN
>A0A8C4APY8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLLTIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRSILSVCREAMEEREMGGAHSQALYVYPPNVESSPELPPH
IYTKLDKGRLIVTIWVIVSPSNAKQKYTLKIGHDSLPEQLIAEAIRKKTRSMHLSAAQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYVRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVAPSYSRRTPQPSPCPGGGDPSTPRTLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLTDVPRAARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDTLVGGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFP
SFSQTVVFPDEQQIEEHANWTISRELGYNYSLGMSSRLACDSSVSQTDVEQLRILCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKDWPLIQPESAL
ELLDCNFPDPAVRDFSLRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMEKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A8C4BJB2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPGVFGMQDVWEKDGQQVTVEFLLPTGIYLTLEVSCSDTIGTIKKMLWRAARGEPLFGA
LSDPDAYVFTCINLTAEREDLEDEQRRLCDVRPFLPILRLVAREGDRVEKLINTQISHLI
GKGLHEFDSQKNHEVSEFRTKMRAFCEERAQERQRLPWYEWMESSFPCDLEPCSGLLKSS
KFHNFKKVFVNVKFEGSEESFMLQLDPQDLPVMLMKNALKKKATVFRPVRQEKPEDYTLQ
VLGRWEFIYGKHPLCQFKYIWCCMHEAQTPYLTMVHHSTITKYQEEQSCLTNQVTKTRSS
SKPPPLPLKKQNTTSLWTIQEPFYVQLVQGSRVNADEGMKLVVQAGLFHGSELLCKVVTS
NEVNVSSEPLWDQKLVFDISVGDLPRMTRLCLALYAVVGTTKKARSTKKKNKRADCPLAW
VNTMVFDYKDQLKTGDFSLSAWPSVPDEKSDLLNPMGTVEKNPNIDSAAGLLIRFPNIRP
HPLCYPPLDKISELPCLDGETSVATMEEHMKLKEIVDNKNQTEIFEDEKELLWKLRVEMR
DHYPESLSKLLLIGKWNKHEDVAQMVWLLRKWPDLPVLHALELLDYRFPDPYVRSFTIKC
LRKLRDDELFRYLLQLVQVLKYESYLDCDLTTFLLERALSNKNIGHFLFWHLRSEMHVSS
ASLRFGLILEAYCRGNLYHIKSFMKQNEALNKMKALNDFVKSGSQKATRSQTIEDMKVCI
RQEAYMEALSDMLSPLSPSIILSEICTEKCKFMDSKMKPLWLMYKSKVAQADTVGIIFKN
GDDLRQDMLTLQMLELMDVLWKREGLDLRMVPYGCLSTGNKTGLIEVVKNSDTIANIQRN
NSNSAATAAFNKDALLNWLKSKNPGDKLEEAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYC
EQAYKILCRNGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKIFKVKFN
EALRESWKTKVNWMMHSVAKDNR
>A0A8C0FS01|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLERSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQVGDQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIIT
KWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDQYVGSFAINSLKKLTDHELFQYLL
QLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCR
GSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHVCMKQETYLEALSHLQS
PLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMI
QLMDILWKQEGLDLSDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHI
DFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRH
GLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTK
VNWLAHNVSKDNRQ
>A0A836D0Q9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ovis aries|TrEMBL
MEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFHMLSDPEAY
VFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHEF
DSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGPGTLRIPNR
ALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYTLQVNGKHE
YLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRTKPPPIPM
KKPSSMSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSVCSE
PVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDY
KDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAPHPVYYPSL
DKVMVVLNWGHLVSQGTSGNLQLREILERRGSGELYEHEKDLVWKMRHEIQEHFPEALAR
LLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDEL
FQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSVALRFGLIM
EAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVCSQKTPKPQAKELMHLCMRQETYLEAL
SHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKNGDDLRQDM
LTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATA
AFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLF
HIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCETAYTILR
RHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWK
TKVNWLAHNVSKDNRQ
>A0A836AHH4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ovis aries|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A3P9HUC9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MPPAMTDLVDIWAAHSPLDGQAPVHVTMDFLLPTGIYIQMEVPREATIQHIKLLLWKQAK
SFPLSSFLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVFRLVTRNCGRAERLLD
SKIGVIIGKGLHELDGINDQEVKDFRSKMQRLSEERMQRVQMMSFTEWLQACFSPQLEPS
AGTAIADGANDWPADLKVIIHFDQSQDSTSLKVLSSCTPSVLIEIALKKWQTTHAPEEET
NKDKHILRVSQCLDFLCGDHPLIQYKYIRSCLQAKESPHLTLVHINAVKAIFDKENAAIG
AVVSRKSSNPPLPLPPKKRAPTVQVRAGLFHGTELLCKPAVSSESSGRSNHSLENNTLEF
EISVCDLPRMTRLCFAIYAIMEKVKKKSYKNPHINKYQTIRKAGKVHYPIAWVNTMVFDY
KGQLKTGDTILHCWSSFPDELEEMLNPIGTVRINPYPENATALHIHFPDYGPHPIVFPPF
DKILEKAAEIAGSSDSTPIGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRLDCREN
FPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVSCLR
DMSDEELLQYLLQLVQVLRYEPYYDCALTHFLLERAQKNRKIGHFLFWHLRSEIHMPAVS
IQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNTRSKTKEAMLTKEAM
ITCLKQSGYSEALSDLHSPLNPNVLLSDINVEKCRYMDSKMKPLWIVYNNKLMSSDTLGI
IFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIAN
IQLTSSNVAAAAAFNKDALLNWLKERNSGDALERAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSF
RQYCEEAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSDEEALKQFR
QKFDEALRESWTTKVNWMAHNVAKDNRS
>H2M0C9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MDRQSIQVSDEEPEVPREECRRRRRKKAITSSSCVSMDQITIEFVMPSAARSGSGPDILT
LDVAGNWTVEQVKAQVWMKAVTLNLCPDFYQRLSPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIPYWRALKKGVGRIQMVTRPQLSEESLQYQRYLNCLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVNNSHILVVIHIGMVSQTIKVSIN
DTPSQVLASFFAKTANKRVLLGIPDDVCEADFVLRVCGREEFLYGEKPLQNFNWIRQCLK
NGEEIHLLLEKPPDPELDVVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPTLPKVPELVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKPTQTPASKGSSHYDNSAGTGSVEGKTKNRLLFYVNLLLVDH
RSLLRQGEFILHMWKMPEKSDESSSSINADKLTSATNPDKSSSMAVAILLDKYCYPVVLP
KSRDVGRDSGAGEEMEGGERGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRQEC
MRDPRAYPKLLGSVKWGKQEDVLATHRLLERSNAWDTSGLDVGLAMQLLDCHYSDSHVRS
MAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGESMLQDFRKQVEMTMALQKVTRDIKAIAADKYDVSAQ
VVFQLRQKLETLQSSGLPETFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTT
LSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETECLDLCLLPYGCISTGNKIGMIEIV
KDATTIANIQQRVVGSTGAFKDEILHQWLRDKCVSEDKFQQAVERFLLSCGGYCVATYVL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKS
SPHFLKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEE
EAQRHLLDQIEICREKGWMVQVNWFVHLVLGIKQGVEKRST
>A0A091RQ15|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nestor notabilis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYILDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMKLQSFDDIAYIRKTLA
LDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A091S137|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nestor notabilis|TrEMBL
SRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGP
GTGPLHIPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAIKKQATVFRHETVEKPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPK
AAAKPPPLPKKKPNYGSLWSLEQSFYIQLVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMR
YDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSF
AVNSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEM
HVPAVALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMM
HVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGI
IFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIAN
IQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERF
RGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFR
LKFNEALRESWKTKVNWLAHNVSKNNR
>A0A6G1QA03|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Channa argus|TrEMBL
MPPRPSSGELWGMHLMPPRILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAELEEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLKDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPFD
NFTMPSYARRISTATPYMNGETATKSLWAINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SCPVKFPDMKTIEDHANWNISRELGFNYCHTSLSNRLARDNPLTDADNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCLNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRYFSTLLSKSPLLNDC
YLCMSLQILDDCRMMSSAKRPLWLNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQII
RIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTL
HQWLKDKNKGEMYDQAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHF
LDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANL
FINLFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDW
IFHTIRQHAMN
>A0A8C4X7Z9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Erpetoichthys calabaricus|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCCLPNSILVTLECLREATLLSIKRDLFSEARKYPLFH
LLQEESSYIFVGVTQEAEREEFYDETRRLCDLRLFQPILKVIEPVGNREEKILNREIGFA
IGMPICEFELMKDTEVQDFRRNILTVCREAIEQREAGGAHSQALYVYPPNVESTPELPKH
IYNKLDKGRLIVTIWVIVSPTNDKQKYTLKIPHDCLPEQVIAEAIRKKTRSMHLSPEQLR
LCVQEYQGKYILKVCGCDEYLLERLPLSQYKYIRSCITIGRLPHLMLMSKDSLYSQLPAN
GFLMPSYGRRTPQPSPAGTANGGAGDSTSCRSLWAFNSLLRIRVLCATYVNVNIRDIDKI
YVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDLPRSARLCLSICSVKGRKG
AKEEYCPLAWGNVNLFDYKDTLVTGKMALNLWPVPHGLEDLLNPIGVAGSNPNKETPCLE
LEFNWFGNSVKFPDNQQTEEHANWCISRELGYNYCLVGASNRLARDNVLSDSDIDQLRSI
CHRDPLSELTEQEKDFLWRHRQYCVSMPEILPKLLLSVKWNSRDEVAQMYCLLKDWPLMK
PELALELLDCNFPDPVVRDFALKCLVKGLTDDKLSQYLLQLVQVLKYEQYLDNPLARFLI
KKALTNQRIGHFFFWHLKSEMHNKTVSLRFGLLLEAFCRACGMYLKHLNRQVEAMEKLIN
LTDILKQEKKDEPPKTQMKFLVEQMSRPDYMEALQGFVCPLNPVHQLGNLRLEECRFMSS
AKRPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRML
PYGCLSIGDCVGLIEVVKNSHTIMQIQCKGGLKTALQFNSNALHQWLKEKNKGDTYDAAI
DLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPF
VLTQDFLIVISKGSPECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSLLLGCGMPELQ
SFDDIAYLRKTLALDKMEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPLSEASHD
>A0A6G1Q336|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Channa argus|TrEMBL
MPPGKYGMQEEWEKEGDHQIMMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFN
ALGDPDAYVFTCINQTAEREDLEEESRRISDVRPFMHVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMHSFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPQC
GNTKSKTSRKILINIKFEASDESFMLQQDPQDLPVVLMRSALKKKATVFRSVRQEPEDYT
LQVAGRWEFIYGKHPLCQFKYIFSCLRNVQNPHLIMVHHSTISKYQEEQGRMCSQVFKSR
SLSRPPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
SSSEVGVCSEPSWDQKLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDRSDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPYPLYYPPLDKISDMERNGDVTFPTKEEYMKLKEIMDSKNYTEIFEDEKELLWKLRTEV
RSLYPESLSKLLLITKWSKREDVVQMVSLLRNWPDLPAIHALELLDYSFPDPAVRSFTIR
CLRKLSDDELLQYLIQLVQVLKYESYLDCDLAIFLLERALSNRRIGHFLFWHLRSEIHVA
SVSLRFGLILEAYCRGNIYHMKLLTKQNEALGKMKALSDFVKSGSQKMTVDDLKLCIKQE
SYLEALSDLLSPLNPSIILSQICADKCRFMDSKMKPLWLLYKNPGTQGDMVGIIFKNGDD
LRQDMLTLQMIQLMENLWKMEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSN
SAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERA
YKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEDEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A8C5HE99|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
MDSELMQVSDEEPELLQEDSLTRRRRRRRKKAITSPSCASMDHITVEFILPTNSHGGSGP
DSLQLEVAGNWTVEQVKAQVWLKAVTLNLSFDFYQRLSPDHCILLYQKKGTVCEIYDKHQ
VFQTLDCIRYWRALKKDVGRIQLVPCPQPSDESLQYQRDLNYLIGYDVTDVSNVHDDELE
FTRRKLLTPRRIELLDRDPRLYSMDPWVTCKPLPKHLLSKVNNGHILLVIHMSTASQTIK
VSINDTPSQVLMSFFTKTANKRALLGIPDNISESDFVLRVCGREEYLYGERPLQNFNWIR
QCLKNGEEIHLVLTAPPDPAMDLVQREDWAQVDDCTGVAGTHEQLTIEEKDHERVFTISM
WDCNRKFRVKVLGIDIPALPKVPELIVFIEASIFHGQQLLAQERTTSKSFSEEVLWNCWL
EFNIKIKDLPKGARLNLQFYKLSFGSASSSTFLGKNKSRLLYYVNLLLVDHRSLLRQGEF
ILHMWKMPEKSDESSSSINADKLTSATNPDKASSMAVVILLDKYCYPVVLPKSRESVSAA
KEAEGCDRGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLS
SVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSIAVRKLETLDDD
DVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSKHYQQRYA
VLLEAYLRGCGGDLLTDFQKQVEMTEALQKVTREMKATSADKYDVTAQVVFLLRQKLETL
QSTGLPQSFRVPYDPGLKAGALLIEQCKVMASKKKPLWLQFRRADPTSRSKDPIGIIFKD
GDDLRQDMLILQILLIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIANIQQS
VVGSTGAFKDEILHQWLREKCVREDKFQQAVERFLLSCGGYCVATYVLGIGDRHNDNIMI
TESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLFVMGTSGKKSSPHFQKFQDVCV
KAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEI
CREKGWMVQINWFVHLVLGIKQGVEKQST
>A0A8C5I2L0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
AMVWKNARNEALFNGLGDPEGYVFTCINQTAVREELEEESRRIRDVRPFMCVLRLVAREG
DRVEKLTNTQISLLIGKGLHEFEAQKNHEVNEFRSKMRSFCEEKAQKRQGLPWQQWMEYS
FPCDLEPCSAKSKNKKKIFINVKFEASDESFMLQQEPQDLPLALMRSALKKKATVFRSLR
QEPEDYTLQVNGRWEFIFGKHPLCQFKQNTSSLWAINKPFNIHLLQGSRVNADEGMKVSV
RAGLYHGSELLCKVVTSSEVTVCSEPLWDQKLDFDINVADLPRMSRLCFALYAIIEKAKK
PRGTKKKNKKADCPIAWVNTMVFDHKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNP
NVDSAAGLLIRFPNILPHPLYYPPLDKPHLKRTTPFFRFVSQKKMYTKLKEIMDNKNHTE
FFEDEKELLWKLRTDIRDCYPESLSKLLLITKWNKREDVVQMVSLLESWPELPAIHALEL
LDYSFPDPAIRSFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCVLTTFLLERALANRR
IGHFLFWYLRSEIHVASVSLRFGLILEAYCRGNIHHMKVLTKQNQALVKMKALNDFVKSG
SQKMTVEDLRLCVKQESYMEALSDLLSPLNPSVILAEICADKCRFMDSKMKPLWLMYRNP
WPHADMLGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEV
VKNSDTIANIQLNSSTSAATAAFNKDALLNWLKSKNPEDKLEQAIEEFTLSCAGYCVATY
VLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGKT
NNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKS
EDEALKNFKVKFTEALRESWKTKVNWMMHSLAKDNRP
>A0A6A5F6V1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Perca fluviatilis|TrEMBL
MPPGKYGMQEEGDQELMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNARSEALFSALGD
PDAYVFTCINQTAEREELEEESRRISDVRPFMGVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFEAQKNHEVNEFRAKMRAFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPECGSVK
SKNTKKIFINVKFEACDESFMLQQDLQDFPLALMKSALKKKATVFRSVRQEPEDYTLQVN
GRWEFIYGKHPMCQFKYMFSCLRNNQIPHLTMVHHSTISKYQEEQGRMSSQGYKTRSLSR
PPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTTSE
VTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVN
TMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHP
LYYPPLDKVSDMEKNGDAAIVTKEECMKLKEIMDNKNHTEFFEDEKDLLWKLRTEVRDHY
HESLSKLLLITKWNRREDVVQMMSLLRTWRDLPAIHALELLDYSFPDPVVRSFTIRCLRK
LSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLRSEIHVASVSL
RFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDFVKSGSQKMTADDLKLCIRQESYLE
ALSDLLSPLNPSIILAEICADKCRFMDSKMKPIWLMYNPCTQEDMVGIIFKNGDDLRQDM
LTLQMIQLMENLWKREGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATA
AFNKDALLNWLKSKNPEDKLDRAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLF
HIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILC
RNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWK
TKVNWMMHSLAKDNRP
>A0A6A5EWZ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Perca fluviatilis|TrEMBL
MVEVITVDFLLPTGIYIQMEVPREATIQHIKLLLWKQAQSFPLFPPLGEMESHMFECVNQ
AAVHEELEDETRRLCDVRPFLPVLKLVTRSCGRAERLLDSKIGVLIGKGLHELDAINDQE
VKDFRCKMFRLSEERMQQVQMMTCTEWLQACFSPQLEPLAGTAITDGLNERPADLKVIIH
FDQSQDSASLKVPSSCIPSDLMELAVKKWLTTHGPEEEVWLGQYILRVSHCLEFLCGEQP
LIQYKYIRTCMQAKESPHLTLVHTSTVKGMFDKEISAIRAVVSRKSSNPPLPLPPKRRVP
TQLQKCVWDVSSPFKIVLVNGNKVNAEETAKVQVRAGLFHGTELLCKPAVSSESSGRSDH
TWKDSTLEFDLSVCDLPRMTRLCFAIYAVMDKVKKQKSTKNAHINKYQTIRKAGKVHYPI
AWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATALHIHFPEY
SSHSIVFPPFDKILEKAAEIAGASDCVPMGRGGKKFHIELKEIMERDPLSQLCENEKDLI
WTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQY
VREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGNRKIGHFLFWHL
RSEIHMPAVSVQFALMLEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARNKT
KEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGINVERCRYMDSKMKPLWIVYDN
KLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRAGLIE
VVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNTGDALDRAIEEFTLSCAGYCVAT
YVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTRRHSIFRQYCE
EAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEDALKQFRQKFDE
ALRESWTTKVNWMAHNVAKDNRS
>A0A8D3BV32|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPGKYGMQEEWEKEGVQEIMMDFLLPTGILLKFPVSRNDTIKSIKKMVWKNARSEALFC
GLGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRAEKLINTQISLL
IGKGLHEFEAQKNHEVNEFRTKMCIFCEEKAQERQMLPWQQWMEYNFPCDLEPCCTPFDW
EKLFMLQQDPQDHPVALMRSALKKKANVFRSVRQEPEDYTLQVNGRWEYIYGKHPMCQFK
YIFSCLRNGQNPHLTMVHHSTISKFQEEQGQMCSQEYKSRSLSRPPPLPLKKVRGQRTAG
LVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEK
TKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVE
KNPNVDSAAGLLIRFANIRPHPLYYPPLDKVLVPKRLCWYMKLKEIMDNKNYTEFFEDEK
ELLWHLRTEVRDRYPENLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFP
DPAIRSFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLF
WHLRSEIHVASVTLRFGLILEAYCRGNIHHIKLLTKQNEALSKMKTLSDFVKSGSQKLTA
EDLKLCIRQESYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNNWAPEDM
VGIIFKKGDDLRQDMLTLQMIQLMETLWKREGLDLRMIPYGCLSTGNKMGLIEVVENSDT
IANIQRNNSNIRGASLTQRLDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYK
ILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDNRP
>A0A8I5YQQ6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pongo abelii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A673IPA5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSAELPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKITHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDEYLLEKHPLSQYKYIRSCITLGRLPHLMLVSKDSLYSQLPSS
GFMAPSYSRRTPQPSPCPGGGDPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDEQQIEEHANWKYRKCGYLEKATHSHTLSRLVCDSSISQADAEQLRTLCSR
DPLYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVHNLDIFLRWKNAVLQML
ETWLSKERLLSNSTPRFLTDDEELTEQPSSLRQCSRLLYAEVLCLIINTSVFSEFMMSPS
SPITETADWLMKLILHSDWLLQTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLE
ECRIMSSAKRPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQ
GLDLRMLPYGCLSIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIRDKNKG
EAYDRAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGY
KRERVPFVLTQDFLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLG
CGMPELQSFDDIAYLRKTLALEKNQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPN
EH
>A0A673IWE7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMRDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWDQWMEYNFTCDLEPCSVVAQS
GKSCSDKKIFVNVKFEGSEETFVLQQGPQDLPMFLKRNALRKKSTVFRSAKQEKPEDYTL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSINEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCIALYGVIEKTKKRPTKKKNKSSDCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGMNGEKTVATKEEMVGLLQKWPELPAIHALELLDYSFPDPHARSFT
IRCLRKLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMH
VSSVSLRFGLILEAFCRGSIFHIKNLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMK
VCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDTLGIIFKN
GDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRN
NSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECC
EQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKVRIAQTGIIYYP
>A0A673IBT0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
LCFSFVVCAMPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLL
LWKEAQTYPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGR
AERILDSKIGVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYS
MPLEAGSLENLIDKHEGVIKITMHYDQSQVCSVNLVCITELMDQALKKWQTTHGPEEDIG
FRSDYVLHVSGKLEFLFEDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIG
SVLARKTSNPPLPLPPKKRLPTASTLCFLIVCHVRAGLFHGTELLCKTAVSSESSSRSEH
VWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKPRSTKNTHLNKYQTIRKAGKVHYPIA
WVNTMVFDYRGQLKTGDIILHCWTSFPDELEEMLNPIGTIQTNPYTENATELHINFPEYS
TQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMERDPLSQLCENEKDLIW
TLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYV
REFAVYCLQDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERSQSSRKIGHFLFWHLR
SEMFMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFGTIKTKTKQAH
LKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGINVERCKYMDSKMKPLWIVYNNKLLEG
DTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSA
DTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGI
GDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTSNTE
KFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEA
LKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A444U5T4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acipenser ruthenus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQDETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVDLRDVNGPHSRALYVYPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKESLYTQLPID
NFTMPSYARRISTATPYMNGETSAKSLWTINDTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLKYDMYIPDIPRAARLGLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPEMSTIEEHANWTISRELGFNYCPTGLSNRLARDNELTESDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHILVNIPEILPKILLAVKWNSRDEASQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRLEECRIMS
SAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRM
LPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDLA
IDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVP
FVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPEL
QSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A673J2X5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMRDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGLCHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWDQWMEYNFTCDLEPCSVVA
QSGKSSPGYAFHIFTLKKSTVFRSAKQEKPEDYTLQINGRWEFIYGKYPLCQFKYIFTCL
HGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRAQSKPPPLPLKRVRRHFYTGTRSVIN
RGTTSLQSLSFSQLVVQAGLFHGSELLCKVVTSNEVSVCSEPVWDQKLVFDISVSDLPRM
SRLCIALYGVIEKTKKRPTKKKNKSSDCPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPDL
LNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKTLILTNGTVFFQHLKLREIVDN
KNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVGLLQKWPELPAI
HALELLDYSFPDPHARSFTIRCLRKLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLERA
LANKKIGHFLFWHLRSEMHVSSVSLRFGLILEAFCRGSIFHIKNLMKQNEALNKMKALND
FVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMK
PLWLMYKNKYDTLGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNK
TGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAG
YCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHV
IQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDS
LALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A8C4VH96|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gopherus evgoodei|TrEMBL
MELGNYEQPVVMREEAKRRRRRMKPHSPASNLSSVELISIEFILPTSNKQVQETMLLEIA
GNCTVEQMKAQIWMRAIEMSQTTDFYHKFAPDQFILQYQKKGQWYEIYDKHQVIQTLDCI
LYWKVLQKKVGKISVIQKQKPAQAVQEFQTQLNDLIGYDVTDVSNVHDDELEFTRRRLVT
PRMIEVACRDPKLYSMHPWITSKPLPEYVLKKITNNNIFIIIHRGTTSQKIKVSIDDTPD
MILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNGEE
IHLVLDDPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRKFR
VKIVGIDIPVLPRNTELTVFVEANIQHGQQLLSQRRTISKPFTEEVLWNTWVEFDIKIKD
LPKGALLNLQIYCGKAQALSTKVNLQSHDSPNSDSKCKTQLLYYVNILLIDHRSLLRSGE
YVLHMWKISGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSDPQ
GDRTRAEMPNQLRKQLEAIIDTDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWG
QQEIVAKTYQLLAKREAWDHSSLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVLHY
LLQLVQNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLHDFMKQVQIIKL
LHKVTMDIKSVSAEKYDVTSQVITQLKQKLEKLQNSKLPESFRVPYDPGLRAGALVIEKC
KVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWEAESLD
LCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEILNQWLKDRCVIEEKF
QAAVERFVYSCSGYCVATFVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGINKE
RVPFVLTPDFLFVMGTTGKKTSMHFSKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQ
LTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKH
SA
>A0A8C0UDB7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyanistes caeruleus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRYFCRIMSSAKRPLWL
NWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSI
GDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAY
IRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A4W6F9F3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRMRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A484CCB5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Perca flavescens|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLLSIKQQLFTEARKYPLYH
LLQEESSYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNLESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDCSPARSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLAYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDGEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMLKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFERSMPACPLHQLVPTCLSAPGCGMPELQKAYLSV
>U3JN97|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ficedula albicollis|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQDPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAIYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLRSGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3B4A2W8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Periophthalmus magnuspinnatus|TrEMBL
MPPGNGMQEEWEKEEAWDQGIMMDFLLPTGIFLKFPVSRNDTIKTIKKMVWKNARSEALF
SALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISL
LIGKGLHEFEAQKNHEVNEFRTKMRVFVEEKALERQLLPWHQWMEYSFPCDLEPCCCPPD
GGSNNKTKNTKKIFVNIKFESSDESFMLQQNPQDRPLCLVKSALKKKATVFRSIRQEPED
YTLQVNGRWDFIYGDHPLCQFKYIFNCLRNGQNPQLTMVHHSTITKYQEEQGRMCNQVFK
SRTLSRPPPLPLKKQNTSSLWSISEPFHIQLLQGSRVNADEGMKLVVQAGLFHGSELLCK
VVTSSEVTVCSEPLWDQKLEFDINVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADC
PIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFP
NIRPHPLYYPPLDKLLRLKEIMDNKNYTEFFEDEKELLWKLRYEVRDHYPESLSKLLLIT
KWSKREDVVQMVSLLGHWPDLPAIHALELLDYSFPDPAVRSFTIRCLKKLSDRELLQYLI
QLVQVLKYESYLDCDLTMFLLERALSNRKIGHFLFWHLRSEMHVSSVGLRFGLILEAYCR
GNIHHIRLLTKQNEALSKMKALSDFVKSGSQKMTAEDLKLCIKQESYVEALSDLLSPLNP
SIILNEICADKCRFMDSKMKPLWMMYRNSSVQGEMVGIIFKNGDDLRQDMLTLQMIHLME
NLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNW
LKSKNPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGN
FKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEWAYKILCRNGTLFVNLF
AMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSL
AKDNRP
>A0A669BI54|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDSEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRYPLSQQIWHYGGLLRTLFRANMYCLLKEWPSIRPEQAMELLDCNY
PDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHF
FFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDE
TQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLWLNWENP
DIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVG
LIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRSCAGYCV
ATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISK
GSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTL
ALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A669BN07|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MAPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLTTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYSKLDKGQIIVVIWVIVSPTNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPME
FFTMPSYARRISTATPYMNGETATKNLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLTYDMYIPEVPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHY
SSPVKFPDMSTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHDCINMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMVREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFESQWD
>A0A8C0X1K8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Castor canadensis|TrEMBL
MCFNFMMPSAMADILDIWAVDSQIASDGSVSVGFPLPTGIYIQLDVPREATISYIKQMLW
KLCDVRPFLPVLKLVTKDPEVNEFRRKCVNSQTYPPEHEPSLIVAVHFENSQDVFSFQVS
PDMNPIKINELAIQKRLTVHGREDEASPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMN
RTLPHFILVECCKIKKMYEQEMIAIEAAISRNSSNPPLPLPPKKTRVISHVWDNNNPFQI
VLVKGNKLNTEETVKAHVRAGLFHGTELLCKAIVSSETSGKNDHIWNEPLEFDINICDLP
RMARLCFAVYAVLDKVKTKKSTKAINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSG
DVILHSWSSFPESVNPMGTFRQPYTENATALHIKFPENKKHPYYYPPFDKIIEKAAEIAS
SDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSI
KWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVSCLRQMSDEELSQYLL
QLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCR
GSVGHMKVLSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQS
PLNPCVILSELYVEKCKYMDSKMKPLWLVYSNKVFGEDSVGVIFKNGDDLRQDMLTLQML
RLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDA
LLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGH
ILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLF
ITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWM
AHTVRKDYRS
>F1RB17|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Danio rerio|TrEMBL
MPPGVYGMQEVWEMEGRQHVNIEFLLPTGIYLNFTVACSDTISTIKKMLWKNAKNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFLPILRLVAREGDRVEKLITTQINQL
IGKGHHEFDSQKNHELNEFRTKMRAFCEEHAYLRQTLPWDKWMEYNFPCDLEPCSSVTQS
GKSRSIKKIFVNVKFEGSEETFVLQQDPQDLPVVLKRNALRKKSTVFRSVKQEKPEDYSL
QVNERWEFIYGKYPLCQFKYIFTCLHGGLTPHLTMVHYSSIVKYQEEQSGLSSQVSRSRA
QSKPPPLPLKRQNTCSLWSIQEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCFDPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGPNGEKVIATKEEHQKLKEIVDNKNSTEFFEDEKELLWKLREELRL
KYPESLPKLLLITKWNKHEDVAQMVGLLQKWPELPALHALELLDYSFPDPHVRFFTIRCL
RKLPDDKLFQYLLQLVQVLKYESYLDCDLTSFLLERALANKKIGHFLFWHLRSEMHVPSV
SLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSASQKATRIQTTEDMKVCIK
QETYMEALSDVVSPLSPSIILCELCADKCKFMDSKMKPLWLMYKSKYDSVGIIFKNGDDL
RQDMLTLQMIQIMDILWKTEGLDLRMQPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNS
AATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRES
GQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRVCCEQAY
KILCRNGTLFVNLFALMKAAGLPELNSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKVNWMMHTFAKDNR
>A0A6J0D379|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Peromyscus maniculatus bairdii|TrEMBL
MPPGVDCPMDFWTKEESQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEVAAHRQQLGWEDWLQYSFPLQLEPSARSWRA
SILRVTNRALLVNVKFEGSEESFTFQVSTNDMPLALMACALRKKATVFRRPLVEQPEDYA
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPAKKPSSVSLWSLEQPFCIELIEGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVICLPEVAP
HPVYFPALEKILELGRHGERGRVTEEELQLREILERRGSGELYEHEKDLVWKLRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQ
ETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A8C9Q5G4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Spermophilus dauricus|TrEMBL
MPLGIDWPMEFWTEVEKNRSVVVDFLLPTGIYLSFPVSRNANLSTIKQMLWHKAQNEPLF
HMLSDPKAYVFTCVNQTAEQQELEDEQQRLCDVRPFLPMLRLVTRQGDRMEKLINSQISL
LIGKGLHEFDCLQDPEVNDFRTKMCQFSEEAAAHRQQLGWEAWLQYSFPLQLEPSTRSWG
DSNTSQISNPDLLVNVKFEGSRESFTIQVSTKDVPLALMACALQKKAKVYQHLTMEQPED
YVLQVNGRHEYLYGSYLLCQFKYICSCLHSGQTPHLTMVHSSSILAMRDEQSRPAPQVQK
PHTKPPPIPMKKPSSVSLWSLGQPFCIELIQGSKINADEQMKLVVQAGLFHGNEMLCKTI
SSLEVSVCSEPMWKQHLEFDINICDLPRMARLCFALYAVMEKAKKAYSSKKKSKKEDCPI
AWANLMLFDYKDQLKTGELCLYMWPSVPGGPRPSRERLLEGEASRTGSPTTTSLLPSDEK
GDLVLNALELLDFSFPDCHVGSFAIRSLQKLTDDELFQCLLQLVQVLKYKSYLDCELTQF
LLDRALANRKIGHFLFWHLRYSEMHVPSVALRFGLIMEAYFRGSTHHMKVLMKQVEALSK
LKALSDFVKVSSQKTTKPQTKELMHLYMRQDTYLEALSHLQSPLDPSTMLAEVCVERCTF
MDSKMKPLWIMYSSEEAGSADSVGIIFKNGDDLRQDMLTLQMIQLMDALWKQEGLDLRMT
PYGCLPTGDCMGLIEAVQHSDTIANIQLNQSNLAAMAAFNKDALLNWLKSKNPGCPVSWS
YMPGPGASLPCPQLPEETSLCEACSVAALHSPQLFHIDFGHFLGNFKTKFGINRERVPFI
LTHDFVHVIQQGKTSDNEKFERFRGYCEQAYSILQRHGLLFLQLFTLMQAAGLPELSSSK
DIQYLKDTLALGKTEEEGLKHFRVKFNEALRESWKTKVNWLAHNLTKDNRQ
>A0A5F8HDP2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodelphis domestica|TrEMBL
MPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISHIKQMLWKQAHSY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKVVTRNCDPGEKLDSKI
GVLIGKGLHEFDALEDPEVMEFRSKMRQFSEEKIQSLIGLSWMDWLKHTYPPEQEPSIPE
NLEDKLYGGNLVVAVHFENCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEVDPYDY
VLQVSGRLEYVFGDHPLIQFQNVWENTQPFQIVLVKGTKLNTEETVKVHVRAGLFHGTEL
LCKPVVSSEISGRNDHVWSEPLEFDINICDLPRMARLCFAVYAVDKVKTKKIFSLIVIDE
LEEMLNPMGTVQTNPYTENATALHIKFPENKKQPYYYPPFDKVREALELLDFNYPDQYVR
EYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLDRALANRRIGQFLFWHLRS
EVHIPAFSVQFGVILEAYCRGSVGYMKVLSKQVEALNKLKTLNSLIKLNAMKLNKAKGRE
AMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLRIVYNNKVFGGDPV
GVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETI
ADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDR
HSDNIMVRKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFG
RFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKVRTKFYS
>A0A455BH09|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Physeter macrocephalus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3P9APW5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPRPSSGELWGMHLMPPTIQVDCLLPNGMILTLECTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPVD
TFAMPSYARRISTATPYMNGETAAKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANWNISRELGFNYSHSGLSNRVARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVSIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERYGILCLYLEGFSTNSMQPLPCLCHGASWLHWNVLE
>A0A3Q3KKQ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monopterus albus|TrEMBL
MPPGKYGMQEEWEKKGDQEIMMDFLLPTGIFLKFPVSRNDTIKNIKKLVWKNARSEALFS
ALGDPDAYVFTCINQTAEREDLEEESRRISDVQPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRSKMRTFCEEKAQERQKWPWYLWLKYSFPCDLEPCCSLPST
NSKNTKKIFVNIKFEACDESFMLQQDPQDLPVVLMKSALKKKATVFRSVRQEPKDYTLQV
NGMWDFIYGNHPLCQFKYIFSCLRNGQNPHLIMVHHSTISKYQEEQGICNQVYKSRSLSR
PPPLPLKKLVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQKLEFDINVADLPRMSRLCF
ALYAVIEKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDEKSDL
LNPMGTVEKNPNVDSAAGLLIRFPNIRPYPLYYPPLDKVSEIERNGDISIATKEEYIKLK
EIMDNKNYTEFFEDEKELLWKLRAEVCNHYPESLSKLLLITKWNKREDVVQMMSLLRSWP
DLPAIHALELLDYSFPDPAVRSFTVKCLRKLSDDELLQCLIQLVQVLKYESYLECDLTTF
LLERALSNKRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIRGLTKQNEALGKM
KALSDFVKSGSQKMTAEDLKLCIRQESYLEALSDLLSPLNPSIILAEICADKCRFMDSKM
KPLWLMYKSPWAQRDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRDKLDQAIE
EFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFI
LTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRSGMLFVNLFAMMKAAGLPELTSFK
DIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A7K6N707|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pedionomus torquatus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCSSSNLSSMELISIEFILPTSNKNTKVPEMVLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIRDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIGTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDICVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3Q2ZNX8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Kryptolebias marmoratus|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFMEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMLKDPEVQDFRRSILSVCREAVEEREGGGAHSQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
SFVPPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVLFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDNSVSAADAEQLRSLCAKDP
LYELSEQEKDFLWRHRHYCINMPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQSLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGETYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A8D0DH05|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salvator merianae|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCLPNGMMVTLECLREATLLGIKHDLFKEARKYPLFH
LLQEESSYIFVGVTQEAEREEFFDESRRLCDLRLFQPILKAIEPVGNREEKILNREIGFA
IGMPICEFELVKEPEVQEFRRNILSVCREAVETRGSAGPQSQALYVYPPNVESSPELPKH
VYNKLDKGRIIVTIWVIVSPNNDKQKYTLKIPHDALPEQVIAEAIRKKTRSMHLSPEQLR
LCVQEYQGKYLLKVCGCDEYFLEKYPLSQYKYMRNCITIGRLPHLMLMSRESLYSQLPAN
VFVLPSYARRSAATSHVNGDVPTKSLWSINSLLRIKILCATYVNVNIRDIDKIYVRTGIF
HGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDLPRAARLCVSICSVKGRKGAKEEHCP
LAWGNVNLFDYKDTLVTGKMALNLWPVPHGLEDLLNPIGVGGSNPNKETPCLELEFTWYS
HTVKFADSAEIEEHANWAMSRELGLNYXMVGLSNRLARDSSLDESELEQLRNISNRDPLS
EITEQEKDFLWRHRHYCVNIPETLPKLLLSVKWXSRDEVAQMYCLLREWPLIRPELSMEL
LDCNFPDPVVREFALKCLVKGLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLTKKALTNQ
RIGHFYFWHLKSEMHSKPVSQRFGLMLEAFCRGCGMYLKHLNRQVEAMEKLINLTDILKQ
EKKDETQKMQMKFLVEQMRRPDYMEALQGFICPLNPVHQLGNLRLDECRIMSSAKRPLWL
NWENPDIMSELLFTNHEIIFKNGDDLRQDMLTLQIIRIMESMWQNQGLDLRMLPYGCLSI
GDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNALHHWLKDKNKGECYDAAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGVQECTKTKEFERFQEMCYKAYLTIRQHANLLINLFSMMLGSGMPELQSFDDVAY
LRKTLALDKTEQEALEYFTKQMNEAHHGGWTTKMDWIFHTIRHMPLSEASHD
>A0A8D0BW54|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salvator merianae|TrEMBL
MPPGIYCPVEFWSKEANRNIQVDFLLPTGIYLNLLVPCSATLSTIKKAVWHHAQYEPLFH
MLSDPDSYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSSGDPEVNDFRAKIHQFCAERAAQRQQLSWRAWMEYSFPVQLEPLAGSPER
KNSLRIPNKNIFVNVKFESGGESFTFHISPKELPMTLMSYAVKKQATVFRHQRINSPEDY
TLQVNGKCEYLYGNYPLYQFQYIHDCLHHGLLPHLTMVHSSSIMALWEEQANGIAHSPKS
VARPPPIPKKKPTSASLWSFDQPYYIDLVQGSKVNADERMKLVVQAGLYHGNEMLCKMVS
SSEVSVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIA
WVNVMLFDYKDQLKTGECSLPMWSSFPDEKGELLNPMGTVQTNPNTESAAALVIHFPSLS
AYPLFICHHGMVHLLQSWRELPVLNALELLDFNFPDRCVSSFTVNSLKKLTDVELLQYLL
QLVQVLKYESYLDCDLTKFLLDRALSNRKIGHFLFWHLRSEMHVPSVAIKFGLILEAYCR
GSPYHMKALMKQSEALSKMKALNDIVKLSSQKISKLQTKEYMHACMRQETYMEALSNIQS
PLNPHIILSKVSVELCTFMDSKMKPLWIVFSNKNMGGSNMGLIFKNGDDLRQDMLTLQMI
HLMDILWKKEGLDLRMTPYGCLSTGDKMGLIEAVMDSDTIANIQLNKSNMAATAAFNKDA
LLNWLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGH
FLGNFKTKFGINRERVPFILTYDFVHVVQQGKTNNSEKFERFRDYCERAYMILRSHGLLF
LHLFALMKAAGLPELSCSKDIQYLKVTGGNN
>A0A8C6XAR2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Naja naja|TrEMBL
MPPRPSSGELWGMHLMPPKILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVELRDANAPHSRALYVCPPNIESSDLPKHI
YNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLKL
CVLEYQGKYILKVCGCDEYLLEKHPLSQYKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRW
NEWLKYELFVFDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINMFDYTDTLVSGKMAL
NLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSPVKFPDMSVIEEHANWIISRE
QGFNYNHAGLSNRIARDNELRDNDKEQLRAICTRDPLSEITEQEKDFLWSHRHYCVSMPE
ILPKLLLSVKWNSRDEVAQMYCLIKDWPQIRPEQAMELLDCNYPDPMVRAFAIRCLEKYL
TDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKNVSQR
FGLLLDSYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPD
FMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKN
GDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCK
GGLKGALQFNSHTLHQWLKDKNKGEMYDPAIDLFTRSCAGYCVATFILGIGDRHNSNIMV
KDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEM
CYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQM
NDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K9LE87|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhabdornis inornatus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEDKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIRKQATVFRHETLQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAILAMRDEQNNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWRQRLEFDISVSDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLHALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEEAGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A060Y027|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MPPRPSSGELWGMHLMPPSIQVDCLLPNGMILTLVCTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEVSS
PSCLPVPGT
>A0A8C2XMQ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MNIFYLFIIHILIGSPRSRVMFAVSHVYQWKHSLWLCSAEALHPNSSSPPFQLLWKQAQS
FPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRAERLLDS
KIGVLISKGLHELDAINDQEVKDFRSKMFRLSEERMQQVQMMTCTEWLQACFSPQLEPPA
GTAITDGLNDRPADLKIIIHFDQSQVRVCSPGGETCIVPSSCVPSELMELALKKWLTTHG
PEEEEAWRGQYVLRVSHCLEFLCGDQPLIQYKYIRTCMQAKESPRLTLVHTSTVKAMFDK
EISTIGAVVGRKSSNPPLPLPPKRRVPTVSSVISFKIVLVNGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESSGRSDHTWKDSTLEFDLSVCDLPRMTRLCFAIYAVMDKVKKQKST
KNHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATSLH
INFPEYSSHSIVFPPFDKGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCRENF
PQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLEE
ELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFAL
ILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKTARSKTKEAMLTKEAMMTCLR
QSGYSETLSDLHSPLNPNVLLSGINVERCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNG
DDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTS
SNVAAAAAFNKDALLNWLKERNSGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMV
RSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCE
EAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEDALKQFRQKFDE
ALRESWTTKVNWMAHNVAKDNRS
>A0A8C2XBB4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MPSGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNASSEALFG
ALGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRMFCEEKAQERQMLPWQQWMKYSFPCDLEPCCSPPDG
CLLLALMCLSQESFMLQQDPQDLPVALMRSALKKKATVFRSLRQEPEDYTLQVNGRWDFI
YGKHPMCQFKYIFSCLRNGQNPYLTMVHHSTIHKYQEDQGSMYNQVYKSRSLSRPPPLPL
KKNTSSLWCISEPFYIHLLQGSRVNAGEGMKLVVQAGLFHGSELLCKVVTTSEVTVCSEP
LWDQKLEFDINVADLPRMSRLCFALYAVLEKAKKPRGTKKKNKKADCPIAWVNTMVFDYK
DQLKTGEFLLSTWPSVPDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPLDK
EVRLYISHCLILTQLKYMKLKEIMDNKNSTEFFEDEKELLWKLRTEVRDHFHESLSKLLL
ITKWNRHEDVVQLVSLLKNWRDLPGIHALELLDYSFPDPAVRSFTIRCLRKLSDNELLQY
LIQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLRSEIHVASVSLRFGLILEAY
CRGNIHHIRLLTKQNEALGKMKALSDFVKSGSQKMTADDLKLCIRQESYLEALSDLLSPL
NPSIILAEICADKCRFMDSKMKPLWLMYNPGAQEDMVGIIFKKGDDLRQDMLTLQMIQLM
ENLWKKEGLDLRDKLDPAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFG
HFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNATL
FVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNW
MMHSLAKDNRP
>A0A8C7SKP1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MVWRNASSEPLYGALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGD
RVEKLTNTQISLLIGKGLHEFDSQKNHEVNEFRTKMRSFCEEKAQDRQRLPWYQWMEYSF
SCDLEPCVSLAEPGGIKTKGTKKIFVNVKFEASDVSQEPQDLPVILMRSALKKKATVFRS
VRQEKPEDYTLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQG
CLGSQVSKSRSLSKPPPLPVKKSLMWVLIICVCVCVRACACVYARVCVSQLVVQAGLFHG
SELLCKVVTSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPQSQSME
DCPLAWVNTMVFDYKDQLKTGEFLLSTWPSVPGDLLNPMGTVEKNPNVDSAAGLLIRFPN
IRPHPLYYPHFDKVHLILHTRFNSYSHQGRGKGLSILKEIVDNKNYTEFFEDEKELLWKL
RGVVRERYPESLSKLLLITKWNKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRS
FTIRCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSE
MHVSSVSLRFGLILEAYCRGNIYHIKSLCKQNEALNKMKALNDFVKSGWQKTSRQQMTDD
MKLCIKQEAYMEALSYLLSPLNPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDTVG
IIFKNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIA
NIQRNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRH
NDNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFER
FRECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNF
KVKFNEALRESWKTKVNWMMHSLAKDSRL
>A0A8C7SLU1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MVWRNASSEPLYGALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGD
RVEKLTNTQISLLIGKGLHEFDSQKNHEVNEFRTKMRSFCEEKAQDRQRLPWYQWMEYSF
SCDLEPCVSLAEPGGIKTKGTKKIFVNVKFEASDVSAFNDIFDWKIQNFYQCIDQVKIWR
MTLGIKNFKKLRQEKPEDYTLQVNGRWEFIYGKYPLCQFKVSKHNNTTHVLFLSYYQQNT
SSLWSIEEPFHIHLLQGYRVNADEGMKVGVAGLFHGSELLCKVVTSGEVNVCSEPLWDQK
LVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPLAWVNTMVFDYKDQLKT
GEFLLSTWPSVPGDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPHFDKVIATKVE
VRDSLLFFFEDEKELLWKLRGVVRERYPESLSKLLLITKWNKHEDVAQMVAFLQKWPDLP
ALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLE
RALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGNIYHIKSLCKQNEALNKMKAL
NDFVKSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLLSPLNPSIMLSEICADRCKFMDSK
MKPLWLMYKNKWVQGDTVGIIFKNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCL
STGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFT
LSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTY
DFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQ
YLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDSRL
>A0A8C9SF29|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLISIKQQLFAEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAMEEREGGGAHSQALYVYPPNVESSPDLPQH
IFCKLDKGRLIVTIWVIVSPSNAKQKYTLKIAHDCLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIVVGRLPHLMLVSKDSLYSQLPAS
GFVAPSYSRRTPQPSPCPGGGDPSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTELPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDTLVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVIFPDEQQIEEHANWVISRELGYNYCPGLSSRLACDSTVSQVDVEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLRDWPLMQPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMEKLVNLTDTL
KQEKKDETQKMQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A7K9IBA7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bucco capensis|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVESPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSTIIAMREEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALLICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPRALAKLLIITKWNKHEDVAQMLSLLQSWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGRGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3N0ZB66|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabarilius grahami|TrEMBL
MPPAKTDQLDLWAESGMDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERLLDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKRISEEKMHQMQMMSWREWLRSCYSPQLETGLLE
NLIEKHEGVIKITMHYDQSQDTASLKVSLHCTVSELMDQALKKWQTTHGPEEDIGARSDY
VLRVSSKLEFLFEDHPLSQYKYIRACLLANENPHLTMVHCSIVKAMFEKEISTIGSVLAR
KTSNPPLPLPPKKRQPTQLHTCVWKVHSVFRINLVKGNKVNADDAAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNPQSK
YQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPY
TENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGSSDLMTMGRGGKKFYIELKEIMER
DPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPR
DALELLDFNYPDQFVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERA
QTSRKIGHFLFWHLRQVEALSKLKAVNELIKLATIKTKAKQAHLKEAMMTCLRQTGFIET
LSDLHSPLNPNVLLAGVNVERCKYMDSKMKPLWIVYNNKLLGGDTVDIIFKNGDDLRQDM
LTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAA
AFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLF
HIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGKQYCEEAYLILRKN
GNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTK
VNWMAHIVAHPS
>A0A7J8A0A7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myotis myotis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWGINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLEMEFDWF
SSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDP
LSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAM
ELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDIL
KQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7L2NZG8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pycnonotus jocosus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLDTIKQVLWKQAQYEPLFH
MLSDPDAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSDFRSKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVRFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKVA
CKPPPLPKKKPNYGSLWSLEQPFSIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVAVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C2TMF9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coturnix japonica|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGAIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLSHTPVKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQVNGSEPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADE
RMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAV
IEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMG
TVQCNPNTESAAALVICFPNAASHPVYYPSFEQVGNTDVFLRGFLVQDRISILPPTSIFH
STPLLLHLSGLNKPFGLRLSPLYALCCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMR
YDIRDQYPQALAKLLTITKWNKHEDVAQVRMLELATWPELPVLNALELLDFSFPDRYVGS
FAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSE
MHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEM
MHVCMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVG
IIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIA
NIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFER
FRGYCEKAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHF
RLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L2YB35|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Jacana jacana|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMA
VKPPPLPKKKPNYGSLWSLEQPFHIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAL
HPVYYPSFEQLLELGRNGDQPRAVPDDPEEKLQLKEILERRNHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHV
CMKQETYIEALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A5C6PDQ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu flavidus|TrEMBL
MPPAMTDLLDIWATHAPLAGHDPDQITMDFLLPTGIYIQCDVPRVATIKEIKQLLWKEAH
SFPMFSKLGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRGERLLD
SKIGVLIGKGERGEGNHWMLPDVFVTCHCVPPSSSSSSSSSSLCGLSTSPEAIKSLHELS
AINDQEVKDFRSQLLLQLDVPADTTTMDGTDRPADLKVIIHFDQSLDSASLKMASTCTPR
DLITQAVRKWLTTHGPEEDALRGQYVLRVSHCLEFLCGDHPLIQYKYIRTCMQAKEPPHV
TLVHNNTIKTMFERDICAIRAALTPKSCSLPLPLPPKKRAPTQVQTCVWDVSSPFKIVLV
NASKVNAEETAKVQVRAGLFHGTELLCKPAVSSESSGRSDHAWKDTTLEFELPVCDLPRM
TRLCFAIYAVMDKVKKQKSTKNTHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDI
ILHCWSSFPDELEEMLNPIGTIQTNPYTENATALHISFPEYSSHPIIFPLFDKLSLFQIL
EKAAEIAGASDCASMGRGGKKFHIELKEIMERDALSQLCENEKDLIWTLRYDCRENFPQS
LPKLLLSVKWSKHEDMAQLQALLQIWPRLCPRDALELLDFNYPDQYVREYAVNCLRDMSN
DELSQYLLQLVQVLRYEPYYDCALTHFLLERAQSSRKIGHFLFWHLRSEIHMPAVSVQFS
LILEAYCRGSIPHIEVLKKQVEALNKLKAVNELIKLGTLKNARSKTKEAMLTKEAMMTCL
RQTGFSETLSDLHSPLNPNILLSGINVEKCRYMDSKMKPLWIVYNNKLLVGDMLGIIFKN
GDDLRQDMLTLQILRLMDRLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLT
SSNMAAAAAFNKDALLNWIKERNSGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRSNGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGQAEKFGSFRQYC
EKAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSDDEALKQFRQKFD
EALRESWTTKVNWMAHNVAKDNRS
>A0A401P0A6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scyliorhinus torazame|TrEMBL
MIKLGYRSFSLKEPYGYSQISADHCITADFLLPTGMYIQLEVPREATIEQIKSLLWRQAQ
TYPLYSILGEQDSYMFQCVNQSAVHEELEDESRRLCDVRPFLPVLKLVARNCNRSEKLLD
SKIGVLIGKGLHEFDALTDPEVKEFRSKMRKINEENMLKRQGHSWMDWLQHNFPPEIEST
GFNHAEDKLHKDNFLIAIRFESCQDIFNFQVSPDFNPLNLNELAIRKQLTNHGKDNEEFN
PRDFVLRVSGKQEYVFGDQPLIQFRYIRNCVLNGIHPQLTLVDCSTIKEMCDHEMSAIGI
ALHRKLSIAPLPLPPKKRAISRVPGNVWDINTPFKIVLARGNKINADEALRVQVWAGIFH
GTELLCKPVVSSEISGKNDLTWNETLDFEINICDLPRMSRLCFVVYGVMDKVKKQKSTKN
VAKFQTIRKAGKVHYPIAWVNTMVFDFRGQLKSGDLSLHCWSSFPDELEEMLNPMGTTQT
NPYTENATDLHIQFHEYSKSAIFYPAFDKGRGWKKLHIELREITERDPLSQLCENEMDLI
WTLRYDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWTKLAPREALELLDFNYPDQY
VREYAVGCLKEMSDEELSQYLLQLVQVLKYEPYFDCALSRFLLERAQANRRIGHFLFWHL
RSEMHLPATSLQFGLILESYCRGSITHIKELSKQMDALSKMKAVNNLVKLSSLKVAKHKM
KDVIHACLKQPVYKEALSNIQSPLNPSIILSELNVDKCRYMDSKMKPLWILYNNKMSGGE
PVGLIFKNGDDLRQDMLALQILHLMDMIWKEAGLDLRIVPYGCLATGDKSGVIQVVSAAE
TIANIQLTNSNAATAAFHKDALLNWLKEKNSADALERVIEEFTLSCAGYCVATYVLGIGD
RHSDNIMVRESGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKF
NRFRHCCEEAYLILRKNGNLFITLFALMLTAGLPELGSIKDIQYLKDSLALGKSDDEALK
QFRQKFDEALRESWTTKVNWMAHIVAKDKGS
>A0A670YMN2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pseudonaja textilis|TrEMBL
MPPGMYCPSEFWSKESNYTIHVDFLLPTGIYLPLPVSCHASLAAIKKVVWHQAQYEPFFQ
MLSAPDSYVFTCINQAAELQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLLNSQISLL
IGKGLHEFDSLADPEVNDFRVQMQDYCEQKAAQRQQLSWKDWMEYSFPVQLEPALSGLGR
RPSLPMPGKTIFVNVKFQSGGESFTFQISLKEFPITLMSYAVKKQATIFRHQRVSPADEY
TLQVNGKYEYIYGEYPLYQFQYIRECLHRRFVPHLIMVHRSSLLTLREEQSNGLGHPPKT
ALKLSPGPKQKLVVQAGLYHGHEMLCKMMTSTEANVCSEPTWDQTLKFDIHVCDLPRMAR
LCLVLYSVVEKAKKARSTKKKSKKADCPLAWVNVMLFDYQDQLKAGECVLPMWSAFPDEK
GELLNPTGTIQTNPNAESAATLFIRFPGISLYPIYYPSMRQILEKGQNGHCACGTGEDPE
EQLKEILERRSCIELYEHEKDLVWKMRYQIRDQYPGALAKLLMVTKWNKHEDVAQMIFLL
QSWPELPVLNALELLDFNFPDPHVSRFTVNSLKKLTDAELFQYLLQLVQVLKYQSYLDCE
LTKFLLGRALSNRKIGHFLFWHLRSEMHFPSLALRFGLILEAYCRGNADHIKALMKQSEA
LNKLKALNDLIKVSAQKNTKPQTKEFMHTCMRQETYLEALSHLQSPLDPRIFLARVSVEL
CTVMDSKMKPLWIMFNNGEAGGPNTGLIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLR
MTPYGCLSTGDKMGLIEVVMNSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALE
QAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRENGQLFHIDFGHFLGNFKTKFGINRER
VPFILTYDFVHVIQQGKTSNSEKFERFRDYCERAYMILRGHGLLFLHLFSLMKAAGLPEL
SCSKDIQYLKDSLALGKTDEEARKQFHLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A673CTV4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQQSREEFYDETRRLCDLRLFQEENILNRELVRGFAIGMPVCEFDLV
KDPRCQRSHSRALYVYPPNVESTQELPKHIYSKLDKGQIIVVIWVIVIAEAIRKTTRSML
LSPEQLKMCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSL
YTQLPTDNFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDK
IYVRTGIYHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRK
GAKEEHCPLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCL
ELEFDHFSSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTDSDTEQLRQ
LSNRDPLSEITEQEKDFLWRHRHYCMNIPEIPKILLAVKWNSRDEVAQMYCLLKEWPSIR
PEQAMELLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLL
KKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLIN
LTDILKQEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSS
AKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRML
PYGCLSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAV
DLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPF
VLTQDFLIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQ
SFDDIAYIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A673BFY8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLLSIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVHLCT
>A0A822GSM9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ranitomeya imitator|TrEMBL
MCFRSIMPPAMADTLDIWAVDSQIASDGSISVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEDKIQSLVGLSWIDWLKHTYPPEH
EPSVLENLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEEE
ASPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSSLPLPLPPKKTRVISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQ
TNPYAENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASGDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALDNRRIGQFLFWHLRSEVHTPAVSIQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCRYMD
SKMKPLWLVYSNRAFGEDAVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A670Z5E7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pseudonaja textilis|TrEMBL
MELETSDQAVVMRDDNKRRRRRRMKPYCTANTLSSTELISIEFVFPTTSIVLDVPTNCTV
EQMKAQVWMRAVEGHQTSDLFRKIMPDQFLLLYQKKGQWYEIYDKHQIIQTLDCILYWKV
LQKKVGKIHVVEKPNPSDEVQDFQNQLNYLIGYDVTDVSNVHDDELEFARRRLVTPRTIE
VSCRDPKLYSMSPWTTSKPLPEYLLSRIANSNIFINIHRGTTSQKIKVAVDDTPDVILQS
FFTKMAKKKSLMNIPEDYSEQDFVLRVSGRDEYIVGETPIKNFHWIRQCLKKGDEIHLVL
DEPPDSNQDEVQKEEWPLVDDCTGVSGYHEQLTIHGKDHERVFTISLWDCNRKFRVKIIG
IDIPILPRNTDLTVFVEVNIQHGQQLLSQRRTTAKPFTEEVLWNVWLEFDIKIKDLPKGA
LLTLQIYCGKTPLPSAKGNLHPQDSPSTDPKYKTQLLYYVNLLVIDHRSLLRTGDYVLHM
WKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHKIASDPPEGRAR
VEMPNQLRKQLEEIIATDLLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWGEQKLV
AETYQLLAKREAWDQSALDVGLPIQLLDCNFSDETVRTMAVQKLEGLEDDDVLHYLLQLV
QAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGC
GKAMLKDFLRQVQVTELLHKVTREIKAISAEKYDVTPQVIAQLKQKLERLQDNKFPECFR
VPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTSLSSETIGIIFKHGDDLRQDMLI
LQILRIMASIWEEESLDLCLLPYGCISTGNKIGMIEIVKDANTIAKIQQSTVGNTGAFKD
ETLNQWLKDKCVIEEKFQSAVERFVYSCAGYCVATFVLGIGDRHNDNIMITGSGNLFHID
FGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLRFQNFQDICVRAYLALRKHT
NLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKHEEDAKKYFLDQIEVCRDKGWTVQF
NWFLHLVLGIKQGVEKHSA
>A0A822I8J2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ranitomeya imitator|TrEMBL
MPPGVDCPMEFWTKEESQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLHVSNRPLLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVERPEEYA
LQVNGRHEYLYGSYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
VKPPPIPAKKPSSVSLWSLEQPFCIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDISICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELMNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGRITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKASSQKTTKPQTKEMMHMCMR
QETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEKAGGAGSVGIIFKN
GDDLRQDMLTLQMIQLMDFLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8B9TNQ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A821YKY5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ranitomeya imitator|TrEMBL
MELESYEQPVVLRDENKRRRRKMRPHSAAASNIFSMEAIPIEFILPTSQKNSKVQDTILL
EIAGNCTVEQMKAQVWMSAIEKSHNSDFYHRLAPDQFLLQYQKKGQWYEIYDKHQVIQTL
DCIVYWKVLQKTVGKIHIIQKEKPSEETMEYQKQLNYLIGYDVTDVSNVHDDELEFTRRR
LVTPRMIELVKRDPRLYSMDPWVTSITLPEYLSKRLSSNNIFIIIHKGMTSHTIRVSIDD
TPDVILQSFFAKMAKKKSLLDISEEHSELDFVFRVCGRDEYIIGNAPLKDFHYIRQCIKN
GDEIHFVLDVPPDPSEDKVQKEEWPLVDDCTGVTGFHEQLTIDGKDHEKIFTISLWDCNR
KFRIKIIGIDIPVLPRNTELIVFVEANILHGQQVLSQKRTSCKPFTEEVLWNTWLEFDIK
IKDIPKGALLNLQIFCCKAQTATGKANIQSPDSTSSDPKFKNQLLYYVNLLLIDHRFLLR
QGEFVLHMWRIPGKGEDQGSINADKLTSATNPDKDTSMAISISLDKYCHPVALPKHKSVS
DPELDRARSEMPNQLRKQLEEILSTDPLHPLTPEDKELLWHFRYEVMKNPDAYPKLLSSV
KWGQQAMVAKTYQLLNKRDAWDDCSLDVGLTIQLLDCNFSDENVRAMAVQKLESLQDDDV
LHYLLQLVQVILFISASQFLNTGFHFHNHN
>A0A2Y9RT97|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Trichechus manatus latirostris|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLV
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWEAWLQYSFPLQLEPAARGWGT
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVERPEDYA
LQVNGKYEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPTPQVQKLR
TKPPPIPVKKPSSASLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVSVCSGPVWNQRLEFDINICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEQCLYMWPFVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
HPVYYPALEKILELGRHGEHGRFTEEELQLREILERRGSGELYEHEKDLVWKMRHEVQEY
FPEALARLLLVTKWNKHEDVAQMLCLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHVCMRQ
ETYLEALSHLQSPLDPSTLLADVCVEQCTFMDSKMKPLWIMYSNEEAGSEGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCE
KAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A2Y9RU22|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Trichechus manatus latirostris|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLV
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWEAWLQYSFPLQLEPAARGWGT
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVERPEDYA
LQVNGKYEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPTPQVQKLR
TKPPPIPVKKPSSASLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVSVCSGPVWNQRLEFDINICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEQCLYMWPFVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
HPVYYPALEKILELGRHGEHGRFTEEELQLREILERRGSGELYEHEKDLVWKMRHEVQEY
FPEALARLLLVTKWNKHEDVAQMLCLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHVCMRQ
ETYLEALSHLQSPLDPSTLLADVCSVEQCTFMDSKMKPLWIMYSNEEAGSEGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
EKAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q1HB39|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MDRKQIQVSDEEPVVLREEIRRRRRKKAITSSSSISMDQITVEFVLPTATWGSNPDSLQL
EVAGNWTVEQVKAQVWLKAVTSNLCPEFYQRFSPDHCILLYQKKGNLCEIYDKHQVFQTL
DCIRYWRALKKDVGKIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRRIELCDRDPKLYSMDPWVTRKPLPEHLLSKVSNGHILVVIHMSTASHTIKVSIDD
TPAQVLASFFNKTANKRVLLGIPDNVCETDYVLRVCGREEYLYGDKPLQNFNWIRQCLKN
GEEIHLVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNR
KFRVKVLGIDIPTLPKVPEFVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIK
IKDLPKGARLSLQVVCGKQPQTPNSKGSSYQDNTAGGGSHDGKTKSRLLYYVNLLLIDHR
SLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKESSMAIAILLDKYCYPVVLPK
SRDVGRDVGAVGEESEGGERGQREMPNHLKKQFEAIVTTDPLHPLSPEDKELLWHFRHEC
MRDPRAYPKLLGSVKWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRS
MAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGEAMLQDFRKQVEMTEALQKVTREIKTMSADKYDVTAQ
VVFQLRQKLEILQSSGLPDNFRVPYDPGLRAGALMIEQCKVMASKKKPLWLQFKKADPTT
LSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIV
KDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEEKFQQAVERFLYSCGGYCVATYVL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKS
SPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSED
EAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A7L1F4D6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sylvia borin|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEILLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDHFILQYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVEEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6J2BID5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zalophus californianus|TrEMBL
MWLSTRFRQNLFQVMSGMELKHHEQPVVLREDNGRRRRRMKPRSSAASLSSMELIPIEFV
LPTSQRNSKTPETALLHVAGHGNVEQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQKK
GQWYEIYDKHQVVQTLDCLRYWQVLHRSPGQIHVVQRRAPSEETLAFQRQLTALIGYDVT
DVSNVHDNELEFTRRRLVTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFII
IHRSTTSQTIKVSADDTPGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVG
ETPIKNFQWVRHCLKNGEEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHG
KDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKP
FTEEVLWNVWLEFSIKIKDLPRGALLNLQIYCSKAPALSGKASAETPGSESKGKAQLLYY
VNLLLIDHRFLLRHGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNY
CHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESL
KHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAI
AVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEI
AQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQV
ISQLKQKLENLQNSSLPESFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTAL
SNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVK
DATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLG
IGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTS
LYFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEE
AKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A6J2VTT1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chanos chanos|TrEMBL
MPPAMTDQLDMWADSGLDGDDQVLVDFLLPTGIYIQMEVPRESTIQHIKLLLWKQAQEYP
FFSLLGEMEGHMFECVNQAAVHEELEDESRRLCDVRPFLPVLKLITRNCGRAERLLDSKI
GVLIGKGLHELDALQDPEVKDFRLKMQRMSEEKMQHAQMMSWREWLMSYFSPPLEAGPVN
GLIDKAETIKIIMHYDQSQDTASLKVSVSCTVMELMEVAYRKWLTTHGPEEDGSYLGDYV
LRVSSKLEFLFGEQALVQYKYIRSCLLAQECPHLTLVHCSVVKSMFEREMSVIGAVLPRK
SSNPPLPLPPKKRGQSMQLQQQTCVWDVHTPFRITLVKGIKVNAEETAKVQVRAGLFHGT
ELLCKPAVSSESSGRTEHVWNRMMEFDIPVCDLPRMTRLCFAIYAVMDKVKKQKSTKNTH
LNKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHTWSSFPDELEEMLNPIGTVQT
NPYTENATALHFSFPEYSSYPVIFPPFDKILEKAADIAGSSDSVPMGRGGKKFHIELKEI
MERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWNKHEDMAQLQALLQIWPKL
SPRDALELLDFNYPDQYVREYAVNCLRDMSDEELSQYLLQLVQVLRYEPYYDCALSRFLL
ERAQNNRKIGHFLFWHLRSEIHMPAVCVQFALILEAYCRGSIPHIEVLKKQVEALSKLKA
VNELIKLGTIKAKTKTKELKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGVHVEKCRYM
DSKMKPLWIVYHNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPY
GCLATGDRSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKEKNSGDALEKAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFI
LTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVK
DIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAHRS
>H2YGB2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ciona savignyi|TrEMBL
WGYHNSLNVSVDFFLPTGIYIPLDIPRNYTIKQVKHVLWEEAIHYPLFSKLLNPESYIFT
YITSFGLTEEIVDELRHLSEVRIDFHWSTPLVGYQIVTMKKLMSAEILLNISDDNELNID
HESSSFRKDMREMAIQVSKQRDALHWKELIQQHFPPTIIPYLNDSTHYLKDFGLIQLTVE
NKVMYTIKINPGWTTDTLTREALAAWRQKTKSRLPSDNDDDYVLKGGGKEYLVGNHPIYM
FKNNLAPPVPEKHRPVWSLWQLDVMFKLRVIRAGNVNAAQERDKKLVIHIGLYHGSETLC
PTTYTKEPVKETAAGNEYQWDEECFFDINAVNLPRNAMLCFAVCSSKRGVGGKTKKDKKK
YIQAATPIAWVNMMVFDFKRFLKAGLYRLNCWPVNLDNLDSNNLFPRGGLMTNPDVEQAT
FIEIAMTEYQAAIMYPSLPEVRVLLLTFTWPNWLTGAFYIHISHLAHCCNLTWHIQPDKE
AARQAVVRESNLMTSAASKLHMTQLEEVIRKDRFDDLYDDDKSLLWRLRIDCREHFPDAL
SKVLASANWSSYKSVAMVQAMLNSWKPLSPEHAMELLDSQYADEHVRDFAVKCLESLRDD
ELQQYLMQLVQVLKFDSYLSSSLVRFILRRAWNNRKIGHFLFWHLKSEISQKTLNLRFSL
ILEAYLYGNLPHMKTLCKQHEALNKMRTLNDRVSFSPKDIKVRARQALKDTANQDSFREA
LTSVECPLEPNIDMQELLVDKCKVMNSKMRPLWLVFKNSDMQDGSIAVIYKNGDDLRQDM
LTLQTISIMDVLWKSEGLDLRMIPYGCLATGEGTGMIEVVTHANTIANIQKTRGGKMAAF
RHQTLIEWLEQNNTTKSEFDQAIENFTYSCAGYCVATFVLGVGDRHSDNIMVTEKGQLFH
IDFGHILGNFKTKFGIKRERVPFVLAHDFVHVINKGKNNNKADFDKFRKLCDNAFCILRR
KGYLFITLFALMVHSGLPELNSLDHLEYLRETLALHLTEQKALQQFRSKFNKALTDAWAT
SVNWFFHNVTRDNT
>F6X8V3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Equus caballus|TrEMBL
MCFNFMMPPAMADSLDIWSVDSQIVSDGSIRVDFLLPTGIYIQLDVPREAPISYIKQMLW
KQVCDYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRVKMRKFSEEKIQSLVGLSWMDWLQQTYPPEH
EPSNLENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIRGKEDE
VSPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVNCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYTNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>U6CV96|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neovison vison|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSVLENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDQPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A672QVM4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPAKTDQLDLWAESGLNGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGDAYEYSSHCTCDYVLDTASLKVSLHCTVTELMDQALKKWQTTHSPEEDIGTRS
DYVLRVSGRFEFLFEDHPLNQCKVRYVARNSLEMSNYIFQGTLLLIWQKYSTLHTVFRAM
GSLAAPIKIQVRAGLFHGTELLCKPAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCF
AIYAVMDKVKKQRSTKNTHLNKYQTIRSVLRKCLFFLCVADELEEMLNPIGTIQTNPYTE
NATELHISFPEYSTQPVVFPAFDKGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRY
DCRENFPQSLPKLLLSVKWSKHEDMALLQIWPKLSPRDALELLDFNYPDQYVREFAVICL
RDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWYLRSEMYMPAV
SVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVSELIKLGTIKTKTKQAHLKEAMMTC
LRQTGFIETLSDLQSPLNPNILLAGVHVERCKYMDSKMKPLWIVYNNKLLGGDTVSIIFK
NGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQK
TSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGNFRQY
CEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKF
DEALRESWTTKVNWMAHIVAHPS
>A0A672LGI3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDGTRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYSMPLEAGSLE
NLIDKHEGIIKITMHYDQSQVSSVNLDTASLKVSLHCTVTELMDQALKKWQTTHCPEEDI
GFRSDYVLRVSGKLEFLFEDHPLNQCKVRYVIQVRAGLFHGTELLCKTAVSSESSSRSEH
VWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVLEEML
NPIGTIQTNPYTENATELHISFPEYSTQPVVFPAFDKGRGGKKFYIELKEIMERDPLSQL
CENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMTQLQALLQIWPKLSPRDALELL
DFNYPDQYVREFAVYCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKI
GHFLFWHLRSEMFMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFGT
IKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGINVERCKYMNSKMKPLWI
VYNNKLLEGDTVDIIFKNGDDLRQDMLTLQILRLMDLLWKEAKLDLRIVPYGCLATGDHS
GLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGY
CVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVI
QQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKKHK
RYKLQSDLQISWIFYIHKHPLT
>A0A851YVG6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Halcyon senegalensis|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTADFYHSFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKTQGLSTKTSLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQNS
KLPGSFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGESEESAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A091X9J4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Opisthocomus hoazin|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDIILHSFFTKIAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTPSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGVSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSE
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESVKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>G3NS42|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gasterosteus aculeatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHDLFKEARKCPLHQ
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYSQLPTD
NFVMPSYSRRISTATSYMNGEAAVKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSSVKYPDMNAVEDHANWTISRELGFSYNLSGQSNRSARDHALTESDTEQMRQLSNRDPL
SEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLENPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKEVQMRFLVDQMKRPDYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A452FD07|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Capra hircus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRIPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKVSHLQAPGGGEGAWPLPPLVVQAGLFHGNETLCKTVSSSEVSVCSEPVWK
QRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQL
KTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAPHPVYYPSLDKIL
ELGRLGEHGRFTEEELQLREILERRGSGELYEHEKDLVWKMRHEIQEHFPEALARLLLVT
KWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLL
QLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSVALRFGLIMEAYCR
GSTHHMKVLMKQGEALSKLKALNDFVKVCSQKTPKPHAKEMMHLCMRQETYLEALSHLQS
PLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKNGDDLRQDMLTLQM
IQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKD
ALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFG
HFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCETAYTILRRHGLL
FLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNW
LAHNVSKDNRQ
>A0A7K4KMF6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crypturellus soui|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHVFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIVGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
LPGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSALDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITEA
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSVHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L0WJE2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alectura lathami|TrEMBL
MTPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKLQSGGESFTFQISPDEFPITLMSYAIKKQATVFRHETMENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANPPKTA
AKPPPLPKKKPNYSSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPTVAS
HPVYYPSFEQLLELGRNGEQPRIAAEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRHD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDLVKVSSQKATKPQTKEIMHM
CMKQETYLEALSHLQCPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGVGVIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
EKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A6I9JCC2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysochloris asiatica|TrEMBL
MDLENHEPPVVLRADNCRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNSKTPETVLLH
VASHGNVEQMKTQVWLRALEVSVAADFYHRLSPDHFLLLYQKKGQWYEIYDRYQVVQTLD
CVRYWKVLHRSPGQIHVVQRHAPSEETLAFQQQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVACRDPKLYAMHPWVTSKPLPEYLLKKISNNCIFIIIHRSTTSQTIKVSPDDT
PGTILQSFFAKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSSKPFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCGKAPALSGKASTETPSTESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISEKGEDQGSFNADKLTSATNPDKDNSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIISTDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSTLDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKHGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLNDFTQQVQVIEMLQKVTIDIKSLSVEKYDVSSQVILQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCSDPTALSKETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPLEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTCGKKTSAHFQKFQDVCARAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A672GY32|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salarias fasciatus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQLDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRIKMFRLSEERMQRVQMMTCTEWLQACFSPQLEPP
AATAVTDGVNDRAADLKVIIHFDQSQDLFSFSTMTWKWVTTHGPEEEAWGGQHVLRVSHC
LEFLCGDHPLIQYKYIRSCLQAKEPPHLTLVHTNTVKAMFDKEMTAIGAVVSRRSSNPPL
PLPPKRRTCVWDVSSPFKIVLVKGSKVNAEETAKVQVRAGLFHGTELLCKPAVSSESSGQ
RASSEHTWRDNTLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNSHINKYQTIRKAG
KVHYPIAWVNTMVFDFKGQLKTGDITLHCWSSFPDELEEMLNPIGTIQTNPYTENATALH
IHFPEYSSHPIIFPPFDKILEKAAEIVGASDCVSGARGGKKFYIELKEIMERDPLSQLCE
NEKDLIWTLRHDCWENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDF
NYPDQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGNRKIGH
FLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIK
NARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPNVQLSGINVERCRYMDSKMKPL
WIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGD
RAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFTLSCA
GYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIH
VIQQGKTGYTEKFGSFRQYCEEAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>B2RAH3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSAQTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKYFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>Q1WIQ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSAQTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGNYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A6B9QIS5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
TYVNVNIRGIDKIYVRT
>A0A6B9QKK2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
FLKVIEPVVNREEKILN
>A0A8D0YC75|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRFGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQASNEEGILSL
EKR
>A0A8D0JJG9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPGVDCPMEFWTKEENQSVDVDFLLPTGVYLNFPVSRNANLSTIKKHCLNSRPENPPRF
QFSAPPPPPVSVCVWGAPPRRQQLGWEAWLQYSFPLQLEPSARSWGPGTLRVPNRALLVN
VKFEGSEESFTFQVSTKDVPLALMPLVEQPEDYTLQVNGKHEYLYGSYPLCQFQYICSCL
HSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRTKPPPIPMKKPSSVSLWSLEQPFCIE
LIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSVCSDPVWKQRLEFDINVCDLPR
MARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVP
DEKGELLNPAGTVRSNPNTESAAALVIFLPEVAPHPVYYPSLDKILELGRHGEHGRFTEE
EQLQLREILERRGSGELYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNRHEDVAQMLY
LLCSWPELPGGGGPSCLLASGVSRRWVQPGREGLCGPPGEAQPPLPPSSSEMHVPSVALR
FGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQET
YLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNGDD
LRQDMLTLQMIQLMDVLWKQEGLDLREALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGY
CERAYAILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKF
NEALRESWKTKVNWLAHNVSKDNRQ
>A0A8J4L5Q7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eudyptes chrysocome|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCMSGNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQKRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGNRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEVVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6P8PHI7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCIPNGMIVTLECLREATLLGIKHNLFKEARKYPLFH
LLQDESSYIFVGVTQEAEREEFYDETRRLCDLRLFQPILKVIEPVGNREEKILNREIGFA
IGMPICEFEMVKDPEVQEFRRNILSVCKEALDLREASGPHSQALYVYPPNVESTPELPKH
IYNKLDKGLIIVTIWVIVFPNNDKQKYTLKIPHDCLPEQVIADAIRKKTRSMHLSPEQLK
LCVQEYQGKYILKVCGCDEYLLEKYPFSQYKYIRNCITIGRLPHLMLMSKESLYGQLPAN
IFIMPSYARRSVTSCYMNGDVPTKSLWSINSLLRIRILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYLTDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINLFDYKDTLVAGKMALNLWPVPHGLEDLLNPIGVGGSNPNKETPCLELEFSWYT
HAVKFPDTPQIEEHANWSMSRELGLNYCLVGLSNRLARDSSLIENEMEQLRNICNRDPLS
EITEQEKDFLWRHRHYCINIPETLPKLLLSVKWNSRDEVTQMYCLLREWPLIKPELSLEL
LDCNFPDPMVREFALKCLVKGLTDDKLSQYLIQLVQVLKYEQYLDNILARFLIKKALTNQ
RIGHFFFWHLKSEMHSKTVSQRFGLMLEAFCRGCGMYLKHLNRQVEAMEKLINLTDILKQ
EKKDETQKMQMKFLMEQMRRPAYMEALQGFICPLNPVHQLGNLRLEECRIMSSAKRPLWL
NWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIRIMENMWQNQGLDLRMLPYGCLSI
GDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWLKDKNKGEGYDAAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQVRKRKDAMLFHIDFGHFLDHKKKKFGYKRERVP
FVLTQDFLIVISKGIQECTKTKEFERDTIITSCIGLLSSALLRMKV
>A0A8C0R6E7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus dingo|TrEMBL
MEPQGREPRVVLREDHRRRRRRMKARGPAAGLPSMELIPIEFVLPTSQRSSKAPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYQRLGPDHFVLLYQKKGQWYEIYDRYQVVQTLD
CLRYWQLLHRSPGQIHVVQRRAPSAATLAFQRQLTALIGYDVTDLSNVHDNELEFTRRRL
VTPRMLEVAGRDPELYAMHPWVTSKPLPDYLRKRIPNNCVFIVIHRGTTSQTVKVSADDT
PGAILRSFFAKMAKKKALMGIPEGQSERDFVLRVCGRDEYLVGDTPLQNFQWVRQCLKNG
EEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRR
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFSIKI
KDLPRGALLNLQVYCSKAPTLSAKASADAPGAGSEARGKAQLLYYVNLLLIDHRFLLRRG
EYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDP
EGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKW
GQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLH
YLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLE
AYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLN
LPESFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDL
RQDMLILQILRIMESIWETESLDLYLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGN
TGAFKDEVLNHWLKEKCAIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETG
NLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQVIVTWGRP
TSCAIFRDYLNGRGGMLISVPGPQPKFNTQKPPALYTQQQAFLL
>A0A8D0ML99|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKSPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFH
IDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRH
HTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTV
QFNWFLHLVLGIKQGEKHSA
>A0A6P8Q0K4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCIPNGMIVTLECLREATLLGIKHNLFKEARKYPLFH
LLQDESSYIFVGVTQEAEREEFYDETRRLCDLRLFQPILKVIEPVGNREEKILNREIGFA
IGMPICEFEMVKDPEVQEFRRNILSVCKEALDLREASGPHSQALYVYPPNVESTPELPKH
IYNKLDKGLIIVTIWVIVFPNNDKQKYTLKIPHDCLPEQVIADAIRKKTRSMHLSPEQLK
LCVQEYQGKYILKVCGCDEYLLEKYPFSQYKYIRNCITIGRLPHLMLMSKESLYGQLPAN
IFIMPSYARRSVTSCYMNGDVPTKSLWSINSLLRIRILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYLTDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINLFDYKDTLVAGKMALNLWPVPHGLEDLLNPIGVGGSNPNKETPCLELEFSWYT
HAVKFPDTPQIEEHANWSMSRELGLNYCLVGLSNRLARDSSLIENEMEQLRNICNRDPLS
EITEQEKDFLWRHRHYCINIPETLPKLLLSVKWNSRDEVTQMYCLLREWPLIKPELSLEL
LDCNFPDPMVREFALKCLVKGLTDDKLSQYLIQLVQVLKYEQYLDNILARFLIKKALTNQ
RIGHFFFWHLKSEMHSKTVSQRFGLMLEAFCRGCGMYLKHLNRQVEAMEKLINLTDILKQ
EKKDETQKMQMKFLMEQMRRPAYMEALQGFICPLNPVHQLGNLRLEECRIMSSAKRPLWL
NWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIRIMENMWQNQGLDLRMLPYGCLSI
GDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWLKDKNKGEGYDAAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQVPRDVLQSLLGDSPASQPLHQPLLNDVGLRDAR
AAVL
>A0A093QWK8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phalacrocorax carbo|TrEMBL
MDLGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMVLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFSPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDTKI
KDLPKGALLNLQIYCGKAQGLSTKANLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTLQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTAGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A341BV46|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neophocaena asiaeorientalis asiaeorientalis|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
AKPPPIPLKKPASVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMQLCLR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A4Z2GNG4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Liparis tanakae|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDRQIIVVIWVIVSPSNDKQKYTLKIN
HDYVPEQVIAEAIRKKTRSMLLSQEQLKMCVQEYQGKYILKVCGCDEYLLEKYPLSQYKY
VRSCIMLGRMPNLMLMAKDSLYSQLPIDNFTMPSYARRISTATPYMNGETATKSLWTING
TLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMY
IPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTHTLVAGKMALNLWPVPHGL
EDLLNPIGVTGSNPNKSNRLARDNPLTDSDNEQLRQVCNRDPLSEITEQEKDFLWRHRQD
CVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAMELLDCNFPDPMIREFAVK
CLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSEMHN
KTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLKQEKKDEAQKVQMKFLVE
QMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWENPDMMSELLFQNN
EIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTI
MQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRSCAGYCVATFILGIGDRH
NSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREF
ERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALD
YFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A0F8CTB0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Larimichthys crocea|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTEELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYTLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRMLPYGCLSLGDCVGL
IEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRSCAGYCVA
TFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKG
SQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLA
LEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8B9WIE7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus grunniens|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFFPKSVDDQNLKVKFV
>A0A218UCA5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lonchura striata domestica|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K6KL54|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreocharis arfaki|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLPVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYSFPLQLEPVAKGLGT
GALQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDEDVFQYLLQLVQVLKYESYLDCELAKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6G1B4Y4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crocuta crocuta|TrEMBL
FLLLYQKKGQWYEIYDEHQVVQTLDCLRYWQALRRSPGQIHLVQRRAPSDETRAFQRQLT
ALIGYDVTDVSNVHDNELEFTRRRLVTPRTAEVAGRDPRLYAMHPWVTSKPLPEYLLKKI
TNNCIFIVIHRGTTSQTIKVSADDTPGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVC
GRDEYLVGDTPIKNFQWVRQCLKNGEEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGY
HEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLC
QRRTSPKPFTEEVLWNVWLEFSIKIKDLPRGALLNLQIYCSKAPVLPGKASAETPSSEAR
GKTQLLYYVNLLLIDHRFLLRHGEYVLHMWQISGKGEDQGSFSADKLTSATNPDKENSMS
ISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELL
WHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNF
SDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFL
FWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTDQVQVIEMLQKVTLDIKSLSAE
KYDVSSQVISQLKQKLENLQNSNLPKSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEF
KCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDK
IGMIEIVKEATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGY
CVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVM
GTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDAL
TVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A8C6EW75|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Marmota marmota marmota|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSCNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSLGA
GNASRVPSRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQLLVEQPEDY
TLQVNGRHEYLYGSYPLCQFQYICSCMHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKP
RTKPPPIPVKKPSSVSLWSLEQPFCIDLIQGSKVNADERMKLVVQAGLFHGNEMLCKTVS
SSEVSVCSEPVWRQRLEFDINVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIA
WANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGSVRSNPNTESAATLVICLPEVA
PHPVYYPALEKILELGRHGERGRATEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQ
ERFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKS
LRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPS
VALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCM
RQETYLEALSHLQSPLDPSTLLAEVCSVEQCTFMDSKMKPLWIMYSSEEAGSAGSVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRG
YCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>W5LYS0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lepisosteus oculatus|TrEMBL
ELKMPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLVTIKHELFKEARKYP
LHHLLQDETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREI
GFAIGMPVCEFDLVKDPEVQDFRRNILNVCKEAVDLRDANGPHSRALYVYPPNVESSPEL
PKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSPE
QLKMCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKESLYSQL
PIDNFTMPSYARRISTATPYMNGEASTKSLWSINSNLRIKILCATYVNVNIRDIDKIYVR
TGIYHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKE
VRPPGAQSRHSCSVLGEEHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIG
VTGSNPNKETPCLELEFDFFSSPVKFPDMATVEDHANWTVSRESNRLARDNALTESDTEQ
LRLVCNRDPLSEITEQEKDFLWRHRHYCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDW
PAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLV
RFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAME
KLINLTDILKQEKFGKNESDKESEELLLVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQL
GNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIME
NIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWL
KDKNKGEMYDLAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHK
KKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINL
FSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHT
IRQHALN
>A0A7L0DS25|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Trogon melanurus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PEMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
TQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEVVAKTYQLLAKKDVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHNFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K7P0I3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acrocephalus arundinaceus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIILLE
IAGNCTVEQMKAQIWMRAIEMSQTSDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIITTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A674AF07|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MEQQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKHLPEYLLSKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPEDVCEGDYILRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFN
IRIRDLPKGARLSLQVSCGKAQTQISKGTSSYQDNGGSPVGGGSSSHDGNKTKSRLLYYV
NLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYC
YPVALPKSREGKEAGGEGREAEGGERGQREMPNHLRKQFESIVETDPLHPLSQEDKELLW
HFREECMRHPRAYPKLLGSVRWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYS
DAHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLF
WFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEK
YDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFK
RADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKI
GMIEIVRDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYC
VATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMG
TSGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALT
VGRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGGDKRSA
>A0A674D519|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MEQQVSDEEPQPVVLREEIRRRRRKMKAFTSTFSVAMDQIAIEFILPTTTKSSRSPDTLL
LEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSSDHCILLYQKKGNWCEIYDKHQVFQT
LDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRKNELSDRDPKLYSMDPWITSKHLPEYLFTKVTNSHILLVIHRNKASQTIKVSID
DTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCLK
NGEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDCH
RKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFNI
RIRDLPKGARLSLQVSCGKAQTQISKGTSSSYQDNGGSPGGGGSGSHDGSKTKSRLLYYV
NLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAIAILLDKYC
YPVALPKSREGKVAGGEGREAEGGERGQREMPNHLRKQFEAIVETDPLHPLSQEDKELLW
HFREECMRHPRAYPKLLGSVLWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYS
DAHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLF
WFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEITEALQKVTREIKAMSAEK
YDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFK
RADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKI
GMIEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYC
VATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMG
TSGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALT
VGRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGGDKRSA
>A0A7K9BYU3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Psilopogon haemacephalus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLPVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNIKFESGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWRQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALLICFPSVAP
HPVYYPSFEQLLELGRNGEQLRAAPEDPEEKQQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEAVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGY
CEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKF
NEALRESWKTKVNWLAHNVSKDNRQ
>A0A8B9IDU6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anser cygnoid|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7L3EIU0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chaetops frenatus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQRPEDYT
LQVNGKSEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSAPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSS
SEVSVCSEPVWKQRLDFDINICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKMGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDLYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L3E8N0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chaetops frenatus|TrEMBL
MELGDHAQPVVMREENKRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLEI
AGNCTVEQMKAQIWMRAIEMSQTTDFYHSFTPDQFILQYQKKGQWYEIYDKHQVLQTLDC
ILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRLV
TPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDTP
DMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNGE
EIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRKF
RVKIIGIDIPILPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKIK
DLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRSG
EYVLHMWKIPGKGVEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSDP
QGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKRPKAYPKLLSSVKW
GQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDHVLH
YLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILE
AYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGSK
LPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDL
RQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKYATTIAKIQQSTVGN
TGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETG
NLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAYL
ALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDK
GWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K6X3Y8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Promerops cafer|TrEMBL
MELGDQEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVFRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTSLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRLSSD
PQGDRTRAEMPNQLRKQLEEIVATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVSKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K6XUA2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Promerops cafer|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDAVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGT
GSLQIPTKNIFVNVRFQSGGESFTFQISPWEFPVTLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
CKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSS
SEVSVCSEPVWKQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRFVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P6GYF3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Puma concolor|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGAPRESFTFQVSSKDVPLALMACALRKKATVFRQPLLERPEDYTLQVNGKHEYLYGS
YPLCQFQSNPAPQVQKPRTKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLV
VQAGLFHGNETLCKTVSSSEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAK
KARSTKKKSKKADCPIAWANLMLFDYKDQLKTGECCLYMWPSAPDEKGELLNPAGTVRSN
PNTESAAALVICLPEVSPYPVYYPALDKVSPLANLAWRDPPSPEAVGLKMTFPDPASGDP
QNLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGLGVKAYTILRRHGPLFLHLFALMRAAGLPELSCSKD
IQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q1FFU5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acanthochromis polyacanthus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRISEERMQRVQMMTCTEWLQARFSPQLEPA
AGTAITDGVSDRPSDLKVIIHFDQSQDSASLKVPSSSTPTELIEMALKKWLTTHRPEEEA
WKGQYMLRVSHCLDFLCGDHPLIQYKYIRTCLQAKEPPHLTLVHTSAVKAIFDKEISAIG
AVVSRKSSNPPLPLPPKRRVPTQVQTCVWDVSSPFKIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPVVSSESSLRSDHTWKDSTLEFDISVCDLPRMTRLCIAIYAVMDKVKKQKST
KNAHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATELHIHFPECSSHSIIFPPFDKILEKAAEIAKANECAPIGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRHDCHENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLSPRDALELLDFNYPDQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAQGNRRIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALS
KLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGI
NVEKCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAN
LDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSG
DALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A2I0U7U7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Limosa lapponica baueri|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTVDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C5IYN6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Junco hyemalis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMAVIEEHANWTISRELGFNYSYAGQSNRLARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C8BSJ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Otus sunia|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQSINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFHIVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSIQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7J7X6P5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinolophus ferrumequinum|TrEMBL
MPPGVDCPMEFWTKEENQTVAVDFLLPTGVYLNFSVSRNANLSTIKKVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLSWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSMSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALIICLPEVAP
YPVYYPALDKILELGRHGEHCRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQLPQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAI
KSLRKLTDDEVFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PSVALRFGLIMEAYCRGSIHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPHTKELMHL
CMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYNNEEAGSDGSVGII
FKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANI
QLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFR
GYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRV
KFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C7WNP5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias sinensis|TrEMBL
MDQTMVSDEEPEVPREECRRRRRKKAITSSSCVSMDQITIEFVMPSAARGGSGPDILTLD
VAGNWTVEQVKAQVWMKAVTLNLCPDFYQRLSPDHCILLYQKKGTVCEIYDKHQVFQTLD
CIPYWRALKKGVGRIQMVTRPQLSEESLQYQRYLNGLIGYDVTDVSNVHDDELEFTRRKL
LTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLAKVNNGHILVVIHIGTVSQTIKVSINDT
PSQVLASFFAKTSNKRVLLGIPDDVCEADFVLRVCGREEFLYGEKPLQNFNWIRQCLKNG
EEIHLLLEKPPDPELDVVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRK
FRVKVLGIDIPTLPKVPELVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKI
KDLPKGARLNLQVICGKPTQTPASKGSSHHDNSNRLLFYVNLLLVDHRSLLRQGEFILHM
WKMPEKSDESSSSINADKLTSATNPDKSSSMAVAILLDKYCYPVVLPKSRDVGRDSGAGE
EMEGGERGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRQECMRDPRAYPKLLGS
VKWGKQEDVLATHRLLERSNAWDTSGLDVGLAMQLLDCHYSDSHVRSMAVRKLETLEDDD
VLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAV
LLEAYLRGCGESMLQDFRKQVEMTMALQKVTREIKAIAADKYDVSAQVVFQLRQKLETLQ
SSGLPETFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDG
DDLRQDMLILQILLIMESIWETECLDLCLLPYGCISTGNKIGMIEIVKDATTIANIQQRV
VGSTGAFKDEILHQWLRDKCVSEDKFQQAVERFLLSCGGYCVATYVLGIGDRHNDNIMIT
ESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFLKFQDVCVK
AYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEEEAQRHLLDQIEIC
REKGWMVQVNWFVHLVLGIKQGVEKRST
>A0A3B4XTI9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola lalandi dorsalis|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKALWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A7L0AQW8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ciconia maguari|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSDKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKVKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGVSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A665UA90|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MSPGKYGMQEDWEKDGVQEIMMDFLLPTGILLNFPVSRNDTIKNIKRMVWKNARSEALFN
ALGDSDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNHEVNEFRSKMRTFCEEKAQERQQLSWQQWMEYSFPCDLEPCCFPCGS
AKSKNTKKIFINIKFEACDSFMLQQDPQDLPEALIRNALKKKATVFRSVRQEPGDYTLRC
NGTWEFIYGNHPLCQFKVSSHKTPSLVKCPTFTDQYDQQHMYNKNPPQPTNAPLSFSCFL
IAKQLNLVKLVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQRLEFDINVADLPRMSRLC
FALYAVIEKTKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSD
LLNPMGTVEKNPNVDSAAGLLIHFPNIRQYPLYYPPLDKICDLEKNEIMDNKNYTEFFED
EKELLWKLRADVREYYPESLSKLLLITKWNKREDVVQMVSLLRNWPDLPVIQALELLDYS
FPDPAVRSFTVRCLRKLSDDEILQYLIQLVQVLKYESYLDCDLTTFLLERQKAQNHVHLL
SCLLQGEHPPHQALTSALQNEALGKMKALSDFVKSGSQKMTAEDLKLCIRQESYLEALSD
LLSPLNPSIILEEICADKCRFMDSKMRPIWLMYKNQWAQGDMMGIIFKNGDDLRQDMLTL
QMIQLMETLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNNSNSAATAAFN
KDALLNWLKSKNPEEKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHID
FGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTSNSEKFERFREYCERAYKILCRNG
TLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKV
NWMMHSLAKDNRP
>A0A8J6K8E3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eleutherodactylus coqui|TrEMBL
MPPGVYCPVDFWAKEEKQSISVDFLLPSGIYLNFSVPCSASLGNIKKILWQRAQQEPLFH
TLGSPTSYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAEKLLNSQISLL
IGKGLHEFDSLNDPEVNDFRSKMRQHCEESALQRQHMNWDSWMESNFPLRLEHFSKAFTK
TSQSNKTLMINVKFEGSEESFTLQVSPRDFPLSLIRMALRKKSNVSGQQCPGRPDDYILQ
VNGVLEYIYGNYPLCQFTHINHCLRFSCTAHLTLVTIASTLPDQQGDAIVSSKIRHKPPP
LPTKKPHHCSLWKLERPFCFQLLYGYNVNADDGLKLLVHCGLYHGSELLCKTVASSEVNA
SSDPQWFQLLDFDINTCDLPRMTRLSLALYAVDKSKKAKSTKKKSKKTDYPIAWVNTMLF
DYKDMLKCGEYSLCMWSSFPDEKGEMLNPMGTVHCNPNTESAATLSICFVNVSDYPVYYP
SIEKILELGRLGEVSNATPDERQQLLEIVERKGQAELYEHEKELVWKLRHEIKERHPEAL
PKLLLTTKWNKHEDVAQMVYLLQTWPELPVLTALELLDFNFPDRHVGSFTMSCLKKLTNE
ELCQYLLQLVQVLKYESYLDCELTMFLLDRALIHRKIGHFLFWHLRSEMHVPAVALRFGL
ILEAYCRGSIYHMKVLMKQGEALSKLKGLNDFVRSSVQKTSKAQAKEAMHMCMRQDTYLE
PLSHIYSPLDPNLILTDVCVELCTFMESKMKPLWIVYNNDMLGGSRVGIIFKNGDDLRQD
MLTLQMIKLMDVLWKKEGLDLRVTPYGCLSTGDKTGLIEVVMHSDTIANIQRNKSNMAAT
AAFNKDALLNWLKSKNPGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQL
FHIDFGHFLGNFKTKFGFNRERVPFILTYDFVHVIQQGKTNNSEKFER
>A0A8D0G8Y5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphenodon punctatus|TrEMBL
MPPAMTDAFDIWAVDSQIGSDGSISVDFLLPTGIYVNLDVPREATISHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKVVTRSCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVKEFRRKMRQISEEKIQSLVGLSWMDWLKHTYPPEQEPSLPE
NFQDKLYGGNLVVAIHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGRNDEEVEPYD
YVLQVSGKLEYVFGDHPLIHFQYIHHCVMNRTLPQLTLVESSSIKKMCEREMISIEAAIN
RKSSNLPLPLPPKKSRIISVWEVTTPFKIELVKGNKLNTEETAKVHVKAGLFHGTELLCK
PIARSELSGKNDHAWNETLEFDINICDLPRMARLCFAVYAVMDKMKTKKSTKTINPSKYQ
TIRKAGKVHYPVAWVNTMVFDFKGQLKTGDLILHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIRFQEYSKLPIYYPPFDKILEKAAEIARNSDSVGMAVSIRLKEIMERDPLSQLC
ENEMDLIWTLRYDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPREALELLD
FNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIG
QMLFWHLRSEVHIPAVSVQFGVILEAYCRGSVAHMKVLSKQVEALNKMKTLNSLIKLNAM
KQSRAKGKDTMHTCLRQNAYREALSDLQSPLNPSVLLSELHVEKCKYMDSKMKPLWIVYN
NKVFGGDLVGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLNLRVLPYGCLATGDHSGLI
EVVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEAFTLSCAGYCVA
TYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQG
KTGNTEKFGRFRQCCEEAYLILRRHGNLFITLFALMLTAGLPELSSVKDIQYLKDSLALG
KSEDEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C5BLD0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MPPGNYGMEEEWEAEGNADIMVDFLLPTGIFLEFPVSRNDTIADIKKLVWRRASSEPLFN
ALGDPASYVFVCISSAAERLELEAEHRRLADVRPFACFLQLVAREGDRAEKLANAQISLL
IGKGINEFEAQKNHEVSEFRARLRAFCEEKALQQQALPWFQWMECNFPCDLEPCRALPSR
GGGAKAPKKIFINIQFEGSDESFMLQQDPQEPPLALIRSALKKKATVFRWVRQEAEDYTL
RVNGRWDFLYGDHPMCQFKVTPDLYPPPTPPLRHLWGLCLSLEPLCIHLLQGSRVNADEG
MKLVVQAGLFHGSELLCKLVTSSEVAVGSDPVWNQRLEFDINVADLPRMSRLCIALYAVV
EKAKKPRGTKKKSKRADCPIAWVNTMVFDYKDQLKTGEFLLSMWPSIPDDKSELLNPMGT
VEKNTNVDSAAALLIHFPSVRPQPLYYPPHDKVTGGGGSRAPHRSSHVRLKEIMDNKNHT
EFFEDEKELLWKLRGAVQSLYPESLSKLLVITKWNKREDVAQMVGLLRAWPELSGLHALE
LLDYSFPDPSVRAFTVKCLKKLGDRELMQYLIQLVQVLKYESYLDCDLTSFLLERALSNK
RIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGNIHHIRSLTKQNEALGKLKALSDIVKS
GSQKMSADDLKLCIKQDSYMEALSDLLSPLNPSIILSEICVEKCKYMDSKMKPLWLMYKN
QWVPGDLMGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIE
VVKNSDTIANIQRDNSNSAATAAFNKDALLNWLKSKNPEHKLEQAIEEFTLSCAGYCVAT
YVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGR
TNNSEKFERFRDYCERAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGK
TEEEALKSFKVKFNEALRESWKTKVNWMMHSLAKDKRP
>A0A8C3R8L2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyanoderma ruficeps|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWQQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMNYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCLTSPPKAV
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVAVCSEPVWRQRLDFDIGICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C1EHR7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
LVLSAMPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKE
AQTYPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFRAYHSCLSSKLITRNCG
RAERILDSKIGVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCY
STQLETESVENLIDKHEGVIKITMHYDQSQVCSVILALKKWQTTHGPEEDIGTRSDYVLR
VSCRLEFLLEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAIFEKEICTIGSVLARKAS
NPPLPLPPKKRTPTVRTLSVFPALQLIKGALSFVPLAAPNSNAKVIIFLNRFIKHNTPFI
LHLVILKKQRSTKNTHLNKYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSF
PDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVFPAFDKGRWGDPLSQLCENEK
DLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYP
DQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLF
WHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKLGTIKTKT
KQAHLKEAMMTCLRQTGFIETLSNLHSPLNPNILLAGVHVERCKYMDSKMKPLWIVYHNK
LLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLR
>A0A8C2EP05|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLETESVE
NLIDKHEGVIKITMHYDQSQVCSVILALKKWQTTHGPEEDIGTRSDYVLRVSCRLEFLLE
DHPLNQCKYIRDCLLANESPHLTLVHCDVVKAIFEKEICTIGSVLARKASNPPLPLPPKK
RTPTVRTLSVFPALQLIKGALSFVPLAVRAGLFHGTELLCKTAVSSESSSRSEHVWNKTL
EFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHYPIAWVNTMV
FDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVF
PAFDKILEKAAEIAGASDSMTIGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRYDC
RENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVN
CLRDMRNAEIDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSE
MYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKLGTIKTKTKQAHLK
EAMMTCLRQTGFIETLSNLHSPLNPNILLAGVHVERCKYMDSKMKPLWIVYHNKLLGGDT
VGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADT
IANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGD
RHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKF
GNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALK
QFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A8C2GZ77|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSPELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKVFRQFRYADYVALRISVCLFLDNFTMPSY
ARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGIYHGGEQL
CDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNV
NLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSSPVKFP
DMATIEDHANWIISREMGYNYCQSGQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEV
AQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLK
YEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLK
HLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQ
LGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIM
ENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQW
LKDKNRGEMYDMAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDH
KKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFI
NLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIF
HTIRHHAQN
>A0A7L1L6J4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Himantopus himantopus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQNPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRVAPEDPEEKLQLKEILERRTHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8J4WTN8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Clarias magur|TrEMBL
MLVSLECLREAPLTSIKQQLFTEARKYPLYHLLQEESCYIFVGVTQEAEREEFYDETRRL
CDLRLFHPILKVIEPLGNREEKILNREIGFAIGMPICEFELVKDSEVQDFRRSILSVCRE
AMDEREGGGPHARALYVYPPSVESSPQLPQHIYAKLDKGRLIVTIWVVVSPSNAKQKYTL
KIAHDCVPEQLIAEAIRKKSRSMHLSAQQLRLCVQEYQGQYILKVCGCDEYLLEKYPLSQ
YKYIRSCITVGKLPHLMLVSKDSVYDQLPCSGFVTPSYSRRTPQPSPSPGGGDPANPLSL
WTVNPHTPLRIRLICATYVNVNMRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNE
WLMYDIALIDLPRAARLCLSICSVKGRKGAKEEHCLLAWGNVNLFDYKDTMVSGKVALSL
WPVPHGLEDLINPIGVAGSNPNKETPCVELEFPSFNHTVVFPDEQQIEEHANWIISRELG
YNYSLSLSNRLVCDSSISQAETEQLRALCNRDPLYEISEQDKDFLWRHRHCCVNTPESLP
KLLLSVKWNSRDEVSQMYCLLRDWPLMQPETALELLDCNFPDPMVREFALRCLMQGLSDD
KISQYLLQLVQVLKYEMYLDNPLARFLVKKALTNQRIGHFFFWHLKSEMHNKTVSRRFGL
LLEAFCRSCGIYLKHLNRQVEAMDKLVNITDTLKHEKKDETQKTQMKFLVEHMSRPDYME
ALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFTNNEIIFKNGDD
LRQDMLSLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSFTIMQIQCKGGL
KGALQFNSNTLHHWIRDKNKGETYDSAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKEN
GQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQECTKTKEFE
>A0A8C2G9U7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWVESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQNIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKRISEEKMQCMQLMSWGEWLRSCYSMTLEAGSLE
NLIDKHEGVIKITMHYDQSQDTSSLKVSLHCTVTELMDLALKKWQTTHVPEEDIGFRSDY
VLRVSRKLEFLFEDHHLNQCKYIRDCLLTNESPHLTLVHCDVVKAMFEKEISTIGSVLAW
KTSNPPLPLPPKKRLPTLHTCVWKVHSLFRIHLVKGNKVNAEDAAKIQVRAGLFHGTELL
CKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNK
YQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPY
TENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMER
DPLSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPR
DALELLDFNYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERA
QSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNE
LIKFGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGVNVERCKYMDSK
MKPLWIVYNNKLLGGDTVDIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRDALDKAI
EEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPF
ILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSV
KDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A7K8ZWT8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Grallaria varia|TrEMBL
MPPGIYCPTEFWSKGENQSIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLGWAAWMEYNFPLQLEPMAKGFGT
ASLQTPTKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPRMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGDQPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMIFLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L2DFW2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Catharus fuscescens|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVRDPEVSDFRAKMCQFCEEKAAKRQQLGWAAWMEYNFPLQLEPVAKGLGT
GSQQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIRKQATVFRHETVQRPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCVQRGLTPHLTMVHSSAILAMRDEQNSCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVSDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3P8TUH0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amphiprion percula|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESCPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYQDILVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAADAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A8C2VUW5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chinchilla lanigera|TrEMBL
MAPGVDCPMECWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRVVAREGDRVKKLINSQISLL
IGKGLHDFDSLRDPEVNDFRAKMRQFCEEAAVRRQQLGWEAWLQYSFPLQLEPSARSGGP
GAPLIPNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGRHEYLYGSYPLCQFQYICSCLHNGLTPHLTMVHSSSILAMRDEQGDPAPQVQKPR
PKPPPIPSKKPSSMSLWALEQPFCIELIQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANIMLFDYRDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVICLPEVAA
HPVYYPALDKILELGRHGEQRGHITEEELQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWHKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSTGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGSGAASFMLEEEAAAQRRGFQSPQRRRDALDRAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFIL
TYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKD
IQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A094LY57|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podiceps cristatus|TrEMBL
SRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYSFPLQLEPMAKSL
GTGPLHTSTKNIFVNVKFKSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPK
MAAKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQDLSGLSKSSRLRLSPAYALSCDSHEQKLQLKEILERRSHTELYEHEKD
LVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPD
RYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFW
HLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKP
QTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETG
GGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMH
SDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGTSENKSELHRSCKQHSKLRGIGDRH
SDNIMIRETGQVW
>S7P5W7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myotis brandtii|TrEMBL
MKPRGSAASLSSMELIPIEFVLPTSQRTSKTPETALLHVAGHGNVEQMKAQVWLRALETS
SAADFYQRLSPDHFLLLYQKKGQWYEIYDKYQVVQTLDCLRYWKVLHRSPGQIHVVQRRG
PSEETLAFQRQLTALMGYDLEFTRRRLVTPRMAEVAGRDPQLYAMHPWVTSKPLPEYLLK
KIAHNCIFIVIHRSTTSQTIKVSADDTPAAILQSFFTKMAKKKSLMDIPESQSEQDFVLR
VCGRDEYLVGETPLKNFQWVRHCLKNGEEIHLVLDAPPDPAQDEVRKEEWPLVDDCTGVT
GYHEQLTIHGKDHDSVFTVSLWDCDRKFRVKIRGIDIPVLPRNADLTVFVEANIQHGQQV
LCQRRTSPKPFTEEVLWNVWLEFSIRIKDLPKGALLNLQIYCGKAPALSGKASAETTSPE
ARGKAQLLYYVNLLLIDHRFLLRHGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKDSS
MSICILLDNYCHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKE
LLWHFRYESLKHPKAYPKLFSSVKWGQQEMVAKTYQLLARREVWDQSALDVGLTMQLLDC
NFSDENVRAIAVQKLESLEDDDVLNYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGH
FLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLRDFTQQVQVIEMLQKVTIDIKSLS
AEKYDVSSQVISQLKQKLENLQNSNLPKSFRVPYDPGLKAGALVVEKCKVMASKKKPLWL
EFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWEIESLDLCLLPYGCISTG
DKIGMIQIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKAAVERFVYSCAGY
CVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVM
GTSGKKTSLHFQKFQEVCTKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDAL
TVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A670J8E4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podarcis muralis|TrEMBL
MPPGIACPVEFWSKEANQSIQVDFLLPTGIYLTLSISCNASLNTIKQMVWHHAQFEPLFH
MLSGPESYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDALSDPEVNDFRTKMHQFCEERVTRRQQLSWKAWMEYSFPVQLEPSSSSLGR
KSPLQVPNKNIFVNVKFESGGESFTFQISPKEFPVTLMSYAVKKQATIFRHQRMNSPEEY
ALQVNGKCEYLYGNYPLYQFQYIRDCLHRGLLPHLTMVHSTSIMALWEEQTNGITHPSKA
SPKPPPVPKKKPNSISLWSLEQPYYIDLVQGSKVNADERMKLVVQAGLYHGHEMLCKMVS
SSEVNVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIA
WVNIMLFDYQDQLKTGECCLPMWSSFPDEKGELLNPTGTVRTNPNTESAAALVIRFPGIL
LYPVYYPSFEQIMEHGRNGQCPRYMSEDPEEQQLKEILERRSHTELYEHEKDLVWKMRHQ
VRDQYPGALAKLLVVTKWNKHEDVAQMIHLLQSWPELPVLNALELLDFNFPDRYVGSFTV
NSLKKLTDAELFQYLLQLVQVLKYESYLDCKLTTFLLDRALSNRKIGHFLFWHLRSEMHV
PSVALRFGLILEAYCRGSTHHMKSLMRQSEALNKMKALNGIVKLSALKNPKPQTKEFMHT
CLRQETYLEALSNLQSPLNPSVILAKVSVELCTFMDSKMKPLWIVFNNEEIGGTSNVGII
FKNGDDLRQDMLTLQMIQLMDILWKKEGLDLSDALDRAIEEFTLSCAGYCVATYVLGIGD
RHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKF
ERFREYCERAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEARK
HFQLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A384A0T2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balaenoptera acutorostrata scammoni|TrEMBL
MELESHEQHVVLREDNRRRRWRMKPRSAAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLSPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRLAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNYIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFRXXX
XXXXXXXLNLQIYCGKAPALSSKASAEAPAPESRGKAQLLYYVNLLLIDHRFLLRHGEYV
LHMWQLSGKAEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEGD
RVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQQ
EIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLL
QLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYL
RGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLEILQNLNLPQ
SFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSKETIGIIFKHGDDLRQD
MLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGA
FKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLF
HIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALR
HHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEEAKKYFLDQIEVCRDKGWT
VQFNWFLHLVLGIKQGEKHSA
>A0A2K6T7L4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Saimiri boliviensis boliviensis|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLNGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRTKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKSTVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPAKKPSSVSLWSLDQPFCIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDISISDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLHMWPSVPDEKGELLNP
TGTVRSNPNTDSAAALLICLPEVAPYPVYYPSLEKGGMLLASDGWRPELLWLSLHARDST
PSRMIGVETPCLGIPPGLDAEGSCLLQILELGRHSECVRVTEEEQLQLREILERRGCGEL
YEHEKDLLWKLRHEVQERFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLGALELL
DFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKI
GHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSS
QKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMY
SNEEAGSSGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTG
LIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYC
VATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQ
QGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLA
LGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A087RKQ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aptenodytes forsteri|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQKRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGNRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEVVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDICVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A087QL61|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aptenodytes forsteri|TrEMBL
SRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGL
GTGPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPK
MAAKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQGLSGLSKSPGLRLSPVYALSCDSHEQKLQLKEILERRSHTELYEHEKD
LVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPD
RYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFW
HLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKP
QTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEERG
GGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMH
SDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLG
IGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNN
EKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEE
ALKHFRLKFNEALRESWKTKVNWLAHNVSKDNR
>A0A668UIX7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRSKMFRISEERMQQIQMMTFSEWVQACYSPQLEPA
AVTAITAGVNDAPVDLKVIIHFDQSQDSASLKVSLSCTPNELMEQALRKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKETPHLTLVHTSAVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRRAPTQVQTCVWDVPKPFRIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSNESSGRSEHTWKDNTLEFEISVCDLPRMTRLCFAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHPIVFPPFDKILEKAAEMVSADCVSIGRGVKKFYMEL
KEIMERDPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTH
FLLERAQRNRQIGHFLFWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRIVPYGCLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8D0DEF2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MPPAMTDLLDIWAAHSPLAGHALDQITVDFLLPTGIYIQMVVPREATIQHIKLLLWKQAQ
SHPLFSSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRSCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRLSEERMQQVQMMTCTEWLQACFSPQLEPL
AGTAITDGLNDRPADLKVIIHFDQSQVPSSCIPSDLMELAVKKWLTTHAPEEEVWLGQYI
LRVSHCLEFLCGEQPLIQYKYIRTCMQAKESPHLTLVHTSTVKGMFDKEISAIRAVVSRK
SSNPPLPLPPKRRVPTVSSVINSHWQAGLFHGTELLCKPAVSSESSGRSDHTWKDSTLEF
DLSVCDLPRMTRLCFAIYAVMDKVKKQKSTKNAHINKYQTIRKAGKVHYPIAWVNTMVFD
YKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATALHIHFPEYSSHSIVFPP
FDKILEKAAEIAGASDCVPMGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCRE
NFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCL
RDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGNRKIGHFLFWHLRSEIHMPAV
SVQFALMLEAYCRGNIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSKTKEAMLTKEA
MMTCLRQSGYSETLSDLHSPLNPNVLLSGINVERCRYMDSKMKPLWIVYNNKLLGGDTLG
IIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIA
NIQLTSSNVAAAAAFNKDALLNWLKERNTGDALDRAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGS
FRQYCEEAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEDALKQF
RQKFDEALRESWTTKVNWMAHNVAKDNRS
>L9JDD4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tupaia chinensis|TrEMBL
MPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQMEVPREATISYIKQMLWKQVHNY
PMFNLLMEVDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRRKMRKFSEEKIQSLVGLSWMDWLKQTYPPEHEPSVLE
NLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMSPIKVNELAIQKRLTIHGKEDEASPCDY
VLQVSGRVEYVFGDHPLIQFQYVRNCVMSRTLPHFILVECCKIKKMYEQEMLAIEGAIQR
SSSTPPLPLPPKKTRIISHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TIVSSEISGKNDHVWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQ
TIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIKFPENKKQPYYYPPFDKSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQ
DCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYA
VECLQQMRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAM
KLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYN
NKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLI
EVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVA
SYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQG
KTGNTEKFGRFRQCCEDAYLVLRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALG
KSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>L8YEE1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tupaia chinensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKISHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETATKSLWVINSALRIKILCATYVNVNIRDIDKMYCLVKD
WPPIRPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLL
VRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAM
EKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEEC
RIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQSQGL
DLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEI
YDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQVMPSLCASLSLPAAVLTGRFQ
EMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMK
QMNDAHHGGWTTKMDWIFHTIKQHALN
>V9K9P2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MENKTNIEKNDELPIVMREENKRRRRNMRANTTRGMQYYSLEQLSIEIILPTRNKRTAMH
EKISLDIAGNYTVEQLKTKIWVKANGTSGSPEYYQKFSPDQFILLYQKKGQWYEIYDKQQ
VIQTLDCINYWKVLQKSVGKIHVVQKARSSDQSLQLQWDLNNLVGYDVTDVSNVHDDELE
FTRRTLITPRLTEVATRDVRLYSMDPWILSKPLPEYLLNKISGNNIFMIIHRGAVSLTIK
VSIDETPESILRNFFKKMAKKMSLLDMNESHSEEHFVLRVCGRDEYIVGDNPIKDFFWIR
NCLKNGEEIHLVLDLPPDPVLDEVQKEEWPLVDDCTGVTGSHEQLTLEGKDHEKVFTISL
WDCSQTFRVKIVGIDIPVLPRNTDVTVFVQASILHGQQILAQQRTPAKAFTEEVMWNMWL
EFDIKVKDLPKGARLNLQVYCGKAQALGSKALEDLWDSRSKNNMLYYVNLLVIDHRSLLR
QGEYLLHMWKIPNKGEEQGTIEADKLTSATNPDKQTSMAICILLDRYNYPIALPRSRQTD
PEAERSGPEMHSQLRKQFEEIVSTDPLNPLSAEDKELLWHFRHECVKQPKAYPKFLSSVK
WGQQDVVLKTHQLLQKQTAWASSPLDVGLALQLLDCRFSDEQVRTMAVQKLETFGNDDVL
RFLLQLVQAVKFEPYHDSALARFLLKRALGSKRIGHFLFWFLRSEVSESMHYRQRYAVML
ECYLRGCGQAMLMDFMKQVKVIKELQKLTKEIKNVTADKYDISSQAISQLRHRLEKLQSS
GFPECFRVPYDPGLRAGALVVDKCKVMASKKKPLWLEFKCADPTSVSKDTIGIIFKQGDD
LRQDMLIIQILLIMDSIWEMESLDLCLLPYGCIATGNKIGIIQIVKDATTIAKIQQSTVG
NTGAFKDEVLNHWLKEKCVIEEKFQSAVEKFVFSCAGYCVATYVLGIGDRHNDNIMITES
GNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLFVMGTYGKKTSPHFQKFQEICLKAY
RTLRHHANLLIILFSMMLMTGMPQLTSKEDIEYIRETLTVGKNEEEARTHFLEQIEICPD
>A0A4W3H592|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPGMQYHQDLWSEDENPDVEVEFLLPTGIYLNFYVPRSSTISYIKKLLWQQAQQQPLFH
TLNEPDAYVFTCINHTAEREELEDERRRLCDVRPFLPVLKLVAREGDRAEKLINSQISLL
IGKGLHEFDCMQDYEVAEFRLKMRQFCEDKESERLRMSWQDWMEYSFPRELDCLCSVPRP
NLNLYLLNQESFSFQISPQSHPGTLMQMAVKKKATVFRHKTVEHTEDYTLQVNGTEEYIY
GNYPLGQFKVSSLWYNINNDNSLVQELRSLVAEGIRASFHRCFPFSPPQLVVQAGLFHGS
EMLCKTVSSHEVSVCSEPAWDQALEFDIHFSDLPRMTRLCFALYGVIDKAKKARSTKKKS
KKADCPIAWVNTMVFDYKDQLKTGDVWLHMWPSIPDEKGELLNPMGTVQGNPNTDSAAAL
YVRFRNMGSYPIYYPSFDKVCTELIPRGLLCLDGLKEIMERKSCTEFFEDEKDLVWKLRW
ESRDHYSDALAKLLSITKWNKHEDVAQMIYLLQSWPELPALHALELLDYSYPERYVRSFA
INCLKNLSEEELFQYLLQLVQVLKYEPYLDSELTKFLLNRALANKKIGHFLFWHLRSEMH
VPAVSLRFGLILEAYCRGNNYHMKSLMKQCESLKKMKALNDFVKSSSQKTTKPKTKEALH
LFMRQEAYMEALSNLHSSLNPSSLLTDLWVDKCKFMDSKMKPLWIVYKNEKYDGDPMGVM
FKNGDDLRQDMLTIQMIQLMDVLWKRQGLDYRMIPYACLSTGDKTGLIEVVSRSETIANI
QLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRENGQLFHIDFGHFLGNFKSKFGINRERVPFILTHDFVHVIQQGKTSNSEKFERFR
KYCEHAYMILRKHCPLFINLFALMRAAGLPELSSSKDIQYLKDSLALGKTEEEALKHFKM
KFDEALRESWKTKVNWMAHNVAKDNRS
>A0A3B4CUQ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pygocentrus nattereri|TrEMBL
MPPGVYYGMQDVWEKEGREQVNMEFLLPTGIYLSFPVARSDTIGAIKKMVWKHARSEPLF
NVLSDPDAYVFTCINRTAEREELEDEQRRLCDVQPFMPVLRLVAREGDRVEKLINTQISL
LLGKGLHEFDAQKNHEVAEFRTKMRSFCEEKAQDRQRLPWHQWMEYNFPCDLEPFSRAAQ
SGKSRSVKKIFINVKFEASEESFMLQLDPQDMPVVLMRSALKKKATVFRPVKQEKPEDYT
LQVNGRWEFIYGKNPLCQFKYIFSCLYGGQTPHLTMVHHSTITKYQEEQGTLSSQVSKSR
SLSKPPPLPLKKQNTTSLWSIHEPFYIHLLQGSRVNADESMKLVVQAGLFHGSELLCKVV
TSSEVSVCSDPVWDQKLAFEINLCDLPRMSRLCFALYGVLEKTKKQRSTKKKKKADCPLA
WVNTMVFDYKDQLKTGEFLLSTWPSAPDDKGDLLNPMGTVERNPNIDSTAGLLIRFSNFR
PHPLCYPPLEKLNEAERNGEKISASKEEHQKLKEIVDNKNHTEFFEDEKELLWKLRGEVR
AHYPESLSKLLLITKWNKHEDVAQMVCLLRKWPDLPALHALELLDYSFPDPHVRSFTIRC
LRKLRDDELFQYLLQLVQVLKYESYLDCDLTTFLLERALSNKKIGHFLYWHLRSEMHVSS
VSLRFGLILEAYCRGSIYHIKSLMKQNEALNKMKALNDFVKSGSQKSTSRSQITEDMKLC
IKQDTYVEALSDTVSPLNPNIILSDICTEKCKFMDSKMKPLWLMYKNKWVQADTVGIIFK
NGDDLRQDMLTLQMIQLMDILWKTEGLDLRMIPYGCLSTGNKTGVIEVVKSSDTIANIQR
NNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRENGQLFHIDFGHFLGNFKAKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREC
CEQAYKILCRNGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKF
NEALRESWKTKVNWMVHTFAKDNR
>A0A8C9JRR5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera tigris altaica|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINICDLPRMARLCFAIYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIKEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEVLKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A1S3MDV2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo salar|TrEMBL
MHVQKMVWRNASSEPLYGALSDADAYVFTCINSTAEREELEDETRRLCDVRPFMSVLRLV
AREGDRVEKLTNTQISLLIGKGLHEFDSQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQW
MEYSFSCDLEPCVSLAEPGGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPMILMRSAL
KKKATVFRSVRQEKPEDYTLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHST
IVKYQEEQGCLGSQVSKSRSLSKPPPLPVKKQNTSSLWSIEEPFHIHLLQGYRVNADEGM
KLVVQAGLFHGSELLCKVVTSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIE
KTKKPRSTKKKNKKADCPLAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTV
EKNPNVDSAAGLLIRFPNIRPHPLYYPHFDKLRDLEKNGGKVIATKVEHMKLKEIVDNKN
YTEFFEDEKELLWKLRGVVRERYPESLSKLLLITKWNKHEDVAQMVAFLQKWPDLPALHA
LELLDYSFPDPMVRSFTISCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALS
NKRIGHFLFWHLKSEMHVSSVSLRFGLILEAYCRGNIYHIKSLWKQNEALNKMKALNDFV
KSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLLSPLNPSIMLSEICADRCKFMDSKMKPL
WLMYKNKWVQGDAVGIIFKNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGN
KTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPDRDKLDQAIEEFTLSC
AGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFV
HVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLK
DSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDSRL
>A0A8D2F0Q8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Theropithecus gelada|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAMQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7L1ZBD6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leiothrix lutea|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQQAQYEPLFHMLSD
PEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLLIGKG
LHEFDSVQDPEVSDFRAKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGPGTGSLQ
IPNKNIFVNVKFQSGGESFTFQISPWEFPITLMNYAIKKQATVFRHETVQKPEDYTLQVN
GKCEYLYGNYPLCQFQVSLVCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKVPSKPP
PLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSSSEVA
VCSEPVWRQRLDFDIGICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAWVNVM
LFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHPVY
YPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQ
YPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLK
KLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPAVS
LRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCMKQ
ETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGD
DLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKS
NMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVR
ETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCER
AYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEA
LRESWKTKVNWLAHNVSKDNRQ
>A0A7L1ZFM7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leiothrix lutea|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEILLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDRHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNHIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNVWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>F6VXG1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus tropicalis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMVVVLECLREATLVNIKHELFKEARKYPLYH
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVVEPVGNREEKILNREIGFA
IGMPVCEFDMVKDSEVQDFRKNILNVCKDSVELRDANGPISRALYVYPPNVESSSELPKH
IESKLDKGQIIVVIWVIVSPNNEKQKYSLKINHDCVPEHVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKDSLYSQIPVD
VFTMPSYSRRISTAAPYMNGEASAKSLWAINSTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGVEPLCDNVNTQRVPCSNPRWNEWLLYDMFIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVSGSNPNKETPCLELEFDCF
SSPVKFPDMTAIEDHANKVLEREMGYNYSHSGLSNRIVRENEVRESDKEQLKAISNRDPL
SEITEQEKEFLWSHRLYCRNIPEILPKLLLSVKWNCRDDVSQMYCLLKEWPAIRPEQAME
LLDFNYPDRIVRSFAVSCLEKYLTDDKLSQYLIQLVQVMKYEQYLDNHLVRFLLKKALVN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSKQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMKRPDFMDALQGFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSEMLFLNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRCSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGETYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDNGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGIQECTKTRDFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKHL
>A0A8C9F4M9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pavo cristatus|TrEMBL
MNCLLWKQAHTYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTR
NCDPGEKLDSKIGVLIGKGLHEFDALQDPEVNDFRSKMRRISEEKIQSLVGLSWMDWLKH
TYPPEQEPVVPENFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTI
HGKEDEEIDPADYVLQVSGRLEYVFGDHPLIQFQVLLLKIYPSWISSLKCNKNGSFHETF
NKCFNGLLYQIVFLSSYFNCNLIVFFLKQLQALLQIWPKLLPREALELLDFNYPDQYVRE
YAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQMLFWHLRSE
IHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAMKQSKAKGKDA
MHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCKYMDSKMKPLWIVYNNKMFGGDLVG
IIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLATGDHSGLIEAVSGSETIA
DIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRATEEFTLSCAGYCVATYVLGIGDRH
SDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGR
FRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLKVKMRSTAQHDVSIILV
CEFGFQDEQFLVYFNVSQDFHEVLKAFFFVCVE
>A0A7L0M7Q6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amazona guildingii|TrEMBL
MELEDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAANCTVEQMKAQIWMRALEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQNPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKVKVSIDDT
PDIILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFSISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDPKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKESSMAISIVLDKYCHPIALPKHRITSD
PQGDRIRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEIWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C9FRX9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pavo cristatus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELITIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAIEVSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDLFPLVLSLLDCRALHMLLTRLLCIFQAVKFEPYH
DSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLHDFM
KQVQVIELLHKVTMEIKSVSAEKYDNALGRFYVFQLFQKLLLLIEKCKVMASKKKPLWLE
FKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGN
KIGMRSHCN
>A0A8C3MV67|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geospiza parvula|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSSLPLPLPPKKRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLCK
TVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKYQ
TIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMERD
PLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPRE
ALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERAL
GNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSL
IKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKP
LWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATG
DHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLSC
AGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFI
HVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A480L774|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A250YLU7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Castor canadensis|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPMLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRIPNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQSLAEQPEDYA
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPTPQVQKPR
TKPPPVPAKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMVRLCFALYAVVEKTKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDDKGELLNPVGTVRSNPNTESAAALVICLPEVAP
HPVYYPALEKILELGHHEERGRITEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLLMEAYCRGSTHHMKVLMKQGEALSKLKSLNDFVKVSSQKTTKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYGGEEAGSAGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A341CQ83|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neophocaena asiaeorientalis asiaeorientalis|TrEMBL
MELETHEQHVVLREDNRRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLSPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRLAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRVAEVAGRDTKLYAMHPWVTSKPLPECLLKKITNNYIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIRNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDHK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKAEDHGSINADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCSFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTMDVKSLSAEKYDVSSQVISQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIERCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSRHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A1A8KPU6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius kuhntae|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLDCLRETPLISIKQQLFVEARKFPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDSEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKTRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIVVGRLPHLMLVSKDSLYSQLPAS
GYITPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYINVNIRDIDKIYVRT
GIYHGGEPMCDNVNTQRVPCSHPRWNEWLTYDLYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYSYCHGLSSRLACDSTVSASDAEQLRSLCSKDP
LYELSEQEKDFLWRHRHYCINIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMESESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKVQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEGYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQTFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A6J1TVR2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Notechis scutatus|TrEMBL
MPPAMADILDIWAVDSHIAGDSSVSVDCLLPTGIYISLDVPRDATICHIKQLLWKQAHSY
PLFHLLLEIDSYMFSCVNQTAVREELEDETRRLCDIRPFLPVLQLITRSCDPGEKLDSKI
GVLIGKGLHEFDALQDPEIKEFRIKMRQISEEKMQSLMGLSLMNWLKRTYPPVLELAVQD
NFQDKLYGGNIVVAIHYENCQDVFSFQVSPNINPIKLNELAIRKWLTIHGKEDEEVDPYG
YVLQVNGKLEYVFGDHPLIQFQYIHCCVINRALPHLTLIECSTIKTMYEQEMIAIEVAIN
RKSNNLPLPLPPKKKRLTQSVWEIVQPFKILLVNGSKLNTEETAKVHIRSGLFHGNELLC
KPIVSSEIAGRNDHVWNEPLEFDINVCDLPRMARLCFVVYAVMDKMKNKKSAKALNPSKY
QTMRKAGKVHYPVAWVNTMVFDFKGQLKTGDLLLHSWSSFPDELEEMLNPMGTVQTNPYS
ENATTLQIRFQEYSKCPIYYPPFDKILEKAAEIARNSDCSGMAGRGGKKFFIELKEIMER
DPLSQLCENEMDLIWTLRFDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPR
EALELLDFNYPDQYVREYAVGCLRQMSDEELAQYLLQLVQVLKYEAFLDTALSRFLLEKA
LANRRIGQMLFWHLRSEMHIPAVSLQFGVILEAYCRGSITHMKVLSKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDTMHTCLKQSAYKEALSHLQSPLNPSVLLSELCIEKCKYMDSKMK
PLWIVYSNKAFGADLVGIIFKNGDDLRQDMLSLQMLRLMDLLWKEAGLDLRLLPYGCLAT
GDYSGLIEVVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNTGEDLDRAIEAFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQCCEEAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKNDDEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>H9ZA48|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca mulatta|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPFSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDIHICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A6P7ZAD5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcaecilia unicolor|TrEMBL
MELENYEQPVVLREENKHRRRRMRPHSAASNLSSTELISIEFFLPTVSKLTKTQDTLVLE
IAGNCTVEQMKAQVWMRAIETNLNSDFYHKLTPDHFLLHYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGKIHIVEKQKMTEEVLEFQKQLNYLIGYDVTDVSNVHDDELEFTRRRL
VTPRVIELASRDPRLYSMDPWITSKPLPEYMFKKITSSNVFIVIHRGTTSQTIKVSIDDT
PNMILQTFFTKIAKKKSLLDIPEDHSELDFVLRVCGRDEYIIGDTPIRDFHWIRECHKNG
EEIHLVLDTPPDPALDEVQKEEWPLVDDCTGVTGHHEQLTIEGKDHEKVFTISLWDCNRK
FRVKVIGIDIPVLPRNTELMVFVEANIQHGQQLLAQRRTTCKPFTEEVLWNTWLDFDIKI
KDLPKGALLNLQIYCGKSPSLTTKTNVQPHDTLSSDSKCKNQLLYYVNLLLIDHRFLLRQ
GDYVLHMWKIPGKGEEQGSINADKLTSATNPDKETSMAISIVLDRYCHPIALPKHRTVSD
LEGDRTRTEMPNQLRKQLEEIIATDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLASVK
WGHQETVAKTYQLLAKKEAWDRSSLDVGLTMQLLDCNFPDENVRAMAVQKLESLQDDDVL
HYLLQLVQAVKFEPYHDSALAKFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRFAVLL
EAYLRGCGKAMLHDFMKQVQVTEMLHKVTMEIKSISAEKYDVTSQVITQLRQKLDKMQSS
NFPESFRVPYDPGLRAGTLVVEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAEALDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEVLNQWLKEKCPVEEKFCASVERFVYSCAGYCVATYVLGIGDRHNDNIMITES
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSQHFHKFEDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGRSEDEAKRHFLDQIEICRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>F7CM33|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callithrix jacchus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGTIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDGLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
ISPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIILVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEVSGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKAKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6J3E5Z8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aythya fuligula|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPYCTSSNLSSMELIAIEFILPTSNKHTKIPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYQAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PEMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHDSPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A672KVB4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDVSGPHSRALYVYPPNVESSPELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTETDIEQLRQLSNRDPL
SEITEQEKDFLWRHRQYCVNIPEVLPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A8C9NWD2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Serinus canaria|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLCK
TIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKYQ
TIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMERD
PLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPRE
ALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERAL
GNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSL
IKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKP
LWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATG
DHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLSC
AGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFI
HVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>W5KR52|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDVNGPHSRALYVYPPNVESSPELPKH
IFGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKIYVRTGIYHGGEQMCDNVNTQRVPCSNPR
WNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVAGKMA
LNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYFSSPVKFPDMATIEDHANWIISR
EMGYNYCQSGQSSRLARDHIITEADIDQLRQLANRDPLSEITEQEKDFLWRHRQYCVNIP
EILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKY
LTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTNQRIGHFFFWHLKSEMHNKTVSQ
RFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRP
DYMDALQSFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFK
NGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQC
KGGLKGALQFNSSTLHQWLKDKNKGETYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIM
VKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQ
EMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQEALDYFMK
QMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A8B9H1X6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MEQHISDDEPPAVPREENNKRRRRKMKAFTSATSVPVDHLVMEFVLPTTNKTTKNPDTVQ
LEVLGNWTVEQVKAQLWLRAVATNLCPEFYQKFSPDHTILLYQKKGSWCEIYDKHQVFQT
LDCIRYWKALKKEIGKIHLVLRPQSSEESVQYQKFLNHLIGYDVTDVSNVHDDELEFTRR
KLLTPRKIELADRDPKLYSMDPWITTKTLPDYLLSKITNGYILLVIHIGTSSQTIKVSID
DTPVQVLQSFFTKIANKRALLGIPEEVNESDFVLRVCGREEYIYGNYAIKDFHWIRQSLK
SGEEIHLVLEPPPNPEQDGVQKEDWSQVDDCTGVAGTHEQLTIDEKDHEKVFTISLWDCN
RKFRVKILGIDIPVLPRNSELIVFVEASVFHGQQQLAYERTSPKPFTEEVLWNTWLEFNI
KIKDLPKGARLNLQVSCSKAQTQTSRDSAVHDCKTKSRLLYYVNLLVIDHRSLLRQGEFI
LHMWKMPEKSAEDSSVNADKLTSATNPDKTSSMAIAVLLDKYCYPVALPKSRDSRDSSDM
EGERGKREMPNHLRKQFEQIVATDPLHPLSSEDKELLWHFRQDCMRHPSAYPKFLGSVKW
GKQEDVMATHQLLERSTTWDRSPLDVGLAMQLLDCHFSDAKVRTMAVRKLETLGDDDVLR
YLLQLVQAVKFEPYHDSALAQFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILE
AFLRGCGEVMLQDFSKQVEITEALQKITREIKAMSAEKYDVSPQVVLQLRQKLDSLQSSG
LPESFKVPFDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDL
RQDMLILQILLIMESIWETESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGN
TGAFKDEILNQWLRDKCVSEEKYQQAVDRFVFSCGGYCVATYVLGIGDRHNDNIMITESG
NLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTTGKKSSPNFLKFQFAVYMHDV
CVRAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGCSEDEAQKHFLDQI
EICRDKGWTVQFNWFLHLVLGIKQGVEKRSA
>H3CQV3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tetraodon nigroviridis|TrEMBL
TMPPRPSSGELWGMHLMPPSILVECLLPNGMILTLECLREATLITVKHELFKEARKYPLY
HLLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGF
AIGMPICEFDLVKDPEVQDFRRNILNVCKEAVDFRDCNGPHSRALYVYPPNVESSPELPR
HIYNKLDKGQIIVVIWVIVSTSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQL
KMCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPM
DVFTMPSYARRISTATPYMNGETATKALWTINGSLRIKILCATYVNVNIRDIDKIYVRTG
IYHGGEQLCDNVNTQRVPCSNPRWNEWLSYDMYIPDVPRAARLCLSICSVKGRKGAKEEH
CPLAWGNINMFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEH
FGCPVKYPDMTIIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDADNEQLRQVCTRDP
LSEITEQEKDFLWRHRQDCLNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIRPEQAM
ELLDCNFPDPMIRAFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKRALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLL
KQEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPL
WLNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A2K6RRD9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinopithecus roxellana|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAIYAVLDKVKTKKSTKNI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIMLHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGYWVIYKGKSDEELSQYLLQLVQVLKYEPFLDCALS
RFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALN
KLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCK
YMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRML
PYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRA
IEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVP
FILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTS
VKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K6ZJ76|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothoprocta pentlandii|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHMFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTSLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
LPGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSALDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVLL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITEA
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L3SSA5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rissa tridactyla|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSTNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFRKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A5F8AQY8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca mulatta|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYTL
QVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRA
KPPPIPAKKPFSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSS
EVSVCSEPVWKQRLEFDIHICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWA
NLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAPH
PVYYPALEKILELGRHSECVHVTEEELQLREILERRGSGELYEHEKDLVWKLRHEVQEHF
PEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLRK
LTSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQ
TKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGS
GGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLR
SDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLG
IGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNS
EKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEE
ALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C7MGQ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRVKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQLSKS
RSLSKPPPLPVKKQNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKV
VTSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCP
LAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIHFPN
IRPHPLYYPHFDKLRDLEKNGGKVIATKVEHMKLKEIVDNKNYTEFFEDEKELLWKLRGV
VRERYPESLSKLLLITKWNKHEDVAQMVTFLQKWPDLPALHALELLDYSFPDPMVRSFTI
RCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHV
SSVSLRFGLILEAYCRGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKL
CIKQEAYKDALSYLLSPLNPSIKLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIF
KNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQ
RNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDN
IMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRE
CCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVK
FNEALRESWKTKVNWMMHSLAKDSRL
>A0A8C4AXU5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPTMMDVLDLWAELGEVEHVSVDFLLPTGLYIQMEVPREATIQHIKQLLWKEAAGYPLF
TLLGAMEGHMFECVNQTAVHEELEDETRRLCDVRPFLPVLRVVTRSGGHNERLLDSKIGV
LIGKGLHELDSLQDQEIKDFRTKMQQISKEKIQRIQVMSWEEWLRTHFSPQLEVGQVDGM
IEKLCEDGIKVTMHYDQSQVCTVRTLLELALRKWANTHGHNNSSCLSDYILRISSKLEIL
YYVLGICLIFVCVQYIRECLLAQESPHLTVMHSSVLRGMFERELGCIASVCGHKQSNAPL
PLPPKKRPPSVSTCSQFKITLVRGIKVNTEESAKVYVRAGLFHGAELLGKPAVSSDSSGR
LEHLWNTTLEFDVAVSDLPRMSRLCFAIYAVMDKVKKQPKSIKTPHSKYQTIRKHYPIAW
VNTMVFDYKGLLKTGDVVLYCWSSFPDELEEMLNPIGTVQTNPYTENATAIHITFPEYSQ
ISVIFPPFDKRLSPHGSECLHHSYNKDSLKEIMDREPLSQLCENEKDLIWTLRYDCRENF
PQSLPKLLLSVKWNKHEDMAQLQALLQIWPTLSHRDALELLDFNYPDQYVREYAVNCLRD
MSDEELSQYLLQLVQVLRYEPYYDCALSRFLLERSQLNRNIGHFLFWHLRSEMHMPAVSV
QFALILEAYCRSSIPHIEVLKKQVEALNKLKAVNALVKTGAVKSKARTKDSHLKEAMLTC
LRQSGFTETLSDIHSPLNPSVLLAEVNVDRCKYMDSKMKPLWIVYNNKLLGGETLGIIFK
NGDDLRQDMLTLQILKLMDLLWKEANLDLSDTLERAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTANTEKFGS
FRQYCEEAYLVLRRNGNLIITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQF
RQKFDEALRESWTTKVNWMAHHIAHAS
>A0A8C0FRN9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
MNFCLCFNSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIK
QLLWKQAHAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNC
DPGEKLDSKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTY
PPEQEPVIPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHG
KEDEEVDPADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQ
EMIAIEAAINRKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRA
GLFHGTELLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKK
STKAMNPSKYQTIRKAGKVHYPVAWVNTMVFDYKGQLRNGELVLHSWSSFPDELEEMLNP
MGTVQTNPYTENATALHIRFQEYSKQSINYPPFDKILEKAAEIARSSDNAAMAGRGGKKF
HIVLKEIMERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQAL
LQIWPKLLPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDC
ALSRFLLERALANRRIGQMLFWHLRSEVHIPAVSIQFGLILEAYCRGSVAHMKVLAKQVE
ALNKMKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVE
KCRYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDL
RILPYGCLATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDL
DRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRE
RVPFILTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPE
LTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>F1MYM3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos taurus|TrEMBL
MCFYFMMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISCIKQMLW
KQVTNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPEL
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHSLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMVAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEPLEFDINTCDLPRMTRLCFAVYAVLDKVKTKKSTKTM
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPHALPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKTEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6J3E5J1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aythya fuligula|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GLLHTPTKNIFVNVKFQSGGESFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANTPKMS
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPNVAS
HPVYYPSFEQLLELGRNGEPPRTAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDNELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A851CVL3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calyptomena viridis|TrEMBL
MELGDPEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQVWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSAKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDSKGKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPRAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C0FLU7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQVHKALWNLPMNLYLCFPSQSVWDISNPFKIILLKGNKL
NTEENAKVHVRAGLFHGTELLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFA
VYAVMDKMKTKKSTKHYPVAWVNTMVFDYKGQLRNGELVLHSWSSFPDELEEMLNPMGTV
QTNPYTENATALHIRFQEYSKQSINYPPFDKGRGGKKFHIVLKEIMERDPLSQLCENEMD
LIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLCIVLLHETEKLGDTLAVETNLSLLD
LYSVTDCFYVPHSSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQMLFWH
LRSEVHIPAVSIQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAMKQSKAK
GKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKPLWIVYNNKMFGG
DLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATGDHSGLIEAVSSS
ETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSCAGYCVATYVLGI
GDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTE
KFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEA
LKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3P9K9E1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MKIAELWFVCRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHHLLQEETCY
IFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEF
DLVKDFEVQDFRRNILNVCKDAVELRDANGPHSRALYVYPPNVESSQELPKHIYSKLDKG
QIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQG
KYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYSQLPTDSFVMPSYC
RRISTATSYMNGEAAPKSLWTISGGLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQMC
DNVNTQRVPCSNPRWNEWLNYDMYILDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNIN
LFDYNHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEHFSSPVKYPD
MNAVEEHANWTISRELGFNYNTSGQSNRVARDHALTDSDSEQLKQLSNRDPLSEITEQEK
DFLWRYRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAMELLDCNYPD
PMVRHFAVRCLDKFLADDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFF
WHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQ
KVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDI
MSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLI
EVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNRGEMYDMAVDLFTRSCAGYCVAT
FILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGS
QECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLAL
EKGEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>H0XCZ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Otolemur garnettii|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSCNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSCPLQLEPSARGWGG
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYA
LRVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQSQKPR
TKPPPIPMKKPFSVSLWSLEQPLCIELIQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVNVCSEPVWKQRLEFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLYMWPSAPDEKGELLNPAGTVRGNPNTESAAALVIFLPEVAP
HPVYYPALEKILELGRHSECGRITEEEQLQLREILERRGSAELYEHEKDLVWKLRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTRFLLDRALANRRIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALGKMKALNDFVKVSSQKTTKPQAKELMHLCMR
QDAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEQAGGDGCVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
EKAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A3B3HRG4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MPPAMTDLVDIWAAHSPLDGQAPVHVTMDFLLPTGIYIQMEVPREATIQHIKLLLWKQAK
SFPLSSFLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVFRLVTRNCGRAERLLD
SKIGVIIGKGLHELDGINDQEVKDFRSKMQRLSEERMQRVQMMSFTEWLQACFSPQLEPS
AGTAIADGANDWPADLKVIIHFDQSQDSTSLKVPSSCTPSVLIEIALKKWQTTHAPEEET
NKDKHILRVSQCLDFLCGDHPLIQYKYIRSCLQAKESPHLTLVHINAVKTIFDKENAAIG
AVVSRKSSNPPLPLPPKKRAPTQVQTCVWDVSRPFKVVLVKGSTVNADENAKVQVRAGLF
HGTELLCKPAVSSESSGRSNHSLENNTLEFEISVCDLPRMTRLCFAIYAIMEKVKKKSYK
NPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDMILHCWSSFPDELEEMLNPIGT
VRINPYPENATALHIHFPDYGPHPIVFPPFDKILEKAAEIAGSSDSTPIGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRLDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVSCLRDMSDEELLQYLLQLVQVLRYEPYYDCALTH
FLLERAQKNRKIGHFLFWHLRSEIHMPAVSIQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNTRSKTKEAMLTKEAMITCLKQSGYSEALSDLHSPLNPNVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLMSSDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLVLRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKSDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C4S1X7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Erpetoichthys calabaricus|TrEMBL
MPPGMYFILENWEEEASQDVQIDFLLPTGIYLSLSVSRNSTIEAIKEIIWNKAKTEPLFC
ALNDPDNYVFMCINHTAEREEIEDEQRRLCDVRPFFCVLQLVGREGNRIEKQINSQISLL
IGKGLHEFHSLKNLEVNDFRTKIRPFCEEKAMDRQRLTWYPWMMCNYPFELEPYPKLPET
GVLKSRSSKKFMVNVKFENSEESFTLQISPQDVPLTLMQSALKKRAMVFREPKQDKVTDY
VLKVNGRLEFIYGDYPLYQFKFICACLHASTTPHLTMIHCSTIKSMQDEQEGFSVQVSKI
CSGPKRPPLPPKKQDMSFTIEEPFQIHLLQASKVNVDDGMTLIVQAGLFHGSEMLCKTVT
SNDVQFSSEPAWDNKLVFDINVSDLPRMTRLCFALFGAVERTKKPRSTKKKLKKADCPLS
WVNTMVFDYADRLKTGELTLYAWPSTLDDKVDLLNPMGTVDSNPNIESTVSLTIFFPNFR
TQPIYYPPTEKIIQMGMNGKASRASPEELQKLKEVLENKNYTEFFEDDKELLWKLRYDIR
ELYPENLAKLLSITKWNKQEDVAEMIYLLQHWPDLSPLHALELLDYTFPDRSVRAFTIRC
LRKLSDDELFQYLLQLVQVLKYESYLDGDLTRFLLERALANRKIGHFLFWHLRSEMHVPS
VSFRFGLILEAYCRGSTPHMKILAKQNEALNKMKSLTDFVKSSSQKTTKNITKEVMQFYM
KQDAYLEALKDLLNPLNPNLILSDLCVEKCKFMDSKMKPLWLVYNDSFQSGSIGIIFKNG
DDLRQDMLTLQMIKLMDVLWKQEGLDLRMIPYGCLSTGYKTGLIEVVIDSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RQNGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNDSEKFERFRSYCE
TAYKILCRNGVLFVNLFKIMQASGLPELSSSKDIQYLKDSLALGKPEEEALKNFKVKFNE
ALRESWKTKVNWMAHNVAKDNR
>A0A8C9D2G0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera leo|TrEMBL
MELDNYEQPVVLREDNRRRRRRMKPRSTTASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVATDFYRRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQIHVVQRHAPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCSKAPVLAGKTSAETPSSESKGKTQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTDQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKEATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8C5EWF7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
MENNLKQLESYTTGSPELLATSLTWFHKALIHKLKIPSVLLHSRSLWLRWCRLPLAMPPA
MTDLLDIWAPHSPLAGHTLAQITVDFLLPTGIYIQMSVPREATIQHIKLLLWKQAQMFPL
FPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLDSKIG
VLIGKGLHELDAINDQEVKDFRSKMFRISEERMQQVQMMTCTEWLQACFSPQLEPAASAI
ISDGVSDRPTDLKVTIHFDQSQDSASLKVSWSCTSAELMELALRKWLSTHGPEEDACRGQ
YVLRVSHCLEFLCGDHPLIQYKYIRSCLQAKESPHLTLVHTRTIQAMFDKEISAIGSVVS
RKTSNPPLPLPPKRRVPTQVQTCVWDVSSPFKIVLVKGSKVNAEESAKVQVRAGLFHGTE
LLCKPSVSSESNFRSDHTWKDSTLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNAH
INKYQTIRRAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQT
NPYTENATALHIHFPEYLSHPIIFPPFDKILEKAAEIARASDCVSIGRGGKKFHIELKEI
MERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQVLLQIWPKL
SPRDALELLDFNYPDQYVREYAVGCLRDISDEELLQYLLQLVQVLRYEPYYDCALTHFLI
ERAHGNRVIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKS
VNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSIQLSGINVER
CRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLR
VVPYGCLATGDRAGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALE
RAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRER
VPFILTHDFIHVIQQGKTGYTEKFCNFRQNCEDAYLILRKNGNLFITLFALMLTAGLPEL
TSVKDIQYLKDSLALGKSDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7K8F6V1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Struthidea cinerea|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKANLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K8FK04|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Struthidea cinerea|TrEMBL
DSIMPPAMTDSLDIWAVDSQIGADGSVSVDFLLPTGIYINLDVPRDATISQIKQLLWKQA
HSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETQRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHAYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTTVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGHLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C5I7M6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
QCKLQQPHGGCCMVWKNARNEALFNGLGDPEGYVFTCINQTAVREELEEESRRIRDVRPF
MCVLRLVAREGDRVEKLTNTQISLLIGKGLHEFEAQKNHEVNEFRSKMRSFCEEKAQKRQ
GLPWQQWMEYSFPCDLEPCSAKSKNKKKIFINVKFEASDESFMLQQEPQDLPLALMRSAL
KKKATVFRSLRQEPEDYTLQVNGRWEFIFGKHPLCQFKYIFSCLRNDENPQLTMVHHSTI
SKYQEEQGRMCNHIYRSCAMSRPPPLPQKKQNTSSLWAINKPFNIHLLQGSRVNADEGMK
VSVRAGLYHGSELLCKVVTSSEVTVCSEPLWDQKLDFDINVADLPRMSRLCFALYAIIEK
AKNSSTLWILHVVVKLTWTCLCFQDCPIAWVNTMVFDHKDQLKTGEFLLSTWPSVPDDKS
ELLNPMGTVEKNPNVDSAAGLLIRFPNILPHPLYYPPLDKVLYTKLKEIMDNKNHTEFFE
DEKELLWKLRTDIRDCYPESLSKLLLITKWNKREDVVQMVSLLESWPELPAIHALELLDY
SFPDPAIRSFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCVLTTFLLERALANRRIGH
FLFWYLRSEIHVASVSLRFGLILEAYCRGNIHHMKVLTKQNQALVKMKALNDFVKSGSQK
MTVEDLRLCVKQESYMEALSDLLSPLNPSVILAEICADKCRFMDSKMKPLWLMYRNPWPH
ADMLGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKN
SDTIANIQLNSSTSAATAAFNKDALLNWLKSKNPEDKLEQAIEEFTLSCAGYCVATYVLG
IGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGKTNNS
EKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEDE
ALKNFKVKFTEALRESWKTKVNWMMHSLAKDNRP
>A0A852C1I3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ramphastos sulfuratus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEIILLE
IAGNYTVEQMKTQVWMRAIEMSQSTDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSEMDFVLRICGRDEYITGETRIKDFQWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVVWNIWLEFDIKI
KDLPKGALLNLQMYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNILLIDHRFLLRT
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPVALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIITTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTTLSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKEKCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A2U9B0Q3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNLESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKVGFCS
SSVALCLCSSRPTFSSYCPVVWNEWLTYDIYLADLPRSARICLSICSVKGRKGAKEEHCP
LAWGNVNLFDYKDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFSWFN
QTVVFPDEQQIEEHANWTISRELGYNYCPGLTSRLACDVSVSAADAEQLRCLCSKDPLYE
LSEQEKDFLWRHRHYCVNIPESLPKLLMSVKWNSRDEASQMYCLLKEWPLMEPESALELL
DCNFPDPMVREFALRCLVKGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQR
IGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQE
KKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLN
WENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRTREEEDQGEL
ECHHDNSDGTNINNNNNQRKTVCPGVGEHPLQYNYTFWFSRRTPTRPASSQSYEQNIRQI
GIVASVEQFWKFYSHLVRPGDLSGHSDFHLFKEGIKPMWEDDFNRSGGKWIIRLRKGLAS
RFWENIILAMVGEQFMVGEEICGAVVSIRFQEDILSIWNKTSNDQTTTSRIRDTLRRVLN
LPANTIMEYKTHNDSLRY
>A0A852CUK5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ramphastos sulfuratus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETPENPEDYT
LQVNGKCEYLYGSYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWRQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAP
HPVYYPSFEQLLELGRNGEQLRAAAEDPEEKQQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGQVASLLLKQAIEEFTLSCAGYCVATYVLGIGDR
HSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFE
RFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKH
FRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A1A8JI67|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius kuhntae|TrEMBL
MPPAMTDLLDIWASHSPLAGHALEKITVDFLLPTGIYIQMDVPRDATIQHIKLLLWKQAQ
NFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRITEEKMQQAQVMTCTEWLQACCSPQLEPT
AVTLVTDGVNDRPADLKVFIHFDQSQDSTSLKVPMSCTPSELMEIAVKKWLTTHAPEDEA
YSRQYVLRVSQCLEFLCGDHPLIQYKYIRNCLQAKESPHLTLVHTSTVKIMFDKEMSAIG
AVVSRKSSNPPLPLPPKRRPPTQVQTSVWNVSKPFRIDLLKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSDSSGRSEHTWKNNTLKFELSVSDLPRMTRLCFAIYAVTDKVKKQKST
KNAHSSKYQTIRKAGKVLYPIAWVNTMVFDYRGQLKTGDVILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHPVIFPPFDKILEKAAQLVGVIEQPIGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVSCLHDMSDEELLQYLLQLVQVLRYEPYYDCPLTH
FLLERAQRNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSEALSDLTSPLNPSVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLMSGDALGIIFKNGDDLRQDMLTLQILRLMDLLWKESNL
DLRIVPYRCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQEGKTGNTEKFGSFRKYCEEAYLILRRNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKNDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>H2N969|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pongo abelii|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNP
TGTVRSNPNMDSAAALLICLPEVAPHPVYYPALEKLLGGMLLASRGWRPELLWMCLHAQD
SAPSRTIGVAMPCLGVLPRLVQAPGDAECSCLLQILELGRHSECVHVTEEEQLQLREILE
RRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQDALPAVSWPELPV
LSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDR
ALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K5BQM2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Motacilla alba|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQMLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSILDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A662YVI9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acipenser ruthenus|TrEMBL
MPPAMTDILDIWAVDSHLVNDACITVDFLLPTGIFIQMDVPREATLQHIKLLLWKQAQSY
PLFTFLGQMEAYMFECVNQTAVHEELEDETRRLCDVRPFLPALKLVTRNCGRAEKLLDSK
IGVLISKGLHELDALQDPEVKEFRAKMLRISEEWMEWLQCSFCPLLEPSVPDNILDKLHG
GQIVIAVRFDNSQIVSLKVSPHTSPSALTEQALRKWLTTHGKEEEEANSNNFVLRVSGRL
EYLFGDHPLIQFKYIRNCVTNNESPHLTLIDSCTVKEVFEKELSTIGAVVNRKSSNPPLP
LPPKRRATSQISTCVWDVMVPFTIVLVKGSKVNAEETVKVQVRAGLFHGTELLCKPAVSA
ETFGKNEHVWDKTLEFEINVCDLPRMTRLCFAVYAVMDKVKKQKSTKNIHAKYQTIRKAG
KVVQVRAGLFHGTELLCKPAVSAETFGKNEHVWDKTLEFEINVCDLPRMTRLCFAVYAVM
DKVKKQKSTKNIHAKYQTIRKAGKVHYPIAWVNTMVFDYRGQMKTGEIILHSWSSFPDEL
EEMLNPIGTVQTNPYTENATALHIKFPAYSRPTVFYPPFDKGRGGKKFHIELKEIMERDP
LYQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWNKHEDMAQLQALLQIWPKLSPRDA
LELLDFNYPDQYVREYAVHCLRDMRQSEIHMPAVSVQFALILEAYCRGSIPHIEVLKRQV
EALTKLKAVNELIKLGTIKSTKSKAKEAMMTCLKQSAYTETLSNLQSPLNPSVILSGLNV
EKCRFMDSKMKPLWIVYENKLLGGESLGIIIKNGDDLRQDMLTLQILRLMDMLWKEANLD
LRIVPYGCLATGDKSGLIEVVSASETIANIQLTNSNVAATAAFNKDALLNWLKEKNSGDA
LERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKR
ERVPFILTYDFIHVIQQGKTGNTEKFGRQVSFWFRQYCEEAYLILRKNGNLFITLFALML
TAGLPELTSVKDIQYLKDSLALGKTDEDALKQFRQKFDEALRESWTTKVNWMAHNVAKDN
RSAPAPTQGPLSGSANPETGGPPPPPNTTSNRRIQQSQAQVDEVVDVMRMNMEKVMERDT
KLSELDDRADALQAGASQFETSAAKLKRKNWWKNCKMMIILGGVCAIILIIIIIRDMRLL
YNTRASELQIKVPCVWPSNRKQRLCISRLLIHICTLKFITQAVLYIVREGVSAEQKQRYL
LSGIAF
>A0A673I9I5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYSMPLEAGSLE
NLIDKHEGVIKITMHYDQSQVLTELMDQALKKWQTTHGPEEDIGFRSDYVLHVSGKLEFL
FEDHPLNQCKVRYVARNGFESSNYIFQGFVNMVKIQHSTTYCFRAMCSLKFQLHTCVWKV
HSLFRINLVKGNKVNAEDAAKIQVRAGLFHGTELLCKTAVSSESSSRSEHVWNKTLEFDI
AVCDLPRMARLCFAIYAVMDKVKKPRSTKNTHLNKYQTIRNVLRKCLFFLCVADELEEML
NPIGTIQTNPYTENATELHINFPEYSTQPVVFPAFDKGRGGKKFYIELKEIMERDPLSQL
CENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELL
DFNYPDQYVREFAVYCLQDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERSQSSRKI
GHFLFWHLRSEMFMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFGT
IKTKTKQAHLKEAMMTYLCVCKYMDSKMKPLWIVYNNKLLEGDTVGIIFKNGDDLRQDML
TLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAA
FNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFH
IDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRK
NGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTT
KVNWMAHIVAHPS
>A0A673MVL9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQS
GKSHSGKKILVNVKFEGSEETFVLQQDPQDLPMFLKWNALRKKSTVFRSAKREKPEDYTL
QVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRTRA
QSKPPPLPLKRVRRHFYTGTRSLVVQAGLFHGSELLCKVVTSNEVSVCSEPVWDQKLVFD
IGVSDLPRMSCLCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFSL
STWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKLNELGMNGE
KVVATKEEHLKLREIVDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHE
DVAQMVGLLRKWPELPAIHALELLDYSFPDPHVRSFTIRCLRILRNDELFQYLLQLVQVL
KYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSIFLI
KSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSI
VLCELCADKCKFMDSKMKPLWLMYKDKYDHVGIIFKNGDDLRQDMLTLQMIQLMDVLWKT
EGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKN
PGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSKF
GINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMKA
AGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSFAKDNR
>A0A673MVK4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQS
GKSHSGKKILVNVKFEGSEETFVLQQDPQDLPMFLKWNALRKKSTVFRSAKREKPEDYTL
QVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRTRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSCLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGMNGEKVVATKEEHLKLREIVDNKNYTEFFEDEKELLWKLREEVRQ
RYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHVRSFTIRCL
RILRNDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSV
SLRFGLILEAYCRGSIFLIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIK
QDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKDKYDHVGIIFKNGDDL
RQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNS
AATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRET
GQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAY
KILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKVNWMMHSFAKDNR
>M7B5W3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelonia mydas|TrEMBL
MTDILDIWAVDSQVGADGLISVDFLLPTGTYINLDVPRDATICHIKQLLWKQAHSYPLFH
LLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKIGVLI
GKGLHEFDALQDPEVKEFRSKMRRISEEKLLSLVGLSWIEWLKHSYPPEQEPSIPENFQD
KLYGGNLVVAIHFDKCQDVFSFQVSPNINPVKLNELAIRKRLTIHGKEDEVDPYDYVLQI
SGRLEYIFGDRPLIQFQYIHKCVMNRTLPHLTLVECCSIKKMCEQEMIAIEAAINQKSSN
LPLPLPPKKTRTVTLTQSVWDISNPFQIMLLKGNKLNTEETAKEAVSHGIVAFSKDTLYY
NINCSDILDELEEMLNPMGTVRTNPYTENATALHIKFQEYSKLPIYYPPFDKILEKAAEI
AKSSENAGMAGRGGKKFYIELKEIMERDPLTQLCENEMDLIWTLRYDCRENFPQSLPKLL
LSIKWNKLEDVAQLQALLQIWSKLPPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQ
YLLQLVQVLKYEPFLDCALSRFLVERALANRRIGQMLFWHLRSEVHIPAVSVLFGVILEA
YCRGSIAHMKVLSKQVEALNKLKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSN
LQSPLNPSVILSELYVEKCKYMDSKMKPLWIVYNNKMFGGDLFGIIFKNGDDLRQDMLTL
QILRLMDLLWKEAGLDLRMLPYGCLATGDHSGLIEAVSASETIADIQLNSSNVAAAAAFN
KDALLNWLKEYNLGDDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHID
FGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHG
NLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKV
NWMAHTVRKDYRS
>A0A4W6FP98|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPEGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNIINVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKPLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFISPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A4W6FZL6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MQTQVSDEEPKYLREETRRRRRKKAITSSSSASMDQISVEFILPTVARGGNSPDSLQLDV
AGNWTVEQVKAQVWLKAVTSNLCPEFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDC
IRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLL
TPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVSNSHILVVIHIGTASQTIKVSIDDTP
AQVLASFFTKTANKRVLLGIPDNMCEADYVLRVCGREEYLYGDKPLQNFNWIRQCLKNGE
EIHLVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDGKDHERVFTISMWDCNRKF
RVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKIK
DLPKGARLNLQVVCGKQPQTPNSKGSSYQDNTSRLLYYVNLLLIDHRSLLRQGEFILHMW
KMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDVAAVGE
DVEGGERGQREMPNHLKKQFAAIVSTDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGS
VRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDD
VLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAV
LLEAYLRGCGEAMLQDYRKQVEMTEALQKVTREMKAMSADKYDVTAQVVFQLRQKLETLQ
SSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDG
DDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSV
VGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMIT
ESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVK
AYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEIC
REKGWMVQINWFVHLVLGIKQGVEKRST
>A0A7L2WW58|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pandion haliaetus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLPSLESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKREVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIESLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
RLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A803WB52|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ficedula albicollis|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQDPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAIYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLRSGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKLQALLQIWPKLLPREALELLDFNYPDQYVREYAVG
CLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQMLFWHLRSEVHIP
AVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAMKQSKAKGKDAMHTC
LKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKPLWIVYNNKMFGGDLVGIIFK
NGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATGDHSGLIEAVSSSETIADIQL
NSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQY
CEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKF
DEALRESWTTKVNWMAHTVRKDYRS
>A0A7K9NC42|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Edolisoma coerulescens|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLGWAAWMEYNFPLQLEPVAKGLGT
GSLQIPTKNIFVNVRFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQRPEDYT
LQVNGKCEYLYGNYPLYRFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQNNCITSPPKAA
CKPPPLPKKKPNYGSLWSLEQPFHIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPHTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETAGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A669D2M7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRCKMFRISEERMQQIQMMTFSEWVQACYSPQLEPA
AVTAITAGVNDAPADLKVIIHFDQSQDSASLKVSLSCTPNELMEQALKKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKDTPHLTLVHTSAVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRRAPTQVQTCVWDVPKPFRIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSNESSGRSEHTWKDNTLEFEISVCDLPRMTRLCFAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHPIVFPPFDKVTQHSIGRGVKKFYMELKEIMERDPVS
QLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALE
LLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQRNR
QIGHFLFWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQVEALSKLKSVNELIKL
GTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDINVEKCRYMDSK
MKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCL
ATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTH
DFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQ
YLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>I3K1C8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MEKKQQIQVSDEESQVPREESRRRRRKKAITSSCSNSMDQITVEFVLPTAARGGSGSDTL
QLDVAGNWTVEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQ
TLDCIRYWRALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRRIELSERDPKLYSMDPWVTCKPLPEHLLSKINNGHILVVIHIGTASQTIKVSI
DDTPTLVLVSFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCL
KNGEEIHLVLEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDC
NRKFRVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFN
IKIKDLPKGARLNLQVICGKQPQIPNSKGSSYQERKTKSRLLYYVNLLLIDHRSLLRQGE
FILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRD
WAVGGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHECMRVPRAY
PKLLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLE
TLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSKHY
QQRYAVLLEAYLRGCGENMLQDFRKQVDMTEALQKVTREIKTMSADKYDVTPQVVFQLRQ
KLENLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADSTTLSKDPIG
IIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIA
NIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHN
DNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKF
QDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLL
DQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A093GNU8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dryobates pubescens|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEIILLE
IAGNCTVEQMKAQVWMRAIEMSQATDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSEMDFVLRICGRDEYITGETRIKDFQWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVVWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNILLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPVALPKHRITSD
SQGERTRAEMPNQLRKQLEEIITTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEVVSKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTCQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKEKCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSVHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L2MBM1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hippolais icterina|TrEMBL
MPPGIFCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWQHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPVTLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVAVCSEPVWRQRLDFDIGVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQ
>A0A7M4E9U5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crocodylus porosus|TrEMBL
MPPTVTDILDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSRI
GVLIGKGLHEFDALPDPEVKEFRTKMRRISEEKNQSLVSLSWMDWLKHTYPPEQEPSIPE
NFQDKLYGGNLVVAIHFDNCQDVFSFQVSPNINPIKLNELAIRKRLTIRGREDEEINPSD
YVLQVSGRLEYVFGDQPLIQFQYIRNCVMNRTLPQLTLVECCSIKKMCDQEMIAIEAAIN
RKSSNLPLPLPPKKTRTATLTQSVWDISNPFKIILLNGNKLNTEETAKVNVRAGLFHGTE
LLCKPIVSTEVSGRSDHVWNETLEFEVNVCDLPRMARLCFAVYAVMDKMKTKKSTKTMNT
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKTGDLILHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIKFQEYSKLPIYYPPFDKILEKAAEIAKSSDSAMAGRGGKKFYVVLKEIM
ERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWTKLP
PREALELLDFNYPDQYVREYAVGCLKLMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLE
RALANRRIGQMLFWHLRSEVHIPAISVQFGLILEAYCRGSVAHMKVLSKQVEALNKMKTL
NGLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSNLQSPLNPSVILSELHIERCKYMDSK
MKPLWIVYNNKMFGGDFVGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGCL
ATGDHSGLIEAVSNSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTY
DFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQ
YLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K6B2J1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Upupa epops|TrEMBL
MDLGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKLPEIILLE
IAGNCTVEQMKAQIWMRAIEMSQSTDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQNPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKVIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITPD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLETLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRHKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGESEEGAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L4BX41|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nyctiprogne leucopyga|TrEMBL
MELGDCEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAVEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPVALPKHRVTSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFIKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVVEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCTIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKRHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K5ZJ16|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Onychorhynchus coronatus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTADFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTRTNLQSHESSNSDTKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLSKKEVWDHSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEDDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L2N2Q9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhadina sibilatrix|TrEMBL
MELGDNEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPILPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
AQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A096MY63|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Papio anubis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKSNRLARDNELRE
NDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYC
LVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYL
DNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQ
VEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLR
LEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQ
NQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKN
KGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKF
GYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMM
LGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQH
ALN
>A0A7N4NJ79|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sarcophilus harrisii|TrEMBL
MCLSFIMPPAMADNLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISNIKQMLW
KQAHNYPMFNLLMEIESYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKVITRNCDPGE
KLDSKIGVLIGKGLHEFDALEDPEVNEFRSKMRQFSEEKIQSLVGLSWIEWLKHTYPPEQ
EPSIPENLEDKLYGGNLVIAVHFENCQDVFSFQVSPNMSPIKLNELVVRKRLTIHGKEDE
VDPYDYVLQVSGRLEFVFGDHPLIQFQYIRNCVMNRTLPKLTLVECCNIKKMFEQEMIAI
EAAINRNSSNLPLPLPPKKTRLISNVWDNTQPFQVILVKGTKLNTEESVKVHVRAGLFHG
TELLCKPVVSSEISGRNDHVWSEPLEFDINICDLPRMARLCFAVYAVDKVKTKKSTKTIN
PSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDIILHSWSSFPDELEEMLNPMGTVQT
NPYFENATTLHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSGNVSSRGGKKFHAVLKEI
MERDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWPKL
PPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFML
DRALANRRIGQFLFWHLRSEVHIPAFSVQFGVILEAYCRGSVGYMKVLSKQVEALNKLKT
LNSLIKLNAVKLNKAKGREAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDS
KMKPLRIVYNNKVFGGDPLGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGC
LATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEF
TLSCAGYCVASYVLGIGDRHSDNIMVRKTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTMRKDYRS
>A0A7N4NSQ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sarcophilus harrisii|TrEMBL
MPPGVDCPMEFWSKEENQIVEVDFLLPTGVYLNFPVSRNANLSSIKEVLWHNAQSEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVARQGDRVKKLINSQISLL
IGKGLHEFDSLGDPEVNDFRTKMGQFCEEAAAHRQQLGWEAWMHYNFPLQLEPSARGLGA
GALRGPSRTLFVNVKFEGNEESFTFQVSPNDFPLALMACALKKRVTVFRQPALERPEDYT
LKVNGKYEYLYGSYPLYQFQYICRCLHNGQTPHLTMVHCSSILAMRDEQSNFPAQTPKLR
TKPPPIPMKKPSSVSLWALEQPFCIELIQGSKVNADERMKLVVLAGLFHGNEMLCKTVSS
SEVTVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWSSVPDEKGELLNPMGTVWSNPNTESAAALVICIPEVAP
HPVYYPTMEKILELGKNGEHGRFTEDELQQLREILERKVAGELYEHEKDLVWKMRHEIQE
QFPEALARLLLVTKWNKHEDVAQMLFLLSSWPELPVLSALELLDFSFPDRHVGSFAIQSL
RKLTDDELFQYLLQLVQVLARVPPDRVTVPAGRPHRKIGRSSLSSEMHVPSVALRFGLIM
EAYCRGSNHHMKALMKQGEALNKMKALNDFVRVSSQRTTKPQTKELMHVCLRQEIYMEAL
SNLQSPLNPSTLLSEVCVEQCTFMDSKRSRGSQAAGEAAGSCSPGIIFKNGDDLRQDMLT
LQMIQLMDVLWKQEGLDLRMTPYGCLSMGDRTGLIEVVSHSDTIANIQLNKSNMAATAAF
NKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHI
DFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRSYCERAYTILRRH
GLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFNEALRESWKTK
VNWLAHNVSKDNRQ
>A0A3B4TW81|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola dumerili|TrEMBL
MPPGKYGMQEEWAKEGVREIMMDFLLPTGIFLKFPVSPNDTIKNIKKMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERQLLPWQQWMEYSFPCDLEPCCSPCGS
AKSKNTKKIFINVKFEACDESFMLQQDPQDHPGALMRSALKKKATVFRSLRQEPEDYTLQ
VNGSWEFIYGNHPLCQFKYIFSCLRNGQNPHLTMVHHSTVSKYQEDQGRMCSQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFYIHLLQGNRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRP
HPLYYPPLDKISDTEKNGDASISFFSGTKEEYLKLKEIMDNKNYTEFFEDEKELLWKLRT
DVRDHYPESLSKLLLITKWNKREDVVQMVSLLKNWPDLPAIHALELLDYSFPDPTVRSFT
IRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIH
VASVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDFVKSGSQRMTAEDLKICIK
QDSYVEALSDLMSPLNPSIILSEICADKCRFMDSKMKPLWLMYKNHWTQGDMVGIIFKNG
DDLRQDMLTLQMIQLMETLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNN
SNSAATAAFNKDALLNWLKSKNPEEKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMI
RETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCE
RAYKILCRNGMLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNE
ALRESWKTKVNWMMHSLAKDNRP
>A0A3B3D766|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias melastigma|TrEMBL
MPPAMTDLVDIWGAHSPLDGQAPVHVTMDFLLPTGIYIQMEVPREATIQHIKLLLWKQAK
SYPLSSFLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVFRLVTRNCGRAERLLD
SKIGVIIGKGLHELDGINDQEVKDFRSKMQRLSEERMQRVQMMSFSEWLQACFSPQLEPA
AGTAITDGANDWPADLKVIIHFDQSQDSTSLKVLSSCSPFVLIEIALRKWQTTHAPEEET
KKDQYILRVSQCLEFLYGDHPLIQYKYIRSCLQTKESPHLTLVHINTVKAMFDKESSAIG
AVVSRKSSNPPLPLPPKKRTCVWDVSSPFKVVLVKGSTVNADENAKVQVRAGLFHGTELL
CKPAVSNESSGRSNHSLENNTLEFEISVCDLPRMTRLCFAIYAIMEKVKKKSYKNPHINK
YQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDMILHCWSSFPDELEEMLNPIGTVRTNPY
PENATALHIHFPEYSSHPIIFPPFDKVRPPNQPFVSPSGLKWSKHEDMAQLQALLQIWPK
LSPRDALELLDFNYPDQYVREYAVSCLRDMSDEELLQYLLQLVQVLRYEPYYDCALTHFL
LERAQRNRKIGHFLFWHLRSEIHMPAVSIQFALILEAYCRGSIPHIEVLKKQVEALSKLK
SVNELIKLGTIKNTRSKTKEAMLTKEAMITCLKQSGYSEALSDLHSPLNPNVLLSDINVE
KCRYMDSKMKPLWIVYNNKLMSSDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDL
RVVPYGCLATGDRAGLIEVVSSADTIANIQLTSNDASDKRVTKAIEEFTLSCAGYCVATY
VLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKT
GYTEKFGSFRQYCEEAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKS
DEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8D0DNE1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salvator merianae|TrEMBL
MPPGIYCPVEFWSKEANRNIQVDFLLPTGIYLNLLVPCSATLSTIKKYEPLFHMLSDPDS
YVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHE
FDSSGDPEVNDFRAKIHQFCAERAAQRQQLSWRAWMEYSFPVQLEPLAGSPERKNSLRIP
NKNIFVNVKFESGGESFTFHISPKELPMTLMSYAVKKQATVFRHQRINSPEDYTLQVNGK
CEYLYGNYPLYQFQYIHDCLHHGLLPHLTMVHSSSIMALWEEQANGIAHSPKSVARPPPI
PKKKVSHGLFSPIRALLVVQAGLYHGNEMLCKMVSSSEVSVCSEPVWGQRLEFEINVCDL
PRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECSLPMWSS
FPDEKGELLNPMGTVQTNPNTESAAALVIHFPSLSAYPVYYPSLEQAHLSFPVFRTFLLP
VLLCTAQKQQLREILERRSHAELYEHEKDLLWKMRYQIRDHYPGALAKLLVVTKWNKHED
VAQMVHLLQSWRELPVLNALELLDFNFPDRCLQRPDVELLQYLLQLVQVLKYESYLDCDL
TKFLLDRALSNRKIGHFLFWHLRSEMHVPSVAIKFGLILEAYCRGSPYHMKALMKQSEAL
SKMKALNDIVKLSSQKISKLQTKEYMHACMRQETYMEALSNIQSPLNPHIILSKVSVELC
TFMDSKMKPLWIVFSNKNMGGSNMGLIFKNGDDLRQDMLTLQMIHLMDILWKKEGLDLRM
TPYGCLSTGDKMGLIEAVMDSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALDR
AIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERV
PFILTYDFVHVVQQGKTNNSEKFERFRDYCERAYMILRSHGLLFLHLFALMKAAGLPELS
CSKDIQYLKDSLALGKTDEEARKHFQLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C3H5N8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysemys picta bellii|TrEMBL
MELGNYEQPVVMREETKRRRRRMKPYSAASNLSSMELISIEFILPTSNKHTKVQETMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHKFTPDQFILQYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGKIYVVQKQNPAEAVQEFQTQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYSMHPWITSKPLPEYVFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDDPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIVGIDIPVLPRNTELTVFVEANIQHGQQLLSQRRTISKPFTEEVLWNTWVEFDIKI
KDLPKGALLNLQIYCGKAQALSTKVSLQSHDSPNSDSKCKTQLLYYVNILLIDHRSLLRS
GEYVLHMWKISGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEAIVDTDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKREAWDHSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQIIKLLHKVTMDIKSVSAEKYDVTSQVITQLKQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKDRCVIEEKFQAAVERFVYSCSGYCVATFVLGIGDRHNDNIMITES
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTAGKKTSLHFSKFQDICVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTLQKKTKQGVEPGN
>A0A498NR51|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Labeo rohita|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSPELPKH
IYGKLDKANGLRFPLAGNDTGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRK
KTRSMLLSAEQLKMCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLML
MSKDSLYSQLPMDNFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVN
IRDIDKIYVRTGIYHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSIC
SVKGRKGAKEEHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPN
KETPCLELEFDHFSSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTEAD
IEQLRQLGNRDPLSEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLL
KDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDN
PLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVE
AMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLE
DCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQ
GLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKG
EMYDMAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGY
KRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMML
GSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHA
QN
>A0A8C9J410|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Piliocolobus tephrosceles|TrEMBL
MELENYEQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVASDFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESLAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIQGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPAVSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDTCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A4W5RDG3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MEQQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVTMDQIPIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKQLPEYLLFCQEIANFRCLFPEDVCEADYVLRV
CGREEYIYGNQPVRDFHWVRQCLKNGEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAG
THEQLTIDEKDHERIFTISLWDCHRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLL
AQERTSSKAFTEEVLWNTWLEFNIRIRDLPKGARLSLQVSCGKAQTQISKGTYQDNGGSP
VGGGSGNHDGNKTKSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLT
SATNPDKASSMVVAILLDKYCYPVALPKSREGKEAGGEGREAEGGKRGQREMPNHLRKQF
ESIVETDPLHPLSQEDKELLWHFREECMRHPRAYPKLLGSVRWGRQEAVLTTHGLLERSS
VWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDS
ALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQ
VEMTEALQKVTREIKAMSAEKYDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGA
LVVKQCKVMASKKRPLWLQFKRADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIW
EEESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKC
VSEEKFQQAVERFVFSCGGYCVATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSF
LGISKERVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVRAYLALRQHTNLLVILFSMML
MTGMPQLTSKEDIEYIREALTVGRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIK
QGVDKRSA
>A0A8C7RPK0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHEVFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKCPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGESSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNRETPCLELEFDYF
SSPVKFPDMTTVEGHANWTISRELGFSYCQSGQSNRVARDHALTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNIRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCMS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDLAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERCLPVT
>A0A8C2XMM6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MPPAMTDLLDIWAAHSHLAGHALDKITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRAERLLD
SKIGVLISKGLHELDAINDQEVKDFRSKMFRLSEERMQQVQMMTCTEWLQACFSPQLEPP
AGTAITDGLNDRPADLKIIIHFDQSQVRVCSPGGETCIALMELALKKWLTTHGPEEEEAW
RGQYVLRVSHCLEFLCGDQPLIQYKYIRTCMQAKESPRLTLVHTSTVKAMFDKEISTIGA
VVGRKSSNPPLPLPPKRRVPTTCVWDVSSSFKIVLVNGSKVNAEETAKVNVRAGLFHGTE
LLCKPAVSSESSGRSDHTWKDSTLEFDLSVCDLPRMTRLCFAIYAVMDKVKKQKSTKNAH
INKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQT
NPYTENATSLHINFPEYSSHSIVFPPFDKILEKAAEIARASDCVSMGRGGKKFHIELKEI
MERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKL
SPRDALELLDFNYPDQYVREYAVGCLRDMSEEELSQYLLQLVQVLRYEPYYDCALTHFLL
ERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKS
VNELIKLGTIKTARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGINVER
CRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLR
IVPYGCLATGDRSGLIEVVSSADTIANIQLTSNAGSQPIEEFTLSCAGYCVATYVLGIGD
RHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKF
GSFRQYCEEAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEDALK
QFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C9VHS9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MPPAMTDILDIWAADSQLSNEDYVTVDFLLPTGIYIQMEVPREATIQHIKLLLWKQASTY
PLFAFLGEMESHMFECVNQSAVHEALEDETRRLCDVRPFLPVLKLVPRNCGRAERLNSKI
GTLIGKGLHELDALQDQEVKDFRVKMFRISEEKMQRVQMMTWMEWLQSCFSPQLENGVID
GLQEKLFDGALKVIMHFDQSQDTASLMVSPTITPRELTEQAVRKWITTHGPEEDESSCGE
FLLRVSNKLEFLYGEHPLIHYKYVRACVIGKDTPHLTLVHCGMVQAMFEKELSAIGAVVN
RKTSNPPLPLPPKRRGPSQMHTCVWDAQTQFKIVLVKGSKVNAEETAKVQVRAGLFHGTE
LLCKPSVSTESSGRSEHVWNHTLDFDIAVCDLPRMARLCFAIYAVMDKVKKQKSTKNAHI
NKYQTIRKAGKVHYPIAWVNTMVFDYRGHLKTGDNILHCWSSFPDELEEMLNPIGTVRTN
PYTENATALHIYFPEYSSCPVVFPPFDKILEKAAEIARSSDCLPMVGRGGKKFHIELKEI
MERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKL
SPRDALELLDFNYPDQYVREYAVRCLKDMSDDELSQYLLQLVQVLRYEPYYDCALTRFLL
ERAQTNRKIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKA
VNELIKLGTIKNARKTKEAMLTKEAMLTCLRQTGFTETLSDLHSPLNPSVVLSGINVEKC
RYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRI
VPYGCLATGDRSGLIEVVSAAETIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALDR
AIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERV
PFILTHDFIHVIQQGKTGNTEKFGNFRQYCEDAYLILRRNGNLFITLFALMLTAGLPELT
SVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAHNRS
>A0A7J8A044|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myotis myotis|TrEMBL
MPPGVDCPMEFWANEESQSVAVDFLLPTGVYLNFPVSRNANLSAIKKALWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRVKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKQEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKSR
TKPPPIPMKKPSSVSLWALEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVCSNPNTESAAALVICLPEVAP
HPVYYPALDKILELGRHGEHGRATEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RWPEALARLLLVTKWNRHEDVAQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPQTKELMHLCMR
QETYLEALSHLQSPLDPRILLAEVCVEQCTFMDSKMKPLWVMYSNEEAGGDGSVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQY
LKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C2YBK8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coturnix japonica|TrEMBL
SCFNLSRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGAIKQVVWKHA
QYEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLI
NSQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEP
MAKGLGTGLSHTPVKNIFVNVNFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQVSLLSCFDKRVCPPCTHFSGRVVDGSADEMSSARQVTFLP
NYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVW
KQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQ
LKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNAASHPVYYPSFEQV
GNTDVFLRGFLLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLTITKWNK
HEDVAQVRMLELAAGRIFDELWRETSHNLLQVVNKSSAQRSYLDHELFQYLLQLVQVLKY
ESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKV
LMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQETYLEALSHLQSPLNPSIIL
TEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDVLWK
QEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSK
NPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTK
FGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYMILRRHGPLFLHLFALMK
AAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDN
RQ
>A0A5N5KYQ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pangasianodon hypophthalmus|TrEMBL
MHELCGEDNRFSSVMKFRSGLTLPTLRIDTRRVPWFACGVLSAMPPAMTDQLDVWADPVL
DGNDQVAVDFLLPTGIYIQMDVPRESTIQQIKQMLWKQAQVYPLFSLLGEMDGHIFECVN
QAAVHEELEDESRRLCDVRPFLPVLRLITRNCGRAERLLDSKIGVLIGKGLHELDALQDQ
EVKDFRSKMQRISEEKMQSVQMMSWAEWLQSCFSPQIEVGPVDGLCGRNEGWIKITMHYN
QSQDTTSLKVPLSCTVPELMNQALRKWLTTHGLGEDEDCVDDYVLRVSDKLEFLFGEHPL
MYYRYIRSCLLSQEIPHLTLVHCDIVKAMFEREISTIGAVLARKSSNPPLPLPPKRRGPS
QLHTCIWEVQSFFKITLVKGIKVNAEETAKVQVRAGLFHGTELLCKPAVSNESSGRSEHI
WNKTLEFDISICDLPRMARLCFAIYAVMDKVKKQKSTKNMQMNKYQTIRKAGKVHYPIAW
VNMMVFDYRGQLKTGDIILHTWSSFPDELEEMLNPIGTIQTNPYTENATALHIRLPEYSA
HPLTFPPFDKILEKAADIAGSTDSMSMGRGGKKFYIELKEIMERDPLSQLCENEKDLIWT
LRYDCRENFPQSLPKLLLSVKWNKHEDMAQLQALLQIWPKISPRDALELLDFNYPDQYVR
EYAVSCLQDMSDEELLQYLLQLVQVLRYEPYYDCALTQFLLQRAQINRKIGHFLFWHLRS
EIHMPAVSVQFALILEAYCRSSIPHIEVLKKQVEALGKLKAVNELIKLGTIKAKNKTKEA
QLKEAMMKCLRQTGFIEILSDLHSPLNPHILLDDVNVEKCRYMDSKMKPLWIVYNNKLLV
GDTLGIIFKNGDDLRQDMLTLQILRIMDILWKEANLDLRIVPYGCLATGDRTGLIEVVSS
ADTIANIQKNSSNMAAAAAFNKDALLSWLKDKNPGEALEKAIEEFTLSCAGYCVATYVLG
IGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNT
EKFGSFRQYCEDAYLILRKNGNLFITLFALMLTSGLPELTSVKDIQYLKDSLALGKTDEE
ALKQFRQKFDEALRESWTTKVNWMAHNVAHPS
>A0A5C6MQ54|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu flavidus|TrEMBL
MPPGKYGMQEEWEKEGDQRIVMDFLLPTGIFLKFPVSRNDTIGTIKKMVWKNAQSEALYA
ALGDPDSYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVARVGDRVEKLTNTQISQL
TGKGLHEFEAQKNHEVDEFRAKMRTFCEEKAQERQVLPWLQWMECNFPCELEPCSSPVEC
GGVKSKNTKIFINVKFEASDESFMLQQDPQDLPAALMRAALKKKATVFRSVRQEPEDYTL
QVNGRWEYIYGRHPLSQFKYIFSCLRNSQNPHLTMVHHSTIRKYQEEQGRACSQAYKCHR
PSRPPPLPLKKQNTSSLWSINEPFHIRLLHGSRVNAAEGMKLVVQAGLFHGSELLCKMVT
STEVAVCSEPVWDQKLEFDINFSDLPRMSRLCFALYAVIEKNKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIQFPNVR
PHPLYYPPLEKISDLEKNGFAVVATKVEHIKLKEIMDNKNYTEIFEDEKELLWKLRSVVC
DHYPESLSKLLLITKWNKREDVVQMVGLLRYWPDLPAIHALELLDYSFPDPAVRAFTIRC
LRKLSDEELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNSRIGHFLFWHLKSEIHVPS
VSLRFSLILEAYCRGNIWHIKLLIKQNEALLKMKTLSDIVKSGSQKMTVDDLKLCIKQES
YLETLSDLLSPLNPSVVLAEICADKCRFMDSKMKPLWLMYKSPWAQGDMMGIIFKNGDDL
RQDMLTLQMIRLMEILWKKEGLDLRMIPYSCLSTGNKMGLIEVVKNSDTIANIQRNSSNS
AATAAFNKDALLNWLKSKNPEGRLEKAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRET
GQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAY
KILCRNGMLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKVNWMMHSLAKDNRP
>A0A5C6MSJ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu flavidus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKHPISQYKYIRSCIMLGRMPNLMLMAKDSLYSQLPTD
NFVMPSYSRRISTATSYMNGEVAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYISDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSSVKYPDMNAVEDHASWTISREVGLNYTLSGQSNRAARDHILTEGDSEQLRQLTNRDPL
SEITEQEKDFLWRNRYYCMNIPEILPKILLAVKWNSRDEVAKMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECVKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKTEQAMMLFSFLISTHPVEESFKCLPLSDGLFYTLWFPTGGVGLLHETDER
CSSWWMDHQDGLDIPHN
>A0A672ZZG6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
MPPGKYGMQEEWEKEGDQGIMMDFLLPTGIFLKFLVSRNDTIKSIKKMVWKNARSEALFA
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRMFCEEKALDRQRLPWQQWMEYSFPCDLEPCCSPPEC
GNAKSKNTKKLFINVKFEESFMLQQDPQDLPVALIRSALKKKATVFRSVRQEPEDYTLQV
NGRWDFIYGSHPLCQYKYIFFCLRNGQNPHLTMVHHSTISKYQEEQGQMCNQVFKSRSLS
RPPPLPLKKQNTSSLWSINEPFYIQLLQGNRVNADEGMKLVVQAGLFHGSELLCKVVTSS
EVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWV
NTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRQH
PLYYPPLEKISDMEKNGDASFYSKDEYMKLKEIMDNKNYTEFFEDEKELLWKLRSVVRDH
YPESLSKLLLITKWNKREDVVQMVGLLRNWPELPAIHALELLDYSFPDPAVRSFTIRCLR
KLSDGELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVS
CVFGLILEAYCRGNIHHIKLLTNRYLPTLSKSGSQKMTAEDLKLCIRQESYVEALSDLLA
DKCRFMDSKMKPLWMMYRNPFVQGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLD
LRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDEKLEKAIEEFTLSC
AGYCVATYILGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFV
HVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLK
DSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A7N6AA72|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPGKYGMQGEWEKEGDHEIMMDFLLPTGIFLKFPVSRNDTIKTIKRMVWKNARSEALFT
ALGDPDAYVFTCINHTAEREELEEESRRISDVQPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEVQKNHEVNEFRTKMRVFCEEKQGCSGKSDQVLCYDEATVEQHKHFMLQQDP
QDPPLVLMRSALKKKATVFRSVRQEPEDYTLQVNGRWEFIYGNHPLCQFKYIFSCLRNGQ
NPHLIMVHHSTISKYQEEQGRMCNQVYKSCSLSRPPPLPLKKVRGQRTSACVFPLQLVVQ
AGLFHGSELLCKVVTSSEVTVCSEPLWDQKLEFDINVADLPRMGRLCFALYAVIEKAKKP
RGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLTLTQIDLLNPMGTVERNPNVDSAAG
LLIRFANIRPYPLYYPPLDKVLVLKTLYQSLKCLFVLLCQKQTKSFVKLKEIMDNKNYTE
FFEDEKELLWKLRAEVRSSYPESLSKLLLITKWNKREDVVQMVSLLRNWPDLPAIHALEL
LDYSFPDPAVRSFTIRCLRNLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRR
IGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIRLLTKQNEALAKMKSLSDFVKSG
SQKMTVEDLKLCIRQESYLEALSDLLSPLNPSIILSGIWLVADKCRFMDSKMKPLWLMYK
NPGTQGDMVGIIFKNGDDLRQDMLTIQMIQLMENLWKKEGLDLRMIPYGCLSTGNKTGLI
EVVKNSDTIANIQRNCSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEVFTLSCAGYCVA
TYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQG
RTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLCLG
KSDDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A7N6AT26|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MAAVPLHSHTLKPVVLREEIRRRRRKKAITSSSSISMDQITVEFVLPTATWGSNPDSLQL
EVAGNWTVEQVKAQVWLKAVTSNLCPEFYQRFSPDHCILLYQKKGNLCEIYDKHQVFQTL
DCIRYWRALKKDVGKIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRRIELCDRDPKLYSMDPWVTRKPLPEHLLSKVSNGHILVVIHMSTASHTIKVSIDD
TPAQVLASFFNKTANKRVLLGIPDNVCETDYVLRVCGRYEYLYGDKPLQNFNWIRQCLKN
GEEIHLVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNR
KFRVKVLGIDIPTLPKVPEFVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIK
IKDLPKGARLSLQVVCGKQPQTPNSKGRKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWK
MPEKSEESSSSINADKLTSATNPDKESSMAIAILLDKYCYPVVLPKSRDVGRDVGAVGEE
SEGGERGQREMPNHLKKQFEAIVTTDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSV
KWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDV
LRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVL
LEAYLRGCGEAMLQDFRKQVEMTEALQKVTREIKTMSADKYDVTAQVVFQLRQKLEILQS
SGLPDNFRVPYDPGLRAGALMIEQCKVMASKKKPLWLQFKKADPTTLSKDPIGIIFKDGD
DLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGWLSS
>A0A6J2C8B7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zalophus californianus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECFKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVDCLRQMRSEVHIPAVSVQFGVILEAYCRGSVGHMKV
LSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVIL
SELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWK
EAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEY
NSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSK
FGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALML
TAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDY
RS
>A0A7K7C1G2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aphelocoma coerulescens|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYRAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTVDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAVSIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQDIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMDIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCIIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C3KF46|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calidris pygmaea|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMTKGLGA
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGDQPRQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQ
ALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAINSLKKLT
DNELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRF
GLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHVCMKQETY
LEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLR
QDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMV
ATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETG
QLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYM
ILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRE
SWKTKVNWLAHNVSKDNRQ
>F7DD93|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Equus caballus|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSGAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEDTVAFQQQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDQVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKVRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASADTPSSESKGKVQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCSFPDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALVRFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGMAMLHDFTQQVQVIEVLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKRADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKERCPLEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8C6FGY5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Moschus moschiferus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A672RPC0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDATGSHSRALYVYPPNVESSSELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEVMI
CFFKINIFVHLTFFFVKFNSRLARDHAMTEADIEQLRQLGNRDPLSEITEQEKDFLWRHR
QYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFA
VRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEM
HNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFL
VEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQ
NNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSH
TIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAIDLFTRSCAGYCVATFILGIGD
RHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKT
REFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQE
ALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A7L2T6A2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pomatostomus ruficeps|TrEMBL
MPPGIYCPTEFWSKGENQSIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQHEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGRGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGA
GSLQVPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQRPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLHALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKAPKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A672R7H2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPGVYGMQDVWEREGWQQVNMEFLLPTGIYLNFTVTSSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWDQWMEYNFPCDLEPCSVVAQS
GKSCSDKKIFVNVKFEGSEETFVLQQGPQDLPMFLKQNALRKKSTVFRSAKQEKPEDYAL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDISASDLPRMSRLCIALYGVIEKTKKRPTKKKNKSSDCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGLNGEKTVATKEEHLKLREIVDNKNYTEFFEDEKELLWKLREVVRQ
RYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHARSFTIRCL
RKLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVSSV
SLRFGLILEAFCRGSIFHLKNLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIK
QDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDTLGIIFKNGDDL
RQDMLTLQMIQLMDVLWKTEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECC
EQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLMDSLALGKSEEEALKNFKVKFN
EALRESWKTKVNWMMHTFAKDNR
>A0A3Q3LZU3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSRNDTIKLVWKNARSEALFTALGD
PDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFEAQKNHEVNEFRTRMRQFCEEKSQERQMLPWQQWMEYSFPCDLEPCCSLPSTKSRN
TKKIFINIKFEACDESFMLQQDPQDLPVALMKSALKKKATVFRSVRLEPEDYTLQVNGSW
DFIYGKHPLRQFKYIFSCLRNGQNPHLIMVHRSTISKHQEEQERMCNQVYKSRSQSRPPP
LPLKKNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSSEVTVC
SEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVNTMVF
DYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYP
PLEKISDMERNDDTVTATKEEHQKLKEIMDNKNYTEFFEDEKELLWKLRYEVCSLYPESL
SKLLLITKWNKREDVVQMVGLLRNWPDLPAIHALELLDYSFPDPAVRFFTIRCLKKLSDN
ELLQYLIQLVQVLKYESYLDCDLTTFLLERALANRRIGHFLFWYLRLDTFAFWADPGSLL
LKLLDDLKLCIRQESYLEALSDLLSPLNPSIILAEICAHKCRFMDSKMKPLWLMYGNPWA
QGEMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMSPYGCLSTGNKMGLIEAVK
NSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVL
GIGDRHNDNIMIRENGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNN
SEKFERFREYCERAYKILCRNGMLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSED
EALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A2R8Y2F6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFESSQGECFQLFPIQYDIGRGFVT
>O00334|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MPPGVDCPMEFWTKEENQRVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSAPKAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSAQTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNP
TGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKLPGGMLLASREWRPELLWMRLHAED
SAPSRMIGVAMPGLGVLPGLVQAPGDAECSRLLQILELGRHSECVHVTEEEQLQLREILE
RRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAPDALPAVSWPELPV
LSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLER
ALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSGGTVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DLVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFREKFNEALREGWKTKVNWLAHNVSKDNRQ
>A0A8J4KGD6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eudyptes chrysocome|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEERGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K6MLE4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panurus biarmicus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEVMLLE
IAGNCTVEQMKAQIWMRAIEMSQTADFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMQPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQPHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPGSFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILSQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A0S7K282|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poeciliopsis prolifica|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLINIKQQLFIEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIMSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLENFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCENVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVSLFDYMDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
RFSQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSATDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCLNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDRVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNHGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8C0AC14|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus grunniens|TrEMBL
MGTANPQPGWLCCRIAVLWMVLAGSGKDDWYLRSEKAGCPPGLTAPWNSGPRRRIRAWQL
ISCSPRGLSELPVSRNANLSTIKKVLWHRAQYEPLFHMLSDPEAYVFTCVNQTAEQQELE
DEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHEFDSLQDPEVNDFRGKM
RQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGPGTLRVPNRVLLVNVKFEGSEESF
TFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYTLQVNGKHEYLYGSYPLCQFQYIC
SCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRTKPPPIPMKKPSSVSLWSLEQPF
YIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSVCSEPVWKQRLEFDINICD
LPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGEHCLYMWP
SVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAPHPVYYPSLDKILELGRLGEHGRF
TEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQEHFPEALARLLLVTKWNKHEDVAQ
MLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYES
YLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLM
KQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDPSTLLAE
VCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKNGDDLRQDMLTLQMIQLMDILWKQ
EGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKN
PGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKF
GINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRA
AGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNR
Q
>A0A6G1AQN7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crocuta crocuta|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8I3Q525|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYCFPLQLEPSARSWGP
GTLRVPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMR
QEAYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C5ZSS7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Marmota marmota marmota|TrEMBL
MELENYEQPVILREDNLRRRRRMKPRSVAASLSSMELIPIEFVLPTSQRDTKIPETALLH
VAGHGNVEQMKAQVWLRSMETSVAADFYHRLGPDHFILLYQKKGQWYEIYDKYQVVQTLD
CLRYWKMLNKSPGQIHVVQRHAPSEETLAFQQQLTALIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVASRDARLYAMHPWVTSKPLPEYLSRKIINNCIFIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWIRHCLKNG
EEIHLVLDRPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIFCGKAPALSGKASAETPSSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLQDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLETLQNSNLP
KSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A3B3SA05|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Paramormyrops kingsleyae|TrEMBL
MESHMFECVNQSAVHEELEDETQRLCDVRPFLPVLRLVPRNCGRAERLDSKIGVLIGKGL
HELDALQDQEVKDFRSKMFRISEEKMQRVQMMTWMEWLESCFSPQVEVGAIDGLQEKLFE
GALKVTMHFSQSQDTASLKVSPAITPRELREQALRKWLTTHSSSEEVQEEVRWDDYVLRI
SGKLEFLTGEHSLIHFKYIRTCVMATESPHLTVVHCSAIQSMFEKEITAIGAVVNRKTSN
PPVPLPPKRRGPSMHTCVWDIHTPFRITLVKGAKVNAEETTKVQVRAGLFHGTELLCKPA
VSSETSGRSEHTWGQSLDFDINVGDLPRMARLCFAIYAVMDKVKKQKSTKSPHINKYQTI
RKAGKVHYPIAWVNTMVFDYRGHLKTGEVVLHCWSSFPDELEEMLNPIGTIQTNPYTENA
TALHVQFPEYHAYPIVFPAFDKILEKAAEIARGSDCMPMVGRGGKKFHSELKEIMERDPL
SQLYENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDAL
ELLDFNYPDQYVREYAVRCLCDMSDDELSQYLLQLVQVLRYEPYYDCALSRFLLERAQAN
RSIGHFLFWHLRSEMHMPAVSVQFALILEAYCRGSIPHIEILKKQVEALNKLKAVNELIK
LGTIKNVRKAKEAMLSKEAMLTCLRQTGYAETLSDLQSPLNPQVLLSGISVEKCRYMDSK
MKPLWIVYNNKLLDGDTLGIIYKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCL
ATGDRSGLIEVVSAAETIANIQLTNSNVAAAAAFNKDALLNWLKEKNSGDALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTH
DFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQ
YLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAHTWS
>A0A8C4DE60|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHDLFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMTIIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNEQLRQVCNRDPL
SEITEQEKDFVWRHRQACVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRYINKVHLDIMYIMML
PYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAI
DLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPF
VLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQ
SFDDIAYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8C4DJZ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MTPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMLKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEGYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERSHLHLTYCYRLLQAVKHCYTLLQAVKHCYTLL
>A0A8C4F0H6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MDGKQIQVSDEEPRVLREENRRRRRKKAITSSSSSSMDQIAVEFVLPTTARGGNSPDTLQ
LEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRLSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQMVPRPQPSDESLQYQRYLNNLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVGNGNILVVIHIGTAIRLSVLLLF
HFLTIICLTANKRALLGIPENMCEEDFVMRVCGREEYLYGDKPLQNFNWIRQCLKNGEEI
HLVLESPPDPELDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRV
KVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKSFNEEVLWNCWLEFNIKIKDL
PKGARLNLQVVCGKQPQTKAHVCLSVHLSGKTKSRLLYYVNLLLIDHRSLLRQGEFILHM
WKMPEKSEESSSSINADKLTSATNPDKASTMAIAILLDKYCYPVVLPKSRDVGRDIGAGG
EEAEGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLG
SVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLGDD
DVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYA
VLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTRDIKAMSADKYDVTAQVVFQLRQKLEAL
QLSGLPKSFRVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKD
GDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQS
VVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMI
TESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCV
KAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEI
CREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A667YXL0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDTNGPHSRALYVYPPNVESSAELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDWVPEQVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKPLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLSYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKFPDMTTIEEHANWNISRELGFNYCHSGLSNRLARDNPLTDSDSEQLRLVCNRDPL
SEITEQEKDFLWRHRHQCVSMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A674BXX5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPGEYGMLGEWKKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRPFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPMILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTIVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKLVVQAGLFHGSELLCKVVTSGEVNVCSEPLWDQKLVFDISVSDLPRM
SRLCFALYAVIEKAKKPRSTKKKNKKADCPLAWVNTMVFDYKDQLKTGEFLLSTWPSVPD
DKGDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPHFDKVHLILHTRFNSRHCTFH
MKLKEIVDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKLLLITKWNKHEDVAQMVAFL
QKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQLVQVLKYESYLDCD
LATFLLERALSNKRIGHFLFWHLKSEMHVSSVSLRFGLILEAYCRGNIYHIKSLWKQNEA
LNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLLSPLNPSIKLSEICADR
CKFMDSKMKPLWLMYKNKWVQGDAVGIIFKNGDDLRQDMLTLQMIQLMEILWKKEGLDLR
MIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEDKLD
QAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNFKSKFGINRER
VPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFAMMKAAGLPEL
SSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDSRL
>A0A3Q3DP23|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hippocampus comes|TrEMBL
MPPRPSSGELWGMHLMPPSIKVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDCNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETSTKSLWTINGALRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVSGSNPNKETPCLELEFDHF
SSPVKFPDMTIIEDHANWNISRELGFNYCPTGLSNRVARDNSFTDIDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHYCVNMPDILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLGRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDGKFLTSSTFALELKMQSLMLPYGCLSIGDCVGLIE
VVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAVDLFTRSCAGYCVATF
ILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQ
ECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALD
KTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A3Q3E2A0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hippocampus comes|TrEMBL
MPPGKYGMQEEWEREGERGIKMDFLLPTGIYLTFPVSHKDTIKSIKTMVWENAREEALFM
ALGHPDAYVFTCIKQTGEREELEEESRRISDVQPFMGVLRLVAREGDRVEKLNNSQISFL
IGKGLHEFDAQKNHEVSEFRTKIRAFCEEKAQLRQASPWQQWMAYMYPCDLEPCCSLPMC
GKQKLQMRAFTGKVKPEDYTLQVNGRWEFIYGRHPLCQFKYIFSCLRTGQNPHLTMVHHS
TISKYQEEHGRMCSQVCKSRSLSRPPPLPVKKLVVQAGLFHGSELLCKVVTSSEVAVCSE
PLWDQKMEFEINVADLPRMSRLCFALYAVFDKAKKPRGTKKKNKKVDCPIAWGNTMVFDY
KDQLKTDEVLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPYPLYYPPL
DKVRMIKNAGHSTSSNIKLKEIMDNKNYTECFEDEKELLWKLRTEVRDHYPENLSKLLLI
TKWNKREDVIQMVSLLRNWPELPAIPALELLDYSFPDPAVRSFTIRCLRKLSDDELLQYL
IQLVQVLKYESYLDCDLTTFLLERALFNRRIGHFLFWHLRSEIHVPSVSLRFGLILEAYC
RGNIHHIKLLTKQNEAQGKMKVLSDFIKSGSQKVNAEDLKLFIRQESDAFSNLLSPLNPS
VILAEICVDKCRFMDSKMKPLWLMYKNPWTQGDMMGIIFKNGDDLRQDMLTLQMIQLMEN
LWKKEGLDLRMIPYGCLSTGNKMGFIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWL
KSKNPEDKLEQAIEEFTLSCAGSCVATYILGIGDRHNDNIMIRENGQLFHIDFGHFLGNF
KRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFA
MMKAAGLPELSSFKDIQYLKDSLALGKTEEEALKSFKVKFNEALRESWKTKVNWMMHSLA
KDNRP
>A0A667X834|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MPPAMTDLLDMWAAHSPLAGHATDVITMDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TYPLFPALGEMEGHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQKMTWTEWLQACFSPQLENG
GGAITDGPALLSPCISVWSFPLLQDTASLKVSPSCTPTELMELALRKWLTTHGPEDEARR
GQYVLRVSQRLEFLCGDHGLIQYKYIRSCTQAKESPHLTLVHTSTVKAMFEKEISAIGAV
VTRRSSNPPLPLPPKRRIPTVSFEICVHFKIVLVKGSKVNAEESVQVRAGLFHGTELLCK
TAVSSESSGRSEHTWSDGTLEFDICVCDLPRMTRLCFAVYAVMDKVKKQKSTKNTHLNKY
QTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHSWSSFPVVFAATCRLNHLLIILLSL
PKLFSSQILYPFLFSILLLTNEPLSFSSPLVSQGRGGKKFHIELKEIMERDPLSQLCENE
KDLIWTLRHDCHENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNY
PDQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLDRAQSNRKIGHFL
FWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNA
RSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMDSKMKPLWI
VYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDMLWKEASLDLRIVPYGCLATGDRA
GLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALERAIEEFTLSCAGY
CVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVI
QQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSL
ALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A673ZG00|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MEYYSLLSLSSVKSIRLCLWVLVPAMPPAMPDDLDLWAAHSQLSGEDLVTVDFLLPTGIY
IQMDVPREATIQHIKLLLWKQAQSYPLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCD
VRPFCPMLKLVTRNCGRAERLLDSKIGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKM
QRVQLMTWSEWLQACFSPQLEPGGGATPLTDGVNDKQAEASLKVTMHFDQSQDTASLKVW
PSTSPSELMEQALRKWLTTHGPEEEGRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQ
AKECPHLTLVQVSSVQAMFEKEISAIGAVVNRKSSNPPLPLPPKRRGPSQVNTCVWEVST
QFKIVLIKGSKVNAEESAKVQVRAGLFHGTELLCKPVVSSESSGRSEHVWNRTLEFDITV
SDLPRMARLCFAVYAVMDKVKKQKSTKNAHINKYQTIRKAGKVHYPVAWVNTMVFDYKGQ
LKTGDIILHSWSSFPDELEEMLNPIGTIQTNPYTENSTALHIHLPDYNPHPILFPPFDKI
LEKAAEIAGSSDCSTMVLSRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCMENF
PQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLRD
MSDEELSQYLLQLVQVLRYEPYYDCALTRFLLNRAQCNRNIGHFLFWHLRSEMHMPAVSV
QFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMM
TCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMDSKMKPLWIVYNNKLLGGDTLGII
FKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSSADTIANI
QLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFR
NYCEQAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKVIGRFTWDSLALGKTDDE
ALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A7K5WEW4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hylia prasina|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQA
HSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPAEKLD
SKIGVLIGKGLHEFDALQDPEVSDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLMECSTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K9C8E8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Psilopogon haemacephalus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTNNKHTKAPEIILLE
IAGNCTVEQMKTQIWMSAIEVSQATDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVIQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILQSFFTKMAKKKSLMDIPEDHSEMDFVLRICGRDEYITGETPIKDFQWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVVWNIWLEFDIKI
KDLPKGALLNLQMYCGKAQGLSTRTNLQSRESPNSDSKCKTQLLYYVNILLIDHRFLLRT
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPVALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIITTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDLSTLDVGLTMQLLDCNFSDESVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRALRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQTS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKEKCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKRHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8B9DZZ6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anser cygnoid|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GLLHTPTKNIFVNVKFQSGGESFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANTPKMS
PKPPPLPKKKPNYSSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPNVAS
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A663LS71|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Athene cunicularia|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCISSPPRMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRQKLQLREILERRSHTELYEHEKDLVWKMRYDIRDQYPQ
ALAKLLIITKWNKAPLWIHLSMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKK
LTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVAL
RFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHVCMKQE
TYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDD
LRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSN
MAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRE
TGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKA
YMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEAL
RESWKTKVNWLAHNVSKDNRQ
>A0A7K6GR19|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Malurus elegans|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGPGS
LHIPTKNIFVNVRFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQRPEDYTLQ
VNGKCEFLYGNYPLYQFQHIRRCLQRGRTPHLTMVHSSAIIAMRDEQTNCIASPPKAASK
PPPLPKKKPNYGSLWSLEQPFYIELLQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSE
VNVCSEPVWKQRLDFDINICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAWVN
VMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKQQLKEILERRSHTELYEHEKDLVWKMRYDIR
EQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKLSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A852DCY2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Passerina amoena|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQRQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>L5KGU6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pteropus alecto|TrEMBL
MEFWTKEENQNVTVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQFEPLFHMLSDPEAY
VFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHEF
DSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGPGTLRVPNR
ALLVNVKFEGSEESFTFQVSSKDVPLSLMACALRKKATVFRQSLVEHAEDYALQVNGRHE
YLYGSYPLCQFQYICSCLHSGLTPHLTMVHCSSILAMRDEQSDPAPQVQKPRTKPPPIPM
KKPSSVSLWSLEQPFCIQLIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVNVCSE
PVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLTLFDY
KDQLKTGECCLYMWPSVPGLGDSAEQGLFLQILELGRHGEHGRFTEEEQLQLREILERRA
SGELYEHEKDLVWKMRHEVQERFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSA
LELLDSSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCAPNSXXXXXXAR
SATSSSGTSGEAQPLPPPSSSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKL
KALNDFVKVSSQKSPKPQTKELLHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFM
DSKMKPLWVMYSNEEAGSEGSVGIIFKNGDETHAFPSGAGGTDLRQDMLTLQMIQLMDVL
WKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLK
SKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQGPPPRRFRGYCERA
YTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEAL
RESWKTKVNWLAHNVSKDNRQ
>U3KM40|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryctolagus cuniculus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7J7X7Q0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinolophus ferrumequinum|TrEMBL
MPPGVDCPMEFWTKEENQTVAVDFLLPTGVYLNFSVSRNANLSTIKKVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLSWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSMSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALIICLPEVAP
YPVYYPALDKILELGRHGEHCRFTEEELQLREILERRGSGELYEHEKDLVWKMRHEVQEH
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSLR
KLTDDEVFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSIHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPHTKELMHLCMRQ
ETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYNNEEAGSDGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q2TG62|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fundulus heteroclitus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLSH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGSHSRALYVYPPNVESSPELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDFVPEQVIAEAIRKKTRSMLLTQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMSKDSLYSQLPTD
NFTMPSYARRISTATPYMNGETATKCLWTISGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMFVIEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMSKIEDHANWIISRELGLNYCHSGLGNRLARDNPLTESDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHYCINMPDILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLGRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGVYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSEMLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHALHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A6P4VXW4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera pardus|TrEMBL
MPPFHCLARPIRVDIHKVPAIALQVAQGMELDNYEQPVVLREDNRRRRRRMKPRSTTASL
SSMELIPIEFVLPTSQRNSKTPETALLHVAGHGNVEQMKAQVWLRALETSVATDFYRRLG
PDHFLLLYQKKGQWYEIYDKYQVVQTLDCLRYWQVLHRSPGQIHVVQRHAPSDETLAFQR
QLTALIGYDVTDVSNVHDNELEFTRRRLVTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLL
KKITNNCIFIVIHRSTTSQTIKVSADDTPGAILQSFFTKMAKKKSLMDIPESQSEQDFVL
RVCGRDEYLVGETPIKNFQWVRQCLKNGEEIHLVLDTPPDPALDEVRKEEWPLVDDCTGV
TGYHEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNADLTVFVEANIQHGQQ
VLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPRGALLNLQIYCSKAPVLAGKTSAETPSS
ESKGKTQLLYYVNLLLIDHRFLLRHGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKEN
SMSISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDK
ELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLD
CNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIG
HFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTDQVQVIEMLQKVTLDIKSL
SAEKYDVSSQVISQLKQKLENLQNSNLPKSFRVPYDPGLKAGALVIEKCKVMASKKKPLW
LEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCIST
GDKIENQTRERAAWLKSPLPSCQQRPSHSSSGSGPKPQCLSAFVHLLIGMIEIVKEATTI
AKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRH
NDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQK
FQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYF
LDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A665UAK8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MSPGKYGMQEDWEKDGVQEIMMDFLLPTGILLNFPVSRNDTIKNIKRMVWKNARSEALFN
ALGDSDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNHEVNEFRSKMRTFCEEKAQERQQLSWQQWMEYSFPCDLEPCCFPCGS
AKSKNTKKIFINIKFEACDESFMLQQDPQDLPEALIRNALKKKATVFRSVRQEPGDYTLR
CNGTWEFIYGNHPLCQFKVSSHKTPSLVKCPTFTDQYDQQHMYNKNPPQPTNQNTSSLWS
INEPFYIHLVQGNRVNADEGMKLVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQRLEFD
INVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFL
LSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIHFPNIRQYPLYYPPLDKVYLRPREE
RYLIWLRADVREYYPESLSKLLLITKWNKREDVVQMVSLLRNWPDLPVIQALELLDYSFP
DPAVRSFTVRCLRKLSDDEILQYLIQLVQVLKYESYLDCDLTTFLLERFAFWFDSGGLLQ
GEHPPHQALTVYLSSALQNEALGKMKALSDFVKSGSQKMTAEDLKLCIRQESYLEALSDL
LSPLNPSIILEEICADKCRFMDSKMRPIWLMYKNQWAQGDMMGIIFKNGDDLRQDMLTLQ
MIQLMETLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNNSNSAATAAFNK
DALLNWLKSKNPEEKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDF
GHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTSNSEKFERFREYCERAYKILCRNGT
LFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVN
WMMHSLAKDNRP
>A0A665UA85|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MSPGKYGMQEDWEKDGVQEIMMDFLLPTGILLNFPVSRNDTIKNIKRMVWKNARSEALFN
ALGDSDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNHEVNEFRSKMRTFCEEKAQERQQLSWQQWMEYSFPCDLEPSPLEIPL
PRQKHHLQNISQEEEALIRNALKKKATVFRSVRQEPGDYTLRCNGTWEFIYGNHPLCQFK
VSSHKTPSLVKFNENVLQEMTENFIFISCGSFLQQNTSSLWSINEPFYIHLVQGNRVNAD
EGMKLVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQRLEFDINVADLPRMSRLCFALYA
VIEKTKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPM
GTVEKNPNVDSAAGLLIHFPNIRQYPLYYPPLDKICDLEKNEIMDNKNYTEFFEDEKELL
WKLRADVREYYPESLSKLLLITKWNKREDVVQMVSLLRNWPDLPVIQALELLDYSFPDPA
VRSFTVRCLRKLSDDEILQYLIQLVQVLKYESYLDCDLTTFLLERVGDSCGLCEFAFWFD
SGGLLQGEHPPHQALTVYLSSALQNEALGKMKALSDFVKSGSQKMTAEDLKLCIRQESYL
EALSDLLSPLNPSIILEEICADKCRFMDSKMRPIWLMYKNQWAQGDMMGIIFKNGDDLRQ
DMLTLQMIQLMETLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNNSNSAA
TAAFNKDALLNWLKSKNPEEKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQ
LFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTSNSEKFERFREYCERAYKI
LCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRES
WKTKVNWMMHSLAKDNRP
>A0A3Q7WS31|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus arctos horribilis|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRQEYLYGGYPLCQFQYICGCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLGSWPELPVLSALELLDCSFPDRHVGSFAIKSL
RKLTDDELFRYLLQLVQVLKYESYLDCELAKFLLARALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHVCMR
QETYLEALSNVQSPLDPSTLLAEVCVEQCTFMDSKMKPLWLVYSSEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A1A7YM44|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Iconisemion striatum|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFKAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTQEQLK
MCVQEYQGKYILKVCGCDEYLMEKYPLSQYKYVRSCIMLGRMPNLMLMTKDSLYSQLPTN
NFTMPSYARRISTATPYMNGETATKCLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPEIPRAARLCLSICSVKGR
>A0A1A7WL24|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Iconisemion striatum|TrEMBL
REEIRRRRRKKAFTSSSSTSMDQITVDFVLPSAARGGSSSDSLLQLEVAGNWTVEQVKAQ
LWMKAVALNFCPDFFQRLSPDHCILLYQKKGNICEIYDKHQVFQTLDCIRYWRALKKEAG
RIQLVHRPQPTDESLQYQRYLNHLIGYDVTDVSNVHDDELEFTRRKLLTPRRIELSDRDP
KLYSMDPWVTRKQLPEHLLTKVNNGYILVVIHVSTSSQTIKVSIDDTPSQVLSSFFAKTQ
NKRVLLGIPDNMCESDFVLRVCGREEYLYGEKPLQDFNWIRQCLKGGEEIHLVLVTPPDP
ELDLVQKEDWAQVDDCTGVTGTHEQLTITEKDHERVFTISMWDCNRKFRMKVLGIDIPTL
PKVPDFAVFVEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKIKDLPKGTRLNLQV
ICGKQPQMPNSRGGSYYETTSGTCCLEGKTKNRVLYYVNLLLIDHRSLLRQGEFILHMWK
MPEKSEESSSSINADKLTSATNPDKASSMAVAISLDKYCYP
>H0YXY2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCASSSFSSMELISIEFILPTSNKHTKAPETMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQELQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKIINNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
DEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSSLDVGLTMQLLDCNFSDENVRAMAVQKLESLDDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCIIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C2ATU3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNDLGMNGEKTTKEEMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIR
CLRKLSDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVP
SVSLRFGLILEAYCRGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVC
IKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGD
DLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNS
NSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIS
ETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQ
AYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKVRTAQTGII
>A0A7L1LBS0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Himantopus himantopus|TrEMBL
MELGDDEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVRAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C2HE28|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVI
SNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKTLILTDGTVFFQHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQRYPES
LPKLLLITKWNKHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLSD
DELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSLRFG
LILEAYCRGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYM
EALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQDML
TLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAA
FNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMISETGQLFH
IDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERSVHSKLVLFCSLLP
FLAHKKKRLSFYDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A8C1QUA2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
LVLSAMPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKE
AQTYPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERI
LDSKIGVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLE
TESVENLIDKHEGVIKITMHYDQSQVCSVILALKKWQTTHGPEEDIGTRSDYVLRVSCRL
EFLLEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAIFEKEICTIGSVLARKASNPPLP
LPPKKRTPTVRTLSVFPALQLIKGALSFVPLAVRAGLFHGTELLCKTAVSSESSSRSEHV
WNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHYPIAW
VNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYST
QPVVFPAFDKILEKAAEIAGASDSMTIGRGGKKFYIELKEIMERDPLSQLCENEKDLIWT
LRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVR
EFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRS
EMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKLGTIKTKTKQAHL
KEAMMTCLRQTGFIETLSNLHSPLNPNILLAGVHVERCKYMDSKMKPLWIVYHNKLLGGD
TVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSAD
TIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIG
DRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEK
FGNFFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEA
LKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A8C2DI12|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVAQS
GKSLLIFPSCAETFVLQQDPQDLPMLLKRNALRKKSTVFRAAKQEKPEDYTLQVNGRWEF
IYGEYPLCQFKVSLKVTTSSRLHSYSTTLSDSRTHVFLNLILLFCYFFYQNTSSLWSIHE
PFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSNEVSVCSEPVWDQKLVFDIGV
SDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFSLSTW
PSVPDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKVHCLLFRYYKRRGKKS
NVLIVDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVGLLRK
WPELPAIHALELLDYSFPDPHVRSFTIRCLRNLRDDELFQYLLQLVQVLKYESYLDCDLT
CFLLKRALANKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSIFHIKSLMKQNEALN
KMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCTDKCK
FMDSKMKPLWLMYKNKYDHVGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYG
CLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFIL
TYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKD
IQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A8D0FJP3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strix occidentalis caurina|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>S7NNI4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myotis brandtii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWGINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLEMEFDWF
SSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDP
LSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAM
ELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDIL
KQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A1A8URB1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius furzeri|TrEMBL
MPPGKYGMQEEWEKEGDQNILMDFLLPTGIFLKFPVPRNDTIKNIKKMVWRNAKTEALYC
GLGDPEGYVFTCINDTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNSHISSL
IGKGLHEFEAQKNHEVDEFRSKMRTFCEEKALERHNLPWQQWMEYSFPCDLEPCCSPPVH
GGTKSKHTKKLFINVKFEACDESFMLQQDPLDIPVALMKSALKKRATVFRSVWQEPEDYT
LQVSGRWEFIYGNHPLRQFKYIFSCLRNGQNPQLIMVHHSTISKYQEEQGQLCSQVGKIR
SQSRPPPLPMKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQKLDFDINVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKRADCPI
AWVNTMVFDYKDQLKTGEFILSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPPLDKMIVMERNGDAVFATKVERMRLKEIMDNKNSTEFFEDEKELLWKLRTEV
RDCYPESLSKLLLITKWSKREDVVQMVSLLRNWPDLPAIQALELLDYSFPDPAVRSFTIR
CLRKLSDNELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVA
SVSLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDIVKSGCQKMTVEDLKLCIRQE
SYMEALSNLMSPLNPSIILVELCADKCRFMDSKMKPLWMMYKNPSEHADMVGIIFKNGDD
LRQDMLTLQMIHLMEDLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKHSDTIANIQRNNSN
SAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEWA
YKILCKNGTLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEDEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A8C6PMH4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius furzeri|TrEMBL
MPPGKYGMQEEWEKEGDQNILMDFLLPTGIFLKFPVPRNDTIKNIKKMVWRNAKTEALYC
GLGDPEGYVFTCINDTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNSHISSL
IGKGLHEFEAQKNHEVDEFRSKMRTFCEEKALERHNLPWQQWMEYSFPCDLEPCCSPPVH
GGTKSKHTKNFMLQQDPLDIPVALMKSALKKRATVFRSVRQEPEDYTLQVSGRWEFIYGN
HPLRQFKVSRIMNANVMGRKKDQNKNKIPISSSFCSFLQQNTSSLWSINEPFYIHLLQGS
RVNADEGMKVGVAGLFHGSELLCKVVTSSEVTVCSEPLWDQKLDFDINVSDLPRMSRLCF
ALYAVIEKTKKPRGTKKKNKRLPSRFQDCPIAWVNTMVFDYKDQLKTGEFILSTWPSVPD
DKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPLDKMIVMERNGDRMRLKEIM
DNKNSTEFFEDEKELLWKLRTEVRDCYPESLSKLLLITKWSKREDVVQMVSLLRNWPDLP
AIQALELLDYSFPDPAVRSFTIRCLRKLSDNELLQYLIQLVQVLKYESYLDCDLTTFLLE
RALSNRRIGHFLFWHLSFTSQNEALGKMKLCIRQESYMEALSNLMSPLNPSIILVELCAD
KCRFMDSKMKPLWMMYKNPSEHADMVGIIFKNGDDLRQDMLTLQMIHLMEDLWKKEGLDL
RMIPYGCLSTGNKMGLIEVVKHSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKL
DQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRE
RVPFILTYDFVHVIQQGRTNNSEKFERFREYCEWAYKILCKNGTLFVNLFAMMKAAGLPE
LTSSKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A7J7T1B1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pipistrellus kuhlii|TrEMBL
MPPGVDCPMEFWANEENQSVAVDFLLPTGVYLNFPVSRNASLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQLCEEAAARRQQLGWEAWLQYSFPLQLEPAARAWGP
GLRAPGRALLVNVKFEGSEESFTFQVSTKDLPLALMACALRKKATVFRQPLVEQPEDYTL
QVNGKQEFLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKSRT
KPPPIPMKKPSSLSLWALERPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSS
EVSVCSEPVWKQRLEFDIHVCDLPRMARLCFALYAVIEKAKKARSTKKKAKKADCPIAWA
NLTLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVCNNPNTESAAALVICLPEVAPH
PVYYPALDKILELGRHGEHGRATEEEQLQLREILERRGAGELYEHEKDLVWKLRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVS
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPQTKELMHLCMRQ
ETYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVVYSNEEAGGDGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A668VNA8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKSKNIKKIFINVKFEASDESFMLQQDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTITKYQEEQGRMCSQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKVPSPKRLHKTVTVKRNYFKLKEIMDNKNYTEFFEDEKELLWKLRTEVRDH
YPESLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLR
KLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASVG
LRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESYL
EALSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLRQ
DMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAA
TAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQ
LFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKI
LCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEALRES
WKTKVNWMMHSLAKDNRP
>A0A8D0AHJ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
VGLENDMTFFLFDQEPKALREDTRRRRRKKAIMSSSCTSMDQISVEFVLPTAARGGNNPD
TLLLEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQV
FQTLDCIRYWRALKKDVGRIQLAPRPQPSDESQQYQRYLNYLIGYDVTDVSNVHDDELEF
TRRKLLTPRRIQLADRDAKLYSMDPWVTRKPLPEHLLSKISNGHILVVIHIGTASQTIKV
SIDNTPAQVLVSFLAKTANKRSLLGIPDNMCEADFVLRVCGREEYLYGDKPLQDFNWIRQ
CLKNGEEIHLVLEAPPDTDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMW
DCNRKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLE
FNIKIKDLPKGARLNLQVVCGKQSQTPNSKGSSSRLLYYVNLLLIDHRSLLRQGEFILHM
WKMPEKSEESSSSINADKLTSATNPDKASAMAVAILLDKYCYPVVLPKSRDVGRDAATGC
EEAEGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLG
SVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDD
DVLRYLLQLVQAVKFEPYHDSALVRFLLKTALRSKRIGHFLFWFLRSEIAQSMHYQQRYA
VLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTREVKAMSADKCDITAQVVFQLRQKLETL
QSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKD
GDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIETVKDATTIANIQQS
VVGSTGAFKDEILCQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMI
TESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQVQPG
GDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLL
DQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A8D0DEF0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MPPAMTDLLDIWAAHSPLAGHALDQITVDFLLPTGIYIQMVVPREATIQHIKLLLWKQAQ
SHPLFSSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRSCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRLSEERMQQVQMMTCTEWLQACFSPQLEPL
AGTAITDGLNDRPADLKVIIHFDQSQDSASLKVPSSCIPSDLMELAVKKWLTTHAPEEEV
WLGQYILRVSHCLEFLCGEQPLIQYKYIRTCMQAKESPHLTLVHTSTVKGMFDKEISAIR
AVVSRKSSNPPLPLPPKRRVPTQLQKYVWDVSSPFKIVLVNGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESSGRSDHTWKDSTLEFDLSVCDLPRMTRLCFAIYAVMDKVKKQKST
KNAHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHSIVFPPFDKILEKAAEIAGASDCVPMGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALMLEAYCRGNIPHIEVLKKQVEALS
KLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGI
NVERCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAN
LDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNTG
DALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLVLRKNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDEDALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C9ZFB6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLLSIKQQLFTEARKYPLYH
LLQEESSYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNLESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYRRYYSDGSPARSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRTGIYHGGEPL
CDNVNTQRVPCSNPRWNEWLAYDIYLADLPRSARLCLSICSVKGRKGAKEEHCPLAWGNV
NLFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFSWFNQTVVFP
DEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDGEQLRSLCSRDPLYELSEQEK
DFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESALELLDCNFPD
PMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFF
WHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQ
KTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDI
MSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLI
EVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTRSCAGYCVAT
FILGIGDRHNSNIMLKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGI
QESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELKTLALEKSQQEALEY
FTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>L8XZZ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tupaia chinensis|TrEMBL
MELIPIEFVLPTSQRNSKTPETALLHVAGHGNVEQMKAQVWLRALETSVAADFYHRLGPD
HFLLLYQKKGQWYEIYDKYQVVQTLDCLRYWKALHRSPGQIHVVQRHAPSEETLAFQRQL
TALIGYDVTDISNVHDDELEFTRRRLVTPRMAEVAGRDPMLYAMHPWVTSKPLPEYLSKK
ISNNCIFIIIHRSTTSQTIKVSADDTPATILQSFFTKMAKKKSLMDIPESQNEQDFVLRV
CGRDEYLVGETPIKNFQWVRHCLKNGEEIHLVLDRAPDPALDEVRKEEWPLVDDCTGVTG
YHEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVL
CQRRTSPKPFTEEVLWNVWLEFSIKIRDLPKGALLNLQIFCGKSPALSGKASAETPSSES
KGKVQLLYYVNLLLIDHRFLLRHGEYVLHMWQISGKGEDQGSFSADKLTSATNPDKENSM
SISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKEL
LWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCN
FSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALVRFLLKRGLRNKRIGHF
LFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSA
EKYDIEKCKVMASKKKPLWLEFRCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMES
IWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKE
KCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYK
SFLGINKERVPFVLTPDFLFVMGTSGKKTSPYFQKFQDVCVKAYLALRHHTNLLIILFSM
MLMTGIPQLTSKEDIEYIRDALTVGRNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLG
IKQGEKHSA
>W8FKV7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tupaia chinensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKISHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETATKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWSEWLNYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIRPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQSQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A4W3JP13|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPAMTDPLDIWAVDSQIPADNSITVDFLLPTGIYIQLDVPREATIDQIKMLLWRQAQTY
PLYTVLGEKDSYMFQCVNQSAVHEELEDESRRLCDVRPFLPVLKLVARNCNRSERLLDSK
IGVLIGKGLHEFDALTDPEVREFRSKMRMFNEEKMLKLQGLSWMDWLKHSFPPELESTAF
NNFEDKLPKENLVVAVQFDSCQENFSFQISPNLNPLDLNELAIRKQLTIHGKENEEFNPR
DFVLRVSGKQEYLFGEQPLIQFRYIRNCVLKGSNPQLTLVDCCTIKEMCDREMSAIGVAL
HRKISNVQVRAGIFHGTELLSKSVVSTEVSGKNDLVWNEILDFEINLCDLPRMSRLCFAV
YGVMDKVKKQKSTKNASKYQTIRKHYPIAWVNTMVFDFRAQLKSGDLDLHCWSSFPDEME
DMLNPMGTVQTNPYSENAASLHIQFQEYSKSVIYYPAFDKGRGGKKLHIELKEIMERDPL
SQLCENEMDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDVAQLQALLQIWIKLCPRDAL
ELLDFNYPDQYVREYAVKCLKEMSDEELSQYLLQLVQVLKYEPYFDCALSRFLLERAQAN
RRIGHFLFWHLRSEMHLPATSLQFGLILESYCRGSFTHIKELSKQMEALSKLKAINNLVK
LSYLKVTRTKVKEVMNTCLKQPVYTEALSDLQSPLNPSVILSKLNVDKCKFMDSKMKPLW
ILYNNKMSGGEPVGIIFKNGDDLRQDMLALQILRLMDMLWKEAGLDLRDALDRAIEEFTL
SCAGYCVATYVLGIGDRHSDNIMVRETGQLFHIDFGHILGNFKSKFGIKRERVPFILTHD
FIHVIQQGKPGNAEKFGRFRQCCEEAYLILRKNGNLFITLFALMLTAGLPELSSVKDIQY
LKDSLALGKSDDEALKQFRQKFDEALRESWTTKVNWMAHIVAKDNRS
>A0A2U3VSW6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Odobenus rosmarus divergens|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>T1D9T8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crotalus horridus|TrEMBL
MELESSDEAVVMRDDNKRRRRRRMKPYCTANTFSSTELISIEFVFPTTSIVLDVATNCTV
EQMKAQVWMQAVEGHQTSELFRKLTPDQFLLLYQKKGQWYEIYDKHQIMQTLDCILYWKV
LQKKVGKIHVIEKPSPSEEVQEFQRQLNYLIGYDVTDVSNVHDDELEFARRRLVTPRTIE
VSCRDPKLYSMHPWTTSKPLPEYLLSRIVNNTIFINIHRGTTSQKIKVGVDDTPEVILQS
FFTKMAKKKSLMNIPEDYSELDFVLRVSGRDEYIVGETPIKNFHWIRQYLKKGEEIHLVL
DEPPDPNQDEVQKEEWPLVDDCTGVSGYHEQLTIQGKDHERVFTISLWDCNRKFRVKVIG
IDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTTAKPFTEEVLWNVWLEFDIKIKDLPKGA
LLTLQIYCGKTPAPSTKGNLHSYDSPSSDPKYKTQLLYYVNLLLIDHRSLLRTGDYVLHM
WKIPGKGEEQGSINADKLTSATNPDKDNSMAVSIVLDKYCHPIALPKHKIASDPQGDRAR
AEMPNQLRKQLEEIIATDLLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQELV
AETYQLLAKRDAWDQSALDVGLPMQLLDCNFSDETVRTMAVQKLEVLEDDEVLHYLLQLV
QAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGC
GKAMLKDFLKQVQVTELLHKVTRDIKAASAEKYDVTPQVITQLKQKLERLQENKFPECFR
VPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTSLSSETIGIIFKHGDDLRQDMLI
LQILRIMASIWEEDSLDLCLLPYGCISTGNKIGIIEIVKDANTIAKIQQSTVGNTGAFKD
EILNQWLKEKCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITGSGNLFHID
FGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLRFQNFQDICVRAYLALRKHS
NLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKHEDDAKKYFLDQIEVCRDKGWTVQF
NWFLHLVLGIKQGVEKHSA
>A0A091E420|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fukomys damarensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKSNRLARDNELRE
NDKEQLRAICTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYC
LVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYL
DNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQ
VEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLR
LEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQ
NQGLDLRMLPYGCLSLGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKN
KGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKF
GYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMM
LGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQH
ALN
>A0A8I6AKZ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rattus norvegicus|TrEMBL
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLD
CLRYWKMMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIVNNCIFIVIHRGTTSQTIKVSADDT
PDTILQSFFTKMAKKKSLMNIPESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRNEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPSLSSKASVETPGSESKGKAQLLYYVNLLLIDHRFLLRHGGY
VLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGKAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSSLP
ESFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKRADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWEAESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDCCVYFTILQ
GCLR
>A0A7L2QNJ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oxylabes madagascariensis|TrEMBL
KMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLY
QLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGF
AIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPK
HIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQL
KLCVLEYQGKYILKVCGCDEYLLEKCPLSQYKVSNYIRSCIMLGRMPNLMLMAKESLYTQ
LPLDTFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYV
RTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAK
EEHCPLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELE
FDWFSNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRLARDSELTESDKEQLRAICT
RDPLSEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQV
>A0A8D2K447|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Theropithecus gelada|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARL
CFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKG
ELLNPTGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKILELGRHSECVHVTEEEQLQ
LREILERRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCS
WPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELT
KFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALS
KLKALNDFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCT
FMDSKMKPLWIMYSNEEAGSSGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRM
TPYGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDR
AIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERV
PFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELS
CSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L0ML79|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amazona guildingii|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GPLHIPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKTA
AKPPPLPKKKPNYGSLWSLEQSFYIQLVQGSKVNADEGMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWQQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAAEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMQSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKNNRQ
>A0A8C9F3X3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pavo cristatus|TrEMBL
VLISLLWKQAHTYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVT
RNCDPGEKLDSKIGVLIGKGLHEFDALQDPEVNDFRSKMRRISEEKIQSLVGLSWMDWLK
HTYPPEQEPVVPENFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLT
IHGKEDEEIDPADYVLQVSGRLEYVFGDHPLIQFQYIHNCVMNRTLPQLTLVECCTIKKM
CEQEMIAIEVAINRKSSNLPLPLPPKKTRATTVMSGISAFTSVFQNRSPGSPRSLLLHAF
TSEIAGLTAFWILPCPHLPLALFPPMPQKDPLSYFNCNLIVFFLKQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEIHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCKYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLAT
GDHSGLIEAVSGSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRATEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C9F3L8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pavo cristatus|TrEMBL
FNNCKYCGRHLEQDGNRYNLNLLWKQAHTYPLFHLLMEIDSYMFSCVNQTAVHEELEDET
RRLCDVRPFLPVLKLVTRNCDPGEKLDSKIGVLIGKGLHEFDALQDPEVNDFRSKMRRIS
EEKIQSLVGLSWMDWLKHTYPPEQEPVVPENFQDKLYSGNLVVAVHFDNCQVGMGDVFSF
QVSPNMNPIKLNELAIRKRLTIHGKEDEEIDPADYVLQVSGRLEYVFGDHPLIQFQYIHN
CVMNRTLPQLTLVECCTIKKMCEQEMIAIEVAINRKSSNLPLPLPPKKTRSELCNVNHSV
WDFCFYFLLLKIYPSWISSLKCNKNGSFHETFNKCFNGLLYQIVFLSSYFNCNLIVFFLK
QLQALLQIWPKLLPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYE
PFLDCALSRFLLERALANRRIGQMLFWHLRSEIHIPAVSVQFGLILEAYCRGSVAHMKVL
AKQVEALNKMKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILS
ELHVEKCKYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKE
AGLDLRILPYGCLATGDHSGLIEAVSGSETIADIQLNSSNVAAAAAFNKDALLNWLKEYN
LGDDLDRATEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKF
GIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLT
AGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYR
S
>A0A6I8NJJ6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ornithorhynchus anatinus|TrEMBL
MPPRPSSGELWGIHLMPPRIIVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLMYDMYIPDLPRAARLCLSICSVKGRKGAKEETP
CLELEFDWFSSPVKFPDMTVIEEHANWTVSRELGFNYSHAGLSNRIARDNELRENDKEQL
RAICTRDPLSEITEQEKDFLWSHRHYCVTTPEILPKLLLSVKWNSRDEVAQMYCLVKDWP
PIKPEQAMELLDCNYPDPRVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVR
FLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEK
LINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRI
MSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDL
RMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYD
AAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRER
VPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMP
ELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C8MLK5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGMVWRNASSEPLYGALSD
ADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFDSQKNHEVNEFRVKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEPGGIK
TKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDYTLQV
NGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQLSKSRSLS
KPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVVTSGE
VNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPLAWVN
TMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIHFPNIRPHP
LYYPHFDKMVTFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQL
VQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGN
IYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLLSPL
NPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDTVGIIFKNGDDLRQDMLTLQMIQL
MEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALL
NWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFL
GNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVN
LFAMMKAAGLPELSSFKDIQYLKCPFQNMVMIW
>A0A8D1WUA4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A4X1TDU0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MCFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDYPLIQFQHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGL
FHGTELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKST
KTINPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMG
TVQTNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAV
LKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQI
WPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALS
RFLLERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALN
KLKTLNSLIKLNAMKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCK
YMDSKMKPLWLVYNNKVFGEDSIGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRML
PYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRA
IEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVP
FILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTS
VKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8D0HV66|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphenodon punctatus|TrEMBL
MELGNYEQTVVMREENKRRRRRMKTHCTTSNLSSMDLIPIEFILPTSNKHTKVPEKLLLE
IAGNCTVEQMKAQIWMRALEMSQTTDFYHKFTPDQFLLQYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGKIHVIQKQKPSEEVEEFQNQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTTRMIEVACRDPKLYSMHPWITSKPLPAYLLKKISNNNIFITVHRGTTSQKIKVSIDDT
PDMILQSFFTKIANKKSLMDIPEDRSELDFVLRVCGRDEYITGDVPIKDFYWIRQCLKNG
EEIHLVLDNPPDPNQDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTTSKPFTEEVLWNTWLEFDIKI
KDLPKGALLNLQIYCGKAQAALATKTNLQTHDSPNSDSKCKTQLLYYVNLLLIDHRFLLR
SGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISVVLDKYCHPIALPKHKITS
DPQGDRTRAEMPNQLRKQLEEIIATDPLNPLTPEDKELLWHFRYESIRHPEAYPKLLSSV
KWGQQEIVAKTYQLLAKREIWDRSTLDVGLTMHLLDCNFSDENVRAMAVQKLDSLEDDDV
LHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVI
LEAYLRGCWKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLKQKLEKLQN
NKLPENFRVPYDPGLHAGALVIEKCKVIASKKKPLWLEFKCADPTALSNETIGIIFKHGD
DLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDAITIAKIQQSTV
GNTGAFKDEILNQWLKERCVIEEKFQTAVERFVYSCAGYCVATFVLGIGDRHNDNIMITE
SGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQAVCVRA
YLSLRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKTEEDAKKYFLDQIEICR
DKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A2U9BK05|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVNQEAELEEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDCNGPHSRALYVYPPNVESSVELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKPLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVGNRDPL
SEITEQEKDFLWRHRQDCANMPEVLPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A6P6R1E3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carassius auratus|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFQPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLETESLE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGNRSDY
VLRVSCRLEFLLEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISIIGSVLAR
KSSNPPLPLPPKKRQPTQLHTCVWKVHSLFRVNLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDTMTIGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSP
RDALELLDFNYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLER
AQYSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVN
ELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGVHVEKCKYMDS
KMKPLWIVYNNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGC
LATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALEKAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
HDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A6P6QFT1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carassius auratus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSPELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLARLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTEADIEQLRQLSNRDPL
SEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSTTLHQWLKDKNRGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A6I9LSJ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Peromyscus maniculatus bairdii|TrEMBL
MELENYEQPVVLREDNLRRRRRMKPRSAVGSLSSMELIPIEFVLPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDHFLLLYQKKGQWYEIYDRYQVVQTLD
CLRYWKMMHKSPGQIHVVQRHAPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVADRDAKLYAMHPWVTSKPLPDYLSKKIANNCIFIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMNIPESLSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
DEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFAEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPALSSKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRHGDY
VLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRALRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGMAMLQDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLETLQNSSLP
KSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVRAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8C2EV41|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLETESVE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDY
VLRVSCRLEFLLEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAIFEKEICTIGSVLAR
KASNPPLPLPPKKRTPTQLHTCVWKVHSLFRINLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTIGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSP
RDALELLDFNYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLER
AQSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVN
ELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSNLHSPLNPNILLAGVHVERCKYMDS
KMKPLWIVYHNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGC
LATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
HDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A2Y9RIX6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Trichechus manatus latirostris|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLV
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWEAWLQYSFPLQLEPAARGWGT
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVERPEDYA
LQVNGKYEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPTPQVQKLR
TKPPPIPVKKPSSASLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVSVCSGPVWNQRLEFDINICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEQCLYMWPFVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
HPVYYPALEKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
YFPEALARLLLVTKWNKHEDVAQMLCLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHVCMR
QETYLEALSHLQSPLDPSTLLADVCSVEQCTFMDSKMKPLWIMYSNEEAGSEGSVGIIFK
NGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQL
NKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGY
CEKAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKF
NEALRESWKTKVNWLAHNVSKDNRQ
>A0A8B6YFW9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Camelus ferus|TrEMBL
MELENYEPPVVLREDNCRRRRRMKQRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VASHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHLVQRSTPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILHSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPNPDLDQVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPILPRNADLTVYVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDHGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIDEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIDYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A2J8KXR3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan troglodytes|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNP
TGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKLPGGMLLASCEWRPELLWMRLHAED
SAPSRMIGVAMPGLGVLPGLVQAPGDAECSCLLQILELGRHSECVHVTEEEQLQLREILE
RRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPV
LSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDR
ALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>D2GX94|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ailuropoda melanoleuca|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRHSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKISNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLLDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIQI
KDLPRGALLNLQIYCSKAPAPSGKGSADTPGSEGKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLEAY
LRGCGTAMLHDFSQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A2K6T7I0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Saimiri boliviensis boliviensis|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLNGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRTKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKSTVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHFSSILAMRDEQSNPTPQVQKPR
AKPPPIPAKKPSSVSLWSLDQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISISDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLHMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
YPVYYPSLEKILELGRHSECVRVTEEEQLQLREILERRGCGELYEHEKDLLWKLRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLGALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSSGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>Q0IHS8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus tropicalis|TrEMBL
MPPIMDHMDIWTADTPLPPDICVDVLLPTGIYVQMDVPRDASISHIKQLLWKHAQSYPLF
HLLLEIDSYMFQCVNHNAVHEELEDETQRLCDVRPFLPVLKLVSRSCNPAEKLDSKIGVL
IGKGLQEFDALKDNEVMEFRSKMRSISEAKIQSLLGLTWVEWLKRTFPPELEPSIQDNIQ
GKLYGGNIVVAIHFENCQDVFSFQVSPNMVPVKVNELAIRKRLTIHGREAEEVDPEDFVL
QVNGRLEFVFGDHPLIQFQYIRNCVMNKALPHLTLVECCNIKKLFDQEMSEIEHAVRRKS
SMHPALPMPLPPKKRGASMKTLNMRDIVWNIVQPYKIILSKGSRLNTEDSVLVRAGLFHG
TELLCKPTMTPEVQGKNDHVWNETLEFEINVCDLPRMARLCFAIYAVLDKPRNKNKTKYQ
TIKKSGKMHFPVAWVNTMVFDYKGQLRSGDHVLHCWSSFPDELEEMLNPMGTVRTNPYTE
NTTTLHIKFHDYSKEPISYPPFDKILEKAAEIARNSDSLSTSGRGGKKLNIELKEIMERD
PLCQLSENEKDLIWTLRYDCRENFPGSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPRD
ALELLDFNYPDQYVREYAVNCLKPMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLQRAL
DNRRIGQFLFWHLRSEVHNPAVSVQFGLLLEAYCRGSVAHMKVLSRQVEALNKLRTLNGL
IKLNAVKLSKVKNKDNMHTCLRENAYKEALMHIQSPLNPSITLSELVVEKCKYMDSKMKP
LWIVYNNRGFGSDSLGIIFKNGDDLRQDMLALQLLRLMDMLWKEAGLDLRIVPYGCLATG
DRCGFIEVVSAAETIADIQLDSSNLAAAAAFNKDALLNWIKECHSGDDLERAIEEFTLSC
AGYCVATYVLGIGDRHNDNIMVRKTGQLFHIDFGHILGNFKSKFKIKRERGPFILTYDFI
HVIQQGKPGNTEKFGRFRQCCEDAYLILRRNGNLIITLFALMLTAGLPELSSVKDIQYVK
DSLALGKKEEDALKQFRQKFDEALKESWTTKVNWMAHTMRKDYKA
>A0A8C3K0L4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calidris pygmaea|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQALSTKTNVQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8J0S934|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus tropicalis|TrEMBL
MKKETLLCRGNMLASGMELDSYEQPVVLRDENQRRRRRMRPHSATSNMFPMEQIPIEFIL
PTSNRCSKVQETMLLEVAGNCSVEQMKAQIWMHAIEKSHNSDFYQRLTPDQFLLQYQKKG
QWYEIYDKHQVIQTLDCIMYWKVLQKTVGKIHIVQKEKIPEEMIEYQKTLNYLIGYDVTD
VSNVHDDELEFTRRRLVTPRMIELSRRDARLYSMDPWVTCKSLPEYLCQRIISNSIFIII
HKGMTSHTIRVSIDDTPDVILHSFFTKMAKKKSLLDISEENSELDFVLRVCGRDEYIIGN
APIKDFHWIRQCIKNGQEIHLVLEKPPDPLMDEVQKEQWPLVDDCTGVTGYHEQLTIEGK
DHEKIFTISLWDCNRKFRVKIIGIDIPVLPKNTELIAFVEANIQHGQQVLSQRRTTCKPF
TEEVLWNSWLEFDIKIKDLPKGALLNLQIFCGKAPTASNKSIVQSPESTASDSKCKNQLL
YYVNLLLIDHRFLLRQGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKETSMAISISLD
KYCHPVALPKHKLVCDPELERPRTEMPNQLRKQLEEIIATDPLHPLTPEDKELLWHFRSE
IVKHPEAYPKLLSSVKWGQQEMVAKTYQLLSKREAWDDCSLDVGLTIQLLDCNFSDENVR
AMAVQKLESLQDDDVLHYLLQLVQAVKFEPYHDSALSRFLLKRALQSKRIGHFLFWFLRS
EIAQSMHYQQRFAVILEAYLRGCGKAMLDDFTRQVQVTEILHKVTMEIKSVSAEKYDVTS
QVITQLRQKLEKLQNSKLPDKLPDSFRVPYDPGLRAGSLVVEKCKVMASKKKPLWLEFKC
SDTTALSNETIGIIFKHGDDLRQDMLILQILRIMGSIWEAESLDLCLLPYGCISTGNKIG
MIEIVKDATTIAQIQQSTVGNTGAFKDEVLSQWLKEKCPIEEKFSAAVERFVYSCAGYCV
ATFVLGIGDRHNDNIMVTESGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGT
SGKKTSQYFNKFQDVCVKAYLALRHHTNLMIILFSMMLMTGMPQLTSKEDIEYIRDSLTV
GKNEESAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3P9JA59|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MPPAMTDLVDIWAAHSPLDGQAPVHVTMDFLLPTGIYIQMEVPREATIQHIKLLLWKQAK
SFPLSSFLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVFRLVTRNCGRAERLLD
SKIGVIIGKGLHELDGINDQEVKDFRSKMQRLSEERMQRVQMMSFTEWLQACFSPQLEPS
AGTAIADGANDWPADLKVIIHFDQSQDSTSLKVLSSCTPSVLIEIALKKWQTTHAPEEET
NKDKHILRVSQCLDFLCGDHPLIQYKYIRSCLQAKESPHLTLVHINAVKAIFDKENAAIG
AVVSRKSSNPPLPLPPKKRAPTQVQTCVWDVSRPFKVVLVKGSTVNADENAKVQVRAGLF
HGTELLCKPAVSSESSGRSNHSLENNTLEFEISVCDLPRMTRLCFAIYAIMEKVKKKSYK
NPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDTILHCWSSFPDELEEMLNPIGT
VRINPYPENATALHIHFPDYGPHPIVFPPFDKILEKAAEIAGSSDSTPIGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRLDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVSCLRDMSDEELLQYLLQLVQVLRYEPYYDCALTH
FLLERAQKNRKIGHFLFWHLRSEIHMPAVSIQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNTRSKTKEAMLTKEAMITCLKQSGYSEALSDLHSPLNPNVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLMSSDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLVLRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKSDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A3Q7Q5E0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinus ursinus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECFKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVDCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6P9DI72|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pantherophis guttatus|TrEMBL
MPPAMADILDIWAIDSHIAADSSISVDCLLPTGIYISLDVPRDATICHIKQLLWKQAHSY
PLFHLLLEIDSYMFSCVNQTAVREELEDETRRLCDIRPFLPVLQLITRSCDPGEKLDSKI
GVLIGKGLHEFDALQDPEIKEFRIKMRQISEEKMQSLMGLSSMNWLKHTYPPELEPAIQD
NFQDKLYGGNIVVAIHYENCQDVFSFQVSPNINPIKLNELAIRKWLTIHGKEDEEVDPYD
YVLQVNGRLEYVFGDHPLIQYQYIHCCVINRALPQLTLIECSTIKTMYEQEMIAIEVAVN
RKSNNLPLPLPPKKSRLTQSVWEIGHPFKILLVNGSKLNTEETAKVHIRAGLFHGNELLC
KPIVSSEIAGRNDHVWNEPLEFDINVCDLPRMARLCFVVYAVMDKMKNKKSAKALNPSKY
QTMRKAGKVHYPVAWVNTMVFDFKGQLKTGDLLLHSWSSFPDELEEMLHPMGTVQTNPYT
ENATTLQIRFQEYSKCPIYYPPFDKILEKAAEIARNSDCSGMPGRGGKKFYIELKEIMER
DPLSQLCENEMDLIWTLRFDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPR
EALELLDFNYPDQYVREYAVACLRQMSDEELAQYLLQLVQVLKYEAFLDCALSRFLLEKA
LANRRIGQMLFWHLRSEMHIPAVSLQFGVILEAYCRGSVPHMKVLSKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDTMHTCLKQSAYREALSHLQSPLNPSVLLSELCIEKCKYMDSKMK
PLWIVYSNKAFGADLVGIIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRLLPYGCLAT
GDYSGLIEVVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNTGEDLDRAIEAFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQCCEEAYLILRRHGNLFITLFALMLTAGLPELTSFKDIQYL
KDSLALGKNDDEALKQFKHKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3B1K160|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLISVKQQLFAEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPSVESSPQLPQH
IYCKLDKGRLIVTIWVVVSPSNAKQKYTLKIAHDCLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKVCVSIYMHNLVFSVLTKH
>A0A0Q3LWB1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amazona aestiva|TrEMBL
MELEDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAANCTVEQMKAQIWMRALEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQNPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKVKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDPKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADXLTSATNPDKESSMAISIVLDKYCHPIALPKHRITSD
PQGDRIRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEIWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLXLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFXKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIVQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEDDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A671L2C5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCFFIPIFCVLESFIIGSHHEFDSQKNHEVNE
FRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQSGKSHSGKKILVNVKFEGS
EETFVLQQDPQDLPMFLKRNALRKKSTVFRPAKQEKPEDYTLQVNGRWEFIYGKYPLCQF
KYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRTRAQSKPPPLPLKRQNTSSLW
SIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSNEVSVCSEPVWDQKLVF
DIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFS
LSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKLNELGMNC
EKVVATKEEHLKLREIVDNKNYTEFFEDEKELLWKLRKEVRQRYPESLPKLLLITKWNKH
EDVAQMVCLLRKWQELPAIHALELLDYSFPDPHVRSFTIRCLRNLRNDELFQYLLQLVQV
LKYESYLDCDLTCFLLERALSNKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSIFL
IKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPS
IVLCELCADKCKFMDSKMKPLWLMYKDKYDHVGIIFKNGDDLRQDMLTLQMIQLMDVLWK
TEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSK
NPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSK
FGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMK
AAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSFAKDN
R
>A0A7J8HDT0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Molossus molossus|TrEMBL
MELENNEQPVVLREDNRRRRRRMKPRGSAASLSSMELIPIEFVLPTSQRTSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYQRLSPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHMVQRRSPSEETLAFQRQLTALMGYDVTDVSNVHDDELEFTRRRL
VTPRMTEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVLADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPAQDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESIFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKACAETPSSESKGKVQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSICILLDNYCHPIALPKHHPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QKIVAKTYQLLARKEAWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSSLP
KSFRVPYDPGLKAGALVVEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQEVCAKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A671T670|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MEHQASDDEPPVVRREENKRRRRKMKAFPSTSAVSTDHIAVEFVLPTTNKNSRNPDTLHI
DVTGNWTVEQVKVQIWHRVVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVVRTQPTEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDPKRYSMDPWMTTKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFAKITNKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKN
GEEIHLVLERPPDPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDQYCYPVALPKSKDSPNSEMEGERG
QREMPNHMRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEA
VTITHRLLERSTVWDRSSLDVGLALQLLDCHFSDENVRTMAVRKLETLAGDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRG
CGEAVLQDFRKQVEMTEALHKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDSF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFMGISKERVPFVLTPDFLYVMSTTGKKSSPHFLQFQSVCLKAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEMCRDKGWTVQ
FNWFLHLVLGIKQGVEKRSA
>A0A671T363|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPAKTDQLDLWAESGLDGDVQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSCGEWLRSCYSTQLGTGSLE
NLIDKHEGVIKITMHYDQSQVCSVILVLSLHCTVTELMDQALKKWQTTHGPEEDIGTRSD
YVLRVSGRFEFLFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLA
RKTSNPPLPLPPKKRPPTVSTLSVFPALQLIKGVPSFVHLAAPNSNAKIQVRAGLFHGTE
LLCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHL
NKYQTILLKLTVLCVMGDYQNNIWGSHAPQGRGGKKFYIELKEIMERDPLSQLCENEKDL
IWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQ
YVREFAVICLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWH
LRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVSELIKLGTIKTKTKQ
AHLKEAMMTCLRQTGFIETLSDLQSPLNPNILLAGRCKYMDSKMKPLWIVYNNKLLGGDT
VGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADT
IANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGD
RHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKF
GNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALK
QFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A1V4K3Z7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Patagioenas fasciata monilis|TrEMBL
MEFARLKFTRGNNKIYCAILLGNKGKHLQSREEGKSSEVTTLLRRVGKATDTRSHLVRVK
QEQVLWSHVIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHSYPLFHLLME
IDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKIGVLIGKGL
HEFDALQDPEVKDFRAKMRKISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPESFQDKLYN
GNIVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPADYVLQVSGR
LEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAVEAAIHRKSSNLPL
PLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLCKTIVSTEI
SGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKYQTIRKAGK
VHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYTENATALHI
RFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMTGRGGKKFYIVLKEIMERDPLSQLCE
NEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPREALELLDF
NYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQ
MLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAMK
QSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKPLWIVYNN
KMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATGDHSGLIE
AVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSCAGYCVAT
YVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGK
TGNIEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGK
SEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6P4Z858|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Branchiostoma belcheri|TrEMBL
MPPSSGELWGMHLMPPKVPVDCLLPTGIMITLDVPREATLEHIKGDLWREARKYPLFHKL
QDETMYIFISITQEAEKEEFYDETRRFCDLRLFQPWLKVTEPRGNREEKILNSEISLAIS
MPVTEFGTVKDPEVMDFRRNILTTCLQSVQERDSDGLTGQSLYVYPPIIETDPSLPRNLD
AKLDIGHIIVAIWVLTRDNERQKYTVKVSKTSLPEDVIAGAIKKKTRTMGLTPEQQQQCI
EEYQNSYVLKVCGAEEYMLGRYPIIQYKYIRMCLSRTRFPNLMLMSKEVVYASLPESTFH
LPSYARRGSSAVLNPSNGTAQIRCIYDIQSPLRIKILCATYVNVKEHDKIYVRSGVYHGG
EPLCTPVNTNRVPCSNPLWNEWLEYEIAIPDIPRSARLCLSICSVNRKKGKKEDHCCLAW
GNINLFDYQGNLQNGKYQLNMWSVPHGMDDLLNPIGSTGQIPARXDTPCLDLEFDRFAHV
VKYPNDQQIEEYAKWIANVNSEGNILRGTTSSASNLHGASNSYAENGDSELEQLHEILRK
DPLSDFSEQEKDLVWKMRKRCQEIQDSLPRLLQSCKWSSREDVSQMYMLLENWPQVSPET
ALELLDCTYADLKVRKFAVDCLRKTMTDDQLSQYLLQLVQVLKYEPYLDNPLARVLLERS
LLNQRIGHFFFWHLKAEMSNKNVRIRFGLLLEAYCRACGAYLKNLVRQVEAQEKLTMLTE
TLQEREKEKKDTTQRERLKFLGEKINQEDYLEALQNFPCPLNPSHLLGTLLIKECKVMKS
AKRPLWLNWENPDPMADLYFLNQMIIFKNGDDLRQDMLTLQMIRIMDNIWQTEGLDLRML
PYQCLSAGNCVGMIEVVRNAKTVMQIQRMSGITGTLQLRSDSLHEWIKSKNKGDRYDRAI
EAFTLSCAGYCVATFILGIGDRHNDNIMVNEEGQIFHIDFGHFLGHFKKKFGYKRERVPF
VLTEDFLKVIAKGGDYQKSKEFKSFQELCRRAYLYLRKHANLFIVLFTMMLSTGIPELQS
FDDIEYLRKTLAVEMTDTEALQYFSSCFNEAYSRSYSTKVDWMFHGIKQSR
>A0A6P6QZH0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carassius auratus|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFQPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLETESLE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGNRSDY
VLRVSCRLEFLLEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISIIGSVLAR
KSSNPPLPLPPKKRQPTLHTCVWKVHSLFRVNLVKGNKVNAEDAAKIQVRAGLFHGTELL
CKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNK
YQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPY
TENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDTMTIGRGGKKFYIELKEIMER
DPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPR
DALELLDFNYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERA
QYSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNE
LIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGVHVEKCKYMDSK
MKPLWIVYNNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCL
ATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALEKAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTH
DFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQ
YLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A2K5RRE2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cebus imitator|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSAAASLSPMELIPIEFVLPTSQRSCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKAMHRSPGQIHLVQRRAPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKYLMDIPESQSERDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKAPAESPSSESKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCYPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIETLQKVTLDIKSLSAEKYDVSSQVIAQLKQKLENLQNSHLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSKETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEDKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSQHFQKFQDICVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A672UTG4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMNIFVNV
KFQSGGVKHNLFSLCWCLTVYAVLLGLQESFTFQISPNEFPITLMSYAIKKQATVFRHET
LEKPEDYTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNC
ITSPPKTATKPPPLPKKKVKGGSDPAGSTSNHPLMEMLSLCGNNSWFSLPSSGQLVVQAG
LFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARS
TKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTE
SAAALVICFPSVASHPVYYPSFEQVGTFPSFAQKLQLKEILERRSHTELYEHEKDLVWKM
RYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGS
FAVNSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSE
MHVPAVALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEM
MHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVG
IIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIA
NIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFER
FRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHF
RLKFNEALRESWKTKVNWLAHNVSKNNRQ
>A0A852FJ63|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Peucedramus taeniatus|TrEMBL
MELEDYEQPVVMRDENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQRQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIVIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSSSDAKCKTQLLYYVNLLLIDHRFLLRT
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKGADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3P8V779|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cynoglossus semilaevis|TrEMBL
MPPGKYGMQEEWEKEGVQEIVMDFLLPTGIFLKFPVSRNDTIKNIKKMVWRNARSEALFS
ALGDPDAYVFTCINQTAEREELEEESRRISDVQPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNHEVNEFRLKMRTFCEDKALEQQRLPWQQWMEYSFPTDLEPTAFRTSL
REHGARSLTSGLKCLPQESFMLQQNPQDNPGALIRSALKKKATVFRSMRQEPEDYTLQVN
GRWEFIYGKHPLCQFKYIFSCLTNGQNPHLIMVHRSTISKYQEEQGRMCSQVFKSHSSSR
PPPLPLKKLVVQAGLFHGSELLCKIVTSSEVTVCSEPLWDQKLNFDINVADLPRMSRLCF
ALYAVIEKNKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEVILSMWPSVPGTVHHL
LLPIKIFEKNPNLDSAAGLLIRFPNIRPHPLYYPALDKISEVETNGDIAHVTKEEHMKLK
EIMDNKNYTEFFEDEKELLWKLRAEVRNHYPESLSKLLQITKWNKREDVVQMVSLLRNWP
DLPAIQALELLDYSFPEPAVRYFTIRCLRMLSDDELLQYLIQLVQVLKYESYLDCDLTTF
LLERALSNKRIGHFLFWHLKSEMHVPSVTLRFGLILEAYCRGNIHHIKLLSKQNEALGKM
KALSDFVKSGSQKLTAEDLKMCIRQESYLEALSDILSPLNPSIILTEICADKCRFMDSKM
KPLWLMYKNNLSQGDMVGIIFKNGDDLRQDMLTLQMIQLMETLWKKEGLDLRDKLDQAIE
EFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFI
LTYDFVHVIQEGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFK
DIQYLKDSLALGKTEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A803YMK6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Meleagris gallopavo|TrEMBL
FCFMSRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQ
YEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLIN
SQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPM
AKGLGTGLFINFQPCACSFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYTLQVN
GKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQVNSIANPPKMAVKPP
PLPKKKTGQVPVDSWYSYFFSPQLVVQAGLFHGNEMLCKMVSSSEVNVCSEPVWKQRLDF
DINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVSKDCPIAWVNVMLFDYKDQLKT
GECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNVASHPVYYPSFEKEICS
ATDSSQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLTITKWNKHEDV
AQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQYLLQLVQVLKY
ESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKV
LMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQETYLEALSHLQSPLNPSIIL
TEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDVLWK
QEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSK
NPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTK
FGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYMILRRHGPLFLHLFALMK
AAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDN
RQ
>A0A8C7MY04|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLTNIKQQLFTEARKYPLYP
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFEQLKDPEVQDFRRSILGVCREAMEEREGGGAETQALYVYPPNVESAPRAATT
HLLQTGQGLKYTLKISHDSLPEQLIAEAIRKKTRSMHLSAQQLRLCVQEYQGQYILKVCG
CDEYLLEKYPPHQYKYIRSCITVGRLPHLMLVSKDSLYSQLPGSGFVAPSYSRRTPQPSP
CPGGGDPSSPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQ
RVPCSNPRWNEWLSYDIYMTDLPHSARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYKD
TLVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFSWFNQVVLFPDEQQIEE
HANWTISRELGYNYSLGLSSRLACDSSVSAADGEQLRSLCSRDPLYELSEQEKDFLWRHR
HYCVNIPESLPKLLLSVKWNSRDEWSQMYCLLRDWPLMQPEKFALRCLVQGLTDDKLSQY
LLQLVQVCLSVCLCTWTNPLARFLIKKALTNQRIGHFFFWHLKSEMHNKTVSRRFGLLLE
AFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQKTQMKFLVEHMSRPDYMESLQ
GFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWDNPDIMSELLFTNNEVIFKNGDDLRQ
DMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVKNSYTIMQIQCKGGLKGA
LQFNSHTLHHWIKDKNRGEGYDRAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQL
FHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQECTKTKEFERFQEMCYKAYL
SIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKSQQEALEYFTKQMNDAHHG
GWTTKMDWIFHTIRHMPNEH
>A0A8C0ETU6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C4AX13|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPTMMDVLDLWAELGEVEHVSVDFLLPTGLYIQMEVPREATIQHIKQLLWKEAAGYPLF
TLLGAMEGHMFECVNQTAVHEELEDETRRLCDVRPFLPVLRVVTRSGGHNERLLDSKIGV
LIGKGLHELDSLQDQEIKDFRTKMQQISKEKIQRIQVMSWEEWLRTHFSPQLEVGQVDGM
IEKLCEDGIKVTMHYDQSQDTVSVRVDVSCTVRTLLELALRKWANTHGHNNSSCLSDYIL
RISSKLEILFEEHPLIQYKYIRECLLAQESPHLTVMHSSVLRGMFERELGCIASVCGHKQ
SNAPLPLPPKKRPPSQMHTCVWDVQSQFKITLVRGIKVNTEESAKVYVRAGLFHGAELLG
KPAVSSDSSGRLEHLWNTTLEFDVAVSDLPRMSRLCFAIYAVMDKVKKQPKSIKTPHSKY
QTIRKAGKVHYPIAWVNTMVFDYKGLLKTGDVVLYCWSSFPDELEEMLNPIGTVQTNPYT
ENATAIHITFPEYSQISVIFPPFDKGRGGKKFHIELKEIMDREPLSQLCENEKDLIWTLR
YDCRENFPQSLPKLLLSVKWNKHEDMAQLQALLQIWPTLSHRDALELLDFNYPDQYVREY
AVNCLRDMSDEELSQYLLQLVQVLRYEPYYDCALSRFLLERSQLNRNIGHFLFWHLRSEM
HMPAVSVQFALILEAYCRSSIPHIEVLKKQVEALNKLKAVNALVKTGAVKSKARTKDSHL
KEAMLTCLRQSGFTETLSDIHSPLNPSVLLAEVNVDRCKYMDSKMKPLWIVYNNKLLGGE
TLGIIFKNGDDLRQDMLTLQILKLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSAD
TIANILKTSSNMAATAAFNKDALLNWLKEKNSGDTLERAIEEFTLSCAGYCVATYVLGIG
DRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTANTEK
FGSFRQYCEEAYLVLRRNGNLIITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEAL
KQFRQKFDEALRESWTTKVNWMAHHIAHAS
>A0A8C0F8R5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIESLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
NLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGSSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C0FTD3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLERSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGDQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDQYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C0FNY8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQVHKALWNLPMNLYLCFPSQSVWDISNPFKIILLKGNKL
NTEENAKVHVRAGLFHGTELLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFA
VYAVMDKMKTKKSTKHYPVAWVNTMVFDYKGQLRNGELVLHSWSSFPDELEEMLNPMGTV
QTNPYTENATALHIRFQEYSKQEDCLEKGGGKKFHIVLKEIMERDPLSQLCENEMDLIWT
LRYDCRENFPQSLPKLLLSLKWNKLEDVAQLCIVLLHETEKLGDTLAVETNLSLLDLYSV
TDCFYVPHSSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQMLFWHLRSE
VHIPAVSIQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAMKQSKAKGKDA
MHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKPLWIVYNNKMFGGDLVG
IIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATGDHSGLIEAVSSSETIA
DIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGR
FRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQF
KQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C0FPK3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQVSLMAAKPPPLPKKKPNYGSLWSLERSFYIELVQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNP
MGTVQCNPNTESAAALVICFPSVASHPVYYPSFEGPVCELYGCADVPFLGKGLIPLFLLL
PGKGLCGQLALCMLFSCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQA
LAKLLIITKWNKHEDVAQVRMLGLATWPELPVLNALELLDFSFPDQYVGSFAINSLKKLT
DHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRF
GLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHVCMKQETY
LEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLR
QDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMA
ATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETG
QLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYM
ILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRE
SWKTKVNWLAHNVSKDNRQ
>A0A3Q7TAY4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vulpes vulpes|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNDFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPNDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKNI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNKAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3P9IVJ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MHPGIYGMLEEWEDGDQEINMDFLLPTGIFLKFPVSRNDTIKHIKEMVWRNARSEALFSG
LGDPDGYVFTCINQTAEREELEEEFRRIRDVKPFMCVLRLVAREGNRQEKLTNTQITQLI
GKGLHEFETQKNHEVNEFRTKMRTFCEEKALERQYLPWQRWLEYSFPCDLEPCRTPSGFG
SVKMKSSKIFINVKFEASDESFMLQQDCHDLPVALMKSALKKKATVFRSLRQEPEDYILQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPQVTMVHHSTVSRFQEEQSRMCNQMFKSRSL
SRPPPLPLKRQNTSSLWSINEPFYIQLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTS
LDVTVCSEPLWDQRLEFDINVCDLPRMSRLCFALYAVIEKTKKPKSTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSMWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRP
HPLYYPSLEKIIDFERNGDVACTHKEEHLKLKEIMDNKHYTEFFEDEKDLLWKLRTEIRE
HYPENLSKLLLVTKWNKREDVVQMVSLLKKWPDLPAIHALELLDYSFPDPAVRSFTVRCL
RKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASV
SLRFGLILEAYCRGNIHHIKILNKQNEALAKMRALSDFVKSGSQKMTVEDLKLCIRQETY
MEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNPSTPGDMVGIIFKNGDDLR
QDMLTLQMIQLMENMWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQLNSSNSA
ATAAFNKDALLNWLKSKNPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYK
ILCRNGMLFVNLFAMMKAAGLPELTCFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDNRA
>A0A8C5I421|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
MPPGKYGMQEEWEKEGDQEILMDFLLPNGIFLNFLVSPNDTIKTIKKMVWKNARNEALFN
GLGDPEGYVFTCINQTAVREELEEESRRIRDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRSKMRSFCEEKAQKRQGLPWQQWMEYSFPCDLEPCSAKSKN
KKKIFINVKFEASDESFMLQQEPQDLPLALMRSALKKKATVFRSLRQEPEDYTLQVNGRW
EFIFGKHPLCQFKYIFSCLRNDENPQLTMVHHSTISKYQEEQGRMCNHIYRSCAMSRPPP
LPQKKNTSSLWAINKPFNIHLLQGSRVNADEGMKLVVQAGLYHGSELLCKVVTSSEVTVC
SEPLWDQKLDFDINVADLPRMSRLCFALYAIIEKAKKPRGTKKKNKKADCPIAWVNTMVF
DHKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFPNILPHPLYYP
PLDKVLICVTEENGETEIMDNKNHTEFFEDEKELLWKLRTDIRDCYPESLSKLLLITKWN
KREDVVQMVSLLESWPELPAIHALELLDYSFPDPAIRSFTIRCLRKLSDDELLQYLIQLV
QVLKYESYLDCVLTTFLLERALANRRIGHFLFWYLRSEIHVASVSLRFGLILEAYCRGNI
HHMKVLTKQNQALVKMKALNDFVKSGSQKMTVEDLRLCVKQESYMEALSDLLSPLNPSVI
LAEICADKCRFMDSKMKPLWLMYRNPWPHADMLGIIFKNGDDLRQDMLTLQMIQLMENLW
KKEGLDLRDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLG
NFKRKLGINRERVPFILTYDFVHVIQQGKTNNSEKFERFREYCERAYKILCRNGTLFVNL
FAMMKAAGLPELTSFKDIQYLKDSLALGKSEDEALKNFKVKFTEALRESWKTKVNWMMHS
LAKDNRP
>A0A8C5EKI6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
MPPAMTDLLDIWAPHSPLAGHTLAQITVDFLLPTGIYIQMSVPREATIQHIKLLLWKQAQ
MFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRISEERMQQVQMMTCTEWLQACFSPQLEPA
ASAIISDGVSDRPTDLKVTIHFDQSQDSASLKVSWSCTSAELMELALRKWLSTHGPEEDA
CRGQYVLRVSHCLEFLCGDHPLIQYKYIRSCLQAKESPHLTLVHTRTIQAMFDKEISAIG
SVVSRKTSNPPLPLPPKRRVPTTCVWDVSSPFKIVLVKGSKVNAEESAKVQVRAGLFHGT
ELLCKPSVSSESNFRSDHTWKDSTLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNA
HINKYQTIRRAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQ
TNPYTENATALHIHFPEYLSHPIIFPPFDKVRHPVGRGGKKFHIELKEIMERDPLSQLCE
NEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQVLLQIWPKLSPRDALELLDF
NYPDQYVREYAVGCLRDISDEELLQYLLQLVQVLRYEPYYDCALTHFLIERAHGNRVIGH
FLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIK
NARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSIQLSGINVERCRYMDSKMKPL
WIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRVVPYGCLATGD
RAGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALERAIEEFTLSCA
GYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIH
VIQQGKTGYTEKFCNFRQNCEDAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKSDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7L1AHZ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gymnorhina tibicen|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGT
GSLQIPTKNIFVNVRFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNHPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKAPKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8D3D0T5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPGKYGMQEEWEKEGVQEIMMDFLLPTGILLKFPVSRNDTIKSIKKMVWKNARSEALFC
GLGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRAEKLINTQISLL
IGKGLHEFEAQKNHEVNEFRTKMCIFCEEKAQERQMLPWQQWMEYNFPCDLEPCCTPPHS
GSLKSKNTKKFFINVKFEACDESFMLQQDPQDHPVALMRSALKKKANVFRSVRQEPEDYT
LQVNGRWEYIYGKHPMCQFKYIFSCLRNGQNPHLTMVHHSTISKFQEEQGQMCSQEYKSR
SLSRPPPLPLKKLNTSSLWSITEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFANI
RPHPLYYPPLDKINDIERNGDAASVTKEEYMKLKEIMDNKNYTEFFEDEKELLWHLRTEV
RDRYPENLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAIRSFTIR
CLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVA
SVTLRFGLILEAYCRGNIHHIKLLTKQNEALSKMKTLSDFVKSGSQKLTAEDLKLCIRQE
SYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNNWAPEDMVGIIFKKGDD
LRQDMLTLQMIHYWMIPYGCLSTGNKMGLIEVVENSDTIANIQRNNSNRASLTQRLDKLD
QAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRER
VPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPEL
TSFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A673IF36|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSAELPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKITHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDEYLLEKHPLSQYKYIRSCITLGRLPHLMLVSKDSLYSQLPSS
GFMAPSYSRRTPQPSPCPGGGDPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDEQQIEEHANWKSVLEMECGFSSSRLVCDSSISQADAEQLRTLCSRDPLYE
LSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVHNLDIFLRWKNAVLQMLETWLS
KERLLSNSTPRFLTDDEELTEQPSSLRQCSRLLYAEVLCLIINTSVFSEFMMSPSSPITE
TADWLMKLILHSDWLLQTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIM
SSAKRPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLR
MLPYGCLSIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIRDKNKGEAYDR
AIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERV
PFVLTQDFLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPE
LQSFDDIAYLRKTLALEKNQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A8C9AJZ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Prolemur simus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSCNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARGWGA
GTLRLPNRAFLVNVKFEGSEESFTFQVSTKDAPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGRHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQGQKPR
TKPPPIPVKKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARL
CFALYAVIEKAKKARSTKKKSKKAVGPRASQEGCGPRRARAAPGGPLPPRLSQSGHLPCL
GDSRPTRNIWPGPLILELGRHSECGRVTEEEQLQLREILERRGSGELYEHEKDLVWKLRH
EVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFA
IKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTRFLLDRALANRRIGHFLFWHLRYSEM
HVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKASSQKTTKPQTKEMM
HVCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEQAGGNGCVG
IIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIA
NIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFER
FRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHF
RVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C9B0W2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Prolemur simus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSCNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARGWGA
GTLRLPNRAFLVNVKFEGSEESFTFQVSTKDAPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGRHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQGQKPR
TKPPPIPVKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVICLPEVAP
HPVYYPALEKILELGRHSECGRVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTRFLLDRALANRRIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKASSQKTTKPQTKEMMHVCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEQAGGNGCVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C9ASJ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Prolemur simus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSCNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARGWGA
GTLRLPNRAFLVNVKFEGSEESFTFQVSTKDAPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGRHEYLYGSHPLCQFQGQKPRTKPPPIPVKKPSSVSLWSLEQPFCIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKAVGPRASQEGCGPRRARAAPGGPLPPRLSQSGHLPCLGDSRP
TRNIWPGPLALQEPGGSSLGGDEGPVLMGTMLGMRAGAEGSTSSLVVASRPGSLAGLAQA
LGGPEHGRLLQILELGRHSECGRVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQ
EHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKS
LRKLTDDELFQYLLQLVQVLKYESYLDCELTRFLLDRALANRRIGHFLFWHLRYSEMHVP
SVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKASSQKTTKPQTKEMMHVC
MRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEQAGGNGCVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8J6GR73|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microtus ochrogaster|TrEMBL
MELKNYEQPVVLREDNLRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDHFLLLYQKKGQWYEIYDRYQVVQTLD
CLRYWKMMHKSPGQIHVVQRHTPSEETLAFQKQLTSLIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDARLYAMHPWVTSKPLPDYLSRKIANNCIFIVIHRSTTSQTIKVSADDT
PGAILHSFFTKMAKKKSLLNIPESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
DEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCCKSPALSSKASAETPGSESKSKAQLLYYVNLLLIDHRFLLRHGDY
VLHMWQITGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGMAMLQDFTQQVQVIEML
QKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSSLPKSFRVPYDPGLKAGTLVIEKCK
VMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDL
CLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKAF
VIDSAALCAWRATGIHTPPPQFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGN
LFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVKAYLA
LRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKG
WTVQFNWFLHLVLGIKQGEKHSA
>A0A8C0V5V6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyanistes caeruleus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVRKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEIWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A851WDG8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Corvus moneduloides|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSVSVDFLLPTGIYINLDVPRDATISQIKQLLWKQA
HSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTTVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGHLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A669BCQ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MDRQQIQVSDEESQVPREESRRRRRKKAITSSCSNSMDQITVEFVLPTAARGGSGSDTLQ
LDVAGNWTVEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTCKPLPEHLLSKINNGHILVVIHIGTASQTIKVSID
DTPTLVLVSFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLK
NGEEIHLVLEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKQPQIPNSKGSSYQESTAGSSSLDGKTKSRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLP
KSRDVGRDWAVGGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHE
CMRVPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVR
SMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSKHYQQRYAVLLEAYLRGCGENMLQDFRKQVDMTEALQKVTREIKTMSADKYDVTP
QVVFQLRQKLENLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADST
TLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKK
SSPHFQKFQVLFSMSIQYRCRNTHVPFLNSCRFMQTPVSHICLYEHPLCFRTCA
>A0A669DMZ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKSKNIKKIFINVKFEASDVSSSVDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQVN
GRWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTITKYQEEQGRMCSQVYKSRSLSR
PPPLPLKKVRVCKSSTNNHLHTKVLKSSASKPHVLPPSNHYCVSVVPLQLVVQAGLFHGS
ELLCKVVTSSEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKN
KKAVSDCPIAWVNTMVFDYKDQLKTGEFHLSTWPDLLNPMGTVEKNPNVDSAAELLIHFP
NIRPHPLYYPPLEKVPSPKRLHKTYFKLKEIMDNKNYTEFFEDEKELLWKLRTEVRDHYP
ESLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLRKL
SDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASVGLR
FGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESYLEA
LSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLRQDM
LTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATA
AFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLF
HIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILC
RNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEALRESWK
TKVNWMMHSLAKDNRP
>A0A669BHV6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKSKNIKKIFINVKFEASDESFMLQQDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTITKYQEEQGRMCSQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKVPSPKRLHKTVTVKRNYFKLKEIMDNKNYTEFFEDEKELLWKLRTEVRDH
YPESLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLR
KLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASVG
LRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESYL
EALSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLRQ
DMLTLQMIQLMENLWKKEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIR
ETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCER
AYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEA
LRESWKTKVNWMMHSLAKDNRP
>I3KN90|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRARLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVCGKVALSLWPVPHGLEDLLNPIGAAGSNPNKETPCVELEFS
WFNQIVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSSGDAEQLRSLCSKDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLMLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A8C8H208|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MEQQVGDEEEPQPVVLRAEIRRRRRKMKAFTSTLSVAVDQIAVEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCVRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELSDRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPENVCEADYVLRVCGREEYIYGNHPVRNFHWVRQCL
KNGEEIHLVLELAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVYTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNAWLEFN
IRIRDLPKGARLSLQVSCGKAQTQISKGGSGSGSGSHDGSKTKSRLLYYVNLLLVDHRSL
LRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYPVALPKSRD
GKAAGGEGREAEGGERGQREMPNHLRKQFEVIVETDPLHPLSQEDKELLWHFREECMRHP
RAYPKLLGSVLWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSMAVR
KLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQS
MHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQVVFQ
LRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTTLSSD
TIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDAT
TIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLGVGD
RHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHF
QKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEEAQR
HLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A3P9PLB6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia reticulata|TrEMBL
MDRQQIQVSDEEREVAREESRRRRRKKAITSASSASMDQISVEFVLPTVGRGGSSPDSLL
LEVAGNWTVEQVKAQVWMKAVSLNLCPDFYQRFCPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPTDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPNLYSMDPWVTRKPLPEHLLSKVNNGYILVVIHVSTSSQTIKVSID
DTPSQVLASFFAKTTNKRVLLGIPEHLSDEDFVLRVCGREEYLYGEKALQSFNWIRQSLK
NGEEIHLVLETPPDQELDLVQREDWAQVDDCTGVAGTHEQLTIAEKDHERVFTISMWDCN
RKFRVKVLGIDIPTLPKVPEFTVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKQPQTPNSKSSYHDNTAGSSTLEGKTKNRLLYYVNLLLIDHR
SLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPK
SREVGRDCGASGEEADGGERGQREMPNHLKKQFAAIVSTDPLHPLSPEDKELLWHFRHEC
MRDPRAYPKLLGSVRWGKQEDVLATHRLLDRSNAWDTSGLDVGLAMQLLDCHYSDAQVRS
MAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGENMLQDFRKQVEMTEALQKVTREMKAMSADKYDVTQQ
VVIQLRQKLETLQLSGLPESFRVPYDPGLRAGTLLIEQCKVMASKKKPLWLQFKRADPTT
LSKDPVGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIV
KDATTIATIQQSVVGSTGAFKDEILYQWLRDKCVSEEKFQQAVERFLYSCGGYCVATYVL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKS
SPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSED
EAQRHLLDQIEICREKGWMVQIN
>A0A2I2UYM7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Felis catus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A5F8GHU0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodelphis domestica|TrEMBL
MPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISHIKQMLWKQAHSY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKVVTRNCDPGEKLDSKI
GVLIGKGLHEFDALEDPEVMEFRSKMRQFSEEKIQSLIGLSWMDWLKHTYPPEQEPSIPE
NLEDKLYGGNLVVAVHFENCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEVDPYDY
VLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPKLTLVECCNIKKMCEQEMIAIEAAINR
NSSNLPLPLPPKKTRIISVMFFLFNTFSIKLNFHISFQVHVRAGLFHGTELLCKPVVSSE
ISGRNDHVWSEPLEFDINICDLPRMARLCFAVYAVDKVKTKKSTKHYPVAWVNTMVFDFK
GQLKSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIKFPENKKQPYYYPPFD
KVSRGGKKFHVVLKEIMERDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSVKWNKL
EDVAQVTTGSSSIWPKLPPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQ
VLKYEPFLDCALSRFLLDRALANRRIGQFLFWHLRSEVHIPAFSVQFGVILEAYCRGSVG
YMKVLSKQVEALNKLKTLNSLIKLNAMKLNKAKGREAMHTCLKQNAYREALSDLQSPLNP
CVILSELYVEKCKYMDSKMKPLRIVYNNKVFGGDPVGVIFKNGDDLRQDMLTLQMLRLMD
LLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNW
LKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVRKTGQLFHIDFGHILGN
FKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLF
ALMLTAGLPELTSVKDIQYLKDSLALGKSDEEALKQFKQKFDEALRESWTTKVNWMAHTM
RKDYRS
>A0A3Q2UF17|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gallus gallus|TrEMBL
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPIKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQVNSIANPPKMA
VKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNVAS
HPVYYPSFEQLLELGRNGEQPRSAPEDPEEKLQLKEILERRNHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLTITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHV
CMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCEKAYMILRRHGPLFLHLFALMKAAGLPELTCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8I5N6A3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Papio anubis|TrEMBL
MELENYEQPVVLREDNCRRRRRMKPRSVAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVASDFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPAVSSKASAESHSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQN
>A0A7N4P184|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sarcophilus harrisii|TrEMBL
MDLEDHDPVILREDNRGRRRKMKPQSAGMNLSSMEFIPIEFVLPTTHPLTKVAETVILEA
AGNCSVEQVKAQVWMQAVETSMTMEFYHQSSPEQFLLLYQKKEQWYEIYDKYQLIETLDC
VKYWKAFHKNMGQIHVVQRQPPTEETWAFQKQLNDLIDYDVTDMSNVHDDELEFTRRRLV
TPRIMEVASRDPKLYAMHPWITSKPLPTYLLKKIVNNCILIVIHRSTTSQTIKVSADDTP
GTILQSFFTKMAKKKSLMDIPESQNELDFVLRVCGRDEYIVGETPIKNFQWIRHCLKNGE
EIHLVLDTPPDPGQDEVRKEDWPLVDDCTGVTGYHEQLTINGKNHERVFTLSLWDCDRRF
RVKIRGIDIPVLPRNTELTVFVEANIQHGQQVLCQRRTTSKPFTEEVLWNVWLEFDIKIK
DLPKGALLNLQIYCGKAPSQSSKAAGSHEISSFEAKGKTQLLYYVNLLLIDHRYLLRHGE
YVLHMWKISGKGENQGSMNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPE
GDRVRGEMPNQLRKQLEEIIATDPLNPLTAKDKELLWHFRYESLKHPKAYPKLFSSVKWG
QQEIVAKTYQLLARREAWDQSDLDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHY
LLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEA
YLRGCGMAMLEDFTKQVQVIRLLQKVTIEIKSLSAEKYDVTSQVISQLKQKLENLQNSNL
PKSFRVPYDPGLRAGILMIEKCKVMASKKKPLWLEFKCADPTAQSNETIGIIFKHGDDLR
QDMLILQILRIMGSIWEAESLDLCLQPYGCISTGDKIGMIEIVKDAITIAKIQQSTVGNT
GAFKDEVLNHWLKEKCPIEEKFQAAVEKFVYSCAGYCVATFVLGIGDRHNDNIMITETGN
LFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQGILKELLKT
D
>A0A8C3WJB3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Catagonus wagneri|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFILPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PATILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSSKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIETDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDMLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFAQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7J8HUU2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rousettus aegyptiacus|TrEMBL
MPPAMADILDIWAVDSQIASDGSILVDFLLPTGIYIQLEVPREATISSIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRIKMRKLSEEKIQSLVGLSWMDWLKQTYPPEHEPSILE
NLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDEVSPCDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINR
NSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCLAVYAVLDKVKTKKSTKTMNPSKYQ
TIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIVLHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLVELKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQTLRKWSPLTPLSIMRT
AGSLGPWGRQGGGPINEKKWGKLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLR
QMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVHIPAVC
IQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMHTCLKQ
NAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGD
DLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSS
NVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVK
KNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCED
AYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEA
LRESWTTKVNWMAHTVRKDYRS
>A0A8C7E4B3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Naja naja|TrEMBL
MPPAMADILDIWAVDSHIAADSSISVDCLLPTGIYISLDVPRDATISHIKQLLWKQAHSY
PLFHLLLEIDSYMFSCVNQTAVREELEDETRRLCDIRPFLPVLQLITRSCDPGEKLDSKI
GVLIGKGLHEFDALQDPEIKEFRIKMRQISEEKMQSLMGLSTMNWLKHTYPPELEPAIQD
NFQDKLYGGNIVVAIHYENCQDVFSFQVSPNITPIKLNELAIRKWLTIHGKEDEVDPYGY
VLQVNGRLEYVFGDHPLIQFQYINCCVINRALPQLTLIECSTIKTMYEQEMIAIEVAINR
KSNNLPLPLPPKKSRLTQSVWEIVQPFKILLVNGSKLNTEETAKVHIRSGLFHGNELLCK
PIVSSEIAGRNDHVWNEPLEFDINVCDLPRMARLCFVVYAVMDKMKNKKSAKALNPSKYQ
TMRKAGKVHYPVAWVNTMIFDFKGQLKTGDLLLHSWSSFPDELEEMLNPMGTVQTNPYSE
NATTLQIRFQEYSKCPIYYPPFDKILEKAAEIARNSDCSGMAGRGGKKFFIELKEIMERD
PLSQLCENEMDLIWTLRFDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPRE
ALELLDFNYPDQYVREYAVGCLRQMSDEELAQYLLQLVQVLKYEAFLDTALSRFLLEKAL
ANRRIGQMLFWHLRSEMHIPAVSLQFGVILEAYCRGSITHMKVLSKQVEALNKMKTLNSL
IKLNAMKQSKAKGKDTMHTCLKQSAYKEALSHLQSPLNPSVLLSELCIEKCKYMDSKMKP
LWIVYSNKAFGAELVGIIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRLLPYGCLATG
DYSGLIEVVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNTGEDLDRAIEAFTLSC
AGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFI
HVIQQGKTGNTEKFGRFRQCCEEAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKNDDEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A4W5PFU8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
YLLVLVPAMPPAMTDDLDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLL
LWKQAQSYPLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFCPMLKLVTRSCGR
AERLLDSKIGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLTLSAP
RHLFLSSVSLSLSVCVCCVDDNVLSLQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSSVQAMFEKEISA
IGAVVNRKSSNPPLPLPPKRRGPSVSYTLSLSVCVCVCVQVRAGLFHGTELLCKPAVSSE
SSGRSEHVWNRTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKSTKNAHINKYQTIRKAG
KVHYPIAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPIGTIQTNPYTENATALH
IHLPDYNPHPILFPPFDKILEKAAEIAGSSDCSTMVLSGGKKFHIELKEIMERDPLSQLC
ENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLD
FNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLNRAQCNRNIG
HFLFWHLRSEMHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTI
KNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMDSKMKP
LWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATG
DRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKAIEEFTLSC
AGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFI
HVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A7K4SZL6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Burhinus bistriatus|TrEMBL
MELGDDEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKVKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDSPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIVQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C7U995|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MEQQVSDEEEPQPVVLREEIRRRRRKMKAFTSTFSVAVDQIAVEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCVRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELSDRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVYTISLWDC
HRKFRVKILGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNAWLEFN
IRIRDLPKGARLSLQVFCGKAQTQISKGGGGSSSHDGSKTKNRLLYYVNLLLVDHRSLLR
QGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYPVALPKSREGK
AAGGEGREAEGGERGQREMPNHLRKQFEVIVETDPLHPLSQEDKELLWHFREECMRHPRA
YPKLLGSVLWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKL
ETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMH
YQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQVVFQLR
QKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTTLSSDTI
GVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTI
ANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLGVGDRH
NDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFQR
FQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEEAQRHL
LDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A8C7RM72|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHEVFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKCPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGESSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRYYRHTTHMGDSLWLCLSPRWNEWLTYDMYIPDIPRAAR
LCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGV
TGSNPNRETPCLELEFDYFSSPVKFPDMTTVEGHANWTISRELGFSYCQSGQSNRVARDH
ALTDSDNEQLRQVCNRDPLSEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVA
QMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKY
EQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKH
LSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQL
GNIRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIME
NIWQNQGLDLRMLPYGCMSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWL
KDKNKGEMYDLAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHK
KKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINL
FSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHT
IRQHALN
>A0A8C9SXR3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MAPGVYCLPNMWEGGVQQVKMDFLLPTGIYLSFGVSGNDTIGAIKKTLWRNAKNEPLFFA
LSDPDAYVFTCINHTAEQEELEDEQRRLCDVRPMMPILRLVAREGDRVEKLITSQISLLI
GKGVHEFDTMKNHEVNEFRTKMRTFCEELAMDRQRLPWQKWIEYSFPCDLEPCALLSHSG
NLRNRASKKIIVNVKFEESFTLQVEPQEVPLTLMKSALKKKATVFRPMKQEKPEDYALQV
NGRWEFIYGNFPLCQFKYIFNCLHSGVTPHLTMVHYSTITKYQEEQGGISREISKNRSSS
KPPPLPLKKVREQCTDDLGCRIRCLVVQAGLFHGSELLCKVVTSSEVNVCSEPVWDQKLE
FDINVCDLPRMTRLCFALYAVIEKSKKPRSTKKKNKKADCPLSWVNTMVFDYKDQLKTGE
YYLSTWPSVPDDKTDLLNPMGTVEINPNTDSAAGLLIRFQNVRPHPIYYPSLDKINDFMI
NGKKSVATKEEVRLSEIVENKNYTEFFEDDKEILWKLRYEVREKYSESLSKLLLITKWNK
HEDVAQMVSLLQKWPDLPALHALELLDYSFPDRNVRSFTIRCLRKLSDDELFQYLLQLVQ
VLKYESYLDCDLTKFLLERALSNKKIGHFLFWHLRSEMHVPSVNLRFGLILEAYCRGSIY
HMKTLMKQNEALNKMKSLNDFVKSASQKGTRTQTTGEMKKCIKQETFMEALSDLLSPLNP
SLILSEICPDRCKYMDSKMKPLWLVYKNEKVQGDPLGIIFKNGDDLRQDMLTLQMIQLME
ILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNW
LKSKNPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGN
FKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYKILCRNGTLFVNLF
ALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMVHSV
SKDNR
>A0A8C3C2M1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cairina moschata domestica|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDVAVLNRSVLHAHSQLPLKFQ
>A0A8C5PFU7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptobrachium leishanense|TrEMBL
MCRMPPGVYCPVDFWAKEEKQNISVDFLLPNGIYINFRVSCDAYLENIKKLLWQHAQQEP
LFHMLSHPSSYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAEKLLNSQI
SLLIGKGLHEFDSLNDPEVNDFRSKMQQFSEDTALQRQQMSWQSWMETNFPLQLELSSMV
FARESTLNKTLMVNVKFESSEESFTLQVSCRDFPVTLVSLALKKKSNVFGQRSLGHPEDY
TLQVNGVLQYLYGNYPLCQFTYINNCLLQNCTPHLTLVSMSNMLPDKQGDATVPSSKLRQ
KPPPLPSKKPLHISLWNLNNPFSILLIQASNVNGDEGYKLLVHAGLYHGSELLCKTVASS
EVNASSDPVWKQPLEFDIATCDLPRMTRLSLALYAVDKSRRARSARKKSKKADYPIAWVN
TMVFDYKDLLKSGEYSLCMWASFPDDKGELLNPMGTVQCNPNTESAATLRVSFPTYDYPV
YFPSIEKILELGRCSEIPNPTPEEQQQLQEIVERKGHAELYEHEKDLVWKLRHEIKDRHP
DALSKLLLTTKWNRHEDMAQMIHLLQSWPELPVLTALELLDFNFPDHYVGIFTIECLNKL
TNEELCHYLLQLVQVLKYESYLDTELVKFLLQRALIHRKIGHFLFWHLRSEIHVPAVSVR
FGLILEAYCRGSNYHMKVLMKQGEALSKLKGLNDFVRSSMQKTNSKPMAKEAMHVCLKQE
SYREALSNIYSPLDPDMILTDICAEVCTFMESKMKPLWIVYNNDVSGGSRVGIMFKNGDD
LRQDMLTLQMIKLMDLLWKREGLDLRVTPYGCLSTGDKTGLIEVVMHSDTIANIQRNNSN
MAATAAFNKDALLNWLKSKNPGDALEHAIEEFTLSCAGYCIATYVLGIGDRHSDNIMIRE
TGQLFHIDFGHFLGHFKTKFGINRERVPFILTYDFVHVIQRGKQSNSEKFDRFRDCCEKA
YMILRSHGSLFLNLFALMKAAGLPELSCSKDIQYLKDSLALGKSEEDALKHFKVKFNEAL
RESWKTKVNWFAHNVAKDNRQ
>A0A7L1TKM9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phainopepla nitens|TrEMBL
QVLWKHAQYEPLFHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREG
DRAKKVINSQISLLIGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYN
FPLQLEPVAKGPGTGSMHIPTKNIFVNIKFQSGGESFTFQISPREFPITLMSYAVKKQAT
VFRHETVQKPEDYTLQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMR
DEQTNCITSPPKAASKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAG
LFHGTEMLCKTVSSSEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARS
TKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTE
SAAALVICFPSVAAHPVYYPSFEQLLELGRNGEQPRAAAEDSEEKLQLREILERRSHTEL
YEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELL
DFSFPDRYVGSFAINSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKI
GHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSS
QKATKPQTKEMMHMCMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVF
NNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGL
IEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCV
ATYVLGIGDRHSDNIMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQ
GKTNNNEKFERFRGYCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLAL
GKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A835NVV4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lamprotornis superbus|TrEMBL
MELKMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKY
PLYQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNRE
IGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAE
LPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSS
EQLKLCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQ
LPLDTFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYV
RTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAK
EEHCPLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELE
FDWFSNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICT
RDPLSEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPE
QAMELLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKK
ALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLT
DILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAK
RPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPY
GCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDL
FTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVL
TQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSF
DDIAYIRKTLALDKTEQEALEYFMKQMNDAHHEPKERFTFAITLSFV
>A0A822HMG8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ranitomeya imitator|TrEMBL
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLD
CLRYWKMMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIVNNCIFIVIHRGTTSQTIKVSADDT
PDTILQSFFTKMAKKKSLMNIPESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRNEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPSLSSKASVETPGSESKGKAQLLYYVNLLLIDHRFLLRHGGY
VLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGKAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSSLP
ESFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKRADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWEAESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVRAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALMVGRSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7N6BPC3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPGKYGMQGEWEKEGDHEIMMDFLLPTGIFLKFPVSRNDTIKTIKRMVWKNARSEALFT
ALGDPDAYVFTCINHTAEREELEEESRRISDVQPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEVQKNHEVNEFRTKMRVFCEEKAQERQRLPWHQWMEYSFPCDLEPSDTEFEL
CVLMRSALKKKATVFRSVRQEPEDYTLQVNGRWEFIYGNHPLCQFKYIFSCLRNGQNPHL
IMVHHSTISKYQEEQGRMCNQVYKSCSLSRPPPLPLKKVRGQRTVASACVFPLQLVVQAG
LFHGSELLCKVVTSSEVTVCSEPLWDQKLEFDINVADLPRMGRLCFALYAVIEKAKKPRG
TKKKNKKAVITIRSHSTQCHYDCPIAWVNTMVFDYKDQLKTGEFLLTLTQIDLLNPMGTV
ERNPNVDSAAGLLIRFANIRPYPLYYPPLDKVLVLKTLYQSLKCLFVLLCQKQTKSFVKL
KEIMDNKNYTEFFEDEKELLWKLRAEVRSSYPESLSKLLLITKWNKREDVVQMVSLLRNW
PDLPAIHALELLDYSFPDPAVRSFTIRCLRNLSDDELLQYLIQLVQVLKYESYLDCDLTT
FLLERALSNRRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIRLLTKQNEALAK
MKSLSDFVKSGSQKMTVEDLKLCIRQESYLEALSDLLSPLNPSIILSGICADKCRFMDSK
MKPLWLMYKNPGTQGDMVGIIFKNGDDLRQDMLTIQMIQLMENLWKKEGLDLRMIPYGCL
STGNKTGLIEVVKNSDTIANIQRNCSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEVFT
LSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTY
DFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQ
YLKDSLCLGKSDDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A7N6A6N8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPGKYGMQGEWEKEGDHEIMMDFLLPTGIFLKFPVSRNDTIKTIKRMVWKNARSEALFT
ALGDPDAYVFTCINHTAEREELEEESRRISDVQPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEVQKNHEVNEFRTKMRVFCEEKAQERQRLPWHQWMEYSFPCDLEPCCSPQCG
SSRSKNTKKILINIKFEASDESFMLQQDPQDPPLVLMRSALKKKATVFRSVRQEPEDYTL
QVNGRWEFIYGNHPLCQFKYIFSCLRNGQNPHLIMVHHSTISKYQEEQGRMCNQVYKSCS
LSRPPPLPLKKQNTSSLWSINEPFCIHLVQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SSEVTVCSEPLWDQKLEFDINVADLPRMGRLCFALYAVIEKAKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVERNPNVDSAAGLLIRFANIR
PYPLYYPPLDKVLVLKTLYQSLKCLFFVKLKEIMDNKNYTEFFEDEKELLWKLRAEVRSS
YPESLSKLLLITKWNKREDVVQMVSLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLR
NLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVS
LRFGLILEAYCRGNIHHIRLLTKQNEALAKMKSLSDFVKSGSQKMTVEDLKLCIRQESYL
EALSDLLSPLNPSIILSGICADKCRFMDSKMKPLWLMYKNPGTQGDMVGIIFKNGDDLRQ
DMLTIQMIQLMENLWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNCSNSAA
TAAFNKDALLNWLKSKNPGDKLDQAIEVFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQ
LFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKI
LCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLCLGKSDDEALKNFKVKFNEALRES
WKTKVNWMMHSLAKDNRP
>A0A7K7CIK5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aphelocoma coerulescens|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPAKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K8HD49|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aleadryas rufinucha|TrEMBL
TACAAPQVLWKHAQYEPLFHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLR
LVAREGDRVKKVINSQISLLIGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWA
AWMEYNFPLQLEPVAKGLGTGSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYA
IKKQATVFRHETVQKPEDYTLQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSS
AIIAMRDEQTNCITSPPKAASKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMK
LVVQAGLFHGSEMLCKTVSSSEVSVCSEPVWKQRLDFDISVCDLPRMARLCFALYAVIEK
AKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQ
CNPNTESAAALVICFPSVAAHPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILER
RSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVL
NALELLDFSFPDRYVGSFAINSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERA
LSNRKIGHFLFWHLRSEMHVPAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALND
FVKVSSQKATKPQTKEMMHMCMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMK
PLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLST
GDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDF
VHVIQQGKTNNNEKCVRFRGYCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYL
KDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C7AGV0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neovison vison|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKXXXXXXXXXXXXXXXXXXXXXXXCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPSRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGKHEYLYGSYPLCQFQYICSCLHSGQTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFEYKDQLKTGECRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCLR
QETYLEALSHLQSPLDPSTRLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7K6R527|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Climacteris rufus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVLWQQAQQEPLFH
MLSDPEAYVFTCINQAAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGT
GSLQTHTKNIFVNVKFQSGGESFTFQISPREFPITLMSYAIKKQATVFRHETMQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKTV
TKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
ANVMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALLICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAGPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQHPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMRVLMKQGEALNKMKALNDIVKASSQKAPKPQTKELMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A672RPH6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDATGSHSRALYVYPPNVESSSELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEVMI
CFFVVFFSSDLQNSRLARDHAMTEADIEQLRQLGNRDPLSEITEQEKDFLWRHRQYCVNI
PEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEK
YLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVS
QRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRR
PDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIF
KNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQ
CKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAIDLFTRSCAGYCVATFILGIGDRHNSNI
MVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERC
ECFNIVSYENHLKSPEICKNFIVFTVH
>A0A8C9NVV7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Serinus canaria|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPATMGLSS
LQIPTKNIFVNVRFQSGGESFTFQISPWEFPITLMSCAIKKQATVFRHETVQKPEDYTLQ
VNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGAEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q3M798|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDSVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYSQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKVGMPATD
PQLQWNEWLTYDMYISDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVA
NKMALNLWPVPHGLEDLLNPIGITGSNPNKETPCLELEFDHFSSPVKYPDMNAIEDHANW
TISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPLSEITEQEKDFLWRHRHYC
MNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAMELLDCNYPDPMVRHFAVRC
LEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSEMHNK
TVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMRFLVDQ
MKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMSELLFQNNE
IIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRSSHTIM
QIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDMAVDLFTRSCAGYCVATFILGIGDRHN
SNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECTKTKEFE
RFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKSEQEALDY
FMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8D1WA96|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKEHCPLAW
GNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVV
KFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPLSEIT
EQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDC
NYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIG
HFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKK
DETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWE
NPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDC
VGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGY
CVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVI
SKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRK
TLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3Q2WCS4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Haplochromis burtoni|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGHPAALRHVREREHQRHR
>L8I810|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASMSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIIKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIK
QGEKHSA
>A0A8I3PQH2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MEPQGCEPRVVLREDHRRRRRRMKARGPAAGLPSMELIPIEFVLPTSQRSSKAPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYQRLGPDHFVLLYQKKGQWYEIYDRYQVVQTLD
CLRYWQLLHRSPGQIHVVQRRAPSAATLAFQRQLTALIGYDVTDLSNVHDNELEFTRRRL
VTPRMLEVAGRDPELYAMHPWVTSKPLPDYLRKRIPNNCVFIVIHRGTTSQTVKVSADDT
PGAILRSFFAKMAKKKALMGIPEGQSERDFVLRVCGRDEYLVGDTPLQNFQWVRQCLKNG
EEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRR
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFSIKI
KDLPRGALLNLQVYCSKAPTLSAKASADAPGAGSEARGKAQLLYYVNLLLIDHRFLLRRG
EYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDP
EGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKW
GQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLH
YLLQLVQNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLEAYLRGCGTAMLHDFTQQVQVIE
MLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLPESFRVPYDPGLKAGALVIEK
CKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESL
DLYLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCAIEEK
FQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINK
ERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMP
QLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKH
SA
>A0A2I2ZMF3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gorilla gorilla gorilla|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGSSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7K5K6H9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mionectes macconnelli|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIMHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPNPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDTKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMDIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C4NX37|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MPPGKYGMQEEWEKEGDQGILMDFLLPTGIFLKFPVSRNDTIKSIKKMVWRNARSEALFS
GLGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPMS
GSMKSKSTKKIFINVKFEACDESFMLQQDPQDFPVALMRSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGKHPLCQFKYIFSCLRNGQNPHLTMVDHTTISKYQEEQGRMCSQVYKSR
SLSRPPPLPLKKQNTSSLWSINEPFYINLVQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSPEVAVSSEPLWDQNLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFHNI
RPHPLYYPPLDKISDVEKNGDAGIPTKEEYMKLKEIMDNKNYTEFFEDEKELLWKLRTEV
RNHYPESLSKLLLITKWNKREDVVQMVSLLRKWPDLPAIHALELLDYSFPDPAVRSFTIR
CLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLRSEIHVA
SVSLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKSGSQKMTVDDLKLCIRQE
SYLEALSDLLSPLNPSIVLSEICADKCRFMDSKMKPLWLLYKNPQAQGDMVGIIFKNGDD
LRQDMLTLQMIQLMENLWKKEGLDLRMIPYACLSTGNKMGLIEVVKNSDTIANIQRNSSN
SAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERA
YKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A667H169|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lynx canadensis|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLLERPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSAPDEKGELLNPAGTVRSNPNTESAAALVICLPEVSP
YPVYYPALDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPDLPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMRQGEALSKLKALNDFVKVSSQKTTRPQTKELMHLCMR
QETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDSSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGPLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A674AEM2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
FLSDEEEPQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTLLLE
VAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQTLD
CIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKL
LTPRKIELADRDPKLYSMDPWITSKHLPEYLLTNFHYLFPEDVCEGDYILRVCGREEYIY
GNHPVRDFHWVRQCLKNGEEIHLVLESAPNPGQDLVQKEDWAQVDDCTGVAGTHEQLTID
EKDHERVFTISLWDCHRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSK
AFTEEVLWNTWLEFNIRIRDLPKGARLSLQVSCGKAQTQISKGTSSYQDNGGSPTKSRLL
YYVNLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLD
KYCYPVALPKSREGKEAGGEGREAEGGERGQREMPNHLRKQFESIVETDPLHPLSQEDKE
LLWHFREECMRHPRAYPKLLGSVRWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDC
HYSDAHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGH
FLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMS
AEKYDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVVKQCKVMASKKRPLWL
QFKRADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTG
NKIGMIEIVRDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCG
GYCVATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLY
VMGTSGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIRE
ALTVGRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGGDKRSA
>A0A674D5M6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MEQQVSDEEPQPVVLREEIRRRRRKMKAFTSTFSVAMDQIAIEFILPTTTKSSRSPDTLL
LEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSSDHCILLYQKKGNWCEIYDKHQVFQT
LDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRKNELSDRDPKLYSMDPWITSKHLPEYLFTKVTNSHILLVIHRNKASQTIKVSID
DTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCLK
NGEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDCH
RKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFNI
RIRDLPKGARLSLQVSCGKAQTQISKGGGGSGSHDGSKTKSRLLYYVNLLLVDHRSLLRQ
GEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAIAILLDKYCYPVALPKSREGKV
AGGEGREAEGGERGQREMPNHLRKQFEAIVETDPLHPLSQEDKELLWHFREECMRHPRAY
PKLLGSVLWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLE
TLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHY
QQRYAVLLEAYLRGCGEDMLQDFRRQVEITEALQKVTREIKAMSAEKYDVSAQVVFQLRQ
KLENLQTSGLPESFRVPYDPGLRAGALVVKQCKVMASKKRPLWLQFKRADPTTLSSDTIG
VIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTIA
NIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLGVGDRHN
DNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFQKF
QDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEEAQRHLL
DQIEICRDKGWTVQFNWFLHLVLGIKQGGDKRSA
>A0A674AHA1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MEQQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKGAALWATLCCLPAPSLFSIGHILLVIHRNKAS
QTIKVSIDDTPVQVLQTFFTKISNKRALLGVPEDVCEGDYILRVCGREEYIYGNHPVRDF
HWVRQCLKNGEEIHLVLESAPNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVF
TISLWDCHRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLW
NTWLEFNIRIRDLPKGARLSLQVSCGKAQTQISKGGSSSHDGNKTKSRLLYYVNLLLVDH
RSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYPVALPK
SREGKEAGGEGREAEGGERGQREMPNHLRKQFESIVETDPLHPLSQEDKELLWHFREECM
RHPRAYPKLLGSVRWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSM
AVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEI
AQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQV
VFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTTL
SSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVR
DATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLG
VGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSS
PHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEE
AQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGGDKRSA
>A0A7K7F1E6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chionis minor|TrEMBL
MELGDDEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEISQTTEFYNMFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKIINNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLNDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLTAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSVHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>K9IPS7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Desmodus rotundus|TrEMBL
MCFNSIMPPAMADILDIWAVDSQIPSDGPIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQIHNYPMFSLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWIDWLKQTYPPEH
EPSNLENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQISGRLEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNFPLPLPPKKTRIISHVWENNSPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NASKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSIQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEDEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A099ZH71|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tinamus guttatus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSGNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHVFSPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNS
EEIHLVLDNPPDPREDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIVGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIRI
KDLPKGALLNLQIYCGKAQGLSTKTHESPNSDSKCKTQLLYYVNLLLIDHRFLLRSGEYV
LHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSDLPGD
RTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQ
EIVAKTYQLLAKKEVWDQSALDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVLHYLL
QLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYL
RGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIMQLRQKLEKLQSSNLPE
SFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQD
MLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTGA
FKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITEAGNLF
HIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSVHFHKFQDVCVKAYLALR
HHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDKGWT
VQFNWFLHLVLGIKQGVEKHSA
>A0A6J3GRT0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sapajus apella|TrEMBL
MCFGFIMPPAMADILDIWAVDSQIASDGTIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDGLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
ISPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIIYHVWENNNPFQIILVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEVSGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKAKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIMLHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6I9Q2D7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Notothenia coriiceps|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAIDLRDCNGPHSRALYVYPPNVESSVELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKEKMEIANIEPKQSIPLSRKGLRGTLSAAE
RD
>A0A671G5P7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinolophus ferrumequinum|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRLPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFESSLSPWQHLQTKESEGNVFRMFQEPACTGKH
>A0A7K8KT41|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ardeotis kori|TrEMBL
MELGDCEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTEFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQALSTKTNLQAHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKDVWDQSTLDVGLTLQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L0AKM9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ciconia maguari|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQMSPKEFPITLISYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLMPHLTMVHSSTIIAMRDEQTNCIASPPKTA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A643CDQ6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balaenoptera physalus|TrEMBL
MPPRPSSGELWGIHLMPRLLVECLLPNGMIVTSECLREATLITIKHELFKEVRKYPRHQL
LQDESPYIFVLPKKQKGEEFFHETRRLCDLKLFQPFLKATMKKRSSTEKLVLPDLNSPHG
GAMYVYHPNVESSRELPKRIHNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHNCVPEQVI
AEAIRKKIQSMLLSSEQLKLCILEYQGKMPSLMLMAKERLYSQLPMDCFTMPSYSRCIST
ATPYTNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNT
LVNTRVPCSSPRWNEWLNYDIYIPDLPHAARLCLSICSVKGRKGAKEEHCPLAWGNINLI
TQMNSIPHGLEDLLNSIGVTGSNPNKETPCLELEFDWFRQCGEVSRYQFVHEILYLKSLS
KRFSVEPQTLFYPDLMVRGFAVQCLEKYLTDDKLPQYLIPLVQVLKYEQYLDNLLVRFLL
KKALTNQRIRHFFFWHLKSEMHNKTEVWPAFGVLLLCIYGKSSLTDILKQEKDETRKVQM
KFLVEQMRLLDFMDALQGFLLPLNPAHQLGNLKLEQCRIMSSAKRPLWLNWENPDITSTA
THYVSGSKTRTREKYDAAINLFTCSCAGYCVATFILGIGDGHNSNIMVKDDGQLFHIDFG
HFLDHKKKNFGYKRERVPFVLTQDFLIVISKGAQECTDKXGHFLDHKKKNFGYKREHVPF
VLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQ
SFHDTAYI
>A0A4U5V1M1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Collichthys lucidus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSTDLPKH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHEYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMTIIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDTDTEQLRQVCNRDPL
SEITEQEKDFVWRHRQDCVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A674MGB1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
MPPGKYGMQEEWEKEGDQRIVMDFLLPTGIFLKFPVSRNDTIRTIKKMVWKNAQSEALYA
ALGDPDSYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVARVGDRVEKLTNTQISQL
TGKGLHEFEAQKNHEVDEFRAKMRTFCEEKAQERQVLPWLQWMECNFPCELEPCSSPVEC
GGVKSKNTKIFINVKFEASDESFMLQQDPQDLPAALMRAALKKKATVFRSVRQEPEDYTL
QVNGRWEYIYGRHPLSQFKYIFSCLRNSQNPHLTMVHHSTIRKYQEEQGRACSQAYKCHR
PSRPPPLPLKKQNTSSLWSINEPFHIRLLHGSRVNAAEGMKLVVQAGLFHGSELLCKMVT
STEVAVCSEPVWDQKLEFDINFSDLPRMSRLCFALYAVIEKNKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIQFPNVR
PHPLYYPPLEKVPVPAQVRRLRKTKEIMDNKNYTEIFEDEKELLWKLRSVVCDHYPESLS
KLLLITKWNKREDVVQMVGLLRYWSDLPAIHALELLDYSFPDPAVRAFTIRCLRKLSDEE
LLQYLIQLVQVLKYESYLDCDLTTFLLERALSNSRIGHFLFWHLKSEIHVPSVSLRFSLI
LEAYCRGNIWHIKLLIKQNEALLKMKTLSDIVKSGSQKMTVDDLKLCIKQESYLETLSDL
LSPLNPSVVLAEICADKCRFMDSKMKPLWLMYKSPWAQGDMMGIIFKNGDDLRQDMLTLQ
MIRLMEILWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNK
DALLNWLKSKNPEGKLEKAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDF
GHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGM
LFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVN
WMMHSLAKDNRP
>A0A5N3XMM6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Muntiacus reevesi|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A452IDY8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gopherus agassizii|TrEMBL
MELGNYEQPVVMREEAKRRRRRMKPHSPASNLSSVELISIEFILPTSNKQVQETMLLEIA
GNCTVEQMKAQIWMRAIEMSQTTDFYHKFPPDQFILQYQKKGQWYEIYDKHQVIQTLDCI
LYWKVLEKKVGKISVIQKQKPAQAVQEFQTQLNDLIGYDVTDVSNVHDDELEFTRRRLVT
PRMIEVACRDPKLYSMHPWITSKPLPEYVLKKITNNNIFIIIHRGTTSQKIKVSIDDTPD
MILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNGEE
IHLVLDDPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRKFR
VKIVGIDIPVLPRNTELTVFVEANIQHGQQLLSQRRTISKPFTEEVLWNTWVEFDIKIKD
LPKGALLNLQIYCGKAQALSTKVNLQSHDSPNSDSKCKTQLLYYVNILLIDHRSLLRSGE
YVLHMWKISGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSDPQ
GDRTRAEMPNQLRKQLEAIIDTDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWG
QQEIVAKTYQLLAKREAWDHSSLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVLHY
LLQLVQAVKFEPYHDSALARFLLKRGLRVSTSKLNNIK
>A0A8D0HNY0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphenodon punctatus|TrEMBL
MPPGIYCPVEFWSNEENQNIQVDFLLPTGIYLSLPISCNASLGTIKQVLWHHAQQEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMRQFCEEKAAKRQQLSWAAWMQYNFPLQLEPSSKGLRS
GSLHVPNKNIFVNVKFESGGESFTFQISPKEYPIMLMSYAIKKQATVFRHQTVESPEDYT
LQVNGKCEYLYGDYPLFQFQYIRSCLHLGLMPHLTMVHSSSILAMRDEQTNCIAHPPKVA
PKPPPIPKKKLTTATLWSLEQPYYIHLVQGSKVNADERMKLVVQAGLYHGNEMLCKMVSS
SEVNMCSEPVWKQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKGGESCLHMWSSFPDEKGELLNPMGTVRSNPNTESAAALVICFPSVTS
YPVYYPSFEHLMELGRSGDYARPMAEDPEEKQQLKEILERRTHTELYEHEKDLVWKMRYQ
ICDQYPEALAKLLIITKWNKHEDVAQMIHLLQCWPELPVLSALELLDFSFPERYVGSFTI
NSLKKLTSEMHVPAVALRFGLILEAYCRGSNHHMKVLMKQGEALNKMKALNDIIKASSLK
NPKPQTKEFMHTCMRQETYLEALSNLQSPLNPSIILAKVCVDQCTFMDSKMKPLWIVFDN
DESGGTGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIE
VVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGAALEQAIEEFTLSCAGYCVAT
YVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGK
TNNSEKFERFRGYCERAYMILRRHGLLYLHLFSLMRAAGLPELSCSKDIQYLKDSLALGK
TDEEARKHFQLKFNEALRESWKTKVNWLAHNVSKDNRQNSLDI
>A0A8C3QEU3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyanoderma ruficeps|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C4ZJZ6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
VSLSLPLSLSLCLCLSLGLCLCLPASLCLSSHMFECVNQAAVHEELEDETRRLCDVRPFL
PVLRLVTRNCGRAERLLDSKIGVLIGKGLHELDALQAQEVKDFRAKMLRVSEARMQFYHA
MTWSEWLQACFSPHALFETTPGSFLNNQDIASLISPGNPFLNPFQSAEETSLRVSPAFTP
TEVMEQGLKKWLTTHGPEDDSRQGPYVLRVSQRLEFLCGDHPLIQYKYIKECIQAREPPH
LTLVLTSTIRTMFEKEISAIGAVVSRKSSNPPVPLPPKRRAPTVSLCVQVRAGLFHGTEL
LCKPAVSSESSGRSEHAWSDGTLEFDIVASDLPRMTRLCFAVYAIMDKVKKQKSTKNTHS
NKKPCPPPAWVNTMVFDYKGQLKTGDVILHSWSSFPDELEEMLNPIGTIQTNPYTENATE
LHVHFQEYSSQPIVFPPFDKVQGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRHDC
HLKFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPRLSPRDALELLDFNYPDQYVREYAVR
CLREMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLERAQANRKIGHFLFWHLRSEIHMP
AVSIQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKTARSKTKEAMLTK
EAMMTCLRQSGYSETLSDLNSPLNPSIQLSGINVERCRYMDSKMKPLWIVYHNKLLRGDS
LGIIFKNGDDLRQDMLTLQILRLMDLLWKENSLDLRIVPYGCLATGDRAGLIEVVSSADT
IANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALDRAIEEFTLSCAGYCVATYVLGIGD
RHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKF
GSFRQYCEDAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALK
QFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C1L367|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGSHSRALYVYPPNVESSSELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLSRLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTEADIEQLRQLSNRDPL
SEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNTLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSTTLHQWLKDKNRGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERCVCACWKHYQLFSSVSLTEIIFCVSTLT
>A0A8C2AT88|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNDLGMNGEKTTKEEHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQRY
PESLPKLLLITKWNKHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRK
LSDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSL
RFGLILEAYCRGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQD
TYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQ
DMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAA
TAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMISETGQ
LFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKI
LCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRES
WKTKVNWMMHTFAKDNR
>A0A8C2GL84|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVAQS
GKSLLIFPSCAETFVLQQDPQDLPMLLKRNALRKKSTVFRAAKQEKPEDYTLQVNGRWEF
IYGEYPLCQFKVSLKFTTSSRLHSYSTTLSDSRTHVFLNLILLFCYFFYQNTSSLWSIHE
PFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSNEVSVCSEPVWDQKLVFDIGV
SDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFSLSTW
PSVPGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKVRYYKRRGKKSNVLI
VDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVGLLRKWPEL
PAIHALELLDYSFPDPHVRSFTIRCLRNLRDDELFQYLLQLVQVLKYESYLDCDLTCFLL
KRALANKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKA
LNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCTDKCKFMDS
KMKPLWLMYKNKYDHVGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLST
GNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDF
VHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYL
KDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A669QWV6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phasianus colchicus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQVSLLSCFDKRKSPNYGSLWSLEQSFYIELVQGSKVNADER
MKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVI
EKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGT
VQCNPNTESAAALLICFPNVASHPVYYPSFEQHFSLYPSLTASLWAERGLWLRLSPLYAL
CCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRHDIRDQYPQALAKLLTITKWNKHED
VAFPPHKGSALPASWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQYLLQLV
QVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGST
HHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQETYLEALSHLQSPLN
PSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLM
DILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALLN
WLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLG
NFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYMILRRHGPLFLHL
FALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHN
VSKDNRQ
>A0A3P8U627|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amphiprion percula|TrEMBL
MPPGKYGMQEEWEKEDQQITMDFLLPTGIFLKFPVSRNDTIKSIKKMVWKNARSEALYSA
LGDPDGYVFTCINQTAEREELEEESRRLSDVRPFMCVLKLVAREGDRVEKLTNTQISQLI
GKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERESLPWQQWMEFSFPCELEPCCAPPESS
SVKPKNSKKIFIQIKFESCQESFMLQQDPQDLPVALMKSALKKKATVFRSVRQEPEDYTL
QVNGRWEFIYGKHPLCQFKYIFSCLRNGQNPHLTMIHHSTIVKYQEEQSKVCSQVSKSGS
LSRPPPLPLKKNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTT
SEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNIDSAAGLLIRFPNIRP
HPLYYPPLDKVLTPPKYILNPPMVSLLRHWPDLPAISALELLDYSFPDPAVRSFTIRCLK
KLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVS
LRFGLILEAYCRGDIHHIKLLTKQNEALGKMKALSDIVKSGSQKMTVDDLKLCIRQESYL
DALSDLYSPLNPSIFLADICVEKCRFMDSKMKPLWLMYLNPSLQGDMMGIIFKNGDDLRQ
DMLTLQMIQLMENLWKTEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAA
TAAFNKDALLNWLKSKNPERA
>A0A8C6PMY5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius furzeri|TrEMBL
MPPGKYGMQEEWEKEGDQNILMDFLLPTGIFLKFPVPRNDTIKNIKKMVWRNAKTEALYC
GLGDPEGYVFTCINDTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNSHISSL
IGKGLHEFEAQKNHEVDEFRSKMRTFCEEKALERHNLPWQQWMEYSFPCDLEPCCSPPVH
GGTKSKHTKKLFINVKFEACDESFMLQQDPLDIPVALMKSALKKRATVFRSVRQEPEDYT
LQVSGRWEFIYGNHPLRQFKYIFSCLRNGQNPQLIMVHHSTISKYQEEQGQLCSQVGKIR
SQSRPPPLPMKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQKLDFDINVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKRADCPI
AWVNTMVFDYKDQLKTGEFILSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPPLDKMIVMERNGDAVFATKVERMRLKEIMDNKNSTEFFEDEKELLWKLRTEV
RDCYPESLSKLLLITKWSKREDVVQMVSLLRNWPDLPAIQALELLDYSFPDPAVRSFTIR
CLRKLSDNELLQYLIQLVQVLKYESYLDCDLTTFLLERLTAEETSTTSSCQKMTVEDLKL
CIRQESYMEALSNLMSPLNPSIILVELCADKCRFMDSKMKPLWMMYKNPSEHADMVGIIF
KNGDDLRQDMLTLQMIHLMEDLWKKEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDR
HNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFE
RFREYCEWAYKILCKNGTLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEDEALKN
FKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A670J955|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podarcis muralis|TrEMBL
MVWHHAQFEPLFHMLSGPESYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGD
RAKKLINSQISLLIGKGLHEFDALSDPEVNDFRTKMHQFCEERVTRRQQLSWKAWMEYSF
PVQLEPSSSSLGRKTASCVLLIIFPSLQESFTFQISPKEFPVTLMSYAVKKQATIFRHQR
MNSPEEYALQVNGKCEYLYGNYPLYQFQVCAPLAYLSAHGLSAWRTHAQSCEVGWLCSPL
SFISLSQLVVQAGLYHGHEMLCKMVSSSEVNVCSEPVWGQRLEFEINVCDLPRMARLCLA
LYAVVEKAKKARSTKKKSKKADCPIAWVNIMLFDYQDQLKTGECCLPMWSSFPDEKGELL
NPTGTVRTNPNTESAAALVIRFPGILLYPVYYPSFEQVRRWWFAPLSLASLVSTSSRKQQ
LKEILERRSHTELYEHEKDLVWKMRHQVRDQYPGALAKLLVVTKWNKHEDVAQMIHLLQS
WPELPVLNALELLDFNFPDRYVGSFTVNSLKKLTDAELFQYLLQLVQVLKYESYLDCKLT
TFLLDRALSNRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKSLMRQSEALN
KMKALNGIVKLSALKNPKPQTKEFMHTCLRQETYLEALSNLQSPLNPSVILAKVSVELCT
FMDSKMKPLWIVFNNEEIGGTSNVGIIFKNGDDLRQDMLTLQMIQLMDILWKKEGLDLRM
TPYGCLSTGDKTGLIEVVMDSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALDR
AIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERV
PFILTYDFVHVIQQGKTSNSEKFERFREYCERAYMILRCHGLLFLHLFALMKAAGLPELS
CSKDIQYLKDSLALGKTDEEARKHFQLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A670J8G1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podarcis muralis|TrEMBL
MELVSSEQPVVMRDDNKRRRRRMKPHSTASNLSSTELISIEFILPTSNMLIDIASNCTVE
QMKAQVWMRAIERNQTSDFYHKFTPDQFVLQYQKKGQWYEIYDKHQIIQTLDCILYWKVL
QKKVGKIHVIQKQKPTEDVQKFQKQLNYLIGYDVTDVSNVHDDELEFARRRLVTPRTIEV
TCRDPKLYSMHPWITSKPLPDYLLSKIVNNNILINIHRGTTSQKIKVPIEDSPDLILQSF
FTKMAKKKSLMNIPEDYSELNFVLRVSGRDEYIVGDTPLKNFHWIRQCLKNEDEIHLVLD
EPPDPNQDEVQKEEWPLVDDCTGVSGYHEQLTIDGKDHERVFTISLWDCNRKFRVKIIGI
DIPVLPRNTDLTVFVEANIQHGQQLLSQRRTTAKPFTEEVLWNTWLEFDIKIKDLPKGAL
LTLQVYCGKAPASSAKANLHLHDSPSSDAKCKTQLLYYVNILLIDHRSLLRTGDYVLHMW
KFPGKGEEQGSINADKLTSATNPDKDNSMAVSIVLDKYCHPIALPKHKVASDPQADRARA
EMPNQLRKQLEEIIATDLLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQEIVA
ETYQLLSKRDAWDQSSLDVGLTMQLLDCNFSDENVRAMAVQKLEGLEDDDVLHYLLQLVQ
AVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCG
KAMLQDFMKQVQVTKLLHKVTMDMKSVSAEKHDVTPQVIAQLKQKLEKLQDSKFPECFRV
PYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTSLSNETIGIIFKHGDDLRQDMLIL
QILRIMESIWEEESLDLCLLPYGCISTGNKIGIIEIVKDATTIAKIQQSTGGNTGAFKDE
VLNQWLKDKCVIEEKFQAAVDRFVYSCAGYCVATFVLGIGDRHNDNIMITESGNLFHIDF
GHILGNYKSFLGINKERVPFVLTPDFLFVMGTTGKKMSPRFQNFQDICVRAYLALRHHTN
LLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEICRDKGWTVQFN
WFLHLVLGIKQGVEKHSA
>A0A8B8TC13|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Camelus ferus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K6EUR8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Grantiella picta|TrEMBL
MPPGIYCPTEFWAKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKICQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GPLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGRTPHLTMVHSSAIIAMRDEQTNCIASPPKVA
CKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKQQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDTLDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K8E3D4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leucopsar rothschildi|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRSKMCQFCEDKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGT
GSLQIPNKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIRKQATVFRHETLQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAILAMRDEQNNCITSPPKAA
CKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWRQRLEFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K9WTB0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhipidura dahli|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELVSIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNVWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQADRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L3GRJ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anhinga rufa|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHAPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAVPEDPDEKLQLKEILERRSYTELYEHEKDLVWKMRCD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEERGGGGVGIIF
KNGD
>A0A7K8EPB1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leucopsar rothschildi|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQA
HSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDVSNPFKIILLKGNRLNTEENAKVHVRAGLFHGTE
LLCKTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTRAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGHLRSGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7L0P3R9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mesembrinibis cayennensis|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMLLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQSDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8D0D4M9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLLSIKQQLFTEARKYPLYH
LLQEESSYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNLESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPARSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLAYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDGEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMLKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFERFQEMCYKVYLSVCLPVSQVPGDVL
>A0A8D2HRB4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Urocitellus parryii|TrEMBL
MELENCEQPVILREDNLRRRRRMKPRSVAASLSSMELIPIEFVLPTSQRDTKIPETALLH
VAGHGNVEQMKAQVWLRSMETSVAADFYHRLGPDHFILLYQKKGQWYEIYDKYQVVQTLD
CLRYWKMLNKSPGQIHVVQRHAPSEETLAFQQQLTALIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVASRDARLYAMHPWVTSKPLPEYLSKKITNNCIFIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDRPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIFCGKAPALSGKASAETPSSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLQDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLETLQNSNLP
KSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7J7F3C8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Diceros bicornis minor|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKVRWNEWL
NYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTATLVSGKMALNLWP
VPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFS
YSHAGLSNRLARDNELRENDKEQLRAICTRDPLSEITEQEKDFLWSHRHYCVTIPEILPK
LLLSVKWNSRDEVAQMYCLAMELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQV
LKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMY
LKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPA
HQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIR
IMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLH
QWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFL
DHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLF
INLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWI
FHTIKQHALN
>A0A7L1R096|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cisticola juncidis|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSPMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFTLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>B0EMX9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Entamoeba dispar (strain ATCC PRA-260 / SAW760)|TrEMBL
MKKSVHSSVVNSQSQGSIVHVFIRHEGEIHSFTYSSTVSPLDIIDSIKSTLHLTGVYSVV
VPNIPFKIVDSMEGSEVKETGFYKSCIEYGIIPAFELVERSQAEKYESVGTLAKLMNQLK
ENYRIIGQTYVDVLSTDAEEIFVFRRSLARTRVLSSKIEAKYDSNLKEENEFAYTLSEPN
IPDTIKSIDVEIIGEDYKTTAVFTITPQVFVHRVIDSAFHELKKAGEDAVKGNEPTEYIL
KVVGWDEYIVPQRVNGKNWLLSDFDYIRRCALHGEPIHLELVKKSRLFSCKINDEERRVL
NYLDSFFASELWEAFDDEKRVSQRLCTDQLSAQVVSVENLYSYIKTKKGEEEEQQMVTDF
LCYFKVELYYGEKPLCPALYSTVFEVKNGLASPKWKFTFIQLIATLPAETKMIYSVYMTN
SIVNTQIEKIGENDKCLGTVNTKIVNYTNDLLNGEQQYYLWASEPNPIAMCCNAVSSKMK
VVVEFPSLTKPIRMDTYITKKKEMQVELEQESGKKMTVEELDAFKKIVDADAMAVFTQEE
LKCLWERRHSLLKTNPHALARLLNSVNYCQPTEVHELHRLLSKWPLLDPQEAIELLDFRY
PDPQIRGFALRCIDTMTDDQLVMYLPQLVQALKFELHHHSTLASFLLERSLKNRRRIGHN
LFWFLKAEIHDARVTGRYGVLMEAFLNGCGKYKNELEKEVTFQNELVVIANEVKQLGTKD
EQKAHLKSSLAKLEYPDEMSLPLDARFRFKKPVPNTGNVFSSKKKPLMLVLENADPLGEP
IMVIQKVGDDLRQDILTLQMIRLMNAIWKNNGLDLCMLPYLCIATGNEIGMLELVKNSET
YGAIMAMDKSKFSVIKDTAVTTWIKEQCARPESPVTFQEAVENFTYSCAGYCVATYILGI
GDRHSDNVMITRDGKFFHIDFGHFLGNFKSKFGVKRERTPFKFTQHFANVLGGKGAPQFV
KFEEICMNAFIIIRKHGPLFIYLFRLMLATGIPELQSAKDIEYMRNMFMFDKNDDEAKEA
FRQLIYKCLDAWSQTVNDLIHDFVHYK
>A0A3B4CZ36|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pygocentrus nattereri|TrEMBL
MPPGVYYGMQDVWEKEGREQVNMEFLLPTGIYLSFPVARSDTIGAIKKMVWKHARSEPLF
NVLSDPDAYVFTCINRTAEREELEDEQRRLCDVQPFMPVLRLVAREGDRVEKLINTQISL
LLGKGLHEFDAQKNHEVAEFRTKMRSFCEEKAQDRQRLPWHQWMEYNFPCDLEPFSRAAQ
SGKSRSVKKIFINVKFEASEESFMLQLDPQDMPVVLMRSALKKKATVFRPVKQEKPEDYT
LQVNGRWEFIYGKNPLCQFKYIFSCLYGGQTPHLTMVHHSTITKYQEEQGTLSSQVSKSR
SLSKPPPLPLKKQNTTSLWSIHEPFYIHLLQGSRVNADESMKLVVQAGLFHGSELLCKVV
TSSEVSVCSDPVWDQKLAFEINLCDLPRMSRLCFALYGVLEKTKKQRSTKKKKKADCPLA
WVNTMVFDYKDQLKTGEFLLSTWPSAPDDKGDLLNPMGTVERNPNIDSTAGLLIRFSNFR
PHPLCYPPLEKLNEAERNGEKISASKEEMVCLLRKWPDLPALHALELLDYSFPDPHVRSF
TIRCLRKLRDDELFQYLLQLVQVLKYESYLDCDLTTFLLERALSNKKIGHFLYWHLRSEM
HVSSVSLRFGLILEAYCRGSIYHIKSLMKQNEALNKMKALNDFVKSGSQKSTSRSQITED
MKLCIKQDTYVEALSDTVSPLNPNIILSDICTEKCKFMDSKMKPLWLMYKNKWVQADTVG
IIFKNGDDLRQDMLTLQMIQLMDILWKTEGLDLRMIPYGCLSTGNKTGVIEVVKSSDTIA
NIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMIRENGQLFHIDFGHFLGNFKAKFGINRERVPFILTYDFVHVIQQGRTNNSEKFER
FRECCEQAYKILCRNGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKNF
KVKFNEALRESWKTKVNWMVHTFAKDNR
>A0A6J0AC77|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vicugna pacos|TrEMBL
MLPKFGPISFQVAQGMELENYEPPVVLREDNCRRRRRMKQRSTAASLSSMELIPIEFVLP
TSQRNTKTPETALLHVAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQ
WYEIYDKYQVVQTLDCLRYWKVLHRSPGQIHLVQRSTPSEETLAFQRQLNALIGYDVTDV
SNVHDDELEFTRRRLVTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIH
RSTTSQTIKVSADDTPGTILHSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGET
PIKNFQWVRQCLKNGEEIHLVLDTPPNPDLDQVRKEEWPLVDDCTGVTGYHEQLTIHGKD
HESVFTVSLWDCDRKFRVKIRGIDIPVLPRNADLTVYVEANIQYGQQVLCQRRTSPKPFT
EEVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSGKASAETPSPESKGKAQLLYYVN
LLLIDHRFLLRHGEYVLHMWQLSGKGEDHGSFNADKLTSATNPDKENSMSISILLDNYCH
PIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKD
PKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAV
QKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQ
SRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIS
QLKQKLENLQNLNLPQSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSN
ETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDA
TTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIDEKFQAAVERFVYSCAGYCVATFVLGIG
DRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLH
FQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIDYIRDALTVGKSEEDAK
KYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A674JZZ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Terrapene carolina triunguis|TrEMBL
MPPGIYCPVEFWSKEENQTIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVRDPEVNDFRAKMRQFCEEKAAKRQQLSWMAWMEYNFPLQLEPLAKGPRT
GPLRVPNKNIFVNVKFESGGESFTFQVSPKEFPVMLMSYAIKKQATVFRHQTVESPEDYT
LQVKGKCEYLYGNYPLYQFQYIRSCLHHGLMPHLTMVHFSSIIAMRDEQTNCTAHTPKMV
SKPPPLPKKKPTHESLWSLNQPFYIELVQGSKVNADERMKLVVQAGLYHGNEMLCKMVSS
AEVNVCSEPVWKQRLDFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQSNPNTESAAALVICFPSVLL
HPVYYPSFEQLLELGRNGDYTRKQQLREILERRSHTELYEHEKDLVWKMRFEIRDQYPEA
LAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFTINSLKKLTD
DELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPAVALRFG
LILEAYCRGSNYHMKVLMKQGEALNKMKALNDFIKVSSQKATKPQAKEMMHVCMKQETYL
EALSNLQCPLNPTVILAEVCVDHCTFMDSKMKPLWIVFNNEEAGGRGVGIIFKNGDDLRQ
DMLTLQMIQLMDVLWKQEGLDLSEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIR
ETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRDYCEK
AYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEA
LRESWKTKVNWLAHNVSKDNRQ
>A0A6P6DKY9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Octodon degus|TrEMBL
MLWKQVHNYPMFNLLLDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCD
PGEKLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEEKIQSLVGLSWIDWLKQTYP
PEHDPSTLENVQDKLYGGKLIVAVHFENSQDVFSFHVSPNMNPIKVNELAIQKRLTIHGK
EDEARPADYVLQVIGRIEYVFGDYPLIQFQYIRNCVVNRALPHFVLVECCKIRKMYEQEM
IAIEAAINRNSSNFPLPLPPKKTRIISHVWDNNKPFQIVLVKGNKLNTEETVKVHVRAGL
FHGTELLCKTIISSEISGKNDHIWNETLEFDINTCDLPRMARLCFAVYAVLDKAKTKKST
KTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMG
TVQTNPYTENATALHIKFPDNKKQPCYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPV
LKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQI
WPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALS
RFLLERALANRRIGQFLFWHLRSEVHIPAVSIQFGVILEAYCRGSVGHMKVLSKQVEALN
KLKTLNSLIKLNAVKLNRAKGKEAMHTCLQQSAYREALSDLQSPLNPCIILSELHIEKCK
YMDSKMKPLWLVYTNKVFGEDSVGVIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRML
PYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRA
IEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVP
FILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRKHGNLFITLFALMLTAGLPELTS
VKDIQYLKDSLALGKTDEEALKQFKQKFDEALRESWTTKVNWMAHTVRRDYRS
>A0A8C9L3A6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera tigris altaica|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGAPRAGGPDPHPPLPARPRPLHAPPPLRPPXXXXXXXXXXXXPPQESFTFQVSSKDV
PLALMACALRKKATVFRQPLLERPEDYTLQVNGKHEYLYGSYPLCQFQYICSCLHSGLTP
HPTLASSFPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSE
VSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWAN
LMLFDYKDQLKTGECCLYMWPSAPGLPRREGGARGRGLPAGGVPLGSPPEARAFPSGDGR
ADLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNRPXXXXXXXXXX
AAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDN
RQ
>A0A7L0SFU6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podilymbus podiceps|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYSFPLQLEPTAQSLGA
GPLHTSTKNIFVNVKFKSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRS
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A1S3QP47|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo salar|TrEMBL
PLFSLVQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNRE
IGFAIGMPICEFEQLKDPEVQDFRRSILSVCREAMEEREGGGADSQALYVYPPNVESAPE
LPQHISCKLDKGRLIVTIWVIVSPSNSKQKYTLKISHDSLPEQLIAEAIRKKTRSMHLSA
QQLRLCVQEYQGQYILKVCGCDEYLLEKYPLSQYKVNIYPL
>A0A091FWP4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Corvus brachyrhynchos|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTVDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHDSSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAVSIVLDRYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMGSIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A091F7F7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Corvus brachyrhynchos|TrEMBL
SRMPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPL
FHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGL
GTGSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPED
YTLQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPK
AASKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVQLP
TSAVFPQDCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTES
AAALVICFPSVAAHPVYYPSFEQVGHRDTFLGGTGIPSLSLPLKEILERRSHTELYEHEK
DLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFP
DRYVGSFAINSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLF
WHLRSEMHVPAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATK
PQTKEMMHMCMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEET
GGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVM
HSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVL
GIGDRHSDNIMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNN
NEKFERFRGYCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDE
EALKHFRLKFNEALRESWKTKVNWLAHNVSKDNR
>A0A7L4DIB9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eurystomus gularis|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKIAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGESEENAKKYFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L3K905|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Drymodes brunneopygia|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAARRQQLGWAAWMEYNFPLQLEPVAKGPGA
GSLQVPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSFAIKKQATVFRHETVQRPEDYT
LQVNGKCEFLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
TKPPPLPKKKPNCGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWRQRLDFDINICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVTLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8D2NLN5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zosterops lateralis melanops|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALKDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKDEEVDPADY
VLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAINR
KSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLCK
TVVSTEISGRSDHIWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKYQ
TIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMERD
PLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPRE
ALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERAL
GNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSL
IKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKP
LWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLATG
DHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLSC
AGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFI
HVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3P4RT01|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gulo gulo|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSVLENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDQPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRII
>A0A8C9ETR8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pavo cristatus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLDTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPVKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQVNSIANPPKMA
VKPPPLPKKKVRGHSEMLTQLTPPSLVHLLGKPDVHLLGKLRCSRDIPRISQDLILFLLF
PSLCVANADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTE
SAAALVVCFPNVASHPVYYPSFEQLLELGRNGEQPRSAPEDPEEKLQLKEILERRSHTEL
YEHEKDLVWKMRYDIRDQYPQALAKLLTITKWNKHEDVAQMISLLQTWPELPVLNALELL
DFSFPDRYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKI
GHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSS
PKATKPQAKEMMHVCMKQETYLEALSHLQSPLNPSIILTEVCRARFLITLRPSFSHGRWG
RTFKNSLSSCEVLVFKVKFHLFLFSDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
EKAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C5T793|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Malurus cyaneus samueli|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRLARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C3N7V4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geospiza parvula|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVNEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPTKNIFVNIRFQSGGESFMFQISPREFPITLMSYAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPNYGSLWSLEQPFYVELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A4W4HKF4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDSEVQDFRRNILNVCKDAVELRDTNGSHSRALYVYPPNVESSPELPKH
IFGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKHPISQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPAD
TFTMPSYSRRISTATPYMNGEASSKSLWAINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDVPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMATVEDHANWMISREMGYSYCQSGPSSRLARDHIITEADIEQLRQLANRDPL
SEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGETDDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A4W4H1C1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MEMDHLAMEFLLPTTNKITKNPDMLQLSVTGNWTVEQVKTQVWLRAVTTNLCPEFYQKYS
PDHCILLYQKKGSWCEIYDKHQVFQTLDCIRYWKALKKDVGKIHLVLRPQPSEESIQYQK
FLNYLIGYDVTDVSNVHDDELEFTRRKLLTPRKIELADRDPKLYSVDPWITTKPLPDYLL
SKITNSHILVVIHKDTSSQTIKVSIEDTPVQVLHSFFLKTANKRALLGLPEDVSESDFVL
RVCGREEYIFGNYAIKDFHWIRQCLKSGEEIHLVLETPPNPDQDVVPKEDWSQVDDCTGV
AGTHEQLTIDEKDHERVFTISMWDCNRKFRVKILGIDIPVLPRNSELIVFVEASIYHGQQ
LLAQERTLPKPFTEEVLWNVWLEFNIKIRDLPKGSRLNLQVSCGKAQTQASKDSTGHDGR
NKGRLLYYVNLLVVDHRSLLRQGDFILHMWKMPEKTEDNSSVNADKLTSATNPNKTTSMA
ITVLLDKYCYPVALPKSRDSRESSDGEEERGNREMPNHLRKQFEQIVVTDPLHPLSIEDK
ELLWHFRQECTRLPTAYPKFLGSVKWGKQEDVMITHRLLERSTAWERSSLDVGLAMQLLD
CHFSDANVRTMAVRKLETLGDDDILRYLLQLVQAVKFEPYHDSALARLLLKRALRSKRIG
HFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGEAMLQDFRKQVEITEALQKVTRDIKAV
SAEKYDVSPQDRCFDQIEQCKVMASKKKPLWLQFKRADPTTLTNDSIGIIFKDGDDLRQD
MLILQILLIMESIWDTESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGA
FKDEILNQWLRDRCVSEDKFQQAVERFVYSCGGYCVATYVLGIGDRHNDNIMITESGNLF
HIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTTGKKSSPNFLQFQDVCVKAYLALR
HHTNLLIILFSMMLMTGMPQLTSTEDIEYIREALTVGCSEDQAQKHFLDQIEICRDKGWT
VQFNWFLHLVLGIKQGVEKRSA
>A0A6P3IQ78|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bison bison bison|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7F8QR29|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptonychotes weddellii|TrEMBL
MELEHYEQPVVLREDNGRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVPRHAPSEETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCSKAPALSGKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHHQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPYFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>Q7SYE7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Danio rerio|TrEMBL
MPPGVYGMQEVWEMEGRQHVNIEFLLPTGIYLNFTVACSDTISTIKKMLWKNAKNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFLPILRLVAREGDRVEKLITTQINQL
IGKGHHEFDSQKNHELNEFRTKMRAFCEEHAYLRQTLPWDKWMEYNFPCDLEPCSSVTQS
GKSRSIKKIFVNVKFEGSEETFVLQQDPQDLPVVLKRNALRKKSTVFRSVKQEKPEDYSL
QVNERWEFIYGKYPLCQFKYIFTCLHGGLTPHLTMVHYSSIVKYQEEQSGLSNQVSRSRA
QSKPPPLPLKRQNTCSLWSIQEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCFDPVWDQKLVFDINVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGPNGEKVIATKEEHQKLKEIVDNKNSTEFFEDEKEPLWKLREELRL
KYPESLPKLLLITKWNKHEDVAQMVGLLQKWPELPALHALELLDYSFPDPHVRFFTIRCL
RKLPDDKLFQYLLQLVQVLKYESYLDCDLTSFLLERALANKKIGHFLFWHLRSEMHVPSV
SLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSASQKATRIQTTEDMKVCIK
QETYMEALSDVVSPLSPSIILCELCADKCKFMDSKMKPLWLMYKSKYDSVGIIFKNGDDL
RQDMLTLQMIQIMDILWKTEGLDLRMQPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNS
AATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRES
GQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRVCCEQAY
KILCRNGTLFVNLFALMKAAGLPELNSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKVNWMMHTFAKDNR
>A0A8C1R6R4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVI
SNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNDLGMNGEKTTKEEMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIR
CLRKLSDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVP
SVSLRFGLILEAYCRGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVC
IKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGD
DLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNS
NSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIS
ETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQ
AYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKVRTAQTGII
>A0A6J0I5U4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lepidothrix coronata|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3B3UQK2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia latipinna|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
YFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRLSEEKMQRMQMMTCNEWLQACFSPQLEPA
ALTTTTDGLNDPPAELKVIIHFDQSQDSTSLKVSSSWTPSELMEMAVKKWLITHAPEEEE
WSGQYVLRVSHCLEFLCGDHPLIQYKYIRTCLQAKEPPHLTLVHTSTIKEMFDKEMSAIS
AVVSRKSSNPPLPLPPKRRVPTQVHTCVWDVSSSFRIVLVKGSKVNAEESAKVQVRAGLF
HGTELLCKPVVSSETSGRSEHTWRDNALEFEISISDLPRMTRLCFAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSPFPIVFPPFDKILEKAAQLARASDSMSIGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHDDMAQLQALLQI
WPKLCPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAERNRKIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALT
KLKSVNELIKLGTLKNARSKTKEAMLTKEAMITCLRQSGYSEALSDLSSPLNPSVLLSDI
SVEKCRYMDSKMKPLWIVYSNKLLNGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEEN
LDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTNSNVAATAAFNKDALLNWLKERNSG
DALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEDAYLILRKNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A1A8B7S2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius furzeri|TrEMBL
MPPGKYGMQEEWEKEGDQNILMDFLLPTGIFLKFPVPRNDTIKNIKKMVWRNAKTEALYC
GLGDPEGYVFTCINDTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNSHISSL
IGKGLHEFEAQKNHEVDEFRSKMRTFCEEKALERHNLPWQQWMEYSFPCDLEPCCSPPVH
GGTKSKHTKKLFINVKFEACDESFMLQQDPLDIPVALMKSALKKRATVFRSVRQEPEDYT
LQVSGRWEFIYGNHPLRQFKYIFSCLRNGQNPQLIMVHHSTISKYQEEQGQLCSQVGKIR
SQSRPPPLPMKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQKLDFDINVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKRADCPI
AWVNTMVFDYKDQLKTGEFILSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPPLDKMIVMERNGDAVFATKVERMRLKEIMDNKNSTEFFEDEKELLWKLRTEV
RDCYPESLSKLLLITKWSKREDVVQMVSLLRNWPDLPAIQALELLDYSFPDPAVRSFTIR
CLRKLSDNELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVA
SVSLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDIVKSGCQKMTVEDLKLCIRQE
SYMEALSNLMSPLNPSIILVELCADKCRFMDSKMKPLWMMYKNPSEHADMVGIIFKNGDD
LRQDMLTLQMIHLMEDLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKHSDTIANIQRNNSN
SAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEWA
YKILCKNGTLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEDEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A8B7F1W6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcebus murinus|TrEMBL
MELENYEQPVVLREDNVRRRRRMKPRSAAASLSPMELIPIEFVLPTSQRHSKSPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQIHLVQRRAPSEETQVFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPSVTSKPLPEYLSKKIANNCIFIIIHRSTTSQTIKVSAEDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDGVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPILSGRVSADTSGPESKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPSPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGFNKERVPFVLTPDFLFVMGTSGKKTSPYFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A6J2HBX9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pipra filicauda|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSTLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTTVSTEISGRSDHVWNEELEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A671F0I4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinolophus ferrumequinum|TrEMBL
MCFNFIMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREASISYIKQLLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVCPDMNPVKINELAIQKRLTIHGKEDE
ISPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLVVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELAQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAISVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6J2M2M2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phyllostomus discolor|TrEMBL
MCFNFIMPPAMADILDIWAVDSQIPSDGPIPVDFLLPTGIYIQMEVPREATISYIKQMLW
KQIHNYPMFSLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWIEWLKQTYPPEH
EPSNLENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQISGRLEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNFPLPLPPKKTRIISHVWENNSPFQIVLVKGSKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NASKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSIQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELHVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEDEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6J2LSP7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phyllostomus discolor|TrEMBL
MPPGVDCPMEFWTSEENQNVAVDFLLPTGVYLNFSVSRNANLSTIKKALWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYCFPLQLEPSARTWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDMPLALMTCALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHRGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGEYCLYMWPSVPDEKGELLNPTGTVCSNPNTESAAALIICLPEVAP
YPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLCLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSIHHMRVLMKQGEALSKLKALNDFVKVSSQKTPKPQAKELLHVCMR
QETYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVMYCNEEAGSNGSVGIMFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C4U2D9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Falco tinnunculus|TrEMBL
MPPGIYCPTEFWAKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLHISTKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKTT
PKPPPLPKKKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARL
CFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKG
ELLNPMGTVQCNPNTESAAALVICFPSVASHPVYYPSFEQLLELGRNGEQPRQKLQLKEI
LERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPEL
PVLNALELLDFSFPDRYVGSFFLQVHLDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRA
LSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALND
FVKASSQKATKPQTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMK
PLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLST
GDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDF
VHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYL
KDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>Q4SP84|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tetraodon nigroviridis|TrEMBL
MPPRPSSGELWGMHLMPPSILVECLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDFRDCNGPHSRALYVYPPNVESSPELPRH
IYNKLDKGQIIVVIWVIVSTSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
VFTMPSYARRISTATPYMNGETATKALWTINGSLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLSYDMYIPDVPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEHF
GCPVKYPDMTIIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDADNEQLRQVCTRDPL
SEITEQEKDFLWRHRCRFYIFFPHTIVWDFGGLRKTEYKFCFHCFRQDCLNMPEILPKIL
LAVKWNSRDEIAQVGSGSRSRGNTSLCSILSGNTIGPRLLQREVTAPVLTGSAVWFQMYC
LLKDWPAIRPEQAMELLDCNFPDPMIRAFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYL
DNPLARFLLKRALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQ
VEAMEKLINLTDLLKQEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLR
LEECRMMSSAKRPLWLNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQ
NQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKN
KGEMYDQAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKF
GYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMM
LGSGMPELQSFDDIAYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQH
AMN
>A0A671T465|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MKAFPSTSAVSTDHIAVEFVLPTTNKNSRNPDTLHIDVTGNWTVEQVKVQIWHRVVTTKL
CPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTLDCIRYWKALRKEVGKIHLVVRTQP
TEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRKLLTPRKIELSDRDPKRYSMDPWMT
TKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDDTPVQVLQSFFAKITNKRAILGISE
DVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKNGEEIHLVLERPPDPEQDVVQKEDW
SQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRKFRVKILGIDIPVLPRNSELIVFV
EASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIKIKDLPKGARLSLQVSCGKAQTQTS
KENECKNKSRLLYYVNLLMVDHRSLLRQGEFILHMWKMPEKSEDNSSVNADKLTSATNPD
KNSSMAVAILLDQYCYPVALPKSKDSPNSEMEGERGQREMPNHMRKQFEQIIATDPLHPL
SSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEAVTITHRLLERSTVWDRSSLDVGLA
LQLLDCHFSDENVRTMAVRKLETLAGDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALR
SKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGEAVLQDFRKQVEMTEALHKVTR
EIKQMSIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDMLILQILLIM
ESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDEILSQWL
REKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDFGHILGN
YKSFMGISKERVPFVLTPDFLYVMSTTGKKSSPHFLQFQSVCLKAYLALRHHTNLLIILF
SMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEMCRDKGWTVQFNWFLHLV
LGIKQGVEKRSA
>A0A671P755|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEMREGGGAHTQALYVYPPNVESSAELPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKITHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDEYLLEKHPLSQYKYIRSCITLGRLPHLMLVSKDSLYSQLPSS
GFMAPSYSRRTPQPSPCPGGGDPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDELQIEEHANWSISRELGYSYCLGLSSRLVCDSSISQADAEQLRTLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQIYCLLKDWPLMQPESAL
ELLDCNFPDPMVREFALRCLIQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIRDKNKGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKNQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A671KA68|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
LDDDEPPVVRREENKRRRRKMKAFTSTSAVLTDQIAVEFVLPTTNKNSKNPDTLHLDVTG
NWTIEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWNEIYDKQQVFQTLDCIR
YWKALRKEVGKIHLVVRQQPTEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRKLLTP
RKIELSDRDPKLYSMDPWITTKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDDTPVQ
VLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKNGEEI
HLVLERPPDPEQDVVQKEEWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRKFRV
KILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIKIKDL
PKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVDHRSLLRQGEFILHMWKMPE
KSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERGQREM
PNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEAVAIT
HCLLERSTIWDRSSLDVGLALQLLDCHFSDENVRTMAVRKLETLEDDDVLRYLLQLVQAV
KFEPYHDSALARFLLKRALGSMRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGEA
MLQDFRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDNFKVPY
DPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDMLILQI
LLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDEIL
SQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDFGH
ILGNYKSFLGISKERVPFVLTPDFLYVMCTTDKKSSPNFLQFQNVCLKAYLALRHHTNLL
IILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQFNWF
LHLVLGIKQGVEKRSA
>A0A7K6ZW25|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothoprocta pentlandii|TrEMBL
MPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWQHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRIKMRQFCEERAAKRQQLNWAAWMEYNFPLQLEPLAKGFGT
GPLQTPTKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIANPPKMT
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSIAS
HPVYYPSFEQLLELGRNGEQPRAALEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
VRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPILNALELLDFSFPDRYVGSFAI
NSLKKLTDGELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVEQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALAKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P3IQD7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bison bison bison|TrEMBL
MCFYFMMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISCIKQMLW
KQVTNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPEL
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHSLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMVAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEPLEFDINTCDLPRMTRLCFAVYAVLDKVKTKKSTKTM
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPHALPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKTEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3L8RXK6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chloebia gouldiae|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAVWMEYNFPLQLEPMAKGLGV
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
PKPPPLPKKKPNYVSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSS
SEVSVCSEPVWRQRLDFDIGVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKSDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A663E447|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aquila chrysaetos chrysaetos|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A061I7L5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cricetulus griseus|TrEMBL
MCFSSMMPPAMADILDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLW
KHVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEDKIQSLVGLSWIDWLKHTYPPEH
EASVLENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNLTPIKINELAIQKRLTIHGNEDE
VSPYDCVLQVSGRVEYVFGEHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYAENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANMSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALNNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLRQNAYREALSGLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYSNRGFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRRDYSLLQFTHLGKKI
AIAAAQFCHLLELQARLCSEQQKVEQTTEMSTQSI
>A0A8C2QDE8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cricetulus griseus|TrEMBL
MPPGVDCPMEFWTKEESQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVDDFRTKMRQFCEEVAAHRQQLGWEDWLQYSFPLQLEPSARSWRA
GILRVTNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGRHEYLYGNYPLCQFQYICSCLHSGLTPHLTMVHASSILAMRDEQSNPAPPVQKPR
TKPPPIPAKKPSSVSLWSLEQPFCIELMEGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWRQRLEFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSRKADCPIAW
ANLMLFDYKDQLKTGERRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAP
HPVYFPALEKILELGRHGEQRGRITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQ
EHFPEALARLLLVTKWNKHEDVAQLSQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFA
IKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMH
VPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMH
MCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGSVGI
IFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIAN
IQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERF
RGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKQFR
VKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A672UDI2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MELEDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAANCTVEQMKAQIWMRALEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQNPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKVKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDPKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITAD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A672U2N0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVHDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAVN
RKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYAKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMQTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A672UM08|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
CRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQHDSGVIFNDWQPHELVILLELDL
KFLISSLMVALLKDESFTFQISPNEFPITLMSYAIKKQATVFRHETLEKPEDYTLQVNGK
CEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKTATKPPPL
PKKKVKGGSDPAGSTSNHPLMEMLSLCGNNSWFSLPSSGQLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQVASALSYDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQA
LAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAVNSLKKLTD
HDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFG
LILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMMHVCMKQETYL
EALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQ
DMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVA
TAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQ
LFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMI
LRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRES
WKTKVNWLAHNVSKNNRQ
>A0A3B4ZY78|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Stegastes partitus|TrEMBL
MPPGKYGMQEEWEKEEDQQITMDFLLPTGIFLRFPVSRNDTIKNIKKMVWKNARSEAMYS
GLGDPDGYVFTCIKQTAESEELEEESRRLSDVRPFMFVLRLVAREGDRVEKLTNTQISQL
IGKGLHEFEAQKNHEVDEFRTKMRAFCEEKAQERESLPWQQWMEYSFPCELEPCCSPPDS
WSMKSKKSKKIFVQIKFEASQESFMLQQDPHDLPVALMKSALKKKATVFRSLRQEPEDYT
LQVNGRWEFIYGKHPLCQFKYIFSCLRNGQNPHLTMTHYSTIAKYKEEQTKVCSQASKSR
SLSRPPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPPLDKISDIEKNGDAVYVTKDEYVRLKEIMDNKNYTEFFEDEKELLWKLRTDV
RDRYPESLSKLLLITKWNKREDVVQMVSLLRHWPDLPAISALELLDYSFPDPAVRSFTIR
CLKKLSDDELLQYLLQLVQVLKYESYMDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVA
SVSLRFGLILEAYCRGDIHHIKLLTKQNEALGKMKALSDIVKSGSQKMTVEDLKLCIRQE
SYLDALSDLYSPLNPSILLPEICAEKCRFMDSKMKPLWLMYVNPAIQGDMIGIIFKNGDD
LRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSTN
NAATAAFNKDALLNWLKSKNPEDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQEGKTNNSEKFERFREYCEQA
YKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDCLALGKSEDEALKNFKVKFNEAL
RESWKTKVNWMMHSMAKDNRP
>H9F0X6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca mulatta|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKV
>A0A4U1ED73|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodon monoceros|TrEMBL
KRENTLAINFKMNVLTFCVTQEAEREEFFHETRRLCDLTLFQPFKKVTEPLGNHEEKILN
RETGFAVGMPVCEFDMVKDPEVQDFEEIFSIAMYVYPPNVESSRELPKRIHNKLDKGQII
VVIWVIVSPNDKQKYTLKIKPRSNHDCVPEQVIAEVIRKKIQSMLLSSEQLKLCVLEYQG
KYILKKGSTLNCQWIFTMPSYSRCISTATPYTNGETSTKSLWVINSALRIKILCATYVNV
NIRDTDKIYVRTGRKGAKEEHCPLGWGNINLFDYTDTLVSGKMALHLSPVPHGLEDLLNS
IGVTGSNPNKETPCLELEFDWFGSVVRFPDMSVIEEHANWSVSREAGFSYSHAGLNWPPI
KPQQAMELLDCNYPDPMVQGFAVQCLEKYLTDDKLSQYLILLVQVLNYEQYLDNLLVRFL
LKKALTNQRIRHFFFWHLKSEMHHKTGLACFSSPIAVHVGLKLWEELINLTDILKQEKDE
TQKVQMKFLVEQMRLPDFIDALQGFLLPLNPAYQLGNLRLEECRIMSSAKRPLWLNWENP
DITSTATHYISGSKTRTREKYAAIDLFTCSCAGYCVAIFILGIGDGHNSNIMVKDDGQLF
HTDFGNFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKIRESERFQEMCYKAYLA
IRQHVNLFINLFSMMLGSGMPELQSFHDTAYIRKILALDKTEQEALEYFIKPMMHTMVAG
QQKLIGSSTQLSSML
>A0A4U1ED73|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ceratodon monodon|TrEMBL
KRENTLAINFKMNVLTFCVTQEAEREEFFHETRRLCDLTLFQPFKKVTEPLGNHEEKILN
RETGFAVGMPVCEFDMVKDPEVQDFEEIFSIAMYVYPPNVESSRELPKRIHNKLDKGQII
VVIWVIVSPNDKQKYTLKIKPRSNHDCVPEQVIAEVIRKKIQSMLLSSEQLKLCVLEYQG
KYILKKGSTLNCQWIFTMPSYSRCISTATPYTNGETSTKSLWVINSALRIKILCATYVNV
NIRDTDKIYVRTGRKGAKEEHCPLGWGNINLFDYTDTLVSGKMALHLSPVPHGLEDLLNS
IGVTGSNPNKETPCLELEFDWFGSVVRFPDMSVIEEHANWSVSREAGFSYSHAGLNWPPI
KPQQAMELLDCNYPDPMVQGFAVQCLEKYLTDDKLSQYLILLVQVLNYEQYLDNLLVRFL
LKKALTNQRIRHFFFWHLKSEMHHKTGLACFSSPIAVHVGLKLWEELINLTDILKQEKDE
TQKVQMKFLVEQMRLPDFIDALQGFLLPLNPAYQLGNLRLEECRIMSSAKRPLWLNWENP
DITSTATHYISGSKTRTREKYAAIDLFTCSCAGYCVAIFILGIGDGHNSNIMVKDDGQLF
HTDFGNFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKIRESERFQEMCYKAYLA
IRQHVNLFINLFSMMLGSGMPELQSFHDTAYIRKILALDKTEQEALEYFIKPMMHTMVAG
QQKLIGSSTQLSSML
>A0A8J8XK18|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca mulatta|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C4D2J2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPRPSSGELWGIHLMPPKILVDCLLPNGMILTLECLREATLITIKHDLFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLMKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESSSELPKH
IYQKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMATVEDHANWIIAREMGYNYCQSGQSNRLVRDLVMTEGEIEQLRQVGNRDPL
SEITEQEKDFLWRHRHYCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRFEECRIMSSAKRPLW
LNWENPDIMSESLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A8C4C6A8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
LTLNCSRETVPVTTDCKSRRRRRKMKAFTSSSAVGSEQLTVEFVLPTTSKTSNAPDTLNL
EVAGNCTVEQVKAQVWLKAVADQISPQFYEKYSPDHCILCYQKKGSWCEIYDRHQVFQTL
DCIRYWKVLKKDVGKIHMYRRPQPSEESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDARLYSMDPWVTTKPLPEYLTSRISNGHVLLVIHRNTSSQTIKVSIDD
TPFQVLQSFFTKIANKKALLDIPENVTESDYVLRVCGREDYVFGNYAIKDFHWVRQCLKN
GEEIHLVLESAPNPDQDVVEKEDWSQVDDCTGVAGTHEQLTIDEKDHDKVFTISMWDCNR
KFRVKVLGIDIPSLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNAWLEFNIK
IRDLPKGSRLSLQVSCGKAQTQTSKVSNLDGSFDGRCKSRLLYYVNLLLVDHRSLLRQGE
FVLHMWKMPDKSEDNSSVNADKLTSATNPDKTSSMAVVIMLDKYCYPVALPKSPESRDSE
AEGDRGQREMPNHLRKQFQQIVSTDPLHPLSPEDKELLWHFKQECLRNPKAYPKFLGSVK
WGKQEAVMTTHQLLERSTTWDRSQLDVGLAMQLLDCHFSDTNVRSMAVRKLETLDDDDVL
RYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVIL
EAYLRGCGNAMLQDFKKQVEITEALQNVTREIKAISVEKYDVSAQVVLQLRQKLESLQSS
GLPESFRVPYDPGLRAGGLVIEQCKVMASKKKPLWLQFKPADPTTLSSDTIGIIFKDGDD
LRQDMLILQILLIMESIWEAESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSIVG
NTGAFKDEILSQWLRDKCVSEDKFQQTVERFVYSCSGYCVATYVLGIGDRHNDNIMVTEA
GNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFLKFQEVCVKAY
LALRQHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEDDAQRHFLDQIEICRD
KGWTVQFNWFLHLVLGIKQGVEKRSA
>W5PCR4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ovis aries|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVXXXXXXXXXXXXXXXXXX
XXXXXXXXXXTPTPPNPTPDPGADLAPCLSGLHEFDSLQDPEVNDFRGKMRQFCEEAAAR
RQQLGWEAWLQYSFPLQLEPSARSWGPGTLRIPNRALLVNVKFEGSEESFTFQVSTKDVP
LALMACALRKKATVFRQPLVEQPEDYTLQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPH
LTMVHSSSILAMRDEQSNPAPQVQKPRTKPPPIPMKKPSSVSLWSLEQPFYIELIHADER
MKLVVQAGLFHGNETLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVI
EKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGT
VRSNPNTESAAALVIFLPEVAPHPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERR
GSGELYEHEKDLVWKMRHEIQEHFPEALARLLLVTKWNXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXVPDAALAPSLTARILLQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIK
SLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVP
SVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVCSQKTPKPQAKELMHLC
MRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCETAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>W5PBG2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ovis aries|TrEMBL
MCFYFMMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISCIKQQML
WKQVTNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPG
EKLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPE
LEPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKED
EVSPYDYVLQVSGRVEYVFGDHSLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMVA
IEAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFH
GTELLCKTVVSSEISGKNDHIWNEPLEFDINTCDLPRMTRLCFAVYAVLDKVKTKKSTKT
MNPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTV
QTNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLK
EILDRDPLSQLCENEMDLIWTLRQDCRENFPHALPKLLLSIKWNKLEDVAQLQALLQIWP
KLPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRF
LLERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKL
KTLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYM
DSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPY
GCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIE
EFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFI
LTYDFIHVIQQGKTGNTEKFGRNLRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELT
SVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7L3JGD3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Thalassarche chlororhynchos|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDDPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQGICQ
>A0A3P9IUN8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETCYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDFEVQDFRRNILNVCKDAVELRDANGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYSQLPTD
SFVMPSYCRRISTATSYMNGEAAPKSLWTISGGLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLNYDMYILDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYNHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEHF
SSPVKYPDMNAVEEHANWTISRELGFNYNTSGQSNRVARDHALTDSDSEQLKQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKFLADDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNRGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKGEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A3P9HJ96|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MPPRPSSGELWGMHLMPPSIVVDCLLPNGMILSLECLREATLVTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILSREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDNNGPHSRALYVYPPNVESSTDLPRH
IYNKLDKGQIIVVIWVIISPSNDKQKYTLKISHDCVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQFKYVRSCIMLGRMPNLMLMSKDSLYSQLPSD
NFTMPSYARRISTATSYMNGETSSKNLWTINGMLKIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLSYDMYILEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEQF
SSPVKFPDMAYVEEHANWNISRELGFNYSHTGLSNRLARDNPLTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHSCINIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWIKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKEDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A3P9LUK4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETCYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDFEVQDFRRNILNVCKDAVELRDANGPHSRALYVYPPNVESSQELPKH
IYSKLDKGWVTGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSP
EQLKMCVQEYQGKYILKVCGCDEYLLEKYPISQYKVKRSATMA
>A0A093P107|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pygoscelis adeliae|TrEMBL
SRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGL
GTGPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPK
MAAKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQGLSGLSKSSGLRLSPVCALPCDSHEQKLQLKEILERRSHTELYEHEKD
LVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPD
RYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFW
HLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKP
QTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEERG
GGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMH
SDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLG
IGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNN
EKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEE
ALKHFRLKFNEALRESWKTKVNWLAHNVSKDNR
>A0A7L2GDP4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nyctibius grandis|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGRIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTVDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNHQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHNVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGM
>A0A8C8XLQ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera leo|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERKVFGIQNNLPQPFKQHVLNLKCILYFAKTRGRNALLQLPTL
AL
>A0A8C5HCJ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
MDSELMQVSDEEPELLQEDSLTRRRRRRRKKAITSPSCASMDHITVEFILPTNSHGGSGP
DSLQLEVAGNWTVEQVKAQVWLKAVTLNLSFDFYQRLSPDHCILLYQKKGTVCEIYDKHQ
VFQTLDSLKKDVGRIQLVPCPQPSDESLQYQRDLNYLIGYDVTDVSNVHDDELEFTRRKL
LTPRRIELLDRDPRLYSMDPWVTCKPLPKHLLSKVNNGHILLVIHMSTASQTIKVSINDT
PSQVLMSFFTKTANKRALLGIPDNISESDFVLRVCGREEYLYGERPLQNFNWIRQCLKNG
EEIHLVLTAPPDPAMDLVQREDWAQVDDCTGVAGTHEQLTIEEKDHERVFTISMWDCNRK
FRVKVLGIDIPALPKVPELIVFIEASIFHGQQLLAQERTTSKSFSEEVLWNCWLEFNIKI
KDLPKGARLNLQVICGKQQQPSNSKGGSFQNNHPSRLLYYVNLLLVDHRSLLRQGEFILH
MWKMPEKSDESSSSINADKLTSATNPDKASSMAVVILLDKYCYPVVLPKSRESVSAAKEA
EGCDRGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLSSVR
WGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSIAVRKLETLDDDDVL
RYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSKHYQQRYAVLL
EAYLRGCGGDLLTDFQKQVITLQKVTREMKATSADKYDVTAQVVFLLRQKLETLQSTGLP
QSFRVPYDPGLKAGALLIEQCKVMASKKKPLWLQFRRADPTSRSKDPIGIIFKDGDDLRQ
DMLILQILLIMESIWEAESLDLCLLPYGCISTGNKIGSCTHRQEVAAP
>A0A7K5E226|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Polioptila caerulea|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKSIFVNVRFQSGGESFTFQISPWEFPITLMNYAIKKQATVFRHETLQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGAEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L2J2M3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cinclus mexicanus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GTLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIRKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAILAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWRQRLDFDINVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEIHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6A4SDA9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MGTQGVDPSTSPLPPHPRNIPPPLRLDVGDAGRPCSPPAGSHHPSLTPTLTPAAFSLDQT
IFNLQASDSPTNNSLVAIDNRIQQAMVAQCLGMMVSLECLRETPLISIKQQLFTEARKYP
LYHLLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREI
GFAIGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNLESSPQL
PQHIYSKLDKGRLIVTIWVIVSPSNSKQKYTLKLRLCVQEYQGQYILKVCGCDEYLLEKY
PLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPASGFVTPSYSRRTPQPSPCPGGGDGSP
PRSLWAFNTLLRVRLLCATYVNVNIRDIDKVGFCSSWNEWLTYDIYLADLPRSARICLSI
CSVKGRKGAKEEHCPLAWGNVNLFDYKDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNP
NKETPCVELEFSWFNQTVVFPDEQQIEEHANWTISRELGYNYCPGLTSRLACDVSVSAAD
AEQLRCLCSKDPLYELSEQEKDFLWRHRHYCVNIPESLPKLLMSVKWNSRDEASQMYCLL
KEWPLMEPESALELLDCNFPDPMVREFALRCLVKGLTDDKLSQYLLQLVQVLKYEMYLDN
PLARFLIKKALTNQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQTQ
MKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSE
LLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRYDRAIDLFTRSCAGYCVAT
FILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGV
QESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLAL
GVGEHPLQYNYTFWFSRRTPTRPASSQSYEQNIRQIGIVASVEQFWKFYSHLVRPGDLSG
HSDFHLFKEGIKPMWEDDFNRSGGKWIIRLRKGLASRFWENIILAMVGEQFMVGEEICGA
VVSIRFQEDILSIWNKTSNDQTTTSRIRDTLRRVLNLPANTIMEYKTHNDSLRFRSGLET
FTLEVILS
>A0A8C3UA28|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Catharus ustulatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8D3B7B3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPGKYGMQEEWEKEGVQEIMMDFLLPTGILLKFPVSRNDTIKSIKKMVWKNARSEALFC
GLGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRAEKLINTQISLL
IGKGLHEFEAQKNHEVNEFRTKMCIFCEEKAQERQMLPWQQWMEYNFPCDLEPCCTPPHS
GSLKSKNTKKFFINVKFEACDESFMLQQDPQDHPVALMRSALKKKANVFRSVRQEPEDYT
LQVNGRWEYIYGKHPMCQFKYIFSCLRNGQNPHLTMVHHSTISKFQEEQGQMCSQEYKSR
SLSRPPPLPLKKLNTSSLWSITEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFANI
RPHPLYYPPLDKVLRNGDAASVTKEEYMKLKEIMDNKNYTEFFEDEKELLWHLRTEVRDR
YPENLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAIRSFTIRCLR
KLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVT
LRFGLILEAYCRGNIHHIKLLTKQNEALSKMKTLSDFVKSGSQKLTAEDLKLCIRQESYL
EALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNNWAPEDMVGIIFKKGDDLRQ
DMLTLQMIQLMETLWKREGLDLRMIPYGCLSTGNKMGLIEVVENSDTIANIQRNNSNSAA
TAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQ
LFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKI
LCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRES
WKTKVNWMMHSLAKDNRP
>A0A7K7YL12|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Thryothorus ludovicianus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMRQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGTGS
LQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETLQKPEDYTLQ
VNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGPEMLCKTVSSSE
VSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAWVN
VMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLREILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VQETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7K5C3A1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Motacilla alba|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMECNFPLQLEPAPKGLSS
LQIPTKNIFVNVRFQSGGESFMFQISPWEFPITLMGYAIKKQATVLRPETVQKPEDYTLQ
VNGKCEYLYGNYPLYQFQHIRSCLQRGLTPQLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSSSE
VSVCSEPVWRQRLAFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAWVN
VMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A2J8WGL8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pongo abelii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A673N2F3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MEHQASDDEPPVVRREENKRRRRKMKAFTSTSAVLTDQIAVEFVLPTTNKNSKNPDTLHL
DVTGNWTIEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVVRQQPTEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLSPRKIELSDRDPKLYSMDPWITTKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKN
GEEIHLVLERPPDPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERG
QREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEA
VAITHCLLERSTIWDRSSLDVGLALQLLDCHFSDENVRTMAVRKLETLEDDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALGSMRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRG
CGEAMLQDFRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDSF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLCEKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFLGISKERVPFVLTPDFLYVMCTTDKKSSPNFLQFQAYLALRHHTNLLI
ILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQFNWFL
HLVLGIKQGVEKRSA
>H2PXY8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan troglodytes|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVRPPRPSPCFPGPQPSSVSLWSLEQPFRIELIQGSKVNAD
ERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYA
VIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPT
GTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKLPGGMLLASCEWRPELLWMRLHAEDS
APSRMIGVAMPGLGVLPGLVQAPGDAECSCLLQILELGRHSECVHVTEEEQLQLREILER
RGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVL
SALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRA
LANRKIGHFLFWHLRYSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>K7A3X0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan troglodytes|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>H2QNS1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan troglodytes|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEECNKLYLNYNLFDDIAYIRKTYTSWAGHTKGLSIFHQL
NIKQHHFKNIHL
>A0A8C4W396|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gopherus evgoodei|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVCPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWVINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMTVIEEHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8J6G0R7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microtus ochrogaster|TrEMBL
MPPGVDCPMEFWTKEESQNVAVDFLLPTGVYLNFAVPRNANLSSIKQVLWRNAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEESFTFQVSTKDMPLALMACALRKKATVFRQL
LVEQPEDYTLQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHKSSILAMRDEQSN
PAPQVQKPRTKPPPIPAKKPSSVSLWSLEQPFCIELIEGSKVNADERMKLVVQAGLFHGN
EMLCKTVSSSEVNVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVVEKAKKARSTKKKS
KKADCPIAWANLMLFDYKDQLKTGERRLYMWPSVPDEKGELLNPAGTVRSNPNTERAAAL
VICLPEVAPHPVYFPALEKILELGRHGERGRITEEEQLQLREILERRGSGELYEHEKDLV
WKMRHEVQEHFPEALARLLLVTKWNKHEDVAQMVYLLCSWPELPVLSALELLDFSFPDCY
VGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHL
RYSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQ
TKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCSVEQCTFMDSKMKPLWIMYSSEEAG
SAGTVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVL
HSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVL
GIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINHFVHVIQQGKTNNSEKFERFRGY
CERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKF
NEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K9KAD5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicaeum eximium|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSNFSSMELISIEFILPTNNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAVEMSQSTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CIPYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWVRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISVVLDKYCHPVALPKHRISSE
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K5CY83|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pachyramphus minor|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K5SNV9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Urocynchramus pylzowi|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSEFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNIRFQSGGESFMFQISPWEFPITLMSYAIKKQATVFRPETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGAEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6F9CL68|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coregonus sp. 'balchen'|TrEMBL
MPPAMTDLLDMWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGMFRISEEKMQRVQLMTWSEWLQACFSPQLEPGGGATDGVNDKQAEASLKVTMHFDQSQ
DTASLKVCPSTSPTELMEQAVRKWLMTHGPEEDGRQAEQYVLRVSDKLEFLCGDHPLIQY
KYIKACLQAKECPHLTLVQVSTVQTMFEKEISAIGAVVNRKSSNPPLPLPPKRRGPSQVQ
TCVWEVSTQYKIVLIKGSKVNAEETAKVQVRAGLFHGTELLCKPAVSSESSGHTEHVWNR
TLEFDIAVSDLPRMTRLCFAVYAVMDKVKKQNWSSFPDELEEMLNPIGTIQTNPYTENAT
ALHIHLPNYNPQPIVFPPFDKGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCM
ENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVGC
LRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLNRAQSEMHMPVVSVQFSLILEAYCR
GSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTET
LSDLHSPLNPSVLLSGINVEKCRYMDSKMKPLQDMLTLQILRLMDLLWKEANLDLRIVPY
GCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFI
LTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTSDS
LALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A3B4AQR5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Periophthalmus magnuspinnatus|TrEMBL
IVGHQRSCTCDLFYSHISGMLVSLECLRETPLIDIKQQLFTEARKYPLYHLLQEESCYIF
VGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPIGNREEKILNREIGFAIGMPVCEFEL
LKDAEVQEFRRSILSVCREAVEEREAGGAHSQALYVYPPNVETSPELPLHLYQRLDQGRL
IVTIWVIVSPSNSKQKYTLKVSHSSLPEQLIAESIRKKSRSMHLSPQQLRLCVQEYQGQY
ILKTPLRHVRQRQHPRHRQGQSVCHLSMS
>A0A7L0U0Z3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chordeiles acutipennis|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVLWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELVDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWIAWMEYNFPLQLEPTAKGLGT
GALHTHNKNIFVNVKFQSGGESFTFQISPAEFPITLMSYAIKKQATVFRHETVENPGDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHKGLTPHLTMVHSSTIIAMRDEQTNCITSPPKMP
AKPPPLPKKKPNYGSLWSLEQSFSIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3P9P479|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia reticulata|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
NFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDGINDQEVKDFRSKMFRLSEEKMQRVQMMTCNEWLQACFSPQLEPA
ALTTITDGLNDRPAELRVFIHFDQSQDSTSLKVSSSWTPSELMEMAVKKWLITHAPEEEE
WSGQYVLRVSHCLEFLCGDHPLIQYKYIRTCLQAKENPHLTLVHTSTIKEMFDKEMSAIS
AVVSRKSSNPPLPLPPKRRVPTQAQTCVWDVSSSFRIVLVKGSKVNAEESAKVQVRAGLF
HGTELLCKPAVSSETSGRSEHTWRDNALEFDISISDLPRMTRLCFAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSPYPIVFPPFDKILEKAAQIARASDSMSIGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRHDCREIFPQCLPKLLLSVKWSKHDDMAQLQALLQI
WPKLCPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAERNRKIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALT
KLKSVNELIKLGTLKNARSKTKEAMLTKEAMITCLRQSGYSEALSDLSSPLNPSVLLSDI
SVEKCRYMDSKMKPLWIVYNNKLLNGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAN
LDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTNSNVAATAAFNKDALLNWLKERNSG
DALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGNTEKFGSFRQNCEDAYLILRKNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C8C629|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPRPSSGELWGMHLMPPSIMVDCLLPNGMILTLECTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDAEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVSIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A7K5N5E1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chroicocephalus maculipennis|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQPFYVELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFRYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C8H5D6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MQRSSSERKIRRRRRKMKAFTSTLSVAVDQIAVEFVLPTTTKSSRSPDTLLLEVAGNWTV
EQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQTLDCVRYWKA
LKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPRKIE
LSDRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSIDDTPVQVLQT
FFTKISNKRALLGVPENVCEADYVLRVCGREEYIYGNHPVRNFHWVRQCLKNGEEIHLVL
ELAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVYTISLWDCHRKFRVKVLG
IDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNAWLEFNIRIRDLPKGA
RLSLQVSCGKAQTQISKGGGGSGSGSGSHDGSKTKSRLLYYVNLLLVDHRSLLRQGEFIL
HMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYPVALPKSRDGKAAGGEG
REAEGGERGQREMPNHLRKQFEVIVETDPLHPLSQEDKELLWHFREECMRHPRAYPKLLG
SVLWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLETLGDD
DVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYA
VLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQVVFQLRQKLENL
QTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTTLSSDTIGVIFKD
GDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQS
VVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLGVGDRHNDNIMI
TESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCV
RAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEEAQRHLLDQIEI
CRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A852HEA4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nicator chloris|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGRTPHLTMVHSSAIIAMRDEQSNCITSPPKAA
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVCS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQHPWALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKSDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2U3YQH7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptonychotes weddellii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A851UU44|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Copsychus sechellarum|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTADFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQLHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GDYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYELLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQEAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFQKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A671U0D2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MPPGKYGMQEEWEKEGDQGIVMDFLLPTGIFLKFPVSRHDTIKSIKKMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEVKAQERQALPWQQWMEYSFPCDLEPCIFMSHT
VCVKISRYDGAAHIESSTESFMLQQDPQDLPVALMRSALKKKATVFRSVRQEPEDYTLQV
NGSWEFIYGNHPMCQFKYIFSCLRNGQNPHLTMVHHSTISKYQEEQGRMCSQVFKSRSLS
RPPPLPLKKVRGQRTDLVVQAGLFHGSELLCKVVTSSEVTVSSEPLWDQKLEFDINVADL
PRMSRLCFALYAVIEKAKKPRGTKKKNKKALFYLYITPRKEGIDCPIAWVNTMVFDYKDQ
LKTGEFLLSTWPSVPGDLLNPMGTVEKNPNVDSAAGLLIRFSNIRPHPLYYPPLDKISDV
ERNGDAAIATKEELKEIMDNKNYTEFFEDEKELLWKLRTEVRDRYPESLSKLLLITKWNK
REDVVQMVSLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLRKLSDDELLQYLIQLVQ
VLKYESYLDCDLATFLLERALSNRRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIQ
HIKLLTKQNEALGKMKALSDFVKSGSQKMTVDDLKLCIRQESYLEALSDLLSPLNPSIIL
TEICADKCRFMDSKMKPLWLMYKNTCAQGDMVGIIFKNGDDLRQDMLTLQMIRLMENLWK
KEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLTWLKSK
NPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRK
LGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMK
AAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDN
RP
>A0A8C9PNE3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Spermophilus dauricus|TrEMBL
MPLGIDCPMEFWTEVEKNQSVVVDFLLPTGIYLSFPVSRNANLSTIKQMLWHEAQNEPLF
HMLRDPEAYVFTCVNQTAEQQELEDKQQRLCDVQPFLPMLRLVTRQGDRMEKLINSQISL
LIGKGLHEFDCLQDPEVNDFRTKMCQFSEEAAAHRQQLGWEAWLQYSFPLQLEPSTRSWG
DSNTSQISNPDLLVNVKFEGSRESFTIQVSTKDVPLALMACALQKKAKVYQHLTMEQPED
YVLQVNGRHEYLYGSYLLCQFKYICSCLHSGQTPHLTMVHSSSILAMRDEQSKPAPQVQK
PHTKLPPIPMKKPSSVSLWSLGQPFCIELIQGSKINADEQMKLVVQAGLFHGNEMLCKTM
SSLEVSVCSEPMWKQHLEFDINICDLPRMARLCFALYAVMEKAKKVYSRKKKSKKEDCPI
ARANLMLFDYKDQLKTGELCLYMWPSMRKETLEVLNPMGTVHSNPNTESAVTLVIYLPEM
APHPVYYPALEKILELGHHWEHGPTTKEEKLQLQGILEQRGSGELYEHEKDLVWKMRHEV
QEHFPEALAHLLLVTKWNKHEDVAQMLYLLCSWPELPVLNSLELLDFSFPNCHVGSFAIR
SLQKLTDDELLQCLLQLVQVLKYKSYLDCELTQFLLDRALANRKIGHFLFWHLRSEMHVP
SVALRFGLIMEAYFRGSTHHMKVLMKQVEALSKLKALSDFVKVSSQKTTKPQTKELMHLY
MRQDTYLEALSHLQSPLDPSTMLAEVCVERCTFMDSKMKPLWIMYSSEEAGSADSVGIIF
KNGDDLRQDMLTLQMIQLMDALWKQEGLDLREALDRAIEEFTLSCARYCVATYVLGIGDR
HSDNIMIRENGQLFHIDFGHFLGNFKTKFGIKRERVPFILTHDFVHMIQQGKTSDNEKFE
RFRGYCEQAYSILQCHGLLFLQLFALMQAAGLSELSSSKDIQYLKDTLALGKTEEEGLKH
FRVKFNEALRESWKTKVNWLAHNLTKDNRQ
>A0A8C8U0X7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Peromyscus maniculatus bairdii|TrEMBL
MPPAMADILDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRRKMRKFSEDKIQSLVGLSWIDWLKHTYPPEHEPSVLE
NLEDKLYGGKLIVAVHFENSQDVFSFQVSPNLTPIKINELAIQKRLTIHGREDEANPYDC
VLQVSGRVEYVFGEHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINR
NSSNLPLPLPPKKTRVISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQ
TIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYAE
NATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVSCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALD
NRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLI
KLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPL
WLVYSNRGFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGD
RSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCA
GYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>F7G3I5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodelphis domestica|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVHAPHSRALYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASTKSLWVVNSALRIRILCATYVNVNIRDIDKIYVRTGI
CHGGEPLCDNVNTQRVPCSNPRWNEWLMYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMAVIEEHANWTVSRELGFNYSHAGLSNRIARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVSIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A5F8GWH0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodelphis domestica|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISHIKQMLW
KQAHSYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKVVTRNCDPGE
KLDSKIGVLIGKGLHEFDALEDPEVMEFRSKMRQFSEEKIQSLIGLSWMDWLKHTYPPEQ
EPSIPENLEDKLYGGNLVVAVHFENCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDE
VDPYDYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPKLTLVECCNIKKMCEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISNVWENTQPFQIVLVKGTKLNTEETVKVHVRAGLFHG
TELLCKPVVSSEISGRNDHVWSEPLEFDINICDLPRMARLCFAVYAVDKVKTKKSTKAIN
PSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDIILHSWSSFPDELEEMLNPMGTVQT
NPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSGNVSSRGGKKFHVVLKEI
MERDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSVKWNKLEDVAQVSSSSIWPKLP
PREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLD
RALANRRIGQFLFWHLRSEVHIPAFSVQFGVILEAYCRGSVGYMKVLSKQVEALNKLKTL
NSLIKLNAMKLNKAKGREAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSK
MKPLRIVYNNKVFGGDPVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCL
ATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFT
LSCAGYCVASYVLGIGDRHSDNIMVRKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTY
DFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQ
YLKDSLALGKSDEEALKQFKQKFDEALRESWTTKVNWMAHTMRKDYRS
>A0A5F8GB49|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodelphis domestica|TrEMBL
MPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISHIKQMLWKQAHSY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKVVTRNCDPGEKLDSKI
GVLIGKGLHEFDALEDPEVMEFRSKMRQFSEEKIQSLIGLSWMDWLKHTYPPEQEPSIPE
NLEDKLYGGNLVVAVHFENCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEVDPYDY
VLQVSGRLEYVFGDHPLIQFQNVWENTQPFQIVLVKGTKLNTEETVKVHVRAGLFHGTEL
LCKPVVSSEISGRNDHVWSEPLEFDINICDLPRMARLCFAVYAVDKVKTKKSTKHYPVAW
VNTMVFDFKGQLKSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIKFPENKK
QPYYYPPFDKVSELPCKIKILSSFLLFSHFSCGKKFHVVLKEIMERDPLSQLCENEMDLI
WTLRQDCRENFPQSLPKLLLSVKWNKLEDVAQVTTGSSSIWPKLPPREALELLDFNYPDQ
YVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLDRALANRRIGQFLFWH
LRSEVHIPAFSVQFGVILEAYCRGSVGYMKVLSKQVEALNKLKTLNSLIKLNAMKLNKAK
GREAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLRIVYNNKVFGG
DPVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTS
ETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGI
GDRHSDNIMVRKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTE
KFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSDEEA
LKQFKQKFDEALRESWTTKVNWMAHTMRKDYRS
>A0A6Q2XQL3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPRPSSGELWGMHLMPPTIQVDCLLPNGMILTLECTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPVD
TFAMPSYARRISTATPYMNGETAAKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANWNISRELGFNYSHSGLSNRVARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVSIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVSVLQPSITLPSVMCLRLEECRMMSSAKRPLWLNWENPDMMSELLFQSNEI
IFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQ
IQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRSCAGYCVATFILGIGDRHNS
NIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFER
FQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYF
MKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A6Q2ZD82|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPVEYGMLGEWEKEGDLEIMMDFLLPTGIFLKFSVSHNDTIGAIKKMVWSNASNEPLYG
ALSDMDAYVFTCINSTAEREELEDETRRLCDVRPFMPVLRLVAREGDRVEKLTNTQISLL
IGKGRNYYYYSLHKLMKIVNEFRAKMRSFCEERALERQQLPWYQWMEYSFPCELEPCVLL
AEPGGIKTKCKKIFVNVKFEASDESFMLQHEPQDLPVTLMRSALKKKATVFRSVHQEKPE
DYTLQVNGRWEFIYGKYPLCQFKYIFSCMRGGQTPHLTMVHHTTIVKYQEEQGRLASQVS
RCRSLSKPPPLPLKKNTSSLWSIEEPFNIHLIQGNRVNADEGMKLMVQAGLFHGSEMLCK
VVTSGEVNVCSEPLWDQKLVFDINVSDLPRMSRLCFALYAVIEKNKKPRSTKKKNKKADC
PLAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNIDSAPGLLIRFP
NIRPYPLYYPPLEKVRLSFPAHSQTLFSNWYLDNKNYTEFFEDDKELLWNLRGVVRQRYP
ESLSKLLLITKWNKREDVAQMVDLLHKWPELPALHALELLDYCFPDPRVRSFTIRCLRKL
SDEELLQYLLQLVQVLKYESYLDCDLTTFLLERALANKRIGHFLFWHLRSEMHVSSVSLR
FGLILEAYCRGNICHIKSLWKQNEALNKMKAVNDFVKSGWQKTSRQQMTDDMKLCIKQEA
YIWALSNLLSPLNPSIILSEICADRCKFMDSKMKPLWLMYKNKCVQGEAAGIIFKNGDDL
RQDMLTLQMIQLMENLWKKEGLDLRDKLDNAIEEFTLSCAGYCVATYVLGIGDRHNDNIM
IKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRAYC
EQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFN
EALRESWKTKVNWMMHSLAKDSRL
>A0A8C4MGF8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Equus asinus asinus|TrEMBL
MEMENYEQPVVLREDNRRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSGAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLLYWKVLHRSPGQIHVVQRRAPSEDTVAFQQQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLSKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDQVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKVRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASADTPSSESKGKVQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRSTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCSFPDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALVRFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGMAMLHDFTQQVQVIEVLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKRADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKERCPLEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A2K5EQ49|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aotus nancymaae|TrEMBL
MELANYEQPVVLREDNRRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRNCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSLGQIHLVQRRAPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVATRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKYLMDIPESQSERDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFNIKI
KDLPKGALLNLQIYCGKAPALSSKAPAESPSSESRGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCYPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRTIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVIAQLKQKLENLQNSHLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSKETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A3Q3J307|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monopterus albus|TrEMBL
MPPRPSSGELWGMHMMPPKILVDCLLPNGMILTLECLREATLITVKHELFREARKYPLYH
LLQEESSYIFVSVTQEAELEEFYDETRKLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEVVDLRDSNGPHSRALYVYPPNVESSSELPKH
IYSKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMTKDDLYSQLPMD
SFTMPSYARRISTATPYMNGETGTKSLWIINGALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRLWNEWLNYDMFIPDIPRAARLCLSICSVKGRKGAKEEH
CPLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGITGSNPNKETPCLELEFDH
FSCPVKFPDMTTIEDHANWNISRELGFNYCHTGLSSRLVRDNPLTDSDAEQLRQVCNRDP
LSEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAM
ELLDCNFPDPMIREFAVKCLEKYLIDDKLSQYLIQLVQVKFYENSIFHYGTHNPFFFGLH
IFRSEMHNKTVSQRFGLLLESYCRACGVYLKHLRRQVEAMEKLINLTDLLKQEKKDETQK
VQMKFLIEQMRRPDYMDALQGFNSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWENPDMM
SELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIE
VVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRSCAGYCVATF
ILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQ
ECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALD
KTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A851MIS4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Campylorhamphus procurvoides|TrEMBL
MELEDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMILLE
IAGNSTVEQMKAQVWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRLKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNVWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIPSD
AQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPALRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKEKCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8B7F1X9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcebus murinus|TrEMBL
MELENYEQPVVLREDNVRRRRRMKPRSAAASLSPMELIPIEFVLPTSQRHSKSPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQIHLVQRRAPSEETQVFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPSVTSKPLPEYLSKKIANNCIFIIIHRSTTSQTIKVSAEDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDGVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPILSGRVSADTSGPESKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPSPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGNLFHIDFGHILGNYKSFLGFNKE
RVPFVLTPDFLFVMGTSGKKTSPYFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQ
LTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHS
A
>A0A2R9AJ46|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan paniscus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRALPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMRYLLAKFKEGKRFMGDEELSQYLLQLVQVL
KYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHM
KVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCV
ILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLL
WKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLK
EYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFK
SKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFAL
MLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRK
DYRS
>A0A8D0C3R8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salvator merianae|TrEMBL
MPPGIYCPVEFWSKEANRNIQVDFLLPTGIYLNLLVPCSATLSTIKKAVWHHAQYEPLFH
MLSDPDSYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSSGDPEVNDFRAKIHQFCAERAAQRQQLSWRAWMEYSFPVQLEPLAGSPER
KNSLRIPNKNIFVNVKFESGGESFTFHISPKELPMTLMSYAVKKQATVFRHQRINSPEDY
TLQVNGKCEYLYGNYPLYQFQYIHDCLHHGLLPHLTMVHSSSIMALWEEQANGIAHSPKS
VARPPPIPKKKPTSASLWSFDQPYYIDLVQGSKVNADERMKLVVQAGLYHGNEMLCKMVS
SSEVSVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIA
WVNVMLFDYKDQLKTGECSLPMWSSFPDEKGELLNPMGTVQTNPNTESAAALVIHFPSLS
AYPVYYPSLEQILEQGRNGPCPRSVPEDPEEKQQLREILERRSHAELYEHEKDLLWKMRY
QIRDHYPGALAKLLVVTKWNKHEDVAQMVHLLQSWRELPVLNALELLDFNFPDRCVSSFT
VNSLKKLTDVELLQYLLQLVQVLKYESYLDCDLTKFLLDRALSNRKIGHFLFWHLRSEMH
VPSVAIKFGLILEAYCRGSPYHMKALMKQSEALSKMKALNDIVKLSSQKISKLQTKEYMH
ACMRQETYMEALSNIQSPLNPHIILSKVSVELCTFMDSKMKPLWIVFSNKNMGGSNMGLI
FKNGDDLRQDMLTLQMIHLMDILWKKEGLDLRMTPYGCLSTGDKMGLIEAVMDSDTIANI
QLNKSNMAATAAFNKDALLNWLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVVQQGKTNNSEKFERFR
DYCERAYMILRSHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEARKHFQL
KFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8D0C3A3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salvator merianae|TrEMBL
MPPGIYCPVEFWSKEANRNIQVDFLLPTGIYLNLLVPCSATLSTIKKAVWHHAQYEPLFH
MLSDPDSYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSSGDPEVNDFRAKIHQFCAERAAQRQQLSWRAWMEYSFPVQLEPLAGSPER
KNSLRIPNKNIFVNVKFESGGESFTFHISPKELPMTLMSYAVKKQATVFRHQRINSPEDY
TLQVNGKCEYLYGNYPLYQFQYIHDCLHHGLLPHLTMVHSSSIMALWEEQANGIAHSPKS
VARPPPIPKKKPTSASLWSFDQPYYIDLVQGSKVNADERMKLVVQAGLYHGNEMLCKMVS
SSEVSVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIA
WVNVMLFDYKDQLKTGECSLPMWSSFPDEKGELLNPMGTVQTNPNTESAAALVIHFPSLS
AYPLFICHHGARFDGEEDDSFEIQQLREILERRSHAELYEHEKDLLWKMRYQIRDHYPGA
LAKLLVVTKWNKHEDVAQVSSLMVHLLQSWRELPVLNALELLDFNFPDRCVSSFTVNSLK
KLTDVELLQYLLQLVQVLKYESYLDCDLTKFLLDRALSNRKIGHFLFWHLRSEMHVPSVA
IKFGLILEAYCRGSPYHMKALMKQSEALSKMKALNDIVKLSSQKISKLQTKEYMHACMRQ
ETYMEALSNIQSPLNPHIILSKVSVELCTFMDSKMKPLWIVFSNKNMGGSNMGLIFKNGD
DLRQDMLTLQMIHLMDILWKKEGLDLRMTPYGCLSTGDKMGLIEAVMDSDTIANIQLNKS
NMAATAAFNKDALLNWLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIR
ENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVVQQGKTNNSEKFERFRDYCER
AYMILRSHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEARKHFQLKFNEA
LRESWKTKVNWLAHNVSKDNRQ
>A0A851TTZ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Elachura formosa|TrEMBL
KMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLY
QLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVKKKEEKILNREIGF
AIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPK
HIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQL
KLCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPL
DTFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTG
IYHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEH
CPLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDW
FSNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDP
LSEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAM
ELLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDIL
KQEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPL
WLKKKNPDIMSELLFQNNEIILKKRDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVRSSHTIMQIQCKGGLKGAKKINSHTLHQWLKDKNKGDKKKALYDAAID
LFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFV
LTQDFLIVISKGAQECTKKKKFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQS
FDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C7SHR0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGMVWRNASSEPLYGALSD
ADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFDSQKNHEVNEFRTKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEPGGIK
TKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDYTLQV
NGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQVSKSRSLS
KPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVVTSGE
VNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPLAWVN
TMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHP
LYYPHFDKFIQSDHGRFNVKKPDVCHCVQMVAFLQKWPDLPALHALELLDYSFPDPMVRS
FTIRCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSE
MHVSSVSLRFGLILEAYCRGNIYHIKSLCKQNEALNKMKALNDFVKSGWQKTSRQQMTDD
MKLCIKQEAYMEALSYLLSPLNPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDTVG
IIFKNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIA
NIQRNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRH
NDNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFER
FRECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKCPFQNMVMIW
>A0A0P7U185|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MPPAMTDILDIWAADSQLSNEDYVTVDFLLPTGIYIQMEVPREATIQHIKLSAVHEALED
ETRRLCDVRPFLPVLKLDQEVKDFRVKMFRISEEKMQRVQMMTWMEWLQSCFSPQLENGV
IDGLQEKLFDGALKVIMHFDQSQDTASLMVSPTITPRELTEQAVRKWITTHGPEEDESSC
GEFLLRVSNKLEFLYGEHPLIHYKYVRACVIGKDTPHLTLVHCGMVQAMFEKELSAIGAV
VNRKTSNPPLPLPPKRRGPSQMHTCVWDAQTQFKIVLVKGSKVNAEETAKVQVRAGLFHG
TELLCKPSVSTESSGRSEHVWNHALDFDIAVCDLPRMARLCFAIYAVMDKVKKQKSTKNA
HINKYQTIRKAGKVHYPIAWVNTMVFDYRGHLKTGDNILHCWSSFPDELEEMLNPIGTVR
TNPYTENATALHIYFPEYSSCPVVFPPFDKILEKAAEIARRAGRQEVPHRAEGDHGERSP
VAAVREREGPHLDTTLRLQGELPPLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVRC
LKDMSDDELSQYLLQLVQVLRYEPYYDCALTRFLLERAQTNRKIGHFLFWHLRSEIHMPA
VSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKAVNELIKLGTIKNARKTKEAMLTKEA
MLTCLRQTGFTETLSDLHSPLNPSVVLSGINQSVHLQSHLVNELPLTFLCNLRQDMLTLQ
ILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSAAETIANIQLTSSNVAAAAAFNK
DALLNWLKEKNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDF
GHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGNFRQYCEDAYLILRRNGN
LFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVN
WMAHNVAHNRS
>A0A7K9HX76|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bucco capensis|TrEMBL
MELGNYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKAPEIILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQTPSEEVQEFQRQLNSLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFRKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRARAEMPNQLRKQLEEIITTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMDIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPKSFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEERFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8B9PHR2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Apteryx owenii|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKIGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDNSELDFVLRICGRDEYITGETPIKNFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKANLQSHESPNSDLKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESVKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMRSHLMQLETQNTIVTEVVY
RRTIPV
>A0A8B9PHW4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Apteryx owenii|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWQHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRIKMRQFCEERAAKRQQLSWAAWMEYNFPLQLEPLATGLGT
GPLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMNYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCLANPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSIAS
HPVYYPSFEQLLELGRNGEQPRTALEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDGELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTREMMHV
CMKQETYVEALSDLQSPLNPNIILTEVCVEQCTFMDSKMKPLWIVFNNEETDGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LTKSNMVATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALAKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3N0Z2H9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabarilius grahami|TrEMBL
MEQLASDDEPPVVRREENKRRRRKMKAFTSNSAVSMDHIPVEFILPTTNKNTKTLDTLQL
EVTGNWTVEQVKVQLWHRAVTTKVCPEFYQKYSPDHCILLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVVRPQPTEHSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDPKLYSMDPWMTSKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVGVLQSFFTKITNKRALLGISEDVSESDFVLRVCGREEYLYGNCAIKDFHWIRQCLKN
GEEIHLVLEPPPNPEQDVVQKDDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTNSKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLLVDHRSLLRQGEFILHMW
KMPEKNEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERG
QREMPNHLRKQFEQIIATDPLHPLTSEDKELLWHFRQECMRDPKAYPKFLSSVKWGKQEA
VAITHCLLERSTVWDRSILDVGLALQLLDCHFSDENVRSIAVRKLETLGNDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRG
CGEAMLQDFKKQVEITEALQKVTREIKQMSAEKYDVSPQVVIQLRQKLEGLQMSGLPDSF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLCEKCVSEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFLGISKERVPFVLTPDFLYLMGTTGKKSSPHFLQFQDVCLRAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQ
FNWFLHLVLGIKQGVEKRSA
>A0A3N0YLB3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabarilius grahami|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSDTISAIKKMVWKNAKNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVIEFRTKMRTFCEERSQVRQMLPWYQWMECNFPCDLEPCSIVAQS
GKSRSVKKILVNVKFEGSEESFVLQQDPQDLPMVLKRNALRKKSTVFRSAKQEKPEDYTL
QVNGRMEFIYGTYPLFQFKYIFTCLHGGLTPQLTVVHHSAIIKYQEEQGGLSNQVSRSRT
QSKPPPLPLKRQNTSSLWHIQEPFYIYLVQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDINVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLVRFPNIRP
HPLYYPPIEKLNELGLNGEKVVATKEEHLKLREIVDNKNFTEIFEDEKELLWKLRGEVRQ
RYPESLSKLLLVTKWNKHEDVAQMFGLLRKWPELPALHALELLDYSFPDPHVRSFTIRCL
RKLSDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSV
SLRFGLILEAYCRGCIYHIKILMKQNEALNKMKALNDFVKSGCQKATRIQTTEDMKVCIK
QDTYLEALSDVVSPLNPSIMLCELCADKCKFMDSKMKPLWLMYKDKYDTVGIIFKNGDDL
RQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCMSTGNKTGLIEVVKNSDTIANIQRNNSNS
AATAAFNKDALLNWLKSKNPGEKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRET
GQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAY
KILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKELIQQRRVYALESLQRCRLSGCDPGTGRLLIHNTALKYNKNDRILDQESLHILL
RDSGSLNSREMVPLFYGRGAGAAHGPFNLCVPKGDHQLPLSYKLRHGLRPPAKPSFNTLL
FLLLLLGSPAPRCRLASPYPLSFLSVRHNTGWVYALQACSYMIKAGIQA
>A0A8B9SJA6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
NFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEDIDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDVCSPFKITLLKGNKLNTEENAKVHVRAGIFHGTELLC
KTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLRNGEFVLHSWSSFPDELEEMLNPMGTVQTNPYI
ENATALHIKFQEYSKHPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFFVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSIQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7N6FLZ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPGKYGMQGEWEKEGDHEIMMDFLLPTGIFLKFPVSRNDTIKTIKRMVWKNARSEALFT
ALGDPDAYVFTCINHTAEREELEEESRRISDVQPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEVQKNHEVNEFRTKMRVFCEEKAQERQRLPWHQWMEYSFPCDLEPCCSPQCG
NTEFELCVLMRSALKKKATVFRSVRQEPEDYTLQVNGRWEFIYGNHPLCQFKYIFSCLRN
GQNPHLIMVHHSTISKYQEEQGRMCNQVYKSCSLSRPPPLPLKKVRGQRTVSACVFPLQL
VVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQKLEFDINVADLPRMGRLCFALYAVIEKA
KKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVER
NPNVDSAAGLLIRFANIRPYPLYYPPLDKVLVLKTDVERNGDATTGTKEEVSNSFVKLKE
IMDNKNYTEFFEDEKELLWKLRAEVRSSYPESLSKLLLITKWNKREDVVQMVSLLRNWPD
LPAIHALELLDYSFPDPAVRSFTIRCLRNLSDDELLQYLIQLVQVLKYESYLDCDLTTFL
LERALSNRRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIRLLTKQNEALAKMK
SLSDFVKSGSQKMTVEDLKLCIRQESYLEALSDLLSPLNPSIILSGIWLVADKCRFMDSK
MKPLWLMYKNPGTQGDMVGIIFKNGDDLRQDMLTIQMIQLMENLWKKEGLDLRMIPYGCL
STGNKTGLIEVVKNSDTIANIQRNCSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEVFT
LSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTY
DFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQ
YLKDSLCLGKSDDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A7K7ZIW9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Melanocharis versteri|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGSIKQVLWKQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRSKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGRTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLDFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K8INQ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chaetorhynchus papuensis|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQQVLWKHAQYEPLF
HMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISL
LIGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLG
TGSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDY
TLQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKA
ASKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVS
SSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIA
WVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVA
AHPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRY
DIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFA
INSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMH
VPAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMH
MCMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGII
FKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANI
QLNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFR
GYCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRL
KFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6J2V8Z2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chanos chanos|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLISIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELMKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPDLPQH
IFSKLDKGRLIVTIWVIVSPSNSKQKYTLKITHDCLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCITVGRLPHLMLVSKDSLYSQLPGN
SFIAPSYSRRTPQPSPCPGGGDPSAPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDTLVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
CFNQTVIFPDEQQIEEHANWTISRELGYNYCLGLSSRLACDSTVSQVDAEQLRTLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLRDWPLMQPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRGCGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIKDKNKGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A8C6DMM9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Moschus moschiferus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRIPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPTTQVQKPR
TKPPPIPMKKPCSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>H2YGA9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ciona savignyi|TrEMBL
MYAYEEESIYDEWGYHNSLNVSVDFFLPTGIYIPLDIPRNYTIKQVKHVLWEEAIHYPLF
SKLLNPESYIFTYITSFGLTEEIVDELRHLSEVRIDFHWSTPLVGYQIVTMKKLMSAEIL
LNISDDNELNIDHESSSFRKDMREMAIQVSKQRDALHWKVGTIYCKPREPFCQECSSTYI
IKVGIKLFIIFKTLKTVYTIKINPGWTTDTLTREALAAWRQKTKSRLPSDNDDDYVLKGG
GKEYLVGNHPIYMFKSTVSSVHAPPILTLLHVANVRKLLPQQSQLLMKMQVDKFNFLFNN
LAPPVPEKHRPVWSLWQLDVMFKLRVIRAGNVNAAQERDKKLVIHIGLYHGSETLCPTTY
TKEPVKETAAGNEYQWDEECFFDINAVNLPRNAMLCFAVCSSKRGVGGKTKKDKKDGNQK
YIQAATPIAWVNMMVFDFKRFLKAGLYRLNCWPVNLDNLDSNNLFPRGGLMTNPDVEQAT
FIEIAMTEYQAAIMYPSLPEVLEEAARQAVVRESNLMTSAASKLHMTQLEEVIRKDRFDD
LYDDDKSLLWRLRIDCREHFPDALSKVLASANWSSYKSVAMVQAMLNSWKPLSPEHAMEL
LDSQYADEHVRDFAVKCLESLRDDELQQYLMQLVQVLKFDSYLSSSLVRFILRRAWNNRK
IGHFLFWHLKSEISQKTLNLRFSLILEAYLYGNLPHMKTLCKQHEALNKMRTLNDRVSFS
PKDIKVRARQALKDTANQDSFREALTSVECPLEPNIDMQELLVDKCKVMNSKMRPLWLVF
KNSDMQDGSIAVIYKNGDDLRQDMLTLQTISIMDVLWKSEGLDLRMIPYGCLATGEGTGM
IEVVTHANTIANIQKTRGGKMAAFRHQTLIEWLEQNNTTKSEFDQAIENFTYSCAGYCVA
TFVLGVGDRHSDNIMVTEKGQLFHIDFGHILGNFKTKFGIKRERVPFVLAHDFVHVINKG
KNNNKADFDKFRKLCDNAFCILRRKGYLFITLFALMVHSGLPELNSLDHLEYLRETLALH
LTEQKALQQFRSKFNKALTDAWATSVNWFFHNVTRDNT
>A0A672QVT3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPAKTDQLDLWAESGLNGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLGTGSLE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHSPEEDIGTRSDY
VLRVSGRFEFLFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKTMFEKEISTIGSVLAR
KTSNPPLPLPPKKRPPTVSTLSLHTCVWKVHSLFRINLVKGNKVNAEDAIQVRAGLFHGT
ELLCKPAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTH
LNKYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQT
NPYTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEI
MERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKL
SPRDALELLDFNYPDQYVREFAVICLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLL
ERAQSSRKIGHFLFWYLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKA
VSELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLQSPLNPNILLAGVHVERCKYM
DSKMKPLWIVYNNKLLGGDTVSIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPY
GCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFI
LTHDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVK
DIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIDYLYATSPF
>A0A672KV85|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDVSGPHSRALYVYPPNVESSPELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTETDIEQLRQLSNRDPL
SEITEQEKDFLWRHRQYCVNIPEVLPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERCVCACWKLFRDIGNDMVCVLSMHVTHYTITAQVS
>G3U646|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Loxodonta africana|TrEMBL
MDLENAEPPVVLRADNFRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRNSKTRETVLLH
VAGHGNVEQVKAQVWLRALETSVAADFYHRFGPDHFLLLYQKKGQWYEIYDRHQVVQTLD
CLRYWKMLHRSPGQIHVVQRKALSVETVAFQQQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLSKKIANNCIYIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLSHRRTSPKPFTEEVLWNVWLEFGIKI
KDLPRGALLNLQIYCGKAPALSGKASAETPGSEPKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKESSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKYPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVRELALWEHFVLIYYI
NNVTQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQRVTIDIKSVSVEKYDVSSQVISQLKQKLEDLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSKETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPLEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGISKERVPFVLTPDFLFVMGTSGRKTSPHFQKFQDVCARAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A556V6Z8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bagarius yarrelli|TrEMBL
MKAFTSNSPTAMDHLRLEFVLPTTNKTTKNPDILQLDVIGNWTVEQVKAQLFLKAITTNL
CPEFYQKYSPDHFILLYKKKGSWCEIYDKHQVFQTLDCIHYWKALKKEVGKIYLVLRPQP
SEESIQYQKFLNHLIGYDVTDVSNVHDDELEFTRRKLLTTRKIELAERDPRLYSMDPWIT
TKPLPDYMLSKITNSHILIVIHKDTSSQTIKVSIDDTPFHILQSFFIKTVNKRALLGIPE
DVKESDFVLRVCGREEYLFGNYPIKDFHWIRQCLKNGEEIHLVLESPPDPEQDVVQKEDW
SQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRKFRVKILGIDIPVLPCNSELMVFV
EASIFHGQQLLAQERTSLKPFTEEVLWNTWLNFNIKIKDLPKGARLNLQVSCGKAQTQSS
KDSVSQDCKNKSRLLYYVNLLVVDHRSLLRQGEFILHMWKMPEKNEDNSSVNADKLTSAT
NPDKTHSMAIAVLLDKYCYPVALPKSRDSRDASEIDGERGKREMPNHLRKQFDQIVATDP
LHPLSVEDKELLWHFRQECIRHPSAYPKFLGSVKWGKQEDVMATHHLLEKSTTWDRSPLD
VGLAMQLLNCHFSDANVRTMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALSRFLLK
RALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGNGMLQDFRKQVEITEALQ
KVTREVKAISAEKYDISAQVVFQLRQKLESLQVQGLPESFKVPYDPGLRAGSLVIEQCKV
MASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLS
LLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDEILNQWLQDKCVNEDKYQQ
AVERFVYSCAGYCVATYVLGIGDRHNDNIMVTESGNLFHIDFGHILGNYKSFLGITKERV
PFVLTPDFLYVMGTTGKKTSSNFLLFQNICVKAYLALRHHTNLLIILFSMMLMTGMPQLT
SKEDIEYIREALTVGCTEDVAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVEKRSA
>A0A5E4D6X2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Marmota monax|TrEMBL
MLWDQAQNEPLFHMLSDPEAYVFTCVNQTAEQQELEDEQQRLCDVRPFLPMLHLVTRQGD
RMEKLINSQISLLIGKGLHEFDCLQDPEVNDFRTKMRQFSEEAAARRQQLAWEAWEAAPP
AAHGLLCPWGPSTDKTLQCPRPPNFSSLTGITWHLPGMQACKGCSQASHQESFIIQVSTK
DVPLALMACALQKKAKVYQHLTMEKPEDYVLQVNGRHEYLYGSYLLCQFKYICSCLHSGL
TPHLTMVHSSSILAMRDEQSKPAPQVKKPHTKPPPIPMKKPSSVSLWSLGQPFCIELIQG
SKINADEQMKLVVQAGLFHGNEMLCKTMSSLEVSVCSEPMWKQHLEFDINICDLPRMARL
CFALYAVMEKAKKARSSMKKSKKVAGTLRTGVLGEPGDPSLSARPSLAP
>A0A7N8Y7T7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSRNDTIKVIKKLVWKNARSEALFT
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTRMRQFCEEKSQERQMLPWQQWMEYSFPCDLEPCCSLPST
KSRNTKKIFINIKFEACDESFMLQQDPQDLPVALMKSALKKKATVFRSVRLEPEDYTLQV
NGSWDFIYGKHPLRQFKYIFSCLRNGQNPHLIMVHRSTISKHQEEQERMCNQVYKSRSQS
RPPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSS
EVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWV
NTMVFDYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFPNIRPH
PLYYPPLEKRNDDTVTATKEEHQKLKEIMDNKNYTEFFEDEKELLWKLRYEVCSLYPESL
SKLLLITKWNKREDVVQMVGLLRNWPDLPAIHALELLDYSFPDPAVRFFTIRCLKKLSDN
ELLQYLIQLVQVLKYESYLDCDLTTFLLERALANRRIGHFLFWYLRSEIHVASVSLRFGL
ILEAYCRGNIHHIKLLTKQNEALGKMKILSDIVKSGSQKMTVDDLKLCIRQESYLEALSD
LLSPLNPSIILCILSSVCGIIFMDSKMKPLWLMYGNPWAQGEMVGIIFKNGDDLRQDMLT
LQMIQLMENLWKKEGLDLRMSPYGCLSTGNKMGLIEAVKNSDTIANIQRNSSNSAATAAF
NKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRENGQLFHI
DFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRN
GMLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTK
VNWMMHSLAKDNRP
>A0A672GY75|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salarias fasciatus|TrEMBL
MTLSHCFTVIFAMPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQLDVPREATI
QHIKLLLWKQAQSFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLV
TRNCGRAERLLDSKIGVLIGKGLHELDAINDQEVKDFRIKMFRLSEERMQRVQMMTCTEW
LQACFSPQLEPPLLLLQKSDLTARLSPFCSLVLQDSASLKVPSCYTPAELMEQALRKWVT
THGPEEEAWGGQHVLRVSHCLEFLCGDHPLIQYKYIRSCLQAKEPPHLTLVHTNTVKAMF
DKEMTAIGAVVSRRSSNPPLPLPPKRRTCVWDVSSPFKIVLVKGSKVNAEETAKVQVRAG
LFHGTELLCKPAVSSESSGQRASSEHTWRDNTLEFDISVCDLPRMTRLCFAIYAVMDKVK
KQKSTKNSHINKYQTIRKAGKVHYPIAWVNTMVFDFKGQLKTGDITLHCWSSFPDELEEM
LNPIGTIQTNPYTENATALHIHFPEYSSHPIIFPPFDKILEKAAEIVGASDCVSGARGGK
KFYIELKEIMERDPLSQLCENEKDLIWTLRHDCWENFPQSLPKLLLSVKWSKHEDMAQLQ
ALLQIWPKLSPRDALELLDFNYPDQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYY
DCALTHFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQ
VEALSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPNV
QLSGINVERCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLL
WKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLK
ERNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFK
SKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLVLRKNGNLFITLFAL
MLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAK
DNRS
>A0A673TM56|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Suricata suricatta|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSVLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSASREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7L3PY87|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cettia cetti|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTNNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSPESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIPSD
TQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVAKKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A673T0D1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Suricata suricatta|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLLERPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMREEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSAPDEKGELLNPAGTVRSNPNTESAAALVICLPEVSP
YPVYYPALDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPDLPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMR
QETYMEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWLMYSNEEAGGDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGYC
ERAYTILRRHGPLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A672I641|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salarias fasciatus|TrEMBL
MPPGKYGMQEEWEKEGEVVMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFSGL
GDPDAYVFTCINQTAEREELEEESRRVSDVRPFMCVLRLVAREGDRVEKLTNAQISLLIG
KGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERQSLPWHQWMEYSFPCDLEPCCSPPGSKT
KNTKKIFVNVKFEASDESFMLQQDPQDLPMALMRSALKKKATVFRSVRQEPEDYTLQVNG
RWEFIYGRHPLCQFKYIFSCLRNCQNPHLTMVHHSTISKYQEEQGRMCSQVYKTRSLSRP
PPLPLKKVRLPNHTSCPGLICVCVCSSPSQLVVQAGLFHGSELLCKVVTSSEVTVCSEPL
WDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKRAVNYQSIKNFQSDCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVDLLNPMGTVEKNPNVDSAAGLLIRYPNIRPHPLY
YPPLEKNVRLKEIMDNKNYTEFFEDEKELLWKLRAEVRDRFPESLSKLLLITKWNKREDV
VQMVSLLKKWPDLPAIHALELLDYSFPDPAVRSFTIRCLRKLSDGELLQYLIQLVQVLKY
ESYLDCDLTTFLLERALSNKRIGHFLFWHLRSEIHVASVGLRFGLILEAYCRGNIHHIKL
LTKQVINEALGKMKALSDIVKSGSQKMTAEDLKLCIRQESYLEALSDLLSPLNPSVVLAE
ICADKCRFMDSKMKPLWLMYRNPLAQGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKE
GLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNP
EDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLG
INRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAA
GLPELTSFKDIQYLKDSLALGKSDEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A3B5QGP0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xiphophorus maculatus|TrEMBL
MPPGKYGTQEEWEQDGDQEIFMDFLLPTGIFLKFPVSRNDTIRNIKKMVWKNASREALFC
GLRDPDLYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNTQISLL
IGKGLHEFEAQKNHEVDEFRTKMRTFCEEKSLERQNLPWQRWMEYSFPCELEPCSSPAAG
GSSKSKHGKKLFVNVKFESSDESFMLQQDSQDLPVALMKSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGQHPLGQFKYIFSCLRNGQNPQLTMVHHCTISKYQEDQGRVCSQMYKTR
SLSRPPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKMM
TSSEVTVCSEPSWDQRLEFDINVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPI
AWVNTMLFDYKDQLKTGEFLLSMWPSVPDDKSDLLNPMGTVQRNPNVDSAAGLLIRFPNI
RPHPLYYPPLDKTIEPEMNGNTVFPSKDEYLKLKEIMDNKNYTEFFEDEKELLWKLRAEV
RDYFPECLSKLLLITKWNKREDVAQMVGLLKSWPELPAIHALELLDYSFPDPAVRSFTIR
CLKKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLKSEIHVA
SVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDIVKTGSQKMTVDDLKLCIRQE
SYLEALSDLLSPLNPSVILFEICTDKCRFMDSKMKPLWLMYKNPLEQADMVGIIFKNGDD
LRQDMLTLQMIRLMENLWKKEGLDLRMIPYGCLSTGNKTGLIEVVKSSDTIANIQRNSSN
SAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERA
YKILCRNGTLFVNLFAMMKAAGLPELSSSKDIQYLKDSLALGKSEDEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A8D0PMC3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MLVGFISTPPASRFSVAMPVLEEGLTSDCPSQVLWHRAQYEPLFHMLSDPEAYVFTCVNQ
TAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHEFDSLHDPE
VNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGPGTLRVPNRALLVNVK
FEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYTLQVNGKHEYLYGSYP
LCQFQVRARGLPVTAGVVGSTELYRKPAKPPPTPPAMTTGLVTGASLLRIPLLQWPCFSV
HLHTQPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSV
CSDPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLML
FDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAPHPVYY
PSLDKVSEEPLDLPKCPGPTLPRNLELREILERRGSGELYEHEKDLVWKMRHEVQEHFPE
ALARLLLVTKWNRHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLT
DDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRYSEMHVPSVALR
FGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQET
YLEALSHLQSPLDPSLAEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNGDDLRQDML
TLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAA
FNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFH
IDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYAILRR
HGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKT
KVNWLAHNVSKDNRQ
>A0A6P8T547|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gymnodraco acuticeps|TrEMBL
MPPAMTDLLDIWAAHSPLAGHALDHISVDFLLPTGIYIQLDVPREATIQHIKLLLWKQAQ
SFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAETLLD
SKIGVLIGKGLHELDAMNDQEVKDFRSKMFRLSEERMQQVQMMSCNEWLQACFSPQLEPP
AGAAAIAEPVDLKIIIHLDQSQDSASLKVSSSCTPPELIELAVRKWLTTHGPEEEAWRGQ
HVLRVSHCLEFLCGQQPLIQYKQVQTCVWDVATPFKIVLVNGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESSGRSDHTWKDSTLEFDLSVCDLPRMTRLCFAIYAVMDKVKKQKST
KNSHSNKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHSIIFPPFDKILEKAAEIAGASDSVPMGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLQRAQGNRKIGHFLFWHLRSEIHMPAVCVQFALMLEAYCRGSIPHIEVLKKQVEALS
KLKSVNELIKLGTLKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNILLSGI
NVERCRYMDSKMKPLWIVYNNKLMGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAN
LDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNTG
DALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGYTEKFASFRKYCEEAYLVLRKNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDDDALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>M3ZR32|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xiphophorus maculatus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHDLFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGSHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMSKESLYSQLPME
NFTMPSYARRISTATPYMNGETATKCLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYVTEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMSMIEDHANWNISRELGFNYSHPGLSNRLARDKPLTESDNEQLRQVCNRDPL
SEITEQEKDFLWSHRHYCINIPDILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHALHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A6B0R6J2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASMSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7L1D6R6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Serilophus lunatus|TrEMBL
MELEDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYQAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSVDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNDDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSAKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGSSTKTNLQSHESSNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6G0IPX1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Larimichthys crocea|TrEMBL
MPPGKYGMQEEWEKEGDQGIVMDFLLPTGIFLKFPVSRNDTIKSIKKMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEESRRICDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERQMLHWQQWMEYSFPCDLEPCCSLPVC
ASAKSKNSKIFINVKFEASDESFMLQQDPQDFPVALMKSALKKKATVFRSVRQEPEDYTL
QVNGTWEFIYGKHPMCQFKYIFSCLRNGQNPHLTMVHHSTISKYQEEQGRMCSQAYKSRS
LSRPPPLPSEEVCFVQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLC
KVVTSSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKAD
CPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRF
HNIRQHPLYYPPLDKISDVEKNGDAPFATKEEYMKLKEIMDNKNYTEFFEDEKELLWKLR
AEVRNHYPESLSKLLLITKWNKREDVVQMVSLLRNWPDLPGIHALELLDYSFPDPTVRSF
TIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEI
HVASVSLRFGLILEAYCRGNICHIKLLTKQNEALGKMKALNLLSPLNPSIILAEICADKC
RFMDSKMKPLWLLYKNPLAQGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRM
IPSNSAATAAFNKDALLNWLKSKNPEEKLDKAIEEFTLSCAGYCVATYVLGIGDRHNDNI
MIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRGY
CERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKF
NEALRESWKTKSVRRSSADWRDVTPEQDALLQQHTIQTEHRRKEKLDQEGATGAGGMNRE
EAPGKSPEDMYIQQKVRVLLMLKKMGSNLTPSEEAFLRNYAGVVHSQMSQLPQHNIDQGA
EDVVMAFSRSETEDRRQ
>A0A6G0IQV8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Larimichthys crocea|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTEELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYTLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8B9WUA2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus grunniens|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASMSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7L3RDH8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cepphus grylle|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6P5D206|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos indicus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKPLILTLTWLP
RLSGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPFLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLSSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLXLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A172ZPS6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Haliotis diversicolor|TrEMBL
MAMAWTYFDVAGRPMDGSPQLPSIKTPEYMIDRDRPNNYIRDVDFLFPNGILLPFSVRDY
FSPPMDQIKTSIIWREVHNYRPLADNDIRAEKNSYNFFFINRMGESPEEVKMDESQNLEA
WKLQPFLAMFQKLVENKEEDDRSTKTLDKIKIDHLIGRGIQKESQESFQTKVAEINHYLK
QKMSEMAREPGITILRRDPKSPMENQFQWKYPVRLRSHDFIPSQPGVESRIVNIGAIVVD
IGFGERAKMCYKLTTRVSQNNGKTPEDAVKMELPLNKKRTTLNYGTPLEDSKLYIALKVI
GQAEEYIYGNKFPLQQYKYVYQCLVKNTAPQFLLVARESVIDPKPAVPPRKGSIANYSQI
PSDRRGDDICVWDLKEGYYLTVRGIGKVQLPDGAKVKLFMGLYHGSEALCSIKTTDEMVV
QEGVCNMKLDVAFDIPACDIPQMARVCFTLCATGKKKDQTAVAWVNVAVFDFRSRLTRGD
RNLPMWPWTDEMQTEEFLYPIGSVTPNAQGNEATTLLIKFPDFNMKNNIRYPAFDKVLEC
AAKHMEPSGAPGSAMMKVSKSHLEQLMMIVQRDSLSPLFEQDKELLWMMRYECCHKFPHA
LPKVLSSVKWNSHIDVAKMIAVLQTWPKLDVDFALQLLDFNYPDKNIRKFAVSCLDNKDT
FSDDELSRYLLQLVQALKYETHLCCPLVEFLLTRALGNQHIGHQLFWLLKSEMYNPYVSV
QYRLILEVYLVVSGEHMMALHKQQEALGKLCIVNGLIKSERYNMGDQKSHEQAKKDMQAV
LQQKTYQDILSNLGSPLSPLFRLKSLAIDKCKFMKSKKRPLWLVWKDDLGQDVSLIYKNG
DDLRQDMLTLQMLEIMDNIWQSEGLDLRMNVYRCLATGQEQGVIEAVGQSQTIANIQKWF
NRGAFDKKAVFEWLKHHHKTPESLDEAVEEFILSCAGYCVATYVLGIGDRHNDNIMLKQS
GQLFHIDFGHFLGNFKSKFGVKRERVPFVLTTHFVYVIQKGKSNNSENFKRFQSTCEKAY
LILRKKAPLLFSLFLMMLSSGIPQLTCPKDVNYLRETLVPHLSEIDARAHLRSRFNQVLK
GSWKASLYFWFHIQLNQ
>A0A8I3PX85|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNDFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPNDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKNI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKSRGGKKFLAVLKEILDRDPLSQLCENEMDL
IWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQ
YVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWH
LRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNKAK
GKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGE
DSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTS
ETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGI
GDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTE
KFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEA
LKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A667GMF7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lynx canadensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEETP
CLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQL
RAICTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWP
PIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVR
FLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEK
LINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRI
MSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDL
RMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYD
AAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRER
VPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMP
ELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8D2MCA5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zonotrichia albicollis|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQVWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIVIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKYKTQLLYYVNLLLIDHRFLLRC
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A2I4CMJ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Austrofundulus limnaeus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHDLFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSNSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRMPNLMLMSKDSLYCQLPMD
NFTMPSYARRISTATPYMNGETATKCLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMSIIEEHANWNISRELGFNYGHTGLSNRLARDNPLTESDNEQLRQVCNKDPL
SEITEQEKDFLWSHRYHCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMMREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDEAQKVQMKFLVEQMKRPAYTDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHALHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A667X735|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDFVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPID
TFVMPSYSRRISTATAYMNGEAAAKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWSVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMSAIEDHANWTISRELGFNYNLSGQSNRVARDHALTESDKEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMDIPEILPKILLAVKWNSRDEVAQMYFLLKDWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8J8XJE7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca fascicularis|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K4IT15|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geococcyx californianus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFVLPTSNKLTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGVSTKTNLQSHESPNSDSKCKTQLLYYVNILLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVR
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLDDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMDIKSVSAEKYDVTSQ
>A0A151MP29|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alligator mississippiensis|TrEMBL
MPPTVLLECLLPNGMLVPLESPREASLLSVKRRLFREARKYPLPHLLRDAACYVFVGVTQ
DAAREEFFDEARRLCDLRLFRPFLQVVEPAGDRDEKMLNREIGLAVGTPVRELEASRDPE
VRDFRRNVLNVCREAAERRGADAPRSRALYAWPPRVHASPELPRPLYDKLDEGQMVVAVW
VVASLNNKQKYPVKISHDCVPEHAIAEAVRAQTRSASLSPEQLKRRVLKYQDKYVLKVCG
CDEYLLERYPLSQYKHIRNCIMVGLVPNLMLMSKESLYARLPSDSFTIPSCPRGVSTPTP
YTNAEVSAKSLWSINSGLRIRIFCATYVNVNTRDVDKIYVRTGIYHGGEPLCDNNNEIIF
KNGDDLRQDMLTLQIIRIMENIWQKEGLDLRLLPYGCLSIGDRVGLIEVVRSSYTIMQIQ
CKGGLKGALQFSSHTLHQWLKDKNQGAAYDAAIDLFTCSCAGYCVATFILGIGDRHNSNI
MVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLLVISKGNQDCTKTREFERFQ
EMCYKAYLAIRQQANLFINLFSMMLGSGIPELQSFDDIAYVRKTLALDRTEQEALDYFTK
QMNDAHYGGWTTKMDWVFHTIKQHALN
>A0A7K4PGL6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Melospiza melodia|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQVWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIVIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKYKTQLLYYVNLLLIDHRFLLRC
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>G5C1G3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Heterocephalus glaber|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYRRICFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRD
IDKIYVRTGICHGGEPLCDNVNTQRVPCSNPRWNEWLNYDMYIPDLPRAARLCLSICSVK
GRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKSN
RLARDNELRENDKEQLRAICTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWN
SRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQL
VQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRAC
GMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPL
NPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQ
IIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSH
TLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFG
HFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHA
NLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKM
DWIFHTIKQHALN
>A0A7L2XAY8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Erpornis zantholeuca|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLSLPVSCNASLGSIKQELWHHAQHEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGT
GSLQIPKNIFVNVKFQSGGESFTFQICPEVFPITLMSYAIKKQATVFRHETVQKPEDYTL
QVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQNNCISSPPKAAT
KPPPLPKKKPNCGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSS
EVSVCSEPVWKQRLDFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWV
NVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAH
PVYYPSFEQLLELGRNGEQPRAAPEDSDEKLQLKEILERRSHTELYEHEKDLVWKMRYDI
RDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAIN
SLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVP
AVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMC
MKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFK
NGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQL
NKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGY
CERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKF
NEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L3FGX3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zapornia atra|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKQGKAPEIMLLE
IAGNCTVEQMKAQIWMHAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKVKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHTVTMEIKSVSAEKYDVTSQVIAQLRQKLERLQSS
NLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A663LSD1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Athene cunicularia|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCISSPPRMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K4ZQH7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Centropus unirufus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSTLSSMELISIEFILPTSNKHTKVPEMLLLE
IAGNCTVEQMKAQIWMRAIEISQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQRQQPSEAVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKISNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGVSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPRAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLDDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3B4EYY7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pundamilia nyererei|TrEMBL
MAPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLTTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYSNTPHCAGTKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLKMCVQEYQGKYILKV
CGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMDFFTMPSYARRISTA
TPYMNGETATKNLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGIYHGGEQLCDNVNTL
RVPCSNPRLWNEWLTYDMYIPEVPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYT
HTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHYSSAVKFPDMSTIE
DHANWNISRELGFNYCHTGLSNRLARDNPLTDGDNEQLRQVCNRDPLSEITEQEKDFLWR
HRHDCINMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNFPDPMVRE
FAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKS
EMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLKQEKKDEAQKVQMK
FLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWENPDMMSELL
FQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRN
SHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRSCAGYCVATFILGI
GDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTK
TREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQ
EALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A851AQQ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sula dactylatra|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAVKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAVPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEERGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C6K1Q2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Melopsittacus undulatus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GPFHIPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKTA
AKPPPLPKKKPNYGSLWSLEQSFYIQLVQGSKVNADEGMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWQQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQPLCTNSMGVHKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALA
KLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAVNSLKKLTDHD
VFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLI
LEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMMHVCMKQETYLEA
LSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDM
LTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMQSDTIANIQLNKSNMVATA
AFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLF
HIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILR
RHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWK
TKVNWLAHNVSKNNRQ
>A0A8C5NP11|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Junco hyemalis|TrEMBL
MPPGIYCPTEFWSKGENQSIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPNKNIFVNIRFQSGGESFMFQISPWEFPITLMSYAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPYYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLIITKWNRHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A5F9D1T9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryctolagus cuniculus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQLLW
KQVHNYPMFNLLMEIDAYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEEKIQSLVGLSWIDWLKQTYPPEH
DPSSLENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
ASPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRITSHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASNDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKQVLPTLLLSCMSLD
>A0A3Q2QEQ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fundulus heteroclitus|TrEMBL
MDRQQFQVSDEERDVAREESRRRRRKKAITSSSSASMDQVNVEFVLPTAARGGSGPDSLL
LEVPGNWTVEQVKAQVWMKAVSLSLCPDFYQRFSPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLAPRPQQSEESQQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDSKLYSMDPWVTWKPVPEHLLSKVNNGYILVVIHVSTSSQTIKVSIE
DTPSQVLGNFFAKTANKRVLLGIPENMSEEDFVLRVCGREEYLYGERALQSFNWIRQSLK
SGEEIHLVLETPPDPELDHVQREDWAQVDDCTGVTGTHEQLTIAEKDHERVFTISMWDCN
RKFRVKVLGIDIPTLPKLPEFTVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIRDLPKGARLNLQVICGKQPQTANSKGAKTKNRLLYYVNLLLIDHRSLLRQGEFILHMW
KMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSREVGRDCVVGSE
EGDAGERGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGS
VRWGKQEDVLATHRLLERSYAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDD
VLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAV
LLEAYLRGCGENMLQDFRKQVMILEKVNLRQKLETLQSSGLPESFRVPYDPGLRAGALLI
EQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETE
SLDLCLLPYGCISTGNKIGMIEIVKDANTIANIQQSVVGSTGAFKDEILHQWLRDKCVSE
EKFQLAVEKFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGI
SKEWVPFVLTPDFLYVMGTSGKKISPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTG
MPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGV
EKRST
>A0A665VYL6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MCDCFHYVCVLWCVLPLAMPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDV
PREATIQHIKLLLWKQAQTLPLFPALGEMESYMFECVNQAAVHEELEDETRRLCDVRPFL
PVLKLVTRNCGRAERLLDSKIGVLIGKGLHELDAINDQEVKDFRSKMFRLSEERMQRVQK
MSFSEWLQAFVYQNNHFTFKSEEFSLLVFQDSASLKVSSSCTPTELMEQAVRKWLTTHGP
EEEAWRGQYVLRLSHCLEFLFGDHPLIQYKYIRTCMQAKESPHLTLVHNSTVKAMFDKEM
STIGAVVNRKSSNPPLPLPPKRRHPTTCVWDVSRPFKIVLVNASKVNAEETAKVQVRAGL
FHGTELLCKPAVSSESSGRSDHMWKENTLEFDISVSDLPRMTRLCFAIYAVMDKVKKQKS
TKNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDINLHCWSSFPDELEEMLNPI
GTIQTNPYTENATALYIHFPEYSSHPVVFPPFDKILEKAAEIARASDCGTMGRGGKKFHI
ELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQ
IWPKLSPRDALELLDFNYPDQYVREYAVRCLRDMSNEELSQYLLQLVQVLRYEPYYDCAL
THFLLERAQGNRKIGHFLFWHLRSEIHMPAVSIQFALILESYCRSCIPHIEILKKQVEAL
SKLKSVNELIKLGTTKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPHILLVE
RCRYMDSKMKPLWIVYNNKLMTGDNLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDL
RIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDAL
DRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRE
RVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPE
LTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7L4AM71|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phaetusa simplex|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGAIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIASPPKMA
VKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K6L1Q5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Falcunculus frontatus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNHPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A093EGT5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tauraco erythrolophus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYNQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMXXXXXXXIRK
TLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>H2SAV2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKHPISQYKYIRSCIMLGRMPNLMLMAKDSLYSQLPTD
NFVMPSYSRRISTATSYMNGEVAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYISDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSSVKYPDMNAVEDHASRTISREVGLNYTLSGQSNRAARDHILTEGDSEQLRQLTNRDPL
SEITEQEKDFLWRNRYYCMNIPEILPKILLAVKWNSRDEVAKMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECVKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A4U5VR63|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Collichthys lucidus|TrEMBL
MDGKQTPVSDEEPKVLREDTRRRRRKKAITSSFSASMDQITVEFVLPTAARSGNSPDTLQ
LEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSEESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLNKVSNNHILVVIHIGTASQTIKVSID
DPPAQVLASFFTKTANKRVLLGIPDNMCETDFVLRVCGREEYLYSDKPLQDFNWVRQCLK
NGEEIHFVLETPPDPDLDLVRKDEWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPFLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVVCGKQPQTPNSKGGSSYQDNTAGTGSHDGKTKSRLLYYVNLLLID
HRSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVL
PKSRDVGRDLGAGNEEAEGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRH
ECMRDPRAYPKLLSSVRWGKQEDVLAAHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQV
RSMAVRKLETLEDDDVLRYLLQLVQSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLR
GCGEDMLQDFRKQVEMTEALQKVTRDVKAMSADKYDVTAQGESLKFSSEKSLSCSSHSNI
IEQCKVMASKKKPLWLQFKRADSTTLSKDPIGIIFKHGDDLRQDMLILQILLIMESIWET
ESLDLCLLPYGCISTGNKIGMIEIVKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVS
EDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMG
ISKEWVPFVLTPDFLYAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGR
SEDEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A8J6FUP1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eleutherodactylus coqui|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMMVTLECLREATLVNIKHELFKEARKYPLHH
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRKNILNVCKDAVELRDANGPISRALYVYPPNVESSSELPKH
IESKLDKGQIIVVIWVIVSPNNEKQKYSLKINHDCVPEHVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKDSLYNQIPVD
TFTMPSYSRRISTATPYMNGEASAKSLWAINSNLRIKILCATYVNVNIRDIDKIYVRTGI
YHGVEPLCDNVNTQRVPCSNPRWNEWLLYDMFIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDCF
SSPVKFPDMVAIEDHANKVLEREMGYNYSHSGLTSRIARDNEVRESDKEQLKAISTRDPL
SEITEQEKEFLWSHRLYCRNTPEILPKLLLAVKWNCRDDVAQMYCLLKDWPPIRPEQAME
LLDFNYPDRIVRSFAVTCLEKYLTDDKLSQFLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDEPHKVQMKFLVEQMKRPDFMDALQGFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSEMLFLNNEIIFKNGDDLRQDMLTLQILRIMESIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRCSHTIMQIQCKGGLKGALQFNSHTLHQWLRDKNKGETYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDNGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGIQECTKTMDFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKVDWIFHTIKQRALN
>A0A5N3XJU1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Muntiacus reevesi|TrEMBL
MCFYFMMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISCIKQMLW
KQVTNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPEL
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMSRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIILVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKSDHIWNEPLEFDINTCDLPRMTRLCFAVYAVLDKVKTKKSTKTM
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRCGDITLHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPHALPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C4Z7Z8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMLLTLECLREATLITIKHELFREARKYPLHH
LLQEQTSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILSVCKDSVELRDVSGPHSRALYVYPPSVESGQELPKH
IHSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMRLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYSQLPAD
AFVMPSYSRRISTATAYMNGELAAKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRYLQHRAERLQSSMAMSLSSRHLEHCPLGWGNINLFDYT
HTLVANKMALNLWPVPRGMEDLLNPIGVTGSNPNKETPCLELEFDHFSCLVKYPEMSSVE
EHANWSVSREMGFSYNLSGQSSRMARDIALTEGDVEQLRQLSHRDPLSEITEQEKDFLWR
HRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIQPEHTMELLDCNYPDPMVRC
FAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKS
EMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLIHLTDLLKQEKKDETQKVQMR
FLVDQMKRPDYMDALQSFTSPLNPAHQLGNIRLDECRIMSSAKRPLWLNWENPDIMSELL
FQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRN
SHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNRGETYDLAVDLFTRSCAGYCVATFILGI
GDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTK
TREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKTEQ
EALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A452QLS0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus americanus|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRHSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLLDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIQI
KDLPRGALLNLQIYCSKAPAPTGKGSADTPGSEGKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLEAY
LRGCGTAMLHDFSQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQCVYRWYTQLW
HGLLTGQRALTRVNPSP
>A0A452SRA8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus americanus|TrEMBL
MPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEHEPSVLE
NLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDEVSPYDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEIIAIEAAINR
NSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHGTELLCK
TIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQ
TIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIKFPENKKQPYYYPPFDKVS
>A0A8C5AD41|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MVPKPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLANIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDEARRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFELVKDPEVQDFRRSILSVCREAMEEREAGGAPSLALYVYPPNVESSPELPQH
IYYKLDKGRLMVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKTRSMHLSAQQLR
LCVLEYQGQYILKVCGCDEYLLEKYPLSQYKVGNHLLFCQSLSNQLPASGFCIRRTPQPS
PCPGGDPTSPPRSLWAFNNLLRVRLLCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNT
QRVPCSNPRWNEWLSYDIYMADIPRSARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYK
DTMVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFCWFNQTVVFPDDQQIE
EHANWTISRELGLTYCLSVSAAEVEQLQSLCSKDPLYELSEQEKDFLWRHRHYCVNIPES
LPKLLLSVKWNSRDEVSQMYCLLKDWPLMQPESALELLDCNFPEPVVREFALRCLLQGLS
DDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFFWHLKSEMHNKTVSRRF
GLLLEAFCRSCGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQKTQMKFLVEHMSRPDY
MDALQGFISPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFTNNQVIFKNG
DDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSYTIMQIQCKA
GLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTRSCAGYCVATFILGIGDRHNSNIMVK
DNGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLLVISKGSQECTKTKEFDRFQEMC
YKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKTQQEALEYFTKQMN
DAHHGGWSTKMDWIFHTIRHMPNEH
>A0A8C5FP93|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
ILLKQLVWRRASSEPLFNALGDPASYVFVCISSAAERLELEAEHRRLADVRPFACFLQLV
AREGDRAEKLANAQISLLIGKGINEFEAQKNHEVSEFRARLRAFCEEKALQQQALPWFQW
MECNFPCDLEPCRALPSRGGGAKAPKKIFINIQFEGSDVSPFMLQQDPQEPPLALIRSAL
KKKATVFRWVRQEAEDYTLRVNGRWDFLYGDHPMCQFKYIFSCLRDGQNPQLTMVYHSTI
RAYQEDQGSAWRQGSKSSTSASKPPPLPLKKVGRRGGLCLSLSPSLSVCLSVCLSLVVQA
GLFHGSELLCKLVTSSEVAVGSDPVWNQRLEFDINVADLPRMSRLCIALYAVVEKAKKPR
GTKKKSKRADCPIAWVNTMVFDYKDQLKTGEFLLSMWPSIPDDKSELLNPMGTVEKNTNV
DSAAALLIHFPSVRPQPLYYPPHDKVTGGGGSRAPHRSSVDLLKEIMDNKNHTEFFEDEK
ELLWKLRGAVQSLYPESLSKLLVITKWNKREDVAQMVGLLRAWPELSGLHALELLDYSFP
DPSVRAFTVKCLKKLGDRELMQYLIQLVQVLKYESYLDCDLTSFLLERALSNKRIGHFLF
WHLRSEMHVSSVSLRFGLILEAYCRGNIHHIRSLTKQNEALGKLKALSDIVKSGSQKMSA
DDLKLCIKQDSYMEALSDLLSPLNPSIILSEICVEKCKYMDSKMKPLWLMYKNQWVPGDL
MGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDT
IANIQRDNSNSAATAAFNKDALLNWLKSKNPEHKLEQAIEEFTLSCAGYCVATYVLGIGD
RHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKF
ERFRDYCERAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKTEEEALK
SFKVKFNEALRESWKTKVNWMMHSLAKDKRP
>A0A8C2ATQ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLWLAEHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLI
TKWNKHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLSDDELFQYL
LQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYC
RGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVV
SPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQDMLTLQMIQL
MDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALL
NWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMISETGQLFHIDFGHFL
GNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVN
LFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMH
TFAKDNR
>A0A8C1ZYU9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWVESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQNIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKRISEEKMQCMQLMSWGEWLRSCYSMTLEAGSLE
NLIDKHEGVIKITMHYDQSQDTSSLKVSLHCTVTELMDLALKKWQTTHVPEEDIGFRSDY
VLRVSRKLEFLFEDHHLNQCKYIRDCLLTNESPHLTLVHCDVVKAMFEKEISTIGSVLAW
KTSNPPLPLPPKKRLPTQLHTCVWKVHSLFRIHLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATELHISFPEYSTQPVVFPAFDKEGSSSSDIGRGGKKFYIELKEIMERDPLSQLCE
NEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDF
NYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGH
FLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFGTIK
TKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGVNVERCKYMDSKMKPLWIVY
NNKLLGGDTVDIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGL
IEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCV
ATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQ
GKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLAL
GKTDEEALKQFRQKFXINKSFTILSASPNIKC
>A0A7K9A2G1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Grallaria varia|TrEMBL
MELGDHEQPVVLREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHGGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKASVQSHESSNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
TPGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C1IHI3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MEHQASDDEPPVVRREENKRRRRKMKAFTSTSAVSTDHIAVEFVLPTTNKNSKYPDTLHL
DVTGNWTVEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVIRQQPNEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDPKLYSMDPWITPKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAISDFHWIRQCLKN
GEEIHLVLEHPPDPELDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKENECKNKTRLLYYVNLLMVDHRSLLRQGEFILHMW
KMPEKKAVAITHCLLERSTVWDRKSHDVGLALQLLDCHFSDENVRTLAVRKLETLEDDDV
LRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVI
LEAYLRGCGEAMLQDLRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQT
SGLPDSFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSRDTIGIIFKDGD
DLRQDMLILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTV
GNTGAFKDEILSQWLSEKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITE
TGNLFHIDFGHILGNYKSFMGISKERVPFVLTPDFLYVMCTTGKKSSPYFLQFQNVCLKA
YLALRHHTNLLIILFSMMLMTGMPQLSSKEDIEYIREALTVGRSEDEAKQHFLDQIEICR
DKGWTVQFNWFLHLVLGIKQGVEKRSA
>A0A8C1FRR1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVI
SNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKTLILTDGTVFFQHMKLREIDEKELLWKLREEVRQRYPESLPKLLLITKWN
KHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLSDDELFQYLLQLV
QVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSI
FHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLN
PSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQDMLTLQMIQLMDVL
WKTEGLDLRICRTWSTFSEEQCSVQLFRTNKELMNNYHKTERQSWIIQVTTHSIKNQGFP
NF
>A0A094LLF6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podiceps cristatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSCAGLSNRIARDNELRETDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C2UTR0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chinchilla lanigera|TrEMBL
MPPAMADTLDIWAVDSQLASDGTIPVDFLLPTGIYIQLEVPREATISFIKQLLWKQVHNY
PMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRRKMRKFSEEKIQSLVGLSWIDWLKQTYPPEHDPSILE
NLQDKLYGGKLIVAVHFENSQDVFSFHVSPNMNPIKVNELAIQKRLTIHGKEEEASPGDY
VLQVIGRIEYVFGDYPLIQFQYIRNCVVNRALPHFVLVECCKIKKMYEQEMIAIEAAINR
NSSSFPLPLPPKKTRVISHVWDNNKPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TVISSEISGKNDHIWNETLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQ
TIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTE
NATDLHIKFPENKKQPCYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVDCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALA
NRRIGQFLFWHLSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCIILSEL
YIEKCKYMDSKMKPLWLVYTNKVFGEDSVGVIFKNGDDLRQDMLTLQILRLMDSLWKEAG
LDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSG
DDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDEEALKQFKQKFDEALRESWTTKVNWMAHTVRRDYRS
>A0A670J7C0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podarcis muralis|TrEMBL
LYRSRMPPGIACPVEFWSKEANQSIQVDFLLPTGIYLTLSISCNASLNTIKQMVWHHAQF
EPLFHMLSGPESYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLINS
QISLLIGKGLHEFDALSDPEVNDFRTKMHQFCEERVTRRQQLSWKAWMEYSFPVQLEPSS
SSLGRKSPLQVPNKNIFVNVKFESGGVNPQESFTFQISPKEFPVTLMSYAVKKQATIFRH
QRMNSPEEYALQVNGKCEYLYGNYPLYQFQYIRDCLHRGLLPHLTMVHSTSIMALWEEQT
NGITHPSKASPKPPPVPKKKVSCVGWLCSPLSFISLSQLVVQAGLYHGHEMLCKMVSSSE
VNVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKGSLHWPGSTPRNKTRWCNQ
LKTGECCLPMWSSFPDEKGELLNPTGTVRTNPNTESAAALVIRFPGILLYPVYYPSFEQV
RRWWFAPLSLASLVCFLGQWKKVSHLHSLKEILERRSHTELYEHEKDLVWKMRHQVRDQY
PGALAKLLVVTKWNKHEDVAQMIHLLQSWPELPVLNALELLDFNFPDRYVGSFTVNSLKK
LTDAELFQYLLQLVQVLKYESYLDCKLTTFLLDRALSNRKIGHFLFWHLRSEMHVPSVAL
RFGLILEAYCRGSTHHMKSLMRQSEALNKMKALNGIVKLSALKNPKPQTKEFMHTCLRQE
TYLEALSNLQSPLNPSVILAKVSVELCTFMDSKMKPLWIVFNNEEIGGTSNVGIIFKNGD
DLRQDMLTLQMIQLMDILWKKEGLDLRMTPYGCLSTGDKTGLIEVVMDSDTIANIQLNKS
NMAATAAFNKDALLNWLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIR
ENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFREYCER
AYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEARKHFQLKFNEA
LRESWKTKVNWLAHNVSKDNRQ
>A0A8C6PPZ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius furzeri|TrEMBL
MPPGKYGMQEEWEKEGDQNILMDFLLPTGIFLKFPVPRNDTIKNIKKMVWRNAKTEALYC
GLGDPEGYVFTCINDTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNSHISSL
IGKGLHEFEAQKNHEVDEFRSKMRTFCEEKALERHNLPWQQWMEYSFPCDLEPCCSPPVH
GGTKSKHTKNFMLQQDPLDIPVALMKSALKKRATVFRSVRQEPEDYTLQVSGRWEFIYGN
HPLRQFKVSRITSLNLANHMSCLIITLCISVLPSLPHHHHHLQLVVQAGLFHGSELLCKV
VTSSEVTVCSEPLWDQKLDFDINVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKRADCP
IAWVNTMVFDYKDQLKTGEFILSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPN
IRPHPLYYPPLDKMIVMERNGDAVFRMRLKEIMDNKNSTEFFEDEKELLWKLRTEVRDCY
PESLSKLLLITKWSKREDVVQMVSLLRNWPDLPAIQALELLDYSFPDPAVRSFTIRCLRK
LSDNELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVSL
RFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDIVKSGCQKMTVEDLKLCIRQESYME
ALSNLMSPLNPSIILVDADKCRFMDSKMKPLWMMYKNPSEHADMVGIIFKNGDDLRQDML
TLQMIHLMEDLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKHSDTIANIQRNNSNSAATAA
FNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFH
IDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFREYCEWAYKILCKNGT
LFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVN
WMMHSLAKDNRP
>A0A2K5K6D7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Colobus angolensis palliatus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDGPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
TEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKCKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVHSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A668UHP6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRSKMFRISEERMQQIQMMTFSEWVQACYSPQLEPA
AVTAITAGVNDAPVDLKVIIHFDQSQDSASLKVSLSCTPNELMEQALRKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKETPHLTLVHTSAVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRRAPTVSWLVIVKFNPSCITQVQVRAGLFHGTELLCKPAVSNE
SSGRSEHTWKDNTLEFEISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNPHINKYQTIRKA
GKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATAL
HIHFPEYSSHPIVFPPFDKILEKAAEMVSADCVSIGRGVKKFYMELKEIMERDPVSQLCE
NEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDF
NYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQRNRRRRG
NIHMPAVSVQFALILEAYCRSNIPHIEVLKKQVEALSKLKSVNELIKLGTIKNTRSKTKE
AMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDINVEKCRYMDSKMKPLWIVYNNKL
LSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRTGLIEVV
SSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFTLSCAGYCVATYV
LGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTG
NTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTD
EEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A553NHG1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Danionella translucida|TrEMBL
MYIGGAYQSWAASGPVKPRARFRALTGRLYPNSGFTSLQLSGEKKVGLKIQIMPPRPSSG
ELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHHLLQEETSY
IFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEF
DLVKDPEVQDFRRNILNVCKDSVELRDSSGSHSRALYVYPPNVESSPELPKHIYGKLDKG
QIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLKMCVQEYQG
KYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMDNFTMPSYA
RRISTATPYMNGEASSKPLWTISSSLRIRVLCATYVNVNIRDIDKIYVRTGIYHGGEQLC
DNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVN
LFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYFTSPLKFPD
MATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTDADIDQLRQLSNRDPLSEITEQEK
DFLWRHRHYCANLPEILPKILLAVKWNSRDDVAQMYCLLKDWPAIKPEQAMELLDCNYPD
PMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFF
WHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQ
KVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDI
MSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLI
EVVRSSHTIMQIQCKGGLKGALQFNSTTLHQWLKDKNKGEMYDMAIDLFTRSCAGYCVAT
FILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGG
TQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLA
LDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A668TN33|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDSEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>M3Y4E1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mustela putorius furo|TrEMBL
MPPGVDCPMEFWAKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGKHEYLYGSYPLCQFQYICSCLHSGQTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCLR
QETYLEALSHLQSPLDPSTLLADVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A3P9BH40|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Maylandia zebra|TrEMBL
MAPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLTTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYSKLDKGQIIVVIWVIVSPTNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMD
FFTMPSYARRISTATPYMNGETATKNLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLTYDMYIPEVPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHY
SSPVKFPDMSTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDGDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHDCINMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMVREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A3P9DR10|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Maylandia zebra|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVMRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRSKMFRISEERMQQIQMMAFSEWVQACYSPQLEPA
AVTAITAGVNDAPVDLKVIIHFDQSQDSASLKVSLSCTPNELMEQALKKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKEAPHLTLVHTSTVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRSLHLWPLAGWLVIVKFNPSCRTQVQVRAGLFHGTELLCKPAV
SNESSGRSEHTWKDNTVEFEISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNPHINKYQTI
RKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENA
TALHIHFPEYSSHPIVFPPFDKILEKAAEMVSADCVSIGRGVKKFYMELKEIMERDPVSQ
LCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALEL
LDFNYPDQYVREYAVRCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQRNRQ
IGHFLFWHLRSEIHMPAVSVQFALLLEAYCRSNIPHIEVLKKQVEALSKLKSVNELIKLG
TIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDINVEKCRYMDSKM
KPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAHLDLRIVPYGCLA
TGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFTL
SCAGYCVATYVLGIGDRHSDNIMVRSNGQLFHIDFGHILGNFKSKFGIKRERVPFILTHD
FIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A3S2MN36|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias javanicus|TrEMBL
MHPGIYGMLEEWEDGEKEINMDFLLPTGIFLKFPVSRNDTIKHIKEMVWRNARSEALFSG
LGDPDGYVFTCINQTAEREELEEEFRRIRDVKPFMCVLRLVAREGNRQEKLTNTQISLLI
GKGLHDFETQKNHEVNEFRTKMRAFCEEKALERQNLPWQRWLEYSFPCDLEPCRTPSGFG
SVKIKSSKIFINVKFEASDESFMLQQDCHDLPVALMKSALKKKATVFRSLRQEPEDYILQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPQLTMVHHSTVSRFQEEQSRMCNQMFKTRSL
SRPPPLPLKRQNTSSLWSINELFYIQLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTS
LDVTVCSEPMWDQKLEFDINVSDLPRMSRLCFALYAVIEKTKKPKSTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSMWPSVPDDKSDLLNPMGTVEKNPNVESAAGLLIRFPNIRP
HPLYYPSLEKLIDFEKNGDVVCTPKDEHLKLKEIMDNKHYTEFFEDEKDLLWKLRTEIRE
HYPESLSKLLLVTKWNKREDVVQMVSLLKKWPDLPAIHALELLDYSFPDPAVRSFTVRCL
RKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASV
SLRFGLILEAYCRGNIHHIKILNKQNEALAKMRALSDFVKSGSQKMTAEDLKLCIRQETY
LEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNPSSPGDMVGVIFKNGDDLR
QDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSA
ATAAFNKDALLNWLKSKNPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYK
ILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDNRP
>A0A3P8RAK3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astatotilapia calliptera|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKSIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRAFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKTKNIKKIFINVKFEASDESFMLQQDPHDLPLVLMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTVTKCQEEQGRMCNQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPCVPDEKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKYFKLKEFMDNKNYTEFFEDEKELLWKLRTEVRDHYPESLSKLLLITKWNK
REDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLRKLSDDELLHYLIQLVQ
VLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASVGLRFGLILEAYCRGNIH
HIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESYLEALSDLLSPLNPSIIL
SEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWK
KEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGN
FKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLF
AMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEALRESWKTKVNWMMHSL
AKDNRP
>A0A6P7JHA6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Parambassis ranga|TrEMBL
MDRQQIQVSDEEPEVLREECRRRRRKKAITSSSSISMDQITVEFVLPTAARGGSSPDSLL
LEVAGNWTVEQVKAQVWLKAVTLNFCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRQQPTDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDSKLYSMDPWVTRKPLPEHLLAKVSNGHILVVIHIGTASQTIKVSID
DTPTQVLAGFFTKMANKRVLLGIPDNMCEADFVLRVCGREEYLYGERPLQNFNWIRQCLK
NGEEIHLVLETPSDPDLELVQKEDWAQVDDCTGVAGTHEQLTIDGKDHERVFTISMWDCN
RKFRVKVLGIDIPTLPKVPEFIVFIEASIFHGQQRLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKQPQTPNSKGAPYLDNTSGTGSLDGKTKMRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAISILLDKYCYPVVLP
KSRDVGRDSGAGGDEAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHD
CMRDPRAYPKLLGSVKWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVR
SMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSMHYQQRYAVLLEAYLRGCGENMLQDFRKQVEMTEALQKVTREIKAMSADKYDVTA
QVVFQLRQKLETVQSSGLPESFRVPYDPGLRAGALMIEQCKVMASKKKPLWLQFKRADPT
TLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKK
SSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRGE
DEAQHHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A850XR35|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aegithalos caudatus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCASSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSVEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRYEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEVNIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIPSD
TQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVISQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K7RBK3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nesospiza acunhae|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAIDTSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVTEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A4W3H3Y9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPGMQYHQDLWSEDENPDVEVEFLLPTGIYLNFYVPRSSTISYIKKLLWQQAQQQPLFH
TLNEPDAYVFTCINHTAEREELEDERRRLCDVRPFLPVLKLVAREGDRAEKLINSQISLL
IGKGLHEFDCMQDYEVAEFRLKMRQFCEDKESERLRMSWQDWMEYSFPRELEPIQESSQF
TVYSVNCLCSVPRPNLNLYLLNQESFSFQISPQSHPGTLMQMAVKKKATVFRHKTVEHTE
DYTLQVNGTEEYIYGNYPLGQFKHIWNCMYSSSTPHLTMVHSSTINSLKGEQSNSIAQVP
KSRTYSKPPPLPIKKVIIARSSFHRCFPFSPPQLVVQAGLFHGSEMLCKTVSSHEVSVCS
EPAWDQALEFDIHFSDLPRMTRLCFALYGVIDKAKKARSTKKKSKKADCPIAWVNTMVFD
YKDQLKTGDVWLHMWPSIPDEKGELLNPMGTVQGNPNTDSAAALYVRFRNMGSYPIYYPS
FDKVCTELIPRGLLCLDGVRFGWWKEPSRGEGLKEIMERKSCTEFFEDEKDLVWKLRWES
RDHYSDALAKLLSITKWNKHEDVAQMIYLLQSWPELPALHALELLDYSYPERYVRSFAIN
CLKNLSEEELFQYLLQLVQVLKYEPYLDSELTKFLLNRALANKKIGHFLFWHLRSEMHVP
AVSLRFGLILEAYCRGNNYHMKSLMKQCESLKKMKALNDFVKSSSQKTTKPKTKEALHLF
MRQEAYMEALSNLHSSLNPSSLLTDLWVDKCKFMDSKMKPLWIVYKNEKYDGDPMGVMFK
NGDDLRQDMLTIQMIQLMDVLWKRQGLDYRMIPYACLSTGDKTGLIEVVSRSETIANIQL
NKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRENGQLFHIDFGHFLGNFKSKFGINRERVPFILTHDFVHVIQQGKTSNSEKFERFRKY
CEHAYMILRKHCPLFINLFALMRAAGLPELSSSKDIQYLKDSLALGKTEEEALKHFKMKF
DEALRESWKTKVNWMAHNVAKDNRS
>A0A3B4DGT6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pygocentrus nattereri|TrEMBL
MVWLWCALYHASRHDGSVGCVVRSRAGWRRPGNCGFLVAYWNLHSDGCSPREHHPTDQTG
EIDSHIFECVNQAAVHEELEDESRRLCDVRPFLPVLKLITRNCGRAERLLDSKIGVLIGK
GLHELDALQDQEVKDFRIKMQRISEEKMQRVQTMSWGEWLHSCFPPQIEAGPFEDDRNEG
DIKITMHYNQSQDTASLKVSLSCTVAELMEQALRKWLTTHSSEENKGYLGDYVLRISGKL
DFLFGEHTLIHYKYIRSCLLAQEIPHFTMVHCSDVMAMFEHEISTIGAVLTRKSSNPPLP
LPPKRRGLSQMHTCVWEVHSLFKIILVKGIKVNADETAKVQVRAGLFHGTELLCKPAVSN
ESSGRSEYVWNRTLEFEISICDLPRMARLCFAIYAVMDKVKKQKSTKNAQMNKYQTIRKA
GKVHYPIAWVNTMVFDYRGQLKTGDIILHTWSSFPDELEEMLNPIGTIQTNPYTENATAL
HIRFPEYSTHPVIFPPFDKILEKAAEIAGASDSMSMGRGGKKFHIELKEIMERDPLSQLC
ENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPRLHPRDALELLD
FNYPDQYVREYAVSCLQDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLERAQTNRKIG
HFLFWHLRSEIHMPAVSVQFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKLGTI
KAKNKTKEAQLKEAMMKCLRQTGFIETLSDLHSPLNPQVLLGGVNVEKCRYMDSKMKPLW
IVYHNKLLVGDTLGIIFKNGDDLRQDMLTLQILKLMDILWKEANLDLRVVPYGCLATGDR
TGLIEVVSSADTIANIQKNSSNMAAAAAFNKDALLNWLKDKNPGDALEKAIEEFTLSCAG
YCVATYVLGIGDRHSDNIMVCSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHV
IQQGKTGNTEKFGRTLLHWVRQMKRL
>A0A7L4L114|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callaeas wilsoni|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPVTLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAALEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
SSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C5SYL2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Laticauda laticaudata|TrEMBL
MELETSDQAVVMRDDNKRRRRRRMKPYCTANTLSSTELISIEFVFPTTSIVLDVPTNCTV
EQMKAQVWMWAVEGHQTSDLFRKITPDQFLLLYQKKGQWYEIYDKHQIIQTLDCILYWKV
LQKKVGKIHVVEKPNPSDEVQDFQNQLNYLIGYDVTDVSNVHDDELEFARRRLVTPRTIE
VSCRDPKLYSMSPWTTSKPLPEYLLSRIANSNIFINIHRGTTSQKIKVAVDDTPDIILQS
FFTKMAKKKSLMNIPEDYSEQDFVLRVSGRDEYIVGETPIKNFHWIRQCLKKGDEIHLVL
DEPPDSNQDEVQKEEWPLVDDCTGVSGYHEQLTIHGKDHERVFTISLWDCNRKFRVKIIG
IDIPILPRNTDLTVFVEANIQHGQQLLSQRRTTAKPFTEEVLWNVWLEFDIKIKDLPKGA
LLTLQIYCGKTPLPSAKGNLHPQDSPSTDPKYKTQLLYYVNLLVIDHRSLLRTGDYVLHM
WKIPGKGEEQGSINADKLTSATNPDKENSMAVSIVLDKYCHPITLPKHKIASDPLEGRAR
VEMPNQLRKQLEEIIATDLLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQKLV
AETYQLLAKREAWDQSALDVGLPIQLLDCNFSDETVRTMAVQKLEGLEDDDVLHYLLQLV
QAVKFEPYHDSALARFLLKRSLKNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGC
GKAMLKDFLRQVQVTELLHKVTREIKAVSAEKYDVTPQVIAQLKQKLERLQDNKFPECFR
VPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTSLSSETIGIIFKHGDDLRQDMLI
LQILRIMASIWEEESLDLCLLPYGCISTGNKIGMIEIVKDANTIAKIQQSTVGNTGAFKD
ETLNQWLKDKCVIEEKVRVPITAIAIISV
>A0A1U7TPX5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carlito syrichta|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A1S3MDI9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo salar|TrEMBL
MPPGEYGMLGEWKKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRPFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPMILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTIVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKQNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKV
VTSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKTKKPRSTKKKNKKADCP
LAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFPN
IRPHPLYYPHFDKLRDLEKNGGKVIATKVEHMKLKEIVDNKNYTEFFEDEKELLWKLRGV
VRERYPESLSKLLLITKWNKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTI
SCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLKSEMHV
SSVSLRFGLILEAYCRGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKL
CIKQEAYMEALSYLLSPLNPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIF
KNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQ
RNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDN
IMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRE
CCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVK
FNEALRESWKTKVNWMMHSLAKDSRL
>A0A7K9GEE6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Loxia leucoptera|TrEMBL
MELGDHDQPVVMRDENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQRQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRMKIIGIDIPVLPRNTDLTVFVEANIQHGQQILSQRRTSSKPFTEEVLWNMWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A4W4EWV8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MPPAMTDLLDLWVEPGLDGDDQVTVDFLLPTGVYIKMDVPRQSSLQCIKQMLWKQAQGYP
LFTLLGEMDSHIFECVNQAAVHEELEDESRRLCDVRPFLPVLRLIARNCGRAERLLDSKI
GVLIGKGLHELDALQDQEVKDFRSKMQRISEENMQCVHMMSWGEWLQSCFSPQIEAGPVN
GYCDGSEGEVKIIMHYSESQVQTDVHVNFYQSCTVAELMEQALRKWLTTHGSEEDEGCLG
DYVLRVSAKLEFLFGDHPLHHYRYIRSCLLAQEVPHLTLVHCSVVKAMFEREICTIGGVL
AWKASNLPLPLPPKKRGLTVSVHTCVWEVHSQFKITLVKGIKVNAEETVQVRAGLFHGTE
LLGKVAVSSESSGRSEHVWNKALEFDLSICDIPRMSRLCFAIYAVMDKVKKQKSTKSVQM
NKHQTIRKSGKLLYPIAWVNTMVFDYRGQMKTGDITLHTWSSFPDELEEMLNPIGTIQTN
PYRENATALHIRFPEYSPQPVVFPPFDKILEKAAEIAGASDTLSMGRGGKKFYVELKEIM
ERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLS
PRDALELLDFNYPDQYVREYAVNCLQDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLR
RAQANRKIGHFLFWHLRSEMHMPAVCVQFALILEAYCRCSVPHIEVLKKQVEALSKLKAV
NELIKLGTIKTKKMKEAQLKDAMMKCLRQTGFIETLSDLHSPLDPQVLLAGVNVERCRYM
DSKMKPLWIVYNNKLLVGDTMGIIFKNGDDLRQDMLTLQILRLMDILWKEANLDLRIVPY
GCLATGDRTGLIEVVSYSETIANIQKNSSNMAAAAAFNKDALLNWLKDKNPGDALEKAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFI
LTHDFIHVIQQGKTGNTEKFGSFRQNCEDAYLILRKNGNLFITLFALMLTAGLPELTSVK
DIQYLKDSLALGKTDEDALKQFRQKFDEALRESWTTKVNWMAHNDWRVGELS
>A0A1L8GB27|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus laevis|TrEMBL
MPPITDHTDIWTADTPLPPDICVDILLPTGIYVQMEVPRNASISHIKQLLWKHAQSYPLF
HLLLEIDTYMFQCVNQTAVHEELEDETRLLCDVRPFLPVLKLVSRSCNPAEKLDSKIGVL
IGKGLQEFDALKDNEVIEFRSKMRSISEGKIQSLLGLTWIEWLKCTFPPELEPSVQDNIQ
GKLYGGNIVVAIHFENCQDVFSFQVSPNMAPVKINELAIRKRLTIHGRETEGVDPEDYVL
QVSGRMEYVFGDHPLIQFQYIRNCVMNKTLPHLTLVECCNIKKLFDQEMSEIEHAVRRKS
SLHPALPMPLPPKKRGASVKTLNMRDIVWNIVQPYKIILSRGSRLNTEDNVLVRAGLFHG
TELLCKPTVSLEKQGKNDHVWNEILEFEINVCDLPRMARLCFAIYAVLDKPRNKNKTKPS
NPKYQTIKKSGKMNFPVAWVNTMVFDYKGQLRSGDNVLHCWSSFPDELEEMLNPMGTVRT
NPYTENATTIHIKFHDYSKEPISYPPFDKILEKAAEIARNSDSLSTTGRGGKKFNIELKE
IMERDPLCQLCENEKDLIWTLRYDCRENFPGSLPKLLLSVKWNKLEDVAQLQALLQIWSK
LPPRDALELLDFNYPDQYVREYAVNCLKHMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LQRALDNRRIGQFLFWHLRSEVHIPAVSVQFGLLLEAYCRGSVAHMKVLSRQVEALNKLR
TLNGLIKLNAVKLSKVKNKDTMHTCLRENAYKEALAHIQSPLNPSITLSELVVEKCKYMD
SKMKPLWIVYNNRGFGSDSLGIIFKNGDDLRQDMLALQLLRLMDMLWKEAGLDLRIVPYG
CLATGDRCGFIEVVSAADTIADIQLDSSNLAAAAAFNKDALLNWIKECNSGDDLERAIEE
FTLSCAGYCVATYVLGIGDRHNDNIMVRKTGQLFHIDFGHILGNFKSKFKIKRERGPFIL
TYDFIHVIQQGKPGNTEKFGRFRQCCEEAYLILRRNGNLIITLFALMLTAGLPELSSVKD
IQYVKDCLALGKTEEDALKQFRQKFDEALKESWTTKVNWMAHTMRKDYKA
>A0A3P9DRK9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Maylandia zebra|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVMRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRSKMFRISEERMQQIQMMAFSEWVQACYSPQLEPA
AVTAITAGVNDAPVDLKVIIHFDQSQDSASLKVSLSCTPNELMEQALKKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKEAPHLTLVHTSTVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRRPPTQVQTCVWDVPKPFRIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSNESSGRSEHTWKDNTVEFEISVCDLPRMTRLCFAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHPIVFPPFDKILEKAAEMVSADCVSIGRGVKKFYMEL
KEIMERDPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVRCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTH
FLLERAQRNRQIGHFLFWHLRSEIHMPAVSVQFALLLEAYCRSNIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAHL
DLRIVPYGCLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSNGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A6J2S854|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cottoperca gobio|TrEMBL
MDGRQIQVSDEEPKVVQEEPRRRRRKKAISSSSYSCMDQIAVEFVLPTAVRGGHGPDSLQ
LEVAGNWTVEQVKAQVWLKAVTLNLSPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKEVGRIQLVPRPQPSDESLQYQRYLNYLIAYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDAKLYSMDPWVTRKMLPERLLSKVSNGHFLVVIHISTASQTIKVSLA
DTPAQVLLSFFAKTANKRVLLGLPESWSEADFVLRVCGREEYLYGEKPLQDFNWVRHCLK
NGEEVHLVLETPPDTDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RRFRVKVLGIDIPSLPKIPELIVFIEASIFHGQQLLAQERTSSKSFSEEVLWNCWLEFNI
KIRDLPKGARLNLQVVCGKQPLTPNSRGASAYQDAAAGSHDGKTKSRLLYYVNLLLVDHR
SLLRQGEFILHMWKMPEKSEESSSSSINADKLTSATNPDKASAMAVAILLDKYCYPVVLP
KSRDVSRVAGAGGEEAEGERGQREMPNHLKKQFAAIVDTDPLHPLSPEDKELLWHFRHEC
LRDPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRS
MAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALKSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGEEMLQDFRKQVEMTEALQKVTREMKAMYADKYDITAQ
VVFQLRQKLETLQSTGSPQSFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTT
LSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIV
KDATTIANIQQSVVGSTGAFKDEILHQWLRDKCVSEDKFQQAVEKFLLSCGGYCVATYVL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKS
SPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPHLTSKEDIEYIREALTVGRSED
EAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKHST
>A0A6P8SDP9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MPPRPSSGELWGIHLMPPRIQVECLLPNGMMVCLECLREATLVTIKHELFKEARKYPLHH
LLQDESSYIFVSVTQEAELEEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDMVKDPEVQEFRRNVLNVCKEAVDLRDANGPQSRALYVYPPNVESSPELPKH
IYAKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPVD
NFTMPSYSRRISTATPYMNGEASVKPLWTINSSLRIKILCATYVNVNIRDIDKIYVRTGI
CHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGMEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMMVIEEHANWTISRELGFNYSHAGLSNRTARDCELRESDKEQLRAVCTRDPL
SEITEQEKDFLWSNRHYCLYTPEILPKLLLAVKWNSRDEVAQMYCLLKDWPPIKPEQAME
LLDCNYPDPMVRAFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFSSPLNPAHQLGTLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRCFLKKKIR
MLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGIKGALQFNSHTLHQWLKDKNKGEMYDA
AIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERV
PFVLTQDFLIVISKGTQECTKTRDFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPE
LQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A6P8NWM4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCIPNGMIVTLECLREATLLGIKHNLFKEARKYPLFH
LLQDESSYIFVGVTQEAEREEFYDETRRLCDLRLFQPILKVIEPVGNREEKILNREIGFA
IGMPICEFEMVKDPEVQEFRRNILSVCKEALDLREASGPHSQALYVYPPNVESTPELPKH
IYNKLDKGLIIVTIWVIVFPNNDKQKYTLKIPHDCLPEQVIADAIRKKTRSMHLSPEQLK
LCVQEYQGKYILKVCGCDEYLLEKYPFSQYKYIRNCITIGRLPHLMLMSKESLYGQLPAN
IFIMPSYARRSVTSCYMNGDVPTKSLWSINSLLRIRILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYLTDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINLFDYKDTLVAGKMALNLWPVPHGLEDLLNPIGVGGSNPNKETPCLELEFSWYT
HAVKFPDTPQIEEHANWSMSRELGLNYCLVGLSNRLARDSSLIENEMEQLRNICNRDPLS
EITEQEKDFLWRHRHYCINIPETLPKLLLSVKWNSRDEVTQMYCLLREWPLIKPELSLEL
LDCNFPDPMVREFALKCLVKGLTDDKLSQYLIQLVQVLKYEQYLDNILARFLIKKALTNQ
RIGHFFFWHLKSEMHSKTVSQRFGLMLEAFCRGCGMYLKHLNRQVEAMEKLINLTDILKQ
EKKDETQKMQMKFLMEQMRRPAYMEALQGFICPLNPVHQLGNLRLEECRIMSSAKRPLWL
NWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIRIMENMWQNQGLDLRMLPYGCLSI
GDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWLKDKNKGTMQPLISSLGPVLD
TVLPLSSWASEIGTIATSW
>A0A8J6KI92|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eleutherodactylus coqui|TrEMBL
MELENYEQPVVLRDENKRRRRKMRPHSAATSSMFSMEAIPVEFILPTSHKNSKVQDTILL
EIAGNCTVEQMKAQVWMSAIEKSHNSDFYHRLAPDQFLLQYQKKGQWYEIYDKHQVIQTL
DCIVYWKVLQKTVGKIYIIQKEKPSEETLEYQKQLNYLIGYDVTDVSNVHDDELEFTRRR
LVTPRMIELVKRDARLYSMDPWVTSKPLPEYLCKKISTNNIFIIIHKGMTSHTIRVSIDD
TPDVILQSFFTKMAKKKSLLDISEEHSELDFVLRVCGRDEYLIGNAPIKDFHYIRQCIKN
GDEIHFVLDVPPDPSEDKVQKEEWPLVDDCTGVTGFHEQLTIDGKDHEKIFTISLWDCNR
KFRVKVIGIDIPSLPRNTELIVFVEANILHGQQVLSQRRTSCKPFTEEVLWNTWLEFDIK
IKDIPKGALLNLQIFCCKAQTATGKSNIQSSDSTSSDSKFKNQLLYYVNLLLIDHRSLLR
QGEFVLHMWRIPGKGEDQGSINADKLTSATNPDKDRSMAIAISLDKYCHPVALPKHKSVS
DPELDRARSEMPNQLRKQLEEIISTDPLHPLTPEDKELLWHFRFEVMKNPDAYPKLLSSV
KWGQQEMVAKTYQLLNKREAWDDCSLDVGLTIQLLDCNFSDENVRAMAVQKLESLQDDDV
LHYLLQLVQAVKFEPYHDSALSRFLLRRALRSKRIGHFLFWFLRSEIAQSMHYQQRFAVI
LEAYLRGCGTSILNDFMKQVQVTEVLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQG
SYLPESFRVPYDPGLRAGALVVEKCKVMASKKKPLWLEFKCADTTALSNETIGIIFKHGD
DLRQDMLILQILRIMESIWEGESLDLCLLPYGCISTGNKIGMIEIVKDATTIAQIQQSTV
GNTGAFKDEVLSQWLKEKCPLEDKLNAAVERFVYSCAGYCVATFVLGIGDRHNDNIMVTE
TGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLHVMGTSGKKTSEYFLKFQDVCVKA
YLALRHHTNLMIILFSMMLMTGMPQLTSKEDIEYIRESLTVGKNEDNAKKHFLDQIEVCR
DKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A2J8TAD9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pongo abelii|TrEMBL
MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGEAPIKNFQWVRHCLKNG
EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A1S3T220|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo salar|TrEMBL
MPPAMTNLMDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQQVQLMTWSEWLQACFSPQLEPGGG
ATPVTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISA
IGAVVNRKSSIPPLPLPPKRRGPSQVNTCVWEVSTHFKIVLIKGSKVNAEETAKVQVRAG
LFHGTELLCKPAVSSESSGRSEHVWNSTLEFDITVSDLPRMTRLCFAVYAVMDKVKKQKS
TKNAHINKYQTIRKSGKVHYPVAWVNTMLFDYKGQLKTGDIVLHSWSSFPDELEEMLNPI
GTIQTNPYTENTTALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCLPMGRGGKKFHI
ELKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQ
IWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCAL
TRFLLNRAQCNRNIGHFLFWHLRSEMHMPAVAVQFSLILEAYCRGSIPHIEVLKKQVEAL
SKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSG
INVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEA
NLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNS
GDALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFG
IKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTA
GLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A8C6J910|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Melopsittacus undulatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSSELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYILDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8D0DS01|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salvator merianae|TrEMBL
MELMNTTEQPVVMREDNKRRRRRMKPHCTANSLSSTELITIEFILPTSNMLVDIASNCTV
EQMKAQVWMQAIERNQTSDFYQNFTPDQFVLQYQKKGQWYEIYDKHQIIQTLDCILYWKV
LQKKVGKIHVVQKQKPSEEVQAFQKQLNYLIGYDVTDVSNVHDDELEFARRRLVTPRTIE
VTCRDPRLYSLHPWTTSKPLPEYLLNRITNNNIFINIHRGTTSQKIKVSLDDTPDLILQS
FFTKMARKKSLMNIPEDHSESDFVLRVSGRDEYIVGDTPIKNFHWIRQCLKNWDEIHLVL
DIPPDPNLDEVQKEEWPLVDDCTGVSGYHEQLTIDGKDHEKVFTISLWDCNRKFRVKIIG
IDIPVLPRNTDLTVFVEANIQHGQQLLSQKRTTAKPFTEEVLWNTWLDFDIKIKDLPKGA
LLTLQIYCGKAPASSTKTNLQPYDSPGSDSKSKIQLLYYVNILLIDHRSLLRTGDYVLHM
WKFPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHKIAPDSHGDRVR
AEMPNQLRKQLEEIIATDLLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQETV
AETYQLLAKRDAWDHSALDVGLTMXLLDCNFSDENVRAMAVQKLESLEDDDVLHYLLQLV
QAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGC
GKAMLQDFLKQVEVIELLHKVTMEVKSVSAEKYDVTPQVITQLRQKLERLQDSKLPECFR
VPYDPGLKAGALVIEKCKVMASKKKPLWLEFRCADPTSLSXETIGIIFKHGDDLRQDMLI
LQILRIMETIWEEESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTGAFKD
EILNQWLKEKCVIDEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITESGNLFHID
FGHILGNYKSFLGINKERVPFVLTPDFLFVMGTTGKKTSLRFQNFQVQEYNL
>A0A8C3ITR8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysemys picta bellii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVCPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWVINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMTVIEEHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A2K6MYJ4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinopithecus bieti|TrEMBL
MELENYEQPVVLREDNCRRRRRMKPRSAATSLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVASDFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPQVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFTIKI
KDLPKGALLNLQIYCGKAPAVSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDTCVKAYLAL
RHHTSLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGENIQPNTLG
>W5K1U1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MPPAMTDQLDVWSDPGLDGDDQVAVDFLLPTGVYIQMDVPRESTIQQIKQILWKQAQDYP
LFSLLGAIDDHIFECVNQAAVHEELEDESRRLCDVRPFLPVLKLIARDCGRAERLLESKI
GVLIGKGLHELDALQDQEVKDFRSKMQRNSEEKMQCVQMMSWGEWLQSCFSPQIEPGPID
EIYDARNENDIKITMHYNQSQDTASLRVPLSCTVAELTEQALRKWLTTHGSEEDGGSLAD
YVLRVSSKLEFLFGEHALIHYKYIRMCLLAQEIPHLTLVHCSEVKSMFERELTSIGAMLT
RKTSNPPLPLPPKRRGMSQMHMCVWEINSIFKITLVRGIKVNAEETAKVQVRAGLFHGTE
LLCKPAVSSESSGRSEYIWNTSLEFDISVSDMPRMTRLCFAIYAVMDKGKKQKSTKNTAM
NKYQTIRKAGKVHYPIAWVNTMVFDYRGHLKTGDIILHTWSSFPDELEEMLNPIGTIQTN
PYTENATALQISFPEYSQCPVVFPPFDKILEKAAEIAGASDSMSMGRGGKKFHIELKEIM
ERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLS
PRDALELLDFNYPDQYVREYAVGCLKYMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLE
RAQTNRKIGHFLFWHLRSEMHMPAVTVQFALILEAYCRGCIPHIEVLKKQVEALSKLKAV
NELIKLGTIKSKNKTKDAQLKEAMMKCLRQTGFIETLSDLHSPLNPHILALHFVERCKYM
DSKMKPLWIVYHNKLLVGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPY
GCLATGDRTGLIEVVSSADTIANIQKNSSNMAAAAAFNKDALLNWLKDKNPGDALEKAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFI
LTHDFIHVIQQGKTGNTEKFGSFRQYCEDAYLILRKNGNLFITLFALMLTAGLPELTSVK
DIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAHRS
>V8N614|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ophiophagus hannah|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCLPNGMVVTLECLREATLRGIKQDLFKEARKYPLFH
LLQEESSYIFVGVTQEAEREEFFDESRRLCDLRLFQPILKVVEPVGNREEKILNREIGFA
IGMPICEFELVKEPEVQEFRRNILSVCREAVETRGCSGPQSQALYVYPPNVESSPDLPKH
LYSKLDKGRVIVTIWVIVSPNNDKQKYTLKTPHDALPEQVIAEAIRKKTRSMHLSPEQLR
LCVQEYQGKYLLKVCGCDEYLLEKYPLSQYKSPAPSDNADRSWRGRGKEEEKEEKDKEEE
EEEEKEEEKEEKEEEEEEEEEEEEGKEEKEEEEKEEEEQRRKKRKRNKGGERGRGGRERG
GGRGREGGERGKRGRGGERKRKRKKRRRKRRKRRRKKEEKEEKEEEKEEEEKEEKGEEKE
EEGEEGGGRGGGGRGGRRVHEELHRHWPPAPPHADEQGEPLQPAASQRLRAALVRAPVSH
LLAREWRCAHQVPLVHQQPPAHQDPVRHLRQREHQGHRQDLCPDGNFPRWGTPL
>A0A671T2X4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPAKTDQLDLWAESGLDGDVQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSCGEWLRSCYSTQLGTGSLE
NLIDKHEGDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDYVLRVSGRFEFLF
EDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLARKTSNPPLPLPPK
KRPPTVSTLSVFPALQLIKGIQVRAGLFHGTELLCKTAVSSESSSRSEHVWNKTLEFDIA
VCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIPWVNTMVFDYRGQLKTGDIILH
CWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVFPAFDKFLSSVEHKEC
VLKNVENQTVLKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHED
MAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVICLRDMSDDELLQYLLQLVQVLR
YEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIE
VLKKQVEALNKLKAVSELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLQSPLNPN
ILLAGVHVERCKYMDSKMKPLWIVYNNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDL
LWKEANLDLRDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHI
LGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFI
TLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMA
HIVAHPS
>A0A8C0HLS1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Buteo japonicus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPAKNIFVNVRFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGQTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAL
HPVYYPSFEQVGDVDAFFGRLRHSLMISLLQTWPELPVLNALELLDFSFPDRYVGSFAIN
SLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVP
AVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMC
MKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFK
NGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQL
NKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGY
CEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKVREAEPR
>A0A3L7HMD8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cricetulus griseus|TrEMBL
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFILPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDHFLLLYQKKGQWYEIYDRYQVVQTLD
CLRYWKMMHKSPGQIHVVQRHAPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKITNNCILIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMNIPESQSERDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
DEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPTLSSKASAEMPGSESKGKAQLLYYVNLLLIDHRFLLRHGDY
VLHMWQISGKVEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGMAMLQDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSSLP
KSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFQCADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETECLDLCLLPYGCISTGDKIGMIQIVKDATTIAQIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQRNPVLKEKKD
VCVRAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQ
IE
>A0A2K5PV11|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cebus imitator|TrEMBL
MEPAPDLSTSQVPPQKGSCGEACPLMLLWHRAQYEPLFHMLNGPEAYVFTCINQTAEQQE
LEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHEFDSLCDPEVNDFRT
KMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGPGTLRLPNRALLVNVKFEGSEE
SFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYTLQVNGRHEYLYGSYPLCQFQY
ICSCLHSGLTPHLTMVHFSSILAMRDEQSNPAPQVQKPRAKPPPIPAKKPSSVSLWSLDQ
PFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDISI
SDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLHM
WPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAPYPVYYPPLEKILELGRHSECI
RVTEEEQLQLREILERRGCGELYEHEKDLLWKLRHEVQEHFPEALARLLLVTKWNKHEDV
AQMLYLLCSWPELPVLGALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKY
ESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKV
LMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLL
AEVCVEQCTFMDSKMKPLWIMYSNEEAGSSGSVGIIFKNGDDLRQDMLTLQMIQLMDVLW
KQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKS
KNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKT
KFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALM
RAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKD
NRQ
>A0A672U5X4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVHDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMINSIGSVA
SLKFLITLLQVHVRAGLFHGTELLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARL
CFAVYAVMDKMKTKKSTKHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPM
GTVQTNPYTENATALHIRFQEYAKQPINYPPFDKVSCLGISEQQCGKKFYVVLKEIMERD
PLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPRE
ALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERAL
ANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSL
IKLNAMKQSKAKGKDAMQTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKP
LWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATG
DHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSC
AGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFI
HVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7L0F603|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Corythaixoides concolor|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GALHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPLKMA
PKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKTLNDIVKMSSQKATKPQTKEVMHV
CMKQETYLEALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C7H5V4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRVKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQLSKS
RSLSKPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVV
TSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIHFPNI
RPHPLYYPHFDKVHLILHTHLQYVHSTPSLLTLYCAAQHMKLKEIVDNKNYTEFFEDEKE
LLWKLRGVVRERYPESLSKLLLITKWNKHEDVAQMVTFLQKWPDLPALHALELLDYSFPD
PMVRSFTIRCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFW
HLRSEMHVSSVSLRFGLILEAYCRGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQ
QMTDDMKLCIKQEAYKDALSYLLSPLNPSIKLSEICADRCKFMDSKMKPLWLMYKNKWVQ
GDAVGIIFKNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKN
SDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLG
IGDRHNDNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNS
EKFERFRECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEE
ALKNFKVKFNEALRESWKTKVNWMMHSLAKDSRL
>A0A7K4LRW3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crypturellus undulatus|TrEMBL
MPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWQHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRIKMRQFCEERAAKRQQLSWAAWMEYNFPLQLEPLAKGFGT
GPLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIANPPKLT
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSIAS
HPVYYPSFEQLLELGRNGEQPRTALEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
VRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDGELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVEQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALAKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K4V819|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Emberiza fucata|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTQAPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQSSGMQMFFHSIHMWSSSRLLLPSLLILTWNLGRMIEIVKDATTIAKIQQST
VGNTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMIT
ETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVK
AYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVC
RDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C7MGZ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
CFPLSGFIYRHLDFPLNASSEPLYGALSDADAYVFTCINSTAEREELEDETRRLCDVRLF
MSVLRLVAREGDRVEKLTNTQISLLIGKGLHEFDSQKNHEVNEFRVKMRSFCEEKAQDRQ
RLPWYQWMEYSFSCDLEPCVSLNYQINIFSSDVEILIESFMLQQEPQDLPVILMRSALKK
KATVFRSVRQEKPEDYTLQVNGRWEFIYGKYPLCQFKVSKHNNTTHVLFLSYYQQNTSSL
WSIEEPFHIHLLQGYRVNADEGMKVGVAGLFHGSELLCKVVTSGEVNVCSEPLWDQKLVF
DISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPLAWVNTMVFDYKDQLKTGEF
LLSTWPSVPGDLLNPMGTVEKNPNVDSAAGLLIHFPNIRPHPLYYPHFDKVHLILHTHLQ
YVHSTPSLLTLYCAAQHMKLKEIVDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKLLL
ITKWNKHEDVAQMVTFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQY
LLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAY
CRGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYKDALSYL
LSPLNPSIKLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIFKNGDDLRQDMLTLQ
MIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNK
DALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDF
GHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGT
LFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVN
WMMHSLAKDSRL
>A0A7K9QNX4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Irena cyanogastra|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEDKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGT
GFLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLHQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAAEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C0FZF2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
VYAVLLALQESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYTLQVNGKCEYLY
GNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMAAKPPPLPKKKH
VSSANRSSPCGFMVFPYFSFPQLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFD
INICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVSEATAFFALQDCPIAWVNVMLFD
YKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVASHPVYYPS
FEQHITYTWAVRGQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIIT
KWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDQYVGSFAINSLKKLTDHELFQYLL
QLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCR
GSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHVCMKQETYLEALSHLQS
PLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMI
QLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDA
LLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGH
FLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLF
LHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWL
AHNVSKDNRQ
>A0A3P9KTS6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MPPRPSSGELWGMHLMPPSIVVDCLLPNGMILSLECLREATLVTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILSREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDNNGPHSRALYVYPPNVESSTDLPRH
IYNKLDKGQIIVVIWVIISPSNDKQKYTLKISHDCVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPSD
NFTMPSYARRISTATSYMNGETSSKNLWTINGMLKIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLSYDMYILEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEQF
SSPVKFPDMAYVEEHANWNISRELGFNYSHTGLSNRLARDNPLTDNDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHSCINIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWIKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKEDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8C5NGX4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
MVWKNARNEALFNGLGDPEGYVFTCINQTAVREELEEESRRIRDVRPFMCVLRLVAREGD
RVEKLTNTQISLLIGKGLHEFEAQKNHEVNEFRSKMRSFCEEKAQKRQGLPWQQWMEYSF
PCDLEPCSAKSKNKKKIFINVKFENCCLDNEAPQEPQDLPLALMRSALKKKATVFRSLRQ
EPEDYTLQVNGRWEFIFGKHPLCQFKQNTSSLWAINKPFNIHLLQGSRVNADEGMKVSVR
AGLYHGSELLCKVVTSSEVTVCSEPLWDQKLDFDINVADLPRMSRLCFALYAIIEKAKKP
RGTKKKNKKADCPIAWVNTMVFDHKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPN
VDSAAGLLIRFPNILPHPLYYPPLDKPHLKRTTPFFRFVSQKKMYTKLKEIMDNKNHTEF
FEDEKELLWKLRTDIRDCYPESLSKLLLITKWNKREDVVQMVSLLESWPELPAIHALELL
DYSFPDPAIRSFTIRCLRKLRYSFLFFIIISFLNSDDELLQYLIQLVQVLKYESYLDCVL
TTFLLERALANRRIGHFLFWYLRSEIHVASVSLRFGLILEAYCRGNIHHMKVLTKQNQAL
VKMKALNDFVKSGSQKMTVEDLRLCVKQESYMEALSDLLSPLNPSVILAEICADKCRFMD
SKMKPLWLMYRNPWPHADMLGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYG
CLSTGNKMGLIEVVKNSDTIANIQLNSSTSAATAAFNKDALLNWLKSKNPEDKLEQAIEE
FTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFIL
TYDFVHVIQQGKTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKD
IQYLKDSLALGKSEDEALKNFKVKFTEALRESWKTKVNWMMHSLAKDNRP
>A0A8C5ENU4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
LPTYLFINWFISVHQRLSFQLLWKQAQMFPLFPALGEMESHMFECVNQAAVHEELEDETR
RLCDVRPFLPVLKLVTRNCGRAERLLDSKIGVLIGKGLHELDAINDQEVKDFRSKMFRIS
EERMQQVQMMTCTEWLQACFSPQLEPAASAIISDGVSDLYIIVLVMFQDSASLKVSWSCT
SAELMELALRKWLSTHGPEEDACRGQYVLRVSHCLEFLCGDHPLIQYKQVQTCVWDVSSP
FKIVLVKGSKVNAEESAKVQVRAGLFHGTELLCKPSVSSESNFRSDHTWKDSTLEFDISV
CDLPRMTRLCFAIYAVMDKVKKQKSTKNSIKLLDCIRYHYPIAWVNTMVFDYKGQLKTGD
IILHCWSSFPDELEEMLNPIGTIQTNPYTENATALHIHFPEYLSHPIIFPPFDKRLSTCT
AGLMLFGKQVSLVRLSLLFFIHLFLLFAFQILEKAAEIARASDCFHIELKEIMERDPLSQ
LCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQVLLQIWPKLSPRDALEL
LDFNYPDQYVREYAVGCLRDISDEELLQYLLQLVQVLRYEPYYDCALTHFLIERAHGNRV
IGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLG
TIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSIQLSGINVERCRYMDSKM
KPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRVVPYGCLA
TGDRAGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALERAIEEFTL
SCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHD
FIHVIQQGKTGYTEKFCNFRQNCEDAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKSDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C5HCE7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
MDSELMQVSDEEPELLQEDSLTRRRRRRRKKAITSPSCASMDHITVEFILPTNSHGGSGP
DSLQLEVAGNWTVEQVKAQVWLKAVTLNLSFDFYQRLSPDHCILLYQKKGTVCEIYDKHQ
VFQTLDCIRYWRALKKDVGRIQLVPCPQPSDESLQYQRDLNYLIGYDVTDVSNVHDDELE
FTRRKLLTPRRIELLDRDPRLYSMDPWVTCKPLPKHLLSKVNNGHILLVIHMSTASQTIK
VSINDTPSQVLMSFFTKTANKRALLGIPDNISESDFVLRVCGREEYLYGERPLQNFNWIR
QCLKNGEEIHLVLTAPPDPAMDLVQREDWAQVDDCTGVAGTHEQLTIEEKDHERVFTISM
WDCNRKFRVKVLGIDIPALPKVPELIVFIEASIFHGQQLLAQERTTSKSFSEEVLWNCWL
EFNIKIKDLPKGARLNLQVICGKQQQPSNSKGGSFQNNHPASGSQEGKNKSRLLYYVNLL
LVDHRSLLRQGEFILHMWKMPEKSDESSSSINADKLTSATNPDKASSMAVVILLDKYCYP
VVLPKSRESVSAAKEAEGCDRGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHE
CMRDPRAYPKLLSSVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVR
SIAVRKLETLDDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSKHYQQRYAVLLEAYLRGCGGDLLTDFQKQVEMTEALQKVTREMKATSADKYDVTA
QVVFLLRQKLETLQSTGLPQSFRVPYDPGLKAGALLIEQCKVMASKKKPLWLQFRRADPT
SRSKDPIGIIFKDGDDLRQDMLILQILLIMESIWEAESLDLCLLPYGCISTGNKIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILHQWLREKCVREDKFQQAVERFLLSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLFVMGTSGKK
SSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTASWRGVLSVQS
>A0A8D2AVX8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sciurus vulgaris|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVSDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPCARGARG
PSRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQLLEEQPEDYALQVNG
RHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDAQSNPATPVQKPRTKPPP
VPVKKPSSVSLWSLEQPFCLELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVSV
CSEPVWRQRLEFDISICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAWANLML
FDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTESAATLVICLPEVAPHPVYY
PALEKILELGRHGERGRATEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQEHFPEA
LARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTD
DELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFG
LIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTTKPQTKELMHLCMRQETYL
EALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGVGIIFKNGDDLRQ
DMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMAA
TAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQ
LFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGYCERAYTI
LRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRES
WKTKVNWLAHNVSKDNRQ
>A0A4Y6GNH4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMIPTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETKRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNIESTPDLPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYAISQYKYIRSCIMLGRIPNLMLMAKDSLYTQLSTD
NFVMPSYSRRISTATSYMNGEGAAKSLWAINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDVPCAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHVLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSQVKYPEMNAVEDHANWIISRELGFNYNLSGQSNRVARDHALTDSDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPVVRHFAARCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QKIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMWFLVDQMKRPDYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQISKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTVMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8B6HKQ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mytilus galloprovincialis|TrEMBL
LVQALKYENYLNCDLVKFLLRRALQNRNIGHKLFWLLKSDMHEPSVTVQYGLIIEIYLKA
NPSHMSILDRQQIILQKLKSITDIHTKAANLKKKAKEKDDSPLQKVMQQSAYKEAFCQIY
SPITLMYKLDKIVEKSCKVMDSKKKPFWLEWTNDDEKGQNIQLIYKCGDDLRQDMLTLQI
LEVMDTIWQSEGYDLRLNPYGCVATGCEEGMIEVVQKSLTLAGIQKWRKLGLDKRSLYDW
LKHKNPTEHSLQRAVEEFKLSCAGYAVATYILGVGDRHNDNIMMKETGQLFHIDFGHFLG
NKKTKFNINRERVPFILTSHFEYIIKDGEKKPQNFTHFKEICERAYLIIRSRAHLLIQLF
MMMLSSGIPQLNNVSDIDYIKEVLALNSTQEEALEKFRKKFKEAQESSWSTTVNWWFHMR
VH
>A0A8B6HJW2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mytilus galloprovincialis|TrEMBL
SDMHEPSVTVQYGLIIEIYLKANPSHMSILDRQQIILQKLKSITDIHTKAANLKKKAKEK
DDSPLQKVMQQSAYKEAFCQIYSPITLMYKLDKIVEKSCKVMDSKKKPFWLEWTNDDEKG
QNIQLIYKCGDDLRQDMLTLQILEVMDTIWQSEGYDLRLNPYGCVATGCEEGMIEVVQKS
LTLAGIQKWRKLGLDKRSLYDWLKHKNPTEHSLQRAVEEFKLSCAGYAVATYILGVGDRH
NDNIMMKETGQLFHIDFGHFLGNKKTKFNINRERVPFILTSHFEYIIKDGEKKPQNFTHF
KEICERAYLIIRSRAHLLIQLFMMMLSSGIPQLNNVSDIDYIKEVLALNSTQEEALEKFR
KKFKEAQESSWSTTVNWWFHMRVH
>A0A7K7YNQ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Thryothorus ludovicianus|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQA
HSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRSCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRNDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>H2PXN5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pongo abelii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFESSQGECFQLFPIQYDIGRGFVT
>A0A673N017|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQS
GKSHSGKKILVNVKFEGSEETFVLQQDPQDLPMFLKWNALRKKSTVFRSAKREKPEDYTL
QVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRTRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSCLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGMNGEKVVATKEEHLKLREIVDNKNYTEFFEDEKELLWKLREEVRQ
RYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHVRSFTIRCL
RILRNDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSV
SLRFGLILEAYCRGSIFLIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIK
QDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKDKYDHVGIIFKNGDDL
RQDMLTLQMIQLMDVLWKTEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECC
EQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFN
EALRESWKTKVNWMMHSFAKDNR
>A0A662YXJ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acipenser ruthenus|TrEMBL
MVTMDQIVIEFMLPTYNKFNKIQEALMLDVAGNCTVEQVKTQLWMKAVERSACPEFYQKY
TPDQCILLYQKKGHWYEIYDKHQVFQTLDCIRYWKALKKDLGRIQLVPRPQPTEESEQYQ
RYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPRLIELANRDPKLYSMDPWITPKPLPEYI
LNKISNNNILVVIHRGNASQTIKVSIEDKPDQILQNFFTKIAKKKPLLGISEEDSELDFV
LRVCGRDEYIFGDNPVKNFYWVRQCLKNAEEIHLVLESAPDPEQDVVHKEDWSLVDDCTG
VAGSHEQLTIEEKDHEKVFTISLWDCNRKFRVKVLGIDIPMLPRNSELIVFVEASIFHGQ
QLLAQQRTSSKPFTEEVLWNSWLELDIKIKDLPKGARFSLQVYCGKTQTQSTKAGFQESV
NFDPKCKNRLLYYVNLLLIDHRSLLRQGQYVLHMWKMPEKSEDHSSVNADKLTSATNPDK
ETSMAITVMLDKYCYPIALPKGRESVEVDGERSRREMPNHLRKQFEKIVATDPLHPLTPE
DKELLWHFKQECMKCPKAYPKFLSSVKWGKQEAVLATHQLLEKHDAWDRSTLDVGLAMQL
LDCHFSDENVRTVAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRRKR
IGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGEAMLHDFKKQVEVTEALQKVTKEIK
AMSADKYDVSVQVVFQLRQKLEKLQTSGLPRSFKVPYDPGLRAGSLVIEQCKVMASKKKP
LWLEFKPDDPTTRSSDTIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLSLLPYGCI
STGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDEVLNQWLGDKCVMEDKFQQAVERFVY
SCAGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPD
FLYVMGTFGKKTSPQFQKFQDVCIKAYLALRHHTNLLIILFSMMLMTGMPQLTSTEDIEY
IREALTVGKTEEDAEKHFLDQIEICRDKGWTVQFNWFLHLVLGIKQGVEKRSA
>A0A673I963|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYSMPLEAGSLE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGFRSDY
VLHVSGKLEFLFEDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIGSVLAR
KTSNPPLPLPPKKRLPTIQVRAGLFHGTELLCKTAVSSESSSRSEHVWNKTLEFDIAVCD
LPRMARLCFAIYAVMDKVKKPRSTKNTHLNKYQTIRKAGKVHYPIAWVNTMVFDYRGQLK
TGDIILHCWTSFPDELEEMLNPIGTIQTNPYTENATELHINFPEYSTQPVVFPAFDKILE
KAAEIAGASDSMTMGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSL
PKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVYCLQDMSDD
ELLQYLLQLVQVLRYEPYYDCALSRFLLERSQSSRKIGHFLFWHLRSEMFMPAVSVHFAL
ILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFGTIKTKTKQAHLKEAMMTYLCVVER
CKYMDSKMKPLWIVYNNKLLEGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLR
IVPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALD
KAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRER
VPFILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPEL
TSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A8C4WL05|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gopherus evgoodei|TrEMBL
MPPGIYCPVEFWSKEENQTIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVRDPEVNDFRAKMRQFCEEKAVKRQQLSWMTWMEYNFPLQLEPLAKGPRT
GPLRIPNKNIFVNVKFESGGESFTFQVSPKEFPVTLMSYAIKKQATVFRHQTVESPEDYT
LQVKGKCEYLYGNYPLYQFQYIRSCLHHGLMPHLTMVHFSSIIAMRDEQTNCTAHTPKMV
SKPPPLPKKKPTHESLWSLNQPFYIELVQGSKVNADERMKDCPIAWVNVMLFDYKDQLKT
GECCLHMWSSFPDEKGELLNPMGTVQSNPNTESAAALVICFPSVTPHPVYYPSFEQLLEL
GRNGEYTRAASEDPEEKQQLREILERRSHTELYEHEKDLVWKMRYEIRDQYPEALAKLLI
ITKWNKHEDVAQMISLLRSWPELPVLNALELLDFSFPDRYVGSFTINSLKKLTDDELFQY
LLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPAVALRFGLILEAY
CRGSNYHMKVLMKQGEALNKMKALNDFIKVSSQKATKPQAKEMMHVCMKQETYLEALSNL
QCPLNPTVILAEVCVDQCTFMDSKMKPLWIVFNNEEAGGRGVGIIFKNGDDLRQDMLTLQ
MIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVLHSDTIANIQLNKSNMAATAAFNK
DALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDF
GHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTTNSEKFERFRDYCEKAYMILRCHGL
LFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVN
WLAHNVSKDNRQ
>A0A7K5M7M9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cardinalis cardinalis|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHSTSSSFSSMELIPIEFILPTSNKHTKAPEMMLLD
IAGNCTVEQMKAQIWMRAIETSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A4W6BVU8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLQH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYCKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLH
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLSDLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYQDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKDWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLSDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A4W6CG33|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MPPGKYGMQEEWETEGVQEIVMDFLLPTGIFLKFPVSRNDTIQNIKRMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEETRRISDVRPFMGVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPQC
GNTKTKNIKKIFINVKFEACDESFMLQQDPQDHPVVLMRSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGKHPLCQFKYIFSCLRNGQNPYLTMVHHSTISKYQEDQGRMCSQVYKSR
SLSRPPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPPLDKVLRNGDASISTKEEYMKLKEIMDNKNYTEFFEDEKELLWKLRAEVRDR
YPESLSKLLLITKWNKREDVVQMVSLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLR
KLSDGELLQYLIQLVQVLKYESYLDCDLTTFLLERKTQDHVPSQPFGKYPPHQNEALADD
LKLCIRQESYLEALSDLLSPLNPSIILAEICADKCRFMDSKMKPLWLMYKNHFTQGDMVG
IIFKNGDDLRQDMLTLQMIQLMETLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIA
NIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIADRH
NDNIMIRETGQLFHIDFGHILGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFER
FREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEDEALKNF
KVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A669DI57|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
GNSKSQVPREESRRRRRKKAITSSCSNSMDQITVEFVLPTAARGGSGSDTLQLDVAGNWT
VEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDCIRYWR
ALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPRRI
ELSERDPKLYSMDPWVTCKPLPEHLLSKINNGHILVVIHIGTASQTIKVSIDDTPTLVLV
SFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLKNGEEIHLV
LEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVL
GIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNIKIKDLPKG
ARLNLQVICGKQPQIPNSKGSSYQESTAGSSSLDGKSRLLYYVNLLLIDHRSLLRQGEFI
LHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDWA
VGGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHECMRVPRAYPK
LLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETL
EDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSKHYQQ
RYAVLLEAYLRGCGENMLQDFRKQVDMTEALQKVTREIKTMSADKYDVTPQVVFQLRQKL
ENLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADSTTLSKDPIGII
FKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIANI
QQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDN
IMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQD
VCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQ
IEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A669E998|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKSKNIKKIFINVKFEASDVSSSVDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQVN
GRWDFIYGKHPLCQKLCENATNCCFLCECCEFLFSVVCLRSSSASKPHVLPPSNHYCVSV
VPLQLVVQAGLFHGSELLCKVVTSSEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYG
VIEKTKKPRGTKKKNKKAVSDCPIAWVNTMVFDYKDQLKTGEFHLSTWPDLLNPMGTVEK
NPNVDSAAELLIHFPNIRPHPLYYPPLEKVPSPKRLHKTYFKLKEIMDNKNYTEFFEDEK
ELLWKLRTEVRDHYPESLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFP
DPAVRSFTIRCLRKLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLF
WHLRSETHVASVGLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTA
EDLKQCIRQESYLEALSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDM
VGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDT
IANIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGD
RHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKF
ERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALK
NFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A8C8JA91|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPRPSSGELWGMHLMPPSIQVDCLLPNGMILTLVCTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANCNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCGTIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNNSWNKLKNSCKNIFSLQLFHIDFGHFL
DHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLF
INLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWI
FHTIRQHAMN
>M3VZ77|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Felis catus|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINICDLPRMARLCFAIYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDITLHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>F8W2C2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Danio rerio|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSPDLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKIAHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYFLEKYPLSQYKYIRSCITLCRLPHLMLVSKDSLYSQLPSS
GFMAPSYSRRTPQPSPCPGGGDPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDEQQIEEHANWSISRELGYSYCLGLSSRLACDSSISQADAEQLRTLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQIYCLLKDWPLMQPESSL
ELLDCNFPDPMVREFALRCLIQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIRDRNKGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A7K8D2H6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eulacestoma nigropectus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYVELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAVPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2Y9GKL2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neomonachus schauinslandi|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTVRVPTRALLVNVKFEGSEDVPLALMACALRKKATVFRQPLVEQPEDYTLQVNGKHEYL
YGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPRTKPPPIPMKK
PSSLSLWSLEQPFRVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSVCSEPV
WKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKD
QLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAPYPVYYPTLDK
ILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQERFPEALARLL
LVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQ
YLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEA
YCRGSTHHMKVLMKQGEALSKLKALSDFVKVSSQKTTKPQTKELMHLCIRQETYLEALSN
LQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNGDDLRQDMLT
LQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAF
NKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHI
DFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRH
GLLFLHLFALMRAAGLPELSCSKDTQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTK
VNWLAHNVSKDNRQ
>A0A2Y9GQU8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neomonachus schauinslandi|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTVRVPTRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFRVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALSDFVKVSSQKTTKPQTKELMHLCIR
QETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDTQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7L1NAE4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinopomastus cyanomelas|TrEMBL
MPPGIYCPMEFWSKGENQSIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWTAWMEYNFPLQLEPMAKGLGT
GPLHMPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAVKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGRTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
VKPPPLPKKKPNYSSLWSLEQSFYVELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRTAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRHD
IRDHYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEEMGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>H9GJU9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anolis carolinensis|TrEMBL
MLPGIYCPVEFWSKEANQSIQVDFLLPTGIYLTLSVSCNATLGTIKQLVWHHAQCEPFFH
MLSDPESYVFTCINQTAERQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLISSQISLL
IGKGLHEFDSLGDLEVDDFRVKMQHFCEERAARRQQLSWKAWMEYSFPVQLEPLANGLGG
RSLLQFPNKNIFVNVKFESGGESFTFQISPKEYPATLMSYAIKKQATVFRHQKINSPEDY
ALQINGKYEYLYGNHPLYQFQYIRDCLCRGLLPHLTMVHASSISALWEEQTNGISYPIKA
ASKAPPVPKKKPMSVSLWSLEQPYSIELVQGSKVNADERMKLVVQAGLYHGHEMLCKMVS
SSEVSVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIA
WVNVMLFDFRDQLKTGECCLPMWSSFPDEKGELLNPMGTVQTNPNTESAASLVIRFPTIS
SNPLYYPTFEQILEQGKNGQSSFSMVEDPEEKQQLKEILERRSHTDLYEHEKDLVWKMRH
QIRDQFPHALAKLLVVTKWNKHEDVAQMIYLLQSWPELPVLNALELLDFSFPDRYVGAFT
VNSLKKLTDADLFQYLLQLVQVLKYESYLDCELTKFLLGRALSNRKIGHFLFWHLSAVIP
LPFYIYRLAFLVFLGCVVLLFCPRPKFHYPFIYTDIASSQKNAKPQTKEFMHTCMRQETY
LEALSNLQSPLNPSVILAKVSVELCTFMDSKMKPLWIVFNNEDAGGGHVGVIFKNGDDLR
QDMLTLQMIQLMDILWKKEGLDLRMTPYGCLSTGDKTGLIEVVMDSDTIANIQLNKSNMA
ATAAFNKDALLNWLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENG
QLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFREYCERAYM
ILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEARRHFQLKFNEALRE
SWKTKVNWLAHNVSKDNRQ
>A0A7K9TWH0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chloroceryle aenea|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTADFYHSFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQNPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKTQGLSTKASLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPVALPKHRITSD
PPGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQNS
KLPGSFRVPYDPGLRAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGESEENAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A851SIA9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Certhia familiaris|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSQEVQEFQQQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDQVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIGTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C4MCZ4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Equus asinus asinus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>G3VA95|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sarcophilus harrisii|TrEMBL
MCLSFIMPPAMADNLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISNIKQMLW
KQAHNYPMFNLLMEIESYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKVITRNCDPGE
KLDSKIGVLIGKGLHEFDALEDPEVNEFRSKMRQFSEEKIQSLVGLSWIEWLKHTYPPEQ
EPSIPENLEDKLYGGNLVIAVHFENCQDVFSFQVSPNMSPIKLNELVVRKRLTIHGKEDE
VDPYDYVLQVSGRLEFVFGDHPLIQFQYIRNCVMNRTLPKLTLVECCNIKKMFEQEMIAI
EAAINRNSSNLPLPLPPKKTRLISNVWDNTQPFQVILVKGTKLNTEESVKVHVRAGLFHG
TELLCKPVVSSEISGRNDHVWSEPLEFDINICDLPRMARLCFAVYAVDKVKTKKSTKTIN
PSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDIILHSWSSFPDELEEMLNPMGTVQT
NPYFENATTLHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSGNVSSRGGKKFHAVLKEI
MERDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWPKL
PPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFML
DRALANRRIGQFLFWHLRSEVHIPAFSVQFGVILEAYCRGSVGYMKVLSKQVEALNKLKT
LNSLIKLNAVKLNKAKGREAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDS
KMKPLRIVYNNKVFGGDPLGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGC
LATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGFRQCCEDAYL
ILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRE
SWTTKVNWMAHTMRKDYRS
>A0A7J8KEG4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rousettus aegyptiacus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRVPSRALLVNVKFEGSEESFTFQVSSKDVPLSLMACALRKKATVFRQSPVEQPEDYA
LQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPRTKPPPIPMKKPSSVSLWS
LEQPFCIQLIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVNVCSEPVWKQRLEFD
INVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLTLFDYKDQLKTGECC
LYMWPSVPDEKGELLNPTGTVRSNPNTESAAALIICLPEVAPHPVYYPALDKILELGRHG
EHGRFTEEEQLQLREILERRASGELYEHEKDLVWKMRHEVQERFPEALARLLLVTKWNKH
EDVAQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQV
LKYESYLDCELAKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHH
MKVLMKQGEALSKLKALNDFVKVSSQKSPKPQTKELLHLCMRQETYLEALSHLQSPLDPS
TLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSEGSVGIIFKNGDDLRQDMLTLQMIQLMD
VLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNW
LKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGN
FKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLF
ALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNV
SKDNRQ
>A0A3B3CSB2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias melastigma|TrEMBL
MHPGIYGMLEEWEDGEQEINMDFLLPTGIFLKFPVSRNDTIKHIKEMVWRNARSEALFSG
LGDPDGYVFTCINQTAEREELEEEFRRIRDVKPFMCVLRLVAREGNRQEKLTNTQISLLI
GKGLHDFETQKNHEVNEFRTKMRAFCEEKALERQNLPWQRWLEYSFPCDLEPCRTPSGFG
SVKIKSSKIFINVKFEASDESFMLQQDCHDLPVALMKSALKKKATVFRSLRQEPEDYILQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPQLTMVHHSTVSRFQEEQSRMCNQMFKTRSL
SRPPPLPLKRQNTSSLWSINEPFYIQLLQGSRVNADEGMKLVVQAGLFHGSDLLCKVVTS
LDVTVCSEPMWDQKLEFDINVSDLPRMSRLCFALYAVIEKTKKPKSTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSMWPSVPDDKSDLLNPMGTVEKNPNVESAAGLLIRFPNIRP
HPLYYPSLEKLMDFEKNGDVVYTPKDEHLKLKEIMDNKHYTEFFEDEKDLLWKLRTEIRE
HYPESLSKLLLITKWNKREDVVQVVSLLKKWPDLPAIHALELLDYSFPDPAVRAFTVRCL
RKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASV
SLRFGLILEAYCRGNIHHIKILNKQNEALAKMRALSDFVKSGSQKMTVEDLKLCIRQETY
LEALSDLLSPLNPSIILTDICADKCRFMDSKMKPLWLMYKNPSSPGDMVGVIFKNGDDLR
QDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSA
ATAAFNKDALLNWLKSKNPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYK
ILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTEEEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDNRP
>A0A851UC12|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Elachura formosa|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWQQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRSRMCQFCEEKAAKRQQLGWAAWMEYNFPLQLEPVAKGFGA
GSLHIPTKNIFVNIKFQSGGESFTFQISPWEFPLTLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHFSAIIAMRDEQSNGIASAPKAP
ARPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGDQPRAAPEDSEERLQLKEILERRSHTELYEHEKDLVWKMRFD
VRDLYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGGGVGI
IFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIAN
IQLNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERF
RGYCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFR
LKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C6XVF3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Naja naja|TrEMBL
MPGMPPGMYCPPEFWSKESNYTIHVDFLLPTGIYLPLPVSCHASLAAIKKVVWHQAQYEP
FFQMLSAPDSYVFTCINQAAELQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLLNSQI
SLLIGKGLHEFDSLANPEVDNFRLQMQDYCEQRAAQRQQLSWKDWMEYSFPVQLEPTLSG
LGKRPSLPVPGKTIFVNVRFQSGGESFTFQISLKEFPITLMSYAVKKQATIFRHQRVSPV
DEYTLQVNGKHEYIYGEYPLYQFQYIRECLHRRFVPQLIMVHRSSLLSLREEQSNGLGHP
PKTALKLSPGPKQKLTCVSLWSLDQPYYIELLHCSNVNADEGMKLVVQAGLYHGHEMLCK
MMTSTEANVCSEPAWDQTLKFDIHVCDLPRMARLCLALYSVVEKAKKARSTKKKSKKADC
LLAWVNVMLFDYQDQLKAGECVLPMWSAFPDEKGELLNPTGTIQTNPNAESAATLFIRFP
GISLYPIYYPSMRQILEKGQNGHCAYGTGEDPEEKQQLKEILERRSCIELYEHEKDLVWK
MRYQIRDQHPGALAKLLMVTKWNKHEDVAQMIFLLQSWPELPVLNALELLDFNFPDPHVS
RFTVNSLKKLTDAELFQYLLQLVQVLKYQSYLDCELTKFLLGRALSNRKVGHFLFWHLRS
EMHFPSLALRFGLILEAYCRGNADHIKALMKQSEALNKLKALNDLIKVSAQKNTKPQTKE
FMHTCMRQETYLEALSQLQSPLDPRIFLARVSVELCTVMDSKMKPLWIMFNNGEAGGHST
GLIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKMGLIEVVMNSDTI
ANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDR
HSDNIMVRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFE
RFRDCCETAYMILRGHGLLFLHLFSLMKAAGLPELSCSKDIQYLKDSLALGKTDEEARKQ
FHLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A4W5QM27|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MPPRPSSGELWGMHLMPPSIQVDCLLPNGMILTLVCTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANCNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCGTIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQVLQTTGNASFKINESCFAACAASRPMAGSKLK
NLRFNS
>A0A287CTZ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ictidomys tridecemlineatus|TrEMBL
MPLGIDCLMKFWTEEEKNQSAVVDFLLPTGIYLSFPVSHNANLSTIKQMLWHEAQNEPLF
HVLSDPKAYVFTCVNQTAEQQELEDEQQRLCDVRPFLPMLHLVTREGDRMEKLINSQISL
LIGKGLHEFNCLQDPEVNDFRTKIHQFSEEAAACWQQLGWEAWLQYSFPLQLEPSTRCCV
NSNTSQISNPDLLVNVKFEGSRESFTIQVSTKDIPLAMMACALQKKAKVYQNLTMEQPED
YVLQVNGRHEYLYGSYLLCQFKYICSCLHSGQTPHLTMVHSSSILAMRNEQSKPAPQVQK
PHTKPPPIPMKKPSSMPLWSLGQPFCIELIQGSKIIADEQMKLVVQAGLFHGNEMLCKTM
SSLEVSMCSEPMWKQHLEFDINICDLPLMARLCFALYVVMEKAKKAHSRKKKSKKVDCPI
AWANLMLFDYKDQLKTGELYEKGDLLNPMGTVHSNPNTESAVTLVIYLPEVAPHPVYYPA
LEKIIELGLHGEHGPTTKEEKLQLQGILEQRGLGELYEHEKDQVWKMQHEVEEHFPEALA
HLLLVTKWNKHEDVALMLYLLCSWPELPVLNALELLDFTRCWQSGDCHVGSFAIRSLRKL
TGVPLFQCLLQLVQVLKCKSYLDYELTQFLLNRALANRKIGHFLFWHLCSEMHVPSVDLH
FVLIMEAYFRGSTHHMKVLMKQAEALSKLKALSNFVKVSSQKTTKPQTKELMHLYMRQDT
YLEALSHLQSPLDPSTMLAEVYVERCTFMDSKMKPLWIMYSSEEADSGDSVSIIFKNGDD
LRQDMLTLQMIQLMDALWKQEGLDLRMTPYGCLPTGDCMGLIEAVKHSDTIANIQLNQSN
LAAMAAFNKDALLNWLKSKNPGEAEGTADEAGSGPLNVDAVVMILSQDTQVLGKTEEEGL
KHFWVKFNEALRESWKTKVNWLAHNLTKDNRQ
>A0A3Q1BM58|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amphiprion ocellaris|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESCPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYQDILVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAADAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A8C7V0H6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MPPRPSSGELWGMHLMPPSIQVDCLLPNGMILTLVCTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKYVRSCIMLGRMPNLMLMAKDSLYSQLPIDTFTMPSYARRISTATPYM
NGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQLCDNVNTQRVPC
SNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEETPCLELEFDHFSNPVKFPDM
PAIEEHANCNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPLSEITEQEKD
FLWRHRHYCGTIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNFPDP
MIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFW
HLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLKQEKKDEAQK
VQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWENPDMM
SELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIE
VVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRSCAGYCVATF
ILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQ
ECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALD
KTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>I3MAN9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ictidomys tridecemlineatus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSLGA
GNASRLPSRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRRLLVEQPEDY
TLQVNGRHEYLYGSYPLCQFQYICSCMHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKP
RTKPPPIPVKKPSSVSLWSLEQPFCIDLIQGSKVNADERMKLVVQAGLFHGNEMLCKTVS
SSEVSVCSEPVWRQRLEFDINVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIA
WANLMLFDYKDQLKTGERCLYMWPSVPGGPRTGSPTTTSVPQLQLREILERRGSGELYEH
EKDLVWKMRHEVQERFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFS
FPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHF
LFWHLRYSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQK
TTKPQTKELMHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSS
EEAGSAGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLI
EVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVA
TYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQG
KTSNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALG
KTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8B9NSS4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Apteryx owenii|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHTY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEERIQSLVGVSWMDWLKHTYPPEQEPVIQE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRTTTVHVRAGLFHGTELLCKTIVSTEISGRSDHVWNEILEFEINV
CDLPRMARLCFAVYAVMDKVKTKKSTKAMNPSKYQTIRKAGKVHYPVAWVNTMVFDYKGQ
LKNGELILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIRFQEYSKQPINYPPFDKI
LEKAAEIARSSDNAAMAGRGGKKFYVVLKEIMERDPLSQLCENEMDLIWTLRYDCRENFP
QSLPKLLLSLKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLKQM
SDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQMLFWHLRSEVHIPAVSVQ
FGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNA
YREALSDLQSPLNPSVILSELHVEKCKYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDL
RQDMLTLQILRLMDVLWKEAGLDLRILPYGCLATGDHSGLIEAVSSSETIADIQLNSSNV
AAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKN
GQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAY
LILRKHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALR
ESWTTKVNWMAHTVRKDYRS
>A0A087XMM9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia formosa|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
YFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDGINDQEVKDFRSKMFRLSEEKMQRMQMMTCNEWLQACFSPQLEPA
ALTTTTDGLNDPPAELKVIIHFDQSQDSTSLKVSSSWTPSELMEMAVKKWLITHAPEEEE
WSGQYVLRVSHCLEFLCGDHPLIQYKYIRTCLQAKEPPHLTLVHTSTIKEMFDKEMSAIS
AVVSRKSSNPPLPLPPKRRVPTQVQTCVWDVSSSFRIVLVKGSKVNAEESAKVQVRAGLF
HGTELLCKPVVSSETSGRSEHTWRDNALEFEISISDLPRMTRLCFAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSPFPIVFPPFDKILEKAAQIARASDSMSIGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHDDMAQLQALLQI
WPKLCPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAERNRKIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALT
KLKSVNELIKLGTLKNARSKTKEAMLTKEAMITCLRQSGYSEALSDLSSPLNPSVLLSDI
SVEKCRYMDSKMKPLWIVYNNKLLNGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEEN
LDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTNSNVAATAAFNKDALLNWLKERNSG
DALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEDAYLILRKNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C5R819|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptobrachium leishanense|TrEMBL
MEVQRLHWERRVPVNHDIQRQDTVLFEIEIASGMELDNNDQPVVLRDENKRRRRKMRPHS
ATINIFSMELIPIEFILPTSHKNNKAPDTILLEIAGNCTVEQMKAQVWMNAIEKSHNSDF
YHRLAPDQFLLQYQKKGQWYEIYDKHQVIQTLDCIVYWKVLKKTVGKIYVVQKEKNSDET
LEYQKQLNYLIGYDVTDVSNVHDDELEFTRRRLVTPRMIELAKRDARLYSMDPWVTSKFL
PEYLGRKISSNTIFIIIHKGMTSHTVKVSINDTPDEILQSFFTKMAKKKSLLDISEENSE
LDFVLRVCGRDEYIFGNTPIKDFHWIRQCIKNGDEIHLVLDAPPDPTDDKVQKEEWPLVD
DCTGVTGYHEQLTIEEKDHEKIFTISLWDCNRKFRVKVIGIDIPVLPRNSELTVFVEANI
QHSQQLLAQKRTTSKPFTEEVLWNTWLEFDIKIKDLPKGALLNLQIFCGKAVTPSNKTSL
QSPDSSSSDSKCKNQLLYYVNLLLIDHRFLLRQGEYVLHMWKIPGKGEEQGSINADKLTS
ATNPDKDTSMAISISLDKYCHPVALPKNKSVVDAEQDRSRGEMPNQLRKQLEEIMATDPL
HPLTPEDQELLWHFRYEIIKHPEAYPKLFTSVKWGQQEIVTKTYQLLSKREAWDDCSLDV
GLTIQLLDCNFSDENVRAMAVQKLDSLPDDDVLHYLLQLVQAVKFEPYHDSSLSRFLLKR
ALRSKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGTAMLKDFMKQVQVTELLHK
VTMEIKSLSAEKYDVTSQVITQLRQKLEKLQGSKLPESFRVPYDPGLRAGLLMVEKCKVM
ASKKKPLWLEFKCADPTALTNETIGIIFKHGDDLRQDMLILQILRIMGSIWEAESLDLCL
LPYGCISTGNKIGMIQIVKDATTIAQIQQSTVGNTGAFKDEVLSQWLKEKCPLEEKYNAA
VERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVP
FVLTPDFLYVMGTSGKKTSLYFHKFQDVCVKAYLALRHHSNLMIILFSMMLMTGMPQLTS
KEDIEYIRDSLTVGKNEESAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C2TT96|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coturnix japonica|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIILGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMFITDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSTRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRNFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNHLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8B9V0W1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas zonorhyncha|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPYCTSSNLSSMELIAIEFILPTSNKHTKIPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYQAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHDSPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A670YQH2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pseudonaja textilis|TrEMBL
VCFRDRMPPGMYCPSEFWSKESNYTIHVDFLLPTGIYLPLPVSCHASLAAIKKVVWHQAQ
YEPFFQMLSAPDSYVFTCINQAAELQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLLN
SQISLLIGKGLHEFDSLADPEVNDFRVQMQDYCEQKAAQRQQLSWKDWMEYSFPPLNSLS
PCYGLRKLTFCLHIFFLDWQESFTFQISLKEFPITLMSYAVKKQATIFRHQRVSPADEYT
LQVNGKYEYIYGEYPLYQFQYIRECLHRRFVPHLIMVHRSSLLTLREEQSNGLGHPPKTN
WIGSSLGWINLLPSPIYLLFFQLVVQAGLYHGHEMLCKMMTSTEANVCSEPTWDQTLKFD
IHVCDLPRMARLCLVLYSVVEKAKKARSTKKKSKKADCPLAWVNVMLFDYQDQLKAGECV
LPMWSAFPDEKGELLNPTGTIQTNPNAESAATLFIRFPGISLYPIYYPSMRQVRLLKEIL
ERRSCIELYEHEKDLVWKMRYQIRDQYPGALAKLLMVTKWNKHEDVAQMIFLLQSWPELP
VLNALELLDFNFPDPHVSRFTVNSLKKLTDAELFQYLLQLVQVLKYQSYLDCELTKFLLG
RALSNRKIGHFLFWHLRSEMHFPSLALRFGLILEAYCRGNADHIKALMKQSEALNKLKAL
NDLIKVSAQKNTKPQTKEFMHTCMRQETYLEALSHLQSPLDPRIFLARVSVELCTVMDSK
MKPLWIMFNNGEAGGPNTGLIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCL
STGDKMGLIEVVMNSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMVRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTSNSEKFERFRDYCERAYMILRGHGLLFLHLFSLMKAAGLPELSCSKDIQ
YLKDSLALGKTDEEARKQFHLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A672ZWP3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
MPPGKYGMQEEWEKEGDQGIMMDFLLPTGIFLKFLVSRNDTIKSIKKMVWKNARSEALFA
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRMFCEEKALDRQRLPWQQWMEYSFPCDLEPCCSPPEC
GNAKSKNTKKLFINVKFEASDESFMLQQDPQDLPVALIRSALKKKATVFRSVRQEPEDYT
LQVNGRWDFIYGSHPLCQYKYIFFCLRNGQNPHLTMVHHSTISKYQEEQGQMCNQVFKSR
SLSRPPPLPLKKLVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQKLEFDINVADLPRMS
RLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDD
KSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRQHPLYYPPLEKVLDPKHFCTGITSLKEIM
DNKNYTEFFEDEKELLWKLRSVVRDHYPESLSKLLLITKWNKREDVVQMVGLLRNWPELP
AIHALELLDYSFPDPAVRSFTIRCLRKLSDGELLQYLIQLVQVLKYESYLDCDLTTFLLE
RALSNRRIGHFLFWHLRSEIHVASVSCVFGLILEAYCRGNIHHIKLLTNRYLPTLSKSGS
QKMTAEDLKLCIRQESYVEALSDLLADKCRFMDSKMKPLWMMYRNPFVQGDMVGIIFKNG
DDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNS
SNSAATAAFNKDEKLEKAIEEFTLSCAGYCVATYILGIGDRHNDNIMIRETGQLFHIDFG
HFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTL
FVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNW
MMHSLAKDNRP
>A0A6P6BZ44|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pteropus vampyrus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQFEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLSLMACALRKKATVFRQSLVEQPEDYA
LQVNGRHEYLYGSYPLCQFQPSSVSLWSLEQPFCIQLIQGSKVNADERMKVVQAGLFHGN
ETLCKTVSSSEVNVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKS
KKADCPIAWANLTLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAAL
VICLPEVAPHPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRASGELYEHEKDLV
WKMRHEVQERFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDSSFPDRH
VGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELAKFLLDRALANRKIGHFLFWHL
RSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPQT
KELLHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSE
GSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHS
DTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGI
GDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSE
KFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEA
LKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A850ZG28|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tichodroma muraria|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQVPTKSIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSS
SEVSVCSEPVWRQRLDFDISICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C6QUS2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nannospalax galili|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREAMLVTIKHELFQEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILSVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPTD
SFTMPSYSRRISTATPYMNGETPTKSLWVINSVLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIHIPDLPRAARLCVSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRALCTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A6J2CDY1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zalophus californianus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECFKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVDCLRQMRFLLERALANRRIGQFLFWHLRSEVHIPAV
SVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMHTCLK
QNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNG
DDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNS
SNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMV
KKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCE
DAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDE
ALRESWTTKVNWMAHTVRKDYRS
>A0A8C3KBQ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calidris pygmaea|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMTKGLGA
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGDQPRAALDDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTPFLFMFRYLLQLFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYC
RGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHVCMKQETYLEALSHLQ
SPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQM
IQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKD
ALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFG
HFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLL
FLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNW
LAHNVSKDNRQ
>A0A7K7ZVG3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Melanocharis versteri|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQVWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIVATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEDKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIGYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K8I082|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aleadryas rufinucha|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKRTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVIQKQKPSEEVQEFQRQLNDLIGYDVTDISNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNVQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K8V659|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ciccaba nigrolineata|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIESLHKVTMEIKSVSAEKYDVTSQVISQLRQKLEKLQSS
NLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGSSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6J2UWA6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chanos chanos|TrEMBL
MPPGVYGMQDVWENEGREQVTVDFLLPTGIYLSFPVSHSDTIGAIKKMVWKNARSEPLFS
ALGDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPVLRLVAREGNRVEKLINTQISLL
IGKGLHEFDAQKNHEVDEFRTKMRLFCEERALERQLLPWYQWMEYSFPCDLEPCSIVTQS
GKNRNVKKIFVNVKFEASEESFMLQLEPHDLPVTLVKSALKKKATVFRPVKQEKPEDYTL
QVNGRWEFIYGKYPLCQFKYIFSCLHGGLTPHLTMVHHSTIVKYQEEQGIINNHISKSRS
SSKPPPLPLKKQNTSLLWSIQEPFYVQLVQGARVNADEGMKLVVQVGLFHGSELLCKVVT
SNEINVSSEPLWDQKLQFDIGVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPLA
WVNTMVFDYKDQLKTGEFWLSTWPSVPDDKGDLLNPMGTVERNPNIDSTAGLLIRFPNIR
PHPLYYPPLEKVGRTNGERVATTKEEHLKLKEIVDNKNYTEFFEDEKELLWKMRSVVREK
YPESLSKLLLITKWNKHEDVVQMVCLLRKWPDLPALHALELLDYSFPDPHVRSFTIRCLR
KLRDDELFQYLLQLVQVLKYESYLDCDLTSFLLERALSNKRIGHFLFWHLRSEMHVSSVS
LRFGLIMEAYCRGSIYHMKSLMKQNEALNKMKALNDFVKSGCQKASRSQTTEEMKVCIKQ
DTYLEALSDLLSPLNPSIILSEICADNCKFMDSKMKPLWLMYKNKWMQTDTVGIIFKNGD
DLRQDMLTLQMIQLMDVLWKTESLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNS
NSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIR
ENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQ
AYKILCRNGILFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEA
LRESWKTKVNWMMHSFAKDNR
>A0A6J2VT48|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chanos chanos|TrEMBL
MEQQISDDEPPVVPREENKRRRRGKMKAFTSNSSVDMDHIAVEFVLPTTNKISKCPDTLQ
LDVAGNWTVEQVKAQLWLRAVAANICPEFYQKYNPDHCILLYQKKGNWYEIYDKHQVFQT
LDCIRYWKALKKEMGKIHLTIRSQPTEESIQYQKFLNHLIGYDVTDVSNVHDDELEFTRR
KLLTTRKIELSDRDPKLYSMDPWITTKPLPEYLMSKISNNHILLVIHRHTSSQTIKVSID
DTPVQVLRSFFTKTANKKALFGIPENVSESDFVLRICGREEYIFGNYAIKNFHWVRQCLK
NGEEIHLVLESPPNPEHDVVQKEDWSQVDDCTGVAGTHEQLTIDEKDHEKVFTISLWDCN
RKFRVKVLGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTSSKPFTEEVLWNTWLEFNI
KIKDLPKGARLSLQVSCGKAQTQTSRDNSNYDSKTKSRLLYYVNLLLVDHRSLLRQGEFI
LHMWKMPEKSEDNSSVNADKLTSATNPDKTSSMAIAIILDKYCYPVALPKSRDSREGSDV
EGERGQREMPNHLRKQFEQIIATDPLHPLSAEDKELLWHFRQECLRNPRAYPKFLGSVKW
GKQEAVMITHQLLEKSNTWDRSPLDVGLAMQLLDCHFSDANVRSMAVRKLETLGDDDVLR
YLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILE
AYLRGCGEAMLQDFRKQVEITEALQRVTREIKAVSAEKYDVSAQVVFQLRQKLENLQISG
LPESFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGVIFKDGDDL
RQDMLILQILLIMESIWETESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGN
TGAFKDEILNQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESG
NLFHIDFGHILGNYKSFMGISKERVPFVLTPDFLYVMGTTGKKTSPLFPKFQDICVKAYL
ALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEEEAQRHFLDQIEICRDK
GWTVQFNWFLHLVLGIKQGVEKRSA
>A0A3Q2HEW8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Equus caballus|TrEMBL
MCFNFMMPPAMADSLDIWSVDSQIVSDGSIRVDFLLPTGIYIQLDVPREAPISYIKQMLW
KQVCDYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRVKMRKFSEEKIQSLVGLSWMDWLQQTYPPEH
EPSNLENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIRGKEDE
VSPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVNCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYTNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRDDLDR
AIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERV
PFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELT
SVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3Q2KXE4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Equus caballus|TrEMBL
MCFNFMMPPAMADSLDIWSVDSQIVSDGSIRVDFLLPTGIYIQLDVPREAPISYIKQMLW
KQVCDYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRVKMRKFSEEKIQSLVGLSWMDWLQQTYPPEH
EPSNLENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIRGKEDE
VSPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVNCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYTNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQDSLALGKSEEEALKQFKQKFDEALRESW
TTKVNWMAHTVRKDYRS
>F6VFI8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Equus caballus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A672R5W2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPGVYGMQDVWEREGWQQVNMEFLLPTGIYLNFTVTSSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWDQWMEYNFPCDLEPCSVVAQS
GKSCSDKKIFVNVKFEGSEETFVLQQGPQDLPMFLKQNALRKKSTVFRSAKQEKPEDYAL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDISASDLPRMSRLCIALYGVIEKTKKRPTKKKNKSSDCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGLNGEKTVATKEEHLKLREIVDNKNYTEFFEDEKELLWKLREVVRQ
RYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHARSFTIRCL
RKLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVSSV
SLRFGLILEAFCRGSIFHLKNLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIK
QDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDTLGIIFKNGDDL
RQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNS
AATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRET
GQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAY
KILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLMDSLALGKSEEEALKNFKVKFNEALR
ESWKTKVNWMMHTFAKDNR
>G3SUK0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Loxodonta africana|TrEMBL
MDLENAEPPVVLRADNFRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRNSKTRETVLLH
VAGHGNVEQVKAQVWLRALETSVAADFYHRFGPDHFLLLYQKKGQWYEIYDRHQVVQTLD
CLRYWKMLHRSPGQIHVVQRKALSVETVAFQQQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLSKKIANNCIYIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLSHRRTSPKPFTEEVLWNVWLEFGIKI
KDLPRGALLNLQIYCGKAPALSGKASAETPGSEPKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKESSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKYPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQRVTIDIKSVSVEKYDVSSQVISQLKQKLEDLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSKETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPLEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGISKERVPFVLTPDFLFVMGTSGRKTSPHFQKFQVSCLAFHHLQ
DVCARAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLD
QIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A672MI27|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQS
GKSHSGKKILVNVKFEGSEETFVLQQDPQDLPMFLKRNALRKKSNVFRPAKQEKPEDYTL
QVNGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKFQEEQGGLSNQVSRTRA
QSKPPPLPLKRVRRHFYTGTRSVINRGTTFHVSLVAYVVDFNLCELDLQCDVLDCPLAWV
NTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPH
PLYYPPIEKLNELGMNGEKVVATKEEHLKLREIVDNKNYTEFFEDEKELLWKLREEVRQR
YPESLPKLLLITKWNKHEDVAQMVGLLRKWQDLPAIHALELLDYSFPDPHVRSFTIRCLG
NLRNDELFQYLLQLVQVLKYESYLDCDLTCFLLERALSNKKIGHFLFWHLRSEMHVPSVS
LRFGLILEAYCRGSIFLIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQ
DTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKDKYDHVGIIFKNGDDLR
QDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSA
ATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETG
QLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFREYCEQAYK
ILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRE
SWKTKVNWMMHSFAKDNR
>G3PUB9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gasterosteus aculeatus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLVTVKHDLFKEARKYPLHH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSVELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SCPVKYPEMTIIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGIKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A7K4KJH5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crypturellus soui|TrEMBL
MPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWQHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRIKMRQFCEERAAKRQQLSWAAWMEYNFPLQLEPLAKGFGT
GPLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIMAMRDEQTNCIANPPKLA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSIAS
HPVYYPSFEQLLELGRNGEQPRSALEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
VRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDGELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVEQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALAKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A5E4CG33|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Marmota monax|TrEMBL
MLWHEAQNEPLFHMLSDPEAYVFTCVNQTAEQQELEDEQQRLCDVRPFLPMLRLVTRQGD
RMEKLINSQISLLIGKGLHEFDCLQDPEVNDFRTKMRQFSEEEAARRQQLGWEAWLQYSF
PLQLEPSTRSWGDSNTSQISNPDLLVNVKFEGSRESFIIQVSTKDVPLVLMAGALQKKAK
VYQHLTMEKPEDYVLQLNGWHEYLYGSYLLCQFKFNFTLSSQYICSCLHSGLTPHLTMVH
SSSILAMRDEQSKPAPQVQKPHTKLPPIPMKKPSSVSLWSLGQPFCIELIQGSKINADEQ
MKLVVQAGLFHGNEMLCKTMSSLEVSVCSEPMWKQHLEFDINICDLPRMAQLCFALYAVM
EKAKKARSSKKKSKKVDCPIAWANLMLFDYKDQLKTGELCLYMWPSVPDEKGDLLNPMGT
VHSNPNTESAVTLVIYLPKVSPHPVYYPALEKKLQLQGILDQRGSGELYEHEKDLVWKMR
HEVQEHFPEALAHLLLVTKWNKHEDVAQMLYLLCSWPELPVLNALELLDFSFPDCHVGSF
AIRSLQKLTDDELFQCLLQLVQVLKYKSYLDCELTQFLLDRALAN
>A0A672I5M1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salarias fasciatus|TrEMBL
MPPGKYGMQEEWEKEGEVVMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFSGL
GDPDAYVFTCINQTAEREELEEESRRVSDVRPFMCVLRLVAREGDRVEKLTNAQISLLIG
KGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERQSLPWHQWMEYSFPCDLEPCCSPPGSKT
KNTKKIFVNVKFEASDESFMLQQDPQDLPMALMRSALKKKATVFRSVRQEPEDYTLQVNG
RWEFIYGRHPLCQFKYIFSCLRNCQNPHLTMVHHSTISKYQEEQGRMCSQVYKTRSLSRP
PPLPLKKVRASVNLPQTTRHLQVLKRIQLPNHTSCPGLICVCVCSSPSQLVVQAGLFHGS
ELLCKVVTSSEVTVCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKN
KRADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVDLLNPMGTVEKNPNVDSAAGLLIRYP
NIRPHPLYYPPLEKVLTNVRLKEIMDNKNYTEFFEDEKELLWKLRAEVRDRFPESLSKLL
LITKWNKREDVVQMVSLLKKWPDLPAIHALELLDYSFPDPAVRSFTIRCLRKLSDGELLQ
YLIQLVQVLKYESYLDCDLTTFLLERALSNKRIGHFLFWHLRSEIHVASVGLRFGLILEA
YCRGNIHHIKLLTKQVINEALGKMKALSDIVKSGSQKMTAEDLKLCIRQESYLEALSDLL
SPLNPSVVLAEICADKCRFMDSKMKPLWLMYRNPLAQGDMVGIIFKNGDDLRQDMLTLQM
IQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNNSNSAATAAFNKD
ALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFG
HFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTL
FVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSDEEALKNFKVKFNEALRESWKTKVNW
MMHSLAKDNRP
>A0A3Q2WZ54|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Haplochromis burtoni|TrEMBL
MAPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLTTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYSKLDKGQIIVVIWVIVSPTNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMD
FFTMPSYARRISTATPYMNGETATKNLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLTYDMYIPEVPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHY
SSPVKFPDMSTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDGDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHDCINMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMVREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8C0JZR4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus dingo|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYCFPLQLEPSARSWGP
GTLRVPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMR
QEAYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A3B5QN21|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xiphophorus maculatus|TrEMBL
MPPGKYGTQEEWEQDGDQEIFMDFLLPTGIFLKFPVSRNDTIRNIKKMVWKNASREALFC
GLRDPDLYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNTQISLL
IGKGLHEFEAQKNHEVDEFRTKMRTFCEEKSLERQNLPWQRWMEYSFPCELEPCSSPAAG
GSSKSKHGKKLFVNVKFESSDESFMLQQDSQDLPVALMKSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGQHPLGQFKYIFSCLRNGQNPQLTMVHHCTISKYQEDQGRVCSQMYKTR
SLSRPPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKDCPIAWVNTMLFDYKDQL
KTGEFLLSMWPSVPDDKSDLLNPMGTVQRNPNVDSAAGLLIRFPNIRPHPLYYPPLDKTI
EPEMNGNTVFPSKDEYLKLKEIMDNKNYTEFFEDEKELLWKLRAEVRDYFPECLSKLLLI
TKWNKREDVAQMVGLLKSWPELPAIHALELLDYSFPDPAVRSFTIRCLKKLSDDELLQYL
IQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLKSEIHVASVSLRFGLILEAYC
RGNIHHIKLLSKQNEALGKMKALSDIVKTGSQKMTVDDLKLCIRQESYLEALSDLLSPLN
PSVILFEICTDKCRFMDSKMKPLWLMYKNPLEQADMVGIIFKNGDDLRQDMLTLQMIRLM
ENLWKKEGLDLRMIPYGCLSTGNKTGLIEVVKSSDTIANIQRNSSNSAATAAFNKDALLN
WLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLG
NFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNL
FAMMKAAGLPELSSSKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHS
LAKDNRP
>M4AAZ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xiphophorus maculatus|TrEMBL
MPPGKYGTQEEWEQDGDQEIFMDFLLPTGIFLKFPVSRNDTIRNIKKMVWKNASREALFC
GLRDPDLYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNTQISLL
IGKGLHEFEAQKNHEVDEFRTKMRTFCEEKSLERQNLPWQRWMEYSFPCELEPCSSPAAG
GSSKSKHGKKLFVNVKFESSDESFMLQQDSQDLPVALMKSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGQHPLGQFKYIFSCLRNGQNPQLTMVHHCTISKYQEDQGRVCSQMYKTR
SLSRPPPLPLKKLVVQAGLFHGSELLCKMMTSSEVTVCSEPSWDQRLEFDINVSDLPRMS
RLCFALYAVIEKTKKPRGTKKKNKKADCPIAWVNTMLFDYKDQLKTGEFLLSMWPSVPDD
KSDLLNPMGTVQRNPNVDSAAGLLIRFPNIRPHPLYYPPLDKVYLKLKEIMDNKNYTEFF
EDEKELLWKLRAEVRDYFPECLSKLLLITKWNKREDVAQMVGLLKSWPELPAIHALELLD
YSFPDPAVRSFTIRCLKKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIG
HFLFWHLKSEIHVASVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDIVKTGSQ
KMTVDDLKLCIRQESYLEALSDLLSPLNPSVILFEICTDKCRFMDSKMKPLWLMYKNPLE
QADMVGIIFKNGDDLRQDMLTLQMIRLMENLWKKEGLDLRDKLDQAIEEFTLSCAGYCVA
TYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQG
RTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELSSSKDIQYLKDSLALG
KSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A5K1VGE3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MCFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDYPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHIWENNNPFQIVLVKGNKLNTEETVKHYPVAWVNTM
VFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIKFPENKKQPYY
YPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQD
CRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAV
GCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVHI
PAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMHT
CLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSIGVIF
KNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQ
LNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDN
IMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQ
CCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQK
FDEALRESWTTKVNWMAHTVRKDYRS
>U3IGC4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos platyrhynchos|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPYCTSSNLSSMELIAIEFILPTSNKHTKIPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYQAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHDSPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A2K5Y7A8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mandrillus leucophaeus|TrEMBL
MELENYEQPVVLREDNCRRRRRMKPRSVAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVASDFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPAVSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAVGITWMSPRGLYVLKMSNMLAGAQYLKHNILRIMESIWETESL
DLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKSPTEEK
FQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINK
ERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDTCVKAYLALRHHTNLLIILFSMMLMTGMP
QLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKH
SA
>A0A8B7PYL3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hipposideros armiger|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRLPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYCHAGLSNRLARDNELRENDKEQLRSICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K8Y322|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eubucco bourcierii|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLHTPTKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWRQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAP
HPVYYPSFEQLLELGRNGEQLRAAAEDPEEKQQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGQVASLLLKQAIEEFTLSCAGYCVATYVLGIGDR
HSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFE
RFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKH
FRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8B9XIU2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus grunniens|TrEMBL
MLMSLSGGTICNFAALVLAQEGQDDWYLRSEKAGCPPGLTAPWNSGPRRRIRAWQLISCS
PRGLSELPVSRNANLSTIKKVLWHRAQYEPLFHMLSDPEAYVFTCVNQTAEQQELEDEQR
RLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHEFDSLQDPEVNDFRGKMRQFC
EEAAARRQQLGWEAWLQYSFPLQLEPSARSWGPGTLRVPNRVLLVNVKFEGSEESFTFQV
STKDVPLALMACALRKKATVFRQPLVEQPEDYTLQVNGKHEYLYGSYPLCQFQYICSCLH
SGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRTKPPPIPMKKPSSVSLWSLEQPFYIEL
IQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRM
ARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGEHCLYMWPSVPD
EKGELLNPCGTVRSNPNTESAAALVIFLPEVAPHPVYYPSLDKILELGRLGEHGRFTEEE
QLQLREILERRGSGELYEHEKDLVWKMRHEIQEHFPEALARLLLVTKWNKHEDVAQMLYL
LCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDC
ELTKFLLDRALANRRIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGE
ALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDPSTLLAEVCVE
QCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLD
LRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEA
LDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINR
ERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLP
ELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A0S7FLS4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poeciliopsis prolifica|TrEMBL
PISQDRLRHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQNFPLFPSLGEME
SHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERQLDSKIGVLIGKGLH
ELDGINDQEVKDFRSKMSRLSEEKMQRVQMMTCNEWLQACFSPQLEPAALTTITDGLNDR
PADLKVIIHFDQSQDSTSLKVLSSWTPSELMEMAVKKWLVTHAPEEEEWSGQYVLRVSHC
LEFLCGDHPLIQYKYIRTCLQAKEPPHLTLVHTSTIKEMFDKEMSAISAVVSRKSSNPPL
PLPPKRRIPTQAQTCVWDVTSTFRIVLVKGSKVNAEESAKV
>A0A5N3WA22|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Muntiacus muntjak|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C0T4B1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFE
>A0A8D2M040|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zonotrichia albicollis|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSSLPLPLPPKKRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLCK
TIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKYQ
TIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMERD
PLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPRE
ALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERAL
GNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSL
IKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKP
LWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATG
DHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLSC
AGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFI
HVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A667IKM1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lynx canadensis|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKHYPVAWVNTM
VFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIKFPENKKQPYY
YPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQD
CRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAV
GCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVHI
PAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMHT
CLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIF
KNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQ
LNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDN
IMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQ
CCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQK
FDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C4D8T6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHDLFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMTIIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNEQLRQVCNRDPL
SEITEQEKDFVWRHRQACVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8C4I7Z9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MPPGKYGMQEEWEKEGDQGILMDFLLPTGIFLKFPVSRNDTIKSIKKMVWRNARSEALFS
GLGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPMS
GSMKSKSTKKIFINVKFEACDESFMLQQDPQDFPVALMRSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGKHPLCQFKYIFSCLRNGQNPHLTMVDHTTISKYQEEQGRMCSQVYKSR
SLSRPPPLPLKKLVVQAGLFHGSELLCKVVTSPEVAVSSEPLWDQNLEFDINVADLPRMS
RLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDD
KGDLLNPMGTVEKNPNVDSAAGLLIRFHNIRPHPLYYPPLDKISDVEKNGDAGIPTKEEY
MKLKEIMDNKNYTEFFEDEKELLWKLRTEVRNHYPESLSKLLLITKWNKREDVVQMVSLL
RKWPDLPAIHALELLDYSFPDPAVRSFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCD
LTTFLLERALSNWRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIKLLTKQNEA
LGKMKALSDFVKSGSQKMTVDDLKLCIRQESYLEALSDLLSPLNPSIVLSEICADKCRFM
DSKMKPLWLLYKNPQAQGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPY
ACLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDQAIE
EFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFI
LTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFK
DIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A7K9DU23|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hemiprocne comata|TrEMBL
MPPGIYCPMEFWSKGENQSIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMRQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPIKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVESPEDYT
LQVNGKCEYLYGNYPLFQFQYIRSCQHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAP
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSNTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A674AEX5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
IELQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKHLPEYLLSKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPEDVCEGDYILRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFN
IRIRDLPKGARLSLQVNCSSHDGNKTKSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPEK
TEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYPVALPKSREGERGQREMPNHLRKQF
ESIVETDPLHPLSQEDKELLWHFREECMRHPRAYPKLLGSVRWGRQEAVLATHRLLERSS
VWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDS
ALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQ
VEMTEALQKVTREIKAMSAEKYDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGA
LVIEQCKVMASKKRPLWLQFKRADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIW
EEESLDLSLLPYGCISTGNKIGMIEIVRDATTIANIQQSVVGSTGAFKDEILNQWLRDKC
VSEEKFQQAVERFVFSCGGYCVATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSF
LGISKERVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMML
MTGMPQLTSKEDIEYIREALTVGRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIK
QGGDKRSA
>A0A667XIQ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MPPAMTDLLDMWAAHSPLAGHATDVITMDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TYPLFPALGEMEGHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQKMTWTEWLQACFSPQLENG
GGAITDGLNDRPADLKVIIHFDQSQDTASLKVSPSCTPTELMELALRKWLTTHGPEDEAR
RGQYVLRVSQRLEFLCGDHGLIQYKYIRSCTQAKESPHLTLVHTSTVKAMFEKEISAIGA
VVTRRSSNPPLPLPPKRRIPTQVQTCVWDVSSQFKIVLVKGSKVNAEESAKVQVRAGLFH
GTELLCKTAVSSESSGRSEHTWSDGTLEFDICVCDLPRMTRLCFAVYAVMDKVKKQKSTK
NTHLNKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPIGT
IQTNPYTENATALHIHFPEYSSHPIVFPLFDKVRVSGRGGKKFHIELKEIMERDPLSQLC
ENEKDLIWTLRHDCHENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLD
FNYPDQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLDRAQSNRKIG
HFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTI
KNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMDSKMKP
LWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDMLWKEASLDLRIVPYGCLATG
DRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALERAIEEFTLSC
AGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFI
HVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A673ZFD3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPAMPDDLDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFCPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQACFSPQLEPGVH
HAISVSLCVCVCCVDDNVLSLQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEEGRQAE
QYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSSVQAMFEKEISAIGAVV
NRKSSNPPLPLPPKRRGPSVSYTLSLCRVCLSRSPYYGEPLVVVVPPPQVQVRAGLFHGT
ELLCKPVVSSESSGRSEHVWNRTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKSTKNAH
INKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPIGTIQT
NPYTENSTALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCSTMSRGGKKFHIELKEI
MERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKL
SPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLL
NRAQCNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKS
VNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEK
CRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLR
IVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALE
KAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRER
VPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPEL
TSVKDIQYLKVIGRFTWDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDN
RS
>A0A667XJV0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
YFLENSPVVLREESRRRRRKKAITPSSCASMDQITVEFVLPSAARGGSGPDTLLLEVAAN
WTVEQVKAQVWLRAVASNLCPDFYQRFSPDHCILLYQKKGSVCEIYDKHQVFQTLDCIRY
WRALKKEVGRIQLVPRPQPTDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPR
RIELSERDAKLYSTDPWLTDRPLTEHLLSKVSNGHILLVIHVGSNSQTIKVSIDDTPAQV
LASFFTKTANKKALLGIPDSVCEADFVLRVCGREEYLYGDKPVQNFHWIRQCLKNGEEIH
LVLETPPDPALDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVK
VLGIDIPSLPKNPELTVFVEASIFHGQQLLAQERTTSKPLSEEVLWNCWLEFNIRIRDLP
KGARLNLQVTAQKTQRELFSSAQTPNSKTKSRLLYYVNLLLVDHRSLLRQGEFILHMWKM
PEKSEESSSSVNADKLTSATNPDKASSMAVSVLLDRYCFPVVLPKSREAGRDAAAPDEAE
GGERGQREMPNHLRKQFEAIVATDPLHPLSPEDKELLWHFRHECMRHPRAYPKLLSSVRW
GKQEDVLITHRLLERSTAWDSSRLDVGLAMQLLDCHYSDAQVRSMAVRKLETLGDDDVLR
YLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIVQSMHYQQRYAVLLE
AYLRGCGEAMLQDFRKQVEVTEALQRVTREIKAMSADKYDVSAQVVFQLRQKLETLQSSG
LPDSFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSRDAIGIIFKDGDDL
RQDMLILQILLIMESIWETENLDLSLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGS
TGAFKDEILHQWLRDRCVSEDKKLCCVCVCVCVCVCVCVCVCVCVCAGNLFHIDFGHILG
NYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFHKFQVLEADVCVKAYLALRHHTNL
LIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQINW
FVHLVLGIKQGVEKRSA
>A0A8C0IWJ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelonoidis abingdonii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVCPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWVINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMTVIEEHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K9AXR7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dromaius novaehollandiae|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWQHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRIKMRQFCEERAAKRQQLSWAAWMEYNFPLQLEPLAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHQGLTPHLTMVHSSSIIAMRDEQTNCIANAPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVHCNPNTESAAALVICFPSITS
HPVYYPSFEQLLELGRNGEQPRAALEDPEEKLQLKEILERRSHTELYEDEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDGELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVEQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALAKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7N9CI17|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca fascicularis|TrEMBL
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPFSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDIHICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7K4IXW4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geococcyx californianus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQNEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLNWAAWMEYSFPLQLEPMTKVLGT
GPLHKPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHQGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTDSAAALVICFPSVAL
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSYTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELLQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKSLNDFVKSSSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGRGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A151M608|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alligator mississippiensis|TrEMBL
MTKSLANICSSRGPCGYDTIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAH
SYPLFHLLLEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDS
RIGVLIGKGLHEFDALPDPEVKEFRTKMRRISEEKNHSLVSLSWMDWLKHTYPPEQEPSI
PENFQDKLYGGNLVVAIHFDNCQDVFSFQVSPNINPIKLNELAIRKRLTIRGREDEEINP
SDYVLQVSGRLEYVFGDQPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCDQEMIAIEAA
INRKSSNLPLPLPPKKTRTATLTQSVWDISNPFKIILLNGNKLNTEETTKVSVRAGLFHG
TELLCKPIVSTEVSGRSDHVWNETLEFEVNVCDLPRMARLCFAVYAVMDKMKTKKSTKTM
NTAKYQTIRKAGKVHYPVAWVNTMIFDYKGQLKTGDLILHSWSSFPDELEEMLNPMGTVQ
TNPYAENATALHIKFQEYSKLPIYYPPFDKILEKAAEIAKSSDSAMAGRGGKKFYVVLKE
IMERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWTK
LPPREALELLDFNYPDQYVREYAVGCLKLMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQVLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLSKQVEALNKMK
TLNGLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHIERCKYMD
SKMKPLWIVYNNKMFGGDFVGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYG
CLATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRRHGNLFITLFALMLTAGLPELTSIKD
IQYLKDSLALGKSEEDALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8B9DPZ4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anser cygnoid|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
NFQDKLYSGNLVVAIHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEIDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRTTTSVWDVCSPFKITLLKGNKLNTEENAKVHVRAGIFHGTELLC
KTIVSTEISGRSDHIWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGEFVLHSWSSFPDELEEMLNPMGTVQTNPYI
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSIQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K5Y0D0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dromas ardeola|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIPSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVV
>A0A6F9DP17|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phallusia mammillata|TrEMBL
MAGYGYHGSAQYNMSRDEEIYDEWGYHDSVNVSVDFLLPTGIYIPLDVPRNDTIKQVKQL
LWEEAIHHPLFNQLQNQDSYTFVYITSTGIQEEITDERRHLSEFDLIHELPVLKLIQSQG
NIEEKRIIHEIHQLAGIKNENDLNVDAESRAFRKEMREEAIKVSIRRSSLHWKVLLENHY
PPTIIPHLNEKTHTRRDYGLIQLKYENTDNSYTIKVNPQWFTFDLISEAIQTWDQKAKSN
LPSTNPDDYVLKSDGKEFIVGNYQIYMFKCLRSAMVAKREKANLPPPQPPPILTMLHVAS
VRKLLPESHPGIQVQPGNYAPPVPDKRRQTCSLWQLDMQFSVRVLRAGNINANIENNKKL
VVHVGVYHGTEALCPTVYTKEPKKEMTGGEFDWDEVCFFDTNTCNLPRNSKLCITICTMS
KTKTKSATTKKKDNNQKNSMHNNATPIAYVNMTMFDFKANLKTGLYRLHCWLWPENVDSN
NLHPRGGVTMNPDTEQAPFLEILLPEYDRNPLVQYPPQEKVLEQAAFETSTSSSSIYPSP
SKSHIAQLAAIVEKDRFDDLFDNDKNLLWYLRLDCRENWPEALSKVLCAVKWNNYKNVAL
AQAMLGAWPPLEPDRAMELLDGQFADEKVRDFAVRCLKQLRDDELQSYLMQLVQVLKFDS
YLNSSLVRFLLERAWNNRKIGHFLFWHLRAEITNTTLNLRFSLILEAYLYGNIPHMKMLY
KQFDALNKMRALNERVKSQEFSQKDVKVRARKALQETANQESFAEALSYFEDPLEPNVLL
GKPIIEKMKVMNSKMRPLWLVFQDAEETVQKHRSVIYKNGDDLRQDMLTLQIISIMDMLW
KADGLDLRMIPYGCLATGGISGMIEVVTESNTIANIQKSKTGKMHSAFRHQTLFEWIEDK
NPTKPELDQAIENFTYSCAGYCVATYVLGVGDRHSDNIMVREKGQLFHIDFGHILGNFKS
KYGIKRERVPFVLAHDFVHVINKGKTNAKEEFQYFRKLCDRAFCILRKKGHLFITLFALM
LHSGLPELTSLNHLEYLRETLALHLTEEKAIQQFRNKFNKALTDAWSTSINWFFHNVAKD
NK
>A0A099Z991|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tinamus guttatus|TrEMBL
SRMPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWQHAQYEPL
YHMLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQIS
LLIGKGLHEFDSVQDPEVNDFRIKMRQFCEERAAKRQQLSWAAWMEYNFPLQLEPLAKGF
GTGPLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIANPPK
LAAKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVSKV
TSLLALQDCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTES
AAALVICFPSIASHPVYYPSFEQVGDTDALRGDREISLSLLGAGACSATVSWKLQLKEIL
ERRSYTELYEHEKDLVWKMRYDVRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELP
VLNALELLDFSFPDRYVGSFAINSLKKLTDGELFQYLLQLVQVLKYESYLDCELTKFLLD
RALANRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKAL
NDFVKVSSQKATKPQTKEMMHMCMKQETYLEALSHLQSPLNPNIILAEVWRHLQLPLPLP
CCTDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQL
NKSNMVATAAFNKDALLNWLKSKNPGEALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGY
CEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALAKTDEEALKHFRLKF
NEALRESWKTKVNWLAHNVSKDNR
>A0A6P6H040|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Puma concolor|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINICDLPRMARLCFAIYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKSRGGKKFLAVLKEILDRDPLSQLCENEMDL
IWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQ
YVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWH
LRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAMKLNRAK
GKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGE
DSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTS
ETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGI
GDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTE
KFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEA
LKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6I9P3V0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Notothenia coriiceps|TrEMBL
MPPGKYGMQEEWEKKGDQEIVMDFLLPTGIFLKFPVSPNDTIKTLKKMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEEWRRISDIRPFMCVLRLVAREGDRVEKLTNTQISWL
IGKGLHEFEAQKNHEVNEFRTKMRAFCEEKAQERQMLPWQQWMEYSFPCDLEPCVSPPEY
GSVKSKNTKKMFINVMFEASDESFMLQQDPQDPPVALMRSALKKKATVFRSVRQEPEDFT
LQVNGGWEFIYGKHPLCQFKYIFHCIRNGQNPLVTMVHHSTIRRYQNDQGLCSQIYRNRS
LSRPPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSEFLCKVVT
TMEVSVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKHKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKTDLFNPMGTVEKNPNVDSAAGLLIRFPNIR
PHPLYYPPLDKVGDMEKNGEAANATKEELMKLKVIMDNKNYMEFFEDEKDLLWKLRTEVR
DRYHESLSKLLLITKWNRRQDVVQMVSLLSNWRDLPAIHALELLDYNFPDPAVRSFTIRC
LRKLSDAELLQYLIQLVQVLKYESYLDCDLATFLLERALSNWRIGHFLFWHLRSEIHVAS
VSLRFGLILEAYCRGNIHHIKLLSKQIEALGKMKALSDFVKSGSQKMTADDLKLCIRQES
YMEALSDLLSPLNPSVILADICADRCRFMDSKMKPIWLMYNPKVQEDMVGIIFKSGDDLR
QDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSA
ATAAFNKDALLNWLKSKNPEDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYK
ILCRNGSLFVNLLAMMKAAGLPELTSFKYIQYLKVCNNNDMIISKSEEEALKNFKVKFNE
ALQESWKTKVNWMMHSLAKDNRP
>A0A091H4J3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Buceros rhinoceros silvestris|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSSELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYFTDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEQHLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLR
>A0A3B4GBR2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pundamilia nyererei|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDSEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNVRLDECRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A3Q1FKR0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acanthochromis polyacanthus|TrEMBL
MDGQQIQVSDEEPEVLREESRRRRRRKKAITSSSCTSMDQISVEFVLPTAARGGNGPDSL
LLEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQQFSPDHCILLYQKKGNVCEIYDKHQVFQ
TLDCIRYWRALKKDVGRIQLVPRPHPSEESQQYQSYLNCLIGYDVTDVSNVHDDELEFTR
RKLLTPRRIELSDRDPKLYSMDPWVTRKPLHEHLRTKINNSHILVVIHISTASQTIKVSI
DDTPTQVLASFFAKTANKRVLLGIPENKCETDFVLRVCGREEYLYGEKPLQNFNWIRQCL
KNGEEIHLVLETPPDPELDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDC
NRKFRVKVLGIDIPSLPKVPDFVVFIEASIFHGQQLLAQERTTSKSFSEEVLWNCWLEFN
IKIKDLPKGARLSLQVICGKQPQTPNSKGGYYQDNTAGTSTLDGKTKSRLLYYVNLLLID
HRSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVL
PKSRDVGRDYGAAGEEVEGGERGQREMPNHLKKQFEAIVATDPLHPLSPEDKELLWHFRH
ECMRNPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQV
RSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLR
SEIAQSMHYQQRYAVLLEAYLRGCGENMLQDFRKQVEMTEALQKVTCEIKAMSDDKYHVT
AQVVFQLRQKLETLQASGLPESFRVPYDPGLRAGVLLIEQCKVMASKKKPLWLQFKRADP
TTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIE
IVKDATTIANIQQSVVGSTGAFKDELLCQWLRDKCVNEEKFQQAVERFLFSCGGYCVATY
VLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGK
KSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRS
EDDARHHLLDQIEICREKGWMVQVNWFVHLVLGIKQGVEKRST
>A0A8C6K2G4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Melopsittacus undulatus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GPFHIPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKTA
AKPPPLPKKKPNYGSLWSLEQSFYIQLVQGSKVNADEGMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWQQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQVRNMFFGGHRNSPMISLLQTWPELPVLNALELLDFSFPDRYVGSFAVNSL
KKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAV
ALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMMHVCMK
QETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNG
DDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMQSDTIANIQLNK
SNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCE
KAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKVREAELRYS
>A0A3B3WK14|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia mexicana|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRNSSGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKISHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLTRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEASSKSLWSINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLPYDMYIPDVPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMNAVEDHANWIISRELGFNFNLSVNHSGTQQSSRAARDHALTESDGEQMRQL
SNRDPLSEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDDVAQMYCLLKEWPSIR
PEQAMELLDCNYPDPVVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDSPLARFLL
KKALTNQKIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLIN
LTDILKQEKKDETQKVQMKFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLEECRIMSS
AKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRML
PYGCLSLGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGETYDLAV
DLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPF
VLTQDFLIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQ
SFDDIAYIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A3B3YL17|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia mexicana|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFIEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIMSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLENFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCENVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVSLFDYMDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
RFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAADAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCLNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDRVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNHGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLMLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>G1SMR9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryctolagus cuniculus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQLLW
KQVHNYPMFNLLMEIDAYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEEKIQSLVGLSWIDWLKQTYPPEH
DPSSLENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
ASPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRITSHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASNDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A811ZQC9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nyctereutes procyonoides|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C7ZXX7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias sinensis|TrEMBL
MHPGIYGMLEEWEDGDQEINMDFLLPTGIFLKFPVSRNDTIKHIKEMVWRNARSEALFSG
LGDPDGYVFTCINQTAEREELEEEFRRIRDVKPFMCVLRLVAREGNRQEKLTNTQITQLI
GKGLHEFESQKNHEVNEFRTKMRTFCEEKALERQYLPWQRWLEYSFPCDLEPCRTPSGFG
SVKLKSSKIFINVKFEASDESFMLQQDCQDLPVALMKSALKKKATVFRSLRQEPEDYILQ
VNGRWDFIYGKHPLCQFKSRSLSRPPPLPLKRQNTSSLWSINEPFYIQLLQGSRVNADEG
MKLVVQAGLFHGSELLCKVVTSLDVTVCSEPLWDQRLEFDINVCDLPRMSRLCFALYAVI
EKTKKPKSTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSMWPSVPDDKSDLLNPMGT
VEKNPNVDSAAGLLIRFPNIRPHPLYYPSLEKHLKLKEIMDNKHYTEFFEDEKDLLWKLR
TEIREHYPENLSKLLLVTKWNKREDVVQNSWHALPLKWPDLPAIHALELLDYSFPDPAVR
SFTVRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRS
EIHVASVSLRFGLILEAYCRGNIHHIKILNKQNEALAKMRALSDFVKSGSQKMTVEDLKL
CIRQETYMEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNPSTPGDMVGIIF
KNGDDLRQDMLTLQMIQLMENMWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQ
LNSSNSAATAAFNKDALLNWLKSKNPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDN
IMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRE
YCEQAYKILCRNGMLFVNLFAMMKAAGLPELTCFKDIQYLKDSLALGKSEDEALKNFKVK
FNEALRESWKTKVNWMMHSLAKDNRA
>A0A7K9V888|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anseranas semipalmata|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNSSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTADFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQKQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHTVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A665UKL2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MDGQQIQLSDDEPKFQREEIRRRRRKKAITSSSGTSMDQITVEFILPTVARGGNSPDSLQ
LEVAGNWTVEQVKAQLWLKAVTSNLCPDFYQRFSPDHCILLYQKKGNLYEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESLHYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVSNGHILVVIHIATASQTIKVSID
DTPAQVLASFFTKTANKRVLLGIPENMCETDYVLRVCGREEYLYGDKPLQNFNWIRQCLK
NGEEIHLVLETPPDPNQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTVSMWDCN
RKFRVKVLGIDIPSLPKVPEFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNSWLEFNI
KIKDLPKGARLNLQVVCGKQPQTPNSKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEK
SEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVSRDVPREMPNHLKK
QFAAIVATDPLHPLSPEDKELLWHFRQECMRDPRAYPKLLSSVRWGKQEDVLTTHHLLER
SSAWDSSGLDVGLAMQMLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYH
DSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEAMLQDYK
KQVEMTEALQKVTREMKTMSADKYDVTAQVVFQLRQKLETLQLSGLPESFRVPYDPGLRA
GGLMIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQDMLILQILLIMES
IWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFKDEILYQWLRD
KCISEDKFQQAVERFLFSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYK
SFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTNLLIILFSM
MLMTGMPQLTSKEDIEYIREALTVGRVEDEAQRHLLDQIEICREKGWMVQINWFVHLVLG
IKQGVEKRST
>A0A665VXR2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TLPLFPALGEMESYMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRLSEERMQRVQKMSFSEWLQACFSPQLEPA
GTTITDGVNEQFSLLVFQDSASLKVSSSCTPTELMEQAVRKWLTTHGPEEEAWRGQYVLR
LSHCLEFLFGDHPLIQYKYIRTCMQAKESPHLTLVHNSTVKAMFDKEMSTIGAVVNRKSS
NPPLPLPPKRRHPTTCVWDVSRPFKIVLVNASKVNAEETAKVQVRAGLFHGTELLCKPAV
SSESSGRSDHMWKENTLEFDISVSDLPRMTRLCFAIYAVMDKVKKQKSTKNPHINKYQTI
RKAGKVHYPIAWVNTMVFDYKGQLKTGDINLHCWSSFPDELEEMLNPIGTIQTNPYTENA
TALYIHFPEYSSHPVVFPPFDKILEKAAEIARASDCGTMGRGGKKFHIELKEIMERDPLS
QLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALE
LLDFNYPDQYVREYAVRCLRDMSNEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGNR
KIGHFLFWHLRSEIHMPAVSIQFALILESYCRSCIPHIEILKKQVEALSKLKSVNELIKL
GTTKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPHILLSGIKCRYMDSKMKP
LWIVYNNKLMTGDNLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATG
DRAGLIEVVSSADTIANIQLTSKDGREFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQL
FHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLIL
RKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESW
TTKVNWMAHNVAKDNRS
>A0A7L2FBR0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Quiscalus mexicanus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPTKNIFVNIRFQSGGESFMFQISPWEFPITLMSYAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFDIR
DQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREAFSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A093CJJ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tauraco erythrolophus|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGTDGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLLEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGREDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRTITSVWDISNPFKIILLKGNKLNTEETAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHVRFQDYSKQPINYPPFDKILEKAAEIARSSDNAAMTGRGGKKFYVVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
PPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNSYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQMLRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A674PRR9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
MPPGKYGMQEEWEKEGDQRIVMDFLLPTGIFLKFPVSRNDTIRTIKKMVWKNAQSEALYA
ALGDPDSYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVARVGDRVEKLTNTQISQL
TGKGLHEFEAQKNHEVDEFRAKMRTFCEEKAQERQVLPWLQWMECNFPCELEPCSSPVEC
GGVKSKNTKIFINVKFEASDESFMLQQDPQDLPAALMRAALKKKATVFRSVRQEPEDYTL
QVNGRWEYIYGRHPLSQFKVSCLSLTELLSFSLPVTSLSSSQTLNFEHSLHHCVDNLHPP
LLYQNTSSLWSINEPFHIRLLHGSRVNAAEGMKLVVQAGLFHGSELLCKMVTSTEVAVCS
EPVWDQKLEFDINFSDLPRMSRLCFALYAVIEKNKKPRGTKKKNKKADCPIAWVNTMVFD
YKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIQFPNVRPHPLYYPP
LEKISDLEKNGNSPVCSCLPMSLCSLQHIKLKEIMDNKNYTEIFEDEKELLWKLRSVVCD
HYPESLSKLLLITKWNKREDVVQMVGLLRYWSDLPAIHALELLDYSFPDPAVRAFTIRCL
RKLSDEELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNSRIGHFLFWHLKSEIHVPSV
SLRFSLILEAYCRGNIWHIKLLIKQNEALLKMKTLSDIVKSGSQKMTVDDLKLCIKQESY
LETLSDLLSPLNPSVVLAEICADKCRFMDSKMKPLWLMYKSPWAQGDMMGIIFKNGDDLR
QDMLTLQMIRLMEILWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSA
ATAAFNKDALLNWLKSKNPEGKLEKAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYK
ILCRNGMLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDNRP
>A0A8D0HBE7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphenodon punctatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYSKLDKGHIIVVIWVIVSPNNDKQKYTLKINHDCVPENVIAEAIRKKTRSMLLSTEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWAINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PFAWGNINMFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMTVIEEHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNGLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHWLKDKNKGEMYDAAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAY
IRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7L0BM91|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Spizaetus tyrannus|TrEMBL
MPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAL
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C5CC51|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MDPHTICAASGEEDCGALSRTRRRRKGITSASLSAMDQITIEFILPTTPKNGLSPHTTLL
EVPGNWTVEQVKAQVWLRAVASNFSPDFYHKFSPDHCILLYMKKGTLCEIYDKHQVFQTL
DCIRYWRALKKDVGRISLVFRPPQQDEALRYQRFLNQLIGYDVTDVSNVHDDELEFTRRK
LLTPRRNELQERDPRLYAVDPWLTDRPLRDHLLSKVMNGHLLVVIHIFTTSQTIKVSIDS
TPEQVLASVFAKTANKRALVGIPDDVCESDFVLRVCGRYEYLYGDRPLQDFSWIRRCLKN
GEEIHLVLEKLPDTDLDQVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNR
KFRVKVLGIDIPLLPRNPDLTVYIEASIFHGQQLLAQERTTSKPFMEEVLWNTWLEFDIK
IRDLPKGARLNLQVGSKVTHKTRLQYYVNLLLVDHRSLLRQGEFVLHMWKIPEKGEESSS
SVNADKLTSATNPDKASSMAVAVSLDKYCYPVVLPKKDSGEPGGERGQREMPNHLRKQFE
AILAKDPLHPLSPEDKELLWHFRHECMRHPRAYPKLLASVRWGRQEDVQAAHAMLERSSA
WDSSGLDVGLALQMLDCNYSDAQVRSMAVRKLETLGGDDVLRYLLQLVQAVKFEPYHDSA
LVRFLLKRALRSKRIGHFLFWFLRSEIVQSLHYQQRYAVLLEAYLRGCGDAMLTDFHKQV
EVTEALQKVTREMKAMLADKYDVSSQVVFQLRQTLEALQSSGLPQTFRVPYDPGLRAGTL
MIEQCKVMASKKRPLWLQFKRADPSSLSSDPIGIIFKDGDDLRQDMLILQILLIMESIWE
TESLDLYLLPYGCISTGNRIGMIEIVKDAATIANIQQSVVGSRGAFKDEILNQWLRDKCV
NEDRFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFM
GISKEWVPFVLTPDFLYVMGTAGKKSSPHFQKFQDVCVKAYLALRHHTNQLIILFSMMLM
TGMPQLTSKEDIDYIREALTVGRSEEEAERHLLEQIEICREKGWMVQINWFVHLVLGIKQ
GVEKRST
>H0ZKH3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C5CHJ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MPPAMTDILDMWSPLAGHATELVPVDFLLPTGIYIQLEVPSEATIQHIKLLLWKQAQTYP
LFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLRLVTRNCGRAERLLDSKI
GVLIGKGLHELDALQAQEVKDFRAKMLRVSEARMQFYHAMTWSEWLQACFSPQMETTGAA
PPAASSYSQEDYLKITIHFDQSQDAASLRVSPAFTPTEVMEQGLKKWLTTHGPEDDSRQG
PYVLRVSQRLEFLCGDHPLIQYKYIKECIQAREPPHLTLVLTSTIRTMFEKEISAIGAVV
SRKSSNPPVPLPPKRRASTVSTSARIHLPLVTPPAPQVQVRAGLFHGTELLCKPAVSSES
SGRSEHAWSDGTLEFDIVASDLPRMTRLCFAVYAIMDKVKKQKSTKNTHSNKYQTIRKAG
KVHYPIAWVNTMVFDYKGQLKTGDVILHSWSSFPDELEEMLNPIGTIQTNPYTENATELH
VHFQEYSSQPIVFPPFDKILEKAAEIAKANDLVPMGRGGKKFHIELKEIMERDPLSQLCE
NEKDLIWTLRHDCHLKFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPRLSPRDALELLDF
NYPDQYVREYAVRCLREMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLERAQANRKIGH
FLFWHLRSEIHMPAVSIQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIK
TARSKTKEAMLTKEAMMTCLRQSGYSETLSDLNSPLNPSIQLSGINVERCRYMDSKMKPL
WIVYHNKLLRGDSLGIIFKNGDDLRQDMLTLQILRLMDLLWKENSLDLRIVPYGCLATGD
RAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALDRAIEEFTLSCA
GYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIH
VIQQGKTGNTEKFGSFRQYCEDAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C1FTK5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRLVVQAGLFHGSELLCKVVISNEVSVCSEPVWDQKLVFDISVSDLPRMSR
LCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFSMSTWPSVPDDKG
DLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKVNFVVLLNVSHETERDCGHK
NYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVSLLRKWPELPAIH
ALELLDYSFPDPHARSFTIRCLRKLSDDELFQYLLQLVQVLKYESYLDCDLTCFLLERAL
ANKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSIFHIKSLIKGTALCCLKKALNDF
VKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKP
LWLMYKNKYDNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRDKLDQAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMISETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDF
VHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYL
KDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A8C1G1Y8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVI
SNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNDLGMNGEKTTKEEVRNNMHRSRDCGHKNYTEFFEDEKELLWKLREEVR
QRYPESLPKLLLITKWNKHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIRC
LRKLSDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPS
VSLRFGLILEAYCRGSIFHIKSLIKGTALCCLKKALNDFVKSGSQKATRIQTTEDMKVCI
KQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDD
LRQDMLTLQMIQLMDYTLLSNAALRMPVNWNKTGLIEVVKNSDTIANIQRNNSNSAATAA
FNKDEFTLSCAGYCVATYVLGIGDRHSDNIMISETGQLFHIDFGHFLGNFKSKFGINRER
VPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMKAAGLPEL
SSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A8C1FTJ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVI
SNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKVNFVVLLNVSHETERDCGHKNYTEFFEDEKELLWKLREEVRQRYPESLPK
LLLITKWNKHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLSDDEL
FQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSLRFGLIL
EAYCRGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEAL
SDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQDMLTLQ
MIQLMDVLWKTEGLDLRICRTWSTFSEEQCSVQLFRTNKELMNNYHKTERQSWIIQVTTH
SIKNQGFPNF
>A0A8C2ALU1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MEHQASDDEPPVVRREENKRRRRKMKAFTSTSAVSTDNIAVDFVLPTTNKNSRNPDTLHI
DVTGNWTVEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVVRTQPNEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELADRDPKLYSMDPWITPKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFAKIKKKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKN
GEEIHLVLEHPPDPELDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFHIK
IKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLLVDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERG
QREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEA
VMITHHLLERCTVWDRSSLDVGLAIQLLDCHFSDEKVRTMAVRKLETLEDDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALRSQRIGHFLFWFLRSEIAQSMHYQQRYAGVVEAYLRG
CGEAMLQDFRKQVEMTEALQKVTREIKLMSAEKYDVSQQVVLQLRQKLEGLQTSGLPDSF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFMGISKERVPFVLTPDFLYVMSTTGKKSSPHFLQFQNVCLKAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLEQIEICRDKGWTVQ
FNWFLHLVLGIKQGVEKRSA
>A0A8C1RWL1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWVESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQNIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKRISEEKMQCMQLMSWGEWLRSCYSMTLEAGSLE
NLIDKHEGVIKITMHYDQSQDTSSLKVSLHCTVTELMDLALKKWQTTHVPEEDIGFRSDY
VLRVSRKLEFLFEDHHLNQCKYIRDCLLTNESPHLTLVHCDVVKAMFEKEISTIGSVLAW
KTSNPPLPLPPKKRLPTLHTCVWKVHSLFRIHLVKGNKVNAEDAAKIQVRAGLFHGTELL
CKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNK
YQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPY
TENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMER
DPLSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPR
DALELLDFNYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERA
QSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNE
LIKFGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGVNVERCKYMDSK
MKPLWIVYNNKLLGGDTVDIIFKNGDDLRQDMLTLQILRLMDLLWKEANLEYRDALDKAI
EEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPF
ILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSV
KDIQYLKVNRHEKENCNLLFLRLCDPI
>A0A8C1NGI2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSLQ
INGRWEFIYGKYPLCQFKLISFFPLLQYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLS
NQVSRSRAQSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGS
ELLCKVVISNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNK
RADCPLAWVNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLL
IRFPNIRPHPLYYPPIEKLNDLGMNGEKTTKEEHMKLREIVDNKNYTEFFEDEKELLWKL
REEVRQRYPESLPKLLLITKWNKHEDVAQTLKNVTLLLAHQMRFFLNSDDELFQYLLQLV
QVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSI
FHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLN
PSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQDMLTLQMIQLMDVL
WKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLK
SKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMISETGQLFHIDFGHFLGNFK
SKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFAL
MKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFAK
DNR
>A0A8C2AYL9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MEHQASDDEPPVVRREENKRRRRKMKAFTSTSAVSTDHIAVEFVLPTTNKNSKYPDTLHL
DVTGNWTVEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVIRQQPNEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELADRDPKLYSMDPWITPKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAISDFHWIRQCLKN
GEEIHLVLEHPPDPELDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKENECKNKTRLLYYVNLLMVDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERG
QREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEA
VAITHCLLERSTVWDRSSHDVGLALQLLDCHFSDENVRTLAVRKLETLEDDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRG
CGEAMLQDLRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDSF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSRDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLSEKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFMGISKERVPFVLTPDFLYVMCTTGKKSSPYFLQFQNVCLKAYLALRHH
TNLLIILFSMMLMTGMPQLSSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQ
FNWFLHLVLGIKQGVEKRSA
>A0A8C2GQC6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRLVVQAGLFHGSELLCKVVTSNEVSVCSEPVWDQKLVFDIGVSDLPRMSR
LCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFSMSTWPSVPDDKG
DLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKLWLAEHMKLREIVDNKNYTE
FFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVSLLRKWPELPAIHALEL
LDYSFPDPHARSFTIRCLRKLSDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKK
IGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSIFHIKSLIKQNEALNKMKALNDFVKSG
SQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLM
YKNKYDNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIE
VVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVAT
YVLGIGDRHSDNIMISETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGR
TNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGK
SEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A8C2HSQ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWVESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQNIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKRISEEKMQCMQLMSWGEWLRSCYSMTLEAGSLE
NLIDKHEGVIKITMHYDQSQDTSSLKVSLHCTVTELMDLALKKWQTTHVPEEDIGFRSDY
VLRVSRKLEFLFEDHHLNQCKYIRDCLLTNESPHLTLVHCDVVKAMFEKEISTIGSVLAW
KTSNPPLPLPPKKRLPTQLHTCVWKVHSLFRIHLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSP
RDALELLDFNYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLER
AQSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVN
ELIKFGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGVNVERCKYMDS
KMKPLWIVYNNKLLGGDTVDIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGC
LATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
HDFIHVIQQGKTSNTEKFGKTLWHWVKLMRRPSNSSGRSLMKLCERVGPPKSTGWPTLWL
TLHKPRETQHQAPN
>A0A8B7KB41|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Camelus ferus|TrEMBL
MLPKFGPISFQVAQGMELENYEPPVVLREDNCRRRRRMKQRSTAASLSSMELIPIEFVLP
TSQRNTKTPETALLHVASHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQ
WYEIYDKYQVVQTLDCLRYWKVLHRSPGQIHLVQRSTPSEETLAFQRQLNALIGYDVTDV
SNVHDDELEFTRRRLVTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIH
RSTTSQTIKVSADDTPGTILHSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGET
PIKNFQWVRQCLKNGEEIHLVLDTPPNPDLDQVRKEEWPLVDDCTGVTGYHEQLTIHGKD
HESVFTVSLWDCDRKFRVKIRGIDIPILPRNADLTVYVEANIQYGQQVLCQRRTSPKPFT
EEVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSGKASAETPSPESKGKAQLLYYVN
LLLIDHRFLLRHGEYVLHMWQLSGKGEDHGSFNADKLTSATNPDKENSMSISILLDNYCH
PIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKD
PKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAV
QKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQ
SRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIS
QLKQKLENLQNLNLPQSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSN
ETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDA
TTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIDEKFQAAVERFVYSCAGYCVATFVLGIG
DRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLH
FQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIDYIRDALTVGKSEEDAK
KYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A7K8RNV9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhodinocichla rosea|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAIETSHTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFRKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A485NZX9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lynx pardinus|TrEMBL
MELDNYEQPVVLREDNRRRRRRMKPRSTTASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVATDFYRRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSDETLAFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXRRRLVTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIF
IVIHRSTTSQTIKVSADDTPGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYL
VGETPIKNFQWVRQCLKNGEEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTI
HGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSP
KPFTEEVLWNVWLEFSIKIKDLPRGALLNLQIYCSKVPVLAGKTSAETPSSESKGKTQLL
YYVNLLLIDHRFLLRHGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLD
NYCHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYE
SLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVR
AIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRS
EIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTDQVQVIEMLQKVTLDIKSLSAEKYDVSS
QVISQLKQKLENLQNSNLPKSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPT
ALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEI
VKEATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFV
LGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKK
TSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSE
EDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A087RJ01|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aptenodytes forsteri|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
TGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K9ZT25|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicrurus megarhynchus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAGWMEYNFPLQLEPMAKGPGP
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKLSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A668VNB5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKSKNIKKIFINVKFEASDVSSSVVDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQV
NGRWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTITKYQEEQGRMCSQVYKMLKSS
ASKPHVLPPSNHYCVSVVPLQLVVQAGLFHGSELLCKVVTSSEVTVSSEPLWNQKLEFDI
NVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKAPDGRKDCPIAWVNTMVFDYKDQLKT
GEFHLSTWPDLLNPMGTVEKNPNVDSAAELLIHFPNIRPHPLYYPPLEKVPSPKRLHKTY
FKLKEIMDNKNYTEFFEDEKELLWKLRTEVRDHYPESLSKLLLITKWNKREDVVQMVNLL
RNWPDLPAIHALELLDYSFPDPAVRSFTIRCLRKLSDDELLHYLIQLVQVLKYESYLDCD
LTTFLLERALSNRRIGHFLFWHLRSETHVASVGLRFGLILEAYCRGNIHHIKLLTKQNEA
LGKMKALSDFVKLGSQKVTAEDLKQCIRQESYLEALSDLLSPLNPSIILSEICTDRCRFM
DSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPY
GCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDQAIE
EFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFI
LTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFK
DIQYLKDSLALGKTEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A668VNB8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKSKNIKKIFINVKFEASDQDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQVNGRWD
FIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTITKYQEEQGRMCSQVYKMLKSSASKPH
VLPPSNHYCVSVVPLQLVVQAGLFHGSELLCKVVTSSEVTVSSEPLWNQKLEFDINVADL
PRMSRLCFALYGVIEKTKKPRGTKKKNKKAPDGRKDCPIAWVNTMVFDYKDQLKTGEFHL
STWPDLLNPMGTVEKNPNVDSAAELLIHFPNIRTHMWQILHSYNFCFLKEIMDNKNYTEF
FEDEKELLWKLRTEVRDHYPESLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELL
DYSFPDPAVRSFTIRCLRKLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRI
GHFLFWHLRSETHVASVGLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGS
QKVTAEDLKQCIRQESYLEALSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPA
VEGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVV
KNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYV
LGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTN
NSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTE
DEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A668VND3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKSKNIKKIFINVKFEASDESFMLQQDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTITKYQEEQGRMCSQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKVPSPKRLHKTMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLRKL
SDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASVGLR
FGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESYLEA
LSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLRQDM
LTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATA
AFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLF
HIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILC
RNGTLFVNLFAMMKAAGLPELTSFKDIQYLKVCHSNDVAVNDYEENNNNVNNLWFLVFKR
TL
>A0A668VZ66|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MEKKQQIQVSDEESQVPREESRRRRRKKAITSSCSNSMDQITVEFVLPTAARGGSGSDTL
QLDVAGNWTVEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQ
TLDCIRYWRALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRRIELSERDPKLYSMDPWVTCKPLPEHLLSKINNGHILVVIHIGTASQTIKVSI
DDTPTLVLVSFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCL
KNGEEIHLVLEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDC
NRKFRVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFN
IKIKDLPKGARLNLQVICGKQPQIPNSKGSSYQERKTKSRLLYYVNLLLIDHRSLLRQGE
FILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRD
WAVGGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHECMRVPRAY
PKLLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLE
TLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSKHY
QQRYAVLLEAYLRGCGENMLQDFRKQVDMTEALQKVTREIKTMSADKYDVTPQVVFQLRQ
KLENLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADSTTLSKDPIG
IIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIA
NIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHN
DNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKF
QDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLL
DQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>H3AZ97|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Latimeria chalumnae|TrEMBL
CLSSKMPPAVTDTLDIWAVDSQIAADGCITVDFLLPTGIYIQLDVPREATISKIKKLLWK
QAQSYPLFHALHEMDSYMFECVNQTAVQEELEDETQRLCDVRPFLPVLKLVTRNCDPAEK
LDSKIGVLIGKGLQEFDALEDPEVKDFRSKMRRIGEAKMQTLQSLSWVDWLKYTFPPELE
PTVPDNLQDKLYGGNLVVAIHFDTCQDVFSFQICPDINPVKLNELAIRKRLTIHGRENDE
INARDYVLQVSGRLQYVFGDYPLIQFQYIRNCVMARTLPQLTLVDCSNIKKIFEQEMNAI
GAAVSRKASNTPVPLPPKQRTLSQMSQSVCDINSPFKIVLVKGTKVNTDETMKVQVRAGL
FHGTELLCKPVVSSEISGKNDHLWNQTLEFDISVCDLPRMARLCFAVYAVMDKTKKPKST
KTINASKYQTIRKAGKVHYPIAWVNTMVFDFKGQLKTGDLVLYSWSSFPDELEEMLNPMG
TVQTNPYSENATALHIQFLSYSKMSIFYPPFDKILEKAAEIARSSDCMNMSGRGGKKFHI
ELKEIMERDPLSQLCENEMDLIWTLRYDCRENFPESLPKLLLSVKWNKHEDVAQLQALLQ
IWCKLSPRDALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPYLDCAL
SRFLLERAQANRRIGHFLFWHLRSEMHIPAICVQFGLILEAYCRGSIAHMKVLSKQVEAL
NKLKTINNLIKVNSPQSMKSARVKLKEAMHACLKQNAYLEALSHLQSPLNPSLILSEICI
SKCKVMDSKMKPLWIVYDNKMFGGDPVGVIFKNGDDLRQDMLTLQILRLMDILWKEAGLD
LRIVPYGCLATGDKSGLIQVVTAAETIADIQLDSSNVAAAAAFNKDALLNWLKEYNSGDE
LDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKSGQLFHIDFGHILGNFKSKFGIKR
ERVPFILTYDFIHVIQQGKTGNTEKFGRFRQYCEDAYLILRKNGNLFITLFALMLTAGLP
ELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHTMAKDYRS
>A0A7L0ZIZ6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oxyruncus cristatus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPVAKGFGT
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPVTLMSYAIKKQATVFRHETVQKAEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7J7E8U4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Diceros bicornis minor|TrEMBL
MELENYEQPVVLREVNRRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKMVHRSPGQIHVVQRCAPSEETLAFQHQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDQVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETSSSESKGKVQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALVRFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGMAMLHDFAQQVRVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPLEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITEMGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQQTEATLQFRK
TVSESNSLFRMILIDGVMPCKFQYSPVVLSLLSSGNNSNSISFSFIQDVCVKAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQ
FNWFLHLVLGIKQGEKHSA
>A0A852BL29|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chloropsis cyanopogon|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQRPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
CKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L2ZT24|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Prunella fulvescens|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHNFHWIRQCLKNGEEIHLVLDNPPDPNEDEVQKEEW
PLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRKFRVKIIGIDIPVLPRNTDLTVFV
EANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKIKDLPKGALLNLQIYCGKAQGPSA
KTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRSGEYVLHMWKIPGKGEEQGSINAD
KLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSDPQGDRTRAEMPNQLRKQLEEIIA
TDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQEIVAKTYQLLAKKEAWDQS
TLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARF
LLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLHDFMKQVQVIE
LLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGSKLPESFRVPYDPGLRAGALVIEK
CKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQV
>A0A851PT29|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anhinga anhinga|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAVPEDPDEKLQLKEILERRSYTELYEHEKDLVWKMRCD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEERGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRRVMMTPYGCLSTGDKTGLIEVVMHSDTIA
NIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFER
FRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHF
RLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L2KAJ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zosterops hypoxanthus|TrEMBL
MPPGIYCPTDFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWQQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPLTLMSYAIKKQATVFRHETVQKAEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKAP
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVAVCSEPVWRQRLDFDIGICDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2P4SFM2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bambusicola thoracicus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQ
>A0A1S2ZG88|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Erinaceus europaeus|TrEMBL
MCFNLMMPPAMADSLDIWAVDSHIAPDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWIDWLKQTYPPEH
ETSILENLEDKLYGGKLIVAVHFENRQDVFSFQVSPNMNPIKINELAIQKFLTIHGKEDE
VRPYDYVLQISGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNIPLPLPPKKTRVISHIWENSNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHLWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPDNKKQPYYYPPFDKIIEKAADIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFMFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLALQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRRDYRS
>A0A1S2ZEH0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Erinaceus europaeus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDIRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETATKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNKQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQSFVSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8J7NIV5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Atractosteus spatula|TrEMBL
MLISLISPLIICSCTFQIGLVMEQREDVKQPVVFRDESTRRRRKMKAFTSNSLVTMDQIT
IEFVLPTSKKFNKTPEAILVDVAGNCTVEQVKTQVWMKAVAANLCPEFYQKYSPDQCILL
YQKKGHWYEIYDKHQVFQTLDCIRYWKALKKDQGRIHLASRPQPTDESQQYQRYLNYLIG
YDVTDVSNVHDDELEFTRRKLLTPRMIELAERDPKLYSMDPWITSKPLPEYLLNKISNNH
ILVVIHRHTSSQTIKVSIDDKPLQILQSFFTKIAKKRSLLGIPEEVSEQDFVLRVCGREE
YIFGNHAIKDFHWVRECLKNTEEIHLVLESAPNPDQDVVHKEDWSLVDDCTGVAGSHEQL
TIDEKDHEKVFTISMWDCNRKFRVKVLGIDIPTLPRNSELIVFVEASIFHGQQLLAQERT
SSKPFTEEVLWNTWLEFNIKIKDLPKGARLSLQVFCGKAQTQTGKAGFQESVNYDSKCKN
RLLYYVNLLLIDHRSLLRQGDYILHMWKVPEKSEDHGSINADKLTSATNPDKDNSMAIAI
LLDKYCYPIALPKGQDSVEAEGERGRREMPNHLRKQFEEIVVTDPLHPLSPEDKELLWHF
KXAYPKFLSSVKWGKQEAVLATHQLLEKHDTWDRSPLDVGLAMQMLDCNFSDANVRTMAV
RKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQ
SMHYQQRYAVILEAYLRGCGEAMLQDFKKQVEITEALQKVTREIKTMSADKYDVSVQVVF
QLRQKLENLQSSGLPESFRVPYDPGLRAGALVVEQCKVMASKKKPLWLQFKRADPTTLSS
DTIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLSLLPYGCISTGNKIGMIEIVKDA
TTIANIQQSTVGNTGAFKDEILNQWLRERCLNEDKFQLAVERFVYSCAGYCVATYVLGIG
DRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTFGKKTSPH
FQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKTEDEAQ
KHFLDQIEICRDKGWTVQFNWFLHLVLGIKQGVEKRSA
>A0A8C5TT70|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Malurus cyaneus samueli|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SIQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQVFFFILLSCLLMTFTYICSVYYSMQNSVGSVTSLNCLI
FLWQVHVRAGLFHGTELLCKTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYA
VMDKMKTKKVQKKKPIKKSMCIKNAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLN
PMGTVQTNPYTENATALHIRFQEYSKQPINYPPFDKGRGGKKFYVVLKDIMERDPLSQLC
ENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPREALELLD
FNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIG
QMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAM
KQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKPLWIVYN
NKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATGDHSGLI
EAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLSCAGYCVA
TYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQG
KTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALG
KSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A093FQM0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tyto alba|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLVPELQSFDDIAYIR
KTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A4W4HIX2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MPPGVCYGMQDVWEKGGREQVTLEFLLPTGIYLSFPVARNDTIGTIKKMVWKNARSEPLF
SVLSDPDAYVFTCINLTAEREELEDESRRLCDVRPFMPVLRLVAREGDRVEKLINTQISL
LIGKGLHEFDTQKNHEVNEFRAKMRSFCEENAQDRQRLPWHQWMKCNFPCDLEPFSMVVQ
SGKSCSVKKLLVNVKFEASEVSHRMLCTHLVSHNTPLINEEIHNLDIVSQFFRPLKQEKP
ENYTLQVNGRWQFIYGNSPLCQFKVRGLASCLPRCTLGAFKFCLRFTEGQVGGRGWEVGV
GCVGRAGLFHGGELLCKVVTSSEVSVCSDPVWDQKLVFDINLCDLPRMSRLCFTLYGVLE
KTKKQRSTKKKNKKAVSLRGGSDCPLAWVNTMVFDYKDQLKTGEFLLSTWPSAPGDLLNP
MGTVERNPNIDSTAGLLIRFPSFRPHPLYYPPLEKVNRTASAINTPRPTNLNSHLKLKEI
VDNKNHTEFFEHEKELLWKLRLDVRAHYPESLSKLLLITKWNKHEDVAQMVCLLRTWRDL
PPLHALELLDYTFPDPHVRSFTIRCLKKLGDEELFQYLLQLVQVLKYESYLDCDLTTFLL
ERALSNKKIGHFLFWHLRSEMHVASVSLRFGLILEAYCRGSIYHIKSLMKQIEALNKMKA
LNDFVKSGSQKSASRLQITEDMKLCIKQDTYMEALSDVISPLSPSIVLSEIWYDRCKFMD
SKMKPLWLMYKNKWDHLDTVGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMVPYG
CLSTGNKTGLIEVVKNADTIANIQRNSSNNAATAAFNKDALLNWLKSKNPEDKLDQAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKAKFGINRERVPFIL
TYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMRAAGLPELSCSKD
IQYLKDSLALGRSEEEALKNFKVKFNEALRESWKTKVNWMMHTVAKDNR
>A0A452FAR7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Capra hircus|TrEMBL
MCFYFMMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISCIKQMLW
KQVTNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPEL
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHSLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMVAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEPLEFDINTCDLPRMTRLCFAVYAVLDKVKTKKSTKTM
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPHALPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A2K6AN06|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca nemestrina|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFVLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A060VNB5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MPPRPSSGELWGMHLMPPSIMVDCLLPNGMILTLECTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDAEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVSIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A3Q7X9W8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus arctos horribilis|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRHSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLLDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIQI
KDLPRGALLNLQIYCSKAPAPTGKGSADTPGSEGKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLEAY
LRGCGTAMLHDFSQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8D1VNF0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPGVDCPMEFWTKEENQSVDVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKVSQRLALPLPSSPSSPCRRPTREPIGQHSGPGAGPGPLTQAPWLVHVKSR
AFEHPWPTGPVCGGGALRPPLSSQDLLPARLAEFHSLGSSEVSGPSGTCAAGLPVTAGVV
GSTELYRKPAKPPPTPPAMTTGLVTGASLLRIPLLQWPCFSVHLHTQPSSVSLWSLEQPF
CIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSVCSDPVWKQRLEFDINVCD
LPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWP
SVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAPHPVYYPSLDKILELGRHGEHGRF
TEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNRHEDVAQ
MLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYES
YLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLM
KQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDPSILLAE
VCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQ
EGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKN
PGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKF
GINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYAILRRHGLLFLHLFALMRA
AGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNR
Q
>A0A8D1M1S0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MCFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDYPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSLQALLQIWPKLPP
REALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLER
ALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLKTLN
SLIKLNAMKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKM
KPLWLVYNNKVFGEDSIGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLA
TGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTL
SCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYD
FIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>L8HUM8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus|TrEMBL
MCFYFMMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISCIKQMLW
KQVTNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPEL
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHSLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMVAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEPLEFDINTCDLPRMTRLCFAVYAVLDKVKTKKSTKTM
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPHALPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKTEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A1L256|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Danio rerio|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYAYPPNVESSPDLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKIAHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGLQHTPEGAAAVRNIRQRQHQRHRQDLRQDRNISRRRTAV
>A0A6I9IMT9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vicugna pacos|TrEMBL
MCFHSIMPPAMADILDIWAVDSQIGSDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRSTIHGKEDE
VSPHDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFHIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIVLHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASNDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVMLSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6P8GPI8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Clupea harengus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVCLECLREAPLLTIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFQPLLKVIEPIGNREEKILNREIGFA
IGMPICEFELVKDSEVQDFRRSILCVCREAMEEREGGGAHSQALYVYPPNVESSPDLPPH
IFSKLDKGRLIVTIWVIVSPSNAKQKYTLKISHDSLPEQLIAEAIRKKTRSMHLSAQQLR
MCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVSRLPHLMLVSKDSLYSQLPAS
GFVAPSYSRRTPQPSPCPGGSDPSPPRTLWAFNTLLRLRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVHTQRVPCSNPRWNEWLTYDIYLTDLPRAARLCLSICSVKGRKGAKEE
HCPLAWGNVNMFDYKDTLVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVMFPDEQQIEEHANWVISRELGYNYCMGLSSRLACDSTVSPSDGEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLQAVKWNSRDEVSQMYCLLKDWPLMQPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKVKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKR
PLWLNWENPDIMSELLFTNNEVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYG
CLSIGDCVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDKAIELF
TRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLT
QDFLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFD
DIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A8C9JDR7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera tigris altaica|TrEMBL
MELDNYEQPVVLREDNRRRRRRMKPRSTTASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVATDFYRRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQLPVGQRHAPSAETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCRGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCSKAPVLAGKTSAETPSSESKGKTQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTDQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKEATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>H9FVU5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca mulatta|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8B7EE59|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcebus murinus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRAGRRKDSI
REMVKGAQVSEMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWL
KDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHK
KKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINL
FSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHT
IKQHALN
>A0A6P7RK75|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus caroli|TrEMBL
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLD
CLHYWKLMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIANNCIFIVIHRGTTTQTIKVSADDT
PGTILQSFFTKMAKKKSLMNIPESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
DEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFGIKI
KDLPKGALLNLEIYCCKTPSLSSKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRHGDY
VLHMWQISGKAEEQGSFNADKLTSATNPDKDNSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSNLP
ESFRVPYDPGLKAGTLVIERCKVMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGSSGKKTSPHFQKFQDVCVRAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8C3I1V2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysemys picta bellii|TrEMBL
MPPAMTDILDIWAVDSQIGADGLISVDFLLPTGTYINLDVPRDATICHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVCEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVKEFRSKMRRISEEKLLSLVGLSWVDWLKHSYPPEQEPSVPE
NFQDKLYGGNLVVAIHFDKCQDVFSFQVSPNINPVKLNELAIRKRLTIHGKDNEVDPSDY
VLQISGRLEYIFGDHPLIQFQYIRKCVMNRTLPHLTLVECCSIKKMCEQEMIAIEAAINR
KSSNLPLPLPPKKTRTVTQLTQSVWDISNPFKIMLLKGNKLNTEETAKVHVRAGLFHGTE
LLCKPIVSPEISGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKTINP
SKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDLLLHSWTSFPDELEEMLNPMGTVRTN
PYTENATALHIKFQEYSKLPIYYPPFDKILEKAAEIAKSSENAGMAGRGGKKFYIELKEI
MERDPLTQLCENEMDLIWTLRYDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWSKL
PPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLV
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGVILEAYCRGSIAHMKVLSKQVEALNKLKT
LNSIIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELYVEKCKYMDS
KMKPLWIVYNNKMFGGDLLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGC
LATGDHSGLIEAVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKTEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>E0VFY9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pediculus humanus subsp. corporis|TrEMBL
MVHIPSPYAFDYWLREPTSSQVELSCLMPNGIFIPLPANRNAILLEIKEELWEEASKYPF
PGILRDASSYIFSCISTMGETEELRDENRRLCDIRPFCSVLKVIEKKKGDGDGDEKALNF
QISSLIGKGLHEFEALKNPEVNDFRWKMKLLGSEVARSRQNKSWLEKIAYQFPPRLASSS
AIPASCLARMREGSYFVIVSKFQNTDSAFKFNISYSTTPIQLLQLILNKKSITLNTKGEH
PSEFMLKVCGQEEYLIGGYPLVRFLYIQECLSREVTPTVVVIIMIKLNFLVDQDNVYENL
DDLDLSASRQTFSTLTLRKNKGKYLSSWTIDDRFSLKICAISRLNTDVNRTVGIQVGIFH
GGKPLCESQKTSEKAVLKDGKVDFEEELTFDIQISNIPRMARLCFAVYEISKSAKGVKAK
KVKDSKQDLYMNPLTWVNTTVYDFKNQLKTGDITLYMWTYAEDSQHEEMLQSLGTVVSNT
NVDHATALTLSFKSYSTEHTIIYPSVEKMIEHAEKYFDPCSVANFSPQDVKTYLENVRQL
AESDPLRDMHEQDLKELWALRYEAQKYVPTLLAKLLDTVEWNNRNEVAEAISLLQKWPRL
PVEKALELLDYAYADQQVRSFAVKCLQSVSDEELSLYLLQLVQALKHESYLSCDLVEFLL
RRALNNRKIGHFLFWHLKSEMTVPCVSIRFGLILEAYCRGSQKHMDILSKQLDYLNKMKE
TSELLRQRKDRDKARQWLHERLGESHCLEALSDVVNPLNPRFKMKKIKVEKCRVMDSKMR
PLYLVMENDDPYGDDVYIIFKNGDDLRQDMLALQMIKIMDMLWKNEGLDLRMNPYGCVST
EHRVGLIEVVLNAETIANIQKEKGMFSATSAFSKGSLLAWLKDYNPEENQLLKAIEEFTL
SCAGYCVATYVLGVADRHSDNIMVKKSGQLFHVDFGHILGHFKEKFGFRRERVPFVLTHD
FVHVINKGQKDKKEALEFQIFQNHCEKAFLILRRHGSLILSLFAMMISTGLPELSSEKDL
NYLRETLVLDLSENEALLHFRSKFCEALANSWKTSLNWASHNLAKNNKQ
>A0A2I4BU19|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Austrofundulus limnaeus|TrEMBL
MPPGKYGMQEEWEKEGDQEIDMDFLLPTGIFLKFPVSRNETIRNIKKMVWKNARSEALYS
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKITNTQISLL
IGKGLHEFEAQKNHEVDEFRSKMRTFCEEMSQERQSLPWQRWMEYSFPCDLEPCCSPPVH
GGTKAKNAKKLFVNVKFEACDESFMLQQDPQDLPVALMKSALKKRATVFRSMXQEPEDYT
LQVHGRLEFLYGNHPLSQFKYVFSCLRNGQNPQLIMVHHSTISKYQEEQGRVCSQACKTR
SLSRPPPLPMKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSEPLCKVV
TSSEVTVCSEPLWDQKLEFDINVSDLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPPLDKLIDMERNGETVSATKEEHMKLKEIMDNKNYTEFFEDEKELLWKLRTVV
RDFYPESLSKLLLITKWNKREDAVQMVSLLKHWPDLPAIHALELLDYSFPDPAVRSFTIR
CLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVA
SVSLRFGLILEAYCRGNIYHIKLLTRQNDALGKMKALSDIVKSGSQKMMVDDLKLCIRQE
SYKEALSNMLSPLNPSIILAKICADKCRFMDSKMKPLWLIYNNPTEQGDMVGIIFKNGDD
LRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNNSN
SAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERA
YKILCRNGMLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEDEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>V8NKC4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ophiophagus hannah|TrEMBL
MPPAMADILDIWAVDSHIAADSSISVDCLLPTGIYISLDVPRDATICYIKQLLWKEAHSY
PLFHLLLEIDSYMFSCVNQTAVREELEDETRRLCDIRPFLPVLQLITRSCDPGEKLDSKI
GVLIGKGLHEFDALQDPEIKEFRIKMRQISEEKMQSLMGLSLMNWLKHTYPPELEPAIQD
NFQDKLYGGNIVVAIHYENCQDVFSFQVSPNINPIKLNELAIRKWLTIHGKEHEEVDPYD
YVLQVNGRLEYIFGDHPLIQFQYIHCCVINRALPQLTLIECSTIKTMYEQEMIAIEVAIN
RKSNNLPLPLPPKKSRLTQSVWEIVQPFKILLVNGSKLNTEETAKVHIRSGLFHGNELLC
KPIVSSEIAGRNDHVWNEPLEFDINVCDLPRMARLCFVVYAVMDKMKNKKSAKALNPSKY
QTMRKAGKVHYPVAWVNTMVFDFKGQLKTGDLLLHSWSSFPDELEEMLNPMGTLQALLQI
WSKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELAQYLLQLVQVLKYEAFLDTALS
RFLLEKALANRRIGQMLFWHLRSEMHIPAVSLQFGVILEAYCRGSITHMKVLSKQVEALN
KMKTLNSLIKLNAMKQSKAKGKDTMHTCLKQSAYKEALSHLQSPLNPSVLLSELCIEKCK
YMDSKMKPLWIVYSNKVFGADLVGIIFKNGD
>A0A8C4U760|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Falco tinnunculus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSSLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHVFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFINIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTVIISDKYEGGA
>A0A0Q3M679|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amazona aestiva|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQEPEVHDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRTTTSVWDISNPFKITLLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMQTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A671SG71|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
LCFSFVVCAMPSAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLL
LWKEAQTYPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGR
AERILDSKIGVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYT
MPLEAGSLESLIDKHEDVIKITMHYDQSQVSSVNLVCITELMDQALKKWQTTHGPEEDIG
FRSDYVLRVSGKLEFLFEDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIG
SVIARKTSNPPLLLPPKKRLPTASTLIVCHVRAGLFHGTELLCKTAVSSESSSRSEHVWN
KTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHYPIAWVN
TMVFDYRGQLKTGDIILHYELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVFPVF
DKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRYDCREN
FPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVYCLR
DMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMFMPAVS
VHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFGTIKTKTKQAHLKEAMMTCL
RQTGFIETLSDLHSPLNPNILLAGINVERCKYMDSKMKPLWIVYNNKLLEGETVGIIFKN
GDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHAGLIEVVSSADTIANIQKT
SSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTSNTEKFGNFRQYC
EEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFD
EALRESWTTKVNWMAHIVAHPS
>A0A8C0B080|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Buteo japonicus|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSVSVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKVSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENARVHVRAGLFHGTELLC
KTIVSTEISGRSDHIWNEVLEFEISVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHVKFHEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRNLPGFESIYKLLNTSETDSLALGKSEEEALKQFKQKFDEALRE
SWTTKVNWMAHTVRKDYRS
>A0A3L8SI20|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chloebia gouldiae|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSTSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDSPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSNESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLGDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGN
LFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGISGKKTSVHFHKFQDVCVKAYLA
LRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDKG
WTVQFNWFLHLVLGIKQGVEKHSA
>A0A803YGT2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Meleagris gallopavo|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMELANIPTYLLQGWEGEY
FGLTVLPFIVSNGNLVASHFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYTLQV
NGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQVNSIANPPKMAVKP
PPLPKKKVKGHSQVPLVVQAGLFHGNEMLCKMVSSSEVNVCSEPVWKQRLDFDINICDLP
RMARLCFALYAVIEKAKKARSTKKKSKKAVSKDCPIAWVNVMLFDYKDQLKTGECCLHMW
SSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNVASHPVYYPSFEKEICSATDSSVMH
LLQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLTITKWNKHEDVAQM
ISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESY
LDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMK
QGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQETYLEALSHLQSPLNPSIILTEV
CVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEG
LDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPG
DALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGI
NRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYMILRRHGPLFLHLFALMKAAG
LPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3P8W8I0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cynoglossus semilaevis|TrEMBL
MPPAMTDLLDIWVAHSPMLGHTPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TLPLFTALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRNKIVRLSEERMQRVCLMTCTEWLQACFSPQLDPG
STTAVTDEVSEQSDLKVIIHFEQSQVRLYKPFCLILKLMDLAIKKWLTTHSPEEEASRSE
YVLRLSQCLEFLCGNHPLSQYKYIRTCMQAKESPSLTMVHMSTIKAMFDKEIKTIGAVVN
HKSLNPLPLPLPPKRRAPTVQVRAGLFHGTELLCKPVVSSESSQRSDHTWRESTLEFEIS
VCDLPRMTRLCFAIYAVMDKVKKQKSTKNPHLYKYQTIRKAGKVHFPIAWVNTMVFDYKG
HLKTGDINLHCWSSFPDELEEMLNPIGTVQTNPYTENATALCIHFPEYSSHPVVFPPFDK
ILEKAAEIVGASDCSPMGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRCDCRENFP
QSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLHDM
SDDELSQYLLQLVQVLRYEPYYDCALTHFLLRRAHGNRKIGHFLFWHLRSEIHMPAVSVQ
FALILEAYCRGSVPHIEVLKKQVDALSKLKSVNELIKHGNTKNARSKTKEAMLTKEAMMA
CLKQSGYSETLSDLCSPLNPSVMLSGINVEKCRYMDSKMKPLWIVYNNKLLMGDTLGIIF
KNGDDLRQDMLTLQILRLMDLLWKESKLDFRIVPYGCLATGDKAGLIEVVSSADTIANIQ
LTSSNMAAAAAFNKDALLNWLKERNSGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGCFRR
YCEEAYLILRNHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQK
FDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C7CJP6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
IELQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPTEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQALQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESALNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFN
IRIRDLPKGARLSLQVSCGKTQISKGTSSYQDNGGSPVGGGSGNHDCNKTKSRLLYYVNL
LLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYP
VALPKSREGERGQREMPNHLRKQFEAIVETDPLHPLSQEDKELLWHFREECMRHPRAYPK
LLGSVRWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLETL
GNDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQ
RYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQVVFQLRQKL
ENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTTLSSDTIGVI
FKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTIANI
QQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLGVGDRHNDN
IMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFQKFQD
VCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEEAQRHLLDQ
IEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>U3BGH4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callithrix jacchus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLNGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRTKMCQFCEEAAARRQQLSWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHFSSILAMRDEQSNPAPQVQKPR
SKPPPIPAKKPSSVSLWSLDQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISISDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLHMWPSVPDEKGELLNPTGTVRSNPNSDSAAALLICLPEVAP
YPVYYPPLEKILELGRHSECVRVTEEEQLQLREILERRGCGGLYEHEKDLLWKLRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLGALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSSGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C0IHW5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLERSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFENSLALLSLKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLL
IITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDQYVGSFAINSLKKLTDHELFQ
YLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEA
YCRGSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHVCMKQETYLEALSH
LQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTL
QMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFN
KDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHID
FGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHG
LLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKV
NWLAHNVSKDNRQ
>A0A8C0FTE3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLERSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQVGDQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIIT
KWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDQYVGSFAINSLKKLTDHELFQYLL
QLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCR
GSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHVCMKQETYLEALSHLQS
PLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMI
QLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDA
LLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGH
FLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLF
LHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWL
AHNVSKDNRQ
>A0A8C4G146|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPGVFGMQDVWEKDGQQVTVEFLLPTGIYLTLEVSCSDTIGTIKKMLWRAARGEPLFGA
LSDPDAYVFTCINLTAEREDLEDEQRRLCDVRPFLPILRLVAREGDRVEKLINTQISHLI
GKGLHEFDSQKNHEVSEFRTKMRAFCEERAQERQRLPWYEWMESSFPCDLEPCSGFELIV
IVIHCTESFMLQLDPQDLPVMLMKNALKKKATVFRPVRQEKPEDYTLQVLGRWEFIYGKH
PLCQFKYIWCCMHEAQTPYLTMVHHSTITKYQEEQSCLTNQVTKTRSSSKPPPLPLKKRK
LYDLRKHCWMLPVLTSFYSLFQLVVQAGLFHGSELLCKVVTSNEVNVSSEPLWDQKLVFD
ISVGDLPRMTRLCLALYAVVGTTKKARSTKKKNKRDCPLAWVNTMVFDYKDQLKTGDFSL
SAWPSVPDEKSDLLNPMGTVEKNPNIDSAAGLLIRFPNIRPHPLCYPPLDKAGLKTPHTS
IRPLYSDSLISMHGCLQHMKLKEIVDNKNQTEIFEDEKELLWKLRVEMRDHYPESLSKLL
LIGKWNKHEDVAQMVWLLRKWPDLPVLHALELLDYRFPDPYVRSFTIKCLRKLRDDELFR
YLLQLVQVLKYESYLDCDLTTFLLERALSNKNIGHFLFWHLRSEMHVSSASLRFGLILEA
YCRGNLYHIKTAVARSFWQNEALNKMKALNDFVKSGSQKATRSQTIEDMKVCIRQEAYME
ALSDMLSPLSPSIILSEICTEKCKFMDSKMKPLWLMYKSKVAQADTVGIIFKNGDDLRQD
MLTLQMLELMDVLWKREGLDLRMVPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAAT
AAFNKDALLNWLKSKNPGDKLEEAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQL
FHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYKIL
CRNGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKIFKVKFNEALRESW
KTKVNWMMHSVAKDNR
>A0A8C0IHA4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
MYSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQ
AHAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKL
DSKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEP
VIPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEV
DPADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIE
AAINRKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGT
ELLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMN
PSKYQTIRKAGKVHYPVAWVNTMVFDYKGQLRNGELVLHSWSSFPDELEEMLNPMGTVQT
NPYTENATALHIRFQEYSKQSINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFHIVLKE
IMERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPK
LLPREALELLDFNYPDQYVREYAVGCLKQMSYSVTDCFYVPHSSDEELSQYLLQLVQVLK
YEPFLDCALSRFLLERALANRRIGQMLFWHLRSEVHIPAVSIQFGLILEAYCRGSVAHMK
VLAKQVEALNKMKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVI
LSELHVEKCRYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILW
KEAGLDLRILPYGCLATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKE
YNLGDDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKS
KFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALM
LTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKD
YRS
>A0A6P7EK04|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ovis aries|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRIPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVCSQKTPKPQAKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ETAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7L3IZA7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Thalassarche chlororhynchos|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERQVFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8J4I3R8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Spheniscus mendiculus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEERGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERQVF
RGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFR
LKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C5I1N3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
LQFFVPIMVWKNARNEALFNGLGDPEGYVFTCINQTAVREELEEESRRIRDVRPFMCVLR
LVAREGDRVEKLTNTQISLLIGKGLHEFEAQKNHEVNEFRSKMRSFCEEKAQKRQGLPWQ
QWMEYSFPCDLEPCSAKSKNKKKIFINVKFEASDESFMLQQEPQDLPLALMRSALKKKAT
VFRSLRQEPEDYTLQVNGRWEFIFGKHPLCQFKQNTSSLWAINKPFNIHLLQGSRVNADE
GMKVSVRAGLYHGSELLCKVVTSSEVTVCSEPLWDQKLDFDINVADLPRMSRLCFALYAI
IEKAKKPRGTKKKNKKADCPIAWVNTMVFDHKDQLKTGEFLLSTWPSVPDDKSELLNPMG
TVEKNPNVDSAAGLLIRFPNILPHPLYYPPLDKPHLKRTTPFFRFVSQKKMYTKLKEIMD
NKNHTEFFEDEKELLWKLRTDIRDCYPESLSKLLLITKWNKREDVVQMVSLLESWPELPA
IHALELLDYSFPDPAIRSFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCVLTTFLLER
ALANRRIGHFLFWYLRSEIHVASVSLRFGLILEAYCRGNIHHMKVLTKQNQALVKMKALN
DFVKSGSQKMTVEDLRLCVKQESYMEALSDLLSPLNPSVILAEICADKCRFMDSKMKPLW
LMYRNPWPHADMLGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNK
MGLIEVVKNSDTIANIQLNSSTSAATAAFNKDALLNWLKSKNPEDKLEQAIEEFTLSCAG
YCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHV
IQQGKTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDS
LALGKSEDEALKNFKVKFTEALRESWKTKVNWMMHSLAKDNRP
>A0A673ICN1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYSMPLEAGSLE
NLIDKHEASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGFRSDYVLHVSGKLEFLFEDH
PLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIGSVLARKTSNPPLPLPPKKRL
PTIQVRAGLFHGTELLCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVM
DKVKKPRSTKNTHLNKYQTIPWVNTMVFDYRGQLKTGDIILHCWTSFPDELEEMLNPIGT
IQTNPYTENATELHINFPEYSTQPVVFPAFDKCMHRKQLKEIMERDPLSQLCENEKDLIW
TLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYV
REFAVYCLQDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERSQSSRKIGHFLFWHLR
SEMFMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFGTIKTKTKQAH
LKEAMMTYLCVCTYMDSKMKPLWIVYNNKLLEGDTVGIIFKNGDDLRQDMLTLQILRLMD
LLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNW
LKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGN
FKSKFGIKRERVPFILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLF
ALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIV
AHPS
>A0A673IPH3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSAELPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKITHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDEYLLEKHPLSQYKYIRSCITLGRLPHLMLVSKDSLYSQLPSS
GFMAPSYSRRTPQPSPCPGGGDPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDEQQIEEHANWKSVLEMECGFSSSRLVCDSSISQADAEQLRTLCSRDPLYE
LSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVHNLDIFLRWKNAVLQMLETWLS
KERLLSNSTPRFLTDDEELTEQPSSLRQCSRLLYAEVLCLIINTSVFSEFMMSPSSPITE
TADWLMKLILHSDWLLQTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIM
SSAKRPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLR
MLPYGCLSIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIRDKNKGEAYDR
AIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERV
PFVLTQDFLIVISKGVQECTKTKEFESKKGNCDFFPLIIDFFSQNCEI
>A0A673J336|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMRDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGLCHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWDQWMEYNFTCDLEPCSVVA
QSGKSSPGYAFHIFTLKKSTVFRSAKQEKPEDYTLQINGRWEFIYGKYPLCQFKVSLKIT
PSSRLHSYIFFKLHIKASHFQTPGCMSFIYLVLLFSLQSLSFSQLVVQAGLFHGSELLCK
VVTSNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCIALYGVIEKTKKRPTKKKNKSSDCP
LAWVNTMVFDYKDQLKTGEFSLSTWPSVPDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPH
PLYYPPIEKTLILTNGTVFFQHLKLREIVDNKNYTEFFEDEKELLWKLREEVRQRYPESL
PKLLLITKWNKHEDVAQMVGLLQKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLRDD
ELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVSSVSLRFGL
ILEAFCRGSIFHIKNLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYME
ALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDTLGIIFKNGDDLRQDMLT
LQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAF
NKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHI
DFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRN
GTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTK
VNWMMHTFAKDNR
>A0A673LHK7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
VSLQNFKFIVRREENKRRRRKMKAFTSTSAVSTDHIAVEFVLPTTNKNSRNPDTLHIDVT
GNWTVEQVKVQIWHRAVTTKLYLKTLLASVFVLLTSKQLWYEIYDKQQVFQTLDCIRYWK
ALRKEVGKIHLVVRTQPTEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRKLLTPRKI
ELSDRDPKLYSMDPWMTTKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDDTPVQVLQ
SFFAKITNKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKNGEEIHLV
LERPPDPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRKFRVKIL
GIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIKIKDLPKG
ARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVDHRSLLRQGEFILHMWKMPEKSE
DNSSVNADKLTSATNPDKNSSMAVAILLDQYCYPVALPKSKDSPDSEMEGERGQREMPNH
MRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEAVTITHRL
LERSTVWDRSSLDVGLALQLMDCHFSDENVRTMAVRKLETLAGDDVLRYLLQLVQAVKFE
PYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGEAMLQ
DFRKQVEMTEALHKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDSFKVPYDPG
LRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDMLILQILLI
MESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDEILSQW
LREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDFGHILG
NYKSFMGISKERVPFVLTPDFLYVMSTTGKKSSPHFLQFQSVCLKAYLALRHHTNLLIIL
FSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQFNWFLHL
VLGIKQGVEKRSA
>A0A673IYA3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMRDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWDQWMEYNFTCDLEPCSVVAQS
GKSCSDKKIFVNVKFEGSEETFVLQQGPQDLPMFLKRNALRKKSTVFRSAKQEKPEDYTL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRVRRHFYTGTRSLVVQAGLFHGSELLCKVVTSNEVSVCSEPVWDQKLVFD
ISVSDLPRMSRLCIALYGVIEKTKKRPTKKKNKSSDCPLAWVNTMVFDYKDQLKTGEFSL
STWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKLNELGMNGE
KTVATKEEHLKLREIVDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHE
DVAQMVGLLQKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLRDDELFQYLLQLVQVL
KYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVSSVSLRFGLILEAFCRGSIFHI
KNLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSI
VLCELCADKCKFMDSKMKPLWLMYKNKYDTLGIIFKNGDDLRQDMLTLQMIQLMDVLWKT
EGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKN
PGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSKF
GINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMKA
AGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A8J4JZT3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eudyptes sclateri|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCMSGNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQKRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGNRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEVVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A673MT57|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQS
GKSHSGKKILVNVKFEGSEVSEQDPQDLPMFLKWNALRKKSTVFRSAKREKPEDYTLQVN
GRWEFIYGEYPLCQFKVSLKVTTSSRLHSYIFFQIYMKQNTSSLWSIHEPFYIYLLQGSR
VNADEGMKLVVQAGLFHGSELLCKVVTSNEVSVCSEPVWDQKLVFDIGVSDLPRMSCLCF
ALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPGDLLNPM
GTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKVCCYKRREIVDNKNYTEFFEDEKELL
WKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPH
VRSFTIRCLRIFNDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLR
SEMHVPSVSLRFGLILEAYCRGSIFLIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTT
EDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKDKYDHVGI
IFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIAN
IQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERF
RECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFK
VKFNEALRESWKTKVNWMMHSFAKDNR
>A0A852PQ31|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Atrichornis clamosus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSNFSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQATDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSEVDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDVTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNTWLEFDIKI
KDLPKGALLNLQIYCGKAQGASAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAVSIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPEGFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K9M7E2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oceanodroma tethys|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYSFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVESPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKREDVAQMISLLQTWPELPVLNALELLDFSFPDCYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDLVKASSQKATKPHTKEVMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C4VKJ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gopherus evgoodei|TrEMBL
MELGNYEQPVVMREEAKRRRRRMKPHSPASNLSSVELISIEFILPTSNKQVQETMLLEIA
GNCTVEQMKAQIWMRAIEMSQTTDFYHKFAPDQFILQYQKKGQWYEIYDKHQVIQTLDCI
LYWKVLQKKVGKISVIQKQKPAQAVQEFQTQLNDLIGYDVTDVSNVHDDELEFTRRRLVT
PRMIEVACRDPKLYSMHPWITSKPLPEYVLKKITNNNIFIIIHRGTTSQKIKVSIDDTPD
MILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNGEE
IHLVLDDPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRKFR
VKIVGIDIPVLPRNTELTVFVEANIQHGQQLLSQRRTISKPFTEEVLWNTWVEFDIKIKD
LPKGALLNLQIYCGKAQALSTKVNLQSHDSPNSDSKCKTQLLYYVNILLIDHRSLLRSGE
YVLHMWKISGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSDPQ
GDRTRAEMPNQLRKQLEAIIDTDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWG
QQEIVAKTYQLLAKREAWDHSSLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVLHY
LLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEA
YLRGCGKAMLHDFMKQVQIIKLLHKVTMDIKSVSAEKYDVTSQVITQLKQKLEKLQNSKL
PESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLR
QDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNT
GAFKDEILNQWLKDRCVIEEKFQAAVERFVYSCSGYCVATFVLGIGDRHNDNIMITESGN
LFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTTGKKTSMHFSKFQDICVKAYLA
LRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDKG
WTVQFNWFLHLVLGIKQGVEKHSA
>A0A5N4DZH2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Camelus dromedarius|TrEMBL
MLPKFGPISFQVAQGMELENYEPPVVLREDNCRRRRRMKQRSTAASLSSMELIPIEFVLP
TSQRNTKTPETALLHVASHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQ
WYEIYDKYQVVQTLDCLRYWKVLHRSPGQIHLVQRSMPSEETLAFQRQLNALIGYDVTDV
SNVHDDELEFTRRRLVTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIH
RSTTSQTIKVSADDTPGTILHSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGET
PIKNFQWVRQCLKNGEEIHLVLDTPPNPDLDQVRKEEWPLVDDCTGVTGYHEQLTIHGKD
HESVFTVSLWDCDRKFRVKIRGIDIPILPRNADLTVYVEANIQYGQQVLCQRRTSPKPFT
EEVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSGKASAETPSPESKGKAQLLYYVN
LLLIDHRFLLRHGEYVLHMWQLSGKGEDHGSFNADKLTSATNPDKENSMSISILLDNYCH
PIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKD
PKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAV
QKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQ
SRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIS
QLKQKLENLQNLNLPQSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSN
ETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDA
TTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIDEKVGSCFSPP
>L5LGX6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myotis davidii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWGINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLEMEFDWF
SSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDP
LSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAM
ELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDIL
KQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A091MR56|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acanthisitta chloris|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPMKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGKLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKVKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>I3J294|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKSKNIKKIFINVKFEASDESFMLQQDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTITKYQEEQGRMCSQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKICDMERNGDLSLANKEEYFKLKEIMDNKNYTEFFEDEKELLWKLRTEVRD
HYPESLSKLLLITKWNKREDVVQVRMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIR
CLRKLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVA
SVGLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQE
SYLEALSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDD
LRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSN
SAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERA
YKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>I3JX49|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MAPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLTTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYSKLDKGQIIVVIWVIVSPTNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPME
FFTMPSYARRISTATPYMNGETATKNLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLTYDMYIPEVPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHY
SSPVKFPDMSTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHDCINMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMVREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTILKFHLLSS
>A0A7L0J0M7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Piprites chloris|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGC
LQTPTKNIFVNVKFQSGGESFTFQISPKEFPLTLMSYAIKKQATVFRHETVQKPEDYTLQ
VNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMAPK
PPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSE
VNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWVN
VMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A2K5NL75|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cercocebus atys|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNP
TGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKLLGGMLLASRGWRPELPWICLHARD
SAPSRMMGVATPCLGVLPGLVQALGDAECSCLLQILELGRHSECVHVTEEEQLQLREILE
RRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPV
LSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDR
ALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSSGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C8CF93|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPAMTNLMDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLTFEVHHTMSLCVD
VNEDNVLSLQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEEGRQAEQYVLRVSDKLEF
LCGDHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISAIGAVVNRKSSNPPLPLP
PKRRGPSVSQTVSTHFKIVLIKGSKVNAEETAKIQVRAGLFHGTELLCKPAVSSESSGRS
EHVWNRTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKSTKNAHINKYQTIRKSGKVHYP
VAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPIGTIQTNPYTENTTALHIHLPD
YNPHTILFPPFDKILEKAAEIAGSSDCLPMGRGGKKFHIELKEIMERDPLSQLCENEKDL
IWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQ
YVREYSTRSQTRSHITIPSSLTVVIDEELSQYLLQLVQVLRYEPYYDCALTRFLLNRAQC
NRNIGHFLFWHLRSEMHMPAVAVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELI
KLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMD
SKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYG
CLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
THDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A7K7AWP7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothoprocta ornata|TrEMBL
MPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWQHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRIKMRQFCEERAAKRQQLNWAAWMEYNFPLQLEPLAKGFGT
GPLQTPTKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIANPPKMT
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSIAS
HPVYYPSFEQLLELGRNGEQPRAALEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
VRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPILNALELLDFSFPDRYVGSFAI
NSLKKLTDGELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVEQCTFMDSKMKPLWIVFNNEDTGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALAKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7M4F9I3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crocodylus porosus|TrEMBL
MFPAPSPGAQWGSTVMPCTVVLDCLLPNGVMVSLESPRTASLLTLKHRLFQEARKFPLHH
LLQDESRYVFLSVTRDAKREAFFDEMRRLCDLRLFHPFLKVVESTCDREEKILNQEIGTA
IGMPICELEAAKDPEVQDFRRNMLGVCKEAVELRGADPPHSRALCVCTPNVDSSPELPRP
LYDKLDAGQLRVVIWFITPQSNKQKYRLKINHDCVPEQVIVEAIRKRGRNMLLSPEQLKR
CVLEYKGNYVLKACGCDEYLLENYPLSQYKYIRHHIMVGLVPNLMLMTKGSLYEQLPLDT
FKMPYYSTRVCPDTPYVNIDASAKSLWSIKTNLRIRILCATYVNVNTQDVAKIYVRTGIY
HGSELLCDCENTQSVPCSDPSWNEWLSYDMRVSDLPRASRLCLSICSVKERKDVKEEHCP
LAWGNINMFDYMHTLVSGKMALHLWPVPHALDILLNPLGVTGSNPKKATPCLELEFDWFR
GPVKFPDMTVVEDGGMKALSLELGYNCSHTVLSKRLARDAEVRESDKEQLCALCARDSLS
EITEQEKDFLWSHRHTCMNIPEILPKLLLSVKWSSRHAVAQMYCLIKHWPPIKPEQAMEL
LLCNYPDPLVRSFAVQCLEKYLTDDQLSQYLIQLVQVLKYEPYLDNLLVRFLLKKALTNQ
RIGHFFFWHLKSEMHNRVVRQRFGLLLESYCRACGTYLKHLTRQVEAMEKLINLTDILKQ
EKKNEVPKVQMKFIVEQMRQPDFMETLQGFISPLNPAHRLGHLRLEECRIMSSAKRPLWL
SWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIQIMENIWQNQGLDIRMLPYGCLSI
GDCVGLIEVVRSSHTIMQIQCQGGLKGALQFNSHALHQWLKDRNQGEKYDAAIDLFTHSC
AGYCVATFVLGIGXXXXAKGVQRRGAQRPPAPSLYFAALCPSPQVISETWA
>A0A2Y9GP77|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neomonachus schauinslandi|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTVRVPTRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFRVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEELQLREILERRGSGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALSDFVKVSSQKTTKPQTKELMHLCIRQ
ETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDTQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A2Y9GKH9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neomonachus schauinslandi|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTVRVPTRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPRTKPPPIPMKKPSSLSLWS
LEQPFRVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSVCSEPVWKQRLEFD
INICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGECC
LYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAPYPVYYPTLDKILELGRHG
EHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQERFPEALARLLLVTKWNKH
EDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQV
LKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHH
MKVLMKQGEALSKLKALSDFVKVSSQKTTKPQTKELMHLCIRQETYLEALSNLQSPLDPS
TLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNGDDLRQDMLTLQMIQLMD
VLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNW
LKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGN
FKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLF
ALMRAAGLPELSCSKDTQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNV
SKDNRQ
>A0A6J0D4H7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Peromyscus maniculatus bairdii|TrEMBL
MPPGVDCPMDFWTKEESQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEVAAHRQQLGWEDWLQYSFPLQLEPSARSWRA
SILRVTNRALLVNVKFEGSEESFTFQVSTNDMPLALMACALRKKATVFRRPLVEQPEDYA
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPAKKPSSVSLWSLEQPFCIELIEGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVICLPEVAP
HPVYFPALEKILELGRHGERGRVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMR
QETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C9UMJ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Spermophilus dauricus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMYIRSCIMLGRMPNLMLMFPDVSVIEEHANWSVSREAGFS
YSHAGLSNRLARDNELRENDKEQLRAICTRDPLSEITEQEKDFLWSHRHYCVTIPEILPK
LLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDK
LSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLL
LESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDA
LQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDL
RQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLK
GALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDG
QLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKA
YLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAH
HGGWTTKMDWIFHTIKQHALN
>A0A5F8GEL2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodelphis domestica|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVHAPHSRALYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASTKSLWVVNSALRIRILCATYVNVNIRDIDKIYVRTGI
CHGGEPLCDNVNTQRVPCSNPRWNEWLMYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMAVIEEHANWTVSRELGFNYSHAGLSNRIARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVSIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLT
LQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFN
SHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHID
FGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQ
HANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTT
KMDWIFHTIKQHALN
>A0A7L1N550|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinopomastus cyanomelas|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNWSSMELIPIEFILPTSNKHTKLPEIVLLE
IAGNCTVEQMKAQIWMRAIEMSQSTDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQNPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGMTSQKIKVSIDDT
PDRILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDHPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKVIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLPSHESSNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIMSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRHKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGM
>Q5F3P4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gallus gallus|TrEMBL
MPRGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLDTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPIKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQVNSIANPPKMA
VKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNMCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNVAS
HPVYYPSFEQLLELGRNGEQPRSAPEDPEEKLQLKEILERRNHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLTITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHV
CMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGGDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCEKAYMILRRHGPLFLHLFALMKAAGLPELTCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3P8YLC8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MAKQVSDEDLHSVVHREENRRRRRKMKAFTSTFSVIMDQISIEFVLPTSTKSSRSPDTLL
LEVAANWTVEQVKAQVWLRAVASNLCPEFYQKFSPDHCILLYQKKGNWCEIYDKHQVFQT
LDCIRYWKALKKDVGKIHLTCRPQPSEDSVRYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLFSPRRIELSDRDPKLYSMDPWITSKPLPDISCLTVSTASQTIKVSIDDTPVQVLQTFF
AKIANKRALLGIPDDMCEADYVLRVCGREEYIYGNHPVRDFHWIRQCLKNGEEIHLVLES
APNPEQDQVQREDWAQVDDCTGVAGTHEQLTIEEKDHERVFTISLWDCSRKFRVKVLGID
IPTLPRNPELIVFVEASIFHGQQLLAQERTTSKAFTEEVLWNTWLEFNIRIRDLPKGSRL
SLQVNVLYHSVTPSLTRRHSLLTKSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPEKTED
NSSVNADKLTSATNPDKASSMALAILLDKYCYPVALPKSRESKEPGGDGRSAEGGERGLR
EMPNHLRKQFEAIIETDPLHHLSPEDKELLWHFRQECMRHPSAYPKLLSSVRWGRQEAVL
ATHRLLERSTVWDRSPLDVGLAMQLLDCHYSDANVRSMAVRKLETLGDDDVLRYLLQLVQ
AVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIATSMHYQQRYAVLLEAYLRGCG
DDMLQDFRHQVEMTEALQKVTREIKTMSAEKYDVSAQVVFQLRQKLENLQTSGLPESFRV
PYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTRSSDTIGIIFKDGDDLRQDMLIL
QILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSVVGSTGAFKDE
ILNQWLQDKCVNEEKFQQAVERFVFSCGGYCVATYVLGVGDRHNDNIMITESGNLFHIDF
GHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFLKFQDVCVRAYLALRHHTN
LLIILFSMMLMTGMPQLTSKEDIEYIREALTVGHPEEEAQRHLLDQIEICRDKGWTVQFN
WFLHLVLGIKQGVEKRSA
>A0A1U8C7V2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mesocricetus auratus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVDDFRTKMRQFCEEVAAHRQQLGWEDWLQYSFPLQLEPSARSWRA
GILRVANRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEDYA
LRVNGRHEYLYGNYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPAKKPSSVSLWSLEQPFCIELMEGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAP
HPVYFPALEKILELGRHGERGHITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDSYVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMR
QETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGRAGSVGIMFKN
GDDLRQDTLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGQLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A1A8FXA0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius korthausae|TrEMBL
MPPGKYGMQEEWEKEGDQNILMDFLLPTGIFLKFPVPRNDTIKNIKKMVWRNAKTEALYC
GLGDPEGYVFTCINDTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNSHISSL
IGKGLHEFEAQKNHEVDEFRSKMRTFCEEKALERHNLPWQQWMEYSFPCDLEPCYSPPVH
GGTKSKHTKKLFINVKFEACDESFMLQQDPLDIPVALMKSALKKRATVFRSVRQEPEDYT
LQVSGRWEFIYGNHPLGQFKYIFSCLRNGQNPQLIMVHHSTISKYQEEQGQLCSQMGKIR
SQSRPPPLPMKKQNT
>A0A3Q0D6M9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mesocricetus auratus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVDDFRTKMRQFCEEVAAHRQQLGWEDWLQYSFPLQLEPSARSWRA
GILRVANRALLVNVKFEGSEVSTKDMPLALMACALRKKATVFRQPLVEQPEDYALRVNGR
HEYLYGNYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRTKPPPI
PAKKPSSVSLWSLEQPFCIELMEGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVSVC
SEPVWKQRLEFDISICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAWANLMLF
DYKDQLKTGERRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAPHPVYFP
ALEKILELGRHGERGHITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQERFPEAL
ARLLLVTKWNKHEDVAQLSQMLYLLCSWPELPVLSALELLDFSFPDSYVGSFAIKSLRKL
TDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALR
FGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQET
YMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGRAGSVGIMFKNGDD
LRQDTLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSN
MAATAAFNKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRE
SGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERA
YTILRRHGQLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEAL
RESWKTKVNWLAHNVSKDNRQ
>A0A2R9CFV4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan paniscus|TrEMBL
MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7K8NIF9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Casuarius casuarius|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWQHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRIKMRQFCEERAAKRQQLSWAAWMEYNFPLQLEPLAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIANPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVHCNPNTESAAALVICFPSITS
HPVYYPSFEQLLELGRNGEQPRTALEDPEEKLQLKEILERRSHTELYEDEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDGELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVEQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALAKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C6ZKI4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothoprocta perdicaria|TrEMBL
MPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWQHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRIKMRQFCEERAAKRQQLSWAAWMEYNFPLQLEPLAKGFGT
GPLQTPTKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETMEKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIANPPKMT
SKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSIAS
HPVYYPSFEQLLELGRNGEQPRAALEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
VRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPILNALELLDFSFPDRYVGSFAI
NSLKKLTDGELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVEQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDGKDLNQDCDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGEA
LEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINR
ERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLP
ELSCSKDIQYLKDSLALAKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K5HY03|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crotophaga sulcirostris|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGVSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLDDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C7SH39|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRTKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVV
TSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPHFDKPTSYICNHYTCNHLLKEIVDNKNYTEFFEDEKELLWKLRGVVRERYPE
SLSKLLLITKWNKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLR
DEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRF
GLILEAYCRGNIYHIKSLCKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAY
MEALSYLLSPLNPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDTVGIIFKNGDDLR
QDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSA
ATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETG
QLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYK
ILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDSRL
>A0A8C7UW75|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MEQQVSDEEESQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKHLPEYLLFCIGHILLVIHRNKASQTIKVSIDD
TPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCLKN
GEEIHLVLESAPNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDCHR
KFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFNIR
IRDLPKGARLSLQVSCGKAQTQISKGTSSYQDNGGSPVGGGSGSHDCNKTKSRLLYYVNL
LLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYP
VALPKSREGKEAGGEGREAEGGERGQREMPNHLRKQFEAIVETDPLHPLSQEDKELLWHF
REECMRHPRAYPKLLGSVRWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDA
HVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWF
LRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYD
VSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVVKQCKVMASKKRPLWLQFKRA
DPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGM
IEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVA
TYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTS
GKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVG
RPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A8C2ZU19|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
VELDDLPDDEEPKVLREDTRRRRRKKAISSSSGASMDQITVEFVLPTAARGGSGPDTLPL
EVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTL
DCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRRIELSDRDAKLYSMDPWVTRKPLPEHLLTKVSNAHVLMVIHIRTASQTIKVSIDD
TPAQVLVSFFAKTANKRVLLGIPDSMCEADFVLRVCGRFVGDSVFNGWYPTCLKTVFDDV
CNPSAPFRGNNSPANLSLSGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVLGIDIPSLP
KIPEFIVFIEASIFHGQQLLAQERTSSKTFSEEVLWNCWLEFNIKIKDLPKGARLNLQVV
CGKQPLTPNSKGTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEESSSSINADKL
TSATNPDKASAMAVAILLDKYCYPVVLPKSRNAGNRDDGGRDREMPNHLKKQFAAIVATD
PLHPLSPEDKELLWHFRHECIRDPRAYPKLLGSVRWGRQEDVLATHRLLERSSAWDSSGL
DVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLL
KRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRKQVEMTEAL
QKVTREMKAMSADKCDITAQVVFQLRQKLETLQLSGLPESFRVPYDPGLRAGALMIEQCK
VMASKKKPLWLQFKRADPTTLSRDPIGIIFKDGDDLRQDMLILQILLIMESIWETETLDL
CLLPYGCISTGNRIGQIFSADH
>A0A8C3A4L7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFAEARKYPLYH
LLQEESSYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSHALYVYPPNVESSSQLPQH
IYRKLDKGRLIVTIWVIVSPSNSKQKYTLKVNHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLAYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGVSSRLACDSRTSAADAEQLHSLSSRDP
LYELSEQEKDFLWRHRHYCVNMPESLPKLLMSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERSRNTGPCFTKGKGIMVPNYSNHGNAIMKYY
>A0A060YEM1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
LWFFSSTWLLSLTVLFPPPRSLWLSWVLVPAMPPAMTDDLDLWAAHSQLCGEDLVTVDFL
LPTGIYIQMDVPREATIQHIKLLLWKQAQSYPLFPSLGEMEGHMFECVNQAAVHEELEDE
TRRLCDVRPFCPMLKLVTRNCGRAERLLDSKIGVLIGKGLHELDALQDQEVKDFRSKMFR
ISEEKMQRVQLMTWSEWLQACFSPQLEPGGGATPVTDGVNDKQAEASLKVTMHFDQSQDT
ASLKVWPSTSPSELMEQALRKWLTTHGPEEEGRQAEQYVLRVSDKLEFLCGDHPLIQYKV
TPYS
>A0A0N8K1Z9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MPPRIFVDCLLPNGMILTLECLREATLITIKHELFKEARKHPLHHLLQEETSYIFVSVTQ
EAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPE
VQDFRRNILNVCKDAVDLRDAGGPHSRALYVYPPNVESSPELPKHIYSKLDKGQIIVVIW
VIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQGKYILKVC
GCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDNFTMPSYARRISTAT
PYMNGEASTKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQMCDNVNTQR
VPCSNPRWNEWLQYDMYIPDIPCAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHT
LVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYFSCPVKFPDVVTIEDH
ANWIISRELGFNYSQSGLSNRLARDNVLMDSDLEQLRLVCNRDPLSEITEQEKDFLWRHR
HYCVNIPEILPKILLAVKWNSRDEVAQMYYLLKEWPAIKPEQAMELLDCNYPDPMIRDFA
VRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEM
HNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFL
VEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQ
NNEMIFKNGDDLRQDMLTLQIIRIMESIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSH
TIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDLAIDLFTRSCAGYCVATFILGIGD
RHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECTKTR
EFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEA
LDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A852N7A8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pteruthius melanotis|TrEMBL
MPPGIYCPSEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLGWTAWMEYNFPLQLEPVAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAVKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGRTPHLTMVHSSAIIAMRDEQNNCIASPPKAA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLDFDINISDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKVQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A5N5MVU7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pangasianodon hypophthalmus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLVTIKHELFKEARKFPLHH
LLQEEASYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESSPELPKH
IFGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMD
TFTMPSYSRRISTATPYMNGEASSKSLWTINSNLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLMYDMYIHDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SCPVKFPDMATIEDHANKIMSREMGYNYFQTGQSSRQARDHHIMEGDIEQLRQVANRDPL
SEITEQEKDFLWRHRQYCKNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLGRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGETYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A6J8C2C3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mytilus coruscus|TrEMBL
MRYIITIEGFQLTAICYHSTYRLNVLSGWLNVDDSLHELQTANDLGQLDIDFLLPNGICV
PLQVDIDRPLDQIKQELWKQAANYPLFQQLATFDKYGFLYISSEGLKEDVMDESVGIAEL
RLAASFLKVVEKPADDKRKTIDRQINSLIGMKGSNYIQAQHSVSKAEISEFRQKMTTYCN
NDILKQANQDPTGLVYFEYKHPCRLRSTRDLPPDVENFVINHIVLTVIVEEIGASYKLKV
NKMSTPDELVKMTVDKWSSKSGLKTKDCNDYILQVLGMKDFLYGDNPLVMFKYVYSCIVK
NTAPEFWLKTKSSVVEKQEVSQPHKSSRSSFQEERRNTVRSEKRSGHCVWDIHNNFYITL
HTACNVQVPENCRSLVRLCVGVFHGPDPLCSIQETKEVSVSQDGLCSFNDCINFDIKVQD
LPQMSRLCFGLHSKKGKEPLLLAWANIPIFDYKSNLQKGKLKLPLWPRSELIQQEESYCF
PVGTVATNPQGDCSMIEFSVPDFTKKGSIYYPPIEKVLQCASDHMEEPGKCGSPVLELAS
THIEVPGMPGSTTWRPNKNIVQQLDSILKANQYTVIQMLDEQQKQLIWWMRYDIRDKFHE
FPHALLYVLYSVSWDNHIEVSKMQALLQTWPTLEADQALTLLDFTFPDKYVRKKATEWLD
ELTDEELAQYLLQLVQALKYENYLNCDLVKFLLRKALQNRNIGHKLFWLLKSDMHDPSVT
VQYGLIIEIYLKANPSHMSILDRQQIILQKLKSITEIHTKATNLKKKGKEKDDSPLQKVM
QMGAYKEAFCNIYSPITLMYKLDKIVEKSCKVMDSKKKPFWLEWTNADEKGQNIQLIYKC
GDDLRQDMLTLQILEVMDTIWQSEGYDLRLNPYGCVATGNEEGMIEVVQKSLTLAGIQKW
RKQGLDKNSLYDWLKHKNPSEHSLQRAVEEFKLSCAGYAVATYILGVGDRHNDNIMMKET
GQLFHIDFGHFLGNKKTKFNIRRERVPFILTSHFEYVIKDGEKKPQNFHDFKDICERAYL
IIRSRAPLLIQLFMMMLSSGIPQLNNVSDIDYIKEVLALNSTQDEALEKFRKKFKEAQDN
SWSTTVNWWFHMRAH
>K7G7C8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pelodiscus sinensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIILGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWAINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTHTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMTVIEEHANWTISRELGFNYSHAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPLVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMHYNLLMILPTYERRL
HWTKVNKKL
>A0A3Q4G4B7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neolamprologus brichardi|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVIRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRCKMFRISEERMQQIQMMAFSEWVQACYSPQLEPA
AVTAITAGVNDAPVDLKVIIHFDQSQDSASLKVSLSCTPNELMEQALKKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKEAPHLTLVHTSTVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRRIFCLSLHLWPLADWLAIVKFNPSCRTQVQVRAGLFHGTELL
CKPAVSNESSGRSEHTWKDNTVEFEISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNPHIN
KYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATALHIHFPEYSSHPIVFPPFDKILEKAAEMVSADCVSIGRGVKKFYMELKEIMER
DPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQVRKHIHCYGLLDFN
YPDQYVREYAVRCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQRNRQIGHF
LFWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQVEALSKLKSVNELIKLGTIKN
TRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDINVEKCRYMDSKMKPLW
IVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDR
TGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFTLSCAG
YCVATYVLGIGDRHSDNIMVRSNGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHV
IQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDS
LALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A672LGG3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDGTRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYSMPLEAGSLE
NLIDKHEASLKVSLHCTVTELMDQALKKWQTTHCPEEDIGFRSDYVLRVSGKLEFLFEDH
PLNQCKVRYVVHSLFRINLVKGNKVNAEDAAKIQVRAGLFHGTELLCKTAVSSESSSRSE
HVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIPWVNTMVFDY
RGQLKTGDIILHCWTSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVFPAF
DKGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKH
EDMTQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVYCLRDMSDDELLQYLLQLVQV
LRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMFMPAVSVHFALILEAYCRGCIPH
IEVLKKQVEALSKLKAVNELIKFGTIKTKTKQAHLKEAMMTYLCVCTYMNSKMKPLWIVY
NNKLLEGDTVDIIFKNGDDLRQDMLTLQILRLMDLLWKEAKLDLRIVPYGCLATGDHSGL
IEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCV
ATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQ
GKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLAL
GKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A672LED1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDGTRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYSMPLEAGSLE
NLIDKHEGIIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHCPEEDIGFRSDY
VLRVSGKLEFLFEDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIGSVLAR
KTSNPPLPLPPKKRLPTQLHTCVWKVHSLFRINLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWTSFPDELEEMLNPIGTIQTNP
YTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMTQLQALLQIWPKLSP
RDALELLDFNYPDQYVREFAVYCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLER
AQSSRKIGHFLFWHLRSEMFMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVN
ELIKFGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGINVERCKYMNS
KMKPLWIVYNNKLLEGDTVDIIFKNGDDLRQDMLTLQILRLMDLLWKEAKLDLRIVPYGC
LATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
HDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A672R6D7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPGVYGMQDVWEREGWQQVNMEFLLPTGIYLNFTVTSSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWDQWMEYNFPCDLEPCSVVAQS
GKSCSDKKIFVNVKFEGSEVSPQDLPMFLKQNALRKKSTVFRSAKQEKPEDYALQINGRW
EFIYGKYPLCQFKVSLKITPSSRLHSYIFFKFHIKVSHFQTPGCMSFYILSYCFASFFFN
ILHFAQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSNEVSV
CSEPVWDQKLVFDISASDLPRMSRLCIALYGVIEKTKKKKSLSSCYTRIVFDCPLAWVNT
MVFDYKDQLKTGEFSLSTWPSVPDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPP
IEKTLLLRNVFFQHLKLREIVDNKNYTEFFEDEKELLWKLREVVRQRYPESLPKLLLITK
WNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLRDDELFQYLLQ
LVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVSSVSLRFGLILEAFCRG
SIFHLKNLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSP
LNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDTLGIIFKNGDDLRQDMLTLQMIQLMD
VLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNW
LKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGN
FKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLF
ALMKAAGLPELSSSKDIQYLMDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTF
AKDNR
>A0A672R5N0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPGVYGMQDVWEREGWQQVNMEFLLPTGIYLNFTVTSSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGLCHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWDQWMEYNFPCDLEPCSVVA
QSGKSCSDKKIFVNVKFEGSETDIFSQGPQDLPMFLKQNALRKKSTVFRSAKQEKPEDYA
LQINGRWEFIYGKYPLCQFKVSLKITPSSRLHSYIFFKFHIKVSHFQTPGCMSFYILSYC
FASFFFNILHFQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDISASDLPRMSRLCIALYGVIEKTKKRPTKKKNKSSDCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLY
YPPIEKVNVFFQHLKLREIVDNKNYTEFFEDEKELLWKLREVVRQRYPESLPKLLLITKW
NKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLRDDELFQYLLQL
VQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVSSVSLRFGLILEAFCRGS
IFHLKNLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPL
NPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDTLGIIFKNGDDLRQDMLTLQMIQLMDV
LWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWL
KSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNF
KSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFA
LMKAAGLPELSSSKDIQYLMDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFA
KDNR
>A0A8C2ND99|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Capra hircus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLXKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDXXXXXXXTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C2RE34|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Capra hircus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRIPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVCSQKTPK
PHAKEMMHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEA
GSDGTVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVV
LHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYV
LGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTN
NSEKFERFRGYCETAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTE
EEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C6MQE4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus spicilegus|TrEMBL
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLD
CLHYWKLMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIANNCIFIVIHGGTTSQTIKVSADDT
PGTILQSFFAKMAKKKSLMNIPESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
DEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPSLSSKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRHGDY
VLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSNLP
ESFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGSSGKKTSPDCCVYFTVLWGCLR
>A0A0D9RFE7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chlorocebus sabaeus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A672HG62|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salarias fasciatus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKCLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNDQLRQVCNRDPL
SEITEQEKDFLWRHRHDCTNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQQAMK
>A0A672H0V0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salarias fasciatus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQLDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRIKMFRLSEERMQRVQMMTCTEWLQACFSPQLEPP
AATAVTDGVNDRAADLKVIIHFDQSQDSASLKVPSCYTPAELMEQALRKWVTTHGPEEEA
WGGQHVLRVSHCLEFLCGDHPLIQYKVSRGTWPPHLTLVHTNTVKAMFDKEMTAIGAVVS
RRSSNPPLPLPPKRRVPTTCVWDVSSPFKIVLVKGSKVNAEETAKVQVRAGLFHGTELLC
KPAVSSESSGQRASSEHTWRDNTLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNSH
INKYQTIRKAGKVHYPIAWVNTMVFDFKGQLKTGDITLHCWSSFPDELEEMLNPIGTIQT
NPYTENATALHIHFPEYSSHPIIFPPFDKVRQTDGRPSRDLARGGKKFYIELKEIMERDP
LSQLCENEKDLIWTLRHDCWENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDA
LELLDFNYPDQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQG
NRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELI
KLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPNVQLSGINVERCRYMD
SKMKPLWIVYNNKLLSGDTLGIIFKNGDGRSQRWRMPFYFRIVKFLFHCFLFLCRIVPYG
CLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
THDFIHVIQQGKTGYTEKFGSFRQYCEEAYLVLRKNGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8D0M7Y8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLKLQIYCGKAPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTXXXXXKEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFN
WFLHLVLGIKQGEKHSA
>A0A8C0R6C1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus dingo|TrEMBL
MEPQGREPRVVLREDHRRRRRRMKARGPAAGLPSMELIPIEFVLPTSQRSSKAPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYQRLGPDHFVLLYQKKGQWYEIYDRYQVVQTLD
CLRYWQLLHRSPGQIHVVQRRAPSAATLAFQRQLTALIGYDVTDLSNVHDNELEFTRRRL
VTPRMLEVAGRDPELYAMHPWVTSKPLPDYLRKRIPNNCVFIVIHRGTTSQTVKVSADDT
PGAILRSFFAKMAKKKALMGIPEGQSERDFVLRVCGRDEYLVGDTPLQNFQWVRQCLKNG
EEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRR
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFSIKI
KDLPRGALLNLQVYCSKAPTLSAKASADAPGAGSEARGKAQLLYYVNLLLIDHRFLLRRG
EYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDP
EGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKW
GQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLH
YLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLE
AYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLN
LPESFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDL
RQDMLILQILRIMESIWETESLDLYLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGN
TGAFKDEVLNHWLKEKCAIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETG
NLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQVIGLLLVD
VCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQ
IEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A8D1EM33|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MCFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDYPLIQFQHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGL
FHGTELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKST
KTINPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMG
TVQTNPYTENATALHIKFPENKKQPYYYPPFDKSRGGKKFLAVLKEILDRDPLSQLCENE
MDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNY
PDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFL
FWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLKTLNSLIKLNAMKLN
RAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKV
FGEDSIGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVV
STSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYV
LGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTG
NTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSE
EEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6P8SDB6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MELETYEQPVVLREENKRRRRRMRPHSAAHNLSSMELISIEFFLPTFSKLTKTQDTLVLE
IAGNCTVEQMKAQVWMRAIETNLNSDFYHKLTPDHFLLHYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKSVGKIHIVEKQKMTDEVVEFQKQLNYLIGYDVTDVSNVHDDELEFTRRRL
VTPRVIELASRDPRLYSMDPWITSKPLPEYLFKKIASSNIFIVIHRGTTSQTIKVSIDDT
PNMILQTFFTKIAKKKSLLDIPEDHSELDFVLRVCGRDEYIIGDTPIRDFHWIRECHKNG
EEIHLVLDIPPDPALDEVQKEEWPLVDDCTGVTGYHEQLTIEGKDHEKVFTISLWDCNRK
FRVKVIGIDIPVLPRNTELMVFVEANIQHGQQLLAQKRTTCKPFTEEVLWNTWLDFDIKI
KDLPKGALLNLQIYCGKSPSLTTKTNVQPHDTLSSDSKCKNQLLYYVNLLLIDHRFLLRQ
GDYVLHMWKIPGKGEEQGSINADKLTSATNPDKETSMAISIVLDRYCHPIALPKHRTVSD
LEADRTRTEMPNQLRKQLEEIIATDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLASVK
WGHQETVAKTYQLLAKKEAWDRSSLDVGLTMQLLDCNFPDENVRAMAVQKLESLQDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRFAVLL
EAYLRGCGKAKLHDFMKQVQVTEMLHKVTMEIKSISAEKYDITSQVITQLRQKLDKMQNS
KFPESFRVPYDPGLRAGTLVILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDAT
TIAKIQQSTVGNTGAFKDEVLNQWLKEKCPVEEKFLASVERFVYSCAGYCVATYVLGIGD
RHNDNIMITESGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSQHF
HKFEDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGRSEDDAKR
HFLDQIEICRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8D0PPH8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
LCFLCRTSGVDCPMEFWTKEENQSVDVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQY
EPLFHMLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINS
QISLLIGKGLHEFDSLHDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSA
RSWGPGTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQ
PEDYTLQVNGKHEYLYGSYPLCQFQVRARGLPVTAGVVGSTELYRKPAKPPPTPPAMTTG
LVTGASLLRIPLLQWPCFSVHLHTQPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQA
GLFHGNETLCKTVSSSEVSVCSDPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKAR
STKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRSNPNT
ESAAALVIFLPEVAPHPVYYPSLDKVSEEPLDLPKCPGPTLPRNLEILERRGSGELYEHE
KDLVWKMRHEVQEHFPEALARLLLVTKWNRHEDVAQMLYLLCSWPELPVLSALELLDFSF
PDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFL
FWHLRYSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKT
TKPQTKELMHLCMRQETYLEALSHLQSPLDPSLAEQCTFMDSKMKPLWVMYSNEEAGSDG
SVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSD
TIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIG
DRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEK
FERFRGYCERAYAILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEAL
KHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>I3LMG0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQL
PMDCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVR
TGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKE
EHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEF
DWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTR
DPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQ
AMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKA
LTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTD
ILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKR
PLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYG
CLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLF
TRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLT
QDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFD
DIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A0S7K3I0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poeciliopsis prolifica|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLINIKQQLFIEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIMSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLENFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCENVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVSLFDYMDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
RFSQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSATDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCLNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVS
>A0A7L0HCA9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Arenaria interpres|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAMEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQALSAKTNVQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A091HYL1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calypte anna|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPESMLLE
IAGNCTVEQMKAQIWLRAVEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHDRVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEVNIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHDSANSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSASAEKYDVTSQVIVQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>G3R9L0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gorilla gorilla gorilla|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVRPPRPSPCFPGPQPSSVSLWSLEQPFRIELIQGSKVNAD
ERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYA
VIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPT
GTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKLPGGMLLASREWRPELLWMRLHAEDS
TPSRMIGVAMPGLGVLPGLVQAPGDAECSCLLQILELGRHSECVHVTEEEQLQLREILER
RGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVL
SALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRA
LANRKIGHFLFWHLRYSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEENGDGEGLKLTLLLPLAGGTDLRQDMLTLQMIQLMDVLWKQEGLDLRMTP
YGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAI
EEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPF
ILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCS
KDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A091UEB7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phoenicopterus ruber ruber|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELIAIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVIQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVV
>A0A7K6DUK9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Origma solitaria|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAVWMEYNFPLQLEPMAKGPGT
GSLHIPTKNIFVNVRFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQRPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKVA
SKPPPLPKKKPSYSSLWALEQPFHIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKQQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C4F7A0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MDGKQIQVSDEEPRVLREENRRRRRKKAITSSSSSSMDQIAVEFVLPTTARGGNSPDTLQ
LEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRLSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQMVPRPQPSDESLQYQRYLNNLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVGNGNILVVIHIGTASQTIKVSID
DPPAQVLASFFTKTANKRALLGIPENMCEEDFVMRVCGREEYLYGDKPLQNFNWIRQCLK
NGEEIHLVLESPPDPELDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKSFNEEVLWNCWLEFNI
KIKDLPKGARLNLQSKAHVCLSVHLSGKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKM
PEKSEESSSSINADKLTSATNPDKASTMAIAILLDKYCYPVVLPKSRDVGRDIGAGGEEA
EGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVR
WGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLGDDDVL
RYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLL
EAYLRGCGEDMLQDFRKQVEMTEALQKVTRDIKAMSADKYDVTAQVVFQLRQKLEALQLS
GLPKSFRVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDD
LRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVG
STGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITES
GNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICRE
KGWMVQINWFVHLVLGIKQGVEKRST
>A0A3B3QQ96|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Paramormyrops kingsleyae|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMIVALECLREATLITIKHELFKEARKYPLHQ
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDLEVQDFRRNILNVCKDAVDLRDANGPHSRALYVYPPNVESSSELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQCKYILKVCGCDEYLLEKYPLSEYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
TFTMPSYARRISTATPYMNGEASCKTLWSISSTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLQYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVAGSNPNKETPCLELEFDFF
NCPVKFPDMATVEEHANCTISRELGLNYCQSGLSNRLVRDNALTDNDTEQLCQVCNRDPL
SEITEQEKDFLWRHRYYCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDLAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8C4F411|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
NRVSDEEPRVLREENRRRRRKKAITSSSSSSMDQIAVEFVLPTTARGGNSPDTLQLEVAG
NWTVEQVKAQVWLKAVTLNLCPDFYQRLSPDHCILLYQKKGNVCEIYDKHQVFQTLDCIR
YWRALKKDVGRIQMVPRPQPSDESLQYQRYLNNLIGYDVTDVSNVHDDELEFTRRKLLTP
RRIELSDRDPKLYSMDPWVTRKPLPEHLLSILCCYRLYRIKSWVGNGNILVVIHIGTASQ
TIKVSIDDPPVLASFFTKTANKRALLGIPENMCEEDFVMRVCGRYEYLYGDKPLQNFNWI
RQCLKNGEEIHLVLESPPDPELDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTIS
MWDCNRKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKSFNEEVLWNCW
LEFNIKIKDLPKGARLNLQSKAHVCLSVHLSGKTKSRLLYYVNLLLIDHRSLLRQGEFIL
HMWKMPEKSEESSSSINADKLTSATNPDKASTMAIAILLDKYCYPVVLPKSRDVGRDIGA
GGEEAEGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKL
LGSVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLG
DDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQR
YAVLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTRDIKAMSADKYDVTAQVVFQLRQKLE
ALQLSGLPKSFRVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIF
KDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQ
QSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNI
MITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDV
CVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQI
EICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A667WZS3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MPPGKYGMQAEWEKEGDHKIMMDFLLPTGIFLKFPVSRNETIKNIKKMVWRNAATEPLFS
ALGDSDAYVFTCINQTAEREELEDESRRISDVLPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHDFEAQKNHEVNEFRSKMRSFCEEKALERQLLPWHQWIEYSFPCELEPCSSLPES
GNTKSKNTKKIFVNIKFEASDESFMLQQDPHDFPVSLMKNALKKKATVFRLVRQEPEDYT
LQVNGRWDFIYGKHPLCQFKYIFSCLRNSQNPHLIMVHSSTINKYQEEQGTMCSQVSKSG
SLSRPPPLPLKKNTSSLWSINEPFYIHLVQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SSEVAVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIR
PHPLYYPPHDKIGDMEKNGDMSVATKEEMLSLLRNWPDLPALHALELLDYSFPDPTVRAF
TIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNKRIGHFLFWHLRSEM
HVSSVSLRFGLILEAYCRGNIYHIKVLSKQNEALGKMRALSDFVKTGSQKMTAEDLKLCI
RQESYLEALSDLLSPLNPSIILSEICADKCRFMDSKMKPLWLMYKNQWVQGDMVGIIFKN
GDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRN
NSNSAATAAFNKDALLNWLKSKNPEDKIDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIM
IRETGQLFHIDFGHILGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECC
ERAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIHKCLHLDWPCSRELTSNGRHPKTIM
>A0A667WKW3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MPPGKYGMQAEWEKEGDHKIMMDFLLPTGIFLKFPVSRNETIKNIKKMVWRNAATEPLFS
ALGDSDAYVFTCINQTAEREELEDESRRISDVLPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHDFEAQKNHEVNEFRSKMRSFCEEKALERQLLPWHQWIEYSFPCELEPCSSLPES
GNTKSKNTKKIFVNIKFEASDESFMLQQDPHDFPVSLMKNALKKKATVFRLVRQEPEDYT
LQVNGRWDFIYGKHPLCQFKYIFSCLRNSQNPHLIMVHSSTINKYQEEQGTMCSQVSKSG
SLSRPPPLPLKKQNTSSLWSINEPFYIHLVQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVAVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPPHDKVLNPKHLYLSNGDMSVATKEEYMKLKEIMDNKNYTEFFEDEKELLWKL
RAEVRDRYPESLSKLLLITKWNKREDVAQMLSLLRNWPDLPALHALELLDYSFPDPTVRA
FTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNKRIGHFLFWHLRSE
MHVSSVSLRFGLILEAYCRGNIYHIKVLSKQNEALGKMRALSDFVKTGSQKMTAEDLKLC
IRQESYLEALSDLLSPLNPSIILSEICADKCRFMDSKMKPLWLMYKNQWVQGDMVGIIFK
NGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQR
NNSNSAATAAFNKDALLNWLKSKNPEDKIDQAIEEFTLSCAGYCVATYVLGIGDRHNDNI
MIRETGQLFHIDFGHILGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREC
CERAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKF
TEALRESWKTKVNWMMHSLAKDNRP
>A0A663LSD0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Athene cunicularia|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVNFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYTLQVNGKC
EYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCISSPPRMAAKPPPLP
KKKHVSLANRSSPCGFMVFSYFSFPQLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQR
LDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVSKDCPIAWVNVMLFDYKDQ
LKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVASHPVYYPSFEQT
APSLSAESDNMLCAMGIFHLEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLII
TKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQYL
LQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYC
RGSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHVCMKQETYLEALSHLQ
SPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQM
IQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKD
ALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFG
HFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLL
FLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNW
LAHNVSKDNRQ
>A0A6J1VGH1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Notechis scutatus|TrEMBL
MPGMPPGMYCPSEFWSKESNYTIHVDFLLPTGIYLPLPVSCHASLAAIKKVVWHQAQYEP
FFQMLSAPDSYVFTCINQAAELQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLLNSQI
SLLIGKGLHEFDSLADPEVNDFRVQMRDYCEQRAAQRQQLSWKDWMEYSFPVQLEPALSG
LGRRPSLPMPGKTIFVNVKFQSGGESFTFQISLKEFPITLMSYAVKKQATIFRHQRVSPA
DEYTLQVNGKYEYIYGEYPLYQFQYIRECLHRRFVPHLIMVHRSSLLTLREEQSNGLGHP
PKTALKLSPGPKQKLTCVSLWSLDQPYCIELLHCSKVNADEGMKLVVQAGLYHGHEMLCK
MMTSTEANVCSEPTWDQTLKFDIHVCDLPRMARLCLVLYSVVEKAKKARSTKKKSKKADC
PLAWVNVMLFDYQDQLKAGECVLPMWSAFPDEKGELLNPTGTIQTNPNAESAATLFIRFP
GISLYPIYYPSMRQILEKGQNGHCACGTGEDPEEKQQLKEILERRSCIELYEHEKDLVWK
MRYQIRDQYPGALAKLLMVTKWNKHEDVAQMIFLLQSWPELPVLNALELLDFNFPDPHVS
RFTVNSLKKLTDAELFQYLLQLVQVLKYQSYLDCELTKFLLGRALSNRKVGHFLFWHLRS
EMHFPSLALRFGLILEAYCRGNADHIKALMKQSEALNKLKALNDLIKVSAQKNTKPQTKE
FMHTCMRQETYLEALSHLQSPLDPRIFLARVSVELCTVMDSKMKPLWIMFNNGEAGGPST
GLIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKMGLIEVVMNSDTI
ANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDR
HSDNIMVRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFE
RFRDYCERAYMILRGHGLLFLHLFSLMKAAGLPELSCSKDIQYLKDSLALGKTDEEARKQ
FHLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6J3JMT3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sapajus apella|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLNGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRTKMCQFCEEAAACRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHFSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLDQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISISDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLHMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
YPVYYPPLEKILELGRHSECVRVTEEELQLREILERRGCGELYEHEKDLLWKLRHEVQEH
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLGALELLDFSFPDCHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMRQ
EAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSSGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A6I9PPR8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Notothenia coriiceps|TrEMBL
EAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPE
VQDFRRNILNVCKDSVEMRDASGPHSRALYVYPPNIESTQELPKHIHSKLDKGQIIVVIW
VIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQGKYILKVC
GCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYSQLPTDNFVMPSYSRRISTAT
SYMNGEASAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQMCDNVNTQR
VPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNINIFDYTHT
LVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSSLVKYPEMNAVEDH
ANWTISRELGFNYNLSGQSNRSARDHALTDSDTEQMRQLSNRDALSEITEQEKDFLWRHR
HYCMNIPEILPKILLSVKWNSRDEVAQMYCLLKEWPSTRPEQAMELLDCNYPDPMVRHFA
VRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSEM
HNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMRFL
VDQMKRPDYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMSELLFQ
NNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRSSH
TIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDLAVDLFTRSCAGYCVATFILGIGD
RHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECAKTK
EFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKSEQEA
LDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A3B4GRU3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pundamilia nyererei|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKVTADPVASLHLSQFVLHLTYLLPIVHMSR
TGQVRLSNVSLKCHPGLGDLQFLTCVSAVHPLLHHRGTSSSPDARVQRQPLLSASRLRLR
HAFLQPSDSSAVSLSRRRRRFSSSLLVGLQHSAESPAALRHVREREHQRHR
>A0A8C5J0M0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Junco hyemalis|TrEMBL
SPFNFIFLYLMPPGIYCPTEFWSKGENQSIQVDFLLPTGIYLNLSVPCNASLGTIKQVLW
KHAQYEPLFHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAK
KLINSQISLLIGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQ
LEPAAKGLSSLQIPNKNIFVNIRFHFMFQISPWEFPITLMSYAIKKQATVLRPETVQQPE
DYTLQVNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPP
KAASKPPPLPKKKERDTLSRESCPVPFPCSAQAVPRAHGAVLAVPQLVVQAGLFHGTEML
CKTVSSSEVSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKA
DCPIAWANVMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVIC
FPSVAAHPVYYPSFDPECALAVQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQ
ALAKLLIITKWNRHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGCVSCFLSVLRD
DDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPAVSLRFG
LILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCMKQETYR
EALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKNGDDLRQ
DMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVA
TAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRETGQ
LFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCERAYMI
LRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFNEALRES
WKTKVNWLAHNVSKDNRQ
>G1TVC1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryctolagus cuniculus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGIYLNFPVSRNANLSTIKQAQYEPLFHMLSDP
EAYVFTCVSQTAEPQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLLIGKGL
HEFDSLRDPEVNDFRTKMRQFCEEAAVRRQQLGWEAWLQYSFPLQLEPSARSWGAGALHA
PNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLAEQPEDYTLQVNG
RHEYLYGSYALCQFQYIRSCLHSGLTPHLTMVHSSSILAMRDEQSSPAPQVQKPRTKPPP
VPMKKPSSVSLWSLEQPFCIELVQGSRVNADERMKLVVQAGFFHGNETLCKTVSSAEVSV
SSEPVWKQRLEFDISICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAWANLML
FDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRGNPNTESAAALVICLPEVAPHPVYY
PPLEKILELGRHGERAPTSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQERFPEA
LARLLLVTKWNKHEDVAQMLHLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTD
EELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSVALRFG
LIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMRQEAYL
EALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIVYSNEEAGSEGSVGIIFKNGDDLR
QDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMA
ATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESG
QLFHVDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYT
ILRRHGLLFLHLFALMRAAGLPELSCPKDIQYLKDSLALGKTEEEALKHFRVKFNEALRE
SWKTKVNWLAHNVSKDNRQ
>A0A3Q2DCE0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinodon variegatus|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLINIKQQLFIEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIMSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLENFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCENVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVSLFDYMDILVCGKMALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
RFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSATDAEQLRSLCSKDP
LYELSEQEKDFLWRHRHYCLNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDRVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNHGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLMLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A811Y924|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nyctereutes procyonoides|TrEMBL
MCFNIIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNDFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPNDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNFPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKNI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSIQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNKAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7L2I8R1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Semnornis frantzii|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEIILLE
IAGNYTVEQMKTQVWMRAIEMSQSTDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKIANNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSEMDFVLRICGRDEYITGETRIKDFQWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVVWNIWLEFDIKI
KDLPKGALLNLQMYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNILLIDHRFLLRT
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPVALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIITTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLR
>A0A452VI70|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus maritimus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRVKKLVNSQISLLIGKGLHEFDSLHDPEVNAFRT
KMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGAGTLRVPNRALLVNVKFEGSEE
SFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYTLQVNGRQEYLYGGYPLCQFQV
SARSGRGPPSSLSLWSLEQPFCVELIQGSKVNADERMKVEGSWGRGMFSAQTRWLWSRGV
PRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGECCLYMWPS
VPGPPRRKGEANPNTESAAALVICLPEVAPYPVYYPTLDKVKAVGLKTTVLTLLPPRPSP
ELPRAGVWSPHTFGDFLNSRTLLDDELFRYLLQLVQVLKYESYLDCELAKFLLARALANR
KIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKV
SSQKTTKPQTKELMHVCMRQETYLEALSNVQSPLDPSTLLAELVLFLPRRCPDLRQDMLT
LQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAF
NKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHI
DFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRH
GLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTK
VNWLAHNVSKDNRQ
>A0A8C8A2K9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias sinensis|TrEMBL
MHPGIYGMLEEWEDGDQEINMDFLLPTGIFLKFPVSRNDTIKHIKEMVWRNARSEALFSG
LGDPDGYVFTCINQTAEREELEEEFRRIRDVKPFMCVLRLVAREGNRQEKLTNTQITQLI
GKGLHEFESQKNHEVNEFRTKMRTFCEEKALERQYLPWQRWLEYSFPCDLEPCRTPSGFG
SVKLKSSKIFINVKFEASDESFMLQQDCQDLPVALMKSALKKKATVFRSLRQEPEDYILQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPQLTMVHHSTVSRFQEEQSRMCNQMFKSRSL
SRPPPLPLKRQNTSSLWSINEPFYIQLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTS
LDVTVCSEPLWDQRLEFDINVCDLPRMSRLCFALYAVIEKTKKPKSTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSMWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRP
HPLYYPSLEKIIDFEKNGDVACTHKEEHLKLKEIMDNKHYTEFFEDEKDLLWKLRTEIRE
HYPENLSKLLLVTKWNKREDVVQMVSLLKKWPDLPAIHALELLDYSFPDPAVRSFTVRCL
RKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASV
SLRFGLILEAYCRGNIHHIKILNKQNEALAKMRALSDFVKSGSQKMTVEDLKLCIRQETY
MEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNPSTPGDMVGIIFKNGDDLR
QDMLTLQMIQLMENMWKKEGLDLSDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMI
RETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCE
QAYKILCRNGMLFVNLFAMMKAAGLPELTCFKDIQYLKDSLALGKSEDEALKNFKVKFNE
ALRESWKTKVNWMMHSLAKDNRA
>A0A3Q2P3R0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fundulus heteroclitus|TrEMBL
MDRQQFQVSDEERDVAREESRRRRRKKAITSSSSASMDQVNVEFVLPTAARGGSGPDSLL
LEVPGNWTVEQVKAQVWMKAVSLSLCPDFYQRFSPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLAPRPQQSEESQQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDSKLYSMDPWVTWKPVPEHLLSKVNNGYILVVIHVSTSSQTIKVSIE
DTPSQVLGNFFAKTANKRVLLGIPENMSEEDFVLRVCGREEYLYGERALQSFNWIRQSLK
SGEEIHLVLETPPDPELDHVQREDWAQVDDCTGVTGTHEQLTIAEKDHERVFTISMWDCN
RKFRVKVLGIDIPTLPKLPEFTVFIEASIFHGQQLLAQVICGKQPQTANSKGGSYHENTA
VTYSLEAKTKNRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEESSSSINADKLTSAT
NPDKASSMAIAILLDKYCYPVVLPKSREVGRDCVVGSEEGDAGERGQREMPNHLKKQFEA
IVSTDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRWGKQEDVLATHRLLERSYAW
DTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSAL
VRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGENMLQDFRKQVE
MTEALQKVTREMKAMSADKYDVTAQVVFQLRQKLETLQSSGLPESFRVPYDPGLRAGALL
IEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWET
ESLDLCLLPYGCISTGNKIGMIEIVKDANTIANIQQSVVGSTGAFKDEILHQWLRDKCVS
EEKFQLAVEKFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMG
ISKEWVPFVLTPDFLYVMGTSGKKISPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMT
GMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQG
VEKRST
>A0A3B4Y8B0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola lalandi dorsalis|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRAILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGCPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVSGKVALGLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDAEQLRSLCSKDP
LYELSEQEKDFLWRHRHYSVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A665V8U7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHHLLQEETSYILSEAER
EEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPEVQDF
RRNILNVCKDSVELRDATGPHSRALYVYPPNVESTQELPKHIYSKLDKGQIIVVIWVIVS
PNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQGKYILKVCGCDE
YLLEKYPISHFYLTDCSSRMPNLMLMAKDSLYTQLPTDNFVMPSYSRRISTATSYMNGEA
AAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQMCDNVNTQRVPCSNPR
WNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVANKMA
LNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSSPVKYPDMNAVEDHANWTISR
ELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPLSEITEQEKDFLWRHRHYCMNIP
EILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAMELLDCNYPDPMVRHFAVRCLDKY
LTDDKLSQYLIQLVQVLKYEQYLDNPLARHFFFWHLKSEMHNKTVSQRFGLLLEAYCRAC
GMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPL
NPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQ
IIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSN
TLHQWLKDKNKGEMYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFG
HFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHA
NLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKSEQEAVDYFMKQMNDAHHGGWTTKM
DWIFHTIRQHALN
>A0A665V862|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECTKTKEFESLIPQPARAP
>A0A1S3GPF2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dipodomys ordii|TrEMBL
MMPPAMADILDIWAVDSHIASDGSIPVDFLLPTGIYVQLEVPREATISSIKQMLWKQVHH
YPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSK
IGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEEKIQSLVGLSWIDWLKQTYPPEHEPSVL
ENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMTPIKVNELAIQKRLTIHGKEDEASPSD
YVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRSLPHFILVECCKIKKMYEQEMIAIEAAVN
RHSSNLPLPLPPKKTRVVSHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLC
KTVVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTINPAKY
QTIRKAGKVHYPVAWVNTMIFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRD
PLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPRE
ALELLDFNYPDQYVREYAVSCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERAL
ANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSL
IKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKP
LWLVYSNKMFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATG
DRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSC
AGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFI
HVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A2K6D557|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca nemestrina|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDLPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPFSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDIHICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A665UJF5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MDGQQIQLSDDEPKFQREEIRRRRRKKAITSSSGTSMDQITVEFILPTVARGGNSPDSLQ
LEVAGNWTVEQVKAQLWLKAVTSNLCPDFYQRFSPDHCILLYQKKGNLYEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESLHYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVSNGHILVVIHIATASQTIKVSID
DTPAQVLASFFTKTANKRVLLGIPENMCETDYVLRVCGREEYLYGDKPLQNFNWIRQCLK
NGEEIHLVLETPPDPNQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTVSMWDCN
RKFRVKVLGIDIPSLPKVPEFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNSWLEFNI
KIKDLPKGARLNLQVVCGKQPQTPNSKVNSFQDNAGGGNYDGKTKSRLLYYVNLLLIDHR
SLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPK
SRDVSRDVPAGAEEAEGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRQEC
MRDPRAYPKLLSSVRWGKQEDVLTTHHLLERSSAWDSSGLDVGLAMQMLDCHYSDAQVRS
MAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGEAMLQDYKKQVEMTEALQKVTREMKTMSADKYDVTAQ
VVFQLRQKLETLQLSGLPESFRVPYDPGLRAGGLMIEQCKVMASKKKPLWLQFKRADPTT
LSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIV
KDATTIANIQQSVVGSTGAFKDEILYQWLRDKCISEDKFQQAVERFLFSCGGYCVATYVL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKS
SPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRVED
EAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A7K9IUY0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myiagra hebetior|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGAIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAARRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVRFQSGGESFTFQISPWEFPITLMSYAVKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
CKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVQETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>H2SZ17|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
MNILCAVRSLWLRWLAVPLAMPPAMTDLLDIWATHAPLAGHDPDQITMDFLLPTGIYIQC
DVPRVATIKEIKQLLWKEAHSFPMFSKLGEMESHMFECVNQAAVHEELEDETRRLCDIRP
FLPVLKLVTRNCGRGERLLDSKIGVLIGKGLHELSAINDQEVKDFRSKMTRISEERMQTI
ERMTCTEWLQASYSSQLDVPADTTTMDGTDRPADLKIIIHFDQSLDSASLKMASTCTPRD
LITQAVRKWLTTHGPEEDALRGQYVLRVSHCLEFLCGDHPLIQYKYIRTCMQAKEPPHVT
LVHNNTIKTMFERDICAIRAALTPKSCSLPLPLPPKKRAPTQVQTCVWDVSSPFKIVLVN
ASKVNAEETAKVQVRAGLFHGTELLCKPAVSSESSGRSDHAWKDTTLEFELPVCDLPRMT
RLCFAIYAVMDKVKKQKSTKNTHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDII
LHCWSSFPDELEEMLNPIGTIQTNPYTENATALHISFPEYSSHPIIFPLFDKILEKAAEI
AGASDCASMGRGGKKFHIELKEIMERDALSQLCENEKDLIWTLRYDCRENFPQSLPKLLL
SVKWSKHEDMAQLQALLQIWPRLCPRDALELLDFNYPDQYVREYAVNCLRDMSNDELSQY
LLQLVQVLRYEPYYDCALTHFLLERAQSSRKIGHFLFWHLRSEIHMPAVSVQFSLILEAY
CRGSIPHIEVLKKQVEALNKLKAVNELIKLGTLKNARSKTKEAMLTKEAMMTCLRQTGFS
ETLSDLHSPLNPNILLSGINVEKCRYMDSKMKPLWIVYNNKLLVGDMLGIIFKNGDDLRQ
DMLTLQILRLMDRLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNMAA
AAAFNKDALLNWLKERNSGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSNGQ
LFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGQAEKFGSFRQYCEKAYLI
LRKNGNFFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSDDEALKQFRQKFDEALRES
WTTKVNWMAHNVAKDNRS
>A0A674NZ59|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
MPPAMTDLLDIWATHAPLAGHDPDQITMDFLLPTGIYIQCDVPRVATIKEIKQLLWKEAH
SFPMFSKLGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRGERLLD
SKIGVLIGKGLHELSAINDQEVKDFRSKMTRISEERMQTIERMTCTEWLQASYSSQLDVP
ADTTTMDGTDRPADLKIIIHFDQSLVRAYFSYQGSALDLITQAVRKWLTTHGPEEDALRG
QYVLRVSHCLEFLCGDHPLIQYKYIRTCMQAKEPPHVTLVHNNTIKTMFERDICAIRAAL
TPKSCSLPLPLPPKKRTCVWDVSSPFKIVLVNASKVNAEETAKVNVRAGLFHGTELLCKP
AVSSESSGRSDHAWKDTTLEFELPVCDLPRMTRLCFAIYAVMDKVKKQKSTKNTHINKYQ
TIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTE
NATALHISFPEYSSHPIIFPLFDKILEKAAEIAGASDCASMGRGGKKFHIELKEIMERDA
LSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPRLCPRDA
LELLDFNYPDQYVREYAVNFPSNRVFLSPFISNDELSQYLLQLVQVLRYEPYYDCALTHF
LLERAQSSRKIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALNKL
KAVNELIKLGTLKNARSKTKEAMLTKEAMMTCLRQTGFSETLSDLHSPLNPNILLSGINV
EKCRYMDSKMKPLWIVYNNKLLVGDMLGIIFKNGDDLRQDMLTLQILRLMDRLWKEANLD
LRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNMAAAAAFNKDALLNWLKERNSGDA
LERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSNGQLFHIDFGHILGNFKSKFGIKR
ERVPFILTHDFIHVIQQGKTGQAEKFGSFRQYCEKAYLILRKNGNFFITLFALMLTAGLP
ELTSVKDIQYLKDSLALGKSDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C3QIK7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyanoderma ruficeps|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEETP
CLELEFDWFSNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQL
RAICTRDPLSEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWP
SIKPEQAMELLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVR
FLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEK
LINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRI
MSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDL
RMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYD
AAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRER
VPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMP
ELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C5CRP2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MPPGNYGMEEEWEAEGNADIMVDFLLPTGIFLEFPVSRNDTIADIKKLVWRRASSEPLFN
ALGDPASYVFVCISSAAERLELEAEHRRLADVRPFACFLQLVAREGDRAEKLANAQISLL
IGKGINEFEAQKNHEVSEFRARLRAFCEEKALQQQALPWFQWMECNFPCDLEPCRALPSR
GGGAKAPKKIFINIQFEGSDESFMLQQDPQEPPLALIRSALKKKATVFRWVRQEAEDYTL
RVNGRWDFLYGDHPMCQFKYIFSCLRDGQNPQLTMVYHSTIRAYQEDQGSAWRQGSKSST
SASKPPPLPLKKVGRRGGLCLSLEPLCIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKL
VTSSEVAVGSDPVWNQRLEFDINVADLPRMSRLCIALYAVVEKAKKPRGTKKKSKRADCP
IAWVNTMVFDYKDQLKTGEFLLSMWPSIPDDKSELLNPMGTVEKNTNVDSAAALLIHFPS
VRPQPLYYPPHDKVTGGGGSRHVRLKEIMDNKNHTEFFEDEKELLWKLRGAVQSLYPESL
SKLLVITKWNKREDVAQMVGLLRAWPELSGLHALELLDYSFPDPSVRAFTVKCLKKLGDR
ELMQYLIQLVQVLKYESYLDCDLTSFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGL
ILEAYCRGNIHHIRSLTKQNEALGKLKALSDIVKSGSQKMSADDLKLCIKQDSYMEALSD
LLSPLNPSIILSEICVEKCKYMDSKMKPLWLMYKNQWVPGDLMGIIFKNGDDLRQDMLTL
QMIQLMENLWKKEGLDLRHKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQL
FHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRDYCERAYKIL
CRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKTEEEALKSFKVKFNEALRESW
KTKVNWMMHSLAKDKRP
>A0A8C2C399|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSPELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKVFRLSLSQNLYADYVALRISVCLFLDNFT
MPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGIYHG
GEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLA
WGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSSP
VKFPDMATIEDHANWIISREMGYNYCQSGQVSQFRFDQNTEKDFLWRHRQYCVNIPEILP
KILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDD
KLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGL
LLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMD
ALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDD
LRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGL
KGALQFNSSTLHQWLKDKNRGEMYDMAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDD
GQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCY
KAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMND
AHHGGWTTKMDWIFHTIRHHAQN
>A0A8C1QBW6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGLCHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVA
QSGKSRSVKKILVNVKFEGSEVSEFMLIYHSFMLSGNSFLWYNAIKKSTVFRAAKQEKPE
DYTLQVNGRWEFIYGEYPLCQFKVSLKVTTSSRLHSYSTTLSDSRTHVFLNLILLFSYFF
FCIYILFYSLQSLSFSQLVVQAGLFHGSELLCKVVISNEVSVCSEPVWDQKLVFDIGVSD
LPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFSLSTWPS
VPDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKVRGKKSNVLIVDNKNYTE
FFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALEL
LDYSFPDPHVRSFTIRCLRNLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLKRALANKK
IGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSG
SQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCTDKCKFMDSKMKPLWLM
YKNKYDHVGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIE
VVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVAT
YVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGR
TNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGK
SEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A669QZE2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phasianus colchicus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVNFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYTLQVNGKY
EYLYGNYPLYQFQVSLLSCFDKRKSPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQA
GLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKAR
STKKKSKKAVSKDCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCN
PNTESAAALLICFPNVASHPVYYPSFETEICSARDSSLMHQKLQLKEILERRSHTELYEH
EKDLVWKMRHDIRDQYPQALAKLLTITKWNKHEDVAQMISLLQSWPELPVLNALELLDFS
FPDRYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHF
LFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKA
TKPQAKEMMHVCMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNE
ETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEV
VMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATY
VLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKT
NNSEKFERFRGYCEKAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKT
DEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C2DJS4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGLCHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVA
QSGKSRSVKKILVNVKFEGSEETFVLQQDPQDLPMLLKRNALRKKSTVFRAAKQEKPEDY
TLQVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQMSRT
RAPSKPPPLPLKRVRMHFYTGTRSVINRGTTCHVSLVASLQSLSFSQLVVQAGLFHGSEL
LCKVVTSNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRA
DCPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPDLLNPMGTVEKNPNIDSTAGLLIRFPNI
RPHPLYYPPIEKHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITKW
NKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHVRSFTIRCLRNLRDDELFQYLLQL
VQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGS
IFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPL
NPSIVLCELCTDKCKFMDSKMKPLWLMYKNKYDHVGIIFKNGDDLRQDMLTLQMIQLMDV
LWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWL
KSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNF
KSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFA
LMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFA
KDNR
>A0A8C1I4L5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVI
SNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNDLGMNGEKTTKEEMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIR
CLRKLSDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVP
SVSLRFGLILEAYCRGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVC
IKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGD
DLRQDMLTLQMIQLMDVLWKTEGLDLRICRTWSTFSEEQCSVQLFRTNKELMNNYHKTER
QSWIIQVTTHSIKNQGFPNF
>A0A8C1NH68|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVI
SNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNDLGMNGEKTTKEEHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQRY
PESLPKLLLITKWNKHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRK
LSDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSL
RFGLILEAYCRGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQD
TYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQ
DMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAA
TAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMISETGQ
LFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKI
LCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRES
WKTKVNWMMHTFAKDNR
>A0A8C2AB27|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGLCHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVA
QSGKSRSVKKILVNVKFEGSEETFVLQQDPQDLPMLLKRNALRKKSTVFRAAKQEKPEDY
TLQVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQMSRT
RAPSKPPPLPLKRVRMHFYTGTRSVINRGTTCHLSLVASLQSLSFSQLVVQAGLFHGSEL
LCKVVTSNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRA
DCPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPGDLLNPMGTVEKNPNIDSTAGLLIRFPN
IRPHPLYYPPIEKHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITK
WNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHVRSFTIRCLRNLRDDELFQYLLQ
LVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCRG
SIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSP
LNPSIVLCELCTDKCKFMDSKMKPLWLMYKNKYDHVGIIFKNGDDLRQDMLTLQMIQLMD
VLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNW
LKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGN
FKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLF
ALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTF
AKDNR
>A0A8C6PLR3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius furzeri|TrEMBL
MPPGKYGMQEEWEKEGDQNILMDFLLPTGIFLKFPVPRNDTIKNIKKVCALYCGLGDPEG
YVFTCINDTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNSHISSLIGKGLHE
FEAQKNHEVDEFRSKMRTFCEEKALERHNLPWQQWMEYSFPCDLEPCCSPPVHGGTKSKH
TKKLFINVKFEESFMLQQDPLDIPVALMKSALKKRATVFRSVRQEPEDYTLQVSGRWEFI
YGNHPLRQFKVMNANVMGRKKDQNKNKIPISSSFCSFLQQNTSSLWSINEPFYIHLLQGS
RVNADEGMKVGVAGLFHGSELLCKVVTSSEVTVCSEPLWDQKLDFDINVSDLPRMSRLCF
ALYAVIEKTKKPRGTKKKNKRLPSRFQDCPIAWVNTMVFDYKDQLKTGEFILSTWPSVPD
DKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPLDKVIPPENLLISMIVMERN
GDAVFRMRLKEIMDNKNSTEFFEDEKELLWKLRTEVRDCYPESLSKLLLITKWSKREDVV
QMVSLLRNWPDLPAIQALELLDYSFPDPAVRSFTIRCLRKLSDNELLQYLIQLVQVLKYE
SYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIKLL
TKQNEALGKMKALSDIVKSGCQKMTVEDLKLCIRQESYMEALSNLMSPLNPSIILVELCA
DKCRFMDSKMKPLWMMYKNPSEHADMVGIIFKNGDDLRQDMLTLQMIHLMEDLWKKEGLD
LRMIPYGCLSTGNKMGLIEVVKHSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDK
LDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINR
ERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEWAYKILCKNGTLFVNLFAMMKAAGLP
ELTSSKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A383Z4K1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balaenoptera acutorostrata scammoni|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWPQYEPLLPML
SDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIG
KGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGPGT
LRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYALQ
VNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRAK
PPPIPLKKPASVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSE
VSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWAN
LMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAPHP
VYYPALDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQEHF
PEALARLLLVTKWNKHEDVAQMLHLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRK
LTDDELFQYLLQLVQVLKYESYLDCELTKFLMDRALANRKIGHFLFWHLRSEMHVPSVAL
RFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQE
TYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKNGD
DLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLNKS
NMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIR
ENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCER
AYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEA
LRESWKTKVNWLAHNVSKDNRQ
>A0A485P1R2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lynx pardinus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7L3AYH5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Syrrhaptes paradoxus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLFQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAAEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRHN
IRDQFPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L2VDF9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Brachypteracias leptosomus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGSIKQVVWKHAQYEPLFH
MLSDPESYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVHDFRTKMCQFCEERAAKRQQLSWTAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKKPNYSSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAAEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGKGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A553ML47|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Danionella translucida|TrEMBL
MEQQASDDEPAVVHREENKRRRRKMKAFTSSSAISMEHITVDFQLPTINKNSKIQDTLQL
IVTGNWTVEQVKVQLWHRAVTTKLNPEFYQKYSPDHCILLYQKKGNWYEIYDKQQVFQTL
DCFRYWKALRKEVGKIHLVVRPQPTEDSFQYQQFLNYLIGYDVTDVNNVHDDELEFTRRK
LLTPRKIELSDRDPKLYSMDPWMTTKPLPEYLLSKISSNHILVVIHKETTSQTIKVSLDD
TPVQVLQSFFAKIINKRALLGISEDLDESDFVLRVCGREEYLYGNYPVKDFHWIRQCLKN
GEEIHFVLEQPLNPDQDVVQKEDWSQVDDCTGVSGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTPKPFTEEVIWNTWLEFGIK
IKDLPKGARLSLQVSCGKAQTPNSKESDCKNKTRLLYYVNLLLIDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKNTSMAVAILLDKYCYPVALPKSKDSPDSEMEGERG
QREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECLRDPKAYPKFLSSVKWGNQEA
VAIIHRCLERSSVWDRSVLDVGLVLQLLDCHFSDENVRTIAVRKLETLGDDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSVHYQQRYAVILEAFLRG
CGDAMLQDFRKQVEITEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQAAGLPDNF
KVPYDPGLRAGALVVDQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGNFF
>A0A668VX85|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MDRQQIQVSDEESQVPREESRRRRRKKAITSSCSNSMDQITVEFVLPTAARGGSGSDTLQ
LDVAGNWTVEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTCKPLPEHLLSKINNGHILVVIHIGTASQTIKVSID
DTPTLVLVSFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLK
NGEEIHLVLEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKQPQIPNSKGSSYQESTAGSSSLDGKTKSRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLP
KSRDVGRDWAVGGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHE
CMRVPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVR
SMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSKHYQQRYAVLLEAYLRGCGENMLQDFRKQVDMTEALQKVTREIKTMSADKYDVTP
QVVFQLRQKLENLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADST
TLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKK
SSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSE
DEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A2K5HAU3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Colobus angolensis palliatus|TrEMBL
MELENYEQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETVLLH
VAGHGNVEQMKAQVWLRAMETSVASDFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGKTPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFTIKI
KDLPKGALLNLQIYCGKAPAVSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDTCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A668UK36|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
GQRGMKCTTRGWQAGESYSDCLTQKQCCEVMSHIYSSFLKMLSALFYETLLWKQAQSFPL
FPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLDSKIG
VLIGKGLHELDALNDQEVKDFRSKMFRISEERMQQIQMMTFSEWVQACYSPQLEPAAVTA
ITAGVNDFPFLQDSASLKVSLSCTPNELMEQALRKWLTTHGSEDAVWRGQYILRVSQCLE
FLGGDHPLIQYKVISHKLAKIFCLSLHLWPLSGWLVIVKFNPSCITQVQVRAGLFHGTEL
LCKPAVSNESSGRSEHTWKDNTLEFEISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNPHI
NKYQTIPWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATALH
IHFPEYSSHPIVFPPFDKVTQHSIVIFSQINKMIPICPFKTYQLGRGVKKFYMELKEIME
RDPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSP
RDALELLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLER
AQRNRQIGHFLFWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQVEALSKLKSVN
ELIKLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDINVEKCR
YMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIV
PYGCLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRA
IEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVP
FILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTS
VKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7L3ZLX5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Circaetus pectoralis|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNIKFQSGGESFTFQISPKEFPVTLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAL
HPVYYPSFEQLLELGRNGEQPRAGPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3P9CCS3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Maylandia zebra|TrEMBL
MDRQQIQVSDEECQVPREESRRRRRKKAITSSCSTSMDQISVEFVLPTAARGGSGPDTLQ
LDVAGNWTVEQVKAQVWMKAVTSNLCPEFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTRKPLPEHLLSKINNGHILVVIHIGTASQTIKVSID
DTPTLVLASFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLK
NGEEIHLVLEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNI
KIKDLPKGACLNLQVICGKQPQIPNSKGSSYQESTAGSSCLDGKTKSRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLP
KSRDVGRDWAVGGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHE
CMRDPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVR
SMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSKHYQQRYAVLLEAYLRGCGENMLQDFRKQVDMTEALQKVTREIKTMSADKYDVTP
QVVFQLRQKLENLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADST
TLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKK
SSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSE
DEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>L9L0U3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tupaia chinensis|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGIYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSAPSLRA
STLRGPNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLLEQPEDYT
LQVNGRHEYLYGSYPLCQFQAVVNREAPGSSCPGSGWGGRASGSLCTLSQYICSCLHSGQ
TPHLTMVHSSSILAMRDEQSNPAPQVQKPRTKPPPVPVKKLSSVSLWSLEQPFCIELIQG
SKVNADERMKLVVQAGLFHGNEMLCKTVSSCEVSVCSEPVWKQRLEFDINICDLPRMARL
CFALYAVIEKTRKARATKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKG
ELLNPTGTVRSNPNTESAAALVICLPEVAPHPVYYPALEKILELGRPGERGRFTEEEQLQ
LREILERRGSGELYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCS
WPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELT
KFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALS
KLKALNDFVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCT
FMDSKMKPLWIMYSNEEAGSDGSVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRM
TPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDTLDR
AIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERV
PFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELS
CSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3P8RAM2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astatotilapia calliptera|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDSEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A4W3JCA0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPAMTDPLDIWAVDSQIPADNSITVDFLLPTGIYIQLDVPREATIDQIKMLLWRQAQTY
PLYTVLGEKDSYMFQCVNQSAVHEELEDESRRLCDVRPFLPVLKLVARNCNRSERLLDSK
IGVLIGKGLHEFDALTDPEVREFRSKMRMFNEEKMLKLQGLSWMDWLKHSFPPELESTAF
NNFEDKLPKENLVVAVHPGLFLAIRKQLTIHGKENEEFNPRDFVLRVSGKQEYLFGEQPL
IQFRYIRNCVLKGSNPQLTLVDCCTIKEMCDREMSAIGVALHRKISNAPLPLPPKRRTIS
QMATNVWDINSPFKMLLIRGNKINADEAVQVRAGIFHGTELLSKSVVSTEVSGKNDLVWN
EILDFEINLCDLPRMSRLCFAVYGVMDKVKKQKSTKNASKYQTIRKAGKVHYPIAWVNTM
VFDFRAQLKSGDLDLHCWSSFPDEMEDMLNPMGTVQTNPYSENAASLHIQFQEYSKSVIY
YPAFDKILEKAAEIARSNDTLSMSGRGGKKLHIELKEIMERDPLSQLCENEMDLIWTLRY
DCRENFPQSLPKLLLSVKWSKHEDVAQLQALLQIWIKLCPRDALELLDFNYPDQYVREYA
VKCLKEMSDEELSQYLLQLVQVLKYEPYFDCALSRFLLERAQANRRIGHFLFWHLRSEMH
LPATSLQFGLILESYCRGSFTHIKELSKQMEALSKLKAINNLVKLSYLKVTRTKVKEVMN
TCLKQPVYTEALSDLQSPLNPSVILSKLNVDKCKFMDSKMKPLWILYNNKMSGGEPVGII
FKNGDDLRQDMLALQILRLMDMLWKEAGLDLRIVPYGCLATGDKSGLIEVVSASETIANI
QLTNSNVAATAAFNKDALLNWLKEKNTGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMVRETGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKPGNAEKFGRFR
QCCEEAYLILRKNGNLFITLFALMLTAGLPELSSVKDIQYLKDSLALGKSDDEALKQFRQ
KFDEALRESWTTKVNWMAHIVAKDNRS
>A0A7J6BMN4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Onychostoma macrolepis|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSADLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKIAHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDEYLLEKYPLSQYKYIRSCITLGRLPHLMLVSKDSLYSQLPSS
GFMAPSYSRRTPQPSPCPGGADPGAPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDEQQIEEHANWSISRELGYSYCLGLSSRLACDSSISQADAEQLRTLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQIYCLLKDWPLMQPESAL
ELLDCNFPDPMVREFALRCLIQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIREKNKGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKNQQDALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A674K392|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Terrapene carolina triunguis|TrEMBL
MPPGIYCPVEFWSKEENQTIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVRDPEVNDFRAKMRQFCEEKAAKRQQLSWMAWMEYNFPLQLEPLAKGPRT
GPLRVPNKNIFVNVKFESGGESFTFQVSPKEFPVMLMSYAIKKQATVFRHQTVESPEDYT
LQVKGKCEYLYGNYPLYQFQYIRSCLHHGLMPHLTMVHFSSIIAMRDEQTNCTAHTPKMV
SKPPPLPKKKLVVQAGLYHGNEMLCKMVSSAEVNVCSEPVWKQRLDFDISICDLPRMARL
CFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKG
ELLNPMGTVQSNPNTESAAALVICFPSVLLHPVYYPSFEQLLELGRNGDYTRKQQLREIL
ERRSHTELYEHEKDLVWKMRFEIRDQYPEALAKLLIITKWNKHEDVAQMISLLQSWPELP
VLNALELLDFSFPDRYVGSFTINSLKKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLD
RALANRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSNYHMKVLMKQGEALNKMKAL
NDFIKVSSQKATKPQAKEMMHVCMKQETYLEALSNLQCPLNPTVILAEVCVDHCTFMDSK
MKPLWIVFNNEEAGGRGVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
STGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALEQAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRDYCEKAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQ
YLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L0UUJ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptocoma aspasia|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIILHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRR
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKALGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISVVLDKYCHPVALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLDDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKEMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLKQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A674IVU5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Terrapene carolina triunguis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVCPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWVINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMTVTEEHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A674K5J8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Terrapene carolina triunguis|TrEMBL
ICIMGVMPPYRAGVYCGSDTSGGDVMVQPAHRWFHPAVGLSQVVWRHAQYEPLYHMLNDP
EAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIGKGL
HEFDSVRDPEVNDFRAKMRQFCEEKAAKRQQLSWMAWMEYNFPLQLEPLAKGSLMIPACC
CEESFTFQVSPKEFPVMLMSYAIKKQATVFRHQTVESPEDYTLQVKGKCEYLYGNYPLYQ
FQVSLFPPPTGELFPKRTGTFLSGRQEKDAPCYCRPCSLCRPTHESLWSLNQPFYIELVQ
GSKVNADERMKLVVQAGLYHGNEMLCKMVSSAEVNVCSEPVWKQRLDFDISICDLPRMAR
LCFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEK
GELLNPMGTVQSNPNTESAAALVICFPSVLLHPVYYPSFEQVKGRHLSADRFTNFASCGG
KGALPQLREILERRSHTELYEHEKDLVWKMRFEIRDQYPEALAKLLIITKWNKHEDVAQM
ISLLQSWPELPVLNALELLDFSFPDRYVGSFTINSLKKLTDDELFQYLLQLVQVLKYESY
LDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSNYHMKVLMK
QGEALNKMKALNDFIKVSSQKATKPQAKEMMHVCMKQETYLEALSNLQCPLNPTVILAEV
CVDHCTFMDSKMKPLWIVFNNEEAGGRGVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEG
LDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPG
EALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGI
NRERVPFILTYDFVHVIQQGKTNNSEKFERFRDYCEKAYMILRCHGLLFLHLFALMKAAG
LPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P3VIZ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Clupea harengus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVCLECLREAPLLTIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFQPLLKVIEPIGNREEKILNREIGFA
IGMPICEFELVKDSEVQDFRRSILCVCREAMEEREGGGAHSQALYVYPPNVESSPDLPPH
IFSKLDKGRLIVTIWVIVSPSNAKQKYTLKISHDSLPEQLIAEAIRKKTRSMHLSAQQLR
MCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVSRLPHLMLVSKDSLYSQLPAS
GFVAPSYSRRTPQPSPCPGGSDPSPPRTLWAFNTLLRLRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVHTQRVPCSNPRWNEWLTYDIYLTDLPRAARLCLSICSVKGRKGAKEE
HCPLAWGNVNMFDYKDTLVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVMFPDEQQIEEHANWVISRELGYNYCMGLSSRLACDSTVSPSDGEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLQAVKWNSRDEVSQMYCLLKDWPLMQPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDKAIELFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A8B7I8L7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Apteryx mantelli mantelli|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWSINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A1U7T394|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carlito syrichta|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAVRRQQLGWEAWLQYSFPLQLEPSARSWGA
GGLRLPSRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPPVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYIRSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPVKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISVCDLPRMARLCFALYAMIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
HPVYYPALEKILELGRHSGCGHVTEEELQLREILERRGSGELYEHEKDLVWKLRHEVQEH
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLGALELLDFSFPDCHVGSFAIKSLR
KLKDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLILEAYCRGSTHHMRVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMRQ
EAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSDGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A1W7REU8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Agkistrodon contortrix contortrix|TrEMBL
MPPRPSSGELWGMHLMPPKILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVELRDANAPHSRALYVCPPNIESSDLPKHI
YNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLKL
CVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMTKESLYAQLPLDT
FAMPSYSRRISTATPYMNGEASAKSLWAINSHLRIKILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLQYEMLVLDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFS
SPVKFPDMSVIEEHANWIISREQGFNYNHAGLSNRIARDNELRDNDKEQLRAICTRDPLS
EITEQEKDFLWSHRHYCVSMPEILPKLLLSVKWNSRDEVTQMYCLVKDWPQIRPEQAMEL
LDCNYPDPMVRAFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQ
RIGHFFFWHLKSEMHNKNVSQRFGLLLDSYCRACGMYLKHLSRQVEAMEKLINLTDILKQ
EKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLWL
NWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSI
GDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDPAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAY
IRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C9LD69|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pavo cristatus|TrEMBL
MKPHCTSSNLSSMELITIEFILPTSNKHTKAPEMMLLEIAGNCTVEQMKAQIWMRAIEVS
QTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLDCILYWKVLQKKVGKIYVVQKQK
PSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRLVTPRMIEVACRDPKLYAMHPWT
TSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDTPDMILHSFFTKMAKKKSLMDIP
EDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNGEEIHLVLDNPPDPSEDEVQKEE
WPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRKFRVKIIGIDIPVLPRNTDLTVF
VEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKIKDLPKGALLNLQIYCGKAQGLS
TKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRSGEYVLHMWKIPGKGEEQGSINA
DKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSDSQGDRTRAEMPNQLRKQLEEII
ATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQEIVAKTYQLLAKKEVWDQ
SFPTDCCVVSLACKRALHMLLTRLLCIFQAVKFEPYHDSALARFLLKRGLRNKRIGHFLF
WFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLHDFMKQVQVIELLHKFLFLLSLSYLKA
VSDLHVSLRFISDLEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLI
LQILRIMESIWEAESLDLCLLPYAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETVNE
DVYLMEPLPWSCTTPLSLNCREMQLGRP
>A0A093FL08|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tyto alba|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSSLSSMELISIEFILPTSNKHTKVPEMILLE
IAGNCTVEQMKAQIWMRAIEISQTTDFYRAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIFVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTVDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTHESPNSDSKCKTQLLYYVNLLLIDHRFLLRSGEYV
LHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDSYCHPIALPKHRITSDPQGD
RTRAEMPNQLRKQLEEIIGTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQ
EIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVLHYLL
QLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYL
RGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSSNLPE
SFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQD
MLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTGA
FKDEILNQWLKERCMIEEK
>A0A4W4GUA6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
VELHSDDEPPIVLRKEDKRRRRKMKAFTSNSCMEMDHLAMEFLLPTTNKITKNPDMLQLS
VTGNWTVEQVKTQVWLRAVTTNLCPEFYQKYSPDHCILLYQKKGSWCEIYDKHQVFQTLD
CIRYWKALKKDVGKIHLVLRPQPSEESIQYQKFLNYLIGYDVTDVSNVHDDELEFTRRKL
LTPRKIELADRDPKLYSVDPWITTKPLPDYLLSKITNSHILVVIHKDTSSQTIKVSIEDT
PVQVLHSFFLKTANKRALLGLPEDVSESDFVLRVCGREEYIFGNYAIKDFHWIRQCLKSG
EEIHLVLETPPNPDQDVVPKEDWSQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRK
FRVKILGIDIPVLPRNSELIVFVEASIYHGQQLLAQERTLPKPFTEEVLWNVWLEFNIKI
RDLPKGSRLNLQVSCGKAQTQASKDSTGHDGRNKGRLLYYVNLLVVDHRSLLRQGDFILH
MWKMPEKTEDNSSVNADKLTSATNPNKTTSMAITVLLDKYCYPVALPKSRDSRESSDGEE
ERGNREMPNHLRKQFEQIVVTDPLHPLSIEDKELLWHFRQECTRLPTAYPKFLGSVKWGK
QEDVMITHRLLERSTAWERSSLDVGLAMQLLDCHFSDANVRTMAVRKLETLGDDDILRYL
LQLVQAVKFEPYHDSALARLLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAY
LRGCGEAMLQDFRKQVEITEALQKVTRDIKAVSAEKYDVSPQVVFQLRQKLESLQVSGLP
NSFKVPYDPSLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLTNDSIGIIFKDGDDLRQ
DMLILQILLIMESIWDTESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTG
AFKDEILNQWLRDRCVSEDKFQQAVERFVYSCGGYCVATYVLGIGDRHNDNIMITESGNL
FHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTTGKKSSPNFLQFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSTEDIEYIREALTVGCSEDQAQKHFLDQIEICRDKGW
TVQFNWFLHLVLGIKQGVEKRSA
>A0A6J1ZKD6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acinonyx jubatus|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINICDLPRMARLCFAIYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A250Y6R8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Castor canadensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDFNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETATKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A4X1V2C6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLDCLRYWKVLH
RSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRLVTPRMAEVA
GRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDTPGTILQSFF
TKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNGEEIHLVLDT
PPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGID
IPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALL
NLQIYCGKAPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEYVLHMWQLSG
KGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPN
QLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQQEIVAKTYQ
LLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKF
EPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAML
HDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLPQSFRVPYDP
GLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILR
IMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLSH
WLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHIL
GNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLII
LFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLH
LVLGIKQGEKHSA
>A0A8D1EJF2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MCFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDYPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKSRGGKKFLAVLKEILDRDPLSQLCENEMDL
IWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQ
YVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWH
LRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLKTLNSLIKLNAMKLNRAK
GKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGE
DSIGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTS
ETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGI
GDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTE
KFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEA
LKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A452HN79|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gopherus agassizii|TrEMBL
MPPGIYCPVEFWSKEENQTIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVRDPEVNDFRAKMRQFCEEKAVKRQQLSWMTWMEYNFPLQLEPLAKGPRT
GPLRIPNKNIFVNVKFESGGESFTFQVSPKEFPVTLMSYAIKKQATVFRHQTVESPEDYT
LQVKGKCEYLYGNYPLYQFQYIRSCLHHGLMPHLTMVHFSSIIAMRDEQTNCTAHTPKMV
SKPPPLPKKKPTHESLWSLNQPFYIELVQGSKVNADERMKLVVQAGLYHGNEMLCKMVSS
AEVNVCSEPVWKQRLDFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQSNPNTESAAALVICFPSVTP
HPVYYPSFEQLLELGRNGEYTRATPEDPEEKQQLREILERRSHTELYEHEKDLVWKMRYE
IRDQYPEALAKLLIITKWNKHEDVAQMISLLRSWPELPVLNALELLDFSFPDRYVGSFTI
NSLKKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSNYHMKVLMKQGEALNKMKALNDFIKVSSQKATKPQAKEMMHV
CMKQETYLEALSNLQCPLNPTIILAEVCVDQCTFMDSKMKPLWIVFNNEEAGGRGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVLHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTTNSEKFERFRD
YCEKAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C1NHA1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVI
SNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLWLAEHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLI
TKWNKHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLSDDELFQYL
LQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYC
RGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVV
SPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQDMLTLQMIQL
MDVLWKTEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMISETGQLFHIDF
GHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGT
LFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVN
WMMHTFAKDNR
>A0A6J0GZ21|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lepidothrix coronata|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYIIGETPVKDFHWIRQCLKNG
EEIHLVLDDPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDTKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDICVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6J1U1E6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Notechis scutatus|TrEMBL
MPPRPSSGELWGMHLMPPKILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVELRAANAPHSRALYVCPPNIESSDLPKHI
YNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLKL
CVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMTKESLYAQLPLDT
FAMPSYSRRISTATPYMNGEASAKSLWAINSHLRIKILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLQYEMLVHDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFS
SPVKFPDMSVIEEHANWIISREQGFNYNHAGLSNRIARDNELRDNDKEQLRAICTRDPLS
EITEQEKDFLWSHRHYCVSMPEILPKLLLSVKWNSRDEVAQMYCLIKDWPQIRPEQAMEL
LDCNYPDPMVRAFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQ
RIGHFFFWHLKSEMHNKNVSQRFGLLLDSYCRACGMYLKHLSRQVEAMEKLINLTDILKQ
EKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLWL
NWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSI
GDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDPAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAY
IRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A663LL94|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Athene cunicularia|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGKLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQSINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFHIVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSIQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C4L0G7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Equus asinus asinus|TrEMBL
MCFNFMMPPAMADSLDIWSVDSQIVSDGSIRVDFLLPTGIYIQLDVPREAPISYIKQMLW
KQVCDYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRVKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSNLENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIRGKEDE
VSPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEIAGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVNCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYTNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8D2G9T0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Theropithecus gelada|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A6J2DEB7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zalophus californianus|TrEMBL
MPPGLDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRGPTRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLYQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFRVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALSDFVKVSSQKTTKPQTKELMHLCMR
QETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDTQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A6J3HQ92|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sapajus apella|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRSCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKAMHRSPGQIHLVQRRAPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKYLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKAPAESPSSESKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCYPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIETLQKVTLDIKSLSAEKYDVSSQVIAQLKQKLENLQNSHLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSKETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEDKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSQHFQKFQDICVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8C0SLX3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYCFPLQLEPSARSWGP
GTLRVPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHG
NETLCKTVSSSEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKK
SKKADCPIAWANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAA
LVICLPEVAPYPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDL
VWKMRHEVQERFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDR
HVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWH
LRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQ
TKELMHLCMRQEAYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGS
DGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLH
SDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLG
IGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNS
EKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKVNARQMVAPTS
PRPTSGHCGLWSPEHGGAHRASPVWLPHATCDPTAGSGGDNLVLLHMCWDLPWATLLWLL
LYKRAELVTLPLCLKCFSSLCLFSLGEAGGS
>W5K9N9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MEQHISDDEPPAVPREENNKRRRRKMKAFTSATSVPVDHLVMEFVLPTTNKTTKNPDTVQ
LEVLGNWTVEQVKAQLWLRAVATNLCPEFYQKFSPDHTILLYQKKGSWCEIYDKHQVFQT
LDCIRYWKALKKEIGKIHLVLRPQSSEESVQYQKFLNHLIGYDVTDVSNVHDDELEFTRR
KLLTPRKIELADRDPKLYSMDPWITTKTLPDYLLSKITNGYILLVIHIGTSSQTIKVSID
DTPVQVLQSFFTKIANKRALLGIPEEVNESDFVLRVCGREEYIYGNYAIKDFHWIRQSLK
SGEEIHLVLEPPPNPEQDGVQKEDWSQVDDCTGVAGTHEQLTIDEKDHEKVFTISLWDCN
RKFRVKILGIDIPVLPRNSELIVFVEASVFHGQQQLAYERTSPKPFTEEVLWNTWLEFNI
KIKDLPKGARLNLQVSCSKAQTQTSRDSAVHDSKTKSRLLYYVNLLVIDHRSLLRQGEFI
LHMWKMPEKSAEDSSVNADKLTSATNPDKTSSMAIAVLLDKYCYPVALPKSRDSRDSSDM
EGERGKREMPNHLRKQFEQIVATDPLHPLSSEDKELLWHFRQDCMRHPSAYPKFLGSVKW
GKQEDVMATHQLLERSTTWDRSPLDVGLAMQLLDCHFSDANVRTMAVRKLETLGDDDVLR
YLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILE
AFLRGCGEVMLQDFSKQVEITEALQKITREIKAMSAEKYDVSPQVVLQLRQKLDSLQSSG
LPESFKVPFDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDL
RQDMLILQILLIMESIWETESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGN
TGAFKDEILNQWLRDKCVSEEKYQQAVDRFVFSCGGYCVATYVLGIGDRHNDNIMITESG
NLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTTGKKSSPNFLKFQDVCVRAYL
ALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGCSEDEAQKHFLDQIEICRDK
GWTVQFNWFLHLVLGIKQGVEKRSA
>A0A8C4U0V4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Falco tinnunculus|TrEMBL
MPPGIYCPTEFWAKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLHISTKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKTT
PKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQVGDTDAFLGRARPFILITTRDEMISLLQTWPELPVLNALELLDFSFPDRY
VGSFFLQVHLDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSE
MHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEM
MHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVG
IIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIA
NIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFER
FRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKVRETEPRYSYKPNTCS
CSLVGGGVQRGRGYYQKQVSNIWRSW
>H0VMM3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cavia porcellus|TrEMBL
MPPGVDCPMECWAEEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNRTAEQQELEDEQRRLCDVQLFLPVLRVVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRAKMRQFCEEAAVRRQQLGWEAWLQYSFPLQLEPSARSGAP
GPQPVPSRALLVNVKFEGSEESFTFQVSSRDMPLALMACALRKKATVFRQQAVEQPEDYA
LQVNGRHEYLYGSYALCQFQYICSCLHNGLTPHLTMVHSSSILAMRDEQGDPAPQVQKPR
PKPPPIPTKKPSSTSLWSLEQPFCVDLIQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANIMLFDYRDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESTAALVIFLPEVAP
NPVYYPALEKILELGRQGEQRGHPTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQ
EHFPEALARLLLVTKWHKHEDVAQMLCLLCSWPELPVLSALELLDFSFPDCHVGSFAIKS
LRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPS
VALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCM
RQETYLEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGSVGIIFK
NGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDHTGLIEVVLHSDTIANIQL
NKSNMAATAAFNKDALLNWLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MVRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGY
CERAYTILRRHGLLFLHLFALMRAAGLPELSSSKDIQYLKDSLALGKTEDEALKHFRVKF
NEALRESWKTKVNWLAHNVSKDNRQ
>A0A0Q3TM95|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amazona aestiva|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYILDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A671T371|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPAKTDQLDLWAESGLDGDVQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSCGEWLRSCYSTQLGTGSLE
NLIDKHEGDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDYVLRVSGRFEFLF
EDHPLNQCKVRYVVHSLFRINLVKGNKVNAEDAAKIQVRAGLFHGTELLCKTAVSSESSS
RSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIPWVNTMV
FDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVF
PAFDKVCIYSQYEHNSQMYTYTHKCTHVSFYIELKEIMERDPLSQLCENEKDLIWTLRYD
CRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAV
ICLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMYM
PAVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVSELIKLGTIKTKTKQAHLKEAM
MTCLRQTGFIETLSDLQSPLNPNILLAGVHVERCKYMDSKMKPLWIVYNNKLLGGDTVGI
IFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADTIAN
IQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGNF
RQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFR
QKFDEALRESWTTKVNWMAHIVAHPS
>A0A7L3XHV0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calonectris borealis|TrEMBL
MELGDYEQPVIMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQV
>A0A663E7B4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aquila chrysaetos chrysaetos|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHIWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHVKFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQCCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A672U2U0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MYSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQ
AHAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKL
DSKIGVLIGKGLHEFDALQDPEVHDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEP
VVPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEV
DPADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIE
AAVNRKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGT
ELLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMN
PSKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQT
NPYTENATALHIRFQEYAKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKE
IMERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPK
LLPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMK
TLNSLIKLNAMKQSKAKGKDAMQTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMD
SKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYG
CLATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3B5A1H7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Stegastes partitus|TrEMBL
MDGQQIQVSDEEPEVLREENRRRRRRKKAITSSSCSSMDQISVEFVLPTAARGGNGPDSL
LLEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQ
TLDCIRYWRALKKDVGRIQLVPRPQPSDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRRIELSDRDPNLYSMDPWVTRKPLPEHLHAKINNSHILVVIHISTASQTIKVSI
DDTPTQVLASFFAKTTNKRVLLGIPEHMCETDFVLRVCGREEYLYGEKPLQDFNWVRQCL
KNGEEIHLVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDC
NRKFRVKVLGIDIPSLPKVPEFIVFIEASIFHGQQLLAQERTTSKSFNEEVLWNCWLEFN
IKIKDLPKGARLNLQVSADVSLKAGTARKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWK
MPEKSDESSSSTNADKLTSATNPDKASSMAIAILLDKYCYPVVLPKTEGGERGQREMPNH
LKKQFGAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRWGRQEDVLATHRL
LERSSAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFE
PYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGENMLQ
DFRKQVEMTEALQKVTREIKAISTEKSDVTPQVVFQLRQKLETLQASGLPESFRVPYDPG
LRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQDMLILQILLI
MESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFKDEILCQW
LRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILG
NYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTNLLIIL
FSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQINWFVHL
VLGIKQGVEKRST
>A0A8C7H6H8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRVKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQLSKS
RSLSKPPPLPVKKLVVQAGLFHGSELLCKVVTSGEVNVCSEPLWDQKLVFDISVSDLPRM
SRLCFALYAVIEKAKKPRSTKKKNKKADCPLAWVNTMVFDYKDQLKTGEFLLSTWPSVPD
DKGDLLNPMGTVEKNPNVDSAAGLLIHFPNIRPHPLYYPHFDKVHLILHTHLQYVHSTPS
LLTLYCAAQHMKLKEIVDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKLLLITKWNKH
EDVAQMVTFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQLVQV
LKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGNIYH
IKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYKDALSYLLSPLNPS
IKLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIFKNGDDLRQDMLTLQMIQLMEI
LWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWL
KSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNF
KSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFA
MMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLA
KDSRL
>G7MJ92|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca mulatta|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
XXXXXXXGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C6F5V2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodon monoceros|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPLKKPVSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDISIGDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPIYYPALDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKLPVEKAKPPAFGAKTSGLKIL
WHWGRRRRRL
>A0A093HTB6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Struthio camelus australis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWSINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRENDKDQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLCRNIRKTLALDKTEQEALEYFMK
QMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K5F1E7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Probosciger aterrimus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GPLHIPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAIKKQATVFRHEIVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKTA
AKPPPLPKKKPNYGSLWSLEQSFYIQLVQGSKVNADEGMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWQQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAAEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMQSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKNNRQ
>A0A3P9H507|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETCYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDFEVQDFRRNILNVCKDAVELRDANGPHSRALYVYPPNVESSQELPKH
IYSKLDKGWVTGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSP
EQLKMCVQEYQGKYILKVCGFAVDHQRRSQDKNPLCHLRKCKYTGHRQGETSHVLRKKDS
SLGHTKKKK
>A0A7J5ZES7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dissostichus mawsoni|TrEMBL
MGGAGVKERKRTFTWRLKCWRTVPSRSEPQRAVLLHHCMNDSALDRRRETLRRFSGAVSV
RLSGTSPHFNFTDTSGERHVTVKRQRPSSLDLKHEEMTGAVTMPPGKYGMQEEWEKEGDQ
EIVMDFLLPTGIFLKFPVSPNDTIKTLKKMVWKNARSEALFSALGDPDAYVFTCINQTAE
REELEEEWRRISDIRPFMCVLRLVAREGDRVEKLTNTQISWLIGKGLHEFEAQKNHEVNE
FRTKMRAFCEEKAQERQMLPWQQWMEYSFPCDLEPCVSPPEYGSVKSKNTKKMFINVMFE
SSDESFMLQQDPQDPPVALMRSALKKKATVFRSVRQEPEDFTLQVNGTWEFIYGKHPLCQ
FKYIFHCIRNGQNPLVTMVHHSTIRRHQNDQGLCSQIYRNRSLSRPPPLPLKKQNTSSLW
SINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSEFLCKVVTTMEVSVCSEPLWDQKLEF
DINVADLPRMSRLCFALYAVIEKAKKPRGTKKKHKKADCPIAWVNTMVFDYKDQLKTGEF
LLSTWPSVPDDKTDLFNPMGTVEKNPNIDSAAGLLIRFPNIRPHPLYYPPLDKVGDIEKN
GEAANATKEELMKLKEIMDNKNYTEFFEDEKDLLWKLRTEVRDRYHESLSKLLLITKWNR
REDVVQMVSLLSNWRDLPTIHALELLDYSFPDPAVRSFTIRCLRKISDAELLQYLIQLVQ
VLKYESYLDCDLATFLLERALSNWRIGHFLFWHLSLISPTQIEALSKMKALSDFVKSGSQ
KMTADDLKLCIRQESYMEALSDLQSPLNPSVILADICADRCRFMDSKMKPIWLMYNPKVQ
EDMVGIIFKSGDDLRQDMLTLQMIQLMENLWKKEGLDLSSNSAATAAFNKDALLNWLKSK
NPEDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRK
LGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMK
AAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDN
RP
>A0A8C8XKJ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera leo|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEETP
CLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQL
RAICTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWP
PIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVR
FLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEK
LINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRI
MSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDL
RMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYD
AAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRER
VPFVLTQDFLIVISKGAQECTKTREFERKVFGIQNNLPQPFKQHVLNLKCILYFAKTRGR
NALLQLPTLAL
>A0A8B9F184|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amazona collaria|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQEPEVHDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRTTTSVWDISNPFKITLLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMQTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A2Y9KC41|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Enhydra lutris kenyoni|TrEMBL
MCVSFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSVLENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDQPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6A5EPZ6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Perca fluviatilis|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLLSIKQQLFTEARKYPLYH
LLQEESSYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNLESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVTHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPARSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLAYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDGEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMLKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFERFQEMCYKAYLPVCLPACLSLRFQEMCYKAYLAIRQHASLF
INLFSLLLGCGMPELQSFDDIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWI
FHTIRHMPNEH
>A0A8B6BSP7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mytilus galloprovincialis|TrEMBL
MPPVIVSPDLDVTSFQNDLGQLDIDFLLPNGICVPLQVDIDRPLDQIKQELWKQAANYPL
FQQLATFDKYGFLYISGEGQKEDVMDESVGISELRLAASFLKVVEKPADDKRKTIDRQIN
SLIGMKGSNYIQAQHSVSKAEISEFRQKMTTYCNNDVLKQANQDPTGLVYFEYKHPCRLR
STSELPPDVENMVIDYIVLTVIVQETGTSYKLRVKKLSTPDELVKMTVDKWSSKSGQKTI
NCNDYVLQVLGMNDFLYGDNPLVMFKYVYSCIVKNTAPEFWLKNKSSVLEKQEVSQPHKS
SRTSFQEERRNTVRSEKRSGHCVWDIHQNFYITLHTACNVQVPENCRNLVRLCVGVFHGP
DPLCSIQETKEVFVSQDGLCSFNDCINFDIKVQDLPQMSRLCFGLHCKKGKEPLLLAWAN
IPIFDYKSNLQKGKLKLPLWPRSELIQQEESYCFPVGTVATNPQGDCSMIEFSVPDFTKK
GSIYYPPIEKVLELASTYIEAPGMPGSTTWRPNKNIVQQLDSILRANQYTILQTLDEQQK
QLIWWMRYDIRDKCSEFPHALLYVLYSVSWDNHIEVSKMQALLQTWPTLEADQALTLLDF
TFPDKYVRKKATEWLDELPDEELAQYLLQLVQALKYENYLNCDLVKFLLRRALQNRNIGH
KLFWLLKSDMHEPSVTVQYGLIIEIYLKANPSHMSILDRQQIILQKLKSITDIHTKAANL
KKKAKEKDDSPLQKVMQQSAYKEAFCKIYSPITLMYKLDKIVEKSCKVMDSKKKPFWLEW
TNDDEKGQNIQLIYKCGDDLRQDMLTLQILEVMDTIWQSEGYDLRLNPYGCVATGCEEGM
IEVVQKSLTLAGIQKWRKLGLDKRSLYDWLKHKNPSEHSLQRAVEEFKLSCAGYAVATYI
LGVGDRHNDNIMMKETGQLFHIDFGHFLGNKKTKFNINRERVPFILTSHFEYIIKDGEKK
PQNFTDFKEICERAYLIIRSRAHLLIQLFMMMLSSGIPQLNNVSDIDYIKEVLALNSTQE
EALEKFRKKFKEAQDNSWSTTVNWWFHMRVH
>A0A673GEF2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVEMRDASGPHSQIIVVIWVIVSPNNDKQKY
TLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLKMCVQEYQGKYILKVCGCDEYLLEKYPI
SQYKYVRSCIMLGRLPNLISTISSLPCQSLTRFYVSFSTIKTKKIESNREIKTQPYYLQC
FNSACFINEHLNDLLQEHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGV
TGSNPNKETPCLELEFDHFSSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDH
AMTEADIEQLRQLSNRDPLSEITEQEKDFLWRHRQYCVNIPEVLPKILLAVKWNSRDEVA
QMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVRLI
YSTPFLNQACIFTVQLKAALSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKL
INLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIM
SSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLR
MLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDM
AIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERV
PFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMP
ELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A673LC45|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MILKSYNVIDDEPPVVRREENKRRRRKMKAFTSTSAVSTDHIAVEFVLPTTNKNSRNPDT
LHIDVTGNWTVEQVKVQIWHRAVTTKLYLKTLLASVFVLLTSKQLWYEIYDKQQVFQTLD
CIRYWKALRKEVGKIHLVVRTQPTEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRKL
LTPRKIELSDRDPKLYSMDPWMTTKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDDT
PVQVLQSFFAKITNKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKNG
EEIHLVLERPPDPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRK
FRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIKI
KDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVDHRSLLRQGEFILHMWK
MPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDQYCYPVALPKSKDSPDSEMEGERGQ
REMPNHMRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEAV
TITHRLLERSTVWDRSSLDVGLALQLMDCHFSDENVRTMAVRKLETLAGDDVLRYLLQLV
QAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGC
GEAMLQDFRKQVEMTEALHKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDSFK
VPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDMLI
LQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKD
EILSQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHID
FGHILGNYKSFMGISKERVPFVLTPDFLYVMSTTGKKSSPHFLQFQSVCLKAYLALRHHT
NLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQF
NWFLHLVLGIKQGVEKRSA
>A0A673IC43|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYSMPLEAGSLE
NLIDKHEGVIKITMHYDQSQVLSLHCTVTELMDQALKKWQTTHGPEEDIGFRSDYVLHVS
GKLEFLFEDHPLNQCKVRYVARNGFESSNYIFQGFVNMVKIQHSTTYCFRAMCSLKFQEI
STIGSVLARKTSNPPLPLPPKKRLPTASTLSGLFHGTELLCKTAVSSESSSRSEHVWNKT
LEFDIAVCDLPRMARLCFAIYAVMDKVKKPRSTKNTHLNKYQTIPWVNTMVFDYRGQLKT
GDIILHCWTSFPGEKTHMLNPIGTIQTNPYTENATELHINFPEYSTQPVVFPAFDKGRGG
KKFYIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQL
QALLQIWPKLSPRDALELLDFNYPDQYVREFAVYCLQDMSDDELLQYLLQLVQVLRYEPY
YDCALSRFLLERSQSSRKIGHFLFWHLRSEMFMPAVSVHFALILEAYCRGCIPHIEVLKK
QVEALSKLKAVNELIKFGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLA
GINVERCKYMDSKMKPLWIVYNNKLLEGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKE
ANLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKN
SGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKF
GIKRERVPFILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLT
AGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A444UAM9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acipenser ruthenus|TrEMBL
MEQHGDDEQPVIFREENKRRRRKMKAFVSSNTVVTMDQIAIEFVLPTYNKFNKIQDALML
DVAGNCTVEQVKTQLWMKAVERSACPEFYQKYTPDQCILLYQKKGHWYEIYDKHQVFQTL
DCIRYWKALKKDLGRIHLVTRPQPTEESEQYQRYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRLIELANRDPKLYSMDPWITPKPLPEYILNKISNNNILVVIHRGNASQTIKVSIDD
KPDQILQNFFTKIAKKKPLLGISEEDSELDFVLRVCGRDEYIFGDNPVKNFYWVRQCLKN
SEEIHLVLESAPDPEQDVVHKEDWSLVDDCTGVAGSHEQLTIEEKDHEKVFTISLWDCNR
KFRVKVLGIDIPMLPRNSELIVFVEASIFHGQQLLAQQRTSSKPFTEEVLWNTWLELDIK
IKDLPKGARFSLQVYCGKTQTQSTKAGFQESINFDSKCKNRLLYYVNLLLIDHRSLLRQG
QYVLHMWKMPEKSEDHSSVNADKLTSATNPDKETSMAITVMLDKYCYPIALPKGQESVEV
EGERSRREMPNHLRKQFEKIVATDPLHPLTPEDKELLWHFKQECMKCPKAYPKFLSSVKW
GKQEAVLATHQLLEKHDAWDRSTLDVGLAMQLLDCHFSDENVRTVAVRKLETLGDDDVLR
YLLQLVQAVKFEPYHDSALARFLLKRALRRKRIGHFLFWFLRSEIAQSMHYQQRYAVILE
AYLRGCGEAMLHDFKKQVEITEALQKITKEIKAMSADKYDISVQVVSQLRQKLEKLQTSG
LPRSFKVPYDPGLRAGSLVIEQCKVMASKKKPLWLEFKPDDPTTRSSDTIGIIFKDGDDL
RQDMLILQILLIMESIWETESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGN
TGAFKDEVLNQWLGDKCVMEDKFQQAVERFVFSCAGYCVATYVLGIGDRHNDNIMITESG
NLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTFGKKTSPQFQKFQDVCIKAYL
ALRHHTNLLIILFSMMLMTGMPQLTSTEDIEYIREALTVGKTEEDAEKHFLDQIEICRDK
GWTVQFNWFLHLVLGIKQGVEKRSA
>H2QNG6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan troglodytes|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRALPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMRYLLAKFKEGKRFMGDEELSQYLLQLVQVL
KYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHM
KVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCV
ILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLL
WKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLK
EYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFK
SKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFAL
MLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRK
DYRS
>A0A8C0ZGV3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyanistes caeruleus|TrEMBL
MKILPRADHHSGISSGMELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFIL
PTSNKHTKAPEIMLLEIAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKG
QWYEIYDKHQLLQTLDCILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTD
VSNVHDDELEFTRRRLVTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIII
HRGTTSQKIKVSIDDTPDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGE
TPIKDFHWIRQCLKNGEEIHLVLDNPPDPNEDEVRKEEWPLVDDCTGVTGYHEQLTIDGK
DHERVFTISLWDCNRKFRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPF
TEEVLWNIWLEFDIKIKDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLL
YYVNLLLIDHRFLLRSGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLD
KYCHPIALPKHRISSDPQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYE
SIKHPKAYPKLLSSVKWGQQEIVAKTYQLLAKKEIWDQSTLDVGLTMQLLDCNFSDENVR
AMAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRS
EIAQSMHYQQRFAVILEAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTS
QVIAQLRQKLEKLQGSKLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPT
ALSNETIGIIFKHGDDLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEI
VKDATTIAKIQQSTVGNTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFV
LGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKK
TSLHFHKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSE
EDAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C0VJM5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyanistes caeruleus|TrEMBL
MPPGIYCPTEFWSKGEHQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRSKMCQFCEEKAAKRQQLGWAAWMEYNFPLQLEPMAKGPGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQNSCFTSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLDFDINICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
AAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6F9A2Y1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coregonus sp. 'balchen'|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMIVTLECTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVTIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQYLDNPLARFLLKKALTNQRIGHF
FFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLKQEKKDE
AQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWENP
DMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVG
LIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRSCAGYCV
ATFILGIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCY
KAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMND
AHHGGWTTKMDWIFHTIRQHAMN
>A0A3Q3H035|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Labrus bergylta|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNLESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPARSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYTDVLVSGKVALGLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDDQQIEEHANWTISRELGYTYCHGLTGRLACDSSVSATDGEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKSSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMLKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKTQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>U3K6Q5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ficedula albicollis|TrEMBL
MELRDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHEYSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GDYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQEAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K9NMV6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Edolisoma coerulescens|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQCILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKVIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNTWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTSLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L3VCV0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Molothrus ater|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPTKNIFVNIRFQSGGESFMFQISPWEFPITLMSYAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFDIR
DQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREAFSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQVTGRHLGRARWAPGHGLCPKQGTWAWAWALPKAGHAGSPHSFVWSLLLLRFRDY
CERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKF
NEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L0IG19|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Piprites chloris|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKLPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQSTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQQPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPNPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDTKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKDVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLYDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8B7UMR6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Castor canadensis|TrEMBL
MELENYDQPVVLREDNLRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRHSKTPETALLH
VAGHGNVEQMKAQVWLRALEISAAADFYHRLGPDSFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRRVPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPEYLLKKIANNCIFIIIHRSTTSQTIKVSADDT
PGIILQSFFTKMAKKKSLMGIPESLNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLIVFVEANIQHGQQVLCQKRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKTPALSGKVSAETHSSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEGD
RVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPEAYPKLFSSVKWGQQ
EIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLL
QLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYL
RGCGMAMLQDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLPQ
SFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQD
MLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGA
FKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLF
HIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSSHFQKFQVCVKAYLALRH
HTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTV
QFNWFLHLVLGIKQGEKHSA
>A0A8C8GLV4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHEVFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKCPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGESSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRYYRHTTHMGDSLWLCLSPRWNEWLTYDMYIPDIPRAAR
LCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGV
TGSNPNRETPCLELEFDYFSSPVKFPDMTTVEGHANWTISRELGFSYCQSGQSNRVARDH
ALTDSDNEQLRQVCNRDPLSEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVA
QMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKY
EQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKH
LSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQL
GNIRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIME
NIWQNQGLDLRMLPYGCMSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWL
KDKNKGEMYDLAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHK
KKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINL
FSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHT
IRQHALN
>A0A7M4ESA7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crocodylus porosus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWSLNSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMFILELPRAARLCLSICSVKGRKGAKEVKC
FRQGVHIYTCPNILNCASLPPLWVEGPDPETPCLELEFDWFSSPVKFPDMTVIEEHANWA
IARELGCNYSHAGLSNRLARDIEVRESDKEQLRAICTRDPLSEITEQEKDFLWSHRHNCV
NTPEILPKLLLSVKWNSRDEVTQMYCLIKDWPPIKPEQAMELLDCNYPDPMVRSFAVQCL
EKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKT
VSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQM
RRPDFMDALQGFISPLNPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMSELLFQNNEI
IFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQ
IQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRSCAGYCVATFILGIGDRHNS
NIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFER
FQEMCCKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYF
MKQMNDAHQGSWTTKMDWIFHTIKQHALN
>A0A7K6YZY5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alca torda|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVRDPEVNDFRAKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GPLHTHTKNIFVNVRFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A671U0C0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MPPGKYGMQEEWEKEGDQGIVMDFLLPTGIFLKFPVSRHDTIKSIKKMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEVKAQERQALPWQQWMEYSFPCDLEPCSSPPVC
GSVKSKNTKKIFINVKFEACDESFMLQQDPQDLPVALMRSALKKKATVFRSVRQEPEDYT
LQVNGSWEFIYGNHPMCQFKYIFSCLRNGQNPHLTMVHHSTISKYQEEQGRMCSQVFKSR
SLSRPPPLPLKKNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SSEVTVSSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFSNIR
PHPLYYPPLDKISDVERNGDAAIATKEEVISYFLILTRSRSGLLLFFEDEKELLWKLRTE
VRDRYPESLSKLLLITKWNKREDVSFDSPQMVSLLRNWPDLPAIHALELLDYSFPDPAVR
SFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLATFLLERALSNRRIGHFLFWHLRS
EIHVASVSLRFGLILEAYCRGNIQHIKLLTKQNEALGKMKALSDFVKSGSQKMTVDDLKL
CIRQESYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNTCAQGDMVGIIF
KNGDDLRQDMLTLQMIRLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQ
RNSSNSAATAAFNKDALLTWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDN
IMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRE
YCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVK
FNEALRESWKTKVNWMMHSLAKDNRP
>A0A671U1R0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MPPGKYGMQEEWEKEGDQGIVMDFLLPTGIFLKFPVSRHDTIKSIKKMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEVKAQERQALPWQQWMEYSFPCDLEPCSSPPVC
GSVKSKNTKKIFINVKFEACDESFMLQQDPQDLPVALMRSALKKKATVFRSVRQEPEDYT
LQVNGSWEFIYGNHPMCQFKYIFSCLRNGQNPHLTMVHHSTISKYQEEQGRMCSQVFKSR
SLSRPPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVSSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFSNI
RPHPLYYPPLDKVLILKGFFSGYKLIFEYLKEIMDNKNYTEFFEDEKELLWKLRTEVRDR
YPESLSKLLLITKWNKREDVVQMVSLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLR
KLSDDELLQYLIQLVQVLKYESYLDCDLATFLLERALSNRRIGHFLFWHLRSCVSAAFCL
IEEFALCLKSPAQNEALGKMKALSDFVKSGSQKMTVDDLKLCIRQESYLEALSDLLSPLN
PSIILTEICADKCRFMDSKMKPLWLMYKNTCAQGDMVGIIFKNGDDLRQDMLTLQMIRLM
ENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLT
WLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLG
NFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNL
FAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHS
LAKDNRP
>A0A671UL32|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMLKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSTQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQSAGLCPNRLF
>A0A8C9Q1B3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Spermophilus dauricus|TrEMBL
MPLGIDWPMEFWTEVEKNRSVVVDFLLPTGIYLSFPVSRNANLSTIKQMLWHKAQNEPLF
HMLSDPKAYVFTCVNQTAEQQELEDEQQRLCDVRPFLPMLRLVTRQGDRMEKLINSQISL
LIGKGLHEFDCLQDPEVNDFRTKMCQFSEEAAAHRQQLGWEAWLQYSFPLQLEPSTRSWG
DSNTSQISNPDLLVNVKFEGSRESFTIQVSTKDVPLALMACALQKKAKVYQHLTMEQPED
YVLQVNGRHEYLYGSYLLCQFKYICSCLHSGQTPHLTMVHSSSILAMRDEQSRPAPQVQK
PHTKPPPIPMKKLVVQAGLFHGNEMLCKTISSLEVSVCSEPMWKQHLEFDINICDLPRMA
RLCFALYAVMEKAKKAYSSKKKSKKEDCPIAWANLMLFDYKDQLKTGELCLYMWPSVPGG
PRPSRERLLEGEASRTGSPTTTSLLPSDEKGDLVLNALELLDFSFPDCHVGSFAIRSLQK
LTDDELFQCLLQLVQVLKYKSYLDCELTQFLLDRALANRKIGHFLFWHLRYSEMHVPSVA
LRFGLIMEAYFRGSTHHMKVLMKQVEALSKLKALSDFVKVSSQKTTKPQTKELMHLYMRQ
DTYLEALSHLQSPLDPSTMLAEVCVERCTFMDSKMKPLWIMYSSEEAGSADSVGIIFKNG
DDLRQDMLTLQMIQLMDALWKQEGLDLRMTPYGCLPTGDCMGLIEAVQHSDTIANIQLNQ
SNLAAMAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCARYCVATYVLGIGDRHSDNIMV
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTHDFVHVIQQGKTSDNEKFERFRGYCE
QAYSILQRHGLLFLQLFTLMQAAGLPELSSSKDIQYLKDTLALGKTEEEGLKHFRVKFNE
ALRESWKTKVNWLAHNLTKDNRQ
>A0A7K9PN04|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pachycephala philippinensis|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSAEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWITSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNTDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6Q2Y3G3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLTSIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGRL
IVTIWVIVSPSNSKQKYTLKISHDSLPEQLIAEAIRKKTRSMHLSAQQLRLCVQEYQGQY
ILKVCGCDEYLLEKYPLSQYKYVRGCITMGRLPHLMLVSKDSLYSQLPGSGFVAPSYSRR
TPQPSPCPGGGDPSTPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRTGIYHGGEPLC
DNVNTQRVPCSNPRWNEWLSYDIYLTDLPRSARLCLSICSVKGRKGAKEEHCPLAWGNVN
LFDYKDTLVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFSWFNQVVLFPD
EQQIEEHANWTISRELGYNYCLGLSSRLACDSSVSVADGEQLRSLCSRDPLYELSEQEKD
FLWRHRHYCVNIPESLPKLLLSVKWNSRDEWSQMYCLLRDWPLMQPESALELLDCNFPDP
MVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFFW
HLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQK
TQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWDNPDIM
SELLFTNNEVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIE
VVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTRSCAGYCVATF
ILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQ
ECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALE
KSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A851MQZ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Campylorhamphus procurvoides|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAARRQQLGWAAWMEYNFPLQLEPLAKGFGT
GSLQTPTKNIFVNVKFQSGRESFTFQISPKELPLTLMSYAIKKQATVFRHETLQRAEDYT
LQVNGKWEFLYGSHPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAP
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMIFLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2K5E2S4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aotus nancymaae|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTITLLWHRAQYEPLFHM
LNGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLLI
GKGLHEFDSLCDPEVNDFRTKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGPG
TLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYTL
QVNGRHEYLYGSYPLCQFQVQKPRTKPPPIPAKKPSSVSLWSLDQPFCIELIQGSKVNAD
ERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDISISDLPRMARLCFALYA
VIEKARKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPT
GTVRSNPNTDSAAALLICLPEVAPYPVYYPPLEKVRAILSVGTLPELLWLSLHARDSAPS
RMIGVETPCLGIPPGLVQAPRTLRLGRHSECVRVTEEEQLQLREILERRGCGELYEHEKD
LLWKLRHEVQERFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLGALELLDFSFPD
CHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFW
HLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKP
QTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAS
SGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVL
RSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVL
GIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNN
SEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEE
EALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q3K4L1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monopterus albus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDSVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYSQLPTD
NFAMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVASKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRQFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEIHNKTASQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A7K6NUF7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pedionomus torquatus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQPFHIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGDQPRATPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGRGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3B4U6T9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola dumerili|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TLPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRVTEEKMQRVQKMTFAEWLQACFSPQLEPA
AGTAITDGVNDRSPDLKVTIHFDQSQDSASLKVPSSCTPTELMELAVRKWLTTHGPEEEA
WRGQYVLRLSQCLEFLFGDHPLIQYKYIRTCIQAKESPHLTLVHTSTVKAMFDREMSTIG
AVVSRKSSNPPLPLPPKRRVPTTCVWDVSCPFKIVLVNASKVNAEETAKVQVRAGLFHGT
ELLCKPAVSSESSGRSDHTWKESMLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNP
HINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDINLHCWSSFPDELEEMLNPIGTIQ
TNPYTENATALYIHFPEYSSHAVIFPPFDKILEKAAEIARASDCAPMGRGGKKFHIELKE
IMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPK
LSPRDALELLDFNYPDQYVREYAVRCLRDMSNEELSQYLLQLVQVLRYEPYYDCALTHFL
LERAQGNRKIGHFLFWHLRSEIHMPAVSIQFALILEAYCRGSIPHIEVLKKQVEALSKLK
SVNELIKLGTTKNARSKTKEAMLTKEAMMTCLRQNTNVHVTECRYMDSKMKPLWIVYNNK
LMGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEASLDLRIVPYGCLATGDRAGLIEV
VSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFTLSCAGYCVATY
VLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKT
GYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKT
DDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A3B4TY69|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola dumerili|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGRL
IVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLRLCVQEYQGQY
ILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPASGFVTPSYSRR
TPQPSPCPGGGDGCPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRTGIYHGGEPLC
DNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEEHCPLAWGNVN
LFDYKDILVSGKVALGLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFSWFNQTVVFPD
EQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDAEQLRSLCSKDPLYELSEQEKD
FLWRHRHYSVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESALELLDCNFPDP
MVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFFW
HLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQK
TQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIM
SELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIE
VVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTRSCAGYCVATF
ILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQ
ESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALE
KSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A8C9GCH4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Piliocolobus tephrosceles|TrEMBL
MPPGVDCPMEFWTKEENQSIVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAIRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
TEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKCKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVHSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C6YTR7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothoprocta perdicaria|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLEXLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWSINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYEMYITDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A4W5QMH1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MPPRPSSGELWGMHLMPPSIQVDCLLPNGMILTLVCTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANCNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCGTIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQVLQTTGPATL
>A0A8C6ZZZ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothoprocta perdicaria|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSGNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHMFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTSLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
LPGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSALDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVLL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITEA
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3Q0QVY8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amphilophus citrinellus|TrEMBL
MAPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLTTVKHELFKEARKYPLYS
LLQEESSYIFVSVTQEAEREEFYDETKRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDLEVQDFRRNILNVCKEAVDLRDSNGPHARALYVYPPNVESSAELPKH
IYSKLDKGQIIVVIWVIVSPTNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPME
FFTMPSYARRISTATPYMNGETATKCLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTIRVPCSNPRWNEWLTYDMYIPEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHY
SCPVKFPDMAIIEEHANWNISRELGFNFCHTGLSNRLARDNPLTESDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHDCINMPEILPKILQAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMVREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8C7SGQ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MVWRNASSEPLYGALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGD
RVEKLTNTQISLLIGKGLHEFDSQKNHEVNEFRTKMRSFCEEKAQDRQRLPWYQWMEYSF
SCDLEPCVSLAEPGGIKTKGTKKIFVNVKFEASDVSALFLWPFLLLFLMFVLVNQSVTFL
RQEKPEDYTLQVNGRWEFIYGKYPLCQFKVSKHNNTTHVLFLSYYQQNTSSLWSIEEPFH
IHLLQGYRVNADEGMKVGVAGLFHGSELLCKVVTSGEVNVCSEPLWDQKLVFDISVSDLP
RMSRLCFALYAVIEKAKKPRSTKKKNKKADCPLAWVNTMVFDYKDQLKTGEFLLSTWPSV
PGDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPHFDKVHLILDLEKNGGKVIATK
LKEIVDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKLLLITKWNKHEDVAQMVAFLQK
WPDLPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQLVQVLKYESYLDCDLA
TFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGNIYHIKSLCKQNEALN
KMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLLSPLNPSIMLSEICADRCK
FMDSKMKPLWLMYKNKWVQGDTVGIIFKNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMI
PYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEDKLDQA
IEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVP
FILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSS
FKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDSRL
>A0A8C2X2S2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MPSGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNASSEALFG
ALGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRMFCEEKAQERQMLPWQQWMKYSFPCDLEPCCSPPEY
GSVNGCLLLALMCLSQESFMLQQDPQDLPVALMRSALKKKATVFRSLRQEPEDYTLQVNG
RWDFIYGKHPMCQFKYIFSCLRNGQNPYLTMVHHSTIHKYQEDQGSMYNQVYKSRSLSRP
PPLPLKKVRVHCSSTSELLCKVVTTSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALY
AVLEKAKKPRGTKKKNKKAVSLSSRFGDCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPD
KSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPLDKVPIPKGLYLEIMDNKNST
EFFEDEKELLWKLRTEVRDHFHESLSKLLLITKWNRHEDVVQLVSLLKNWRDLPGIHALE
LLDYSFPDPAVRSFTIRCLRKLSAIIIFSAHSDNELLQYLIQLVQVLKYESYLDCDLTTF
LLERALSNWRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIRLLTKQNEALGKM
KALSDFVKSGSQKMTADDLKLCIRQESYLEALSDLLSPLNPSIILAEIWLVADKCRFMDS
KMKPLWLMYNPGAQEDMVGIIFKKGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCL
STGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDPAIEEFT
LSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTY
DFVHVIQQGRTNNSEKFERFREYCERAYKILCRNATLFVNLFAMMKAAGLPELTSFKDIQ
YLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A8C7TJE0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MPPAMTDDLDLWAAHSQLCGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFCPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQACFSPQLEPGGG
ATPVTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISA
IGAVVNRKSSNPPLPLPPKRRGPSQVNTCVWEVSSPFKIVLIKGSKVNAEETAKVQVRAG
LFHGTELLCKPAVSSESSGRSEHVWNRTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKS
TKNAHINKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPI
GTIQTNPYTENSTALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCSSMGRGGKKFHI
ELKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQ
IWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCAL
TRFLLNRAQCNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYSRGSIPHIEVLKKQVEAL
SKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSG
IKVIWDVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLL
WKEANLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLK
EKNSGDALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFK
SKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFAL
MLTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVK
DNRS
>A0A8C7UQW7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MPPRPSSGELWGMHLMPPSIQVDCLLPNGMILTLVCTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANCNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCGTIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A6J3RC01|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tursiops truncatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRRLVPGPPP
MPESTDAQVPYIKWRSICI
>A0A8C7WJR7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MEQQVSDEEESQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFN
IRIRDLPKGARLSLQVSCGKAQTQISKGTSSYQDNGGSPVGGGSGSHDCNKTKSRLLYYV
NLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYC
YPVALPKSREGKEAGGEGREAEGGERGQREMPNHLRKQFEAIVETDPLHPLSQEDKELLW
HFREECMRHPRAYPKLLGSVRWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYS
DAHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLF
WFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEK
YDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFK
RADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKI
GMIEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYC
VATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMG
TSGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALT
VGRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A287DBQ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ictidomys tridecemlineatus|TrEMBL
IPLGIDCLMEFWTEEEKNHSVVVDFLLPTGIYLSFPVSYNANLSTIKQVLPGLLSNEPLF
HMLSDPKAYVFTCVNQTAEQQELEDEEQRLCDVRPFLPMLRLVTREGDHMEKLINSQISL
LIGKGLHEFDSLQDPEVNDFCTKMRQFSEETAARRQQLGLEAWLQYSFFLQLEPSTRSWG
DSNTSQIFNPDLLVNVKFEGSRESFTIQLSTKNVPIALIACALQKKTKVYQNLTMEQPED
YVLQVNGWHEYLYGSYLLCQFKVRSLLHSGLTPHLTMVHSSSILPSSVSQWSLGQPFCIE
LIQGSKINADEQMKLVVQAGLFHGNEMLCKTISSLEVSRMARLCFALYAVIEKAKKAHSS
NKKSKKDCPIAWANLMLFDYKDQLKTGELCLYMWPSVPGGPRTGSPTTTSVPQSQHRECC
HPGYLPQLQLQGILEQRGSGELYEHEKDLVWKMQHEVQEHFPEALAHLLLVTKWNKHEDV
AQMLYLLCSWSELPVLNALELLEFSFPDFHVGSFAIRSLQKLTDDELFQCLLQLVQVLKY
KSYLDCELTQFLLDRALANQKIGHFLFWHHRTEMHVPSVALRFGLIMEAYFRGSTYHMKV
LMKQVEALSKLKALSGFVKVSSQKTTKPQTKELMHLYMRQDTYLEALLHLQSPLDPSTML
AEVCVERCTFMDSKMKPLWFLYSSEEAGSAGSIGIIFKNRDDLCQDMLTLKMIQLMDALW
KQEGLDLRWGLYPSPDDLLWLPIHGDCMGLIEAVQHSDTIANIQLNQSNLAATAAFNKDT
LLNWLKSKNPGSSPSEFTLSCAGYCVATYVQGIGDRHSDNIMIRENGQLFHIDFGHILGN
FKTKFGINRDNNEKFERFRGYCEQAYRILRRHGLLFLQLFALMRAAGLPELSSSKDIHYL
KDTLALGKTEEEGLKHFWVKFNEALSESWKTKVNWLAHNLTKDNRQ
>A0A8C2X696|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MPSGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNASSEALFG
ALGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRMFCEEKAQERQMLPWQQWMKYSFPCDLEPCCSPPEY
GSVKSKNNKKIFINVKFEACDESFMLQQDPQDLPVALMRSALKKKATVFRSLRQEPEDYT
LQVNGRWDFIYGKHPMCQFKYIFSCLRNGQNPYLTMVHHSTIHKYQEDQGSMYNQVYKSR
SLSRPPPLPLKKQNTSSLWCISEPFYIHLLQGSRVNAGEGMKLVVQAGLFHGSELLCKVV
TTSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVLEKAKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIR
PHPLYYPPLDKVPIPKGLYLEIMDNKNSTEFFEDEKELLWKLRTEVRDHFHESLSKLLLI
TKWNRHEDVVQLVSLLKNWRDLPGIHALELLDYSFPDPAVRSFTIRCLRKLSDNELLQYL
IQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLRSEIHVASVSLRFGLILEAYC
RGNIHHIRLLTKQNEALGKMKALSDFVKSGSQKMTADDLKLCIRQESYLEALSDLLSPLN
PSIILAEICADKCRFMDSKMKPLWLMYNPGAQEDMVGIIFKKGDDLRQDMLTLQMIQLME
NLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNW
LKSKNPEDKLDPAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGN
FKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNATLFVNLF
AMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSL
AKDNRP
>A0A7K4ST80|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Burhinus bistriatus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GPLHTPSKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQIWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSQKATKPQTRELMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDTLEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A0N8JXZ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MAPGVYCLPNMWEGGVQQVKMDFLLPTGIYLSFGVSGNDTIGAIKKTLWRNAKNEPLFFA
LSDPDAYVFTCINHTAEQEELEDEQRRLCDVRPMMPILRLVAREGDRVEKLITSQISLLI
GKGLGNLRNRASKKIIVNVKFEASDESFTLQVEPQEVPLTLMKSALKKKATVFRPMKQEK
PEDYALQVNGRWEFIYGNFPLCQFKYIFNCLHSGVTPHLTMVHYSTITKYQEEQGGISRE
ISKNRSSSKPPPLPLKKQTMSSLWSIQDAFSIHLMHGSRVNADEGMKLVVQAGLFHGSEL
LCKVVTSSEVNVCSEPVWDQKLEFDINVCDLPRMTRLCFALYAVIEKSKKPRSTKKKNKK
ADCPLSWVNTMVFDYKDQLKTGEYYLSTWPSVPDDKTDLLNPMGTVEINPNTDSAAGLLI
RFQNVRPHPIYYPSLDKINDFMINGKKSVATKEEHLKVSEIVENKNYTEFFEDDKEILWK
LRYEVREKYSESLSKLLLITKWNKHEDVAQMVSLLQKWPDLPALHALELLDYSFPDRNVR
SFTISDDELFQYLLQLVQVLKYESYLDCDLTKFLLERALSNKKIGHFLFWHLRSEMHVPS
VNLRFGLILEAYCRGSIYHMKTLMKQNEALNKMKSLNDFVKSASQKGTRTQTTGEMKKCI
KQETFMEALSDLLSPLNPSLILSEICPDRCKYMDSKMKPLWLVYKNEKVQGDPLGIIFKN
GDDMLTLQMIQLMEILWKKEGLDLRDKLEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYC
EQAYKILCRNGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFN
EALRESWKTKVNWMVHSVSKDNR
>A0A484GKU5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sousa chinensis|TrEMBL
VAEGMELENHEQHVVLREDNRRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRNTKTPET
ALLHVAGHGNVEQMKAQVWLRALETSVAADFYHRLSPDHFLLLYQKKGQWYEIYDKYQVV
QTLDCLRYWKVLHRSPGQIHVVQRLAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFT
RRRLVSPRMAEVAGRDTKLYAMHPWVTSKPLPEYLLKKITNNYIFIVIHRSTTSQTIKVS
ADDTPGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIRNFQWVRQC
LKNGEEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWD
CDRKFRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEF
SIKIKDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLR
HGEYVLHMWQLSGKAEDHGSINADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTP
DPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSV
KWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDV
LHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVI
LEAYLRGCGTAMLHDFTQQVQVIDMLQKVTMDIKSLSAEKYDVSSQVISQLKQKLEILQN
LNLPQSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGD
DLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTV
GNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISE
TGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSRHFQKFQDVCVKA
YLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCR
DKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A8C3GJC4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cairina moschata domestica|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKSFGT
GLLHTPTKNIFVNVKFQSGGESFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANTPKMS
PKPPPLPKKKPNYSSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPSVAS
HPVYYPSFEQLLELGRNGEPPRTALEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDNELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDTLEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A096LPQ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia formosa|TrEMBL
ITMPPGKYGTQEEWEQDGDREIYMDFLLPTGIFLKFPVSRNDTIRNIKKMVWKNASREPL
FFGLGDPDLYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRSEKLTNAQIS
LLIGKGLHEFEAQKNHEVDEFRTKMRTFCEEKSLERQNLPWQRWMEYSFPCELEPCSSPA
TGGSSKSKHGKKLFVNIKFESSDESFMLQQDSQDLPVALMKSALKKKATVFRSVRQEPED
YTLQVNGRWEFIYGQHPLCQFKYIFFCMRNGQNPQLTMVHHSTISKYQEDQGRVCSQMYK
TRSLSRPPPLPLKKSKIILNILSNSINEPFYIHLVHGSKVNADEGMKLVVQAGLFHGSEL
LCKMMTSSEVTVCSEPLWDQRLEFDINVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKS
KRKMICSENQNDCPIAWVNTMVFDYKDQLKTGDFLLSMWPSVPDDKSDLLNPMGTVQKNP
NVDSAAGLLIRFPNIRPHPLYYPPLEKIFSVTVHCCSSERNINFLPPTHYLKLKEIMDNK
NYTEFFEDEKELLWKLRIEVRDYFPECLSKLLLITKWNKREDVVQMVSLLKSWPELPAIQ
ALELLDYSFPDPAVRYFTIRCLKKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERAL
SNRRIGHFLFWHLKSEIHVASVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDI
VKTGSQKMTVDDLKLCIRQESYLEALSDLLSPLNPSVILFEICADKCRFMDSKMKPLWLM
YKNPLEQADMVGIIFKNGDADLRQDMLTLQMIRLMENLWKKEGLDLRMIPYGCLSTGNKM
GLIEIVKSSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGY
CVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVI
QQGRTNNSEKFERFREYCEKAYKILCRNGTLFVNLFAMMKAAGLPELSSSKDIQYLKDSL
ALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A8C5QU16|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptobrachium leishanense|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMMVVLECLREATLINIKHELFKEARKYPLHH
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRKNILNVCKDAVELRDANGPISRALYVYPPNVESSPELPKH
IESKLDKGQIIVVIWVIVSPNNEKQKYSLKINHDCVPEHVIAEAIRKKTRSMLLSTEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKDSLYSQIPVD
TFTMPSYSRRISTATPYMNGESSAKSLWAINSTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGAEPLCDNVNTQRVPCSNPRWNEWLLYDMFIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDCF
SSPVKFPDITAIEEHANKVLERELGYNYSHVGPANRIARDNEVRESDKEQLKAISNRDPL
SEITEQEKEFLWSHRHYCLNTPDILPKLLLAVKWNCRDDVAQMYCLLKDWLALRPEQAME
LLDFNYPDRMVRSFAVTCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHSKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMKRPDFMDALQGFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSEMLFHNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRCSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGETYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDNGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGIQECTKTRDFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A096LWV8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia formosa|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFIEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIMSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVHRPVPPV
>A0A8B9TXE0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GLLHTPTKNIFVNVKFQSGGESFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYT
LQVNGKYEYLYGNYPLYQFQMSAKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADER
MKLVVQAGLFHGNEMLCKMVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVI
EKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGT
VQCNPNTESAASLVICFPNVASHPVYYPSFEQVGDMDVKSCISILPTTSYFHQPRSWVLW
GFSELSKPFGLRLSPLYALFCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQ
YPQALAKLLIITKWNKHEDVAQTWPELPVLNALELLDFSFPDRYVGSFITNCSKYLLQLV
QVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGST
HHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCMKQETYLEALSHLQSPLN
PSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIFKNGDDLRQDMLTLQMIQLM
DVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLN
WLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLG
NFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHL
FALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHN
VSKDNRQ
>A0A672ZSE7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
MDREQQIQLSDEEPVVLREENRRRRRKKAITSSSCTSMDQIAVEFVLPTAARGGNSPDTL
QLEVAGNWTVEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQ
TLDCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTQRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVCNGFILVVIHISTASQTIKVSI
DDTPAQVLSSFFTKTANKRVLLGIPENTGEKDFVLRVCGREEYLYGDKPLQNFNWIRQCL
KNGDEIHLVLETPSDPEADLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDC
NRKFRVKVLGIDIPSLPKVPELVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFN
IKIRDLPKGARLNLQVVCGKQVQTPNSKGGSSYPDSPAGGGSHDGKTKSRLLYYVNLLLI
DHRSLLRQGEFILHMWKMPEKSEESSSSSINADKLTSATNPDKASSMAITILLDKYCYPV
VLPKSRDVCRDGGTWGEEAEGGERGQREMPNHLKKQFEAIVATDPLHPLSPEDKELLWHF
RHECMRHPRAYPKLLGSVRWGKQDDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDA
QVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWF
LRSEIAQSMHYQQRYAVLLEAYLRGCGEAMLQDFRKQVEMTEALQKVTREIKAMSADKYD
VTAQVVFQLRQKLETLQLSGLPESFRVPYDPGLRAGTLLIEQCKVMASKKKPLWLQFKRA
DPSTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGM
IEIVKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVA
TYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTS
GKKSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVG
RCEDDAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A7K4RS04|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Columbina picui|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLGWAAWMEYNFPLQLEPMAKALGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLESPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMP
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWRQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYLFHIDFGHFLG
NFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFESRFRGYCEKAYMILRRHGLLFLH
LFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAH
NVSKDNRQ
>A0A3Q1JGU6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETKRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDTEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPID
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMATIEDQANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A7N5ZT03|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQSKYILKVCGCDEYLLEKHPISQYKYIRSCMMLGRLPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHSNWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRYRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNALHQWLKDKNKGEMYDLAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERYCYHHCFQTGLIQWLLF
>A0A8C6W628|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nannospalax galili|TrEMBL
MPPGVDCPMEFWTKEESQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAALRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVERPEDYA
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPAKKPSSVSLWSLEQPFCIELIEGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVICLPEVAP
HPVYFPALEKILELGRHGERGRITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLGALELLDFNFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPHTKEMMHMCMR
QETYMEALSHLQSPLDPSTLLEEVCSVEQCTFMDSKMKPLWIMYSSEEAGSAGSVGIIFK
NGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQL
NKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGY
CERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKF
NEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C6QC23|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nannospalax galili|TrEMBL
MCFSFIMPPAMTDVLDIWAVDSQTAPDGSISVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKIQSLVGLSWIDWLKHTYPPEH
KPSILENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEDE
ASPYDFVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECSKIKKMYEQEMIAI
ESAINRNPSNLPLPLPPKKTRIISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPDNKKPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEI
LDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKL
PPREALELLDFNYPDQYVREYAVSCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSIGHMKVLSKQVEALNKLKT
LNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDS
KMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGC
LATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEF
TLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K6WD34|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Steatornis caripensis|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GALHTPTRNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYVELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAALEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLRTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEEMGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>K7FAB1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pelodiscus sinensis|TrEMBL
MPPGIYCPVEFWSKEGNQNIQVDFLLPTGIYLNLSVSCHASLGTIKQVVWHHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSMRDPEVNDFRAKMRQFCEERAGKRQQLSWRAWLEYSFPLQLEPLTKSPRT
SPLHVSNRSCFINVKFESGEESFTFQISPMEFPITLISYAIKKQATVFRHQRLESSEDYT
LQVKGKWEYIYGNYPLYQFQYIHSCLHQGILPHLTMVHSSSIIAMRDEQTNCTAHTPKMA
AKPPPIPKKKPTHATLWSLDQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQKLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKASSFVVER
FGSLHHDCPLAWVNIMLFDYKDQLKTGECCLHMWSSFPDEKGELLKPMGGTVQSNPNTES
AAALVICFPNVASHPVYYPSFEQSVLVLQLLDLGRSGDYARSTLEDPEEQKQQLMEILER
RNYTELYEHEKDLVWKMRHEIRDQYPEALAKLLIITKWNKHEDVAQMITLLQNWPELPVL
NALELLDFSFPDRYVGSFTINSLKKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRA
LANRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSNYHMGILMKQGEALNKMKALNN
LIKVSSQKATKLQAKEMMHQCMKQETYLEALSNFQCPLNPSIILAEICVDQCTFMDSKMK
PLWIVFNSDEESGAGVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLST
GDKTGLIEVVMRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALEQAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDF
VHVIQQGRTNNSEKFERFRDYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYL
KDSLALGKTDEEALKQFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C7EM85|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neovison vison|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSVLENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDQPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>G3Q661|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gasterosteus aculeatus|TrEMBL
EQNQLSDEEPKILREETRRRRRKKAISSSSCPSMDQISVEFVLPTAARGGSGTEILLLEV
AGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDC
IRYWRAKALKKDVGRIQLVPRPQPADDSLQYQSYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRRIELTDRDAKLYSMDPWVARKPLPEHLLSKVSNAHVLLVIHISTASQTIKVSLQD
TPAQVLASFFAKTANKRVLLGIPQNMCEADFVLRVCGREEYLYGDKPLQDFNWIRQCLKN
GDEIHLVLESPPDTDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTVSMWDCNR
KFRVKVLGIDIPFLPKIPEFIVFIEASIFHGQQLLAQERTCSKNFSEEVLWNCWLEFNIK
IRDLPKGARLNLQVVCGKQPPTANSKGASGKTKSRLLYYVNLLLIDHRSLLRQGEFILHM
WKMPEKSEESSSSINADKLTSATNPDKASAMAVAILLDKYCYPVVLPKSRNLVCRDAGGE
EVEGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGS
VKWGRQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDD
VLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAV
LLEAYLRGCGEDMLQDFRKQVEMTEALQKVTREMKAMSADKCDITAQVVFQLRQKLETLQ
SSGLPESFRVPYDPGLRAGALMIEQCKVMASKKKPLWLQFKRADQTTLSRDPIGIIFKEG
DDLRQDMLILQILLIMESIWETETLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSV
MGSTGAFKDEILSQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMIT
ESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTTGKKSSPHFQKFQDVCVK
AYLALRHHTNLLIILFSMMLMTAGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEI
CREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A3Q3RZY6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSRNDTIKVIKKLVWKNARSEALFT
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTRMRQFCEEKSQERQMLPWQQWMEYSFPCDLEPCCSLPST
KSRNTKKIFINIKFEACDESFMLQQDPQDLPVALMKSALKKKATVFRSVRLEPEDYTLQV
NGSWDFIYGKHPLRQFKYIFSCLRNGQNPHLIMVHRSTISKHQEEQERMCNQVYKSRSQS
RPPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSS
EVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWV
NTMVFDYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFPNIRPH
PLYYPPLEKISDMERNDDTVTATKEEHQKLKEIMDNKNYTEFFEDEKELLWKLRYEVCSL
YPESLSKLLLITKWNKREDVVQMVGLLRNWPDLPAIHALELLDYSFPDPAVRFFTIRCLK
KLSDNELLQYLIQLVQVLKYESYLDCDLTTFLLERALANRRIGHFLFWYLRSEIHVASVS
LRFGLILEAYCRGNIHHIKLLTKQNEALGKMKILSDIVKSGSQKMTVDDLKLCIRQESYL
EALSDLLSPLNPSIILAEICAHKCRFMDSKMKPLWLMYGNPWAQGEMVGIIFKNGDDLRQ
DMLTLQMIQLMENLWKKEGLDLRMSPYGCLSTGNKMGLIEAVKNSDTIANIQRNSSNSAA
TAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRENGQ
LFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKI
LCRNGMLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRES
WKTKVNWMMHSLAKDNRP
>A0A6I9KIG0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysochloris asiatica|TrEMBL
MPPGVDCPMEFWTKEETQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLP
CLSGLHEFDSLRDPEVNDFRTKMRQFCEEAALRRQQLGWEAWLQYSFPLQLEPAARGWGA
GTLRIPNRVLLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVERPEDYT
LQVNGKQEYLYGSYPLCQFQYVCSCLHSGLTPHLTMVHSSSILAMRDEQSNPTSQVQKPR
SKPPPIPVKKPSSLSLWFLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVSVCSGPVWNQRLEFDINICDLPRMARLCLALYAVIEKARKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
HPVYYPALEKILELGRHVEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHQVQE
LFPEALARLLLVTKWNKHEDVAQMIYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPAV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFIKVSSQKTTKPQTKELMHVCMR
QETYLEALSHLQSPLDPSTLLADVCVEQCTFMDSKMKPLWIMYSNEEAGSEGSVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVTKDNRQ
>Q1WIR0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSAQTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGNYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A8KA75|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGLIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K6STE9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Caloenas nicobarica|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTADYYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEVVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEDDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A2K5ZE05|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mandrillus leucophaeus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSSGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEDEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8D0MIU2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKSPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIDML
QKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLPQSFRVPYDPGLKAGALVIEKCK
VMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDL
CLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLSHWLKEKCPIEEKFQ
AAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKER
VPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQL
TSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A3B5PR06|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xiphophorus maculatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRNASGPHSRALYVYPPSVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLTRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEASSKSLWSINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLPYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMNAVEDHANWIISRELGFNFNLSSSRVARDHALTESDSEQMRQLSNRDPLSE
ITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDDVAQMYCLLKEWPSIRPEQAMELL
DCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDSPLARFLLKKALTNQR
IGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQE
KKDETQKVQMKFLVDQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRIMSSAKRPLWLN
WENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSLG
DCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGETYDMAVDLFTRSCA
GYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLI
VISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYI
RKTLALEKTEQVSPDFSVFTSEGTSGNVWTINLTIYIAIKKWPISIYLLEYSLSSDPEPH
SILGDVGRRKSLAQRCPKCGPGPICSSWIDFMRPLNYTNVSQVVDARLFFSIRTHKLKSS
HKNIRYNKVFIF
>G1RC26|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nomascus leucogenys|TrEMBL
MELENYEQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIIIHRSTTSQTIKVSPDDT
PGDILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNR
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A4Z2FBP9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Liparis tanakae|TrEMBL
MDEQQTQASDEEPEVPREDARRRRRRKKAISASSCASMDQITVEFVLPTAARGGSGPDTL
PLEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQ
TLDCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNCLIGYDVTDVSNVHDDELEFTR
RKLLTPRRIELSERDAKLYSMDPWVTRKPLPEHLLTKVSNAHVLFVIHIRMASQTIKVAL
DESPAQVLASFFAKTASKRVLLGIPDGVCEADFVLRVCGREEYLYGDEPLQDFNWIRQCL
KNGEEIHLVLETPPDTDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDC
NRKFRVKVLGIDIPSLPKIPEFIVSIEASIFHGQQLLAQERTSSKSFSEEVLWNCWLEFN
IKIKDLPKGARLNLQVVCGKQPQTPNSKGASAFQDNAAGTGNHDGKAGRHSLSASSSHHP
DTPSERLRLCLRPSGKTKSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPEKSEESSSSIN
ADKLTSATNPDKASAMAVAILLDKYCYPVVLPKSRDAGAARDAAAAGEEAEGGERGQREM
PNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPSGLDVGLAMQLLDCHYSDAQV
RSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLR
SEIAQSMHYQQRYAVLLEAFLRGCGEDMLQDFRKQVEMTEGLQKVTREMKAMSADKCDIT
AQGERGAARPAPPGGRLLWVTARSPG
>A0A8B9WUG7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus grunniens|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASMSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEY
IRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A8B9XL87|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus grunniens|TrEMBL
MGTANPQPGWLCCRIAVLWMVLAGSGKDDWYLRSEKAGCPPGLTAPWNSGPRRRIRAWQL
ISCSPRGLSELPVSRNANLSTIKKVLWHRAQYEPLFHMLSDPEAYVFTCVNQTAEQQELE
DEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHEFDSLQDPEVNDFRGKM
RQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGPGTLRVPNRVLLVNVKFEGSEESF
TFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYTLQVNGKHEYLYGSYPLCQFQYIC
SCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRTKPPPIPMKKPSSVSLWSLEQPF
YIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSVCSEPVWKQRLEFDINICD
LPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGEHCLYMWP
SVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAPHPVYYPSLDKILELGRLGEHGRF
TEEEQLQLREILGGGVPGTVRAREGPSVEDAARDPGALSEALARLLLVTKWNKHEDVAQM
LYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESY
LDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMK
QGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDPSTLLAEV
CVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKNGDDLRQDMLTLQMIQLMDILWKQE
GLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNP
GEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFG
INRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAA
GLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A850VW52|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fregata magnificens|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVKDPEVNDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A091ILR7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calypte anna|TrEMBL
STMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPSLPVLRLVAREGDRAKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWSAWMEYNFPLQLEPMAKRL
GTGPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVESPED
YTLQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQNNCIASPPK
MAHKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRMDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQVGDVDTFLGRHRNPPSFAGQEHSKLQLKEILERRSHTELYEHEKDLVW
KMRYDIRDQYPQALAKLLIITKWNRHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYV
GSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKLLLDRALSNRKIGHFLFWHLR
SEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTK
EMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGG
VGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDT
IANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGD
RHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKF
ERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALK
HFRLKFNEALRESWKTKVNWLAHNVSKDNR
>A0A093PYA7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Manacus vitellinus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMAVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVHNIFWCVCCLVYIHILVLQNLQ
PLTISDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQI
QCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRSCAGYCVATFILGIGDRHNSN
IMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERF
QEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFM
KQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C5ZXV9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Marmota marmota marmota|TrEMBL
MPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSKI
GVLIGKDVFSFQVSPEMNPIKINELAIQKRLTIHGKEDEASPYDYVLQVSGRVEYVFGDH
PLIQFQYIRNCVMNRTLPHFILVECSKIKKMYEQEMIAIEAAINRNSSNLPLPLPPKKTR
VISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCKTIVSSEISGKNDHIW
NELLEFDINICDLPRMARLCLAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWV
NTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIKFPENKKQ
PYYYPPFDKIIEKAAEIASSDSANVASRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTL
RQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLSPRDALELLDFNYPDQYVRE
YAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSE
VHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEA
MHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVG
VIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIA
DIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRH
SDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGR
FRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQF
KQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K6DEG7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Origma solitaria|TrEMBL
MELEDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHVFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVISQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQEVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3B3SA48|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Paramormyrops kingsleyae|TrEMBL
QALWKEAQRHPLFSFLGDMESHMFECVNQSAVHEELEDETQRLCDVRPFLPVLRLVPRNC
GRAERLDSKIGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQMMTWMEWLESCF
SPQVEVGAIDGLQEKLFEGALKVTMHFSQSQDTASLKVSPAITPRELREQALRKWLTTHS
SSEEVQEEVRWDDYVLRISGKLEFLTGEHSLIHFKYIRTCVMATESPHLTVVHCSAIQSM
FEKEITAIGAVVNRKTSNPPVPLPPKRRGPSMHTCVWDIHTPFRITLVKGAKVNAEETTK
VQVRAGLFHGTELLCKPAVSSETSGRSEHTWGQSLDFDINVGDLPRMARLCFAIYAVMDK
VKKQKSTKSPHINKYQTIRKAGKVHYPIAWVNTMVFDYRGHLKTGEVVLHCWSSFPDELE
EMLNPIGTIQTNPYTENATALHVQFPEYHAYPIVFPAFDKILEKAAEIARGSDCMPMGRG
GKKFHSELKEIMERDPLSQLYENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQ
LQALLQIWPKLSPRDALELLDFNYPDQYVREYAVRCLCDMSDDELSQYLLQLVQVLRYEP
YYDCALSRFLLERAQANRSIGHFLFWHLRLVLRVSGVGVAGVEALNKLKAVNELIKLGTI
KNVRKAKEAMLSKEAMLTCLRQTGYAETLSDLQSPLNPQVLLSGISVEKCRYMDSKMKPL
WIVYNNKLLDGDTLGIIYKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGD
RSGLIEVVSAAETIANIQLTNSNVAAAAAFNKDALLNWLKEKNSGDALDRAIEEFTLSCA
GYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIH
VIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAHTWS
>A0A674BY56|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPGEYGMLGEWKKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRPFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPMILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTIVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKQNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKV
VTSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCP
LAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFPN
IRPHPLYYPHFDKLRDLEKNGGKVIATKVEHMKLKEIVDNKNYTEFFEDEKELLWKLRGV
VRERYPESLSKLLLITKWNKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTI
RCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLKSEMHV
SSVSLRFGLILEAYCRGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKL
CIKQEAYMEALSYLLSPLNPSIKLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIF
KNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQ
RNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDN
IMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRE
CCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVK
FNEALRESWKTKVNWMMHSLAKDSRL
>A0A667XEK0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MDQQQVQVSDEEPVVLREESRRRRRKKAITPSSCASMDQITVEFVLPSAARGGSGPDTLL
LEVAANWTVEQVKAQVWLRAVASNLCPDFYQRFSPDHCILLYQKKGSVCEIYDKHQVFQT
LDCIRYWRALKKEVGRIQLVPRPQPTDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDAKLYSTDPWLTDRPLTEHLLSKVSNGHILLVIHVGSNSQTIKVSID
DTPAQVLASFFTKTANKKALLGIPDSVCEADFVLRVCGREEYLYGDKPVQNFHWIRQCLK
NGEEIHLVLETPPDPALDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKNPELTVFVEASIFHGQQLLAQERTTSKPLSEEVLWNCWLEFNI
RIRDLPKGARLNLQVTAQKTQRELFSEVEEATKSRLLYYVNLLLVDHRSLLRQGEFILHM
WKMPEKSEESSSSVNADKLTSATNPDKASSMAVSVLLDRYCFPVVLPKSREAGRDAAAPD
EAEGGERGQREMPNHLRKQFEAIVATDPLHPLSPEDKELLWHFRHECMRHPRAYPKLLSS
VRWGKQEDVLITHRLLERSTAWDSSRLDVGLAMQLLDCHYSDAQVRSMAVRKLETLGDDD
VLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIVQSMHYQQRYAV
LLEAYLRGCGEAMLQDFRKQVEVTEALQRVTREIKAMSADKYDVSAQVVFQLRQKLETLQ
SSGLPDSFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSRDAIGIIFKDG
DDLRQDMLILQILLIMESIWETENLDLSLLPYGCISTGNRIGMIEIVKDATTIANIQQSV
VGSTGAFKDEILHQWLRDRCVSEDKKLCCVCVCVCVCVCVCVCVCVCVCAGNLFHIDFGH
ILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFHKFQDVCVKAYLALRHHTNLL
IILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQINWF
VHLVLGIKQGVEKRSA
>A0A674C040|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
ITSSVGDVSVHFKWCCFLLYDADAYVFTCINSTAEREELEDETRRLCDVRPFMSVLRLVA
REGDRVEKLTNTQISLLIGKGLHEFDSQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWM
EYSFSCDLEPCVSLAEPGGIKTKGTKKIFVNVKFEASDVSALFLWPFLLLFLMFVLVNQS
VTFLRQEKPEDYTLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTIVKYQE
EQGCLGSQVSKSRSLSKPPPLPVKKVRGQPLGTTLVVQAGLFHGSELLCKVVTSGEVNVC
SEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPLAWVNTMVF
DYKDQLKTGEFLLSTWPSVPGDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPHFD
KVHLILKKWREGYSHQGGGKGLSILKEIVDNKNYTEFFEDEKELLWKLRGVVRERYPESL
SKLLLITKWNKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLRDE
ELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLKSEMHVSSVSLRFGL
ILEAYCRGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYME
ALSYLLSPLNPSIKLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIFKNGDDLRQD
MLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAAT
AAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQL
FHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKIL
CRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESW
KTKVNWMMHSLAKDSRL
>A0A674BY72|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPGEYGMLGEWKKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRPFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPMILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTIVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVV
TSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPHFDKVHLILHTRFNSRHCTFHMKLKEIVDNKNYTEFFEDEKELLWKLRGVVR
ERYPESLSKLLLITKWNKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTIRC
LRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLKSEMHVSS
VSLRFGLILEAYCRGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCI
KQEAYMEALSYLLSPLNPSIKLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIFKN
GDDLRQDMLTLQMIQLMEILWKKEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHN
DNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERF
RECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFK
VKFNEALRESWKTKVNWMMHSLAKDSRL
>A0A8C0J0V2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelonoidis abingdonii|TrEMBL
MELGNYEQPVVMREEAKRRRRRMKPHSPASNLSSMELISIEFILPTSNKQVQETMLLEIA
GNCTVEQMKAQIWMRAIEMSQITDFYHKFTPDQFILQYQKKGQWYEIYDKHQVIQTLDCI
LYWKVLQKKVGKISVIQKQKPAQAVQEFQTQLNDLIGYDVTDVSNVHDDELEFTRRRLVT
PRMIEVACRDPKLYSMHPWITSKPLPEYVLKKITNNNIFIIIHRGTTSQKIKVSIDDTPD
MILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNGEE
IHLVLDDPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRKFR
VKIVGIDIPVLPRNTELTVFVEANIQHGQQLLSQRRTISKPFTEEVLWNTWVEFDIKIKD
LPKGALLNLQIYCGKAQALSTKVNLQSHDSPNSDSKCKTQLLYYVNILLIDHRSLLRSGE
YVLHMWKISGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSDPQ
GDRTRAEMPNQLRKQLEAIIDTDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWG
QQEIVAKTYQLLAKREAWDHSSLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVLHY
LLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEA
YLRGCGKAMLHDFMKQVQIIKLLHKVTMDIKSVSAEKYDVTSQVITQLKQKLEKLQNSKL
PESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLR
QDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNT
GAFKDEILNQWLKDRCVIEEKFQAAVERFVYSCSGYCVATFVLGIGDRHNDNIMITESGN
LFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTTGKKTSLHFSKFQDICVKAYLA
LRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKHFLDQIEVCRDKG
WTVQFNWFLHLVLGIKQGVEKHSA
>A0A226MYY4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callipepla squamata|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMLLLE
IAGNCTVEQMKAQIWMRAMEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNVWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQGVPILHPSAGGIMLSPTWFIPNRSSYAAVKFEPYHDSALARFLLKRGLRNKR
IGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIK
SVSAEKYDVTSQVIAQLRQKLEKLQGSKLPESFRVPYDPGLRAGALVIEKCKVMASKKKP
LWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQFQAAVERFVYSCAGYCVATFVLGI
GDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSL
HFHKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDA
KKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>G1NY61|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myotis lucifugus|TrEMBL
MELESNEQPVVLREDNRRRRRRMKPRGSAASLSSMELIPIEFVLPTSQRTSKTPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYQRLSPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRRGPSEETLAFQRQLTALMGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPQLYAMHPWVTSKPLPEYLLKKIAHNCIFIVIHRSTTSQTIKVSADDT
PAAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRHCLKNG
EEIHLVLDAPPDPAQDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHDSVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIRI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPEARGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKDSSMSICILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEMVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLNYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVVEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWEIESLDLCLLPYGCISTGDKIGMIQIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQEVCTKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7L1HX23|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nycticryphes semicollaris|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFLLPTSNKNTKVPEMVLLE
IAGNCTVEQMKAQIWMRAIETSQTADFYHTFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQQFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDDPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIGTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6J0I2U5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lepidothrix coronata|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSTLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTTVSTEISGRSDHVWNEELEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVVNVSDELEEMLNPMGTVQTNPYTENATALHIRFQEYSKQPINYPPFDKILE
KAAEIARNSDNAAMAGRGGKKFYVVLKEIMERDPLSQLCENEMDLIWTLRYDCRENFPQS
LPKLLLSLKWNKLEDVAQLQALLQIWPKLLPREALELLDFNYPDQYVREYAVGCLKQMSD
EELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQMLFWHLRSEVHIPAVSVQFG
LILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYR
EALSDLQSPLNPSVILSELHVEKCRYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQ
DMLTLQILRLMDILWKEAGLDLRILPYGCLATGDHSGLIEAVSSSETIADIQLNSSNVAA
AAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQ
LFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLI
LRKHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRES
WTTKVNWMAHTVRKDYRS
>A0A8C9AXI3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phocoena sinus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K7GVI7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Erithacus rubecula|TrEMBL
MELRDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEILLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNADLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRT
GDYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQEAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A663LSD7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Athene cunicularia|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCISSPPRMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFENSLALVEEHTLQLREILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKL
LIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHELF
QYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILE
AYCRGSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHVCMKQETYLEALS
HLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLT
LQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAF
NKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHI
DFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRH
GLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTK
VNWLAHNVSKDNRQ
>A0A8C9E664|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phocoena sinus|TrEMBL
MPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKQTYPPEHEPSIPE
NLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDEVSPYDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAIEAAINR
NSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TVVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKAINPSKYQ
TIRKSGKVDYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALA
NRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLKTLNSLI
KLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYIEKCKYMDSKMKPL
WLVYNNKVFDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDHSGLIEVVSTSET
IADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGD
RHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKF
GRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALK
QFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C5NN11|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Junco hyemalis|TrEMBL
FLSRMPPGIYCPTEFWSKGENQSIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYE
PLFHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQ
ISLLIGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAK
GLSSLQIPNKNIFVNIRFQSGGVNFMFQISPWEFPITLMSYAIKKQATVLRPETVQQPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPK
AASKPPPLPKKKVRGDRDPWAPLAQAVPRAHGAVLAVPQLVVQAGLFHGTEMLCKTVSSS
EVSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWA
NVMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAH
PVYYPSFDPECALAVQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLI
ITKWNRHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGRALSISAQGCVSCFLSVL
RDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPAVSLR
FGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCMKQET
YREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKNGDDL
RQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNM
VATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRET
GQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCERAY
MILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFNEALR
ESWKTKVNWLAHNVSKDNRQ
>A0A8C5IZJ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Junco hyemalis|TrEMBL
IAFRFLFSLHSLDVLEINCSIVPRDSIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHA
QYEPLFHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLI
NSQISLLIGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEP
AAKGLSSLQIPNKNIFVNIRFHFMFQISPWEFPITLMSYAIKKQATVLRPETVQQPEDYT
LQVNGKCEYLYGNYPLYQFQVSLREFITECLSELGMRQERDTLSRESCPVPFPCSAQAVP
RAHGAVLAVPQLVVQAGLFHGTEMLCKTVSSSEVSVCSEPVWRQRLEFDISVRDLPRMAR
LCLALYAVVEKARKARSTKKKSKKADCPIAWANVMLFDYRDQLKTGECCLHMWSSFPDEK
GELLNPMGTVQCNPNTESAAALVICFPSVAAHPVYYPSFDPECALAVQKLQLKEILERRS
HTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNRHEDVAQMISLLQTWPELPVLNA
LELLDFSFPDRYVGCVSCFLSVLRDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSN
RKIGHFLFWHLRSEMHVPAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVK
VSSQKATKPQTKEMMHMCMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLW
IVFNSEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDK
TGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAG
YCVATYVLGIGDRHSDNIMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHV
IQQGKTNNNEKFERFRGYCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDS
LALGKTDEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C5JAN7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Junco hyemalis|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQVWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIVIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKYKTQLLYYVNLLLIDHRFLLRC
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C6NG44|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Melopsittacus undulatus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GPFHIPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKTA
AKPPPLPKKKPNYGSLWSLEQSFYIQLVQGSKVNADEGMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWQQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQVRNITEEMRTLSCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAVNS
LKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPA
VALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMMHVCM
KQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMQSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
EKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFN
EALRESWKTKVNWLAHNVSKNNRQ
>A0A3B3WMX3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia mexicana|TrEMBL
MPPGKYGTQEEWEQDGDREIYMDFLLPTGIFLKFPVSRNDTIRNIKKMVWKNASREPLFF
GLGDPDLYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRSEKLTNAQISLL
IGKGLHEFEAQKNHEVDEFRTKMRTFCEEKSLERQNLPWQRWMEYSFPCELEPCSSPATG
GSSKSKHGKKLFVNIKFESSDESFMLQQDSQDLPVALMKSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGQHPLCQFKYIFFCMRNGQNPQLTMVHHSTISKYQEDQGRVCSQMYKTR
SLSRPPPLPLKKQNTSSLWSIHEPFYIHLVHGSKVNADEGMKLVVQAGLFHGSELLCKMM
TSSEVTVCSEPLWDQRLEFDINVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGDFLLSMWPSVPDDKSDLLNPMGTVQKNPNVDSAAGLLIRFPNI
RPHPLYYPPLEKTIDPEMNGNTDFPSKDEYLKLKEIMDNKNYTEFFEDEKELLWKLRIEV
RDYFPECLSKLLLITKWNKREDVVQMVSLLKSWPELPAIQALELLDYSFPDPAVRYFTIR
CLKKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLKSEIHVA
SVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDIVKTGSQKMTVDDLKLCIRQE
SYLEALSDLLSPLNPSVILFEICADKCRFMDSKMKPLWLMYKNPLEQADMVGIIFKNGDD
LRQDMLTLQMIRLMENLWKKEGLDLRMIPYGCLSTGNKTGLIEIVKSSDTIANIQRNSSN
SAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEKA
YKILCRNGTLFVNLFAMMKAAGLPELSSSKDIQYLKDSLALGKSEDEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A671F1Q2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinolophus ferrumequinum|TrEMBL
MPPGVDCPMEFWTKEENQTVAVDFLLPTGVYLNFSVSRNANLSTIKKVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLSWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQPSSMSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHG
NETLCKTVSSSEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKK
SKKADCPIAWANLTLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAA
LIICLPEVAPYPVYYPALDKILELGRHGEHCRFTEEEQLQLREILERRGSGELYEHEKDL
VWKMRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDSSFPDR
HVGSFAIKSLRKLTDDEVFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWH
LRSEMHVPSVALRFGLIMEAYCRGSIHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPH
TKELMHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYNNEEAGS
DGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLH
SDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLG
IGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNS
EKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEE
ALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6J2HKS5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pipra filicauda|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKIINNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYIIGETPVKDFHWIRQCLKNG
EEIHLVLDDPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPILPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDTKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDICVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C7Z4R8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias sinensis|TrEMBL
MPPAMTDLVDIWAAHSPLDGQAPVHVTMDFLLPTGIYIQMEVPREATIQHIKLLLWKQAK
SFPLSSFLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVFRLVTRNCGRAERLLD
SKIGVIIGKGLHELDGINDQEVKDFRSKMQRLSEERMHRVQMMSFTEWLQACFSPQLEPS
AGTAIADGANDWPADLKVIIHFDQSQDSTSLKVPSSCTPSVLIEIALKKWQTTHAPEEET
NKDKHILRVSQCLDFLCGDHPLIQYKYIRSCLQAKESPHLTLVHINAVKAIFDKENAAIG
AVVSRKSSNPPLPLPPKKRAPTVQVRAGLFHGTELLCKPAVSSESSGRSNHSLENNTLEF
EISVCDLPRMTRLCFAIYAIMEKVKKKSYKNPHINKYQTIRKAGKVHYPIAWVNTMVFDY
KGQLKTGDMILHCWSSFPDELEEMLNPIGTVRINPYPENATALHIHFPDYGPHPIVFPPF
DKILEKAAEIAGSSDSTPIGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRLDCREN
FPQSLPKLLLSVKWSKHEDMAQVSLVIDCFKPSAPDTFVLQGKCFHWKRISDYYYYGFLM
FNDEIIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNS
GDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFG
IKRERVPFILTHDFIHVIQQGKTGYTEKFGRCVPLFHSCGSHVPIQVQDSLALGTTQKPA
SPVQVHVTPYRCM
>A0A8C8DC91|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias sinensis|TrEMBL
MDRQSIQVSDEEPEVPREECRRRRRKKAITSSSCVSMDQITIEFVMPSAARGGSGPDILT
LDVAGNWTVEQVKAQVWMKAVTLNLCPDFYQRLSPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIPYWRGTAKGVGRIQMVTRPQLSEESLQYQRYLNGLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLAKVNNGHILVVIHIGTVSQTIKVSIN
DTPSQVLASFFAKTSNKRVLLGIPDDVCEADFVLRVCGREEFLYGEKPLQNFNWIRQCLK
NGEEIHLLLEKPPDPELDVVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPTLPKVPELVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVNSSLQSPSAGKTKNRLLFYVNLLLVDHRSLLRQGEFILHMWKMPE
KSDESSSSINADKLTSATNPDKSSSMAVAILLDKYCYPVVLPKSRDVGRDSGAGEEMEGG
ERGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRQECMRDPRAYPKLLGSVKWGK
QEDVLATHRLLERSNAWDTSGLDVGLAMQLLDCHYSDSHVRSMAVRKLETLEDDDVLRYL
LQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAY
LRGCGESMLQDFRKQVTDMTMALQKVTREIKAIAADKYDVSAQVVFQLRQKLETLQSSGL
PETFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLR
QDMLILQILLIMESIWETECLDLCLLPYGCISTGNKIGMIEIVKDATTIANIQQRVVGST
GAFKDEILHQWLRDKCVSEDKFQQAVERFLLSCGGYCVATYVLGIGDRHNDNIMITESGN
LFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFLKFQDVCVKAYLA
LRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEEEAQRHLLDQIEICREKG
WMVQVNWFVHLVLGIKQGVEKRST
>A0A8C0CBQ6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balaenoptera musculus|TrEMBL
MCFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDCVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRALPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKAI
NPSKYQTIRKSGKVDYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIRFPENKKQPYYYPPFDKSRGGKKFLAVLKEILDRDPLSQLCENEMDL
IWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQ
YVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWH
LRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVDALNKLKTLNSLIKLNAMKLNRAK
GKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYIEKCKYMDSKMKPLWLVYNNKVFGE
DSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDHSGLIEVVSTS
ETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGI
GDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTE
KFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEA
LKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A091KNU3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Colius striatus|TrEMBL
SRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRSKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGL
GAGFLHPPTKNIFVNVKFQSGGESFTFLISPKEFPITLMSYAIKKQATVFRHETVENPED
YTLQVNGKCEYLYGNYPLCQFQYIRSCLHRGLTPHLTMVHCSSIIAMRDEQSNCIASPPK
MLAKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQVRDRDTFRGRHSHCTALLVQEHRVIKLQLKEILERRSHTELYEHEKDL
VWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDR
YVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWH
LRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQ
TKEMMHVCMKQETYLEALSHLQSPLNPNTILAEVCVDQCTFMDSKMKPLWIVFNNEETGG
GGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHS
DTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGEALDQAIEEFTLSCAGYCVATYVLGI
GDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNE
KFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEA
LKHFRLKFNEALRESWKTKVNWLAHNVSKDNR
>A0A3B5KFU5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
MPPGKYGMQEEWEKEGDQRIVMDFLLPTGIFLKFPVSRNDTIRTIKKMVWKNAQSEALYA
ALGDPDSYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVARVGDRVEKLTNTQISQL
TGKGLHEFEAQKNHEVDEFRAKMRTFCEEKAQERQVLPWLQWMECNFPCELEPCSSPVEC
GGVKSKNTKIFINVKFEASDESFMLQQDPQDLPAALMRAALKKKATVFRSVRQEPEDYTL
QVNGRWEYIYGRHPLSQFKYIFSCLRNSQNPHLTMVHHSTIRKYQEEQGRACSQAYKCHR
PSRPPPLPLKKQNTSSLWSINEPFHIRLLHGSRVNAAEGMKLVVQAGLFHGSELLCKMVT
STEVAVCSEPVWDQKLEFDINFSDLPRMSRLCFALYAVIEKNKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIQFPNVR
PHPLYYPPLEKISDLEKNGFAVVATKVEHIKLKEIMDNKNYTEIFEDEKELLWKLRSVVC
DHYPESLSKLLLITKWNKREDVVQMVGLLRYWSDLPAIHALELLDYSFPDPAVRAFTIRC
LRKLSDEELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNSRIGHFLFWHLKSEIHVPS
VSLRFSLILEAYCRGNIWHIKLLIKQNEALLKMKTLSDIVKSGSQKMTVDDLKLCIKQES
YLETLSDLLSPLNPSVVLAEICADKCRFMDSKMKPLWLMYKSPWAQGDMMGIIFKNGDDL
RQDMLTLQMIRLMEILWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNS
AATAAFNKDALLNWLKSKNPEGKLEKAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRET
GQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAY
KILCRNGMLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKVNWMMHSLAKDNRP
>A0A8C5C9I3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MDPHTICAASGEEDCGALSRTRRRRKGITSASLSAMDQITIEFILPTTPKNGLSPHTTLL
EVPGNWTVEQVKAQVWLRAVASNFSPDFYHKFSPDHCILLYMKKGTLCEIYDKHQVFQTL
DCIRYWRALKKDVGRISLVFRPPQQDEALRYQRFLNQLIGYDVTDVSNVHDDELEFTRRK
LLTPRRNELQERDPRLYAVDPWLTDRPLRDHLLSKVMNGHLLVVIHIFTTSQTIKVSIDS
TPEQVLASVFAKTANKRALVGIPDDVCESDFVLRVCGREEYLYGDRPLQDFSWIRRCLKN
GEEIHLVLEKLPDTDLDQVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNR
KFRVKVLGIDIPLLPRNPDLTVYIEASIFHGQQLLAQERTTSKPFMEEVLWNTWLEFDIK
IRDLPKGARLNLQVSCGKTAPPTTSKGSSYQDSPGAGSTAEGKSKTRLQYYVNLLLVDHR
SLLRQGEFVLHMWKIPEKGEESSSSVNADKLTSATNPDKASSMAVAVSLDKYCYPVVLPK
SRDSGGAGGGASVGGGGASVGGGASSGGCGDSGGEDSGEPGGERGQREMPNHLRKQFEAI
LAKDPLHPLSPEDKELLWHFRHECMRHPRAYPKLLASVRWGRQEDVQAAHAMLERSSAWD
SSGLDVGLALQMLDCNYSDAQVRSMAVRKLETLGGDDVLRYLLQLVQAVKFEPYHDSALV
RFLLKRALRSKRIGHFLFWFLRSEIVQSLHYQQRYAVLLEAYLRGCGDAMLTDFHKQVEV
TEALQKVTREMKAMLADKYDVSSQVVFQLRQTLEALQSSGLPQTFRVPYDPGLRAGTLMI
EQCKVMASKKRPLWLQFKRADPSSLSSDPIGIIFKDGDDLRQDMLILQILLIMESIWETE
SLDLYLLPYGCISTGNRIGMIEIVKDAATIANIQQSVVGSRGAFKDEILNQWLRDKCVNE
DRFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGI
SKEWVPFVLTPDFLYVMGTAGKKSSPHFQKFQDVCVKAYLALRHHTNQLIILFSMMLMTG
MPQLTSKEDIDYIREALTVGRSEEEAERHLLEQIEICREKGWMVQINWFVHLVLGIKQGV
EKRST
>A0A1A7YF43|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Iconisemion striatum|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREAALNTIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDSTGPHSRALYVYPPNVESTQELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYTQLPTD
SFVMPSYSRRISTATSYMNGEAASKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSVCSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPEMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNFPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEGYDRAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQTFDDIA
YLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A851T522|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothocercus nigrocapillus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSGNLSSMELISIEFILPTSLKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIVGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PPGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSALDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFVKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITEA
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSVHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C2C168|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSPELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYADYVALRISVCLFLDNFTMPSYARRISTAT
PYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGIYHGGEQLCDNVNTQR
VPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHT
LVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSSPVKFPDMATIEDH
ANWIISREMGYNYCQSGQKHLCHSPRHLMNFLWRHRQYCVNIPEILPKILLAVKWNSRDE
VAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVL
KYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYL
KHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAH
QLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRI
MENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQ
WLKDKNRGEMYDMAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLD
HKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLF
INLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWI
FHTIRHHAQN
>A0A1A8QS60|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius rachovii|TrEMBL
LLPTGIFLKFPVPRNDTIKNIKKMVWRNAKTEALYFGLGDPEGYVFTCINDTAEREELEE
ESRRISDVRPFMCVLRLVAREGDRGEKLTNSHISSLIGKGLHEFEAQKNHEVDEFRSKMR
TFCEEKALERHNLPWQQWMEYSFPCDLEPCCSPPVHGGTKSKHTKKLFINVKFEACDESF
MLQQDPLDIPVALMKSALKKRATVFRSVRQEPEDYTLQVSGRWEFIYGDHPLGQFKYIFS
CLRNGQNPQLIMVHHSTISKYQEEQGQLCSQV
>A0A670HY80|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podarcis muralis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNIESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWAINSNLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLQYEMHVLDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKSNRLARDNELRD
CDKEQLRSICTRDPLSEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYC
LIKDWPPIKPEQAMELLDCNYPDPMVRAFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYL
DNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQ
VEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLR
LEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQ
NQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKN
KGEMYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKF
GYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMM
LGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQH
ALN
>A0A7K9S0A0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sterrhoptilus dennistouni|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWQQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGPGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPLTLMSYAIKKQATVFRHETLQKAEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKAP
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMPCKTVSS
SEVAVCSEPVWRQRLDFDIGICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7J7WDW6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pipistrellus kuhlii|TrEMBL
MCFNFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISTIKQMLW
TQINNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
ESSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHWKEDE
VSPYDYVLQISGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHGT
ELLCKTIVSSEISGKNDHVWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTIN
ASKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQT
NPYTENATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEI
LDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKL
PPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQFLFWHLRSEVHIPAISIQFGVILEAYCRGSVGHMKVLSKQVEALNKLKT
LNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDS
KMKPLWLVYNNKIFGEDSVGVIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGC
LATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEF
TLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K7N8K1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Haliaeetus albicilla|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGQTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAF
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALSKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8D0ABC1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MDGQQIPVSDQEPKALREDTRRRRRKKAIMSSSCTSMDQISVEFVLPTAARGGNNPDTLL
LEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLAPRPQPSDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIQLADRDAKLYSMDPWVTRKPLPEHLLSKISNGHILVVIHIGTASQTIKVSID
NTPAQVLVSFLAKTANKRSLLGIPDNMCEADFVLRVCGREEYLYGDKPLQDFNWIRQCLK
NGEEIHLVLEAPPDTDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVVCGKQSQTPNSKGSSAYQDNAAGTGSHDGKIKSRLLYYVNLLLID
HRSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASAMAVAILLDKYCYPVVL
PKSRDVGRDAATGCEEAEGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRH
ECMRDPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQV
RSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKTALRSKRIGHFLFWFLR
SEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTREVKAMSADKCDIT
AQVVFQLRQKLETLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADP
TTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIE
TVKDATTIANIQQSVVGSTGAFKDEILCQWLRDKCVSEDKFQQAVERFLYSCGGYCVATY
VLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGK
KSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRS
EDEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A8D0DBG3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MQQSDQEPKALREDTRRRRRKKAIMSSSCTSMDQISVEFVLPTAARGGNNPDTLLLEVAG
NWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDCIR
YWRALKKDVGRIQLAPRPQPSDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTP
RRIQLADRDAKLYSMDPWVTRKPLPEHLLSKISNGHILVVIHIGTASQTIKVSIDNTPAQ
VLVSFLAKTANKRSLLGIPDNMCEADFVLRVCGRYVGVIHWICLKNGEEIHLVLEAPPDT
DLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVLGIDIPSL
PKIPEFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLEFNIKIKDLPKGARLNLQV
VCGKQSQTPNSKGSSIKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEESSSSINA
DKLTSATNPDKASAMAVAILLDKYCYPVVLPKSRDVGRDAATGCEEAEGGERGQREMPNH
LKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRWGKQEDVLATHRL
LERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFE
PYHDSALVRFLLKTALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQ
DFRKQVEMTEALQKVTREVKAMSADKCDITAQVVFQLRQKLETLQSSGLPESFRVPYDPG
LRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQDMLILQILLI
MESIWETESLDLCLLPYGCISTGNKIGMIETVKDATTIANIQQSVVGSTGAFKDEILCQW
LRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILG
NYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTNLLIIL
FSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQINWFVHL
VLGIKQGVEKRST
>A0A3P9CFA7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Maylandia zebra|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDSEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQQHILYVVAVGVYTYKGTILVLLYSSDMIYVNI
SSGSYLDCSSKTERKIALLLFCMPSVHLEHLIANSSI
>A0A3S2PEJ6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias javanicus|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDFEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYSQLPTD
SCHAVILGGLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQMCDNVNTQRVPCSNPRWN
EWLNYDMYILDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTHTLVANKMALN
LWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEHFSSPVKYPDMNAVEEHANWTISREL
GFNYNISGQSNRVARDHALTDSDSEQLKQLSNRDPLSEITEQEKDFLWRHRHYCMNIPEI
LPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAMELLDCNYPDPMVRHFAVRCLDKFLT
DDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRF
GLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMRFLVEQMKRPDY
MDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSEMLFQNNEIIFKNG
DDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRSSHTIMQIQCKG
GLKGALQFNSNTLHQWLKDKNRGEMYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVK
DDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECTKTKEFERFQEMC
YKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKGEQEALDYFMKQMN
DAHHGGWTTKMDWIFHTIRQHALN
>A0A3S2PE47|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias javanicus|TrEMBL
MPPAMTDLVDIWGAHSPLDGQAPVHVTMDFLLPTGIYIQMEVPREATIQHIKLLLWKQAK
SYPLSSFLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVFRLVTRNCGRAERLLD
SKIGVIIGKGLHELDGINDQEVKDFRSKMQRLSEERMQRVQMMPFTEWLQACFSPQLEPA
AGTAITDGANDWPADLKVIIHFDQSQDSTSLKVLSSCTPFVLIEIALRKWQTTHAPEEET
KKDQYILRVSQCLEFLYGDHPLIQYKYIRSCLQTKESPHLTLVHINTVKAIFDKESSAIG
AVVSRKSSNPPLPLPPKKRAPTQVQTCVWDVSSPFKVVLVKGSTVNADENAKVQVRAGLF
HGTELLCKPAVSSESSGRSNHSLENNTLEFEISVCDLPRMTRLCFAIYAIMEKVKKKSYK
NPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDMILHCWSSFPDELEEMLNPIGT
VRTNPYPENATALHIHFPEYSPHPIIFPPFDKILEKAAEIAGSSDSTPIGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVSCLRDMSDEELLQYLLQLVQVLRYEPYYDCALTH
FLLERAQRNRKIGHFLFWHLRSEIHMPAVSIQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNTRSKTKEAMLTKEAMITCLKQSGYSEALSDLHSPLNPNVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLMSSDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRVVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGNTEKFGSFRLYCEKAYLVLRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKSDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A6P7HGG4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Parambassis ranga|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLINIKQQLFTEARKYPLYH
LLQVIEPLGNREEKILNREIGFAIGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGG
GAHSQALYVYPPNVESSPQLPQHIYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVNHDSLP
EQLIAESIRKKSRSMHLSPQQLRLCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCI
TVGRLPHLMLVSKDSLYSQLPGSGFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLR
VRLLCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLAD
LPRSARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYKDILVSGKVALSLWPVPHGLEDL
LNPIGVAGSNPNKETPCVELEFSWFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSR
LACDSSVSAGDAEQLRSLCSRDPLYELSEQEKDFLWRHRHYCVNMPESLPKLLLSVKWNS
RDEVSQMYCLLKEWPLMEPESALELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLV
QVLKYEMYLDNPLARFLIKKSLTNQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACG
MYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLN
PVHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQI
IRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNT
LHHWLKDKNRGEAYDRAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGH
FLDHKKKKFGYKRERVPFVLTQDFLIVISKGIQESTKTKEFERFQEMCYKAYLAIRQHAS
LFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMD
WIFHTIRHMPNEH
>A0A7K8SM10|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nyctibius bracteatus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKALGT
GPLQTTTKNIFVNVKFQSGGESFTFQISPKEFPVTLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGQTPHLTMVHSSTIMAMRDEQTNCIASPPKMV
AKPPPLPKKKPNYGSLWSLEHPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPPFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A4W3JS86|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPAMTDPLDIWAVDSQIPADNSITVDFLLPTGIYIQLDVPREATIDQIKMLLWRQAQTY
PLYTVLGEKDSYMFQCVNQSAVHEELEDESRRLCDVRPFLPVLKLVARNCNRSERLLDSK
IGVLIGKGLHEFDALTDPEVREFRSKMRMFNEEKMLKLQGLSWMDWLKHSFPPELESTAF
NNFEDKLPKENLVVAVQFDSCQVRHENFSFQISPNLNPLDLNELAIRKQLTIHGKENEEF
NPRDFVLRVSGKQEYLFGEQPLIQFRYIRNCVLKGSNPQLTLVDCCTIKEMCDREMSAIG
VALHRKISNAPLPLPPKRRTISVSTQSLRTSLLYSTTSCYMCDVAKPYCIVQVRAGIFHG
TELLSKSVVSTEVSGKNDLVWNEILDFEINLCDLPRMSRLCFAVYGVMDKVKKQKSTKNA
SKYQTIRKHYPIAWVNTMVFDFRAQLKSGDLDLHCWSSFPDEMEDMLNPMGTVQTNPYSE
NAASLHIQFQEYSKSVIYYPAFDKVSCHSETVPTPSLKEIMERDPLSQLCENEMDLIWTL
RYDCRENFPQSLPKLLLSVKWSKHEDVAQLQALLQIWIKLCPRDALELLDFNYPDQYVRE
YAVKCLKEMSDEELSQYLLQLVQVLKYEPYFDCALSRFLLERAQANRRIGHFLFWHLRSE
MHLPATSLQFGLILESYCRGSFTHIKELSKQMEALSKLKAINNLVKLSYLKVTRTKVKEV
MNTCLKQPVYTEALSDLQSPLNPSVILSKLNVDKCKFMDSKMKPLWILYNNKMSGGEPVG
IIFKNGDDLRQDMLALQILRLMDMLWKEAGLDLRIVPYGCLATGDKSGLIEVVSASETIA
NIQLTNSNVAATAAFNKDALLNWLKEKNTGDALDRAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMVRETGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKPGNAEKFGR
FRQCCEEAYLILRKNGNLFITLFALMLTAGLPELSSVKDIQYLKDSLALGKSDDEALKQF
RQKFDEALRESWTTKVNWMAHIVAKDNRS
>V9KCF9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCCLPNGIMVTLECLREATLVSIKHELFRESRKYPLFH
LLQEETSYIFVGVTQEAEREEFYDETRRLCDLRLFQPLLKVIEPVGNREEKILNREIGFA
IGMPICEFEQVKDSEVQDFRRSILTVCKEAVELRAASGPQSQSLYVYPPNVESTPDLPKH
IYNKLDKGRIIVTIWVIVSPTNDKQKYTLKIPHDYMPEQVIAEAIRKKTRSMHLSSEQLK
LCVLEYQGKYLLKVCGCDEYLLEKFPLSQYKYIRSCIMLGRLPHLMLMSKESLYTQLPVN
TFVMPSYARRISTATSYMNGEVPAKSLWSFNNLLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYMDNLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFNWF
SNSVKFPDAAEIEEHANWSMSRELGFNYCLVGLSNRLARDSSLTDSDIEQLRNIYNRDPL
SEITEQEKDFLWRHRHYCINIPETLPKLLLSVKWNSRDEVAQMYCLLKDWPLIKPEQALE
LLDCNFPDPMVREFAVKCLVKGLTDDRLSQYLIQLVQVLKYEQYLDNPLGRFLLKKALSN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESFCRACGMYLKHLIRQVEAMEKLINLTDILK
QEKKDETQKMQMKFLVEQMSRPDYLEALQGFICPLNPVHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFSNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEAVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEAYDEAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGVQECSKTKEFELFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMP
>A0A4W3GJ76|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MQPYGLELLLEENKRRRRNMRANTTRGMQYYSLEQLSIEIILPTRNKRTAMHEKISLDIA
GNYTVEQLKTKIWVKANGTSGSPEYYQKFSPDQFILLYQKKGQWYEIYDKQQVIQTLDCI
NYWKVLQKSVGKIHVVQKARSSDQSLQLQWDLNNLVGYDVTDVSNVHDDELEFTRRTLIT
PRLTEVATRDVRLYSMDPWILSKPLPEYLLNKISGNNIFMIIHRGAVSLTIKVSIDETPE
SILRNFFKKMAKKMSLLDMNESHSEEHFVLRVCGRDEYIVGDNPIKDFFWIRNCLKNGEE
IHLVLDLPPDPVLDEVQKEEWPLVDDCTGVTGSHEQLTLEGKDHEKVFTISLWDCSQTFR
VKIVGIDIPVLPRNTDVTVFVQASILHGQQILAQQRTPAKAFTEEVMWNMWLEFDIKVKD
LPKGARLNLQVYCGKAQALGSKALEDLWDSRSKNNMLYYVNLLVIDHRSLLRQGEYLLHM
WKIPNKGEEQGTIEADKLTSATNPDKQTSMAICILLDRYNYPIALPRSRQTDPEAERSGP
EMHSQLRKQFEEIVSTDPLNPLSAEDKELLWHFRHECVKQPKAYPKFLSSVKWGQQDVVL
KTHQLLQKQTAWASSPLDVGLALQLLDCRFSDEQVRTMAVQKLETFGNDDVLRFLLQLVQ
AVKFEPYHDSALARFLLKRALGSKRIGHFLFWFLRSEVSESMHYRQRYAVMLECYLRGCG
QAMLMDFMKQVKVIKELQKLTKEIKNVTADKYDISSQAISQLRHRLEKLQSSGFPECFRV
PYDPGLRAGALVVDKCKVMASKKKPLWLEFKCADPTSVSKDTIGIIFKQGDDLRQDMLII
QILLIMDSIWEMESLDLCLLPYGCIATGNKIGIIQIVKDATTIAKIQQSTVGNTGAFKDE
VLNHWLKEKCVIEEKFQSAVEKFVFSCAGYCVATYVLGIGDRHNDNIMITESGNLFHIDF
GHILGNYKSFLGISKERVPFVLTPDFLFVMGTYGKKTSPHFQKFQEICLKAYRTLRHHAN
LLIILFSMMLMTGMPQLTSKEDIEYIRETLTVGKNEEEARTHFLEQIEICRDKGWTVQFN
WFLHLVLGIKQGVEKHSA
>B0EAY0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Entamoeba dispar (strain ATCC PRA-260 / SAW760)|TrEMBL
MIELKRSQYVIPSPYRRTTWQGLPLAQLPKRIETKPLSSGITPSPLSLLKKEDVDEVNEK
KEPRPSNVNVTITQETVFVAVKDRTGKYYGYAMNVNDIGTSIIETCKSNVYIKGDYALVL
PNLSYRVFDEDSRKPLKDLKFVQGCQYHGIVPYFFLVERKAVIQYASVESVGEYLLQSTL
KYEIIGNNFVGLCRNIGDEFYKFRRALATVCGKEEENKKDLDIYLSEENEYVYCGNEPPI
QDLTKKLIMKGYLFEQKMDKTISHLPTDTVENVISALFTKFTTTNQAAFAATEKAEDFVL
KVRGLHEFLIPKKKDGSLYQLCEFDYIRRCVMKHEKIDLYLAPRKMLHQFIGPLNPIDVN
FTGVYNSLLSHDLWEKVETEKAGQSQKSIERNYFITLKKLSNCVYYKPLPQKKNKENKDD
IPVQEYQNIVSFRAYVTAALFLGPRQLGKMVVTPVFQVNNSMATLDNVMEFDLPIKILPK
ETKLVIGVFQTEEQIGVNIEHLEKKEKNKENPIGTINCKVVDHNGMLLMGNVQCGLWELS
APNFISMCSENIGERAIYLTFTYPTYDVPVLMDAFNDDNIKSDNQEKEKLTAEETKKFKV
ALESNPLQKLTEDEMKLIWKLRYTVKKTKPKNLSRVVAAVDLTDVHAVAELHRLISDWPL
LEPQTAIEMLDFKFPDQRVRDFALKCLDAMDDAELIMFLPQLIQALKFELHHNSELAMFL
LRRALRNKNRIGHQFFWFLKAELHDNRVTERYGLLLEAFVGACGKYQIELYNEVKFQLDL
IDIANHVKTLATKDEQKQYMFESLAKLKYPDNQALPIDSRMRFTRPVPNSGNVFSSKKKP
LLLILQNYDPAGDDIRVIEKVGDDLRQDILTLQILRIMYTMLKNAELDIRMLPYQCIATG
NETGMLELVKDSETYGKIIADDGRRLAVTKNDVLTLWMQKQCARPESKVTFEQAVENFVH
SCAGYCVATYLLGIGDRHSDNVMVTRSGVFFHIDFGHFLGNFKSKFGVKRERTPFKFTQH
YADLMGYKDGVESKDFKEFKELCSSALLSLRKQGSLFIYLFRLMLATGIPELKNEDDIEY
MKNAFMFDEDDQQVKKNFDNMIYQCLDAWSQTLNDLIHDIVHYK
>A0A6I9HUP6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vicugna pacos|TrEMBL
MPPGVDCPMEFWTKEENQDVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEAAARRQQLSWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LRVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPASQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERRLYMWPSVPDEKGELLNPSGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTPKPQTKELMHVCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYSILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7J6CJP5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Onychostoma macrolepis|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSPELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTETDIEQLRQLSNRDPL
SEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A8C9JLN8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera tigris altaica|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPEMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C6URL8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neogobius melanostomus|TrEMBL
MSPGKYGMQEEWEKEEAWDQGIMMDFLLPTGIFLKFPVSRNDTIKTIKKMVWKNAKSEAL
FSALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQIS
LLIGKGLHEFEAQKNHEVNEFRTKMRAFCEEKALERQLLPWRLWMEYSFPCDLEPCCSPH
EEGNNKKKNTKIFVNIKFEASEESFMLQQDPQDLPMALVKSALKKKATVFRSVRQEPEDY
TLQVNGRWDFIYGDHPLCQFKYMFSCLRNGQAPQLTMVHHSTISKYQEEQGRMSNQLFQS
RSLSRPPPLPLKKQNTSSLWSINEPFYIQLLHGSRVNADEGMKLVVQAGLFHGSELLCKV
VTSSEVTVRSEPLWDQKLEFDISVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKRADCP
IAWVNTMVFDYKDQLKTGEFLLSAWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPN
IRPHPLYYPPLDKKADVEKNGDASAVSKDELLRLKEIMDNKNYTEFFEDEKELLWKLRYE
VRERYPESLSKLLLITKWNKREEVVLMVSLLRNWPDLPAIQALELLDYSFPDPSVRSFTI
RCLKKLSDPELLQCLIQLVQVLKYESYLDCDLTTFLLERALSNQRIGHFLFWHLRSEIHV
SSVGLRFGLILEAYCRGNIHHIKLLTKQNEALTKMKALSDIVKSGSHKMTVDDLKLCIRQ
ESYMEALSDLLSPLNPSIILTQICADKCRFMDSKMKPLWMMYRNPCFQGEMVGIIFKNGD
DLRQDMLTLQMIHLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSS
NSAATAAFNKDALLNWLKSKNPGDRLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIR
ETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEW
AYKILCHNGILFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEEEALKNFKVKFNEA
LRESWKTKVNWMMHSLAKDNRP
>A0A8C6UM34|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neogobius melanostomus|TrEMBL
MKKLFYKLKPGRKMVWKNAKSEALFSALGDPDAYVFTCINQTAEREELEEESRRISDVRP
FMCVLRLVAREGDRVEKLTNAQISLLIGKGLHEFEAQKNHEVNEFRTKMRAFCEEKALER
QLLPWRLWMEYSFPCDLEPCCSPHEEGNNKKKNTKIFVNIKFEASEVSGFSLGCYSGILS
HEPQASSLTFQHYLFDKEQLCFPEDYTLQVNGRWDFIYGDHPLCQFKYMFSCLRNGQAPQ
LTMVHHSTISKYQEEQGRMSNQLFQSRSLSRPPPLPLKKVRQQVVSGNTKMSIHIVVTEL
VVQAGLFHGSELLCKVVTSSEVTVRSEPLWDQKLEFDISVSDLPRMSRLCFALYAVIEKT
KKPRGTKKKNKRADCPIAWVNTMVFDYKDQLKTGEFLLSAWPSVPDDKSDLLNPMGTVEK
NPNVDSAAGLLIRFPNIRPHPLYYPPLDKKNGDASAVSKDEVNVSSNCLLRLKEIMDNKN
YTEFFEDEKELLWKLRYEVRERYPESLSKLLLITKWNKREEVVLVLLRNWPDLPAIQALE
LLDYSFPDPSVRSFTIRCLKKLSDPELLQCLIQLVQVLKYESYLDCDLTTFLLERALSNQ
RIGHFLFWHLRSEIHVSSVGLRFGLILEAYCRGNIHHIKLLTKQNEALTKMKALSDIVKS
GSHKMTVDDLKLCIRQESYMEALSDLLSPLNPSIILTQICADKCRFMDSKMKPLWMMYRN
PCFQGEMVGIIFKNGDDLRQDMLTLQMIHLMENLWKKEGLDLRMIPYGCLSTGNKMGLIE
VVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPGDRLEQAIEEFTLSCAGYCVAT
YVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGR
TNNSEKFERFREYCEWAYKILCHNGILFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGK
SEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A8C6UPS6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neogobius melanostomus|TrEMBL
MSPGKYGMQEEWEKEEAWDQGIMMDFLLPTGIFLKFPVSRNDTIKTIKKMVWKNAKSEAL
FSALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQIS
LLIGKGLHEFEAQKNHEVNEFRTKMRAFCEEKALERQLLPWRLWMEYSFPCDLEPCCSPH
EEGNNKKKNTKIFVNIKFEASEESFMLQQDPQDLPMALVKSALKKKATVFRSVRQEPEDY
TLQVNGRWDFIYGDHPLCQFKYMFSCLRNGQAPQLTMVHHSTISKYQEEQGRMSNQLFQS
RSLSRPPPLPLKKQNTSSLWSINEPFYIQLLHGSRVNADEGMKLVVQAGLFHGSELLCKV
VTSSEVTVRSEPLWDQKLEFDISVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKRADCP
IAWVNTMVFDYKDQLKTGEFLLSAWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPN
IRPHPLYYPPLDKSNGDFALLVFRLQLLRLKEIMDNKNYTEFFEDEKELLWKLRYEVRER
YPESLSKLLLITKWNKREEVVLMVSLLRNWPDLPAIQALELLDYSFPDPSVRSFTIRCLK
KLSDPELLQCLIQLVQVLKYESYLDCDLTTFLLERALSNQRIGHFLFWHLRSEIHVSSVG
LRFGLILEAYCRGNIHHIKLLTKQNEALTKMKALSDIVKSGSHKMTVDDLKLCIRQESYM
EALSDLLSPLNPSIILTQICADKCRFMDSKMKPLWMMYRNPCFQGEMVGIIFKNGDDLRQ
DMLTLQMIHLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAA
TAAFNKDALLNWLKSKNPGDRLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQ
LFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEWAYKI
LCHNGILFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRES
WKTKVNWMMHSLAKDNRP
>A0A2Y9LXX0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Delphinapterus leucas|TrEMBL
MELENHEQHVVLREDNRRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLHALETSVAADFYHRLSPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRLAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDTKLYAMHPWVTSKPLPEYLLKKITNNYIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIRNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKAEDHGSINADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCSFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIDML
QKVTMDIKSLSAEKYDVSSQVISQLKQKLEILQNLNLPQSFRVPYDPGLKAGALVIEKCK
VMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDL
CLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQ
AAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKER
VPFVLTPDFLFVMGTSGKKTSRHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQL
TSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A6P7WR66|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcaecilia unicolor|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCIPNGMIVTLECLREATLLGIKHNLFKEARKYPLFH
LLQDESSYIFVGVTQEAEREEFYDETRRLCDLRLFQPILKVIEPVGNREEKILNREIGLI
IVTIWVIVFPNNDKQKYTLKIPHDCLPEQVIADAIRKKTRSMHLSPEQLKLCVQEYQGKY
ILKVCGCDEYLLEKYPFSQYKYIRNCITIGRLPHLMLMSKESLYSQLPANIFIMPSYARR
SVTSCYMNGDVPTKSLWSINSLLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNV
NTQRVPCSNPRWNEWLSYDMYLTDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFD
YKDTLVAGKMALNLWPVPHGLEDLLNPIGVGGSNPNKETPCLELEFSWYTHAVKFPDTPQ
IEEHANWSMSRELGLNYCLVGLSNRLARDSSLIENEMEQLRNICNRDPLSEITEQEKDFL
WRHRQYCINIPETLPKLLLSVKWNSRDEVTQMYCLLREWPLIKPELSLELLDCNFPDPMV
REFALKCLVKGLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLIKKALTNQRIGHFFFWHL
KSEMHSKTVSQRFGLMLEAFCRGCGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKMQ
MKFLMEQMRRPAYMEALQGFICPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSE
LLFTNNEIIFKNGDDLRQDMLTLQIIRIMENMWQNQGQDLRMLPYGCLSIGDCVGLIEVV
KNSHTIMQIQCKGGLKGALQFNSNTLHHWLKDKNKGEGYDAAIDLFTRSCAGYCVATFIL
GIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQEC
TKTKEFERFQEMCYKAYLVIRQQANLFINLFSMMLGSGMPELQSFDDIAYLRKTLALDKT
EQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPLSEAGHD
>A0A8D2K449|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Theropithecus gelada|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNP
TGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKLLGGTLLASRGWRPELPWICLHARD
SAPSRMMGVATPCLGVLPGLVQALGDAECSCLLQILELGRHSECVHVTEEEQLQLREILE
RRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQDALPAVSWPELPV
LSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDR
ALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSSGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A091LEE4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chlamydotis macqueenii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGSFDDIAYIRKT
LALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A4W4HIH0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MPPGVCYGMQDVWEKGGREQVTLEFLLPTGIYLSFPVARNDTIGTIKKMVWKNARSEPLF
SVLSDPDAYVFTCINLTAEREELEDESRRLCDVRPFMPVLRLVAREGDRVEKLINTQISL
LIGKGLHEFDTQKNHEVNEFRAKMRSFCEENAQDRQRLPWHQWMKCNFPCDLEPFSMVVQ
SGKSCSVKKLLESFMLQLDPQDFPVVLMQNALRKKATVFRPLKQEKPENYTLQVNGRWQF
IYGNSPLCQFKVRGLASCLPRCTLGAFKFCLRFTEVLDGASSVRYAPLFQQQNTSSLWSI
KEPFFIQLVHGTRVNTDEGMKLVVQAGLFHGGELLCKVVTSSEVSVCSDPVWDQKLVFDI
NLCDLPRMSRLCFTLYGVLEKTKKQRSTKKKNKKADCPLAWVNTMVFDYKDQLKTGEFLL
STWPSAPGDLLNPMGTVERNPNIDSTAGLLIRFPSFRPHPLYYPPLEKVYTALTRCDPSR
CCSQHLKLKEIVDNKNHTEFFEHEKELLWKLRLDVRAHYPESLSKLLLITKWNKHEDVAQ
MVCLLRTWRDLPPLHALELLDYTFPDPHVRSFTIRCLKKLGDEELFQYLLQLVQVLKYES
YLDCDLTTFLLERALSNKKIGHFLFWHLRSEMHVASVSLRFGLILEAYCRGSIYHIKSLM
KQIEALNKMKALNDFVKSGSQKSASRLQITEDMKLCIKQDTYMEALSDVISPLSPSIVLS
EICPDRCKFMDSKMKPLWLMYKNKWDHLDTVGIIFKNGDDLRQDMLTLQMIQLMDVLWKT
EGLDLRMVPYGCLSTGNKTGLIEVVKNADTIANIQRNSSNNAATAAFNKDALLNWLKSKN
PEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKAKF
GINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMRA
AGLPELSCSKDIQYLKDSLALGRSEEEALKNFKVKFNEALRESWKTKVNWMMHTVAKDNR
>A0A851WKT3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Corvus moneduloides|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAAEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFSLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P4WH61|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera pardus|TrEMBL
MELDNYEQPVVLREDNRRRRRRMKPRSTTASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVATDFYRRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQIHVVQRHAPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCSKAPVLAGKTSAETPSSESKGKTQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTDQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIENQTRERAAWLKSPLPSCQQRPSH
SSSGSGPKPQCLSAFVHLLIGMIEIVKEATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCP
IEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFL
GINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLM
TGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQ
GEKHSA
>A0A024R720|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A6J2AC14|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acinonyx jubatus|TrEMBL
MELDNYEQPVVLREDNRRRRRRMKPRSTTASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVATDFYRRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCSKAPVLAGKTSAETPSSESKGKTQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTDQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIENQTREIAAWLKSPLPSCQQRPSH
SSSGSGARPQCPSASVHLLIGMIEIVKEATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCP
IEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFL
GINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLM
TGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQ
GEKHSA
>I3L5R8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MCFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDYPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSIGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A2K5NAR6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cercocebus atys|TrEMBL
MELENYEQPVVLREDNCRRRRRMKPRSVAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVASDFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAQVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPAVSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDTCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8D1M1M5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPGVDCPMEFWTKEENQSVDVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKVSQRLALPLPSSPSSPCRRPTREPIGQHSGPGAGPGPLTQAPWLVHVKSR
AFEHLWPTGPVCGGGALRPPLSSQDLLPARLAEFHSLGSSEVSGPSGTCAAGLPVTAGVV
GSTELYRKPAKPPPTPPAMTTGLVTGASLLRIPLLQWPCFSVHLHTQPSSVSLWSLEQPF
CIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSVCSDPVWKQRLEFDINVCD
LPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWP
SVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAPHPVYYPSLDKILELGRHGEHGRF
TEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNRHEDVAQ
MLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYES
YLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLM
KQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDPSILLAE
VCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQ
EGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKN
PGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKF
GINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYAILRRHGLLFLHLFALMRA
AGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNR
Q
>A0A6P6ES86|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Octodon degus|TrEMBL
MELENSEPAVILREDNLRRRRRMKPRSAAASLSPTELLPIEFVLPTSQRHSKEPETVLLH
VAGHGNVEQMKAQAWLRALETSTASDFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKALHQSPGQIHLVQRHAPSEETLTFQRQLTALMGYDVTDVSNVHDDELEFTRRRL
VTPRLAEVACRDARLYAMHPWVTSKPLPEYLSKKIANNHIFIVLHRSTTSQTIKVSADDT
PATILQSFFTKMAKKKSLMDIPESQGEQDFVLRVCGRDEYLVGDTPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDAVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKVRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCGKTPGLSESRGKAQLLYYVNLLLIDHRFLLRHGEYVLHMWQIPGK
GEDQGSVNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPNQ
LRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGEQETVAKTYQL
LSRREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFE
PYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGAAMLQ
DLAQQVHVIEMLQKVTIDIKSLSAEKYDVSAQVISQLKQKLENLQNSNLPKSFRVPYDPG
LKAGTLVIEKCKVMASKKKPLWLEFKCADLTALSNETIGIIFKHGDDLRQDMLILQILRI
MESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHW
LKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILG
NYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVKAYLALRHHTNLLIIL
FSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHL
VLGIKQGEKHSA
>A0A1A8LNA3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius pienaari|TrEMBL
MPPAMTDLLDIWASHSPLAGHALEKITVDFLLPTGIYIQMDVPRDATIQHIKLLLWKQAQ
NFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRCKMFRITEEKMQQAQVMTCAEWLQACCSPQLEPT
AATLITDGVNDRPADLKVFIHFDQSQDSTSLKVPMSCTPSELMEIAVKKWLTTHAPEDEA
YSRQYVLRVSQCLEFLCGDHPLIQYKYIRNCLQAKESPHLTLVHTSTVKIMFDKEMSAIG
AVVSRKSSNPPLPLPPKRRTPTQVQTSVWNVSKPFRIDLLKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSDSSGRSEHIWKNNTLKFELSVSDLPRMTRLCFAIYAVTDKVKKQKST
KNAHSSKYQTIRKAGKVLYPIAWVNTMVFDYRGQLKTGDVILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHPVIFPPFDKILEKAAQLVGVIEQPIGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVSCLHDMSDEELLQYLLQLVQVLRYEPYYDCPLTH
FLLERAQRNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSEALSDLTSPLNPSVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLMSGDALGIIFKNGDDLRQDMLTLQILRLMDLLWKESNL
DLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQEGKTGNTEKFGSFRKYCEEAYLILRRNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKNDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A6J2BJI7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zalophus californianus|TrEMBL
MSGMELKHHEQPVVLREDNGRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRNSKTPETA
LLHVAGHGNVEQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQ
TLDCLRYWQVLHRSPGQIHVVQRRAPSEETLAFQRQLTALIGYDVTDVSNVHDNELEFTR
RRLVTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSA
DDTPGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCL
KNGEEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDC
DRKFRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFS
IKIKDLPRGALLNLQIYCSKAPALSGKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRH
GEYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPD
PEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVK
WGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVIL
EAYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNS
SLPESFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLYFQKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGEKHSA
>A6QPT0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos taurus|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASMSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGNHQHEPGK
>B0BLW6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus tropicalis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMVVVLECLREATLVNIKHELFKEARKYPLYH
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVVEPVGNREEKILNREIGFA
IGMPVCEFDMVKDSEVQDFRKNILNVCKDSVELRDANGPISRALYVYPPNVESSSELPKH
IESKLDKGQIIVVIWVIVSPNNEKQKYSLKINHDCVPEHVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKDSLYSQIPVD
VFTMPSYSRRISTAAPYMNGEASAKSLWAINSTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGVEPLCDNVNTQRVPCSNPRWNEWLLYDMFIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVSGSNPNKETPCLELEFDCF
SSPVKFPDMTAIEDHANKVLEREMGYNYSHSGLSNRIVRENEVRESDKEQLKAISNRDPL
SEITEQEKEFLWSHRLYCRNIPEILPKLLLSVKWNCRDDVSQMYCLLKEWPAIRPEQAME
LLDFNYPDRIVRSFAVSCLEKYLTDDKLSQYLIQLVQVMKYEQYLDNHLVRFLLKKALVN
QRIGHFFFWLLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSKQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMKRPDFMDALQGFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSEMLFLNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRCSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGETYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDNGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGIQECTKTRDFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKHL
>A0A3B3DEM6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias melastigma|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDFEVQDFRRNILNVCKDAVELRDANGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRLPNLMLMAKDSLYSQLPTD
SFVMPSYCRRISTATSYMNGEAAPKSLWTISGGLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLNYDMYILDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEHF
SSPVKYPDMNAVEEHANWTISRELGFNYNISGQSNRVARDHALTDSDSEQLKQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKFLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNRGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKGEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A384D4P5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus maritimus|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRHSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLLDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIQI
KDLPRGALLNLQIYCSKAPAPTGKGSADTPGSEGKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLEAY
LRGCGTAMLHDFSQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>W5L1G2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MPPGVCYGMQDVWEKEGREQVTMEFLLPTGIYLSFPVARSDTIGMVWKNARSEPLYSVLS
DPDAYVFTCINRTAEREDLEDEQRRLCDVRPFMPVLRLVAREGDRVEKLINTQISLLIGK
GLHEFDSQKNHEVNEFRTKMRSFCEEKAQERQRLPWHQWMEYNFPCDLEPFSIVAQSGKS
RSVKKIIVNVKFEASEESFMLQVDPQDQPVVLMRSALRKKATVFRQSKQEKPEDYTLQVN
GRMEFIYGKYPVCQFKYIFSCLCGGQTPHLTMVHHSAILKYQEEQGSLSNQVSKSRSLSK
PPPLPLKKLVVQAGLFHGSELLCKVVTSSEVSVCSDPRWDQKLVFDISLCDLPRMSRLCF
ALYGVLEKSKKQRSTKKKNKKADCPLVWVNTMVFDYKDQLKTGEVVLSTWPSAPDDKGDL
LNPMGTVERNPNIDSTAGLIIHFPNFRPHPLYYPPLDKIDVRQCCHLKLKEIVDNKNHTE
FFEDEKELLWKLRGEVRAHYPESLSKLLLITKWNKHEDVAQMVCLLRKWRDLPALHALEL
LDYSFPDPHVRSFTIRCLRKLRDDELFQYLLQLVQVLKYESYLDCDLSTFLLERALSNKR
IGHFLYWHLRSEMHISSVSLRFGLILEAYCRGSIYHMKNLMKQNEALNKMKALNDFVKSG
CQKSTSKSQITEDMKLCIKQDTYLEALSEIVSPLNPNILLCEICTDKCKFMDSKMKPLWL
MYRNKWLQSDSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRDKLDQAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKAKFGINRERVPFILTYDF
VHVIQQGRTNNSEKFERFREYCELAYKILCRNGTLFVNLFALMRAAGLPELSSSKDIQYL
KDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMVHTVAKDNR
>A0A7K5YCS4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pterocles burchelli|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKYEYLYGNYPLFQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
VKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAAEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRHS
IRDQFPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>Q4STD4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tetraodon nigroviridis|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKHPISQYKYIRSCIMLGRMPNLMLMAKDSLYSQLPTD
NFVMPSYSRRISTATSYMNGEVAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDTVNTQRVPCSNPRWNEWLTYDMYISDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLEMEFDHF
SSSVKYPDMNAVEDHANWTISREMGLNYTLSGQSNRAARDHILTESDSEQLRQLGNRDPL
SEITEQEKDFLWRHRYYCMKIPEILPKILLAVKWNSRDEVAKMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVKTAACVNPRLLLAQFVLEEEDRMHVCKTVCVCLVKVQMRFLVDQMKRPDY
MDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNG
DDLRQDMLTLQIIKIMENIWQSQGLDLRYYFLLGSVLICSCRSCIQNAVLLLCVSRMLPY
GCLSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDMAVDL
FTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVL
TQDFLIVISKGSQECVKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSF
DDIAYIRKTLALEKSEQAMGLFSFLISSSVLKGVFQITNLPDLHISFGFFPQEALDYFMK
QMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A6J1ZI09|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acinonyx jubatus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLLERPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPLWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSAPDEKGELLNPAGTVRSNPNTESAAALVICLPEVSP
YPVYYPALDKILELGRHGEHGRFSEEELQLREILERRGSGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPDLPVLSALELLDFSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMRQGEALSKLKALNDFVKVSSQKTTRPQTKELMHLCMRQ
ETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDSSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGPLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A671T5H8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MDFLFLFNFLDRYFSDDEPPVVRREENKRRRRKMKAFPSTSAVSTDHIAVEFVLPTTNKN
SRNPDTLHIDVTGNWTVEQVKVQIWHRVVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIY
DKQQVFQTLDCIRYWKALRKEVGKIHLVVRTQPTEDSLQYQRFLNHLIGYDVTDVSNVHD
DELEFTRRKLLTPRKIELSDRDPKRYSMDPWMTTKPLPEYLLSKISNNHILVVIHKDTTS
QTIKVSIDDTPVQVLQSFFAKITNKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDF
HWIRQCLKNGEEIHLVLERPPDPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVF
TISLWDCNRKFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLW
NTWLEFNIKIKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVDHRSLLR
QGEFILHMWKMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDQYCYPVALPKSKDSP
NSEMEGERGQREMPNHMRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLS
SVKWGKQEAVTITHRLLERSTVWDRSSLDVGLALQLLDCHFSDENVRTMAVRKLETLAGD
DVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYA
VILEAYLRGCGEAVLQDFRKQVEMTEALHKVTREIKQMSAEKYDVSAQVVFQLRQKLEGL
QTSGLPDSFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKD
GDDLRQDMLILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQS
TVGNTGAFKDEILSQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMI
TETGNLFHIDFGHILGNYKSFMGISKERVPFVLTPDFLYVMSTTGKKSSPHFLQFQSVCL
KAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEM
CRDKGWTVQFNWFLHLVLGIKQGVEKRSA
>A0A7J8FB23|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Molossus molossus|TrEMBL
MPPGVDCPMEFWANEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPSRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRKPLVEQPEDYA
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPCSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVCSNPNTESAAALVICLPEVAS
CPVYYPALDKILELGRHGEHGRATEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPQTKELMHLCMR
QETYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A671T6B9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
GILETYHDDEPPVVRREENKRRRRKMKAFPSTSAVSTDHIAVEFVLPTTNKNSRNPDTLH
IDVTGNWTVEQVKVQIWHRVVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQT
LDCIRYWKALRKEVGKIHLVVRTQPTEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRR
KLLTPRKIELSDRDPKRYSMDPWMTTKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSID
DTPVQVLQSFFAKITNKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLK
NGEEIHLVLERPPDPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCN
RKFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNI
KIKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVDHRSLLRQGEFILHM
WKMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDQYCYPVALPKSKDSPNSEMEGER
GQREMPNHMRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQE
AVTITHRLLERSTVWDRSSLDVGLALQLLDCHFSDENVRTMAVRKLETLAGDDVLRYLLQ
LVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLR
GCGEAVLQDFRKQVEMTEALHKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDS
FKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDM
LILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAF
KDEILSQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFH
IDFGHILGNYKSFMGISKERVPFVLTPDFLYVMSTTGKKSSPHFLQFQSVCLKAYLALRH
HTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEMCRDKGWTV
QFNWFLHLVLGIKQGVEKRSA
>A0A8C0B7E3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Buteo japonicus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIEGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLPSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIESLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
RLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C0B8K9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Buteo japonicus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPAKNIFVNVRFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGQTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAL
HPVYYPSFEQVGDVDAFFGRLRHSLQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQ
YPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLK
KLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVA
LRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCMKQ
ETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGD
DLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKS
NMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIR
ETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEK
AYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEA
LRESWKTKVNWLAHNVSKDNRQ
>A0A6J0X790|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Odocoileus virginianus texanus|TrEMBL
MELENHKEPVVLREDTCRRRRRLKPRSTAASLSSMELIPIEFVLPTSRRNTETPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHLVQRHAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPTLYAMHPWVTSKPLPEHLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEEDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPVLSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTMDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIA
KIQQSTVGNTGAFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHN
DNIMISETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKF
QDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFL
DQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A2I4KAQ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tachysurus fulvidraco|TrEMBL
MPPAMTDQLDVWADPVLDGNDQVTVDFLLPTGIYIQMDVPRESTIQQIKQMLWKQAQAYP
LFSLLGEMDGHIFECVNQAAVHEELEDESRRLCDVRPFVPVLRLIIRNCGRAERLLDSKI
GVLIGKGLHELDALLNQEVKDFRSKMQRISEEKMQSVQMMSWAEWLQSFFSPQIEVGPVD
GFYDKNEGWIKITMHYNQSQDTTSLKVPLNCTVPELMNQALKKWLTTHGLGEDEDSVGNY
VLRVSDRLEFLFGEHPLAYYRYIRSCLLSQEIPHLTLVQCDIVKAMYEHEISSIGAVFSR
KSSNPPLPLPPKRRGPSQLQTCIWEVQSLFRITLVKGIKVNAEETAKVQVRAGIFHGTEL
LCKPAVSNESSGRSEHTWNRTLEFDISVCDLPRMARLCFAIYAVMDKVKKQKSTKNMQMN
KYQTIRKAGKVHYPIAWVNMMVFDYRGQLKTGDIILHTWSSFPDELEEMLNPIGTIQTNP
YTENATALHIRLPEYSTHPLTFPPFDKILEKAAEIAGSTDSVSMGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKISP
RDALELLDFNYPDQYVREYAVSCLQDMCDEELLQYLLQLVQVLRYEPYYDCALTQFLLQR
AQSNRKIGHFLFWYLRSEIHMPAVCVQFALILEAYCRGSIPHIEVLKKQVEALGKLKAVN
ELIKLGTLKAKNKTKEAQLKEAMMKCLRQTGFIEILSDLHSPLNPQILLADVNVEKCRYM
DSKMKPLWVVYNNKLLVGDTLGIIFKNGDDLRQDMLTLQILRLMDMLWKEEKLDLRIVPY
GCLATGDRTGLIEVVSSADTIANIQKNSSNMAAAAAFNKDALLSWLKDKNPGDALEKAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFI
LTHDFIHVIQQGKTGNTEKFGSFRQYCEDAYLILRKNGNLFITLFALMLTSGLPELTSVK
DIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAHPS
>A0A672U2R3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVHDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMINSIGSVA
SLKFLITLLQVHVRAGLFHGTELLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARL
CFAVYAVMDKMKTKKSTKHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPM
GTVQTNPYTENATALHIRFQEYAKQPINYPPFDKVSCLGISEQQCGKKFYVVLKEIMERD
PLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPRE
ALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERAL
ANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSL
IKLNAMKQSKAKGKDAMQTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKP
LWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A672UWC9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
SGLFHPAVALAQVVWKHAQYEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPF
LPVLRLVAREGDRVKKVINSQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQ
HDSGVIFNDWQPHELVILLELDLKFLISSLMVALLKDSFTFQISPNEFPITLMSYAIKKQ
ATVFRHETLEKPEDYTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIA
MRDEQTNCITSPPKTATKPPPLPKKKVKGGSDPAGSTSNHPLMEMLSLCGNNSWFSLPSS
GQLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVI
EKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGT
VQCNPNTESAAALVICFPSVASHPVYYPSFEQVGTFPTLSYDSHEQKLQLKEILERRSHT
ELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALE
LLDFSFPDRYVGSFAVNSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNR
KIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKA
SSLKATKPQTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWI
VFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKT
GLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGY
CVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVI
QQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSL
ALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKNNRQ
>A0A672UTP9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GPLHIPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAIKKQATVFRHETLEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKTA
TKPPPLPKKKPNYGSLWSLEQSFYIQLVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQ
ALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAVNSLKKLT
DHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRF
GLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMMHVCMKQETY
LEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLR
QDMLTLQMIQLMDILWKQEGLDLSDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCE
KAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNE
ALRESWKTKVNWLAHNVSKNNRQ
>A0A3P8WPJ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cynoglossus semilaevis|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLHN
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDVVKDSEVQDFRRNILNVCKEAVDLRDSNGSHSRALYVYPPNVESSVELPKH
IYNKLDKGQIIVVIWVIISPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKESLYSQLPMD
NFTMPSYARRISTATPYMNGETATKPLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEGHANWNISRELGFNYCHTGLSNRLARDNPLTDGDNDQLRQVCNRDPL
SEITEQEKDFLWRHCLNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIRPEQAMELLD
CNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRI
GHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTELLKQEK
KDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRYPRGMALKYFLELWLNWE
NPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDC
VGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRSCAGY
CVATFILGIGDRHNSNIMVKDDGQVRITFDILLWSFSRPQKEEVWLQEXXXXXXXXXXXV
ISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIR
KTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A3P8VZY2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cynoglossus semilaevis|TrEMBL
MPPAMTDLLDIWVAHSPMLGHTPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TLPLFTALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERLLD
SKIGVLIGKGLHELDAINDQELDPGSTTAVTDEVSEQSDLKVIIHFEQSQDSTILKVPSS
CTTTELMDLAIKKWLTTHSPEEEASRSEYVLRLSQCLEFLCGNHPLSQYKYIRTCMQAKE
SPSLTMVHMSTIKAMFDKEIKTIGAVVNHKSLNPLPLPLPPKRRAPTQVQMCVWDLTSTF
RIVLVSANKVNADETAKVQVRAGLFHGTELLCKPVVSSESSQRSDHTWRESTLEFEISVC
DLPRMTRLCFAIYAVMDKVKKQKSTKNPHLYKYQTIRKAGKVHFPIAWVNTMVFDYKGHL
KTGDINLHCWSSFPDELEEMLNPIGTVQTNPYTENATALCIHFPEYSSHPVVFPPFDKIL
EKAAEIVGASDCSPMGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRCDCRENFPQS
LPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLHDMSD
DELSQYLLQLVQVLRYEPYYDCALTHFLLRRAHGNRKIGHFLFWHLRSEIHMPAVSVQFA
LILEAYCRGSVPHIEVLKKQVDALSKLKSVNELIKHGNTKNARSKTKEAMLTKEAMMACL
KQSGYSETLSDLCSPLNPSVMLSGINVEKCRYMDSKMKPLWIVYNNKLLMGDTLGIIFKN
GDDLRQDMLTLQILRLMDLLWKESKLDFRIVPYGCLATGDKAGLIEVVSSADTIANIQLT
SSNMAAAAAFNKDALLNWLKERNSGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGCFRRYC
EEAYLILRNHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFD
EALRESWTTKVNWMAHNVAKDNRS
>A0A3P8X0H3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cynoglossus semilaevis|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDACGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYTQLPTD
VFLMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDTVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNFNLSGQSNRVARDHALTEGDTEQLKQLSNRDPL
SEITEQEKDFLWRHRHYCMIIPEILPKILLAVKWNSRDEVAQMYCLLKDWPSIRPEQAME
LLDCNYPDPMVRQFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A803YAK5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Meleagris gallopavo|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQVSLLSLKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNA
DERMKLVVQAGLFHGNEMLCKMVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNP
MGTVQCNPNTESAAALVICFPNVASHPVYYPSFEQVGNMDVFLRAWLPRLSHISILLPTS
IFHYTPVFLHLSGLSKAFGLRLSPLYALCCDSHEQKLQLKEILERRSHTELYEHEKDLVW
KMRYDIRDQYPQALAKLLTITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYV
GSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLR
SEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAK
EMMHVCMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGG
VGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDT
IANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGD
RHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKF
ERFRGYCEKAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALK
HFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C7HTF6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MEQQVSDEEEPQPVVLRAEIRRRRRKMKAFTSTFSVAVDQIAVEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCVRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELSDRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVYTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNAWLEFN
IRIRDLPKGARLSLQVNCQHLCGGGSGSHDGSKTKSRLLYYVNLLLVDHRSLLRQGEFIL
HMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYPVALPKSRDGKAAGGEG
REAEGGKRGQREMPNHLRKQFEVIVETDPLHPLSQEDKELLWHFREECMRHPRAYPKLLG
SVLWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLETLGDD
DVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYA
VLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQVVFQLRQKLENL
QTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTTLSSDTIGVIFKD
GDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQS
VVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLGVGDRHNDNIMI
TESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCV
RAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEEAQRHLLDQIEI
CRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A8C7HTB6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MEQQVSDEEEPQPVVLRAEIRRRRRKMKAFTSTFSVAVDQIAVEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCVRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELSDRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVYTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNAWLEFN
IRIRDLPKGARLSLQVSCGKAQTQISKGTSSYQDNGGSPGGGGSGSHDGSKTKSRLLYYV
NLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYC
YPVALPKSRDGKAAGGEGREAEGGKRGQREMPNHLRKQFEVIVETDPLHPLSQEDKELLW
HFREECMRHPRAYPKLLGSVLWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYS
DAHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLF
WFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEK
YDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFK
RADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKI
GMIEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYC
VATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMG
TSGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALT
VGRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A8C7F0S3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
IELQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPTEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIEGAALWATLCCLPVTNSHILLVIHRNKASQTIKVSIDDTPVQALQTFFTKI
SNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCLKNGEEIHLVLESALN
PGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDCHRKFRVKVLGIDIPA
LPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFNIRIRDLPKGARLSLQ
VSCGKTQISKGTSSYQDNGGSPTKSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPEKTED
NSSVNADKLTSATNPDKASSMAVAILLDKYCYPVALPKSREGERGQREMPNHLRKQFEAI
VETDPLHPLSQEDKELLWHFREECMRHPRAYPKLLGSVRWGRQEAVLATHRLLERSSVWD
RSVLDVGLAMQLLDCHYSDAHVRSMAVRKLETLGNDDVLRYLLQLVQAVKFEPYHDSALA
RFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEM
TEALQKVTREIKAMSAEKYDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVI
EQCKVMASKKRPLWLQFKRADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEE
SLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSE
EKFQQAVERFVFSCGGYCVATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGI
SKERVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTG
MPQLTSKEDIEYIREALTVGRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGV
DKRSA
>A0A8C7GUG8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPAMTNLMDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQACFSPQLEPGGG
ATPVTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTIPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISA
IGAVVNRKSSNPPLPLPPKRRGPSQVNTCVWEVSTHFKIVLIKGSKVNAEETAKIQVRAG
LFHGTELLCKPAVSSESSGRSEHVWNRTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKS
TKNAHINKYQTIRKSGKVHYPVAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPI
GTIQTNPYTENTTALHIHLPDYNPHTILFPPFDKILEKAAEIAGSSDCLPMGRGGKKFHI
ELKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQ
IWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCAL
TRFLLNRAQCNRNIGHFLFWHLRSEMHMPAVAVQFSLILEAYCRGSIPHIEVLKKQVEAL
SKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSG
INVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEA
NLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNS
GDALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFG
IKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTA
GLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A8C4AWI3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPTMMDVLDLWAELGEVEHVSVDFLLPTGLYIQMEVPREATIQHIKQLLWKEAAGYPLF
TLLGAMEGHMFECVNQTAVHEELEDETRRLCDVRPFLPVLRVVTRSGGHNERLLDSKIGV
LIGKGLHELDSLQDQEIKDFRTKMQQISKEKIQRIQVMSWEEWLRTHFSPQLEVGQLLIY
DTLCTVRTLLELALRKWANTHGHNNSSCLSDYILRISSKLEILYYVLGICLIFVCVQYIR
ECLLAQESPHLTVMHSSVLRGMFERELGCIASVCGHKQSNAPLPLPPKKRPPSVSTCSQF
KITLVRGIKVNTEESAKVYVRAGLFHGAELLGKPAVSSDSSGRLEHLWNTTLEFDVAVSD
LPRMSRLCFAIYAVMDKVKKQPKSIKTPHSKYQTIRKAGKVHYPIAWVNTMVFDYKGLLK
TGDVVLYCWSSFPDELEEMLNPIGTVQTNPYTENATAIHITFPEYSQISVIFPPFDKILE
KAAEMARGSDCPPMVFHIELKEIMDREPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLL
SVKWNKHEDMAQLQALLQIWPTLSHRDALELLDFNYPDQYVREYAVNCLRDMSDEELSQY
LLQLVQVLRYEPYYDCALSRFLLERSQLNRNIGHFLFWHLRSEMHMPAVSVQFALILEAY
CRSSIPHIEVLKKQVEALNKLKAVNALVKTGAVKSKARTKDSHLKEAMLTCLRQSGFTET
LSDIHSPLNPSVLLAEVNVDRCKYMDSKMKPLWIVYNNKLLGGETLGIIFKNGDDLRQDM
LTLQILKLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADTIANILKTSSNMAATA
AFNKDALLNWLKEKNSGDTLERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLF
HIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTANTEKFGSFRQYCEEAYLVLR
RNGNLIITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFRQKFDEALRESWT
TKVNWMAHHIAHAS
>A0A8C0FRZ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVNFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYTLQVNGKC
EYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMAAKPPPLP
KKKVKETNRSSPCGFMVFPYFSFPQLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRL
DFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTG
ECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVASHPVYYPSFEQVGDVD
FFWGARSAWQAHAGSKDLEWLLLLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALA
KLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDQYVGSFAINSLKKLTDHE
LFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLI
LEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHVCMKQETYLEA
LSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDM
LTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATA
AFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLF
HIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILR
RHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWK
TKVNWLAHNVSKDNRQ
>W5QHQ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ovis aries|TrEMBL
TMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLH
QLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGF
AIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPK
HIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQL
KLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPM
DCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTG
IYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEH
CPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDW
FSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDP
LSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAM
ELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDIL
KQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A6G1PK46|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Channa argus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKHPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCMMLGRLPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAASKSLWTINGTLRIRILCATYVNVNIRDIDKVGMPSEY
RVYTRASIYVRTGIYHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSI
CSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNP
NKETPCLELEFDHFSSPVKYPDMNAVEDHSNWTISRELGFNYNLSGQSNRVARDHALTES
DTEQLRQLSNRDPLSEITEQEKDFLWRYRHYCMNIPEILPKILLAVKWNSRDEVAQMYCL
LKEWPSIRPEQAMELLDCNYPDPMVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLD
NPLARFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQV
EAMEKLINLTDILKQEKKDETQKMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDE
CRIMSSAKRPLWLNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQG
LDLRMLPYGCLSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGE
MYDLAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYK
RERVPFVLTQDFLIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGS
GMPELQSFDDIAYIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A6J0TMS1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pogona vitticeps|TrEMBL
MMPPAMADTLDIWAVDSQIAADGSISVDCLLPTGIYISLDVPRDATICHIKQLLWKQAHS
YPLFHLLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLQLITRSCDPGEKLDSK
IGVLIGKGLHEFDALQDPEVKEFRIKMRRISEEKMHSVVRLSWMDWLKHTYPPELEPTIQ
ENLQDKLYSGNLVVAVHFDNCQDVFSFQASPDMKPIKLNEMAIRKRLTIHGDEDREVDPA
DYVLQVSGRLEYVFGDHPLIQFQYIHHCVMCRTLPQLTLVECSTIKKMCQQEMIAIEAAI
NRKSHNIPLPLPPKKSRVIKSVWDISHPFKVILVNGSKFNTEETAKVHVRAGLFHGTELL
CKPIVSSEISGRNDHVWNESLEFDINVCDLPRMARLCFVVYAVMDKMKNKKSAKTLNTAK
YQTIRKAGKVHYPVAWVNTMVFDFKGQFKTGDFILHGWSSFPDELEEMLNPMGTVQTNPY
TENATSLQIKFQEYSKFPVYYPPFDKILEKAAEIARNSDSSGMAGRGGKKFHIELKEIME
RDPLCQLCENEMDLIWTLRYDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPP
REALELLDFNYPDQYVREYAVSCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLEK
AMANRRIGQMLFWHLRSEVHIPAISVQFGVILEAYCRGSIAHMKVLYKQVEALNKMKTLN
NLIKLNAMKQNRAKGKEAMHACLKQRAYKEALSDLQSPLNPSVLLSELYVEKCKYMDSKM
KPLWIVYNNKVFAGELVGIIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRILPYGCLA
TGDLSGLIEVVSKSETIADIQLNSSNVAAAAAFNKDALLNWLKENNSGDDLDRAIEAFTL
SCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYD
FIHVIQQGKTGNTEKFGRFRQCCEEAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKSDEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C8X4K4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera leo|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GPLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLLERPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSAILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSAPDEKGELLNPAGTVRSNPNTESAAALVICLPEVSP
YPVYYPALDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPDLPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMRQGEALSKLKALNDFVKVSSQKTTRPQTKELMHLCMR
QETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDSSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGPLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C5ERR0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRKNILNVCKEAVDLRDSNGPHSRSLYVYPPNVESAPELPRH
IYNRLDKGQIIVVIWVIVSPTNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMTKDSLYSELPTN
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLQYDMYIPEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPEMTIVEEHANFNISRELGCNFSHSGLSNRLARDNPLTDSDNDQLRQICNKDPL
SEITEQEKDFLWRHRHDCTNVPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAIE
LLDCNFPDPMIREFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLGRQVEAMDKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFVSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8C5I269|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
MPPGKYGMQEEWEKEGDQEILMDFLLPNGIFLNFLVSPNDTIKTIKKMVWKNARNEALFN
GLGDPEGYVFTCINQTAVREELEEESRRIRDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRSKMRSFCEEKAQKRQGLPWQQWMEYSFPCDLEPCSAKSKN
KKKIFINVKFEASDESFMLQQEPQDLPLALMRSALKKKATVFRSLRQEPEDYTLQVNGRW
EFIFGKHPLCQFKYIFSCLRNDENPQLTMVHHSTISKYQEEQGRMCNHIYRSCAMSRPPP
LPQKKLVVQAGLYHGSELLCKVVTSSEVTVCSEPLWDQKLDFDINVADLPRMSRLCFALY
AIIEKAKKPRGTKKKNKKADCPIAWVNTMVFDHKDQLKTGEFLLSTWPSVPDDKSELLNP
MGTVEKNPNVDSAAGLLIRFPNILPHPLYYPPLDKVLICVTEENGETEIMDNKNHTEFFE
DEKELLWKLRTDIRDCYPESLSKLLLITKWNKREDVVQMVSLLESWPELPAIHALELLDY
SFPDPAIRSFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCVLTTFLLERALANRRIGH
FLFWYLRSEIHVASVSLRFGLILEAYCRGNIHHMKVLTKQNQALVKMKALNDFVKSGSQK
MTVEDLRLCVKQESYMEALSDLLSPLNPSVILAEICADKCRFMDSKMKPLWLMYRNPWPH
ADMLGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKN
SDTIANIQLNSSTSAATAAFNKDALLNWLKSKNPEDKLEQAIEEFTLSCAGYCVATYVLG
IGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGKTNNS
EKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEDE
ALKNFKVKFTEALRESWKTKVNWMMHSLAKDNRP
>A0A7L2U1E0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balaeniceps rex|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKIPEMMLLE
IAGNCTVEQMKAQIWMRAIEISQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGIRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEK
>A0A7K5DUI1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Polioptila caerulea|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNADLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNVWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8D3DUP7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPGKYGMQEEWEKEGVQEIMMDFLLPTGILLKFPVSRNDTIKSIKKMVWKNARSEALFC
GLGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRAEKLINTQISLL
IGKGLHEFEAQKNHEVNEFRTKMCIFCEEKAQERQMLPWQQWMEYNFPCDLEPFGKPKTN
AQHFMLQQDPQDHPVALMRSALKKKANVFRSVRQEPEDYTLQVNGRWEYIYGKHPMCQFK
YIFSCLRNGQNPHLTMVHHSTISKFQEEQGQMCSQEYKSRSLSRPPPLPLKKVRGQRTAG
LVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEK
TKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVE
KNPNVDSAAGLLIRFANIRPHPLYYPPLDKVLVPKRLCWVHTEILISHILQLSHCERKKK
HTELLWHLRTEVRDRYPENLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYS
FPDPAIRSFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHF
LFWHLRSEIHVASVTLRFGLILEAYCRGNIHHIKLLTKQNEALSKMKTLSDFVKSGSQKL
TAEDLKLCIRQESYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNNWAPE
DMVGIIFKKGDDLRQDMLTLQMIQLMETLWKREGLDLRMIPYGCLSTGNKMGLIEVVENS
DTIANIQRNNSNRASLTQRLDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYK
ILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDNRP
>A0A6A5FBB5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Perca fluviatilis|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSSVKYPDMNAIEEHANWTISRELGFNYNLSGQSNRSARDHALTENDTEQMRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPSTRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8C3UM36|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Catharus ustulatus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYSMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSEVDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHEPSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GDYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQEAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A2U9B5Q6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQIPVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TLPFFAALGDMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVMKLVMRNCGRAERLLD
SKIGVLIGKGLHELDAMNDQEVKDFRSKTFRISEERMQGVQMMTCTEWLQSCFSPQLEPD
VADGAADWSADLKVIIHFDQSQDSASLKVPSSCTTTELMELAVRKWLTTHGPEEEAWRSQ
YVLRLSQCLEFLCGNHPLIQYKYIRTCVQAKESPHLTLVHNSTVKALFDKELSTIGAVVS
RKSSNPPLPLPPKRRVPTQVQTCVWDMSSPFKIVLVNASKVNAEETAKVQVRAGLFHGTE
VLCKTAVSSESSGRSDHTWKESTLEFDIPVSDLPRMTRLCFAIYAIMDKVKKQKSTKNTH
INKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDINLHCWSSFPDELEEMLNPIGTIQT
NPYTENATALYIHFPEYSSHPVIFPPFDKILEKAAEIAGASDCFPAGRGGKKFHIELKEI
MERDPLSQLCENEKDLIWTLRWDCLVNFPQSLPKLLLSVKWSKHEDMAQLQALLQMWPKL
SPRDALELLDFNYPDQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLL
ERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKS
VNELIKLGPTKNARSKTKDAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSGINVER
CRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLR
IVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNTGDALE
RAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRER
VPFILTHDFIHVIQQGKTGYTEKFGRSVPQRIPPSGRFRCSVC
>A0A1A8IMT1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius kuhntae|TrEMBL
MPPGKYGMQEEWEKEGDQNILMDFLLPTGIFLKFPVPRNDTIKNIKKMVWRNAKSEALYC
GLGDPEGYVFTCINDTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNSHISSL
IGKGLHEFEAQKNHEVDEFRSKMRTFCEEKALERHNLPWQQWMEYSFPCDLEPCCSPPVH
GGTKSKHTKKLFINVKFEACDESFMLQQDPLDIPVALMKSALKKRATVFRSVRQEPEDYT
LQVSGRWEFIYGNHPLGQFKYIFSCLRNGQNPQLIMVHHSTISKYQEEQGQLCSQAVGKI
RSQSRPPPLPMKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKV
VTSSEVTVCSEPLWDQKLDFDINVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKRADCP
IAWVNTMVFDYKDQLKTGEFILSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPN
IRPHPLYYPPLDKMIVMERNGDAVFATKVERMRLKEIMDNKNSTEFFEDEKELLWKLRTE
VRDCYPESLSKLLLITKWSKREDVVQMVSLLRNWPDLPAIQALELLDYSFPDPAVRSFTI
RCLRKLSDNELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHV
ASVSLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDIVKSGCQKMTVEDLKLCIRQ
ESYMEALSNLMSPLNPSIILVELCADKCRFMDSKMKPLWMMYKNPSEHADMVGIIFKNGD
DLRQDMLTLQMIHLMEDLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKHSDTIANIQRNNS
NSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIR
ETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEW
AYKILCKNGTLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEDEALKNFKVKFNEA
LRESWKTKVNWMMHSLAKDNRP
>A0A4W2I4P5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos indicus x Bos taurus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPFLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLSSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A4W2H2H2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos indicus x Bos taurus|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASMSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQRENNHVKSII
IKHWHQRCC
>A0A7K6P2T2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ifrita kowaldi|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYSFPLQLEPMAKGLGT
GSLQIPNKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8J6H099|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microtus ochrogaster|TrEMBL
MCLSSIMPPAMADILDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISSIKQMLW
KQVHNYPLFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEDKIQSLVGLSWIDWLKHTYPPEH
EPSVLENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNLTPIKINELAIQKRLTIHGKEDE
VSPYDCVLQVSGRVEYVFGEYPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKMHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQ
TNPYAENATALHIKFPDNKKQPYYYPPFDKIIEKAAEIASGDSANMSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALDNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYSSRGFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7L0NBV1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Formicarius rufipectus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVLWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAARRQQLGWAAWLEYSFPLQLEPLAKGLGP
GSLQTPTKNIFVNVRFQSGGESFTFQISPREFPITLMSYAIKKQATVFRHETLQKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKVA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWRQRLDFDILICDLPRMARLCLALYAVIEKAKKARATKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMIFLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEEAGGGGVGMIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A4W6CFM5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MPPGKYGMQEEWETEGVQEIVMDFLLPTGIFLKFPVSRNDTIQNIKRMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEETRRISDVRPFMGVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPQC
GNTKTKNIKKIFINVKFEACDESFMLQQDPQDHPVVLMRSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGKHPLCQFKYIFSCLRNGQNPYLTMVHHSTISKYQEDQGRMCSQVYKSR
SLSRPPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPPLDKISDIERNGDASISTKEEYMKLKEIMDNKNYTEFFEDEKELLWKLRAEV
RDRYPESLSKLLLITKWNKREDVVQMVSLLRNWPDLPAIHALELLDYSFPDPAVRSFTIR
CLRKLSDGELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWYLRSEIHVA
SVSLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKGSQKMTADDLKLCIRQES
YLEALSDLLSPLNPSIILAEICADKCRFMDSKMKPLWLMYKNHFTQGDMVGIIFKNGDDL
RQDMLTLQMIQLMETLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNS
AATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIADRHNDNIMIRET
GQLFHIDFGHILGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAY
KILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEDEALKNFKVKFNEALR
ESWKTKVNWMMHSLAKDNRP
>A0A7L0R9Z3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Glaucidium brasilianum|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHGELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDSPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRITSD
TQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIESLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
NLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGSSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A093CRL1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pterocles gutturalis|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEVMLLE
IAGNCTVEQMKAQIWMRAIEMSQTVDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHGELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIVGIDIPILPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHECPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVSKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A803WFA6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ficedula albicollis|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQDPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAIYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLRSGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLREDLDRAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3P9NIH1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia reticulata|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDNNGCHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMSKESLYSQLPME
NFTMPSYARRISTATPYMNGETATKCLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYVTEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMSMIEDHANWNISRELGFNYSHPGLSNRLARDKPLTESDNEQLRQVCNRDPL
SEITEQEKDFLWSHRHYCINIPDILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHALHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A2K5MG99|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cercocebus atys|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHLWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A671VX98|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MPPAMTDLLDIWAAHSPLAGHALDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRMSEERMQRVQMMTYTEWLQACFSPQLEPT
AGTAITDGLNDRPADLKVIIHFDQSQDSASVKVQSSCTPMELMELAVRKWLTTHGPEEET
WRGQYVLRVSHCLEFLCGDNPLIQYKYIRTCMQAKEPPHLTLVHTSNVKAMFDKDITAIG
AVVTHKSSNPPLPLPPKRRVPTQVQTCVWDVSIPFKIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESSGRSDHTWKDSTLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKST
KNAHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGELILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSPHSIIFPPFDKILEKAAEILKANDCVPLTRGGKKFHIE
LKEIMERDALSQLCENEKDLIWTLRHDCIENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLCPRDALELLDFNYPDQYVREYAVRCLRDMSNEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALS
KLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQISYSETLSDLYSPLNPNVLLSGI
NVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDGRWNQRTGERRIVPYGCLATGDR
AGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFTLSCAG
YCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHV
IQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDS
LALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A5J5D6Z3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Etheostoma spectabile|TrEMBL
MEPDLIDADFSLHILQALLDDGDEGSRGHQGSIDVGLADVALYAKERKRKEKVQFTARLT
RLLQPGETEIRSPSLPLCEGVLAASEEMTGREREVAHVRCCCAKRGPNDFVLTAEVLRIK
QMFFVAGAKNTAGAGRGNERRSIYKKFREVDLLDKKKTVTALKPGEDRAIFLGLGMILSS
VMMYFVLGITILRSYADSVWTEEGLCVVLNSTVTADMNCSYNCGSDCWRVSKYPCLQVYV
SVNNTGRVSRLSHNEETQDVSSECFYVPRCQKDSVAMHAMIMKISEHLKVNQKVPCYYDP
SEQQEMVLLTPLHDHSVVFHSLLWPSCMLIGGALIIVMVKLTQYLSRLCEEMGKIKRFVG
TTMPPRPSSGELWGMHLMPPSILVDCLLPNGMLLTLECLREATLITVKHELFKEARKYPL
YNLLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIE
VQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESCAELPRHIYNKLDKGQIIVVIW
VIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLKMCVQEYQGKYILKVC
GCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMDNFTMPSYARRISTAT
PYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQLCDNVNTQR
VERVAELRHEHCPLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNK
ETPCLELEFDHFSCPVKYPDMTIIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDADN
EQLRQVCNRDPLSEITEQEKDFLWRHRQHCVNMPEILPKILLAVKWNSRDEIAQMYCLLK
DWPAIKPEQAMELLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNP
LARFLLKRALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEA
MEKLINLTDLLKQEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEE
CRMMSSAKRPLWLNWENPDMISEAGHANTADH
>F6SW23|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gallus gallus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPIRETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A5F8GF37|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodelphis domestica|TrEMBL
MFFNLKTNTYFRAKLTVYFSNHYLQMLWKQAHSYPMFNLLMEIDSYMFACVNQTAVYEEL
EDETRRLCDVRPFLPVLKVVTRNCDPGEKLDSKIGVLIGKGLHEFDALEDPEVMEFRSKM
RQFSEEKIQSLIGLSWMDWLKHTYPPEQEPSIPENLEDKLYGGNLVVAVHFENCQDVFSF
QVSPNMNPIKLNELAIRKRLTIHGKEDEVDPYDYVLQVSGRLEYVFGDHPLIQFQNVWEN
TQPFQIVLVKGTKLNTEETVKVHVRAGLFHGTELLCKPVVSSEISGRNDHVWSEPLEFDI
NICDLPRMARLCFAVYAVDKVKTKKSTKHYPVAWVNTMVFDFKGQLKSGDIILHSWSSFP
DELEEMLNPMGTVQTNPYTENATALHIKFPENKKQPYYYPPFDKVSELPCKIKILSSFLL
FSHFSCGKKFHVVLKEIMERDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSVKWNK
LEDVAQVSSSSIWPKLPPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQV
LKYEPFLDCALSRFLLDRALANRRIGQFLFWHLRSEVHIPAFSVQFGVILEAYCRGSVGY
MKVLSKQVEALNKLKTLNSLIKLNAMKLNKAKGREAMHTCLKQNAYREALSDLQSPLNPC
VILSELYVEKCKYMDSKMKPLRIVYNNKVFGGDPVGVIFKNGDDLRQDMLTLQMLRLMDL
LWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWL
KEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVRKTGQLFHIDFGHILGNF
KSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFA
LMLTAGLPELTSVKDIQYLKDSLALGKSDEEALKQFKQKFDEALRESWTTKVNWMAHTMR
KDYRS
>A0A6Q2Y7B6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPTD
CFSMPSYARRISTATAYMNGETSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLAYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSAVKFPDMATVEEHANRTISRELGFNYSQSGQSKRVARDHALTDIDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNIRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLLYGCMS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A6Q2YRX7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPVEYGMLGEWEKEGDLEIMMDFLLPTGIFLKFSVSHNDTIGMVWSNASNEPLYGALSD
MDAYVFTCINSTAEREELEDETRRLCDVRPFMPVLRLVAREGDRVEKLTNTQISLLIGKG
RNYYYYSLHKLMKIVNEFRAKMRSFCEERALERQQLPWYQWMEYSFPCELEPCVLLAEPG
GIKTKCKKIFVNVKFEASDESFMLQHEPQDLPVTLMRSALKKKATVFRSVHQEKPEDYTL
QVNGRWEFIYGKYPLCQFKYIFSCMRGGQTPHLTMVHHTTIVKYQEEQGRLASQVSRCRS
LSKPPPLPLKKNTSSLWSIEEPFNIHLIQGNRVNADEGMKLMVQAGLFHGSEMLCKVVTS
GEVNVCSEPLWDQKLVFDINVSDLPRMSRLCFALYAVIEKNKKPRSTKKKNKKADCPLAW
VNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNIDSAPGLLIRFPNIRP
YPLYYPPLEKMSELERKGEKLKATKEEMVDLLHKWPELPALHALELLDYCFPDPRVRSFT
IRCLRKLSDEELLQYLLQLVQVLKYESYLDCDLTTFLLERALANKRIGHFLFWHLRSEMH
VSSVSLRFGLILEAYCRGNICHIKSLWKQNEALNKMKAVNDFVKSGWQKTSRQQMTDDMK
LCIKQEAYIWALSNLLSPLNPSIILSEICADRCKFMDSKMKPLWLMYKNKCVQGEAAGII
FKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSETIANI
QRNNSNSAATAAFNKDALLNWLKSKNPEDKLDNAIEEFTLSCAGYCVATYVLGIGDRHND
NIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFR
AYCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKVRIEPPCIAGYVEHYWDC
SILLKHTHRRTVTQPH
>A0A7K7KE54|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Agelaius phoeniceus|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISVVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3B3U8Y0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia latipinna|TrEMBL
MDRQQIQVSDEEREVAREESRRRRRKKAITSASSTSMDQISVEFVLPTVARGGSSPDSLL
LEVAGNWTVEQVKAQVWMKAVSLNLCPDFYQRFCPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPTDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPNLYSMDPWVTRKPLPEHLLSKVNNGYILVVIHVSTSSQTIKVSID
DTPSQVDKYIGYCCFCLALREEYLYGEKALQSFNWIRQSLKNGEEIHLVLETPPDPELDL
VQREDWAQVDDCTGVAGTHEQLTIAEKDHERVFTISMWDCNRKFRVKVLGIDIPSLPKVP
EFMVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKIKDLPKGARLNLQVICGK
QPQTPNSKSSYHDNTSGRKTKNRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEESSS
SINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSREVGRDCGAGSEEGDGGERGQRE
MPNHLKKQFAAIVSTDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRWGKQEDVLA
THRLLDRSNAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQA
VKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGE
NMLQDFRKQVEMTEALQKVTREMKAMSADKYDVTQQVVIQLRQKLETLQLSGLPESFRVP
YDPGLRAGTLLIEQCKVMASKKKPLWLQFKRADPTTLSKDPVGIIFKDGDDLRQDMLILQ
ILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIATIQQSVVGSTGAFKDEI
LYQWLRDKCVSEEKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFG
HILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTNL
LIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQINW
FVHLVLGIKQGVEKRST
>G3W321|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sarcophilus harrisii|TrEMBL
MDLEDHDPVILREDNRGRRRKMKPQSAGMNLSSMEFIPIEFVLPTTHPLTKVAETVILEA
AGNCSVEQVKAQVWMQAVETSMTMEFYHQSSPEQFLLLYQKKEQWYEIYDKYQLIETLDC
VKYWKAFHKNMGQIHVVQRQPPTEETWAFQKQLNDLIDYDVTDMSNVHDDELEFTRRRLV
TPRIMEVASRDPKLYAMHPWITSKPLPTYLLKKIVNNCILIVIHRSTTSQTIKVSADDTP
GTILQSFFTKMAKKKSLMDIPESQNELDFVLRVCGRDEYIVGETPIKNFQWIRHCLKNGE
EIHLVLDTPPDPGQDEVRKEDWPLVDDCTGVTGYHEQLTINGKNHERVFTLSLWDCDRRF
RVKIRGIDIPVLPRNTELTVFVEANIQHGQQVLCQRRTTSKPFTEEVLWNVWLEFDIKIK
DLPKGALLNLQIYCGKAPSQSSKAAGSHEISSFEAKGKTQLLYYVNLLLIDHRYLLRHGE
YVLHMWKISGKGENQGSMNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPE
GDRVRGEMPNQLRKQLEEIIATDPLNPLTAKDKELLWHFRYESLKHPKAYPKLFSSVKWG
QQEIVAKTYQLLARREAWDQSDLDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHY
LLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEA
YLRGCGMAMLEDFTKQVQVIRLLQKVTIEIKSLSAEKYDVTSQVISQLKQKLENLQNSNL
PKSFRVPYDPGLRAGILMIEKCKVMASKKKPLWLEFKCADPTAQSNETIGIIFKHGDDLR
QDMLILQILRIMGSIWEAESLDLCLQPYGCISTGDKIGMIEIVKDAITIAKIQQSTVGNT
GAFKDEVLNHWLKEKCPIEEKFQAAVEKFVYSCAGYCVATFVLGIGDRHNDNIMITETGN
LFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQSPTFPQPTW
LLELN
>A0A1U7Q7Q6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mesocricetus auratus|TrEMBL
MCFSSMMPPAMADILDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEDKIQSLVGLSWIDWLKHTYPPEH
EPSVLENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNLTPIKINELAIQKRLTIHGKEDE
VSPYDCVLQVSGRVEYVFGEHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYAENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASGDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALNNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNRAFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRRDYRS
>A0A340X258|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lipotes vexillifer|TrEMBL
MKGDPEKRKSLEAHWVAEGMELENHEQHVVLREDNRRRRRRMKPRSVAASLSSMELIPIE
FVLPTSQRNTKTPETALLHVAGHGNVEQMKAQVWLRALETSVARDFYHRLSPDHFLLLYQ
KKGQWYEIYDKYQVVQTLDCLRYWKVLHRSPGQIHVVQRLAPSEETLAFQRQLTALIGYD
VTDVSNVHDDELEFTRRRLVTPRMAEVAGRDTKLYAMHPWVTSKPLPEYLLKKVTNNYIF
IVIHRSTTSQTIKVSADDTPGTILQSFFTKMAKKKSLMDIPESQDEQDFVLRVCGRDEYL
VGETPIRNFQWVRQCLKNGEEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTI
HGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSP
KPFMEEVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLL
YYVNLLLIDHRFLLRHGEYVLHMWQLSGKAEDQGSFNADKLTSATNPDKENSMSISILLD
NYCHPIALPKHQPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYE
SLKDPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVR
AIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRS
EIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSS
QVISQLKQKLEILQNLNLPQSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPT
ALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDRIGMIEI
VKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFV
LGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKK
TSRHFQQFQDVCVKAYLALRHHTNLLIILFSMMLMTEXXXXGMPQLTSKEDIEYIRDALT
VGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A7J8HUD3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rousettus aegyptiacus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYAHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K9EWC2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Baryphthengus martii|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVRFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVESPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNSGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYSVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEPPRGAAEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSIHHMKVLMKQGEALNKMKALNDLVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRS
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q3GE48|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Kryptolebias marmoratus|TrEMBL
MPPGKYGMQEEWEKEGGQEINMDFLLPTGIFLKFPVSRNETIRNIKKMVWKNARSEALYC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNAQISLL
IGKGLHEFEAQKNHEVDEFRNKMRTFCEEKAQERQSLPWQQWMEYSFPCDLEPCGSPPLY
GSVKSKNTKKLFVNVKFEACEESFMLQQDPQDLPVALMKSALKKRATVFRSVRLEPEDYT
LQVNGTMEFLYGNHPLRQFKYIFSCLRNGQNPQLIMVHHSTIIKYQEEQGRLCSQACKTR
SLSRPPPLPMKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWNQRLEFDMNVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPPLDKIIDTERNGDAVSTTKEEHMRLKEIMDNKNYTEFFEDEKELLWKLRTEV
RDYYPESLSKLLLITKWNKREDVVQMVSLLKHWPDLPAIHALELLDYSFPDPAVRSFTVR
CLRKLSDDELLQYLIQLVQVLKYESYLDCDLITFLLERALSNRRIGHFLFWHLRSEIHVA
SVSLRFGLILEAYCRGNIFHIKLLSRQNEALGKMKALSDIVKSGSQKMMVDDLKLCIRQE
SYKEALSDLLSPLNPSVILSEICADKCRFMDSKMKPLWLIYRNGTEQGDMVGIIFKNGDD
LRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKTGLIEIVKNSDTIANIQRNNSN
SAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERA
YKILCRNGTLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEDEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A8C8VF60|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pelusios castaneus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVILECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVYPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSTEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTAAPYMNGEASAKSLWAINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYITDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMTVIEDHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A812DXY7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sepia pharaonis|TrEMBL
MFNFSGTVTPNPAGKNATTLTIGFPSYNAKEKIIYPPKEVVLECAARNMEPEGTLGSPMW
RSNKIVMDQLSTILQQGPVNQMFEQDKELVWRLRHEVQHHYPESLALLLSSVKWSNYIDV
AKLQALLISWPRLNCELSLALLDFTYADKAVREFAVNCLEQLPDDEVTQYLLQLVQVLKF
EMYLYCPLVKFLLTRALRNRRFGHKLFWLLKSDMHDRQMNLRFSLILEVYCKSSQDHTTD
LIKQNEALLKIDAANMLIKNSTLALNDRKNKENLSADLRKVLCQNAYSMALSNLHSPLNP
LWNLKKLLVQKCKFLDSKMRPLWLVWENEELKENECHFSIIYKNGDDLRQDMLILQVIQI
VDFIWQEEGLDLRLNPYGCICTGRNTGMIEAVDAQTIANIQRKFDKASNRCVYEWLKEMN
PKKENLDKAVEEFTLSCAGYSVITYVLGICDRHNDNIMIKKNGQLFHIDFGHILGNTKKK
FGVVRDRVPFVLTNHFVTVIKNGEKPNDNFQRFQEICEKAYMTLRRRGTILITLFRLMIQ
SGLPELSSEKHVEYLQKSLALGVSDEEAIQQFNAKFKESLNKCWTTSLNWWFHMRVVDNT
>A0A812CJ28|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sepia pharaonis|TrEMBL
MPPSSGELWGLHLMPSQVDVDCFLPTGILVPLRCNRNATLESIKTDLWAEAKKFPFHTKL
LNPTCYIFVSITQEAEREEFFDETRRLCDLRLFLPWLKVVEPEGNRDEKKLNYEIGMAVG
ISINDFNEMKELEVMTFRRNILEVCKEVVACRDDPGGHNRALYTYPPEVESSSIPPSHVQ
SKLNKESDHVIVCIWVLSDNDDRQKYSVKVPHTATPQLVIAEAIRRRTRSMKLTADQQQM
CIRQFSNIYVLKVCGCNQYLLEEHPLSQYKYIRECIAREKIPQLMLQAKEAVYTAIPENI
FRMPTYVQKGVQALRDIDKQETIPIWTINTKLRIKINSAAYVNVKF
>A0A8C2Z504|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MPPAMTDLLDIWAAHSHLAGHALDKITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRAERLLD
SKIGVLISKGLHELDAINDQEVKDFRSKMFRLSEERMQQVQMMTCTEWLQACFSPQLEPP
AGTAITDGLNDRPADLKIIIHFDQSQVRVCSPGGETCIALMELALKKWLTTHGPEEEEAW
RGQYVLRVSHCLEFLCGDQPLIQYKYIRTCMQAKESPRLTLVHTSTVKAMFDKEISTIGA
VVGRKSSNPPLPLPPKRRVPTVSSVMCVCVQVRAGLFHGTELLCKPAVSSESSGRSDHTW
KDSTLEFDLSVCDLPRMTRLCFAIYAVMDKVKKQKSTKNAHINKYQTIRKAGKVHYPIAW
VNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATSLHINFPEYSS
HSIVFPPFDKILEKAAEIARASDCVSMGRGGKKFHIELKEIMERDPLSQLCENEKDLIWT
LRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVR
EYAVGCLRDMSEEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGNRKIGHFLFWHLRS
EIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKTARSKTKE
AMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGINVERCRYMDSKMKPLWIVYNNKL
LGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVV
SSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALERAIEEFTLSCAGYCVATYV
LGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTG
YTEKFGSFRQYCEEAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTD
EDALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C2ZSR4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
VELDDLPDDEEPKVLREDTRRRRRKKAISSSSGASMDQITVEFVLPTAARGGSGPDTLPL
EVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTL
DCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRRIELSDRDAKLYSMDPWVTRKPLPEHLLTKVSNAHVLMVIHIRTASQTIKVSIDD
TPAQVDEHGTDHSCSYVEMVEEYLYGDEPLQDFNWIRQCLKNGDEIHLVLEMPPDTDLDL
VQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVLGIDIPSLPKIP
EFIVFIEASIFHGQQLLAQERTSSKTFSEEVLWNCWLEFNIKIKDLPKGARLNLQVVCGK
QPLTPNSKGASTYQDNTAGTGKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEE
SSSSINADKLTSATNPDKASAMAVAILLDKYCYPVVLPKSRNAEGGERGQREMPNHLKKQ
FAAIVATDPLHPLSPEDKELLWHFRHECIRDPRAYPKLLGSVRWGRQEDVLATHRLLERS
SAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHD
SALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRK
QVEMTEALQKVTREMKAMSADKCDITAQVVFQLRQKLETLQLSGLPESFRVPYDPGLRAG
ALMIEQCKVMASKKKPLWLQFKRADPTTLSRDPIGIIFKDGDDLRQDMLILQILLIMESI
WETETLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFKDEILSQWLRDK
CVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKS
FMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMM
LMTGMPQLTSKEDIEYIREALTVGRSEDEAERHLLDQIEICREKGWMVQINWFVHLVLGI
KQGVEKRST
>A0A060WHW3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHEVFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKCPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGESSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNRETPCLELEFDYF
SSPVKFPDMTTVEGHANWXXXXXXXDNEQLRQVCNRDPLSEITEQEKDFLWRHRHYCVNI
PEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEK
YLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVS
QRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRR
PDYMDALQNFTSPLNPAHQLGNIRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIF
KNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCMSLGDCVGLIEVVRSSHTIMQIQ
CKGGLKGALQFNSSTLHQWLKDKNKGEMYDLAVDLFTRSCAGYCVATFILGIGDRHNSNI
MVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQ
EMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMK
QMNDAHHGGWTTKMDWIFHTIRQHALN
>I3MS63|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ictidomys tridecemlineatus|TrEMBL
IPLGIDCLMEFWTEEEKNHSVVVDFLLPTGIYLSFPVSYNANLSTIKQVLPGLLSNEPLF
HMLSDPKAYVFTCVNQTAEQQELEDEEQRLCDVRPFLPMLRLVTREGDHMEKLINSQISL
LIGKGLHEFDSLQDPEVNDFCTKMRQFSEETAARRQQLGLEAWLQYSFFLQLEPSTRSWG
DSNTSQIFNPDLLVNVKFEGSRESFTIQLSTKNVPIALIACALQKKTKVYQNLTMEQPED
YVLQVNGWHEYLYGSYLLCQFKVRSLLHSGLTPHLTMVHSSSILPSSVSQWSLGQPFCIE
LIQGSKINADEQMKLVVQAGLFHGNEMLCKTISSLEVSRMARLCFALYAVIEKAKKAHSS
NKKSKKDCPIAWANLMLFDYKDQLKTGELCLYMWPSVPDEKGDLLNPMGTVHSNPNTESA
VTLVIYLPEVAPHPVYYPALEKVVTWGAGGQLQLQGILEQRGSGELYEHEKDLVWKMQHE
VQEHFPEALAHLLLVTKWNKHEDVAQMLYLLCSWSELPVLNALELLEFSFPDFHVGSFAI
RSLQKLTDDELFQCLLQLVQVLKYKSYLDCELTQFLLDRALANQKIGHFLFWHHRTEMHV
PSVALRFGLIMEAYFRGSTYHMKVLMKQVEALSKLKALSGFVKVSSQKTTKPQTKELMHL
YMRQDTYLEALLHLQSPLDPSTMLAEVCVERCTFMDSKMKPLWFLYSSEEAGSAGSIGII
FKNRDDLCQDMLTLKMIQLMDALWKQEGLDLRWGLYPSPDDLLWLPIHGDCMGLIEAVQH
SDTIANIQLNQSNLAATAAFNKDTLLNWLKSKNPGSSPSEFTLSCAGYCVATYVQGIGDR
HSDNIMIRENGQLFHIDFGHILGNFKTKFGINRDNNEKFERFRGYCEQAYRILRRHGLLF
LQLFALMRAAGLPELSSSKDIHYLKDTLALGKTEEEGLKHFWVKFNEALSESWKTKVNWL
AHNLTKDNRQ
>A0A8C9SZI5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MPPAMTDILDIWAADSQLSNEDYVTVDFLLPTGIYIQMEVPREATIQHIKLLLWKQASTY
PLFAFLGEMESHMFECVNQSAVHEALEDETRRLCDVRPFLPVLKLVPRNCGRAERLNSKI
GTLIGKGLHELDALQDQEVKDFRVKMFRISEEKMQRVQMMTWMEWLQSCFSPQLENGVID
GLQEKLFDGALKVIMHFDQSQDTASLMVSPTITPRELTEQAVRKWITTHGPEEDESSCGE
FLLRVSNKLEFLYGEHPLIHYKHLGDDASNHLRAASRQQCAKPPCVFPIRTVRASDLGCP
LPVCAQVQVRAGLFHGTELLCKPSVSTESSGRSEHVWNHTLDFDIAVCDLPRMARLCFAI
YAVMDKVKKQKSTKNGSCHHYPIAWVNTMVFDYRGHLKTGDNILHCWSSFPDELEEMLNP
IGTVRTNPYTENATALHIYFPEYSSCPVILEKAAEIARSSDCLPMVFHIELKEIMERDPL
SQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDAL
ELLDFNYPDQYVREYAVRCLKDMSDDELSQYLLQLVQVLRYEPYYDCALTRFLLERAQTN
RKIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKAVNELIK
LGTIKNARKTKEAMLTKEAMLTCLRQTGFTETLSDLHSPLNPSVVLSGINVEKCRYMDSK
MKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCL
ATGDRSGLIEVVSAAETIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTH
DFIHVIQQGKTGNTEKFGNFRQYCEDAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQ
YLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAHNRS
>A0A8C9WLK1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MEVPREATIQHIKLLLWKQASTYPLFAFLGEMESHMFECVNQSAVHEALEDETRRLCDVR
PFLPVLKLVPRNCGRAERLNSKIGTLIGKGLHELDALQDQEVKDFRVKMFRISEEKMQRV
QMMTWMEWLQSCFSPQLENGVIDGLQEKLFDGALKVIMHFDQSQVRMVSAESLMVSPTIT
PRELTEQAVRKWITTHGPEEDESSCGEFLLRVSNKLEFLYGEHPLIHYKHLGDDASNHLR
AASRQQCAKPPCQMHTCVWDAQTQFKIVLVKGSKVNAEETAKVQVRAGLFHGTELLCKPS
VSTESSGRSEHVWNHTLDFDIAVCDLPRMARLCFAIYAVMDKVKKQKSTKNGSCHHYPIA
WVNTMVFDYRGHLKTGDNILHCWSSFPDELEEMLNPIGTVRTNPYTENATALHIYFPEYS
SCPVVFPPFDKVRTVTHPCGEREPCKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCR
ENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVRC
LKDMSDDELSQYLLQLVQVLRYEPYYDCALTRFLLERAQTNRKIGHFLFWHLRSEIHMPA
VSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKAVNELIKLGTIKNARKTKEAMLTKEA
MLTCLRQTGFTETLSDLHSPLNPSVVLSGINVEKCRYMDSKMKPLWIVYNNKLLGGDTLG
IIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSAAETIA
NIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGN
FRQYCEDAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQF
RQKFDEALRESWTTKVNWMAHNVAHNRS
>A0A8C9TXK5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MAPGVYCLPNMWEGGVQQVKMDFLLPTGIYLSFGVSGNDTIGAIKKTLWRNAKNEPLFFA
LSDPDAYVFTCINHTAEQEELEDEQRRLCDVRPMMPILRLVAREGDRVEKLITSQISLLI
GKGVHEFDTMKNHEVNEFRTKMRTFCEELAMDRQRLPWQKWIEYSFPCDLEPCALLSHSG
NLRNRASKKIIVNVKFEASDESFTLQVEPQEVPLTLMKSALKKKATVFRPMKQEKPEDYA
LQVNGRWEFIYGNFPLCQFKVNDSLPRAMNYLPPVSKQQTMSSLWSIQDAFSIHLMHGSR
VNADEGMKLVVQAGLFHGSELLCKVVTSSEVNVCSEPVWDQKLEFDINVCDLPRMTRLCF
ALYAVIEKSKKPRSTKKKNKKADCPLSWVNTMVFDYKDQLKTGEYYLSTWPSVPDDKTDL
LNPMGTVEINPNTDSAAGLLIRFQNVRPHPIYYPSLDKVSWTVRSLNCPRMLQFLRLLLH
GNIYLYNHLKVSEIVENKNYTEFFEDDKEILWKLRYEVREKYSESLSKLLLITKWNKHED
VAQMVSLLQKWPDLPALHALELLDYSFPDRNVRSFTIRCLRKLSDDELFQYLLQLVQVLK
YESYLDCDLTKFLLERALSNKKIGHFLFWHLRSEMHVPSVNLRFGLILEAYCRGSIYHMK
TLMKQNEALNKMKSLNDFVKSASQKGTRTQTTGEMKKCIKQETFMEALSDLLSPLNPSLI
LSEICPDRCKYMDSKMKPLWLVYKNEKVQGDPLGIIFKNGDDLRQDMLTLQMIQLMEILW
KKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKS
KNPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKS
KFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYKILCRNGTLFVNLFALM
RAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMVHSVSKD
NR
>A0A8C3BX47|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cairina moschata domestica|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C3BZ00|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cairina moschata domestica|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDAEALSAEKRESFANVPVAASSGLIVFRTYHKYYLE
E
>A0A7L2NVE0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pycnonotus jocosus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELLPIEFILPTSNKHTKAPETMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C5R6L5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptobrachium leishanense|TrEMBL
MELDNNDQPVVLRDENKRRRRKMRPHSATINIFSMELIPIEFILPTSHKNNKAPDTILLE
IAGNCTVEQMKAQVWMNAIEKSHNSDFYHRLAPDQFLLQYQKKGQWYEIYDKHQVIQTLD
CIVYWKVLKKTVGKIYVVQKEKNSDETLEYQKQLNYLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIELAKRDARLYSMDPWVTSKFLPEYLGRKISSNTIFIIIHKGMTSHTVKVSINDT
PDEILQSFFTKMAKKKSLLDISEENSELDFVLRVCGRDEYIFGNTPIKDFHWIRQCIKNG
DEIHLVLDAPPDPTDDKVQKEEWPLVDDCTGVTGYHEQLTIEEKDHEKIFTISLWDCNRK
FRVKVIGIDIPVLPRNSELTVFVEANIQHSQQLLAQKRTTSKPFTEEVLWNTWLEFDIKI
KDLPKGALLNLQIFCGKAVTPSNKTSLQSPDSSSSDSKCKNQLLYYVNLLLIDHRFLLRQ
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKDTSMAISISLDKYCHPVALPKNKSVVD
AEQDRSRGEMPNQLRKQLEEIMATDPLHPLTPEDQELLWHFRYEIIKHPEAYPKLFTSVK
WGQQEIVTKTYQLLSKREAWDDCSLDVGLTIQLLDCNFSDENVRAMAVQKLDSLPDDDVL
HYLLQLVQSKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGTAMLKDFMKQVQVT
ELLHKVTMEIKSLSAEKYDVTSQVITQLRQKLEKLQGSKLPESFRVPYDPGLRAGLLMVE
KCKVMASKKKPLWLEFKCADPTALTNETIGIIFKHGDDLRQDMLILQILRIMGSIWEAES
LDLCLLPYGCISTGNKIGMIQIVKDATTIAQIQQSTVGNTGAFKDEVLSQWLKEKCPLEE
KYNAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGIN
KERVPFVLTPDFLYVMGTSGKKTSLYFHKFQDVCVKAYLALRHHSNLMIILFSMMLMTGM
PQLTSKEDIEYIRDSLTVGKNEESAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVE
KHSA
>A0A7K9TBA0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Galbula dea|TrEMBL
MPPGIFCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRVKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPLAKGLGT
GPLHTPSKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
YPVYYPSFEQLLELGRNGEQPRATAEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C3LTM1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysolophus pictus|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHTY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
NFQDKLYSGNLVVAIHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEIDPAD
YVLQVSGRLEYVFGDHPLIQFQYIHNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEVAIN
RKSSNLPLPLPPKKTRATTSVWDICSPFKIILLKGNKLNTEENAKVHVRAGIFHGTELLC
KTIVSSEISGRSDHAWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKSMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLRNGEFVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCKYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8B9ZXG4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas zonorhyncha|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GLLHTPTKNIFVNVKFQSGGESFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANTPKMS
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPNVAS
HPVYYPSFEQLLELGRNGEPPRTQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYP
QALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKL
TDNELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALR
FGLILEAYCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCMKQET
YLEALSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIFKNGDDL
RQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNM
VATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRET
GQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAY
MILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALR
ESWKTKVNWLAHNVSKDNRQ
>A0A087VDW5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balearica regulorum gibbericeps|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTADFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKTQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C3KC96|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calidris pygmaea|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSSELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNHSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C3KFQ6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calidris pygmaea|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMTKGLGA
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARL
CFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKG
ELLNPMGTVQCNPNTESAAALVICFPSVASHPVYYPSFEQLLELGRNGDQPRQKLQLKEI
LERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQSWPEL
PVLNALELLDFSFPDRYGDCEQDNELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRK
IGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKAS
SQKATKPQTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIV
FNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTG
LIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYC
VATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQ
QGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLA
LGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6J8CL11|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mytilus coruscus|TrEMBL
MPPSSGELWGHHLMPSTIQVDCLLPTGIIIQVDVSRDETLERIKADLWVKAKLYPLYERL
LEPASYIFVSITQDARKEEFYDETRRFCDLRLFQPILKIVEPVGNREEKMLNFEIGVTIG
VSINEFNEMKDLEVMTFRRNILDICKNAIEDRQRRGKASEALYAYPPDIESSPILPSHLQ
TKIKEMKNDVVACVWVVSEDNSRSKFSVKVPHDAYPIDVIAGTIRRRSRMMGISKEHAER
CIEEYSDTYALKVCGCDQFLLEEHPLSQYKYVRECIARDNIPQFMLLTKESLYAAISPNV
FITPSYTQKGMQLLTEINQQKTLSLWEIHAKLRIKILCATYVNVKELGKIYVKAGIYHGT
EALCEFQDTKLVDSNNPQWHEWLEFLYIQDLPRSAKLCLSICYTSKKRREPLSLGWANLQ
LFDFNDRLMNEKVSLNLWPLPQGMDDLLNYVGLPGSNPDQETPCLEIEFDRLSHPVSYPP
EKQIEDLALYAIGKESPLIYLDTPQIQTKERAMVDDITSRDPLSEISEQEKDILWKLREY
CIQVPQSLPKLLQSVKWNEREYVAQLYMLLRRWPRLMPEFAMELLDCSYPDLCVRQYAVT
CLDHGFSDDKLQQYMLQLVQALKFEPYLDSPITRFLLKRALQNQKTGQLFFWHLKSEIHN
TSIQLRFGLVLEAFCRGCGSNLKMLLRQVEALDKLTKLTNMIKNEVKDDINEIMKFLANQ
LQQPDYQDGLKNFLSPLDNSHILGDLDISHCSVMTSKKKPLWLVFSNPDVMADIWFTDYK
LIFKNGDDLRQDMLTVQLFKIMDTLWKNEGLDLRLIPYSVISTGKDVGVIEIVRDSSTIM
SIQQKNGIRAAVQMDSLGLYNWIMYHNKDREEQAISNFTRSCAGYCVATFILGIKDRHSG
NIMVRKNGQVFHIDFGHFLDHRKKKFGITRERVPFVLTMDFIRVIARGSDQPLKHKEFKK
FQQLCCEAYLIIRKNAYLFINLMTMMLSCGIPELQSLDDISYLRKTLAVEEKDDEKALKY
FIAKFNSAYSDAWTVKTDWLFHYMKNR
>A0A3Q2H9K0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Equus caballus|TrEMBL
MCFNFMMPPAMADSLDIWSVDSQIVSDGSIRVDFLLPTGIYIQLDVPREAPISYIKQMLW
KQVCDYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRVKMRKFSEEKIQSLVGLSWMDWLQQTYPPEH
EPSNLENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIRGKEDE
VSPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVNCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYTNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRTLLP
>A0A672MK37|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQS
GKSHSGKKILVNVKFEGSEETFVLQQDPQDLPMFLKRNALRKKSNVFRPAKQEKPEDYTL
QVNGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKFQEEQGGLSNQVSRTRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKVKLLILFTCFIRSVLWVYW
KSLLLWLEYLDCPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPN
IDSTAGLLIRFPNIRPHPLYYPPIEKLNELGMNGEKVVATKEEHLKLREIVDNKNYTEFF
EDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVGLLRKWQDLPAIHALELLD
YSFPDPHVRSFTIRCLGNLRNDELFQYLLQLVQVLKYESYLDCDLTCFLLERALSNKKIG
HFLFWHLRSEMHVPSVSLRFGLILEAYCRGSIFLIKSLMKQNEALNKMKALNDFVKSGSQ
KATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYK
DKYDHVGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRDKLDQAIEEFTLSCAGYCV
ATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQE
GRTNNSEKFERFREYCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLAL
GKSEEEALKNFKVKFNEALRESWKTKVNWMMHSFAKDNR
>G3SNN8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Loxodonta africana|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLV
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWEAWLQYSFPLQLEPVARGWGA
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQQLVERPEDYA
LQVNGKYEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAAQVQKLR
TKPPPIPVKKPSSASLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVSVCSGPVWNQRLEFDISICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLFMWPFVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
HPVYYPALDKVSLGQDLGWVGPPYQDLPCPEPMGSKGNFQGPASEQGLCHPMSCPALVGG
VGGVTMHSGGVPDFLESSLALEQRFSTRAILTTPPGCWTSAPRPHVGSFAIKSLRKLTDD
ELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPAVALRFGL
IMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVQLSSQKTTKPQAKEMMHMCMRQETYLE
ALSHLQSPLDPSTLLADVCVEQCTFMDSKMKPLWIMYSNEEAGSEGSVGIIFKNGDDLRQ
DMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAA
TAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQ
LFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTI
LRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRES
WKTKVNWLAHNVSKDNRQ
>A0A672LDE5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDGTRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYSMPLEAGSLE
NLIDKHEGIIKITMHYDQSQVSSVNLVLSLHCTVTELMDQALKKWQTTHCPEEDIGFRSD
YVLRVSGKLEFLFEDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIGSVLA
RKTSNPPLPLPPKKRLPTASTLFPALQLMQGVLSFAYLAVRAGLFHGTELLCKTAVSSES
SSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIPWVNT
MVFDYRGQLKTGDIILHCWTSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPV
VFPAFDKGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSV
KWSKHEDMTQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVYCLRDMSDDELLQYLL
QLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMFMPAVSVHFALILEAYCR
GCIPHIEVLKKQVEALSKLKAVNELIKFGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDL
HSPLNPNILLAGINVERCKYMNSKMKPLWIVYNNKLLEGDTVDIIFKNGDDLRQDMLTLQ
ILRLMDLLWKEAKLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNK
DALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDF
GHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGN
LFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVN
WMAHIVAHPS
>A0A226PET1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Colinus virginianus|TrEMBL
SRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPVTKGL
GAGLLHTPIKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPED
YTLQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQISSIANTPK
MAVKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQLLELGRNGEQPRTAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMR
HDIRDQYPQALAKLLTITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSF
AINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEM
HVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNELVKLSSPKATKPQAKEMM
HVCMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGI
IFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIAN
IQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERF
RGYCEKAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFR
LKFNEALRESWKTKVNWLAHNVSKDNRQ
>G3NQ48|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gasterosteus aculeatus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHVLDQVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPSLGEMESHMFECVNQAAVHEELEDESRRLCDVRPFLPVLRLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRLSEERMQKVQMMTCTEWLQACFSPQEGLN
DRPADLKVIIHFDQSQDSASLKVASSCVPSELMEQALKKWLTTHGPEGGEEEEAWRGQYV
LRVSHCLEFLCGDQPLIEYKYIRSCMQAKEPPHLTLVHASNVKVLFDKEISAIGAVVSRK
SSNPPLPLPPKRRAPTTCVWDVSQPFKIVLVNGSKVNAEESAKVQVRAGLFHGTELLCKP
AVSSESSGRSDHTWNNSTLEFDLSVCDLPRMTRLCFAIYAVMDKVKKQKSTKNLHTNKYQ
TIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPVQLREMLNPIGTIQTNPYTE
NATALHIHFPEYMSHSVVFPPFDKILEKAAETVKPNDLMSRGWKKFNIELKEIMERDPLS
QLCENEKDLIWTLRHDCKDYFPQSLPKLLLSVKWSKHEDMAQQLQALLQVWPKLSPRDAL
ELLDFNYPDQYVRKYAVGCLRDMSEEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGN
RKIGHFLFWHLRAEIHMPAVLVQFALILEAYCRGSIHIEILKKQVEALSKLKSVNELIKL
GTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNILLSGINVEKCRYMDSK
MKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCL
ATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALERAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTH
DFIHVIQEGKTGYTEKFASFRQYCEAAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQ
YLKDSLALGKTDEDALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A091WH84|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Opisthocomus hoazin|TrEMBL
TMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLY
QLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGF
AIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPK
HIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQL
KLCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPL
DTFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTG
IYHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEH
CPLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDW
FSNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDP
LSEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAM
ELLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDIL
KQEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C6H420|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus spicilegus|TrEMBL
MPPGVDCPMEFWTKEESQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLRVSNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYA
LQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGRITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQLSQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAI
KSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHV
PSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHM
CMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGII
FKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANI
QLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFR
GYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRV
KFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L1INY8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Smutsornis africanus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
TKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q3S6Q1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGQI
IVVIWVIVSPNNDKQKYTLKINHDSVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQGKY
ILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYSQLPTDNFVMPSYSRR
ISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQMCDN
VNTQRVPCSNPRWNEWLTYDMYISDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLF
DYTHTLVANKMALNLWPVPHGLEDLLNPIGITGSNPNKETPCLELEFDHFSSPVKYPDMN
AIEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPLSEITEQEKDF
LWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAMELLDCNYPDPM
VRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWH
LKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKV
QMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMS
ELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEV
VRSSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDMAVDLFTRSCAGYCVATFI
LGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQE
CTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEK
SEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A7N8X8C2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSRNDTIKVIKKLVWKNARSEALFT
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTRMRQFCEEKSQERQMLPWQQWMEYSFPCDLEPCCSLPST
KSRNTKKIFINIKFEACDVSQDPQDLPVALMKSALKKKATVFRSVRLEPEDYTLQVNGSW
DFIYGKHPLRQFKYIFSCLRNGQNPHLIMVHRSTISKHQEEQERMCNQVYKSRSQSRPPP
LPLKKVRALTRTEQHFHLCFSAISLSFITTVLVVQAGLFHGSELLCKVVTSSEVTVCSEP
LWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKPFYLYITARKEGIAWV
NTMVFDYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFPNIRPH
PLYYPPLEKVLTPYKLKEIMDNKNYTEFFEDEKELLWKLRYEVCSLYPESLSKLLLITKW
NKREDVVQMVGLLRNWPDLPAIHALELLDYSFPDPAVRFFTIRCLKKLSDNELLQYLIQL
VQVLKYESYLDCDLTTFLLERALANRRIGHFLFWYLRSEIHVASVSLRFGLILEAYCRGN
IHHIKLLTKQNEALGKMKILSDIVKQESYLEALSDLLSPLNPSIILAEICAHKCRFMDSK
MKPLWLMYGNPWAQGEMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMSPYGCL
STGNKMGLIEAVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFT
LSCAGYCVATYVLGIGDRHNDNIMIRENGQLFHIDFGHFLGNFKRKLGINRERVPFILTY
DFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGMLFVNLFAMMKAAGLPELSSFKDIQ
YLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A672HFV6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salarias fasciatus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKIFYTILSSFFFSPKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLKMCVQEYQG
KYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMDNFTMPSYA
RRISTATPYMNGETATKCLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGIYHGGEQLC
DNVNTQRVPCSNPRWNEWLNYDMYIPEIPRAARLCLSICSVKGRKGAKEEHCPLAWGNIN
LFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSCPVKFPD
MTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNDQLRQVCNRDPLSEITEQEK
DFLWRHRHDCTNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNFPD
PMIRDFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFF
WHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLKQEKKDEAQ
KVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWENPDM
MSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLI
EVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRSCAGYCVAT
FILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGT
QECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLAL
DKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQQGQNA
>A0A2K8FKT1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSAQTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARL
CFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKG
ELLNPTGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKILELGRHSECVHVTEEEQLQ
LREILERRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCS
WPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELT
KFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALS
KLKALNDFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCT
FMDSKMKPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRM
TPYGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDR
AIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERV
PFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELS
CSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q2WVF3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Haplochromis burtoni|TrEMBL
MDRQQIQVSDEECQVPREESRRRRRKKAITSSCSTSMDQISVEFVLPTAARGGSGPDTLQ
LDVAGNWTVEQVKAQVWMKAVTSNLCPEFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTRKPLPEHLLSKINNGHILVVIHIGTASQTIKVSID
DTPTLVLASFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLK
NGEEIHLVLEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNI
KIKDLPKGACLNLQVICGKQPQIPNSKGSSYQESTAGSSCLDGKTKSRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSCSINADKLTSATNPDKASSMAIAILLDKYCYPVVLP
KSRDVGRDWAVGGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHE
CMRDPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVR
SMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSKHYQQRYAVLLEAYLRGCGENMLQDFRKQVDMTEALQKVTREIKTMSADKYDVTP
QVVFQLRQKLENLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADST
TLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKK
SSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSE
DEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A3B5PW38|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xiphophorus maculatus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
NFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDGINDQEVKDFRSKMFRLSEEKMQRVQMMTCDEWLQACFSPQLEPA
ALTTITDGLNDRPADLKVIIHFDQSQDSTSLKVLSSSTPSELMEMAVKKWLITHAPEEEE
WSGQYVLRVSHCLEFLCGDHPLIQYKYIRTCLQAKEPPHLTLVHTSTIKELFDKEMSAIS
AVVSRKSSNPPLPLPPKRRIPTQAQTCVWDVTSSFRIVLVKGSKVNAEESAKVQVRAGLF
HGTELLCKPAVSSETSGRSEHTWRDNALEFDISISDLPRMTRLCFAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSPYPIVFPPFDKILEKAAQIARASDSMSIGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLCPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAERNRKIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALT
KLKSVNELIKLGTLKNARSKTKEAMLTKEAMITCLKQSGYSEALSDLSSPLNPSVLLSDI
SVEKCRYMDSKMKPLWIVYNNKLLNGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAN
LDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTNCNVAATAAFNKDALLNWLKERNSG
DALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEDAYLILRKNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A3Q2VRF8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Haplochromis burtoni|TrEMBL
MDRQQIQVSDEECQVPREESRRRRRKKAITSSCSTSMDQISVEFVLPTAARGGSGPDTLQ
LDVAGNWTVEQVKAQVWMKAVTSNLCPEFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTRKPLPEHLLSKINNGHILVVIHIGTASQTIKVSID
DTPTLVLASFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLK
NGEEIHLVLEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNI
KIKDLPKGACLNLQVICGKQPQIPNSKGSSYQESTAGSSCLDGKTKSRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSCSINADKLTSATNPDKASSMAIAILLDKYCYPVVLP
KSRDVGRDWAVGGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHE
CMRDPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVR
SMAVRKLETLEDDDVLRYLLQLVQSKRIGHFLFWFLRSEIAQSKHYQQRYAVLLEAYLRG
CGENMLQDFRKQVDMTEALQKVTREIKTMSADKYDVTPQVVFQLRQKLENLQSSGLPESF
RVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADSTTLSKDPIGIIFKDGDDLRQDML
ILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIANIQQSVVGSTGAFK
DEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHI
DFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQ
INWFVHLVLGIKQGVEKRST
>M3ZWR1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xiphophorus maculatus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
NFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDGINDQEVKDFRSKMFRLSEEKMQRVQMMTCDEWLQACFSPQLEPA
ALTTITDGLNDRPADLKVIIHFDQSQVRVRHIFFSHIDIIKSLMEMAVKKWLITHAPEEE
EWSGQYVLRVSHCLEFLCGDHPLIQYKYIRTCLQAKEPPHLTLVHTSTIKELFDKEMSAI
SAVVSRKSSNPPLPLPPKRRIPTVSPVQLWTIVLSFQIVLVKGSKVNAEESAKVQVRAGL
FHGTELLCKPAVSSETSGRSEHTWRDNALEFDISISDLPRMTRLCFAIYAVMDKVKKQKS
TKNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPI
GTIQTNPYTENATALHIHFPEYSPYPIVFPPFDKILEKAAQIARASDSMSIGRGGKKFHI
ELKEIMERDPLSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQ
IWPKLCPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCAL
THFLLERAERNRKIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEAL
TKLKSVNELIKLGTLKNARSKTKEAMLTKEAMITCLKQSGYSEALSDLSSPLNPSVLLSD
ISVEKCRYMDSKMKPLWIVYNNKLLNGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEA
NLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTNYGVEIDALDRAIEEFTLSCAGYC
VATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQ
QGKTGNTEKFGSFRQYCEDAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLA
LGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>U3IZV1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos platyrhynchos|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKSNRIARDNELRE
SDKEQLRAICTRDPLSEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYC
LVKDWPPIKPEQAMELLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYL
DNQLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQ
VEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLR
LEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQ
NQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKN
KGEMYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKF
GYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMM
LGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQH
ALN
>A0A8B9WC11|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus grunniens|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFE
>A0A7K6F960|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Daphoenositta chrysoptera|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKAA
SKPPPLPKKKPNYGSLWALEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAGPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRYGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A091VS60|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nipponia nippon|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSSELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSVMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C0TWE4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNDFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPNDYVLQVSGRVEYVFGDHPLIQFQVHVRAGLFHGTELLCKTIVSSEISGKNDHIWNE
PLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKNINPCKYQTIRKSGKVHYPVAWVNT
MVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIKFPENKKQPY
YYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQ
DCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYA
VGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVH
IPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNKAKGKEAMH
TCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVI
FKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADI
QLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSD
NIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFR
QCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQ
KFDEALRESWTTKVNWMAHTVRKDYRS
>A0A5N3WE79|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Muntiacus muntjak|TrEMBL
MCFYFMMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISCIKQMLW
KQVTNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPEL
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMSRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIILVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKSDHIWNEPLEFDINTCDLPRMTRLCFAVYAVLDKVKTKKSTKTM
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRCGDITLHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPHALPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C4ICT0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MPPGKYGMQEEWEKEGDQGILMDFLLPTGIFLKFPVSRNDTIKSIKKVCPHTQSEALFSG
LGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRVEKLTNTQISLLI
GKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPMSG
SMKSKSTKKIFINVKFEACDESFMLQQDPQDFPVALMRSALKKKATVFRSVRQEPEDYTL
QVNGRWEFIYGKHPLCQFKYIFSCLRNGQNPHLTMVDHTTISKYQEEQGRMCSQVYKSRS
LSRPPPLPLKKNTSSLWSINEPFYINLVQGSRVNADEGMKLVVQAGLFHGSELLCKVVTS
PEVAVSSEPLWDQNLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFHNIRP
HPLYYPPLDKISDVEKNGDAGIPTKEEYMKLKEIMDNKNYTEFFEDEKELLWKLRTEVRN
HYPESLSKLLLITKWNKREDVVQMVSLLRKWPDLPAIHALELLDYSFPDPAVRSFTIRCL
RKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLSSEMCVFNE
ALGKMKALSDFVKSGSQKMTVDDLKLCIRQESYLEALSDLLSPLNPSIVLSEICADKCRF
MDSKMKPLWLLYKNPQAQGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIP
YACLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDQAI
EEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPF
ILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSF
KDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A834A9Y5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phyllostomus discolor|TrEMBL
MPPGVDCPMEFWTSEENQNVAVDFLLPTGVYLNFSVSRNANLSTIKKALWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYCFPLQLEPSARTWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDMPLALMTCALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHRGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGEYCLYMWPSVPDEKGELLNPTGTVCSNPNTESAAALIICLPEVAP
YPVYYPALDKILELGRHGEHGRFTEEELTPLRPQQLQLREILERRGSGELYEHEKDLVWK
MRHEVQERFPEALARLLLVTKWNKHEDVAQMLCLLCSWPELPVLSALELLDSSFPDRHVG
SFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRS
EMHVPSVALRFGLIMEAYCRGSIHHMRVLMKQGEALSKLKALNDFVKVSSQKTPKPQAKE
LLHVCMRQETYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVMYCNEEAGSNGS
VGIMFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDT
IANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGD
RHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKF
ERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALK
HFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A673ZF38|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPAMPDDLDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFCPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQACFSPQLEPGGG
ATPLTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSSVQAMFEKEISA
IGAVVNRKSSNPPLPLPPKRRGPSLSRSPYYGEPLVVVVPPPQVQVRAGLFHGTELLCKP
VVSSESSGRSEHVWNRTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKSTKNAHINKYQT
IRKAGKVHYPVAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPIGTIQTNPYTEN
STALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCSTMVLRGGKKFHIELKEIMERDP
LSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDA
LELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLNRAQC
NRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELI
KLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMD
SKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYG
CLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
THDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTSVKD
IQYLKVSLSKIMYTDDEALRESWTTKVNWMAHNVVKDNRS
>A0A673ZH23|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPAMPDDLDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFCPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQACFSPQLEPGGG
ATPLTDGVNDKQAEASLKVTITSPSELMEQALRKWLTTHGPEEEGRQAEQYVLRVSDKLE
FLCGDHPLIQYKLSRSPYYGEPLVVVVPPPQVQVRAGLFHGTELLCKPVVSSESSGRSEH
VWNRTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKSTKNAHINKYQTIRKAGKVVLMFL
CPPDELEEMLNPIGTIQTNPYTENSTALHIHLPDYNPHPILFPPFDKSRGGKKFHIELKE
IMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPK
LSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFL
LNRAQCNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLK
SVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVE
KCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDL
RIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDAL
EKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRE
RVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPE
LTSVKDIQYLKVIGRFTWDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKD
NRS
>A0A8J4LET9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aptenodytes patagonicus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEERGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C3TEV1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelydra serpentina|TrEMBL
MELGNYEQPVVMREENKRRRRRMKPYSAASNLSSMEQISIEFILPTFNKHTKVPETMLLE
IAGNCTVEQMKAQIWIRAVEMSQTTDFYHKFAPDQFILQYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGKIYVVQKQKPTEAVQEFQTQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYSMHPWITSKPLPEYVFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGEMPVKDFHWIRQCLKNG
EEIHLVLDDPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIVGIDIPVLPRNTELTVFVEANIQHGQQLLSQRRTTSKPFTEEVLWNTWVEFDIKI
KDLPKGALLNLQIYCGKAQALSTKVSLQSHDSPNSDSKCKTQLLYYVNILLIDHRSLLRS
GEYVLHMWKISGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEAIVDTDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKREAWDHSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQIIKLLHKVTMDIKSVSAEKPAPLPLEPRYRGHLPPSLRPP
RPSAPSPRIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILR
IMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEILNQ
WLKDRCVIEEKFQAAVERFVYSCSGYCVATFVLGIGDRHNDNIMITESGNLFHIDFGHIL
GNYKSFLGINKERVPFVLTPDFLFVMGTAGKKTSLHFNKFQDICVKAYLALRHHTNLLII
LFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKHFLDQIEVCRDKGWTVQFNWFLH
LVLGIKQGVEKHSA
>G7NU51|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca fascicularis|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPFSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDIHICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFLHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8J8XAB5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca fascicularis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A6J1UPS5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Notechis scutatus|TrEMBL
MQTACGMELETSDQAVVMRDDNKRRRRRRMKPYCTANTLSSTELISIEFVFPTTSIVLDI
PTNCTVEQMKTQVWMRAVEGHQTSDLFRKITPDQFLLLYQKKGQWYEIYDKYQIIQTLDC
ILYWKVLQKKVGKIHVVEKPNPSDEVQDFQNQLNYLIGYDVTDVSNVHDDELEFARRRLV
TPRTIEVSCRDPKLYSMSPWTTSKPLPEYLLSRIANSNIFINIHRGTTSQKIKVAVDDTP
DVILQSFFTKMAKKKSLMNIPEDYSEQDFVLRVSGRDEYIVGETPIKNFHWIRQCLKKGD
EIHLVLDEPPDSNQDEVQKEEWPLVDDCTGVSGYHEQLTIHGKDHERVFTISLWDCNRKF
RVKIIGIDIPILPRNTDLTVFVEANIQHSQQLLSQRRTTAKPFTEEVLWNVWLEFDIKIK
DLPKGALLTLQIYCGKTPLPSTKGNLHPQDSPSTDPKYKTQLLYYVNLLVIDHRSLLRTG
DYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHKIASDP
PEGRARVEMPNQLRKQLEEIIATDLLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKW
GEQKLVTETYQLLAKREAWDQSALDVGLPIQLLDCNFSDETVRTMAVQKLEGLEDDGVLH
YLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILE
AYLRGCGKAMLKDFLRQVQVTELLHKVTREIKAISAEKYDITPQVIAQLKQKLERLQDNK
FPECFRVPYDPGLKAGALMIEKCKVMASKKKPLWLEFKCADPTSLSSETIGIIFKHGDDL
RQDMLILQILRIMASIWEEESLDLCLLPYGCISTGNKIGMIEIVKDANTIAKIQQSTVGN
TGAFKDETLNQWLKDKCVIEEKFQSAVERFVYSCAGYCVATFVLGIGDRHNDNIMITGSG
NLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLRFQNFQDICVRAYL
ALRKHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKHEEDAKKYFLDQIEVCRDK
GWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6P6IAN1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Puma concolor|TrEMBL
MELDNYEQPVVLREDNRRRRRRMKPRSTTASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVATDFYRRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQIHLVQRRAPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCSKAPVLAGKTSAETPSSESKGKTQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTDQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKEATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A091I3Y5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Buceros rhinoceros silvestris|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMILLE
IAGNCTVEQMKAQIWMHAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTSRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITPD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLEGLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVVEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCIIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGESEEGAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C8BLM4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Otus sunia|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLERSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K8KLR7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ardeotis kori|TrEMBL
MPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLRLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPSLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVHDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPTARSLGT
GSLPTPSKNIFVNIKFQSGGESFTFHISPKEFPITLMSYAIKKQATVFRHETLDNPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQSRTALEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFNFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMRSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEHAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRD
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C7ZWV4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias sinensis|TrEMBL
MHPGIYGMLEEWEDGDQEINMDFLLPTGIFLKFPVSRNDTIKHIKEMVWRNARSEALFSG
LGDPDGYVFTCINQTAEREELEEEFRRIRDVKPFMCVLRLVAREGNRQEKLTNTQITQLI
GKGLHEFESQKNHEVNEFRTKMRTFCEEKALERQYLPWQRWLEYSFPCDLEPCRTPSGFG
SVKLKSSKIFINVKFEASDESFMLQQDCQDLPVALMKSALKKKATVFRSLRQEPEDYILQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPQLTMVHHSTVSRFQEEQSRMCNQMFKSRSL
SRPPPLPLKRQNTSSLWSINEPFYIQLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTS
LDVTVCSEPLWDQRLEFDINVCDLPRMSRLCFALYAVIEKTKKPKSTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSMWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRP
HPLYYPSLEKIIDFEKNGDVACTHKEEHLKLKEIMDNKHYTEFFEDEKDLLWKLRTEIRE
HYPENLSKLLLVTKWNKREDVVQMVSLLKKWPDLPAIHALELLDYSFPDPAVRSFTVRCL
RKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASV
SLRFGLILEAYCRGNIHHIKILNKQNEALAKMRALSDFVKSGSQKMTVEDLKLCIRQETY
MEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNPSTPGDMVGIIFKNGDDLR
QDMLTLQMIQLMENMWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQLNSSNSA
ATAAFNKDALLNWLKSKNPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYK
ILCRNGMLFVNLFAMMKAAGLPELTCFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDNRA
>Q9PTE5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus laevis|TrEMBL
DETRRLCDLRLFQPFLKVVEPVGNREEKILNREIGFAIGMPVCEFDMVKDSEVQDFRKNV
LNVCKDSVELRDANGPISRALYVYPPNVESSSELPKHIESKLDKGQIIVVIWVIVSPNNE
KQKYSLKINHDCVPEHVIAEAIRKKPRSMLLSTEQLKLCVLEYQGKYILKVCGCDEYLLE
KYPLSQYKYIRSCIMLGRMPNLMLMAKESLYNQIPVDIFTMPSYSRRISTAAPYMNGETS
AKSLWAINSTLRIKILWATYVNVTIRDIDKIYVRTGIYHGVEPLCDNVNTQRVPCSNPRW
NEWLLYDMFIPDLPRAARVCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMAL
NLWPVPHGLEDLLNPIGVSGSNPNKETPCLELEFDCFSSPVKFPDMTAIEDHANKVLERE
LGYNYSHSGLSNRIVRENEVRENDKEQLRAISNRDPLSEITEQEKEFLWSHRLYCRNIPE
VLSKLLLSVKWNCRDDVSQMYCLLKEWPAIRPEQAMELLDFNYPDRIVRSFAVSCLEKYL
TDDKLSQFLIQLVQVMKYEQYLDNHLVRFLLKRALVNQRIGHFFFWHLKSEMHNKTVSQR
FGLLLESYCRACGMYLKHLSKQVEAMEKLINLTDILKQEKKDETQKVQMKFLFEQMKRPD
FMDALQGFTSPLNPAHQLGNLRLEECRIMSSAKRPLWLSWENPDIMSEMLFLNNEIIFKN
GDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRCSHTIMQIQCK
GGLKGALQFNSHTLHQWLKDKNKGETYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMV
KDSGQLFHIDFG
>A0A1S3GSN4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dipodomys ordii|TrEMBL
MEFWTKEENQSVMVDFLLPTGVYLNFPVSRNANLSTIKQVLWHHAQYEPFFHMLSDPEAY
VFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVARECDHVKKLINSQISLLIGKGLHEF
DSLRDPEVNDFRDKMRQFCEEAVAHRQQLGWEAWLRYSFPLQLEPLARSLGAGTPKTPNQ
TMLVNVKFEGNEESFTFQVSSKDKPLALMACALRKKAKMFSQCLVEQPEDYALRVNGRHE
YLYGSYPLCQFQYICSCLHSGRTPHLTMVHSSSILTMRDEQSNPTPQVQKPCTKPPPIPA
KKPSLVSLWSLEKAFCIDLIQGSKVNADERMKLVVQAGLFHGNELLCKTVCSSEVSMCSE
PVWQQRLEFEINVCDLPRMTRLCIMLYAVVEKTKKARSTKKKSKKADCPIAWANLMLFDY
KNQLKTGECCLYMWPSVPGEKGELLNPVGTVCSNPNTKSASTLLICLPEVAPHPVYYPAL
EKILELGHHGERAHATEEELQLREILERQGSGELYEHEKDLVWKLRHKVQEHFPEALARL
LLVTKWNKHEDVAQLHLTTSTPTPQMLYLLRSWPELPVLSALELLDFSFPDCHVGSFAIK
SLRKLTDDELSQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVP
SVALRFGLILEAYCRGCTHHMKMLMKQGEALSKLKALNDFVKVSSQKMTKPQTKELMHLC
MRQDTYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEETGYAGNMGIIF
KNGDDLRQDMLTLQMIQLMDILWKKEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQ
LNNSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCERAYTILRRHGLLFLHLFALMRAAGLPDLSCSKDIQYLKDSLALGKTEEEALKHFRVK
FNEALRESWKTKVNWMAHNVSKDNRQ
>A0A665V7U3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHHLLQEETSYILSEAER
EEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPEVQDF
RRNILNVCKDSVELRDATGPHSRALYVYPPNVESTQELPKHIYSKLDKGQIIVVIWVIVS
PNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQGKYILKVCGCDE
YLLEKYPISHTSVVASCWAGMPNLMLMAKDSLYTQLPTDNFVMPSYSRRISTATSYMNGE
AAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQMCDNVNTQRVPCSNP
RWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVANKM
ALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSSPVKYPDMNAVEDHANWTIS
RELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPLSEITEQEKDFLWRHRHYCMNI
PEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAMELLDCNYPDPMVRHFAVRCLDK
YLTDDKLSQYLIQLVQVLKYEQYLDNPLARHFFFWHLKSEMHNKTVSQRFGLLLEAYCRA
CGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSP
LNPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTL
QIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNS
NTLHQWLKDKNKGEMYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDF
GHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECTKTKEFERFQEMCYKAYLAIRQH
ANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKSEQEAVDYFMKQMNDAHHGGWTTK
MDWIFHTIRQHALN
>A0A674MHH7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
MPPAMTDLLDIWATHAPLAGHDPDQITMDFLLPTGIYIQCDVPRVATIKEIKQLLWKEAH
SFPMFSKLGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRGERLLD
SKIGVLIGKGLHELSAINDQEVKDFRSKMTRISEERMQTIERMTCTEWLQASYSSQLDVP
ADTTTMDGTDRPADLKIIIHFDQSLVRAPVRKWLTTHGPEEDALRGQYVLRVSHCLEFLC
GDHPLIQYKYIRTCMQAKEPPHVTLVHNNTIKTMFERDICAIRAALTPKSCSLPLPLPPK
KRAPTVRSSFVSMHVQVRAGLFHGTELLCKPAVSSESSGRSDHAWKDTTLEFELPVCDLP
RMTRLCFAIYAVMDKVKKQKSTKNTHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTG
DIILHCWSSFPDELEEMLNPIGTIQTNPYTENATALHISFPEYSSHPIIFPLFDKVIIVI
IRPRLMRNLINVSSFGRGGKKFHIELKEIMERDALSQLCENEKDLIWTLRYDCRENFPQS
LPKLLLSVKWSKHEDMAQLQALLQIWPRLCPRDALELLDFNYPDQYVREYAVNCLRDMSN
DELSQYLLQLVQVLRYEPYYDCALTHFLLERAQSSRKIGHFLFWHLRSEIHMPAVSVQFS
LILEAYCRGSIPHIEVLKKQVEALNKLKAVNELIKLGTLKNARSKTKEAMLTKEAMMTCL
RQTGFSETLSDLHSPLNPNILLSGINVEKCRYMDSKMKPLWIVYNNKLLVGDMLGIIFKN
GDDLRQDMLTLQILRLMDRLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLT
SSNMAAAAAFNKDALLNWLKERNSGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRSNGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGQAEKFGSFRQYC
EKAYLILRKNGNFFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSDDEALKQFRQKFD
EALRESWTTKVNWMAHNVAKDNRS
>A0A674PEI6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKHPISQYKIYVRTGIYHGGEQMCDNVNTQRVPCSNPR
WNEWLTYDMYISDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTHTLVANKMA
LNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSSSVKYPDMNAVEDHASRTISR
EVGLNYTLSGQSNRAARDHILTEGDSEQLRQLTNRDPLSEITEQEKDFLWRNRYYCMNIP
EILPKILLAVKWNSRDEVAKMYCLLKEWPSIRPEQAMELLDCNYPDPMVRHFAVRCLDKY
LTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQ
RFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMRFLVDQMKRP
DYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFK
NGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRSSHTIMQIQC
KGGLKGALQFNSNTLHQWLRDKNKGEMYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIM
VKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECVKTKEFERFQE
MCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKTEQEALDYFMKQ
MNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8J6FX15|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eleutherodactylus coqui|TrEMBL
MPPTVSDPMDIWADDIQFSPKVSVDILLPTGIYVQMKVPRDASISQIKQLVWKDAQSYPL
FHLLLEIDSYMFQCVNQTAVHEELEDESRRLCDVRPFLPVLKLVTRSCNPAEKLDSKIGV
LIGKGLHEFDALQDNEVKEFRSKMRKISEDKIQSMLGLTWMEWLKCTFPPELEPSIQDSV
QEKLSGRNLVVAIHFENCQDVFSFQVTPNIIPVKLIELAIRKRLTIHGREDDDVDPEDYV
LQVSGRLEYVFGDFPLIQFQYITNCVMNKTLPRLTLVERCNIKKMFEQEMTAIELAVRRK
PSVPPLPLPPKTRGASMVTKSVCDFNEPYKIMLIKGSKLNTEDTVVVRAGLFHGTELLCI
PIMSSEVPGKNDHLWNETLEFDINVCDLPRMARLCLAIYTVLDKTKNKKSNKTSNTKYQT
IKKAGKMHSPVAWVNTMVFDFKGQLKMGEHVLHGWSSFPDELEEMLNPMGTVQTNPFTEN
ATALHIKFTEYSKVGIYYPPFDKGRGGKKFNIELKEIMERDPLCQLCENEKDLIWTLRYD
CRENFPCSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPRDALELLDFNYPDQYVREYAV
NCLRSMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRAEIHI
PAVSVQFGLLLEAYCRGSVAHMKVLSKQVEALNKLRTLNGLIKLNAIKQSKVKNKETMHA
CLKQNAYREALSDIQSPLNPSVTLSELVIDKCKYMDSKMKPLWIVYNNKGFGGDYTEIMF
KNGDGEPRNICRIIPYGCLATGDRCGMIEVVSAAETIADIQLDCSNLAAAAAFNKDALLN
WIKEYNAGDDLERAIEEFTLSCAGYCVATYVLGIGDRHNDNIMVRKTGQLFHIDFGHILG
NFKSKFKIKRERGPFILTYDFIHVIQQGKPGNTEKFGRFRQCCEDAYLTLRRNGNLIITL
FALMLTAGLPELSSVKDIQYVKDSLALGKTEEEALKQFRQKFDEALKESWSTKVNWMAHT
VRKDYKS
>A0A8C5BG97|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MVDFLLPTGIFLEFPVSRNDTIADIKKLVWRRASSEPLFNALGDPASYVFVCISSAAERL
ELEAEHRRLADVRPFACFLQLVAREGDRAEKLANAQISLLIGKGINEFEAQKNHEVSEFR
ARLRAFCEEKALQQQALPWFQWMECNFPCDLEPLWALNPVPLYGGQTPSPLHSPGPSSFM
LQQDPQEPPLALIRSALKKKATVFRWVRQEAEDYTLRVNGRWDFLYGDHPMCQFKYIFSC
LRDGQNPQLTMVYHSTIRAYQEDQGSAWRQGSKSSTSASKPPPLPLKKVGRRGGLCLSLS
PSLSVCLSAGLFHGSELLCKLVTSSEVAVGSDPVWNQRLEFDINVADLPRMSRLCIALYA
VVEKAKKPRGTKKKSKRDCPIAWVNTMVFDYKDQLKTGEFLLSMWPSIPDDKSELLNPMG
TVEKNTNVDSAAALLIHFPSVRPQPLYYPPHDKVTGGGGSRAPHRSSVDLWCNGLGPLGG
HVRLKEIMDNKNHTEFFEDEKELLWKLRGAVQSLYPESLSKLLVITKWNKREDVAQMVGL
LRAWPELSGLHALELLDYSFPDPSVRAFTVKCLKKLGDRELMQYLIQLVQVLKYESYLDC
DLTSFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGNIHHIRSLTKQNE
ALGKLKALSDIVKSGSQKMSADDLKLCIKQDSYMEALSDLLSPLNPSIILSEICVEKCKY
MDSKMKPLWLMYKNQWVPGDLMGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIP
YGCLSTGNKMGLIEVVKNSDTIANIQRDNSNSAATAAFNKDALLNWLKSKNPEHKLEQAI
EEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPF
ILTYDFVHVIQQGRTNNSEKFERFRDYCERAYKILCRNGTLFVNLFAMMKAAGLPELSSF
KDIQYLKDSLALGKTEEEALKSFKVKFNEALRESWKTKVNWMMHSLAKDKRP
>A0A674GXG8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGV
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGRTPHLTMVHSSAIIAMRDEQTNGITSPPKAA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQNPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L0CZL8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rostratula benghalensis|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKNTKVPEMVLLE
IAGNCTVEQMKAQIWMRAIEMSQTADFYHTFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDDPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIGTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQEAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>H0Z4J4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MPPAVTDSLDIWAVDSQIAADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQETVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKGRGGKKFYVVLKDIMERDPLSQLCENEMDLIWTLR
YDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPREALELLDFNYPDQYVREY
AVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQMLFWHLRSEV
HIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAMKQSKAKGKDAM
HTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKPLWIVYNNKMFGGDLVGI
IFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATGDHSGLIEAVSSSETIAD
IQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRF
RQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSIKDIQYLKDSLALGKSEEEALKQFK
QKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A674GC29|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGV
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGRTPHLTMVHSSAIIAMRDEQTNGITSPPKAA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLVITKWNKHEDVAQLFSFWSLQMISLLQTWPELPVLNALELLDFSFPD
RYVGSFAVNSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFW
HLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKP
QTKEMMHMCMKQETYREALSHLQNPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETG
GGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMH
SDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLG
IGDRHSDNIMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNN
EKFERFRGYCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEE
ALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A674HPB0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MPPAVTDSLDIWAVDSQIAADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQETVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQALLQIWPKLLPREA
LELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALG
NRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLI
KLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKPL
WIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATGD
HSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSCA
GYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSIKDIQYLKD
SLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C2DRD3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVAQS
GKSRSVKKILVNVKFEGSEETFVLQQDPQDLPMLLKRNALRKKSTVFRAAKQEKPEDYTL
QVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQMSRTRA
PSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGMNGEKVVTTKEEHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQ
RYPESLPKLLLITKWNKHEDVAQCIFFLSQMVGLLRKWPELPAIHALELLDYSFPDPHVR
SFTIRCLRNLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRS
EMHVPSVSLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTE
DMKVCIKQDTYMEALSDVVSPLNPSIVLCELCTDKCKFMDSKMKPLWLMYKNKYDHVGII
FKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANI
QRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFR
ECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKV
KFNEALRESWKTKVNWMMHTFAKDNR
>A0A8C2D5R4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLHH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSADLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKIAHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYIPAAVCHLRQRQHQRHRQETCQSLICDRNISRRRTAV
>A0A8C1FSV8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVI
SNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNDLGMNGEKTTKEERDCGHKNYTEFFEDEKELLWKLREEVRQRYPESLP
KLLLITKWNKHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLSDDE
LFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSLRFGLI
LEAYCRGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEA
LSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQDMLTL
QMIQLMDVLWKTEDESQNHIVTAGKGSNMTWSTFSEEQCSVQLFRTNKELMNNYHKTERQ
SWIIQVTTHSIKNQGFPNF
>A0A0F7Z525|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crotalus adamanteus|TrEMBL
MPPAMADILDIWAVDSHIAADSSISVDCLLPTGIYISLDVPRDATICHIKQLLWKQAHSY
PLFHLLLEIDSYMFSCVNQTAVREELEDETRRLCDIRPFLPVLQLITRSCDPGEKLDSKI
GVLIGKGLHEFDALQDPEIKEFRIKMRQISEEKMQSLMGLSLMNWLKHTYPPELGPAIQD
NFQDKLYGGNIVVAVHYENSQDVFSFQVSPNINPIKLNEMAIRKWLTIHGKEDEEVDPCD
YVLQVNGRLEYVFGDHPLIQFQYIHRCVINRALPQLTLIECSTIKTMYEQEMIAIETAVN
RKSNNLPLPLPPKKSRVTQSVWEIGQPFKILLVNGSKLDAEETAKVHIRAGLFHGNELLC
KPIVSSEIAGKNDHVWNEPLEFDINVCDLPRMARLCFVVYAVMDKMKNKKSAKALNPSKY
QTMRKSGKVHYPVAWVNTMVFDFKGQLKTGDLLLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATTLQIRFQEYSKCPIYYPPFDKILEKAAEIARNSDCSGMAGRGGKKFFIELKEIMER
DPLSQLCENEIDLIWTLRFDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPR
EALELLDFNYPDQYVREYAVGCLRQMSDEELAQYLLQLVQVLKYEAFLDCALSRFLLEKA
LANRRIGQMLFWHLRSEMHISAVSLQFGVILEAYCRGSITHMKVLSKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQRAYREALSHLQSPLNPSVLLSELCIEKCKYMDSKMK
PLWIVYSNKAFGGDLVGIIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRLLPYGCLAT
GDYSGLIEVVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNTGEDLDQAIEAFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSDEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A2K6FR52|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Propithecus coquereli|TrEMBL
MCFTFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRTFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSIFENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
ASPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRKSSNLPLPLPPKKTRVISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAISVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYSNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A4X2KWV4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vombatus ursinus|TrEMBL
MDLEDQEPVVLREDNRGRRRRMKPQSAGISSSSMELIPIEFVLPTSHRNTSVSETVILEA
AGSCNVEQMKAQVWMQAMETSMTMEFYHQSSPEQFLLLYQKKGQWYEIYDKYQLIQTLDC
VKYWKALHKNMGQIHVVQRQLPTEETREFQQQLNDLIGYDVTNMSNVHDDELEFTRRRLV
TPRIMEVAIRDPKLYAMHPWVTSKPLPTYLSKKIVNNCILIVIHRSTTSQTIKVSADDTP
GTILQSFFTKMAKKKSLMDIPESQSELDFVLRVCGRDEYIVGETPIKNFQWIRHCLKNGE
EIHLVLDTPPDPGQDEVRKEEWPLVDDCTGVTGYHEQLTINGKNHEKVFTVSLWDCDRRF
RVKIRGIDIPVLPRNTDITVFVEANIQHGQQVLCQRRTTSKPFTEEVLWNVWLEFDIKIK
DLPKGALLNLQIYCGKAPAQSSKAAGSYESSSFETKGKTRLLYYVNLLLIDHRFLLRHGE
YVLHMWKISGKGEDQGSINADKLTSATNPDKDNSMSISILLDNYCHPIALPKHRPTPDPE
GDRVRGEMPNQLRKQLEEIIATDPLNPLTAKDKELLWHFRYESLKHPKAYPKLFSSVKWG
QQEIVAKTYQLLARREAWDRSDLDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHY
LLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEA
YLRGCGMAMLEDFTKQVQVIRMLQKVTIDIKSLSAEKYDVTSQVISQLKQKLENLQNSNL
PKSFRVPYDPGLRAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLR
QDMLILQILRIMGSIWEAESLDLCLQPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNT
GAFKDEVLNHWLKEKCPIEEKFQAAVEKFVYSCAGYCVATFVLGIGDRHNDNIMITETGN
LFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDICVKAYLA
LRQHTNLLIILFSMMLMTGMPQLTSKEDIDYIRDALTVGKNEEEAKKYFLDQIEVCRDKG
WTVQFNWFLHLVLGIKQGEKHSA
>A0A091P2S8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Haliaeetus albicilla|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSVSVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKASNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHIWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHVKFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C9X1N2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MPPGKYGMQEEGDQEIMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNARSEALFSALGD
PDAYVFTCINQTAEREELEEESRRISDVRPFMGVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFEAQKNHEVNEFRAKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPECGSVK
SKNTKKIFINVKFEACDESFMLQQDPQDFPVALMKSALKKKATVFRSVRQEPEDYTLQVN
GRWEFIYGNHPMCQFKVSDRSRLKPQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQA
GLFHGSELLCKVVTTSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPR
GTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNV
DSAAGLLIRFPNIRPHPLYYPPLDKVRILKSDMEKNGDAAIVTKEERMKLKEIMDNKNHT
EFFEDEKDLLWKLRTEVRDHYHESLSKLLLITKWNRREDVWKCLTWRDLPAIHALELLDY
SFPDPVVRSFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWRIGH
FLFWHLRFCASSAAFCLTGEFMFINEALGKMKALSDFVKSGSQKMTADDLKLCIRQESYL
EALSDLLSPLNPSIILTEICADKCRFMDSKMKPIWLMYNPCTQEDMVGIIFKNGDDLRQD
MLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAAT
AAFNKDALLNWLKSKNPEDKLDRAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQL
FHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKIL
CRNGMLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESW
KTKVNWMMHSLAKDNRP
>A0A8C9XEN9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMLLTLECLREATLITVKHELFKEARKYPLYN
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESCAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPCAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMTIIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQHCVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFESQIKMGD
>A0A8C9X1U5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MPPGKYGMQEEGDQEIMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNARSEALFSALGD
PDAYVFTCINQTAEREELEEESRRISDVRPFMGVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFEAQKNHEVNEFRAKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPECGSVK
SKNTKKIFINVKFEACDESFMLQQDPQDFPVALMKSALKKKATVFRSVRQEPEDYTLQVN
GRWEFIYGNHPMCQFKYMFLCLRNSQIPHLTMVHHTTISKYQEEQGRMCSQGYKTRSLSR
PPPLPLKKNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTTSEV
TVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVNT
MVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPL
YYPPLDKVRILKRGKTFYISHFTSLTQLKRMKLKEIMDNKNHTEFFEDEKDLLWKLRTEV
RDHYHESLSKLLLITKWNRREDAVQMMSLLRTWRDLPAIHALELLDYSFPDPVVRSFTIR
CLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLRSEIHVA
SVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDFVKSGSQKMTADDLKLCIRQE
SYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPIWLMYNPCTQEDMVGIIFKNGDDL
RQDMLTLQMIQLMENLWKKEGLDLRDKLDRAIEEFTLSCAGYCVATYVLGIGDRHNDNIM
IRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYC
ERAYKILCRNGMLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFN
EALRESWKTKVNWMMHSLAKDNRP
>M3YCJ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mustela putorius furo|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSVLENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDQPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAIYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSIGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3P8PFU7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astatotilapia calliptera|TrEMBL
MAPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLTTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYSKLDKAVLPMLLPSKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLKMCVQEYQGK
YILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMDFFTMPSYAR
RISTATPYMNGETATKNLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGIYHGGEQLCD
NVNTLRVPCSNPRLWNEWLTYDMYIPEVPRAARLCLSICSVKGRKGAKEEHCPLAWGNIN
LFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHYSSPVKFPD
MSTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDGDNEQLRQVCNRDPLSEITEQEK
DFLWRHRHDCINMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNFPD
PMVREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFF
WHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLKQEKKDEAQ
KVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWENPDM
MSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLI
EVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRSCAGYCVAT
FILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGT
QECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLAL
DKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>B0ESS7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Entamoeba dispar (strain ATCC PRA-260 / SAW760)|TrEMBL
MRLTCYECLAMGNAVGMIEVVLRSETIAAIQKKMYGGNVSAAFQEDPLYKWLKDKNASDD
EFLNAQQNFIYSCAGYCVATYVLGVGDRHNDNILLTPTGHLVHIDFGHILGNVEKFKGFK
RETAPFVLTKEFVYVMGGKNSEGFKLFVNLCCDTFLILRKNYHGLVNLFTMMLSTGLPEL
RRTEDMIYLLNSLVLDMNEVDARAYFEKLINVALEAVMTRVNNAIHIFAHPDVKEDV
>A0A4W3H5S0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPGMQYHQDLWSEDENPDVEVEFLLPTGIYLNFYVPRSSTISYIKKLLWQQAQQQPLFH
TLNEPDAYVFTCINHTAEREELEDERRRLCDVRPFLPVLKLVAREGDRAEKLINSQISLL
IGKGLHEFDCMQDYEVAEFRLKMRQFCEDKESERLRMSWQDWMEYSFPRELEPIQEAPDN
NMIRTLSNRNIVINVKFQYNEESFSFQISPQSHPGTLMQMAVKKKATVFRHKTVEHTEDY
TLQVNGTEEYIYGNYPLGQFKHIWNCMYSSSTPHLTMVHSSTINSLKGEQSNSIAQVPKS
RTYSKPPPLPIKKVIIVLHFHLLHPFSLPLVVQAGLFHGSEMLCKTVSSHEVSVCSEPAW
DQALEFDIHFSDLPRMTRLCFALYGVIDKAKKARSTKKKSKKADCPIAWVNTMVFDYKDQ
LKTGDVWLHMWPSIPDEKGELLNPMGTVQGNPNTDSAAALYVRFRNMGSYPIYYPSFDKE
ATTGKEDRQLKEIMERKSCTEFFEDEKDLVWKLRWESRDHYSDALAKLLSITKWNKHEDV
AQMIYLLQSWPELPALHALELLDYSYPERYVRSFAINCLKNLRYEELFQYLLQLVQVLKY
EPYLDSELTKFLLNRALANKKIGHFLFWHLRSEMHVPAVSLRFGLILEAYCRGNNYHMKS
LMKQCESLKKMKALNDFVKSSSQKTTKPKTKEALHLFMRQEAYMEALSNLHSSLNPSSLL
TDLWYCKFMDSKMKPLWIVYKNEKYDGDPMGVMFKNGDDLRQDMLTIQMIQLMDVLWKRQ
GLDYRMIPYACLSTGDKTGLIEVVSRSETIANIQLNKSNMAATAAFNKDALLNWLKSKNP
GEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKSKFG
INRERVPFILTHDFVHVIQQGKTSNSEKFERFRKYCEHAYMILRKHCPLFINLFALMRAA
GLPELSSSKDIQYLKDSLALGKTEEEALKHFKMKFDEALRESWKTKVNWMAHNVAKDNRS
>A0A2U3WV15|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Odobenus rosmarus divergens|TrEMBL
MCFSFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECFKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVDCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C6UXI8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neogobius melanostomus|TrEMBL
MCLFLFSVSRQLLWKQAQSFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFL
PVLKLITRNCGRAERLLDSKIGVLIGKGLHELDAINDQEVKDFRGKTLRQSEEKMQKVQM
MSCTEWLQASFSQQLEPGPGPDQINGISHFVQDSASLKVPLSCTPPELMDMAVRKWLTTH
GPEKEASRGQYFLRVSHSLEFLCGDDPLSHYKYIRTCVQTKEPPHLTLVHSSIIQEMFDK
EVSAIGAFNVILCCHFLLQHIQTCVWDVSSPFKIVLVNASKVNAEETAKVKYVSSLVIKF
HGFLLCKPAVSSESSGRSEHTWRDSTLEFEISVCDLPRMTRLCIAIYAVMDKVKKQKSTK
NTHINKYQTIRKSGKVSSPGLCFFFSERLNLQPYLFCQLKTGDIILHCWSSFPDELEEML
NPIGTVQTNPYTENATALHISFPEYLPHAIVFPPFDKILEKAAQIARASDCSPMGRGGKK
FHIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQV
LLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYD
CALTHFLLERAQRNRKIGHFLFWHLRSELHMPAVSVQFSLILEAYCRGSIPHIEVLKKQV
EALSKLKSVNELIKFGTMKNARSKAKEAMLTKEAMMTCLRQSGYYETLSDIHSPLNPNIL
LAEVNVERCRYMDSKMKPLWIVYNNKLLDGDTLGIIFKYGDDLRQDMLTLQILRLMDLLW
KEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKE
RNSGDALDHAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKS
KFGIKRERVPFILTHDFIHVIQQGKTGYTEKFASFRQYCEEAYLILRRNGNLFITLFALM
LTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKD
NRS
>A0A8I5Y949|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rattus norvegicus|TrEMBL
MPPGVDCPMEFWTKEESQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLHVSNRPLLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVERPEEYA
LQVNGRHEYLYGSYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
VKPPPIPAKKPSSVSLWSLEQPFCIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDISICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELMNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGRITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQLSQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAI
KSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHV
PSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKASSQKTTKPQTKEMMHM
CMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEKAGGAGSVGII
FKNGDDLRQDMLTLQMIQLMDFLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANI
QLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFR
GYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRV
KFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P7Z8Z2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcaecilia unicolor|TrEMBL
MFRRNTTIDISCVLSAVFLFCSGPCGYDKYSSLIMPPAMTDSFDIWAVDSQITADGPITV
DCLLPTGIYVQLDVRRETTISHIKQLLWKEAQTYPLFHLLMAIDSYMFECVNQTAVHEEL
EDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSKIGVLIGKGLHEFDALEDPEVKEFRSKM
RKISEEKIQSLLGLSWLDWLKRTFPPELEPSIPENFQDKLYGGNLVVAIHFDNCQDVFSF
QVSPNMNPVKVNELAIRKRLTIHGREDENINPSDYVLQVSGKLEYVFGDHPLIQFQYIRN
CVMNRTLPQLTLVECCNIKKMCEQEMNAIEAAIKRKPTNLPLPLPPKTRTMSLMAQSVWN
FCSPFKILLVRGSKVNAEENVKVQARAGLFHGTELLCKTAVSSEIPAGNDYIWNETLEFD
INVCDLPRMARLCFAVYAVMDKMKTKKSTKTTNTKYPTIRKAGKVHYPVAWVNTMVFDFK
GQLKTGDITLHCWSSFPDELEEMLNPMGTVRTNPYPENATALYIKFQEYSKLAIYYPPFD
KILEKAAEIARQSDSMNMSGRGGKKFYIELKEIMERDPLSQLCENEMDLIWTLRYDCREN
FPQSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPREALELLDFNYPDQYVREYAVNCLK
QMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVQIPQIS
VQFGVILEAYCRGSVAHMKVLTKQVAALNKLRTLNNLIKLNAVKLSRAKGKETMQTCLKQ
STYREALSDFQSPLNPSVILSEMNVEKCKYMDSKMKPLWIVYSNKVFGGDPVGIIFKNGD
DLRQDMLTLQLLRLMDMLWKESGLDLRIVPYGCLATGDRSGLIEVVSAAETIADIQLNSS
NVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTYSCAGYCVATYVLGIGDRHNDNIMVR
KTGQLFHIDFGHILGNFKSKFKIKRERGPFILTYDFIHVIQQGKTGNTEKFGRFRQCCED
AYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTEDEALKQFRQKFDEA
LRESWTTKVNWMAHTMRKDYRS
>A0A093FB92|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tyto alba|TrEMBL
SRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKVL
GTGPLHNPTKNIFVNVKFQSGGESFTFQISPEEFPITLMSYAIKKQATVFRHETVENPED
YTLQVNGKWEYLYGNYPLYQFQYICSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPK
MSAKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQGFSGLSKSSGLRLSAVYALSCDCHEQKLQLKEILERRSHTELYEHEKD
LVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPD
RYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFW
HLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKAAKP
QTKELMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETG
GGGVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMH
SDTIANIQLKKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFFAGYCVATYVLGIGD
RHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKF
ERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALK
HFRLKFNEALRESWKTKVNWLAHNVSKDNR
>A0A091KX58|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chlamydotis macqueenii|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQESV
IPESFQDKLYNGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKPRTTTSVWDLSNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKTEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3B1K528|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDVNGPHSRALYVYPPNVESSPELPKH
IFGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMD
NFTMPSYSRRISTATPYMNGEVSSKALWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHIITEADIDQLRQLANRDPL
SEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGETYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A6J2Q2T9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cottoperca gobio|TrEMBL
MPPGKYGMQEEWEKDGDQEIVMDFLLPTGIFLKFPVSPNDTIKTLKKMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEESRRISDIRPFMCVLRLVAREGDRVKKLTNTQISWL
IGKGLHEFEAQKNHEVNEFRTKMRAFCEEKAQERQMLPWQQWMEYSFPCDLEPCCTPPEF
GKVKSKNTKKAFINVKFEACDESFMLQQDPQDLPMTLIRSALKKKAHVFRSVRQEPEDFT
LQVNGKWEFIYGKHPICQFKYIFLCLRNGQNPHLTMVHHSTIQKFQNAQGLMCSQIYRNR
SLSRPPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSEFLCKVV
TTSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKHKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDMLIPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPPLDKVGDMEKNGDAAIATKEEFMKLKEIMDDKNHTEIFEDEKELLWKLRTDV
RDHYHESLSKLLLVTKWNRHEDVVQMVGLLSNWRDLPAINALELLDYSFPDPAVRSFTIR
CLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLRSEIHVA
SVSLRFGLILEAYCRGNIHHIKILTKQNEALGKMKALSDFVKSGSQKMTADALKLCIRQE
SYLEALSDLLSPLNPSIILAEICPDKCRYMDSKMKPIWLMYNPRVQEDMVGIIFKNGDDL
RQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNS
AATAAFNKDALLNWLKSKNPEDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRET
GQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAY
KILCRNGTLFVNLFAMMKAAGLPELTSCKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKVNWMMHSLAKDNRP
>A0A8D2KFR4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Urocitellus parryii|TrEMBL
MCFSFIMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRIFSEEKIQSLVGLSWIDWLKQTYPPEH
EPSTLENLEDKLYGGKLIVAVHFENCQDVFSFQVSPEMNPIKINELAIQKRLTIHGKEDE
ASPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECSKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNELLEFDINICDLPRMARLCLAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVASRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LSPRDALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A5K1UB41|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A1A7YDR8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Iconisemion striatum|TrEMBL
MPPAMTDLLDIWAAHSPLAGHALDKITMDFLLPTGIYIQMDVPRDATIQHIKLLLWKQAQ
NFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRFTEEKMQQAQVMTCTEWLQACCSPQLEPT
AATILTDGVIDRPADLKVIIHFDQSQDSTSLKVPMSCTPSELMEMAVKKWLTTHAPEDEA
YSRQYVLRVSQCLEFLCGEHPLIQYKYIRNCLQAKESPHLTLVHTSTVNIMFEKEMSAIG
AVVSRKSSNPPLPLPPKRRPPTQVQTCVWNVSKPFKIVLLKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSDSSGRSDHIWKNSTLDFEISVSDLPRMTRLCFAIYAVMDKVKKQKST
KNAHSSKYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDVILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIQFPEYSPHPVIFPPFDKILEKAAQLVGVIEQPISRGGKKFYIEL
KEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQVLLQIW
PKLSPRDALELLDFNYPDQYVREYAVRCLRDMSDEELLQYLLQLVQVLRYEPYYDCHLTH
FLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSEALSDLTSPLNPSIQLSDIN
VEKCRYMDSKMKPLWIVYNNKLMSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRIVPYDCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQEGKTGNTEKFGSFRKYCEEAYLILRRNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A6P5KAG0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phascolarctos cinereus|TrEMBL
MCFSFIMPPAMADILDFWGVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISNIKQMLW
KQAHNYPMFNLLMEIEAYMFACVNQTAVYEELEDETRRLCDIRPFLSVLKVVTRNCDPGE
KLDSKIGVLIGKGLHEFDALEDPEVNEFRSKMRQFSEEKIQSLVGLSWMDWLKHTYPPEQ
EPSIPENLEDKLYGGNLVVAVHFENCQDVFSFQVSPNMNPIKLNELAIRKRLTIRGKEDE
VDPYDYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPKLTLVECCNIKKMCEQEMIAI
EAAINRNSSNLPLPLPPKKTRLISNVWENTQPFQIILVKGTKLNTEETVKVHVRAGLFHG
TELLCKPVVSSEISGRNDRVWSEPLEFDINICDLPRMARLCFAVYAVDKVKTKKSTKTIN
PSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKAGDIILHSWSSFPDELEEMLNPMGTVQT
NPYIENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSGNVSSRGGKKFHAVLKEI
MERDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWPKL
PPREALELLDFNYPDQYVREYAVSCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFML
DRALANRRIGQFLFWHLRSEVHIPAFSVQFGVILEAYCRGSVGYMKVLSKQVEALNKLKT
LNSLIKLNAVKLNKAKGREAMHTCLKQNAYREALSDLPSPLNPCVILSELYVEKCKYMDS
KMKPLRIVYNNKVFGGDPVGIIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGC
LATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDQAIEEF
TLSCAGYCVASYVLGIGDRHSDNIMVRKTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFNRFRKCCEEAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTMRKDYRS
>A0A6P5J7B6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phascolarctos cinereus|TrEMBL
MPPGVDCPMEFWSKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVARQGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWEAWMHYNFPLQLEPCARGLGT
GTLRVPNRTLLVNVKFEGNEESFTFQVSPNDFPLALMACALKKRATVFRQSAMERPEDYT
LKVNGKFEYLYGGYPLHQFQYICNCLHKGLTPHLTMVHSSSILAMRDEQSNPTAQAPKLR
TKPPPIPVKKPSSVSLWSLEQPFCIELVQGSKVNADERMKLVVLAGLFHGNEMLCKTVSS
SEVTVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWSSVPDEKGELLNPMGTVRSNPNTESAAALVICIPEVAP
HPVYYPTMEKILELGKNGEHGRFTEDELQQLREILERKVAAELYEHEKDLVWKMRHEIQE
QFPEALARLLLVTKWNKHEDVAQMLFLLGSWPELPVLSALELLDFSFPDRHVGSFAIQSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSNHHMKALMKQGEALNKMKALNDFVKVSSQKTTKPQTKELMHVCMR
QETYLEALSNVQSPLNPSTLLSEVCVEQCTFMDSKMKPLWIVYSNEEAGGGGDSHVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVSHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRS
YCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6J0GWK1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lepidothrix coronata|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMAVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A1S3T6K9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo salar|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHEVFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKCPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGESSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMTTVEGHANWTISRELGFNYCQSGQSNRVARDHALTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNIRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCMS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDLAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8B7F994|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcebus murinus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPLFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRTFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSIFENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
ASPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRKSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDLILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAISIQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A1U8D8B0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alligator sinensis|TrEMBL
MPPTVTDILDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLLEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSRI
GVLIGKGLHEFDALPDPEVKEFRTKMRRISEEKNHSLVSLSWMDWLKHTYPPEQEPSIPE
NFQDKLYGGNLVVAIHFDNCQDVFSFQVSPNINPIKLNELAIRKRLTIRGREDEEINPSD
YVLQVSGRLEYVFGDQPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCDQEMIAIEAAIN
RKSSNLPLPLPPKKTRTATQLTQSVWDISNPFKIILLNGNKLNTEETTKVSVRAGLFHGT
ELLCKPIVSTEVSGRSDHVWNETLEFEVNVCDLPRMARLCFAVYAVMDKMKTKKSTKTMN
TAKYQTIRKAGKVHYPVAWVNTMIFDYKGQLKTGDLILHSWSSFPDELEEMLNPMGTVQT
NPYAENATALHIKFQEYSKLPIYYPPFDKILEKAAEIAKSSDSAMAGRGGKKFYVVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWTKL
PPREALELLDFNYPDQYVREYAVGCLKLMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQVLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLSKQVEALNKMKT
LNGLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHIERCKYMDS
KMKPLWIVYNNKMFGGDFVGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFDRFRQYCEEAYLILRRHGNLFITLFALMLTAGLPELTSIKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A1U7RV73|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alligator sinensis|TrEMBL
MELGNHEQPVVMREENKRRRRRMKPYCTANNLSSMELIPIEFVLPTSPKHTKTPEIVTLE
IAGNCTVEQMKAQIWMHAIEMSQTSDFCHKYTPDQFILQYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGRIYVVQKQKPSVEVQEFQKQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYSMHPWITSKPLPEYLFKKITNNNIFINIHRGTTSQKIKISIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPVKDFHCIRQCLKNG
EEIHLVLDTPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDITVFVEANIQHGQQLLSQRRTASKPFTEEVLWNTWLEFDIKI
KDLPKGALLNLQVYCGKTQSLSTKANLQSHDSPSSDSKCKTQLLYYVNILLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAVSIVLDKYCHPIALPKHRITSD
TQGDGARTEMPNQLRKQLEEIIATDPLNPLTAEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQDLVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLECLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLKGCGKAMLCDFMKQVQVIELLHTVTMEIKSVSAEKYDVTSQVITQLKQKLEKLQNN
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITES
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSQHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3B3BLJ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias melastigma|TrEMBL
MPPAMTDLVDIWGAHSPLDGQAPVHVTMDFLLPTGIYIQMEVPREATIQHIKLLLWKQAK
SYPLSSFLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVFRLVTRNCGRAERLLD
SKIGVIIGKGLHELDGINDQEVKDFRSKMQRLSEERMQRVQMMSFSEWLQACFSPQLEPA
AGTAITDGANDWPADLKVIIHFDQSQDSTSLKVLSSCSPFVLIEIALRKWQTTHAPEEET
KKDQYILRVSQCLEFLYGDHPLIQYKYIRSCLQTKESPHLTLVHINTVKAMFDKESSAIG
AVVSRKSSNPPLPLPPKKRAPTQVQTCVWDVSSPFKVVLVKGSTVNADENAKVQVRAGLF
HGTELLCKPAVSNESSGRSNHSLENNTLEFEISVCDLPRMTRLCFAIYAIMEKVKKKSYK
NPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDMILHCWSSFPDELEEMLNPIGT
VRTNPYPENATALHIHFPEYSSHPIIFPPFDKILEKAAEIAGSSDSTPIGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVSCLRDMSDEELLQYLLQLVQVLRYEPYYDCALTH
FLLERAQRNRKIGHFLFWHLRSEIHMPAVSIQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNTRSKTKEAMLTKEAMITCLKQSGYSEALSDLHSPLNPNVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLMSSDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRVVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLVLRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKSDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8B8XBE0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balaenoptera musculus|TrEMBL
MCFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDCVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRALPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKAI
NPSKYQTIRKSGKVDYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVDALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYIEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDHSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7E6DPR9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phyllostomus discolor|TrEMBL
MPPGVDCPMEFWTSEENQNVAVDFLLPTGVYLNFSVSRNANLSTIKKALWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYCFPLQLEPSARTWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDMPLALMTCALRKKATVFRQPLVEQPEDYT
LQYICSCLHRGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRTKPPPIPMKKPSSVSLWS
LEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSVCSEPVWKQRLEFD
INVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLTLFDYKDQLKTGEYC
LYMWPSVPDEKGELLNPTGTVCSNPNTESAAALIICLPEVAPYPVYYPALDKILELGRHG
EHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQERFPEALARLLLVTKWNKH
EDVAQMLCLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQV
LKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSIHH
MRVLMKQGEALSKLKALNDFVKVSSQKTPKPQAKELLHVCMRQETYLEALSHLQSPLDPS
ILLAEVCVEQCTFMDSKMKPLWVMYCNEEAGSNGSVGIMFKNGDDLRQDMLTLQMIQLMD
VLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNW
LKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGN
FKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLF
ALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNV
SKDNRQ
>A0A7J8DCZ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Molossus molossus|TrEMBL
MCFNFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISSIKKMLW
TQIHNYPMFNLLMEIDSYRFACVNQTAVYEELEDETRRLCDVRPFLPVLKVVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWIDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQISGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAISRNSSNLPLPLPPKKRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGT
ELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTIN
ASKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQT
NPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEI
LDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKL
PPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQFLFWHLRSEVHIPAISIQFGVILEAYCRGSVGHMKVLSKQVEALNKLKT
LNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYIEKCKYMDS
KMKPLWLVYNNQVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGC
LATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEF
TLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A671P9E0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEMREGGGAHTQALYVYPPNVESSAELPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKITHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDEYLLEKHPLSQYKYIRSCITLGRLPHLMLVSKDSLYSQLPSS
GFMAPSYSRRTPQPSPCPGGGDPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDELQIEEHANWSISRELGYSYCLGLSSRLVCDSSISQADAEQLRTLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQIYCLLKDWPLMQPESAL
ELLDCNFPDPMVREFALRCLIQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIRDKNKGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFESIFCTFELFPAAF
>A0A671SHF1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPSAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYTMPLEAGSLE
SLIDKHEDDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGFRSDYVLRVSGKLEFLF
EDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIGSVIARKTSNPPLLLPPK
KRLPTASTLFPALQLIQGVLSFAYLAVRAGLFHGTELLCKTAVSSESSSRSEHVWNKTLE
FDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIPWVNTMVFDYRGQLKTGN
VLRKCLFFLCVADELEEMSLLIKDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVK
WSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVYCLRDMSDDELLQYLLQ
LVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMFMPAVSVHFALILEAYCRG
CIPHIEVLKKQVEALSKLKAVNELIKFGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLH
SPLNPNILLAGINVERCKYMDSKMKPLWIVYNNKLLEGETVGIIFKNGDDLRQDMLTLQI
LRLMDLLWKEANLDLRIVPYGCLATGDHAGLIEVVSSADTIANIQKTSSNMAAAAAFNKD
ALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFG
HILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNL
FITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNW
MAHIVAHPS
>A0A8C0AVF1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Buteo japonicus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERGFF
>A0A2I4KAQ6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tachysurus fulvidraco|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLVTIKHELFKEARKFPLHH
LLQEEASYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDSNGPHSRALYVYPPNVESSPELPKH
IFGKLDKGQVIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMD
TFTMPSYSRRISTATPYMNGEASSKSLWTINSNLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLMYDMNIHDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SCPVKFPDKATIEDHAIKMLSRETGYNYFQSGQSNRQARDHHIMESDLEQLRQIANRDPL
SEITEQEKDFLWRHRQYCKTIPEILPKILLAVKWNARDEVSQMYCLLKGWPQIKPEQAME
LLDCNYPDPMIREFAVQCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLGRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDLAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKEDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A663EN11|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aquila chrysaetos chrysaetos|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLPSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIESLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
RLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A401SG37|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chiloscyllium punctatum|TrEMBL
MTDPLDIWAVDSQIPSDNSITADFLLPTGMYIQLDVPREATIEHIKSLLWTQAQTYPLYS
VLGEQDSYMFQCVNQSAVHEELEDESRRLCDVRPFLPVLKLVARNCNRSEKLLDSKIGVL
IGKGLHEFDALTDPEVKEFRSKMRKINEENMLKRQGLSWMDWLQHNFPPEVESASVNNTE
DKLHKDNFLVAIRFESCQDIFNFQVSPNLNPHQLNELAIRKQLTNHGKENEEFNPRDFVL
RISGKQEYLFGEQPLIQFRYIRNCVSKGLHPQLTLVDCSTIKEMCDREMSAIGMALHRKS
SNLPLPLPPKRRTISQMAGNVWDINSPFKIVLARGIKINADEALRVQVRAGIFHGTELLC
KPVVSNEISGKNDLVWNETLDFEINVCDLPRMSRLCFAVYGVMDKVKKQKSTKNVNKYQT
IRKAGKVHYPIAWVNTMIFDFRGQLKSGDLSLHCWSSFPDELEEMLNPMGTTQTNPYTEN
ATELHIQFHEYSKVAIFYPAFDKILEKAAEIARSNDTLSTSGRGWKKLHIELREIMERDP
LSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSVKWNKHEDVAQLQALLQIWTKIAPREA
LELLDFNYPDQYVREYAVGCLKEMSDEELSQYLLQLVQVLKYEPYFDCALSRFLLERAQA
NRRIGHFLFWHLRSEMHLPATSLQFGLILESYCRGSITHIKDLSKQMEALSKMKAINSLV
KISSLKVAKNKLKDVIHTCLKQPVYQEALSNIQSPLNPSVILSELNIDKCRYMDSKMKPL
WILYNNKMLGGEPVGIIFKNGDDLRQDMLALQILHLMDMLWKEAGLDLRIVPYGCLATGD
KSGVIQVVSAAETIANIQLTNSNVAATAAFNKDALLNWLKEKNSADALERAIEEFTLSCA
GYCVATYVLGIGDRHSDNIMVRESGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFSRFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELSSIKDIQYLKD
SLALGKSDDEALKHFRQKFDEALRESWTTKVNWMAHIVAKDKWS
>A0A8C7MLA3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MEQQVSDEEEPQPVVLRAEIRRRRRKMKAFTSTFSVAVDQIAVEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCVRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELSDRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVYTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNAWLEFN
IRIRDLPKGARLSLQVSCGKAQTQISKGGSGSHDGSKTKSRLLYYVNLLLVDHRSLLRQG
EFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYPVALPKSRDGKAA
GGEGREAEGGKRGQREMPNHLRKQFEVIVETDPLHPLSQEDKELLWHFREECMRHPRAYP
KLLGSVLWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLET
LGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQ
QRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQVVFQLRQK
LENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTTLSSDTIGV
IFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTIAN
IQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLGVGDRHND
NIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFQKFQ
DVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEEAQRHLLD
QIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A8C7CJG3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MEQQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPTEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKGAALWATLCCLPAPSLFCIGHILLVIHRNKAS
QTIKVSIDDTPVQALQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDF
HWVRQCLKNGEEIHLVLESALNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVF
TISLWDCHRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLW
NTWLEFNIRIRDLPKGARLSLQVSCGKTQISKGTSSYQDNGGSPTKSRLLYYVNLLLVDH
RSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYPVALPK
SREGKEAGGEGREAEGGERGQREMPNHLRKQFEAIVETDPLHPLSQEDKELLWHFREECM
RHPRAYPKLLGSVRWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSM
AVRKLETLGNDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEI
AQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQV
VFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTTL
SSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVK
DATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLG
VGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSS
PHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEE
AQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A401SUT9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chiloscyllium punctatum|TrEMBL
MPPGIHYNQDFWTEDESPDVEVEFLLPTGIYLNFFVPRSSTIKYIKKLLWQQAQHQPLFH
TLNKPDAYVFTCINHTAEQEELEDEHRRLCDVRPFLPILKLVAREGDREEKLINSQISLL
IGKGLHEFDSLHDPEVNEFRGSMRQFCEERAEERQRFSWQHWMEYSFPRDLEPIPEVPDN
SITRKHSNRNIVINVKFQYTEESFSFQISSQAPPALLMKLAVKKKATVFRHKVVDDAEDY
TLQVNGTEDYIYGNYPLSRFKYICNCMSSNLTPHLTMVHYSTIKSFQDEQFSSLGQITKA
RPHSKPPPLPVKKQFGTSLWNLEKPFMISLISGSKVNADEGMKDCPIAWVNTMVFDYKDQ
LKTGETWLFTWPSVPDDKGELLNPMGTVQSNPNTDSSAALHINFHSAVSHPIYYPSLEKQ
QQLKEIMERKACTEFFEDEKDLVWKLRYEVREHFPEALAKLLSITKWNKHEDVAQMIYLL
QSWKELPALNALELLDYSFPSRYVRLLAINCLKKLSEEELLQYLLQLVQVLKYEPYLDSE
LTKFLLDRALSNKKIGHFLFWHLRSEMHFPAVSLRFGLILEAYCRGTSYHMKSLLKQCEA
LKKMKALNDFVKSSSQKTTKPKTKEAMHLFMRQDTYKEALSNLYSPLNPSILLTELWVEK
CKFMDSKMKPLWIVHKNQRYDGNPMGILFKNGDDLRQDMLTIQMIQLMDVLWKKQGLDYR
MIPYACLSTGDKTGVIEVVSHAETIANIQLTKSNMAATAAFNKDALLNWLKSKNPGESFL
ILKNADSYRPQLFHIDFGHFLGNFKSKFGINRERVPFILTHDFVHVIQQGKTSNSEKFER
FRKCCEQAYMILRRHCPLFINLFALMQAAGLPELSCSKDIQYLKDSLALGKTEDEALKHF
KMKFDEALRESWKTKVNWMAHNVAKDNRS
>H0X8C9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Otolemur garnettii|TrEMBL
MELENYEQPVVLREDNARRRRRMKPRSAAASLSSMELIPIEFVLPTSQRHSKSPETTLLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLSPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHLVQRRAPSEETQAFQRQLTALMGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLCKKIVNNCVFIIIHRSTTSQTVKVSADDT
PGTILQSFFTKMAKKKSLMDISESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKTPALSGKVSADTSSSESRGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPSPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRALAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRALRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSVEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGFNKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVKAYLAL
RHHTNLLINLFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7L4LXC6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Glareola pratincola|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRTAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6G1QRT2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Channa argus|TrEMBL
MLDKAMDRQRIQVSDEEPVVIQEEIRRRRRKKAFTSSSSTSMDQITVEFLLPTVTWGGNN
QDTLQLEVAGNWTVEQVKAQVWLKAVTSNLCPDFYQRACPDHCILLYQKKGNVYEIYDKH
QVFQTLDCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDEL
EFTRRKLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVSNGHILVVIHMSTASQTI
KVSIDDTPAQVLASFFTKTANKRVLLGIPDNMCEADYVLRVCGREEYLYGEKPLQNFNWI
RQCLKNGEEIHLVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTIS
MWDCNRKFRVKVLGIDIPILPKIPELTVFIEATIFHGQQLLAQERTTSKTFNEEVLWNCW
LEFNIKIKDLPKGTRLNLQVVCGKQAQTPNSKGSSYPDNTAGGGSHDGKTKSRLLYYVNL
LLIDHRSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKESSMAIAILLDKYCY
PVVLPKSRDLGRDAGAVGEESEGGERGQREMPNHLKKQFEAIVATDPLHPLSPEDKELLW
HFRHECMRDPRAYPKLLGSVKWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYS
DAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLF
WFLRSEIAQSMHYQQRYAVLLEAYLRGCGEAMLQDFRKQVEMTEALQKVTREIKAVSADK
YDVTAQVVFQLRQKLETLQMSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFK
RADPTTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRI
GMIEIVKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAIERFLYSCGGYC
VATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMG
TSGKKSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALT
VGRSEDEAQHHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A6G1PSX1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Channa argus|TrEMBL
MNPKLVAPVSKNFIDMCTLQDITAKSYCSMVLKWLKVKQDKWSLWLRWCVVPLAMPPAMT
DLLDMWAAHPALAGQTPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQMFPLFP
ALGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRAERLLDSKIGVL
IGKGLHELDAINDQEVKDFRSKMLRISEEQMQRVQMMTCTEWLQACFSPQLEPAAGTAIT
DGAGDRPADLKVIIHFDQSQDSASLKVPSSCTPTELMEFAVRKWLTTHGPEEEGWRGQYV
LRVSQCLEFLCGENPLFQYKYIRICMQAKESPHLTLVHTSTIKAMFDKEISTISAVVSRK
SSNPPLPLPPKRRVPTQVQTCVWDVSRPFKIVLVNASKVNAEEAAKVQVRAGLFHGAELL
CKPAVSSESSGRSDHTWKESTLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKSTRNAHIN
KYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATALHIYFPEYLPHPIVFPPFDKILEKAAEIAGASDCAPMGRGGKKFHIELKEIME
RDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPRLSP
RDALELLDFNYPDQYVREYAVRCLRDMRTISIPASTFFTSDEELLQYLLQLVQVLRYEPY
YDCALTHFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRCNIPHIEVLKK
QVEALSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPN
VLLSGINVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDL
LWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWL
KERNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNF
KSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFA
LMLTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVA
KDNRS
>A0A8D2B2A2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sciurus vulgaris|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8D2DSH5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sciurus vulgaris|TrEMBL
MELENYEQRVILREDNLRRRRRMKPRSEAASLSSMELIPIEFVMPTSQRDSKIPETALLH
VAGHGNVEQMKAQVWLRAMETSVAADFYHRLGPDHFILLYQKKGQWYEIYDKYQVVQTLD
CLRYWKMLNKSPGQIHVVPRHAPSEETLAFQQQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVASRDARLYAMHPWVTSKPLPEYLSKKIFNNCIFIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIFCGKAPALSGKASAETPSSESKGKVQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQESFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPSPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLQDFAQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLETLQNSNLP
KSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGRNEEEAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8D3B7D0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPGKYGMQEEWEKEGVQEIMMDFLLPTGILLKFPVSRNDTIKSIKKMVWKNARSEALFC
GLGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRAEKLINTQISLL
IGKGLHEFEAQKNHEVNEFRTKMCIFCEEKAQERQMLPWQQWMEYNFPCDLEPCCTPPHS
GSLKSKNTKKFFINVKFEACDESFMLQQDPQDHPVALMRSALKKKANVFRSVRQEPEDYT
LQVNGRWEYIYGKHPMCQFKYIFSCLRNGQNPHLTMVHHSTISKFQEEQGQMCSQEYKSR
SLSRPPPLPLKKLNTSSLWSITEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFANI
RPHPLYYPPLDKVLVPKRLCWYMKLKEIMDNKNYTEFFEDEKELLWHLRTEVRDRYPENL
SKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAIRSFTIRCLRKLSDD
ELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVTLRFGL
ILEAYCRGNIHHIKLLTKQNEALSKMKTLSDFVKSGSQKLTAEDLKLCIRQESYLEALSD
LLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNNWAPEDMVGIIFKKGDDLRQDMLTL
QMIQLMETLWKREGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQL
FHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKIL
CRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESW
KTKVNWMMHSLAKDNRP
>A0A8D2ZCV3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQIPVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TLPFFAALGDMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVMKLVMRNCGRAERLLD
SKIGVLIGKGLHELDAMNDQEVKDFRSKTFRISEERMQGVQMMTCTEWLQSCFSPQLEPD
VADGAADWSADLKVIIHFDQSQDSASLKVPSSCTTTELMELAVRKWLTTHGPEEEAWRSQ
YVLRLSQCLEFLCGNHPLIQYKYIRTCVQAKESPHLTLVHNSTVKALFDKELSTIGAVVS
RKSSNPPLPLPPKRRVPTVSPASRMLLFSVQTCVWDMSSPFKIVLVNASKVNAEETVQVR
AGLFHGTEVLCKTAVSSESSGRSDHTWKESTLEFDIPVSDLPRMTRLCFAIYAIMDKVKK
QKSTKNTHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDINLHCWSSFPDELEEML
NPIGTIQTNPYTENATALYIHFPEYSSHPVIFPPFDKGRGGKKFHIELKEIMERDPLSQL
CENEKDLIWTLRWDCLVNFPQSLPKLLLSVKWSKHEDMAQLQALLQMWPKLSPRDALELL
DFNYPDQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGNRKI
GHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGP
TKNARSKTKDAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSGINVERCRYMDSKMK
PLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLAT
GDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNTGDALERAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDF
IHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A444TZB1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acipenser ruthenus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQDETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVDLRDVNGPHSRALYVYPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKESLYTQLPID
NFTMPSYARRISTATPYMNGETSAKSLWTINDTLKIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLKYDMYIPDIPRAARLGLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMSTIEDHANWTISRELGFNYCPTGLSNRLARDNELTESDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHILVNIPEILPKILLAVKWNSRDEASQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDLAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A673HSC7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRVSEEKMQRMQLMSCGEWLRSCYSTQLGTGSLE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDY
VLRVSGRFEFLFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLAR
KTSNPPLPLPPKKRPPTVSTLSVFPAHQLIKGVLSFVHLAAPNSNAKVRAGLFHGTELLC
KTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKY
QTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYT
ENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMERD
PLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLKVQA
VREHIFTWYFNMLMQKLEFMIACVVHYRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKK
QVEALNKLKAVSELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLQSPLNPNILLA
GVHVERCKYMDSKMKPLWIVYNNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKE
ANLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKN
SGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKF
GIKRERVPFILTHDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLT
AGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A673MYB2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
VGDDEPPVVRREENKRRRRKMKAFTSTSAVLTDQIAVEFVLPTTNKNSKNPDTLHLDVTG
NWTIEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTLDCIR
YWKALRKEVGKIHLVVRQQPTEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRKLLSP
RKIELSDRDPKLYSMDPWITTKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDDTPVQ
VLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKNGEEI
HLVLERPPDPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRKFRV
KILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIKIKDL
PKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVDHRSLLRQGEFILHMWKMPE
KSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERGQREM
PNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEAVAIT
HCLLERSTIWDRSSLDVGLALQLLDCHFSDENVRTMAVRKLETLEDDDVLRYLLQLVQAV
KFEPYHDSALARFLLKRALGSMRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGEA
MLQDFRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDSFKVPY
DPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDMLILQI
LLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDEIL
SQWLCEKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDFGH
ILGNYKSFLGISKERVPFVLTPDFLYVMCTTDKKSSPNFLQFQAYLALRHHTNLLIILFS
MMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQFNWFLHLVL
GIKQGVEKRSA
>A0A673HNG1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
SISLLWKEAQTYPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITR
NCGRAERILDSKIGVLIGKGLHELDALQDQQVKDFRSKMKRVSEEKMQRMQLMSCGEWLR
SCYSTQLGTGSLENLIDKHEGDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSD
YVLRVSGRFEFLFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLA
RKTSNPPLPLPPKKRPPTVSTLSVFPAHQLIKGVLSFVRAGLFHGTELLCKTAVSSESSS
RSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIPWVNTMV
FDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVF
PAFDKVCIYSQYEGRYGERLQQLKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPK
LLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVICLRDMSDDEL
LQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMYMPAVSVHFALIL
EAYCRGCIPHIEVLKKQVEALNKLKAVSELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIE
TLSDLQSPLNPNILLAGVHVERCKYMDSKMKPLWIVYNNKLLGGDTVGIIFKNGDDLRQD
MLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQKTSSNMAAA
AAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQL
FHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGNFRQYCEEAYLIL
RKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESW
TTKVNWMAHIVAHPS
>A0A7K4TTB2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinosuthora webbiana|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEILLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRHLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRT
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A315W5Y0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gambusia affinis|TrEMBL
MPPGKYGTLEEWEQDGDQEIFMDFLLPTGIFLNFPVSRNDTIRNIKKMVWKNASREALFS
ALGDPDLYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNAQISLL
IGKGLHEFEAQKNHEVDEFRTKMRTFCEEKSLERQNLPWQRWMEYSFPCELEPCSSPATG
GSSKSKHSKKLFVNVKFESSDESFMLQQDAQDLPVALMKSALKKKATVFRSVRQEPQDYT
LQVNGRWEFIYGQHPLGQFKYIFSCLRNGQNPQLTMVHHCTISKYQEDQGRVCSQMYKTR
SLSRPPPLPLKKLVVQAGLFHGSELLCKMMTSAEVTVCSEPSWDQRLEFDINVSDLPRMS
RLCFALYAVIEKTKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSMWPSVPDD
KNDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPLDKTIEPEMNGNTVFPSKDEY
LKLKEIMDNKNYTECFEDEKELLWKLRAEVRDYFPECLSKLLLITKWNKREDVAQMVGLL
KSWPELPAIHALELLDYSFPDPAVRCFTIRCLKKLSDDELLQYLIQLVQVLKYESYLDCD
LTTFLLERALSNRRIGHFLFWHLKSEIHVASVSLRFGLILEAYCRGNIHHIKLLSRQNEA
LGKMKALSDIVKTGSQKMTVDDLKLCIRQESYLEALSDLLSPLNPSVILFEIWLAADKCR
FMDSKMKPLWLMYKNPLEQADMVGIMFKNGDDLRQDMLTLQTIRLMENLWKKEGLDLRMI
PYGCLSTGNKTGLIEIVKSSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPGDKLDQA
IEDFTLSCAGYCVATYVLGIADRHNDNIMIKETGQLFHIDFGHILGNFKRKLGINRERVP
FILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELSS
SKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLTKDNRP
>A0A7K4UCM4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinosuthora webbiana|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWQQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAARRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVRFQSGGESFTFQISPWEFPLTLMTYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKPA
CKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVAVCSEPVWRQRLDFDIGICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K9MP44|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oceanodroma tethys|TrEMBL
MELGDYEQPVIMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGSCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRATTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMGSIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C9AL15|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Prolemur simus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSCNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARGWGA
GTLRLPNRAFLVNVKFEGSEESFTFQVSTKDAPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGRHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQGQKPR
TKPPPIPVKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVGPRAS
QEGCGPRRARAAPGWRPHRGPGGPLPPRLSQSGHLPCLGDSRPTRNIWPGPLILELGRHS
ECGRVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKH
EDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQV
LKYESYLDCELTRFLLDRALANRRIGHFLFWHLRYSEMHVPSVALRFGLILEAYCRGSTH
HMKVLMKQGEALSKLKALNDFVKASSQKTTKPQTKEMMHVCMRQEAYLEALSHLQSPLDP
STLLAEVCVEQCTFMDSKMKPLWIMYSNEQAGGNGCVGIIFKNGDDLRQDMLTLQMIQLM
DVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLN
WLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLG
NFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHL
FALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHN
VSKDNRQ
>A0A4W6CSS5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLQH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYCKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCITVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLSDLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYQDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKDWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEASVPVCLYTCL
FTCLSLYLSVCSPVCSPVCLYTCLFTCLSLHLFVYLSVSTPVCLSTCLSLHLSLSAPVCL
FTCMFTCLFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKS
QQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A669F7K2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRCKMFRISEERMQQIQMMTFSEWVQACYSPQLEPA
AVTAITAGVNDAPADLKVIIHFDQSQDSASLKVSLSCTPNELMEQALKKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKDTPHLTLVHTSAVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRRAPTTCVWDVPKPFRIVLVKGSKVNAEETAKVQVRAGLFHGT
ELLCKPAVSNESSGRSEHTWKDNTLEFEISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNP
HINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQ
TNPYTENATALHIHFPEYSSHPIVFPPFDKIKCTFSSYRPSTENPLMGGRGVKKFYMELK
EIMERDPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIWP
KLSPRDALELLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTHF
LLERAQRNRQIGHFLFWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQVEALSKL
KSVNELIKLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDINV
EKCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLD
LRIVPYGCLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDA
LDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKR
ERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLP
ELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A669BDT4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
GQRGMKCTTRGWQAGESYSDCLTQKQCCEVMSHAQSFPLFPALGEMESHMFECVNQAAVH
EELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLDSKIGVLIGKGLHELDALNDQEVKDF
RCKMFRISEERMQQIQMMTFSEWVQACYSPQLEPAAVTAITAGVNDAPADLKVIIHFDQS
QDSASLKVSLSCTPNELMEQALKKWLTTHGSEDAVWRGQYILRVSQCLEFLGGDHPLIQY
KYIRSCLQAKDTPHLTLVHTSAVKTMFDKEISAIGAVVSRKSSNPPLPLPPKRRAPTTCV
WDVPKPFRIVLVKGSKVNAEETAKVQVRAGLFHGTELLCKPAVSNESSGRSEHTWKDNTL
EFEISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNPHINKYQTIPWVNTMVFDYKGQLKTG
DIILHCWSSFPDELEEMLNPIGTIQTNPYTENATALHIHFPEYSSHPIVFPPFDKGRGVK
KFYMELKEIMERDPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQ
ALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYY
DCALTHFLLERAQRNRQIGHFLFWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQ
VEALSKLKSVNELIKLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSV
LLSDINVEKCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLL
WKEANLDLRIVPYGCLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLK
ERNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFK
SKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFAL
MLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAK
DNRS
>A0A8C0W0H4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Castor canadensis|TrEMBL
MELENYDQPVVLREDNLRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRHSKTPETALLH
VAGHGNVEQMKAQVWLRALEISAAADFYHRLGPDSFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRRVPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPEYLLKKIANNCIFIIIHRSTTSQTIKVSADDT
PGIILQSFFTKMAKKKSLMGIPESLNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLIVFVEANIQHGQQVLCQKRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKTPALSGKVSAETHSSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEGD
RVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPEAYPKLFSSVKWGQQ
EIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLL
QLVQVWHVNVTKETILSGNLFACTQAPHSVVSRYSLFRLW
>A0A3P9PLA0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia reticulata|TrEMBL
MDRQQIQVSDEEREVAREESRRRRRKKAITSASSASMDQISVEFVLPTVGRGGSSPDSLL
LEVAGNWTVEQVKAQVWMKAVSLNLCPDFYQRFCPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPTDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPNLYSMDPWVTRKPLPEHLLSKVNNGYILVVIHVSTSSQTIKVSID
DTPSQVLASFFAKTTNKRVLLGIPEHLSDEDFVLRVCGREEYLYGEKALQSFNWIRQSLK
NGEEIHLVLETPPDQELDLVQREDWAQVDDCTGVAGTHEQLTIAEKDHERVFTISMWDCN
RKFRVKVLGIDIPTLPKVPEFTVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKQPQTPNSKSSYHDNTAGSSTLEGKTKNRLLYYVNLLLIDHR
SLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPK
SREVGRDCGASGEEADGGERGQREMPNHLKKQFAAIVSTDPLHPLSPEDKELLWHFRHEC
MRDPRAYPKLLGSVRWGKQEDVLATHRLLDRSNAWDTSGLDVGLAMQLLDCHYSDAQVRS
MAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGENMLQDFRKQVEMTEALQKVTREMKAMSADKYDVTQQ
VVIQLRQKLETLQLSGLPESFRVPYDPGLRAGTLLIEQCKVMASKKKPLWLQFKRADPTT
LSKDPVGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIV
KDATTIATIQQSVVGSTGAFKDEILYQWLRDKCVSEEKFQQAVERFLYSCGGYCVATYVL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKS
SPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSED
EAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A8B7TY19|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Castor canadensis|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPMLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRIPNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQSLAEQPEDYA
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPTPQVQKPR
TKPPPVPAKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMVRLCFALYAVVEKTKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDDKGELLNPVGTVRSNPNTESAAALVICLPEVAP
HPVYYPALEKILELGHHEERGRITEEELQLREILERRGSGELYEHEKDLVWKLRHEVQEH
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLLMEAYCRGSTHHMKVLMKQGEALSKLKSLNDFVKVSSQKTTKPQTKELMHLCMRQ
EAYLEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYGGEEAGSAGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A671VQ62|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MPPAMTDLLDIWAAHSPLAGHALDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRMSEERMQRVQMMTYTEWLQACFSPQLEPT
AGTAITDGLNDRPADLKVIIHFDQSQVRVLSPVQSSCTPMELMELAVRKWLTTHGPEEET
WRGQYVLRVSHCLEFLCGDNPLIQYKYIRTCMQAKEPPHLTLVHTSNVKAMFDKDITAIG
AVVTHKSSNPPLPLPPKRRVPTVSSATRVSVQVRAGLFHGTELLCKPAVSSESSGRSDHT
WKDSTLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNAHINKYQTIRKAGKVHYPIA
WVNTMVFDYKGQLKTGELILHCWSSFPDELEEMLNPIGTIQTNPYTENATALHIHFPEYS
PHSIIFPPFDKILEKAAEILKANDCTRGGKKFHIELKEIMERDALSQLCENEKDLIWTLR
HDCIENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLCPRDALELLDFNYPDQYVREY
AVRCLRDMSNEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGNRKIGHFLFWHLRSEI
HMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSKTKEAM
LTKEAMMTCLRQISYSETLSDLYSPLNPNVLLSGINVEKCRYMDSKMKPLWIVYNNKLLG
GDTLGIIFKNGDDLRQDMLTLQILRLMDRLWKEANLDLRIVPYGCLATGDRAGLIEVVSS
ADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFTLSCAGYCVATYVLG
IGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYT
EKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDDE
ALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7K9FAP2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Stercorarius parasiticus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHQGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQSRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQNWPELPVLNALELLDFSFPDRYVGSFAI
NSLRKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNTILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRS
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>F1NHX1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gallus gallus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLDTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPIKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQVNSIANPPKMA
VKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNVAS
HPVYYPSFEQLLELGRNGEQPRSAPEDPEEKLQLKEILERRNHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLTITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHV
CMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCEKAYMILRRHGPLFLHLFALMKAAGLPELTCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3P8XYR3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPTD
CFSMPSYARRISTATAYMNGETSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLAYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKVNTRDAMVHGML
SNCSVRPLRVHTHVNHIVTICRSCSYNFSNLLNALVARDHALTDIDNEQLRQVSAVNCLA
PLKPTLAYLHTLANIHCLLLFRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAI
KPEQAMELLDCNYPDPMIRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFL
LKRALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLI
NLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNIRLEECRIMS
SAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRM
LLYGCMSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMA
VDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVP
FVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPEL
QSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A2I3MXF6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Papio anubis|TrEMBL
MELENYEQPVVLREDNCRRRRRMKPRSVAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVASDFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPAVSSKASAESHSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRIEKCKVMASKKKPLWLEFKCADPTALSNETIGI
IFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAK
IQQSTVGNTGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHND
NIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQ
DTCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLD
QIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A7J8KEG2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rousettus aegyptiacus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRVPSRALLVNVKFEGSEESFTFQVSSKDVPLSLMACALRKKATVFRQSPVEQPEDYA
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIQLIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVNVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALIICLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEELQLREILERRASGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELAKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPQTKELLHLCMRQ
ETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSEGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A1A8FU29|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius korthausae|TrEMBL
MPPAMTDLLDIWASHSPLAGHALEKITVDFLLPTGIYIQMDVPRDATIQHIKLLLWKQAQ
TFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRITEEKMQQARVMTCTEWLQACCSPQLEPT
AVTFVTDVVNDRPADLKVFIHFDQSQDSTSLKVPMSCTPSELMEIAVKKWLTTHAPEDEA
YSRQYVLRVSQCLEFLCGDHPLIQYKYIRDCLQAKESPHLTLVHTSTVKMLFDKEMSAIG
AVVSRKSSNPPLPLPPKRRPPTQVQTSVWNVSKPFRIDLLKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSDSSGRSEHIWKSNTLKFELSVSDLPRMTRLCFAIYAVTDKVKKQKST
KNAHSSKYQTIRKAGKVLYPIAWVNTMVFDYRGQLKTGDVILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHPVVFPPFDKILEKAAQLVGVIEQPIGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVSCLHDMSDEELLQYLLQLVQVLRYEPYYDCPLTH
FLLERAQRNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSEALSDLTSPLNPSVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLMSGDALGIIFKNGDDLRQDMLTLQILRLMDLLWKESNL
DLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQEGKTGNTEKFGSFRKYCEEAYLILRRNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKNDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A340Y0D6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lipotes vexillifer|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
XXXXFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAIC
TRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKP
EQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLK
KALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINL
TDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSA
KRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLP
YGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAID
LFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFV
LTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQS
FDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C8RZV6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pelusios castaneus|TrEMBL
MPPGIYCPMEFWSKEENQNIHVDFLLPTGIYLNLAVSCNASLGTIKQVVWHHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMSDPEVNDFRAKMRQFCEEKAAKRQQLSWISWMEYNFPLQLEPLVRGSRT
GSLRVPNKNIFVNVKFESGGESFTFQISPKEPPIMLNTYAIKKQATVFRHQKVESPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLLHGQVPHLTMVHCSSIIAMRDEQTNCVAHTTKMA
VKPPPLPKKKPTNESLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGEYCLHMWSSFPDEKGELLNPMGTVQSNPNTESAAALVICFPSVSS
HSVYYPSFEQLLELGRNTEYAHAAPEDLEEKQQLKEILERRNNTELYEHEKDLVWKMRYE
IRDQYPEALAKLLITTKWNKHEDVAQMISLLQSWPELPVLNALELLDFNFPDRYVGSFTI
NSLRKLTNDELFQYLLQLVQVLKYESYLDCELTKFLLERALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSNYHMKVLMKQGEALNKMKALNDFIKVSSQKATKPQAKELMHV
CMRQETYLEALSNLQCPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEESDGGEVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVLHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRD
YCEKAYMILRHNGRLFLHLFALMIAAGLPELSCNKDIQYLRDSLALGKTEEEAMKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A834C827|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias melastigma|TrEMBL
MHPGIYGMLEEWEDGEQEINMDFLLPTGIFLKFPVSRNDTIKHIKEMVWRNARSEALFSG
LGDPDGYVFTCINQTAEREELEEEFRRIRDVKPFMCVLRLVAREGNRQEKLTNTQISLLI
GKGLHDFETQKNHEVNEFRTKMRAFCEEKALERQNLPWQRWLEYSFPCDLEPCRTPSGFG
SVKIKSSKIFINVKFEASDESFMLQQDCHDLPVALMKSALKKKATVFRSLRQEPEDYILQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPQLTMVHHSTVSRFQEEQSRMCNQMFKTRSL
SRPPPLPLKRQNTSSLWSINEPFYIQLLQGSRVNADEGMKLVVQAGLFHGSDLLCKVVTS
LDVTVCSEPMWDQKLEFDINVSDLPRMSRLCFALYAVIEKTKKPKSTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSMWPSVPDDKSDLLNPMGTVEKNPNVESAAGLLIRFPNIRP
HPLYYPSLEKLMDFEKNGDVVYTPKDEHLKLKEIMDNKHYTEFFEDEKDLLWKLRTEIRE
HYPESLSKLLLITKWNKREDVVQVVSLLKKWPDLPAIHALELLDYSFPDPAVRAFTVRCL
RKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASV
SLRFGLILEAYCRGNIHHIKILNKQNEALAKMRALSDFVKSGSQKMTVEDLKLCIRQETY
LEALSDLLSPLNPSIILTDICADKCRFMDSKMKPLWLMYKNPSSPGDMVGVIFKNGDDLR
QDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSA
ATAAFNKDALLNWLKSKNPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYK
ILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDNRP
>A0A8C8VG57|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pelusios castaneus|TrEMBL
MPPAMTDIFDIWAVDSQIGGDGLISVDFLLPNGTYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVQEELEDETQRLCDVRPFLPVLKLITKNCDPGEKLDSKI
GVLIGKGLHEFDALEDPEVKEFRSKMRRISEEKLQSLVGLSWVDWLTHTYPPEQEPSIPE
NFQDKLYGGNLVVAIHFDKCQDVFSFQVSPNINPIKLNEMAIRKRLTIHGKADEVDPSGY
VLQISGRLEYVFGDRPLIQFQQLTQSVWDISNSFKIMLLKGNKLNTEETAKVHVRAGLFH
GTELLCKPIVSAEISGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKT
INPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDLLLHSWTSFPDELEEMLNPMGTV
RTNPYTENATVLHIKFQEYSKLPTYYPPFDKILEKAAEIAKSSDNVGMAGRGGKKFYIEL
KEIMERDPLTQLCENEIDLIWTLRYDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIW
SKLPPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFFDCALSR
FLTERALANRRIGQMLFWHLRSEMHIPAVSIQFGVILEAYCRGSVAHMKVLSKQVEALNK
LKTLNNLIKLNSMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILAELYVEKCKY
MDSKMKPLWIVYNNKMFGGDLVGVIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRVLP
YGCLATGDHSGLIEAVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAI
EEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPF
ILTYDFIHVIQQGKTGNTEKFGRFRQCCEEAYLILRRHGNLFITLFALMLTAGLPELTSV
KDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C9GHR9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Piliocolobus tephrosceles|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAIYAVLDKVKTKKSTKNI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIMLHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSLQALLQIWPKLPP
REALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLER
ALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLN
SLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKM
KPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLA
TGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTL
SCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYD
FIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3Q1CKW5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amphiprion ocellaris|TrEMBL
MPPGKYGMQEEWEKEDQQITMDFLLPTGIFLKFPVSRNDTIKSIKKMVWKNARSEALYSA
LGDPDGYVFTCINQTAEREELEEESRRLSDVRPFMCVLKLVAREGDRVEKLTNTQISQLI
GKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERESLPWQQWMEFSFPCELEPCCAPPESS
SVKPKNSKKIFIQIKFESCQESFMLQQDPQDLPVALMKSALKKKATVFRSVRQEPEDYTL
QVNGRWEFIYGKHPLCQFKYIFSCLRNGQNPHLTMIHHSTIVKYQEEQSKVCSQVSKSGS
LSRPPPLPLKKLVVQAGLFHGSELLCKVVTTSEVTVCSEPLWDQKLEFDINVADLPRMSR
LCFALYAVIEKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDK
SDLLNPMGTVEKNPNIDSAAGLLIRFPNIRPHPLYYPPLDKISDMEKNGDAVYATKDEYT
KLKEIIDNKNSTEFFEDEKELLWKLRTEVRDRYPESLSKLLLITKWNKREDVVQMVSLLR
HWPDLPAISALELLDYSFPDPAVRSFTIRCLKKLSDDELLQYLIQLVQVLKYESYLDCDL
TTFLLERALSNRRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGDIHHIKLLTKQNEAL
GKMKALSDIVKSGSQKMTVDDLKLCIRQESYLDALSDLYSPLNPSIFLADICVEKCRFMD
SKMKPLWLMYLNPSLQGDMMGIIFKNGDDLRQDMLTLQMIQLMENLWKTEGLDLRDKLEQ
AIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERV
PFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFTMMKAAGLPELT
SFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A3Q1BW34|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amphiprion ocellaris|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAYLKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWIISRELGFNYCHTGLSNRLARDNPLTDNDNEQLRQVGNRDPL
SEITEQEKDFLWRHRHDCINMPEILPKILLAVKWNSRDEVSQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQAAMN
>A0A8C2ZVT3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
RELDEEPKVLREDTRRRRRKKAISSSSGASMDQITVEFVLPTAARGGSGPDTLPLEVAGN
WTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDCIRY
WRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPR
RIELSDRDAKLYSMDPWVTRKPLPEHLLTKVSNAHVLMVIHIRTASQTIKVSIDDTPAQV
LVSFFAKTANKRVLLGIPDSMCEADFVLRVCGRFVGDSVFNGWYPTCLKTVFDDVCNPSA
PFRGNNSPANLSLSGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVLGIDIPSLPKIPEF
IVFIEASIFHGQQLLAQERTSSKTFSEEVLWNCWLEFNIKIKDLPKGARLNLQVVCGKQP
LTPNSKGTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATN
PDKASAMAVAILLDKYCYPVVLPKSRNAGNRDDGGRDREMPNHLKKQFAAIVATDPLHPL
SPEDKELLWHFRHECIRDPRAYPKLLGSVRWGRQEDVLATHRLLERSSAWDSSGLDVGLA
MQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALR
SKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTR
EMKAMSADKCDITAQVVFQLRQKLETLQLSGLPESFRVPYDPGLRAGALMIEQCKVMASK
KKPLWLQFKRADPTTLSRDPIGIIFKDGDDLRQDMLILQILLIMESIWETETLDLCLLPY
GCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFKDEILSQWLRDKCVSEDKFQQAVER
FLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVL
TPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKED
IEYIREALTVGRSEDEAERHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A287D7P4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ictidomys tridecemlineatus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSLGA
GNASRLPSRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRRLLVEQPEDY
TLQVNGRHEYLYGSYPLCQFQYICSCMHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKP
RTKPPPIPVKKPSSVSLWSLEQPFCIDLIQGSKVNADERMKLVVQAGLFHGNEMLCKTVS
SSEVSVCSEPVWRQRLEFDINVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIA
WANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGSVRSNPNTESAATLVICLPEVA
PHPVYYPALEKILELGRHGERGRATEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQ
ERFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKS
LRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPS
VALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCM
RQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGSVGIIFK
NGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQL
NKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGY
CERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKF
NEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C7W1A6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRTKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKLVVQAGLFHGSELLCKVVTSGEVNVCSEPLWDQKLVFDISVSDLPRM
SRLCFALYAVIEKAKKPRSTKKKNKKADCPLAWVNTMVFDYKDQLKTGEFLLSTWPSVPD
DKGDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPHFDKPTSYICNHYTCNHLLKE
IVDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKLLLITKWNKHEDVAQMVAFLQKWPD
LPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFL
LERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGNIYHIKSLCKQNEALNKMK
ALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLLSPLNPSIMLSEICADRCKFMD
SKMKPLWLMYKNKWVQGDTVGIIFKNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYG
CLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEE
FTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFIL
TYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKD
IQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDSRL
>I3LY96|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ictidomys tridecemlineatus|TrEMBL
MCFSFIMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRIFSEEKIQSLVGLSWIDWLKQTYPPEH
EPSTLENLEDKLYGGKLIVAVHFENCQDVFSFQVSPEMNPIKINELAIQKRLTIHGKEDE
ASPYDHVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECSKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNELLEFDINICDLPRMARLCLAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVASRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LSPRDALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C9WQK8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MAPGVYCLPNMWEGGVQQVKMDFLLPTGIYLSFGVSGNDTIGTLWRNAKNEPLFFALSDP
DAYVFTCINHTAEQEELEDEQRRLCDVRPMMPILRLVAREGDRVEKLITSQISLLIGKGV
HEFDTMKNHEVNEFRTKMRTFCEELAMDRQRLPWQKWIEYSFPCDLEPCALLSHSGNLRN
RASKKIIVNVKFEASDESFTLQVEPQEVPLTLMKSALKKKATVFRPMKQEKPEDYALQVN
GRWEFIYGNFPLCQFKYIFNCLHSGVTPHLTMVHYSTITKYQEEQGGISREISKNRSSSK
PPPLPLKKQTMSSLWSIQDAFSIHLMHGSRVNADEGMKLVVQAGLFHGSELLCKVVTSSE
VNVCSEPVWDQKLEFDINVCDLPRMTRLCFALYAVIEKSKKPRSTKKKNKKADCPLSWVN
TMVFDYKDQLKTGEYYLSTWPSVPDDKTDLLNPMGTVEINPNTDSAAGLLIRFQNVRPHP
IYYPSLDKQGTYPRIAPVKITQLEIVENKNYTEFFEDDKEILWKLRYEVREKYSESLSKL
LLITKWNKHEDVAQMVSLLQKWPDLPALHALELLDYSFPDRNVRSFTIRCLRKLSDDELF
QYLLQLVQVLKYESYLDCDLTKFLLERALSNKKIGHFLFWHLRSEMHVPSVNLRFGLILE
AYCRGSIYHMKTLMKQNEALNKMKSLNDFVKSASQKGTRTQTTGEMKKCIKQETFMEALS
DLLSPLNPSLILSEICPDRCKYMDSKMKPLWLVYKNEKVQGDPLGIIFKNGDDLRQDMLT
LQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAF
NKDALLNWLKSKNPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHI
DFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYKILCRN
GTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTK
VNWMVHSVSKDNR
>A0A8C2Y812|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coturnix japonica|TrEMBL
MELDENEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTNNKHTKVPETVLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGDTPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEDQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIVQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKDRCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A5N5LGX3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pangasianodon hypophthalmus|TrEMBL
MEQHVSDDESPVVLRSETRRRRRKMKAFTSNSSVAMDHLALEFVLPTTNKTTRNPDTLQL
DVIGNWTVEQVKAQLWLKAVTTNVCPEFYQKYSPDHCILLYQKKGSWCEIYDKHQVFQTL
DCIRYWKALKKEVGKIHLVLRQQPSEESVQYQKFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTTRKIELVDREPKLYSMDPWITTKPLPDYLLSKITNNHILIVIHRDTSSQTIKVSIDD
TPFQVLQSFFIKTTNKRALLGIPEDVNESDFVLRVCGREEYLFGNYPIKDFHWIRQCIKS
GEEIHLVLESPPDPEQDVVQKEDWSQVDDCTGVAGTHEQLTINEKDHEKVFTVSLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTSSKPFTEEVLWNTWLDFNIK
IKDLPKGARLNLQVSCGKAQTQTSKDNISHDCKNKSRLLYYVNLLVVDHRSLLRQGEFIL
HMWKMPEKSEDNSSVNADKLTSATNPDKTSSMAIAVLLDKYCYPVALPKSRDSRDTSEME
GERGKREMPNHLRKQFDQIVATDPLHPLSAEDKELLWHFRQECVRHPTAYPKFLGSVKWG
KQEAVMATHHLLERSTTWDRSPLDVGLAMQLLDCHFSDANVRTMAVRKLETLGDDDVLRY
LLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEA
YLRGCGDAMLQDFRKQVEITEALQKVTREVKAISAEKYDVSAQVVFQLRQKLESLQMQGL
PESFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLR
QDMLILQILLIMESIWETESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNT
GAFKDEILNQWLRDKCLNEEKYQQAVERFVYSCGGYCVATYVLGIGDRHNDNIMITESGN
LFHIDFGHILGNYKSFLGITKERVPFVLTPDFLYVMGTTGKKTSPNFLMFQNICVKAYLA
LRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGCTEDVAQRHFLDQIEICRDKG
WTVQFNWFLHLVLGIKQGVEKRSA
>A0A7K9TF63|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Galbula dea|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCISSNLSSMELISIEFILPTSNKHTKVPEIIVLE
IAGNCTVEQMKAQVWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQTPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PEMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKGKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIITTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKDVWDQSTLDVGLTMQLLDCNFSDESVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C2TQ22|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coturnix japonica|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGAIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLSHTPVKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQVSLLSCFDKRVCPPCTHFSGRVVDGSADEMSSARQVTFLA
MPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSS
EVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWV
NVMLFDYKDQLKTGECCLHMWSSFPGMSGANAAVSVSSSCHRDGILTYCPLYALCCDSHE
QKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLTITKWNKHEDVAQMIS
LLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLD
CELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQG
EALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQETYLEALSHLQSPLNPSIILTEVCV
DQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLD
LRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDA
LEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINR
ERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYMILRRHGPLFLHLFALMKAAGLP
ELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>R0JDE3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos|TrEMBL
IMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHS
YPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSK
IGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIP
ENFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEDIDPA
DYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAI
NRKSSNLPLPLPPKKTRATTSVWDVCSPFKITLLKGNKLNTEENAKVHVRAGIFHGTELL
CKTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSK
YQTIRKAGKVHYPVAWVNTMVFDYKGQLRNGEFVLHSWSSFPDELEEMLNPMGTVQTNPY
IENATALHIKFQEYSKHPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFFVVLKEIME
RDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLP
REALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLER
ALANRRIGQMLFWHLRSEVHIPAVSIQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLN
SLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKM
KPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLA
XXXXSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTL
SCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYD
FIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A672ZVC9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
SWCTNYFLQCPVVLREENRRRRRKKAITSSSCTSMDQIAVEFVLPTAARGGNSPDTLQLE
VAGNWTVEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLD
CIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKL
LTQRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVCNGFILVVIHISTASQTIKVSIDDT
PAQVLSSFFTKTANKRVLLGIPENTGEKDFVLRVCGRYKEYLYGDKPLQNFNWIRQCLKN
GDEIHLVLETPSDPEADLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNR
KFRVKVLGIDIPSLPKVPELVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIK
IRDLPKGARLNLQVNSICCLSGKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSE
ESSSSSINADKLTSATNPDKASSMAITILLDKYCYPVVLPKSRDVCRDGGTWGEEAEGGE
RGQREMPNHLKKQFEAIVATDPLHPLSPEDKELLWHFRHECMRHPRAYPKLLGSVRWGKQ
DDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLL
QLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYL
RGCGEAMLQDFRKQVEMTEALQKVTREIKAMSADKYDVTAQVVFQLRQKLETLQLSGLPE
SFRVPYDPGLRAGTLLIEQCKVMASKKKPLWLQFKRADPSTLSKDPIGIIFKDGDDLRQD
MLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGA
FKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLF
HIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALR
HHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRCEDDAQRHLLDQIEICREKGWM
VQINWFVHLVLGIKQGVEKRST
>A0A8C3LRL5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysolophus pictus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINSIANPPKMA
VKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALLICFPNVAS
HPVYYPSFEQLLELGRNGEQPRSQKLQLKEILERRSHTELYEHEKDLVWKMRHDIRDQYP
QALAKLLTITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAINSLKKL
TDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALR
FGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQET
YLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDL
RQDMLTLQMIQLMDVLWKQEGLDLSDALEQAIEEFTLACAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
EKAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q1J789|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPGKYGMQGEWEKEGDHEIMMDFLLPTGIFLKFPVSRNDTIKTIKRMVWKNARSEALFT
ALGDPDAYVFTCINHTAEREELEEESRRISDVQPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEVQKNHEVNEFRTKMRVFCEEKAQERQRLPWHQWMEYSFPCDLEPCCSPQCG
SSRSKNTKKILINIKFEASDESFMLQQDPQDPPLVLMRSALKKKATVFRSVRQEPEDYTL
QVNGRWEFIYGNHPLCQFKYIFSCLRNGQNPHLIMVHHSTISKYQEEQGRMCNQVYKSCS
LSRPPPLPLKKQNTSSLWSINEPFCIHLVQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SSEVTVCSEPLWDQKLEFDINVADLPRMGRLCFALYAVIEKAKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVERNPNVDSAAGLLIRFANIR
PYPLYYPPLDKISDVERNGDATTGTKEEFVKLKEIMDNKNYTEFFEDEKELLWKLRAEVR
SSYPESLSKLLLITKWNKREDVVQMVSLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRC
LRNLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVAS
VSLRFGLILEAYCRGNIHHIRLLTKQNEALAKMKSLSDFVKSGSQKMTVEDLKLCIRQES
YLEALSDLLSPLNPSIILSGICADKCRFMDSKMKPLWLMYKNPGTQGDMVGIIFKNGDDL
RQDMLTIQMIQLMENLWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNCSNS
AATAAFNKDALLNWLKSKNPGDKLDQAIEVFTLSCAGYCVATYVLGIGDRHNDNIMIRET
GQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAY
KILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLCLGKSDDEALKNFKVKFNEALR
ESWKTKVNWMMHSLAKDNRP
>A0A7N6AV49|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPAMTDLLDMWAAHSPLAGQTPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
NFPLFPALGEMESHMFECVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRISEEQMQRVQMMTWKEWLQACFSPQLEPA
AGTAITDGVNDRPADLKVTIHFDQSQDSASLKVPATCTPLEVIELSMRKWLTTHGPEEEE
WRGQYVLRVSHCLEFLCEEISLFQYKYIRTCMQAKEPPHLTLVHTSSIKQMYDKEISTIS
AVVSRKSSNPPLPLPPKRRVPTQLQTCVWDVPSPFKIVLVNASKVNAEETVQVRAGLFHG
AELLCKPAVSSESSGRSDHTWKENTLEFDIFVNDLPRMTRLCIAIYAVMDKVKKQKSTRN
AHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTI
QTNPYTENATALHIHFPEYSSHPIVFPPFDKVRHFSVIARIFLYHLFSQGRGGKKFYIEL
KEIMERDPLSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLCPRDALELLDFNYPDQYVREYAVGCLRDMSDEELLQYLLQLVQVLRYEPYYDCALTH
FLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRCNIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLQSPLNPNVLLSGIN
VDKCRYMDSKMKPLWIVYNNKLLAGDNLGIIFKNGDDLRQDMLTLQILKLMDLLWKEANL
DLRIVPYACLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7K8UR52|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ciccaba nigrolineata|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIAGPPKLA
AKPPPLPKKKPNYGSLWSLERSFYVELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQTRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8J6A8N9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Galemys pyrenaicus|TrEMBL
IGTMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYP
LHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREI
GFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPEL
PKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSE
QLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQL
PMDCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVR
TGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKE
EHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEF
DWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAVLITHEYKGGNIGKENYVKYYFILQS
NRLARDNELRENDKEQLRAICTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKW
NSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQ
LVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRA
CGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSP
LNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTL
QIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNS
HTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDF
GHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQH
ANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTK
MDWIFHTIKQHALN
>A0A7K5RCS5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lanius ludovicianus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKIINNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTSLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPVALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K6QJW8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Climacteris rufus|TrEMBL
MELEDHEQTVVMREENKRRRRRMKPHCTSSNFSSMEMISIEFILPTSNKHTKVPEMLSLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQAFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERIFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLDDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITEA
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>G3N8C1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gasterosteus aculeatus|TrEMBL
MGPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQNGQEESSYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREI
GFAIGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNLESSPQL
PQHIYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQ
QLRLCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQL
PASGFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIY
VRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLAYDIYLADIPRSARLCLSICSVKGRKGA
KEEHCPLAWGNVNMFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVEL
EFSWFNQTVVFPDEQQIEEHANWTISRELGYNYCHGVSSRLACDSRTSVADTEQLCSLCS
RDPLYELSEQEKDFLWRHRHYCVNMPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPE
SALELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKK
ALTNQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLT
DTLKQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAK
RPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPY
GCLSIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDL
FTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVL
TQDFLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSF
DDIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPN
>A0A8C2NVJ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Capra hircus|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASLNSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPRLYAMHPWVTSKPLPEYLLKKITNNCVFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQVIASLLPACW
EHRPGGAAALPSHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAALPSHFALSLLL
PLPTRLSHGSPAPHDHPPPSLFCPFPKRKIMLLSHPLLKPNSK
>A0A7N8YA16|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPAMTDLLDIWAAHSPLAGQAPAHITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINEQEVKDFRSKMFRFSEERMQRVQMMTCTEWLQSCFSPQLEPA
AGSAITDGVNDRPSDLKVIIHFDLSQDSISLKVPSSSTTMELIELAVRKWLTTHGPEEET
RRGQYVLRVSHCLEFLCGDHPLTHYKYIRICMQAKESPHLTLVHISTIKGMFDKEISTIR
AVVTRKSCNLPLPLPPKRRVPTVSPGTCVWDVSSPFKIVLVNCSKVNAEETVQVRAGLFH
GTELLCKPAVSSESSGRSEHTWKESTLEFEISVSDLPRMTRLCFAIYAVMDKVKKQKSTK
NAYINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGT
IQTNPYTENATALHILFPEYSSHPIVFPPFDKILEKAAEIAGASDCAPMGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVCCLRDMSDEELLQYLLQLVQVLRYEPYYDCALTH
FLLERAQGNRKIGHFLFWHLRCVHKNVKASAKLNLEIIEMMKYCSGANMIHPYQVEALSK
LKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVMLSDIN
VEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEASL
DLRIVPYGCLATGDRAGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKSDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A0D9S8P7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chlorocebus sabaeus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANFMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7N8XJ78|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSRNDTIKLVWKNARSEALFTALGD
PDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFEAQKNHEVNEFRTRMRQFCEEKSQERQMLPWQQWMEYSFPCDLEPCCSLPSTKSRN
TKKIFINIKFEACDESFMLQQDPQDLPVALMKSALKKKATVFRSVRLEPEDYTLQVNGSW
DFIYGKHPLRQFKSRPPPLPLKKNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLF
HGSELLCKVVTSSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTK
KKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSA
AGLLIRFPNIRPHPLYYPPLKVSPLTATKEEHQKLKEIMDNKNYTEFFEDEKELLWKLRY
EVCSLYPESLSKLLLITKWNKREDVVQMVGLLRNWPDLPAIHALELLDYSFPDPAVRFFT
IRCLKKLSDNELLQYLIQLVQVLKYESYLDCDLTTFLLERALANRRIGHFLFWYLRLDTF
AFWADPGSLLLKLLDDLKLCIRQESYLEALSDLLSPLNPSIILAEICAHKCRFMDSKMKP
LWLMYGNPWAQGEMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMSPYGCLSTG
NKMGLIEAVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSC
AGYCVATYVLGIGDRHNDNIMIRENGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFV
HVIQQGRTNNSEKFERFREYCERAYKILCRNGMLFVNLFAMMKAAGLPELSSFKDIQYLK
DSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A7K5INI3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Toxostoma redivivum|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEDKVAKRQQLSWAAWMEYNFPLQLEPMAKGLGA
GSLQIPTKNIFVNVKFQSGGESFTFQISPREFPITLMSYAIRKQATVFRHETLQKPEDYT
LQVNGKCEYLYGNYPLFQFQHIRSCLQRGLTPHLTMVHCSAILAMRDEQNNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELLQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWRQRLEFDISVSDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRMK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2D0SKR1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ictalurus punctatus|TrEMBL
MPPGVYCDLQDVWEKEGREQVTMEFLLPTGIYLSFPVAGSDTIATIKKMLWKNARSEPLF
SILSDPDAYVFTCINRTAEREDLEDEQRRLCEVRPFLPVFRLVAREGDRVEKLINTQISL
LLGKGLHEFDTQKNHEVNEFRTKMRSFCEEKAQERQRLPWHQWMEYNFPCDLEPISVGAQ
SGKSHINVKKIFINVKFEASEESFMLQLDPQDLPLVLMKSALRKKATVFRPVKQEKPEDY
TLQVNGRWEFIYGKYPLFRFKYIFSCLYGGLTPHVTMVHHSTIAKYQEEQGGLSNQVSKS
RSQSKPPPLPLKKQNTSSLWSIQEPFYIHLLHGTRVNADESMKLVVQAGLFHGSELLCKV
VTSGEVSVCSDPVWDQKLSFDVNLCDLPRMTRLCFALYGVLDKPRKQRSTKKKNKKADCP
LAWVNTMLFDYKDQLKTGDIFLSTWPSAPDDKGDLLNPMGTVERNPNMDSSAGLLIHFAS
FRPHPLYYPPLEKLTEINGEKAVATKEENLKLKEIVDNKNHTEFFEDEKELLWKLRGEVR
AKYPESLSKLLLITKWNKHEEVAQIVALLRKWPDLPALHALELLDYSFPDPHVRSFTIRC
LRKLCDDELFQYLLQLVQVLKYEPYLDCDLTTFLLDRALSNKRIGHFLFWHLRSELHVPS
VGLKFGLILEAYCRGSIYHMKSLMKQNEALSKMKALNDFVKSGSQKSVSRSQITEDMKLC
IKQDTYLEALSGVVSPLNPSIILSEICTDSCKFMDSKMKPLWLMYKNKCVQSDTLGIIFK
NGDDLRQDMLPLQMIQLMDILWKTEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQR
NKSNSAATAAFNKDALLDWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRENGQLFHIDFGHFLGNFKAKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREC
CEQAYKILCRNGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGRSEEEALKNFKVKF
NEALRESWKTKVNWMMHTFAKDNR
>A0A8D0Y7P8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRFGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQVNGFPFDHLL
GIPTRGACSPHLSLPFEAPLPCAHLLPISSVPSPSPK
>A0A8C0K4U5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus dingo|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNDFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPNDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKNI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNKAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8B7QFQ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hipposideros armiger|TrEMBL
MELENDEQPVVLREDNRRRRRRMKPRGSAASLSSMELIPIEFVLPTSQRTSKTPETVLLH
VASHGNVEQMKAQVWLRALEISVAADFYHRLDPNHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHSPSEETLAFQRQLTALMGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPRLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGIILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPAQDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVLVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIFCGKAPALSGKASAETPSSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDHGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLRHPKAYPKLFSSVKWGK
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQVGDACVIHRVLFFARGCTSPQCVFIVFRKHLTASLQVEKCKVMASKKKPLWLEFK
CADPTALSNETIGIIFKHGDDLRQDMLILQNGNNHHIYTIGLMQRIDIKQHSGEVDEVIS
QLKQKLENLQNSSLPESFRVPYDPGLKAGTLVCHVNSNTARWSSPYLVTITTITAFSSFQ
DVCAKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLD
QIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A8B7T4F1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hipposideros armiger|TrEMBL
MEIKGYDIFKMLWKQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLP
VLKLVTRSCDPGEKLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLS
WMDWLKQTYPPEHEPSILENLEDKLYGGKLIVAVHFESCQDVFSFQVSPNMNPIKVNELA
IQKRLTIHGKEDEVSPCDYVLQISGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECY
KIKKMYEQEMIAIEAAINRNSSNLPLPLPPKKTRTISHVWENNNPFQIVLVKGNKLNTEE
TVKVHVRAGLFHGTELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYTV
LDKVKTKKSTKTINSSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPD
ELEEMLNPMGTVQTNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVS
SRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLED
VAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLK
YEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVHIPAVSIQFGVILEAYCRGSVGHMK
VLSKQVSTCFNIHVQFVTWYLMSCIICFYCHFIISYRFNRLIFPLFDFSVEKCKYMDSKM
KPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLA
TGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTL
SCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYD
FIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A0F8ABY6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Larimichthys crocea|TrEMBL
MPPGKYGMQEEWEKEGDQGIVMDFLLPTGIFLKFPVSRNDTIKSIKKMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEESRRICDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERQMLHWQQWMEYSFPCDLEPCCSLPVC
ASAKSKNSKIFINVKFEASDESFMLQQDPQDFPVALMKSALKKKATVFRSVRQEPEDYTL
QVNGTWEFIYGKHPMCQFKYIFSCLRNGQNPHLTMVHHSTISKYQEEQGRMCSQAYKSRS
LSRPPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFHNIR
QHPLYYPPLDKISDVEKNGDAPFATKEEYMKLKEIMDNKNYTEFFEDEKELLWKLRAEVR
NHYPESLSKLLLITKWNKREDVVQMVSLLRNWPDLPGIHALELLDYSFPDPTVRSFTIRC
LRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVAS
VSLRFGLILEAYCRGNICHIKLLTKQNEALGKMKALSDFVKSGSQKMTVDDLKLCIRQES
YLEALSDLLSPLNPSIILAEICADKCRFMDSKMKPLWLLYKNPLAQGDMVGIIFKNGDDL
RQDMLTLQMIQLMENLWKKEGLDLRMIPYACLSTGNKMGLIEVVKNSDTIANIQRNSSNS
AATAAFNKDALLNWLKSKNPEEKLDKAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRET
GQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRGYCERAY
KILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKVNWMMHSLAKDNRP
>G1RDT2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nomascus leucogenys|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQYGLHPLLWHRAQY
EPLFHMLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINS
QISLLIGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSA
RTWGPGTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQ
PEDYTLQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPGKKPSSVSLWSLEQPFCIELIQG
SKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARL
CFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKG
ELLNPTGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKLLGGMLLASGGWRPELLWMC
LHAQDSAPSRMIGVAMPCLGVLPGLVQAPRDAECSCLLQILELGRHSECVHVTEEEVSGV
GVCGEILERRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNRHEDVAQMLYLL
CSWPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCE
LTKFLLDRALANRKIGHFLFWHLRYSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGE
ALSKLKALNDFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVE
QCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLD
LRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEA
LDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINR
ERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLP
ELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>G1R165|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nomascus leucogenys|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKVKSNADA
YYFIEIILYNLFLELYSNLWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLA
WGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSV
VKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEI
TEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLD
CNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRI
GHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEK
KDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNW
ENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGD
CVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAG
YCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIV
ISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIR
KTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A0S7K0G9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poeciliopsis prolifica|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLINIKQQLFIEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIMSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLENFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCENVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVSLFDYMDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
RFSQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSATDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCLNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDRVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNHGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLMLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A8B9WWE4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus grunniens|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASMSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQIVSSMRTGTA
SVFLTTRLP
>A0A0S7FJH8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poeciliopsis prolifica|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
NFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERQLD
SKIGVLIGKGLHELDGINDQEVKDFRSKMSRLSEEKMQRVQMMTCNEWLQACFSPQLEPA
ALTTITDGLNDRPADLKVIIHFDQSQDSTSLKVLSSWTPSELMEMAVKKWLVTHAPEEEE
WSGQYVLRVSHCLEFLCGDHPLIQYKYIRTCLQAKEPPHLTLVHTSTIKEMFDKEMSAIS
AVVSRKSSNPPLPLPPKRRIPTQAQTCVWDVTSTFRIVLVKGSKVNAEESAKV
>A0A8B9MFF8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Accipiter nisus|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSVSVDFLLPTGIYIKLDVPRDATISHIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWRDWLKHTYPPEQEPVIPE
SFQDKLYSGNIVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAE
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHIWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIKFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNN
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRDDLDRAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEDEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K6JXN5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreocharis arfaki|TrEMBL
MELEDHEQPVVMREENKRRRRRMKPHCTSSGFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQVWMRAIEKSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDVKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKREAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSPLARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPGSFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C0SKE3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MEPQGREPRVVLREDHRRRRRRMKARGPAAGLPSMELIPIEFVLPTSQRSSKAPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYQRLGPDHFVLLYQKKGQWYEIYDRYQVVQTLD
CLRYWQLLHRSPGQIHVVQRRAPSAATLAFQRQLTALIGYDVTDLSNVHDNELEFTRRRL
VTPRMLEVAGRDPELYAMHPWVTSKPLPDYLRKRIPNNCVFIVIHRGTTSQTVKVSADDT
PGAILRSFFAKMAKKKALMGIPEGQSERDFVLRVCGRDEYLVGDTPLQNFQWVRQCLKNG
EEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRR
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFSIKI
KDLPRGALLNLQVYCSKAPTLSAKASADAPGAGSEARGKAQLLYYVNLLLIDHRFLLRRG
EYVLHMWQISGKGEDQGSFNADKLTSATNDKENSMSISILLDNYCHPIALPKHRPTPDPE
GDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWG
QQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHY
LLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLEA
YLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNL
PESFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLR
QDMLILQILRIMESIWETESLDLYLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNT
GAFKDEVLNHWLKEKCAIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGN
LFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLA
LRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKG
WTVQFNWFLHLVLGIKQGEKHSA
>A0A7L0HZS6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Arenaria interpres|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMTKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGDQPRAALEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDNELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A5N3UXS5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Muntiacus muntjak|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
SLRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGAVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A091G1E2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cuculus canorus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLVKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSCAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGIPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>W5N7Y0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lepisosteus oculatus|TrEMBL
RRLCDLRLFHPILKVIEPVGNREEKILNREIGFAIGMPICEFELVKDPEVQDFRRSILSV
CREAMEEREGGGAHSQALYVYPPNVESSPELPQHIYCKLDKGRLIVTIWVIVSPSNDKQK
YTLKTPHDSLPEQLIAEAIRKKTRSMHLSPEQLRLCVQEYQGQYILKVCGCDEYLLEKYP
LSQYKYIRSCITIGRLPHLMLVSKDSLYSQLPASGFVTPSYSRRTPQPSPCLGGADPSPP
RPLWAFSSPLRVRLLCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWN
EWLTYDIPLFDLPRSARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYKDTLVNGKITLG
LWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFPWFSHAVRFPDEQQVEEHANWTISREL
GYNCCLLGMSNRLACDSSVSQTDVDQLRSICSRDPLYELSEQEKDFLWRHRHYCVNIPES
LPKLLLSVKWNSRDEVSQLTPLSLRSEMHNKTVSRRFGLLLEAFCRGCGMYLKHLNRQVE
AMEKLINLTDTLKQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVCPLNPVHQLGNLRLE
ECRIMSSAKRPLWLNWENPDIMSELLFTNNEIIFKNGDEITHKSRELRDDPLNGEVTQAA
GMDCLCQXYGCLSIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRG
EAYDRAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGY
KRERVPFVLTQDFLIVISKGTPECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSLLLG
CGMPELQSFDDIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPN
DH
>A0A7K7IZY3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Loxia curvirostra|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPATMGLSS
LQIPTKNIFVNVRFQSGGESFTFQISPWEFPITLMSCAIKKQATVFRHETVQKPEDYTLQ
VNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGAEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8B9D191|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anser brachyrhynchus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7E6CIL4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phyllostomus discolor|TrEMBL
MELENNEQPVVLREDNCRRRRRMKPRGSAASLSSMELIPIEFVLPTSQRTSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVVADFYHRLSPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHSPSEESLAFQRLLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPAQDEVKKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQVYCGKAPALSGKASADIPSSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSICILLDNYCHPIALPKHRPTPDPEG
DRIRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLSRREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRALRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGAAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVILQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSKETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQ
>A0A7L3YVR1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fregetta grallaria|TrEMBL
MELGDYEQPVIMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTCNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQILYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K7F1F6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chionis minor|TrEMBL
MPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GPLHTPAKNIFVNVRFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLMPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSFWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSQKATKPQTRELMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A673XBK9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPAMTNLMDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQQVQLMTWSEWLQACFSPQLEPGGG
ATPVTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISA
IGAVVNRKSSIPPLPLPPKRRGPSVSTHFKIVLIKGSKVNAEETAKVQVRAGLFHGTELL
CKPAVSSESSGRSEHVWNSTLEFDITVSDLPRMTRLCFAVYAVMDKVKKQKSTKNAHINK
YQTIRKSGKVHYPVAWVNTMLFDYKGQLKTGDIILHSWSSFPDELEEMLNPIGTIQTNPY
TENTTALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCLPMGRGGKKFHIELKEIMER
DPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQVHTVPHEPVLCIDS
GTKLVDEELSQYLLQLVQVLRYEPYYDCALTRFLLNRAQCNRNIGHFLFWHLRSEMHMPA
VAVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSKTKEAMLTKE
AMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMDSKMKPLWIVYNNKLLGGDTL
GIIFKNGDGTRGCISMVLIMNHWNKMCLCRIVPYGCLATGDRSGLIEVVSSADTIANIQL
TSSNVAAAAAFNKDALLNWLKEKNSGDALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRNY
CEQAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKF
DEALRESWTTKVNWMAHNVVKDNRS
>A0A8C3RWN3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelydra serpentina|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVCPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWAINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMTVIEEHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYSVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C3T393|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelydra serpentina|TrEMBL
DFLLLWKQAHSYPLFHLLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLKLVTR
NCDPGEKLDSKIGVLIGKGLHEFDALQDPEVKEFRSKMRRISEEKLLSLVGLSWLDWLKH
SYPPEQEPSIPENFQDKLYGGNLVVRPLGSGNSCRKGVSPNINPVKLNELAIRKRLTIHG
KEEEVDPYDYVLQISGRLEYIFGDHPLIQFQYIRKCVMNRTLPHLTLVECCSIKKMCEQE
MIAIEKIISKKNFQPALMFLSKYSWHVFGYFSVTPLLQVHVRAGLFHGTELLCKPIVSAE
IFGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKTINPSKYQTIRKHY
PVAWVNTMVFDFKGQLKSGDFLLHSWTSFPDELEEMLNPMGTVRTNPYTENATALHIKFQ
EYSKLPIYYPPFDKGRGGKKFYIELKEIMERDPLTQLCENEMDLIWTLRYDCRENFPQSL
PKLLLSIKWNKLEDVAQLQALLQIWSKLPPREALELLDFNYPDQYVREYAVGCLKQMSDE
ELSQYLLQLVQVLKYEPFLDCALSRFLVERALANRRIGQMLFWHLRSEVHIPAVSVQFGV
ILEAYCRGSIAHMKVLSKQVEALNKLKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYRE
ALSDLQSPLNPSVILSELYVEKCKYMDSKMKPLWIVYNNKMFGGDLLGIIFKNGDDLRQD
MLTLQILRLMDLLWKEAGLDLRMLPYGCLATGDHSGLIEAVSASETIADIQLNSSNVAAA
AAFNKDALLNWLKEYNLGDDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQL
FHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLIL
RRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESW
TTKVNWMAHTVRKDYRS
>A0A7J6AK56|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ameiurus melas|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKFPLHH
LLQEEASYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESSPELPKH
IFGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMD
TFTMPSYSRRISTATPYMNGEASSKSLWTINSNLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLMYDMYIHDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SCPVKFPDMTTIEDHANKIMSREMGYNYFQSGQSSRQARDHHIMEGDIDQLRQVANRDPL
SEITEQEKDFLWRHRQYCKNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIREFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLGRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGETYDLAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A7L2I0M2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sagittarius serpentarius|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFAKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWVRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPSSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSN
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A151M6C3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alligator mississippiensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWSLNSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMFILELPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMTVIEEHANWAIARELGCNYSHAGLSNRLARDIEVRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHNCVNTPEILPKLLLSVKWNSRDEVTQMYCLIKDWPPIKPEQAME
LLDCNYPDPMVRSFAVQCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A2K5TKS9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca fascicularis|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPAKKPFSVSLWSLEQPFCIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDIHICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNP
TGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKLLGGMLLASRGWRPELLWICLHARD
SAPSRMIGVATPCLGILPGLVQALGDAECSCLLQILELGRHSECVHVTEEEQLQLREILE
RRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQDALPAVSWPELPV
LSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDR
ALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3B4EWL3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pundamilia nyererei|TrEMBL
MAPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLTTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYSKLDKGQIIVVIWVIVSPTNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMD
FFTMPSYARRISTATPYMNGETATKNLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLTYDMYIPEVPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHY
SSAVKFPDMSTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDGDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHDCINMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMVREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A3B4FZL5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pundamilia nyererei|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVMRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRSKMFRISEERMQQIQMMAFSEWVQACYSPQLEPA
AVTAITAGVNDAPVDLKVIIHFDQSQDSASLKVSLSCTPNELMEQALKKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKEAPHLTLVHTSTVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRRIFCLSLHLWPLAGWLVIIKFNPSCRTQVQVRAGLFHGTELL
CKPAVSNESSGRSEHTWKDNTVEFEISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNPHIN
KYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATALHIHFPEYSSHPIVFPPFDKILEKAAEMVSADCVSIGRGVKKFYMELKEIMER
DPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPR
DALELLDFNYPDQYVREYAVRCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERA
QRNRQIGHFLFWHLRSEIHMPAVSVQFALLLEAYCRSNIPHIEVLKKQVEALSKLKSVNE
LIKLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDINVEKCRY
MDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVP
YGCLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAI
EEFTLSCAGYCVATYVLGIGDRHSDNIMVRSNGQLFHIDFGHILGNFKSKFGIKRERVPF
ILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSV
KDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A3B4GEG1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pundamilia nyererei|TrEMBL
MDRQQIQVSDEECQVPREESRRRRRKKAITSSCSTSMDQISVEFVLPTAARGGSGPDTLQ
LDVAGNWTVEQVKAQVWMKAVTSNLCPEFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTRKPLPEHLLSKINNGHILVVIHIGTASQTIKVSID
DTPTLVLASFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLK
NGEEIHLVLEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNI
KIKDLPKGACLNLQVICGKQPQTPNSKGSSYQESTAGSSCLDGKTKSRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLP
KSRDVGRDWAVGGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHE
CMRDPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVR
SMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSKHYQQRYAVLLEAYLRGCGENMLQDFRKQVDMTEALQKVTREIKTMSADKYDVTP
QVVFQLRQKLENLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADST
TLSKDPIGVIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKK
SSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSE
DEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A8C5J345|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Junco hyemalis|TrEMBL
MPPGIYCPTEFWSKGENQSIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAVFNDCF
MFQISPWEFPITLMSYAIKKQATVLRPETVQQPEDYTLQVNGKCEYLYGNYPLYQFQYIR
SCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASKPPPLPKKKVRGDRDPWAPLAQ
AVPRAHGAVLAVPQLVVQAGLFHGTEMLCKTVSSSEVSVCSEPVWRQRLEFDISVRDLPR
MARLCLALYAVVEKARKARSTKKKSKKADCPIAWANVMLFDYRDQLKTGECCLHMWSSFP
DEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHPVYYPSFDPECALAVQKLQLKEILE
RRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNRHEDVAQMISLLQTWPELPV
LNALELLDFSFPDRYVGCVSCFLSVLRDDDVFQYLLQLVQVLKYESYLDCELTKFLLERA
LSNRKIGHFLFWHLRSEMHVPAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALND
FVKVSSQKATKPQTKEMMHMCMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMK
PLWIVFNSEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLST
GDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDF
VHVIQQGKTNNNEKFERFRGYCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYL
KDSLALGKTDEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C6NF11|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Melopsittacus undulatus|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETQRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVHDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRHCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRTTTSVWDISNPFKITLLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSPEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKVKTKKSTKAMNTSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGEQVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVSCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMQTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C6K1F4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Melopsittacus undulatus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GPFHIPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKTA
AKPPPLPKKKPNYGSLWSLEQSFYIQLVQGSKVNADEGMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWQQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPPLSCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLSDALEQAIEEFTLSCAGYCVATYVLGIGDR
HSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFE
RFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKH
FRLKFNEALRESWKTKVNWLAHNVSKNNRQ
>A0A1A6HJ32|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neotoma lepida|TrEMBL
MADILDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQTAVYEELEDETRR
LCDVRPFLPVLKLVTRSCDPAEKLDSKIGVLIGKGLHEFDALKDPEVXEFRRKMRKFSED
KIQSLVGLSWIDWLKHTYPPEHEPSVLENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNL
TPIKINELAIQKRLTIHGKEDEASPYDCVLQVSGRVEYVFGEHPLIQFQ
>A0A671F0L9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinolophus ferrumequinum|TrEMBL
MCFNFIMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREASISYIKQLLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVCPDMNPVKINELAIQKRLTIHGKEDE
ISPYDYVLQVSGRVEYVFGDHPLIQFQHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGL
FHGTELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKST
KTINPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMG
TVQTNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLVV
LKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQI
WPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELAQYLLQLVQVLKYEPFLDCALS
RFLLERALANRRIGQFLFWHLRSEVHIPAISVQFGVILEAYCRGSVGHMKVLSKQVEALN
KLKTLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCK
YMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRML
PYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRA
IEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVP
FILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTS
VKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3B4ZBF9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola lalandi dorsalis|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TLPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRVTEEKMQRVQKMTFAEWMQACFSPQLEPA
AGTAITDGVNDRSPDLKVTIHFDQSQDSASLKVPSSCTPTELMELAVRKWLTTHGPEEEA
WRGQYVLRLSQCLEFLFGDHPLIQYKYIRTCIQAKESPHLTLVHTSTVKAMFDREMSTIG
AVVSRKSSNPPLPLPPKRRVPTTCVWDVSCPFKIVLVNASKVNAEETAKVQVRAGLFHGT
ELLCKPAVSSESSGRSDHTWKESMLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNP
HINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDINLHCWSSFPDELEEMLNPIGTIQ
TNPYTENATALYIHFPEYSSHPVIFPPFDKILEKAAEIARASDCATMGRGGKKFHIELKE
IMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPK
LSPRDALELLDFNYPDQYVREYAVRCLRDMSNEELSQYLLQLVQVLRYEPYYDCALTHFL
LERAQGNRKIGHFLFWHLRSEIHMPAVSIQFALILEAYCRGSIPHIEVLKKQVEALSKLK
SVNELIKLGTTKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPNVLLSGINVE
RCRYMDSKMKPLWIVYNNKLMGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEASLDL
RIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDAL
ERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRE
RVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPE
LTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7L2F306|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Quiscalus mexicanus|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A665UA80|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
AATMSPGKYGMQEDWEKDGVQEIMMDFLLPTGILLNFPVSRNDTIKNIKRMVWKNARSEA
LFNALGDSDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQI
SLLIGKGLHEFEAQKNHEVNEFRSKMRTFCEEKAQERQQLSWQQWMEYSFPCDLEPCCFP
CGSAKSKNTKKIFININFMLQQDPQDLPEALIRNALKKKATVFRSVRQEPGDYTLRCNGT
WEFIYGNHPLCQFKVSSHKTPSLVKCPTFTDQYDQQHMYNKNPPQPTNAPLSFSCFLIAK
QLNLVKLVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQRLEFDINVADLPRMSRLCFAL
YAVIEKTKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLN
PMGTVEKNPNVDSAAGLLIHFPNIRQYPLYYPPLDKEEVRLPTGKRKDSCLLLLEIMDNK
NYTEFFEDEKELLWKLRADVREYYPESLSKLLLITKWNKREDVVQMVSLLRNWPDLPVIQ
ALELLDYSFPDPAVRSFTVRCLRKLSDDEILQYLIQLVQVLKYESYLDCDLTTFLLERAL
SNRRIGHFLFWHLRSETHVASVSLRFGLILEAYCRGNIHHIKLLAKQNEALGKMKALSDF
VKSGSQKMTAEDLKLCIRQESYLEALSDLLSPLNPSIILEEICADKCRFMDSKMRPIWLM
YKNQWAQGDMMGIIFKNGDDLRQDMLTLQMIQLMETLWKKEGLDLRMIPYGCLSTGNKMG
LIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEEKLDQAIEEFTLSCAGYC
VATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQ
QGRTSNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLA
LGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A7L1EMS9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oenanthe oenanthe|TrEMBL
MELRDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRT
GDYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVSKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQEAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A093I9K9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fulmarus glacialis|TrEMBL
SRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPLAKGL
GTGPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVEKPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGRTPHLTMVHSSTIIAMRDEQTNCIASPPK
MAAKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQGLSGLSKSSGLRLSPVYALSCDSHEQKLQLKEILERRSHTELYEHEKD
LVWKMRYDIRDQYPQALAKLLIITKWNKREDVAQMISLLQTWPELPVLNALELLDFSFPD
CYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFW
HLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKP
QTKEMMHMCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETG
GVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSD
TIANIQLNKSNMVATAAFNKDGEILVFKVKFSFNLFLTLFRDALEQAIEEFTLSCAGYCV
ATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQ
GKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLAL
GKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNR
>A0A6A1Q158|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balaenoptera physalus|TrEMBL
VAEGMELESHEQHVVLREDNRRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRNTKTPET
ALLHVAGHGNVEQMKAQVWLRALETSVAADFYHRLSPDHFLLLYQKKGQWYEIYDKYQVV
QTLDCLRYWKVLHRSPGQIHVVQRLAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFT
RRRLVTPRMAEVASRDPKLYAMHPWVTSKPLPEYLLKKITNNYIFIVIHRSTTSQTIKVS
ADDTPGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQC
LKNGEEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWD
CDRKFRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEF
SIKIKDLPKGALLNLQIYCGKAPALSGKASAEAPAPESRGKAQLLYYVNLLLIDHRFLLR
HGEYVLHMWQLSGKAEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTP
DPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSV
KWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDV
LHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVI
LEAYLRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLEILQN
LNLPQSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGD
DLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTV
GNTGAFKDEVLNHWLKEKYPIEEKAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETG
NLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQVIGLPLDH
LLGTSTRWCLQPSPVTSL
>A0A3Q4BSC3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mola mola|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSTELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVSGSNPNKETPCLELEFDHF
SCPVKYPDMTIIEDHANWNISRELGFNYCHTGLSNRLARDNPMTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHDCVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDXXXXXXXXXXXXXH
FFFWHLKSEMHSKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLKQEKKD
EAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRYFSLPLCSQIAGVRASLLDM
MSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLI
EVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRSCAGYCVAT
FILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGT
QECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLAL
DKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8D0HU02|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphenodon punctatus|TrEMBL
MPPGIYCPVEFWSNEENQNIQVDFLLPTGIYLSLPISCNASLGTIKQVLWHHAQQEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMRQFCEEKAAKRQQLSWAAWMQYNFPLQLEPSSKGLRS
GSLHVPNKNIFVNVKFESGGESFTFQISPKEYPIMLMSYAIKKQATVFRHQTVESPEDYT
LQVNGKCEYLYGDYPLFQFQYIRSCLHLGLMPHLTMVHSSSILAMRDEQTNCIAHPPKVA
PKPPPIPKKKLTTATLWSLEQPYYIHLVQGSKVNADERMKLVVQAGLYHGNEMLCKMVSS
SEVNMCSEPVWKQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKGGESCLHMWSSFPDEKGELLNPMGTVRSNPNTESAAALVICFPSVTS
YPVYYPSFEHLMELGRSGDYARPMAEDPEEKQQLKEILERRTHTELYEHEKDLVWKMRYQ
ICDQYPEALAKLLIITKWNKHEDVAQMIHLLQCWPELPVLSALELLDFSFPERYVGSFTI
NSLKKLTNGELFQYLLQLVQVLKYESYLNCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSNHHMKVLMKQGEALNKMKALNDIIKASSLKNPKPQTKEFMHT
CMRQETYLEALSNLQSPLNPSIILAKVCVDQCTFMDSKMKPLWIVFDNDESGGTGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGAALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCERAYMILRRHGLLYLHLFSLMRAAGLPELSCSKDIQYLKDSLALGKTDEEARKHFQLK
FNEALRESWKTKVNWLAHNVSKDNRQNSLDI
>A0A8C5CH73|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MVPKPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLANIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDEARRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFELVKDPEVQDFRRSILSVCREAMEEREAGGAPSLALYVYPPNVESSPELPQH
IYYKLDKGRLMVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKTRSMHLSAQQLR
LCVLEYQGQYILKVCLLCHALVRVKQPISCQRQALSCTATGKQANQLPASGFCMPCYSPS
ALAPSPCPGGDPTSPPRSLWAFNNLLRVRLLCATYVNVNIRDIDKIYVRTGIYHGGEPLC
DNVNTQRVPCSNPRWNEWLSYDIYMADIPRSARLCLSICSVKGRKGAKEEHCPLAWGNVN
LFDYKDTMVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFCWFNQTVVFPD
DQQIEEHANWTISRELGLTYCLSVSAAEVEQLQSLCSKDPLYELSEQEKDFLWRHRHYCV
NIPESLPKLLLSVKWNSRDEVSQMYCLLKDWPLMQPESALELLDCNFPEPVVREFALRCL
LQGLSDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFFWHLKSEMHNKT
VSRRFGLLLEAFCRSCGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQKTQMKFLVEHM
SRPDYMDALQGFISPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFTNNQV
IFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSYTIMQ
IQCKAGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTRSCAGYCVATFILGIGDRHNS
NIMVKDNGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLLVISKGSQECTKTKEFDR
FQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKTQQEALEYF
TKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>H0YZT0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGV
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGRTPHLTMVHSSAIIAMRDEQTNGITSPPKAA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQNPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFIL
TYDFVHVIQQGKTNNNEKFERFRGYCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKD
IQYLKDSLALGKTDEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C2A9U5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGLCHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVA
QSGKSRSVKKILVNVKFEGSEVSEFMLIYHSFMLSGNSFLWYNAIKKSTVFRAAKQEKPE
DYTLQVNGRWEFIYGEYPLCQFKVSLKFTTSSRLHSYSTTLSDSRTHKIFKMLNHFFFSQ
QQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSNEVSVCSEP
VWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKD
QLKTGEFSLSTWPSVPGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKVRG
KKSNVLIVDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVGL
LRKWPELPAIHALELLDYSFPDPHVRSFTIRCLRNLRWALKKKKKKSSRDVCKALDDELF
QYLLQLVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRSEMHVPSVSLRFGLILE
AYCRGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALS
DVVSPLNPSIVLCELCTDKCKFMDSKMKPLWLMYKNKYDHVGIIFKNGDDLRQDMLTLQM
IQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKD
ALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFG
HFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTL
FVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNW
MMHTFAKDNR
>A0A8C1EK68|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFRAYHSCLSSKLITRNCGRAERI
LDSKIGVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLE
TESVENLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIG
TRSDYVLRVSCRLEFLLEMSNYISKYIRDCLLANESPHLTLVHCDVVKAIFEKEICTIGS
VLARKASNPPLPLPPKKRTPTQLHTCVWKVHSLFRINLVKGNKVNAEDAAKVNINTSELR
IITNLTLTFICLLVAHNQYYIKMNTYRLKKQRSTKNTHLNKYQTIRKAGKVHYPIAWVNT
MVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPV
VFPAFDKGRWGDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQA
LLQIWPKLSPRDALELLDFNYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYD
CALSRFLLERAQSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQV
EALSKLKAVNELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSNLHSPLNPNILLAGV
HVERCKYMDSKMKPLWIVYHNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEAN
LDLR
>A0A3P8U612|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amphiprion percula|TrEMBL
MPPGKYGMQEEWEKEDQQITMDFLLPTGIFLKFPVSRNDTIKSIKKMVWKNARSEALYSA
LGDPDGYVFTCINQTAEREELEEESRRLSDVRPFMCVLKLVAREGDRVEKLTNTQISQLI
GKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERESLPWQQWMEFSFPCELEPCCAPPESS
SVKPKNSKKIFIQIKFESCQESFMLQQDPQDLPVALMKSALKKKATVFRSVRQEPEDYTL
QVNGRWEFIYGKHPLCQFKYIFSCLRNGQNPHLTMIHHSTIVKYQEEQSKVCSQVSKSGS
LSRPPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
TSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNIDSAAGLLIRFPNIR
PHPLYYPPLDKISDMEKNGDAVYATKDEYTKLKEIIDNKNSTEFFEDEKELLWKLRTEVR
DRYPESLSKLLLITKWNKREDVVQMVSLLRHWPDLPAISALELLDYSFPDPAVRSFTIRC
LKKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVAS
VSLRFGLILEAYCRGDIHHIKLLTKQNEALGKMKALSDIVKSGSQKMTVDDLKLCIRQES
YLDALSDLYSPLNPSIFLADICVEKCRFMDSKMKPLWLMYLNPSLQGDMMGIIFKNGDDL
RQDMLTLQMIQLMENLWKTEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNS
AATAAFNKDALLNWLKSKNPE
>A0A7L2E7Q8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anthoscopus minutus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSSKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPILPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNFQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRT
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAVSIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIITTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPGSFRVPYDPGLRAGALVV
>A0A670J2X3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podarcis muralis|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCLPNGMIVTLECLREATLLGIKHDLFKEARKYPLFH
LLQEESSYIFVGVTQEAEREEFFDESRRLCDLRLFQPILKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDPEVQEFRRNILSVCREAVETRGSAGPPSQALYVYPPNVESSPELPKH
VYSKLDKGRIIVTIWVIVSPNNDKQKYTLKTPHDALPEQVIAEAIRKKTRSMHLSPEQLR
LCVQEYQGKYLLKVCGCDEYLLEKYPLSQYKYMRNCITIGRLPHLMLMSKESLYSQLPAN
VFVLPSYARRSATSSHVNGDVPTKSLWSINSLLRIKILCATYVNVNIRDIDKIYVRTGIF
HGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDLPRAARLCVSICSVKGRKGAKEEHCP
LAWGNVNLFDYKDTLVAGKMALNLWPVPHGLEDLLNPIGVGGSNPNKETPCLELEFTWYS
HTVKFADATEIEEHANWAMSRELGLNYCMVGLSNRLARDSSLDESELEQLRSICNRDPLS
EITEQEKDFLWRHRHYCVNIPETLPKLLLSVKWNSRDEVAQMYCLLREWPLIKPELSMEL
LDCNFPDPVVREFALKCLVKGLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLTMKALTNQ
RIGHFYFWHLKSEMHSKPVSQRFGLMLEAFCRGCGMYLKHLNRQVEAMEKLINLTDILKQ
EKKDETQKMQMKFLVEQMRRPDYMEALQGFICPLNPVHQLGNLRLDECRIMSSAKRPLWL
NWENPDIMSELLFTNHEIIFKNGDDLRQDMLTLQIIRIMESMWQNQGLDLRMLPYGCLSI
GDCVGLIEVVKSSHTIMQIQCKGGLKGALQFNSNALHHWLKDKNKGEGYDAAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQVSGFLYSLRETKLQGTRQKAFSVVAPALRNALP
ADVKEKNNYQTLRRHLKAALFREAFNV
>A0A8C6PMI8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius furzeri|TrEMBL
MPPGKYGMQEEWEKEGDQNILMDFLLPTGIFLKFPVPRNDTIKNIKKMVWRNAKTEALYC
GLGDPEGYVFTCINDTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNSHISSL
IGKGLHEFEAQKNHEVDEFRSKMRTFCEEKALERHNLPWQQWMEYSFPCDLEPCCSPPVH
GGTKSKHTKKLFINVKFEACDESFMLQQDPLDIPVALMKSALKKRATVFRSVRQEPEDYT
LQVSGRWEFIYGNHPLRQFKSRPPPLPMKKQNTSSLWSINEPFYIHLLQGSRVNADEGMK
LVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQKLDFDINVSDLPRMSRLCFALYAVIEK
TKKPRGTKKKNKRADCPIAWVNTMVFDYKDQLKTGEFILSTWPSVPDDKSDLLNPMGTVE
KNPNVDSAAGLLIRFPNIRPHPLYYPPLDKVIPPENLLISMIVMERNGDAVFATKVEVRP
CHCTIFFILFYYIIGNRMRLKEIMDNKNSTEFFEDEKELLWKLRTEVRDCYPESLSKLLL
ITKWSKREDVVQLPSWDAAPMVSLLRNWPDLPAIQALELLDYSFPDPAVRSFTIRCLRKL
SDNELLQYLIQLVQVLKYESYLDCDLTTFLLERLTAEETSTTSSCQKMTVEDLKLCIRQE
SYMEALSNLMSPLNPSIILVELCADKCRFMDSKMKPLWMMYKNPSEHADMVGIIFKNGDD
LRQDMLTLQMIHLMEDLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKHSDTIANIQRNNSN
SAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEWA
YKILCKNGTLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEDEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A1A8VGB4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius furzeri|TrEMBL
MPPAMTDLLDIWASHSPLAGHALEKITVDFLLPTGIYIQMDVPRDATIQHIKLLLWKQAQ
NFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRCKMFRITEEKMQQAQVMTCTEWLQACCSPQLEPT
AVTLVTDGVNDRPADLKVFIHFDQSQDSTSLKVPVSCTPSELMEIAVKKWLTTHAPEDEA
YSRQYVLRVSQCLEFLCGDHPLIQYKYIRNCLQAKESPHLTLVHTSTVKIMFDKEMSAIG
AVVSRKSSNPPLPLPPKRRPPTQVQTSVWNVSKPFRIDLLKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSDSSGRSEHTWKNNTLKFELSVSDLPRMTRLCFAIYAVTDKVKKQKST
KNAHSSKYQTIRKAGKVLYPIAWVNTMVFDYRGQLKTGDVILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHPVIFPPFDKILEKAAQLVGVIEQPIGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVSCLHDMSDEELLQYLLQLVQVLRYEPYYDCPLTH
FLLERAQRNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSEALSDLTSPLNPSVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLMSGDALGIIFKNGDDLRQDMLTLQILRLMDLLWKESNL
DLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQEGKTGNTEKFGSFRKYCEEAYLILRRNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKNDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A1A8AB05|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius furzeri|TrEMBL
MPPAMTDLLDIWASHSPLAGHALEKITVDFLLPTGIYIQMDVPRDATIQHIKLLLWKQAQ
NFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRCKMFRITEEKMQQAQVMTCTEWLQACCSPQLEPT
AVTLVTDGVNDRPADLKVFIHFDQSQDSTSLKVPMSCTPSELMEIAVKKWLTTHAPEDEA
YSRQYVLRVSQCLEFLCGDHPLIQYKYIRNCLQAKESPHLTLVHTSTVKIMFDKEMSAIG
AVVSRKSSNPPLPLPPKRRPPTQVQTSVWNVSKPFRIDLLKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSDSSGRSEHTWKNNTLKFELSVSDLPRMTRLCFAIYAVTDKVKKQKST
KNAHSSKYQTIRKAGKVLYPIAWVNTMVFDYRGQLKTGDVILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHPVIFPPFDKILEKAAQLVGVIEQPIGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVSCLHDMSDEELLQYLLQLVQVLRYEPYYDCPLTH
FLLERAQRNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSEALSDLTSPLNPSVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLMSGDALGIIFKNGDDLRQDMLTLQILRLMDLLWKESNL
DLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQEGKTGNTEKFGSFRKYCEEAYLILRRNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKNDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A485P1Q3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lynx pardinus|TrEMBL
MPPFHCLARPIRVDIHKVPAIALQVAQGMELDNYEQPVVLREDNRRRRRRMKPRSTTASL
SSMELIPIEFVLPTSQRNSKTPETALLHVAGHGNVEQMKAQVWLRALETSVATDFYRRLG
PDHFLLLYQKKGQWYEIYDKYQVVQTLDCLRYWQVLHRSPGQIHVVQRRAPSDETLAFXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRRRLVTPRMVEVAGRDP
KLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDTPGAILQSFFTKMA
KKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNGEEIHLVLDTPPDP
ALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGIDIPVL
PRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPRGALLNLQI
YCSKVPVLAGKTSAETPSSESKGKTQLLYYVNLLLIDHRFLLRHGEYVLHMWQISGKGED
QGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPNQLRK
QLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLAR
REVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYH
DSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFT
DQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLPKSFRVPYDPGLKA
GALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMES
IWETESLDLCLLPYGCISTGDKIGMIEIVKEATTIAKIQQSTVGNTGAFKDEVLNHWLKE
KCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYK
SFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSM
MLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLG
IKQGEKHSA
>A0A2K6SKI4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Saimiri boliviensis boliviensis|TrEMBL
MCFGFIMPPAMADILDIWAVDSQIASDGTIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDGLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
ISPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVVNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIIYHVWENNNPFQIILVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEVSGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKAKTKKSTKAI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A4X2KVY0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vombatus ursinus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVHAPHSRALYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASTKSLWGVNSALRIRILCATYVNVNIRDIDKIYVRTGI
CHGGEPLCDNVNTQRVPCSNPRWNEWLMYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMSVIEEHANWTVSRELGFNYSHAGLSNRIARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>G0R493|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ichthyophthirius multifiliis (strain G5)|TrEMBL
MLQNQKQCQFKLSNNQFLQELVDIQFKIEKNLICVDPDSHQIYSLNQETNEFYIQLNVDN
DYRQRAETAISEIEQITNLNKGNWIIDHEKAEQYRRRKIPNYLLQRTDWNHPTYICQSPL
SQAFVQKKQITLLVNLSEFIDKLKKSNKYQEKIQVGNQGQQQPKKQKQEGKIQYLKIDVG
LVTAADEVMKIIIRQIYQEYDIKLTPSPNHTFILKISGYREFLNGHYPMLSYDRVRTHLR
ADTPMKVLLLEKPNGDQKQKLFPPQIEKILISIVQKFKDKKISHDYSIEDILEFVQKKSQ
DVKQIFKDGFNFKIIDNATKKTYEEYNVNWEKLRNIPLLLWFKQYIYYINDFYIQKILYK
IQMHKQNVLKVVYTILYVFYLIIQFYIFKKGQKMAKLFFGEGHPTELRLRVIHKERMKEF
VEKRRNLFYQGVFSEKPTNLYSGECDCQFKIKIKGIENLYRLLQQTDHNSNQSETRASYN
GILPPNYITKKGECQKYIIYLNYIQLYIFIYYIQIYFYILNYLQINKQIQDHGHKKSLYF
KKLADLFDLNFPPYLIQIQVKIIYGNRQLAIKKETLKIPFSNTPRWNEWIKFRSLKISQL
PLEARLCFDIIIYSCSGQESQVYIHILFFINKNKIIASTTINIFDQHCKFMQGINSLNLW
PFYANEDRLACMGQYWGIIDPSLKPDPSDFDKWQQFKAYEFSRLFVEFDTFSKHMYWSLR
DDKSMIQLGQLQYFINFILFEKKGFQPSKNRLEDLWQYTPQNQYLADLKDLLKRDPLDRQ
FDMRQKLILLICRNHFKSIPDALDTFLCAVDWSNPEHIRETYNLIKQWKPPPAEECITFL
DVHHADELIRLFGVERLSKMADDELKLYMIELIQGLMFETYHYSPLQELLLERSLLNPFV
VGHELFWGLKSQLHLKPSFERFALVLEQLLMVCGEYRNELLKEVQVNDEVKQVAKKIKAK
KCQNANERIENTQQLLQELKFLRTEDQGIRFYICYRQQIIIKKFRTQKMQSHELEKLPLW
LVMQNMEQGQEEFMIMFKDGDDLRQDLLTLQLIRIMDKIWLDAGQDLRMKPYNVISTQDQ
VGMLEIVLKSETTAKIHTELGQFGAFKKETILLYLRKNSVDENQKFDQKKFETNRENFIN
SCAGYCVATYVLGIGDRHSDNIMITKEGHLFHIDFGHFLGNFKKNFGFNRERCPFVFTPD
MEYVLTYDKKDGQNFYEKFEQKCCDAYNLIRKHGHFLINIFRMMLSAGMPELQKQSDIQY
LVDMLNLNLSEQEASQHFKNELIRSKNSYFRQVDNFIHEYVRK
>A0A091RZL7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mesitornis unicolor|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMSVIEEHANWTISRELGFNYSCAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLR
>A0A6P7MXU5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Betta splendens|TrEMBL
MPPGKYGMPGEWEKEGDHEIMMDFLLPTGIFLTFPVSRNDTIKTIKKMVWKNARGEALFA
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMFVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEVKAQERQALPWQQWMEYRFPCDLEPCCSPQQC
GKSKGTKKILVNVKFEASDESFMLQQDPQDLPVALVKSALKKKATVFRSVRQEPEDYTLQ
VNGRWEFIYGKHPLCQFKYIFACLRNGQNPHLVMVHHSTIRKHQEEQGRMCNQAYKSCSL
SRPPPLPLKKQNTSSLWSINEPFCIHLMQGSRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVCCEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEVLLSTWPSVPDDKSDLLNPMGTVERNPNVDSAAGLLIRFAHVRP
YPLYYPPLDKMSDTERNGDASFATNEEYSKLKEIMDNKNYTEFFEDEKELLWKLRCEVRS
RYPESLSKLLLITKWNKREDVVQMVSLLRNWPVLPAIHALELLDYSFPDPAVRSFTIRCL
RNLSDDELLQYLIQLVQVLKYESYLDCDLTMFLLERALSNRKIGHFLFWHLRSEIHVASV
SLRFGLILEAYCRGNIHHIKFLTKQNEALGKMKSLSDFVKSGSQKMTVEDLKLCIKQESY
LEALSDLLSPLNPSIVLSEICADKCRFMDSKMKPLWLMYRNPGSQGNMVGIIFKNGDDLR
QDMLTLQMIQLMENLWKREGLDLRMSPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSA
ATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCELAYK
ILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLSLGKSEEEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDNRP
>A0A850YHU8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aegithalos caudatus|TrEMBL
MPPGIYCPTDFWSKGENQNIHVDFLLPTGIYLNLSVPCNASLGTIKQVLWQQAQHEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGRGLHEFDSVQDPEVSDFRTKMCQFCEEKAARRQQLSWAAWMEYNFPLQLEPVAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETLQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKAA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
WEVAVCSEPVWRQRLDFDISICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAAEDSEEKLQLREILECRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGSGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A4W3JP03|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPAMTDPLDIWAVDSQIPADNSITVDFLLPTGIYIQLDVPREATIDQIKMLLWRQAQTY
PLYTVLGEKDSYMFQCVNQSAVHEELEDESRRLCDVRPFLPVLKLVARNCNRSERLLDSK
IGVLIGKGLHEFDALTDPEVREFRSKMRMFNEEKMLKLQGLSWMDWLKHSFPPELESTAF
NNFEDKLPKENLVVAVQFDSCQENFSFQISPNLNPLDLNELAIRKQLTIHGKENEEFNPR
DFVLRVSGKQEYLFGEQPLIQFRYIRNCVLKGSNPQLTLVDCCTIKEMCDREMSAIGVAL
HRKISNAPLPLPPKRRTISQMATNVWDINSPFKMLLIRGNKINADEAVRVQVRAGIFHGT
ELLSKSVVSTEVSGKNDLVWNEILDFEINLCDLPRMSRLCFAVYGVMDKVKKQKSTKNAS
KYQTIRKAGKVHYPIAWVNTMVFDFRAQLKSGDLDLHCWSSFPDEMEDMLNPMGTVQTNP
YSENAASLHIQFQEYSKSVIYYPAFDKILEKAAEIARSNDTLSMSGRGGKKLHIELKEIM
ERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDVAQLQALLQIWIKLC
PRDALELLDFNYPDQYVREYAVKCLKEMRILSNTGKHFNSKSNRAFDEELSQYLLQLVQV
LKYEPYFDCALSRFLLERAQANRRIGHFLFWHLRSEMHLPATSLQFGLILESYCRGSFTH
IKELSKQMEALSKLKAINNLVKLSYLKVTRTKVKEVMNTCLKQPVYTEALSDLQSPLNPS
VILSKLNVDKCKFMDSKMKPLWILYNNKMSGGEPVGIIFKNGDDLRQDMLALQILRLMDM
LWKEAGLDLRIVPYGCLATGDKSGLIEVVSASETIANIQLTNSNVAATAAFNKDALLNWL
KEKNTGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRETGQLFHIDFGHILGNF
KSKFGIKRERVPFILTHDFIHVIQQGKPGNAEKFGRFRQCCEEAYLILRKNGNLFITLFA
LMLTAGLPELSSVKDIQYLKDSLALGKSDDEALKQFRQKFDEALRESWTTKVNWMAHIVA
KDNRS
>A0A674K421|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Terrapene carolina triunguis|TrEMBL
ICIMGVMPPYRAGVLQGDVMVQPAHRWFHPAVGLSQVVWRHAQYEPLYHMLNDPEAYVFT
CINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHEFDSV
RDPEVNDFRAKMRQFCEEKAAKRQQLSWMAWMEYNFPLQLEPLAKGPRTGPLRVPNKNIF
VNVNFTFQVSPKEFPVMLMSYAIKKQATVFRHQTVESPEDYTLQVKGKCEYLYGNYPLYQ
FQVSLFPPPTGELFPKRTGTFLSGRQEKDAPCYCRPCSLCRPTHESLWSLNQPFYIELVQ
GSKVNADERMKLVVQAGLYHGNEMLCKMVSSAEVNVCSEPVWKQRLDFDISICDLPRMAR
LCFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEK
GELLNPMGTVQSNPNTESAAALVICFPSVLLHPVYYPSFEQVKGRHLSADRFTNFASCGG
KGALPQLREILERRSHTELYEHEKDLVWKMRFEIRDQYPEALAKLLIITKWNKHEDVAQM
ISLLQSWPELPVLNALELLDFSFPDRYVGSFTINSLKKLTDDELFQYLLQLVQVLKYESY
LDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSNYHMKVLMK
QGEALNKMKALNDFIKVSSQKATKPQAKEMMHVCMKQETYLEALSNLQCPLNPTVILAEV
CVDHCTFMDSKMKPLWIVFNNEEAGGRGVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEG
LDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPG
EALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGI
NRERVPFILTYDFVHVIQQGKTNNSEKFERFRDYCEKAYMILRCHGLLFLHLFALMKAAG
LPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8D2L844|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Varanus komodoensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEKEEFFDETRRLCDLRLFQPFLKVIEPEGNRDEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVELRDVNAPHSRALYVCPPNIESSSELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMAKESLYAQLPKD
TFAMPSYSRRISTATPYMNGEASAKSLWVINSHLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLQYEMHVLDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDCF
SSPVKFPDMSVIEEYANRTTPRDQGFNYSHAGLSNRLTRDNELRESDREQLRAICTRDPL
SEITEQEKDFLWSHRQRCRNIPEILPKLLLAVKWNSRDEVAQMYCLIKEWPYIKHEQAME
LLDCNYPDPMVRAFAIRCLEEDLTDDQLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQIQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDPAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C6UX04|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neogobius melanostomus|TrEMBL
CINQLFSVSRQLLWKQAQSFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFL
PVLKLITRNCGRAERLLDSKIGVLIGKGLHELDAINDQEVKDFRGKTLRQSEEKMQKVQM
MSCTEWLQASFSQQLEPGPGPDQINGVSDRSTDLKVTIHFDQSQDSASLKVPLSCTPPEL
MDMAVRKWLTTHGPEKEASRGQYFLRVSHSLEFLCGDDPLSHYKYIRTCVQTKEPPHLTL
VHSSIIQEIRKSLPLPLPPKRRTPTVSPEKLSVQVRAGLFHGESSGRSEHTWRDSTLEFE
ISVCDLPRMTRLCIAIYAVMDKVKKQKSTKNTHINKYQTIRKSGKVLYPIAWVNTMVFDY
KGQLKTGDIILHCWSSFPDELEEMLNPIGTVQTNPYTENATALHISFPEYLPHAIVFPPF
DKILEKAAQIARASDCSPMGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCREN
FPQSLPKLLLSVKWSKHEDMAQLQVLLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLR
DMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQRNRKIGHFLFWHLRSELHMPAVS
VQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKFGTMKNARSKAKEAMLTKEAM
MTCLRQSGYYETLSDIHSPLNPNILLAEVNVERCRYMDSKMKPLWIVYNNKLLDGDTLGI
IFKYGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIAN
IQLTSSNVAAAAAFNKDALLNWLKERNSGDALDHAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFASF
RQYCEEAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFR
QKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C5TQU2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Malurus cyaneus samueli|TrEMBL
MYSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQ
AHSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKL
DSKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEP
VIPESIQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEV
DPADYVLQVSGRLEYVFGDHPLIQFQYIRTCVMNRTLPQLTLVECCTIKKMCEQEMIAIE
AAINRKSSNLPLPLPPKKTRSVWDICNPFKIVLLKGNKLNTEENAKVHVRAGLFHGTELL
CKTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNTSK
YQTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPY
TENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIME
RDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLP
REALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLER
ALGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLN
SLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKM
KPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLA
TGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTL
SCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYD
FIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C3QBC5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geospiza parvula|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVNEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPTKNIFVNIRFQSGGESFMFQISPREFPITLMSYAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPNYGSLWSLEQPFYVELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKVRGRAHTRG
>A0A4W4F703|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MGPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELLKDPEVQDFRRGILSVCREAMEEREGGGAHTQALYVYPPSVESNPQLPQH
IYCKLDKGRLIVTIWVVVSPSNSKQKYTLKMAHDCLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVSCRRNHEKILHDQENEYTKRREWGLILSLVEHQWRVTRFGCGSSPC
HXXXXXXXXXXIGSSGHVVGLLEVRS
>A0A4W4EXR1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MFRVPWFGCGVLSAMPPAMTDLLDLWVEPGLDGDDQVTVDFLLPTGVYIKMDVPRQSSLQ
CIKQMLWKQAQGYPLFTLLGEMDSHIFECVNQAAVHEELEDESRRLCDVRPFLPVLRLIA
RNCGRAERLLDSKIGVLIGKGLHELDALQDQEVKDFRSKMQRISEENMQCVHMMSWGEWL
QSCFSPQIEAGPVNGYCDGSEGEVKIIMHYSESQDTASLKVPLSCTVAELMEQALRKWLT
THGSEEDEGCLGDYVLRVSAKLEFLFGDHPLHHYRYIRSCLLAQEVPHLTLVHCSVVKAM
FEREICTIGGVLAWKASNLPLPLPPKKRGLTQVHTCVWEVHSQFKITLVKGIKVNAEETA
KVQVRAGLFHGTELLGKVAVSSESSGRSEHVWNKALEFDLSICDIPRMSRLCFAIYAVMD
KVKKQKSTKSVQMNKHQTIRKSGKLLYPIAWVNTMVFDYRGQMKTGDITLHTWSSFPDEL
EEMLNPIGTIQTNPYRENATALHIRFPEYSPQPVVFPPFDKILEKAAEIAGASDTLSMGR
GGKKFYVELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMA
QLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVNCLQDMSDEELSQYLLQLVQVLRYE
PYYDCALTRFLLRRAQANRKIGHFLFWHLRSEMHMPAVCVQFALILEAYCRCSVPHIEVL
KKQVEALSKLKAVNELIKLGTIKTKKMKEAQLKDAMMKCLRQTGFIETLSDLHSPLDPQV
LLAGVNVERCRYMDSKMKPLWIVYNNKLLVGDTMGIIFKNGDDLRQDMLTLQILRLMDIL
WKEANLDLRIVPYGCLATGDRTGLIEVVSYSETIANIQKNSSNMAAAAAFNKDALLNWLK
DKNPGDALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFK
SKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRQNCEDAYLILRKNGNLFITLFAL
MLTAGLPELTSVKDIQYLKDSLALGKTDEDALKQFRQKFDEALRESWTTKVNWMAHNVAH
PS
>A0A4W4HH02|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGRN
ASNMGRLLFFKILNEFGMQRMGHFLFNKQVLELRIHLPHCTELSFSRRESGSEIPASGII
IIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLKMCVQEYQGK
YILKVCGCDEYLLEKHPISQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPADTFTMPSYSR
RISTATPYMNGEASSKSLWAINSTLRIRVLCATYVNVNIRDIDKIYVRTGIYHGGEQLCD
NVNTQRVPCSNPRWNEWLTYDMYIPDVPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNL
FDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYFSSPVKFPDM
ATVEDHANWMISREMGYSYCQSGPSSRLARDHIITEADIEQLRQLANRDPLSEITEQEKD
FLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDP
MIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTNQRIGHFFFW
HLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQK
VQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIM
SELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIE
VVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGETDDMAIDLFTRSCAGYCVATF
ILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGT
QECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLAL
DKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A2D0RUY0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ictalurus punctatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKFPLHH
LLQEEASYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESSPELPKH
IFGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMD
TFTMPSYSRRISTATPYMNGEASSKSLWTINSNLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLMYDMYIHDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SCPVKFPDMTTIEDHANKIMSREMGYNYFQSGQSSRQARDHHIMEGDIEQLRQVANRDPL
SEITEQEKDFLWRHRQYCKNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIREFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLGRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGETYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A6P8SV61|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gymnodraco acuticeps|TrEMBL
MPPAMTDLLDIWAAHSPLAGHALDHISVDFLLPTGIYIQLDVPREATIQHIKLLLWKQAQ
SFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAETLLD
SKIGVLIGKGLHELDAMNDQEVKDFRSKMFRLSEERMQQVQMMSCNEWLQACFSPQLEPP
AGAAAIAEPVDLKIIIHLDQSQDSASLKVSSSCTPPELIELAVRKWLTTHGPEEEAWRGQ
HVLRVSHCLEFLCGQQPLIQYKYIRTCMQAKESPHLTLVHSSTIKVMFDKEICAIGAVVS
RKSSNPPLPLPPKRRVPTQVQTCVWDVATPFKIVLVNGSKVNAEETAKVQVRAGLFHGTE
LLCKPAVSSESSGRSDHTWKDSTLEFDLSVCDLPRMTRLCFAIYAVMDKVKKQKSTKNSH
SNKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQT
NPYTENATALHIHFPEYSSHSIIFPPFDKILEKAAEIAGASDSVPMGRGGKKFHIELKEI
MERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKL
SPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLL
QRAQGNRKIGHFLFWHLRSEIHMPAVCVQFALMLEAYCRGSIPHIEVLKKQVEALSKLKS
VNELIKLGTLKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNILLSGINVER
CRYMDSKMKPLWIVYNNKLMGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLR
IVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNTGDALE
RAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRER
VPFILTHDFIHVIQQGKTGYTEKFASFRKYCEEAYLVLRKNGNLFITLFALMLTAGLPEL
TSVKDIQYLKDSLALGKTDDDALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C8JYQ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRVKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQLSKS
RSLSKPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVV
TSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIHFPNI
RPHPLYYPHFDKVHLILHTRFNIDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKLLLI
TKWNKHEDVAQMVTFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYL
LQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYC
RGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLL
SPLNPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDTVGIIFKNGDDLRQDMLTLQM
IQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKD
ALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFG
HFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTL
FVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNW
MMHSLAKDSRL
>G3V839|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rattus norvegicus|TrEMBL
MCFRSIMPPAMADTLDIWAVDSQIASDGSISVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEDKIQSLVGLSWIDWLKHTYPPEH
EPSVLENLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEEE
ASPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSSLPLPLPPKKTRVISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQ
TNPYAENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASGDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALDNRRIGQFLFWHLRSEVHTPAVSIQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCRYMD
SKMKPLWLVYSNRAFGEDAVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>J3S885|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crotalus adamanteus|TrEMBL
MPPRPSSGELWGMHLMPPKILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVELRDANAPHSRALYVCPPNIESSDLPKHI
YNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLKL
CVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMTKESLYAQLPLDT
FAMPSYSRRISTATPYMNGEASAKSLWAINSHLRIKILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLQYEMLVLDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFS
SPVKFPDMSVIEEHANWIISREQGFNYNHAGLSNRIARDNELRDNDKEQLRAICTRDPLS
EITEQEKDFLWSHRHYCVSMPEILPKLLLSVKWNSRDEVTQMYCLVKDWPQIRPEQAMEL
LDCNYPDPMVRAFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQ
RIGHFFFWHLKSEMHNKNVSQRFGLLLDSYCRACGMYLKHLSRQVEAMEKLINLTDILKQ
EKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLWL
NWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSI
GDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDPAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAY
IRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C2V7B2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chinchilla lanigera|TrEMBL
MELENSEPPVILREDNLRRRRRMKPRSAAASLSSTELLPIEFVLPTSQRHSKDPETVLLH
VAGHGNVEQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHHWKVLHRSPGQIHLVQRRAPSEETLAFQRQLTALMGYDVTDVSNVHDDELESTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPEYLSKKITNNCIFIVIHRSTTSQTIKVSADDT
PAAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGDTPIKNFQWVRHCLKIG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPILPRNTDLTVFVEANIQHGQQVLCQRRTSAKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPGLSESRGKAQLLYYVNLLLIDHRFLLRHGEYVLHMWQISGK
GEDQGSINADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPNQ
LRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGEQETVAKTYQL
LARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFE
PYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGAAMLQ
DLAQQVQVIEMLQKVTIDIKSLSAEKYDVSAQVISQLKQKLENLQNSNLPRSFRVPYDPG
LKAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRI
MESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHW
LKDKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILG
NYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVKAYLALRHHTNLLIIL
FSMMLMTGMPQLTSKEDIDYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHL
VLGIKQGEKHSA
>A0A8C0MJU5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYCFPLQLEPSARSWGP
GTLRVPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMR
QEAYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>U3BJR2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callithrix jacchus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLNGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRTKMCQFCEEAAARRQQLSWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHFSSILAMRDEQSNPAPQVQKPR
SKPPPIPAKKPSSVSLWSLDQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISISDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLHMWPSVPDEKGELLNPTGTVRSNPNSDSAAALLICLPEVAP
YPVYYPPLEKILELGRHSECVRVTEEEQLQLREILERRGCGELYEHEKDLLWKLRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLGALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSSGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C0N9K7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNDFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPNDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKNI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNKAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6P3E769|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ovis aries|TrEMBL
MCFYFIMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISCIKQMLW
KQVTNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPEL
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDQSLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMVAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHVWNESLEFDINTCDLPRMTRLCFAVYAVLDKVKTKKSTKTM
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPHALPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3B3D737|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias melastigma|TrEMBL
MPPRPSSGELWGMHLMPPSIVVDCLLPNGMILSLECLREATLVTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILSREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPSVESSTDLPRH
IYNKLDKGQIIVVIWVIISPSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPSD
NFTMPSYARRISTATSYMNGETSSKNLWTINGMLKIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLSYDMYILEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEQF
SSPVKFPDMAYVEEHANWNISRELGFNYSHTGLSNRLARDNPLTDNDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHSCINIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKEDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>Q3U7H2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|TrEMBL
MPPGVDCPMEFWTKEESQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
ISKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLRVSNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKRATVFRQPLVEQPEEYA
LQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGRITEEEQLQLREILERR
>Q3TBW3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|TrEMBL
MPPGVDCPMEFWTKEESQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLRVSNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYA
LQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGRITEEELQLREILERRGSGELYEHEKDLVWKMRHEVQEH
FPEALARLLLVTKWNKHEDVAQLSQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIK
SLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVP
SVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMC
MRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C4UEI5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Falco tinnunculus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEDHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C4U5K6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Falco tinnunculus|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDESRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAVEAAIN
RKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHIWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFHAVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHAGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A671L3Q2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCFFIAVLPFWLCSKWHKTFSTGHHEFDSQKN
HEVNEFRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQSGKSHSGKKILVNV
KFEGSEETFVLQQDPQDLPMFLKRNALRKKSTVFRPAKQEKPEDYTLQVNGRWEFIYGKY
PLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRTRAQSKPPPLPLKRQN
TSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSNEVSVCSEPVWD
QKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLK
TGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKLNE
LGMNCEKVVATKEEHLKLREIVDNKNYTEFFEDEKELLWKLRKEVRQRYPESLPKLLLIT
KWNKHEDVAQMVCLLRKWQELPAIHALELLDYSFPDPHVRSFTIRCLRNLRNDELFQYLL
QLVQVLKYESYLDCDLTCFLLERALSNKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCR
GSIFLIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVS
PLNPSIVLCELCADKCKFMDSKMKPLWLMYKDKYDHVGIIFKNGDDLRQDMLTLQMIQLM
DVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLN
WLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLG
NFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNL
FALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHS
FAKDNR
>A0A6P3HK07|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bison bison bison|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASMSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGNHQHEPGK
>A0A7L3XWI9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calonectris borealis|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGRTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEERLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKREDVAQMISLLQTWPELPVLNALELLDFSFPDCYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P6JYY3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carassius auratus|TrEMBL
MEHQASDDEPPVVRREENKRRRRKMKAFTSASAVSTDQIAVEFVLPTSDKNSKDSDTLHL
DVTGNWTVEQLKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVVRTQPSEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDPKLYSTDPWITSKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQNFFNKITKKRALLGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKN
GEEIHLVLEPPLDPEQDVVQKEEWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSEMIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKESSMAVAILLDKYCYPVALPKSKDSPDSEMEGERG
QREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEA
VAITHCLLERSTMWDRSSLDVGLALQLLDCHFSDENVRTLAVRKLETLEDDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRG
CGEAMLQDLRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQMRQKLECLQTSGLPDSF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSHDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLREKCVNEEKFQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFLGISKERVPFVLTPDFLYVMCTTGKKSSPNFLQFQNVCLKAYLALRHH
TNLLIILFSMMLMTGMPQLSSKEDIEYIREALTVGQSEDEAKQHFLDQIEICRDKGWTVQ
FNWFLHLVLGIKQGVEKRST
>A0A3B4ZA38|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Stegastes partitus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFAMPSYARRISTATPYMNGETATKSLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWIISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVGNRDPL
SEITEQEKDFLWRHRHDCANMPEILPKILLAVKWNSRDEVSQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A2K5R105|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cebus imitator|TrEMBL
MCFGFIMPPAMADILDIWAVDSQIASDGTIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDGLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
ISPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIIYHVWENNNPFQIILVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEVSGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKAKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRTKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A2K5QXM4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cebus imitator|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWSEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSISREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A852FBI4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Peucedramus taeniatus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRREGSFPPLAADAYFALLSCF
APGLHEFDSVQDPEVSDFRSKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPVAKGLGTG
SLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYTL
QVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAAC
KPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSSS
EVSVCSEPVWRQRLDFDISICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAWV
NVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAH
PVYYPSFEQLLELGRNGEQPRGAAEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDI
RDLYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAIN
SLKKLTDDDVFQYLLQLVQVLKYESYLDCDLTKFLLERALSNRKIGHFLFWHLRSEMHVP
AVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMC
MKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNQETGGGGVGIIFK
NGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQL
NKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGY
CERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKF
NEALRESWKTKVNWLAHNVSKDNRQ
>A0A803XR34|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Meleagris gallopavo|TrEMBL
MQWNIIWFLSRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVV
WKHAQYEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRV
KKLINSQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPL
QLEPMAKGLGTGLFNGNLSFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYTLQV
NGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQVNSIANPPKMAVKP
PPLPKKKTGQVPVDSWYSYFFSPQLVVQAGLFHGNEMLCKMVSSSEVNVCSEPVWKQRLD
FDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKALGSVHYCTKEDCPIAWVNVMLF
DYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNVASHPVYYP
SFDKAFGLRLSPLYALCCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQ
ALAKLLTITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLT
DHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRF
GLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQETY
LEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLR
QDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMA
ATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETG
QLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYM
ILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRE
SWKTKVNWLAHNVSKDNRQ
>A0A852FIE7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Peucedramus taeniatus|TrEMBL
DSIMPPAMTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQA
HSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESIQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENTKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALGNRRIGQMLFWHLRSEVHIPAVSLQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3P8WMH5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cynoglossus semilaevis|TrEMBL
MDERQVQVSDTEQRVQREETWRRRRKKAISSASSASMEHVTVEFVLPTVARSGGGPDRLL
LDVAGNWTVDQVKAQLWLKAVTSNLCPDFYQRFTPDHCILLYQKKGTMCEIYDKHQVFQT
LDCIRYWRALKKDRGQIQLVPRPQPSEESVRYQSYLNYLIGYDVTDVSDVHDDELEFTRR
KLLTPRRIELSNRDPQLYSLDPWVTRKPLPEHLLSKVSNGHILVVIHISTASQTIKVSID
DTPVLLSFFSKVANKRSLFGLPEDVCEADYVLRVCGREEFLYGDKPLQNFNWIRHCLKNG
EEIHLVLEKPPDPDLDQVQKEDWAQVDDCTGVAGTHEQLTIDAKDHERVFTVSMWDCNRK
FRVKVLGLDIPSLPKLSECMVFIEASIFHGQQLLAQERTSSKTFTEEVLWNCWLEFSIKI
KDLPKGSRLNLQVPIVRRLRAVSVSGEFILHMWKVPEKSEESSSSINADKLTSATNPDKA
SSMAVAVLLDKYCYPVVLPKTRDATPGGEDSESGERGQREMPNHLKKQFEAIVVTDPLHP
LSPEDKELLWHFRHECIRDPRAYPKLLGSVQWGKQEDVLVTHRLLERSSAWDSSVLDVGL
AMQLLDCHYSDAQVRSLAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRCLLKRSK
RIGHFLFWFLRSEIAQSMHYQLRYAVLLEAYLRGCGEAMLQDYRRQVKMTEALQKVTREM
KAMAADKYDVTAQVVFQLRQKLESLQSFGLPDSFRVPYDPGLRAGALLIDQCKVMASKKK
PLWLQFKRADPTTRSKDPIGIIFKDGDDLRQDMLILQILLIMDSIWETESLDLCLLPYGC
ISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFKDEILHQWLRDKCVSEDKFQQAVQRFL
YSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTP
DFLYVMGTAGKKSSPHFQKFQDVCVKAYLTLRHHTNLLIILFSMMLMTGMPQLTSKEDIV
YIREALTVGRNEDEAERHLLDQIEICREKGWMVQINWFVHLVLGIKQGVDKRST
>A0A8C7JHJ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLTNIKQQLFTEARKYPLYP
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFEQLKDPEVQDFRRSILGVCREAMEEREGGGAETQALYVYPPNVESAPRAATT
HLLQTGQGLKYTLKISHDSLPEQLIAEAIRKKTRSMHLSAQQLRLCVQEYQGQYILKVCG
CDEYLLEKYPPQSYIRSCITVGRLPHLMLVSKDSLYSQLPGSGFVAPSYSRRTPQPSPCP
GGGDPSSPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRV
PCSNPRWNEWLSYDIYMTDLPHSARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYKDTL
VCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFSWFNQVVLFPDEQQIEEHA
NWTISRELGYNYSLGLSSRLACDSSVSAADGEQLRSLCSRDPLYELSEQEKDFLWRHRHY
CVNIPESLPKLLLSVKWNSRDEWSQVWLSVKCPGAVDCNFPDPMVREFALRCLVQGLTDD
KLSQYLLQLVQVCLSVCLCTWTNPLARFLIKKALTNQRIGHFFFWHLKSEMHNKTVSRRF
GLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQKTQMKFLVEHMSRPDY
MESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWDNPDIMSELLFTNNEVIFKNG
DDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVKNSYTIMQIQCKG
GLKGALQFNSHTLHHWIKDKNRGEGYDRAIDLFTRSCAGYCVATFILGIGDRHNSNIMVK
ENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQECTKTKEFERFQEMC
YKAYLSIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKSQQEALEYFTKQMN
DAHHGGWTTKMDWIFHTIRHMPNEH
>A0A7L1YAJ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scytalopus superciliaris|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEIILLE
IAGNCTVEQMKAQIWMRAVEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTVDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIPSD
AQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILSQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L4IMX5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pomatorhinus ruficollis|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTNNKHTKAPEILLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEQVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIVQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3P9H841|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MHPGIYGMLEEWEDGDQEINMDFLLPTGIFLKFPVSRNDTIKHIKEMVWRNARSEALFSG
LGDPDGYVFTCINQTAEREELEEEFRRIRDVKPFMCVLRLVAREGNRQEKLTNTQITQLI
GKGLHEFETQKNHEVNEFRTKMRTFCEEKALERQYLPWQRWLEYSFPCDLEPCRTPSGFG
SVKMKSSKIFINVKFEASDESFMLQQDCHDLPVALMKSALKKKATVFRSLRQEPEDYILQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPQVTMVHHSTVSRFQEEQSRMCNQMFKSRSL
SRPPPLPLKRQNTSSLWSINEPFYIQLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTS
LDVTVCSEPLWDQRLEFDINVCDLPRMSRLCFALYAVIEKTKKPKSTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSMWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRP
HPLYYPSLEKHLKLKEIMDNKHYTEFFEDEKDLLWKLRTEIREHYPENLSKLLLVTKWNK
REDVVQMVSLLKKWPDLPAIHALELLDYSFPDPAVRSFTVRCLRKLSDDELLQYLIQLVQ
VLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIH
HIKILNKQNEALAKMRALSDFVKSGSQKMTVEDLKLCIRQETYMEALSDLLSPLNPSIIL
TEICADKCRFMDSKMKPLWLMYKNPSTPGDMVGIIFKNGDDLRQDMLTLQMIQLMENMWK
KEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQLNSSNSAATAAFNKDALLNWLKSK
NPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRK
LGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYKILCRNGMLFVNLFAMMK
AAGLPELTCFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDN
RA
>H2LLC3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MHPGIYGMLEEWEDGDQEINMDFLLPTGIFLKFPVSRNDTIKHIKEMVWRNARSEALFSG
LGDPDGYVFTCINQTAEREELEEEFRRIRDVKPFMCVLRLVAREGNRQEKLTNTQITQLI
GKGLHEFETQKNHEVNEFRTKMRTFCEEKALERQYLPWQRWLEYSFPCDLEPCRTPSGFG
SVKMKSSKIFINVKFEASDESFMLQQDCHDLPVALMKSALKKKATVFRSLRQEPEDYILQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPQLTMVHHSTVSRFQEEQSRMCNQMFKSRSL
SRPPPLPLKRLVVQAGLFHGSELLCKVVTSLDVTVCSEPLWDQRLEFDINVCDLPRMSRL
CFALYAVIEKTKKPKSTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSMWPSVPDDKS
DLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPSLEKVLSTKKKHFHLKLKEIMDNK
HYTEFFEDEKDLLWKLRTEIREHYPENLSKLLLVTKWNKREDVVQMVSLLKKWPDLPAIH
ALELLDYSFPDPAVRSFTVRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERAL
SNRRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIKILNKQNEALAKMRALSDF
VKSGSQKMTVEDLKLCIRQETYMEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLM
YKNPSTPGDMVGIIFKNGDDLRQDMLTLQMIQLMENMWKKEGLDLSDKLEQAIEEFTLSC
AGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFV
HVIQQGRTNNSEKFERFREYCEQAYKILCRNGMLFVNLFAMMKAAGLPELTCFKDIQYLK
DSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRA
>A0A2Y9KD26|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Enhydra lutris kenyoni|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSEETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFAKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIRNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCSKTPALSGKVAAESPSSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDHGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVHVIETLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNANLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSSETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A4Y6GLV9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNLESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARICLSICSVKGRKGAKEE
HCPLVWGNVNLFDYKDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCPGLTSRLACDVSVSAADAEQLRCLCSKDP
LYELSEQGKDFLWRHRHYCVNIPESLPKLLMSVKWNSRDEASQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVKGLTDDKLSQCLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A4W2EZY8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos indicus x Bos taurus|TrEMBL
MCFYFMMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISCIKQMLW
KQVTNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPEL
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHSLIQFQVHVRAGLFHGTELLCKTVVSSEISGKNDHIWNE
PLEFDINTCDLPRMTRLCFAVYAVLDKVKTKKSTKTMNPSKYQTIRKSGKVHYPVAWVNT
MVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIKFPENKKQPY
YYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQ
DCRENFPHALPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYA
VGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVH
IPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMH
TCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVI
FKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADI
QLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSD
NIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFR
QCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTEEEALKQFKQ
KFDEALRESWTTKVNWMAHTVRKDYRS
>A0A4W2CS93|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos indicus x Bos taurus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLYMWPSVPDEKGELLNPWTVRSNPNTESAAALVIFLPEVAPH
PVYYPFLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQEH
FPEALARLLLVTKWNKHEDVAQMLYLLSSWPELPVLSALELLDFSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQ
ETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKNG
DDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A673HKP4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRVSEEKMQRMQLMSCGEWLRSCYSTQLGTGSLE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDY
VLRVSGRFEFLFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLAR
KTSNPPLPLPPKKRPPTQLHTCVWKVHSLFRINLVKGNKVNAEDTAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSP
RDALELLDFNYPDQYVREFAVICLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLER
AQSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVS
ELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLQSPLNPNILLAGVHVERCKYMDS
KMKPLWIVYNNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGC
LATGDRSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
HDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A673GHA2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVEMRDASGPHSQIIVVIWVIVSPNNDKQKY
TLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLKMCVQEYQGKYILKVCGCDEYLLEKYPI
SQYKYVRSCIMLGRLPNLISTISSLPCQSLTRFYVSFSTIKTKKIESNREIKTQPYYLQC
FNSACFINEHLNDLLQEHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGV
TGSNPNKETPCLELEFDHFSSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDH
AMTEADIEQLRQLSNRDPLSEITEQEKDFLWRHRQYCVNIPEVLPKILLAVKWNSRDEVA
QMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQVLAFFQL
LFWWKHAGRPQCFFLSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTD
ILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKR
PLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYG
CLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAIDLF
TRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLT
QDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSF
DDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A673IL04|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSAELPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKITHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDEYLLEKHPLSQYKYIRSCITLGRLPHLMLVSKDSLYSQLPSS
GFMAPSYSRRTPQPSPCPGGGDPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDEQQIEEHSSRLVCDSSISQADAEQLRTLCSRDPLYELSEQEKDFLWRHRH
YCVNIPESLPKLLLSVKWNSRDEVHNLDIFLRWKNAVLQMLETWLSKERLLSNSTPRFLT
DDEELTEQPSSLRQCSRLLYAEVLCLIINTSVFSEFSSKKLLIIQFFISTMHSSGHSCNA
INGTADWLMKLILHSDWLLQTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEEC
RIMSSAKRPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGL
DLRMLPYGCLSIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIRDKNKGEA
YDRAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKR
ERVPFVLTQDFLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCG
MPELQSFDDIAYLRKTLALEKNQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A7K4Y357|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Regulus satrapa|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTNNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMHALEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNADLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A0A0ASJ6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Charadrius vociferus|TrEMBL
SRMPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGL
GTGPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPK
MAAKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMR
YDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSF
AINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEM
HVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMM
HVCMKQETYLEALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGI
IFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIAN
IQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLTYVLGIGDRHSDNIMIRET
GQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAY
MILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALR
ESWKTKVNWLAHNVSKDNR
>A0A8C9A6E7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Prolemur simus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTKSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRTFSEEKIRSLVGLSWMDWLKQTYPPEH
EPSIFEYSEDKLYGGKLIVAVHFENSQDVFSFHVSPNMNPIKINELAIQKRLTVHGKEDE
ASPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVINRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRKSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAISIQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C9AVR6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Prolemur simus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSCNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARGWGA
GTLRLPNRAFLVNVKFEGSEESFTFQVSTKDAPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGRHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQGQKPR
TKPPPIPVKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVGPRAS
QEGCGPRRARAAPGGPLPPRLSQSGHLPCLGDSRPTRNIWPGPLILELGRHSECGRVTEE
EQLQLREILERRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLY
LLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLD
CELTRFLLDRALANRRIGHFLFWHLRYSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQ
GEALSKLKALNDFVKASSQKTTKPQTKEMMHVCMRQEAYLEALSHLQSPLDPSTLLAEVC
VEQCTFMDSKMKPLWIMYSNEQAGGNGCVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEG
LDLREALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKT
KFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALM
RAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKD
NRQ
>A0A8C8YVN1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Prolemur simus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C8ZT54|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Prolemur simus|TrEMBL
MELENYEQPVVLREDNGRRRRRMKPRSAVASLSPMELIPIEFVLPTSQRHSQSPETALLH
VAGHGNVGQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQALHRSPGQIHLVQRRAPSEETQAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLSKKIANNCIFIIIHRSTTSQTIKVSAEDT
PGTILQSFFTKMAKKKSLMDIPESLNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDDVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKVSADTSSSESKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPSPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLYDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGFNKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7L2X174|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pandion haliaetus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIRKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAL
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMVSLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A484D5C2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Perca flavescens|TrEMBL
MPPGKYGMQEEGDQELMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNARSEALFSALGD
PDAYVFTCINQTAEREELEEESRRISDVQPFMGVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFEAQKNHEVNEFRAKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPECGSVK
SKNTKIFINVKFEACDESFMLQQGIQDFPLALMKSALKKKATVFRSVRQEPEDYTLQVNG
RWEFIYGKHPMCQFKYMFSCLRNNQIPHLTMVHHSTISKYQEEQGRMCSQGYKTRSLSRP
PPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTTSEV
TVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVNT
MVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPL
YYPPLDKVSDMEKNGDAAIVTKEECMKLKEIMDNKNHTEFFEDEKDLLWKLRTEVRDHYH
ESLSKLLLITKWNRREDVVQMMSLLRTWRDLPAIHALELLDYSFPDPVVRSFTIRCLRKL
SDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLRSEIHVASVSLR
FGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDFVKSGSQKMTADDLKLCIRQESYLEA
LSDLLSPLNPSIILAEICADKCRFMDSKMKPIWLMYNPFTQEDMVGIIFKNGDDLRQDML
TLQMIQLMENLWKREGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAA
FNKDALLNWLKSKNPEDKLDRAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFH
IDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCR
NGMLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKT
KKKEKLDQEGATGAGGMNREEAPGKSPEDMYIQQKVRVLLMLKKMGSNLTPSEEAFLRNY
AGVVHSQMSQLPQHNIDQGAEDVVMAFSRSETEDRRQ
>A0A6F9CID0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coregonus sp. 'balchen'|TrEMBL
MTTHTALTAVTHRPRHMCQVGPAALAARGPFHHRVKQHATSSYCARLIPTSPPSAYAPPL
TQGMCVGAVLSQPGRRDGVCMLMCRHAGQDSAANGFPDPGHLTRSPDQNPTVGTAVSSTQ
PTRLCVHRSHAKRRKKMSVSDFKSDPLLHRGRCVLQPTERTQAHVSCWRGSQAYRDCRGA
GNPQAPGPRSQAYRDCGGAGNPLLWKQAQSYPLFPSLGEMEGHMFECVNQAAVHEELEDE
TRRLCDVRPFWPMLKLVTRNCGRAERLLDSKIGVLIGKGLHELDALLDQEVKDFRSKMFR
ISEEKMQRVQLMTWSDWSQGEEPQPVTDCVNDKQAEASLKVTMHFDQSQDTASLKVCPST
SPSELMEQALRKWLTTHGPEEEGRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKE
CPHLTLVQVSTVQAMFEKEISAIGAVVNRKSSNPPLPLPPKRRGPLQVHTCVWEVSTQFK
IVLIKGSKVNAEETAKVQVRAGLFHGTELLCKPAVSSESSGRSEHVWNRTLDFDIAVSDL
PRMARLCFAVYAIMDKVKKQKSTKNAHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKT
GDIILHSWSSFPDELEEMLNPIGTIQTNPYTENATALHIHLPDYNPHPIVFPPFDKILEK
AAEIAGSSDCSTMGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLP
KLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMRAQC
NRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELI
KLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMD
SKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYG
CLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
THDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A7L0XFJ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tyrannus savana|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLIKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPNPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDTKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3B4AGN1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Periophthalmus magnuspinnatus|TrEMBL
MPPAMTDLVDIWGAHSPLSGHAPAHITVDFLLPTGMYIQMEVPREATIQHIKLLLWKQAQ
SFPLFSALGEMESHMFECVNQEAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRLSEERMQKVQMMSCTEWLQTSFSQQPETG
PGPDQVNGVSDRTTDLKVTIHFDLSQDSASLKVPLTCTPSELMEMAVKKWLTTHGSEEEA
SRYFLRISHSLEFLCGDHPLIQYKYIRTCLHAKDSPHLTLVHSSTIKELFDKEICAIRAV
VSRKTCTLPLPLPPKRRPTVQVRAGLFHGAELLCKPAVSSESSGRSEHTWRDSTLEFDIS
VSDLPRMTRLAIAIYAVMDKVKKQKSTKNTHINKYQTIRKSGKVLYPIAWVNTMVFDYKG
HLKTGDIILHCWSSFPDELEEMLNPIGTVQTNPYTENATALHINFPEYLSHSIVFPPFDK
ILEKAAEIARANDCSRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRHDCRENFPQSL
PKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVCCLRDMSDE
ELSQYLLQLVQVLRYEPYYDCALTHFLLERAQRNRKIGHFLFWHLRSEIHMPAVSVQFSL
ILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSKAKEAMLTKEAMMTCLR
QSGYSDALSDIHSPLNPNVLLAAVNVEKCRYMDSKMKPLWIVYNNKLLDGDTLGIIFKNG
DDLRQDMLTLQILRLMDLLWKEASLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTS
SNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMV
RSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCE
DAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDE
ALRESWTTKVNWMAHNVAKDNRS
>L5M4E1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myotis davidii|TrEMBL
MPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISSIKQMLWTQIHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEHESSILE
NLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHWKEDEVSPYDY
VLQISGRVEYVFGDHPLIQFQVHVRAGLFHGTELLCKTIVSSEISGKNDHVWNEPLEFDI
NTCDLPRMARLCFAVYAVLDKVKTKKSTKTINASKYQTIRKSGKVHYPVAWVNTMVFDFK
GQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIRFPENKKQPYYYPPFD
KIIEKAAEIASSDSANVSLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSD
EELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLSVGHMKVLSKQVEA
LNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEK
CKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLR
MLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLD
RAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRER
VPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPEL
TSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A669CYY7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKSKNIKKIFINVKFEASDESFMLQQDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTITKYQEEQGRMCSQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKVPSPKRLHKTMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLRKL
SDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASVGLR
FGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESYLEA
LSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLRQDM
LTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATA
AFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLF
HIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILC
RNGTLFVNLFAMMKAAGLPELTSFKDIQYLKVCHSNDVAVNDYEENNNNVNNLWFLVFKR
TL
>I3JNU1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDSEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A851KXH3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vidua chalybeata|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSNSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQYMGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLL
RSGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIS
SDLQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSS
VKWGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLDDDD
VLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAV
ILEAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQ
GSKLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHG
DDLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQST
VGNTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMIT
ETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVK
AYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVC
RDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A250YLX5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Castor canadensis|TrEMBL
MELENYDQPVVLREDNLRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRHSKTPETALLH
VAGHGNVEQMKAQVWLRALEISAAADFYHRLGPDSFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRRVPSEETLAFQQQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPEYLLKKIANNCIFIIIHRSTTSQTIKVSADDT
PGIILQSFFTKMAKKKSLMGIPESLNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLIVFVEANIQHGQQVLCQKRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKTPALSGKVSAETHSSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEGD
RVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPEAYPKLFSSVKWGQQ
EIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLL
QLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYL
RGCGMAMLQDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLPQ
SFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQD
MLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGA
FKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLF
HIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSSHFQKFQVCVKAYLALRH
HTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTV
QFNWFLHLVLGIKQGEKHSA
>A0A8C8GB76|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
YIFVSVTQDAEREEFYDETRRLLCVVMIILFSVPYFIGQIIVVIWVIVSPNNNKQKYTLK
IKHDCVPEQVIAEAIRKKARSMLLSPEQLKMCVQEYQGKYMLKVCGCDEYLLDKCSKRFV
CWALMKASPYFFCCLFFLLSMKIYVRIGVYHGGEQICDNVNTQRVPCSNSKWNEWLTYDM
YIPDIPRLPPLSLHLLCERQEGEEGGKHSEHCPLAWGNVNVYDCTHTLVSGKMALNMWPV
PRGLVDLPQPHRSHRLQPQQGKHETPCLELEFDYFNYPVKFPDMTTVEEHANWTISRELG
FNYYQSGQSKRVARDHTLTDSDSEQLRQVRNRDPLFEITEQEQDFLWKHMYNYTFPKILL
AVKWNSRVEVAQVTCLFLTLWRLASNKPEQAMELLDCNYSDPMTRDFAVRCLEKYLTDDK
LSQYLIQLVQQYLDNPLVRFLLKKAFTNQTIGLIFLALKMHNKTVSQRFGLLLESCFHAC
GMYFKHLCRQVEATEKLINLTNILKQEKDETQKVQMKFLVEQMRTPDYMNALQNFTFPLN
PAHRLGNIRPLWLNWENPDIMSEILFQNNEIILKNGDNQGLDLRMLPYNCMSLGDRVGLI
NVGALQYNSSELHKYDLAIGLFTRSCAGYCVTTFILGIGDRHNSNIMVKDDGQVGPEFSS
YCHDFLQTLLHTEMCYKAYLAIRQHTMALDKTEQEALDYIMKQMNDAHHGGWTPKMDWIF
HTICQHALN
>A0A3P9N1C6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia reticulata|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFIEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIMSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKIYVRTGIYHGGEPLCENVNTQRVPCSNPRWNEWLTYDIYLADLPRSA
RLCLSICSVKGRKGAKEEHCPLAWGNVSLFDYMDILVSGKVALSLWPVPHGLEDLLNPIG
VAGSNPNKETPCVELEFSRFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDS
SVSAADAEQLRSLCSRDPLYELSEQEKDFLWRHRHYCLNIPESLPKLLLSVKWNSRDEVS
QMYCLLKEWPLMEPESALELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVLKY
EMYLDNPLARFLIKKALTNQRIGHFFFWHLKSEMHNKTISRRFGLLLEAFCRACGMYLKH
LNRQVEAMDKLVNLTDTLKQEKKDETQKTQMKFLVEHMSRPDYMESLQGFVSPLNPVHQL
GNLRLEECRIMSSAKRPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIME
NIWQNQGLDLRMLPYGCLSIGDRVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWI
KDKNHGEAYDRAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHK
KKKFGYKRERVPFVLTQDFLIVISKGIQESTKTKEFERFQEMCYKAYLAIRQHASLFINL
FSLMLGCGMPELQSFDDIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHT
IRHMPNEH
>A0A8C8LR75|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
IELQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQALQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDC
HRKFRFKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFN
IRIRDLPKGARLSLQISKGTSSYQDNGGSPVGGGSGNHDCNKTKSRLLYYVNLLLVDHRS
LLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYPVALPKSR
EGERGQREMPNHLRKQFEAIVETDPLHPLSQEDKELLWHFREECMRHPRAYPKLLGSVRW
GRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLETLGDDDVLR
YLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLE
AYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQVVFQLRQKLENLQTSG
LPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTTLSSDTIGVIFKDGDDL
RQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSVVGS
TGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLGVGDRHNDNIMITESG
NLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVRAYL
ALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRTEEEAQRHLLDQIEICRDK
GWTVQFNWFLHLVLGIKQGVDKRSA
>A0A3P9PM09|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia reticulata|TrEMBL
MPPGKYGTQEEWEQDGDREIYMDFLLPTGIFLKFPVSRTDTIRNIKKMVWKNASREALFC
GLGDPDLYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRSEKLTNAQISLL
IGKGLHEFEAQKNHEVDEFRAKMRTFCEEKSLERQNLPWQRWMEYSFPCELEPCCSLATG
GSSKSKHGKKLFVNVKFESSDESFMLQQDSQDLPVALMKSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGQHPLCQFKYIFSCMRNGQNPQLTMVRQCTISKYQEAQGRVCSQMYKTR
SLSRPPPLPLKKLVVQAGLFHGSELLCKMMTSSEVTVCSEPLWDQRLEFDINVSDLPRMS
RLCFALYAVIEKTKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSMWPSVPDD
KNDLLNPMGTVQKNPNVDSAAGLLIRFPNIRPHPLYYPPLEKVYLKLKEIMDNKNYTEFF
EDEKELLWKLRIEVRDYFPECLSKLLLITKWNKREDVVQMVSLLKSWPELPAIQALELLD
YSFPDPAVRYFTIRCLKKLSDNELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIG
HFLFWHLKSEIHVASVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDIVKTGSQ
KMTVEDLKLCIRQESYLEALSDLLSPLNPSVILFEICADKCRFMDSKMKPLWLMYKNPLE
QADMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRDKLDQAIEEFTLSCAGYCVA
TYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQG
RTNNSEKFERFREYCEKAYKILCRNGTLFVNLFAMMKAAGLPELSSSKDIQYLKDSLALG
KSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A851KK10|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vidua chalybeata|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETAGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K7AUT9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothoprocta ornata|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSGNLSSMELISIEFILPTSNKHTKVPEMILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHMFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTSLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
LPGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSALDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVLL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITEA
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7M4F7E3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crocodylus porosus|TrEMBL
MISSGMELGNHEQPVVMREENKRRRRRMKPYCTANNLSSMELIPIEFVLPTSPKHTKTPE
TVTLEIAGNCTVEQMKAQIWMHAIEMSQTSDFCHKYTPDQFIFQYQKKGQWYEIYDKHQV
IQTLDCILYWKVLQKKVGKIYVVQKQKPSEEVQEFQKQLNDLIGYDVTDVSNVHDDELEF
TRRRLVTPRMIEVACRDPKLYSMHPWITSKPLPEYLFKKITNNNIFINIHRGTTSQKIKV
SIDDTPDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHCIRQ
CLKNGEEIHLVLDTPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLW
DCNRKFRVKIIGIDIPVLPRNTDITVFVEANIQHGQQLLSQRRTTSKPFTEEVLWNTWLE
FDIKIKDLPKGALLNLQVYCGKTQSLATKASLQSHDSPSSDSKCKTQLLYYVNILLIDHR
FLLRSGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAVSIVLDKYCHPIALPKH
RITSDTQGDGARTEMPNQLRKQLEEIIATDPLNPLTAEDKELLWHFRYESIKHPKAYPKL
LSSVKWGQQDLVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLE
DDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQR
FAVILEAYLKGCGKAMLHDFMKQVQVIELLHTVTMEIKSVSAEKYDVTSQVITQLKQKLE
KLQNNKLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIF
KHGDDLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQ
QSTVGNTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNI
MITESGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGSSGKKTSQHFHKFQDV
CVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQI
EVCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A671WHW6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MDGKQIQVSDEEPRVVREETRRRRRKKAITSSSCSSMDQITVEFVLPTTARGGNSPDTVL
LDVAGNWTVEQVKAQVWLKAVTLNLCHDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTRKLLPDHLLSKVSNNHILVVIHIGTVSQTIKVSID
DPPAQVLASFFAKTANKRVLLGIPDDMCEEDFVLRVCGREEYLYGEKPLHNFNWIRQCLK
NGEEIHLVLESPPDPELDQVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQRGLFLSVRFSGKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPE
KSEESSSSINADKLTSATNPDKASAMAIAILLDKYCYPVVLPKSRDVGRDVGAGGEEAEG
GERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRWG
KQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRY
LLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEA
YLRGCGEDMLQDFRKQVEMTEALQKVTREVKAMSADKYDITAQVVFQLRQKLENLQSSGL
PESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLR
QDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGST
GAFKDEILYQWLRDKCVSEDKFQQAVEKFLYSCGGYCVATYVLGIGDRHNDNIMITESGN
LFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLA
LRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKG
WMVQINWFVHLVLGIKQGVEKRST
>A0A671TR63|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSSVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTDQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFESTDCFSTFFFLASFPSVG
>A0A7L4CI98|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nyctiprogne leucopyga|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVLWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELVDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWMAWMEYNFPLQLEPTAKGLGT
GALHTHNKNIFVNVKFQSGGESFTFQISPAEFPITLMSYAIKKQATVFRHETVENPGDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHKGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMP
AKPPPLPKKKPNYGSLWSLEQSFSIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVAVRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEEMGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3P9A3B3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPAMTDLMDMWAAHSQVSGDNLVSVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQTY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALPDQEVKDFRSKMFRISEEKMQRVQLMNWSEWLQACFCPQLEPVVG
AAAGTDGVNDKQAETSLKVTIHFDQSQDTASLKVCPSTTPSELMEQALRKWLTTHGPEEE
GRQAQQYILRVSDKLEFLCGDHPLIQYKHIKACLQSKECPHLTLVQISSVKDMFEKEISA
IGAVVNRKSSNPPLPLPPKRRGPSVNTCVWEVPLPFKIFLIKGSKVNAEETAKVQVRAGL
FHGTELLCKPAVSSESSGRSEHVWNRMLEFDIQVSDLPRMARLCFAVYAIMDKVKKRKST
NNSHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDITLHSWSSFPDELEEMLNPIG
TIQTNPYTENATALHIQFPDYIAHPIVFPPFDKILEKAAEIARSSDCSPMGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLSPRDALELLDFNYPDQYVREYAVGLELLYLVVQPRANLRSSAPICSDEELSQYLLQ
LVQVLRYEPYYDCALTRFLLDRGQGNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYCRG
SIPHIEVLKKQVEALSKLKSVNELIKLGTIKNVRSKTKEAMLTKEAMMTCLRQSGYTETL
SDLHSPLNPSVLLSGINVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDML
TLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAA
FNKDALLNWLKEKNSGDALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFH
IDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRR
NGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTT
KVNWMAHNVVKDNRS
>A0A3Q7PUV0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinus ursinus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECFKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVDCLRQMRSEVHIPAVSVQFGVILEAYCRGSVGHMKV
LSKQVGKLIFQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSP
LNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLR
LMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDAL
LNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHI
LGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFI
TLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMA
HTVRKDYRS
>A0A7L4F5P1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alopecoenas beccarii|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKALAT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMP
TKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWRQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEPPRAVPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C6XAI2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Naja naja|TrEMBL
MPPRPSSGELWGMHLMPPKILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVELRDANAPHSRALYVCPPNIESSDLPKHI
YNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLKL
CVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMTKESLYAQLPLDT
FAMPSYSRRISTATPYMNGEASAKSLWAINSHLRIKILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLKYELFVFDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFS
SPVKFPDMSVIEEHANWIISREQGFNYNHAGLSNRIARDNELRDNDKEQLRAICTRDPLS
EITEQEKDFLWSHRHYCVSMPEILPKLLLSVKWNSRDEVAQMYCLIKDWPQIRPEQAMEL
LDCNYPDPMVRAFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQ
RIGHFFFWHLKSEMHNKNVSQRFGLLLDSYCRACGMYLKHLSRQVEAMEKLINLTDILKQ
EKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLWL
NWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSI
GDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDPAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAY
IRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A4W5LWS9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDTQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLPEP
GGNKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVV
TSCEVNVCSEPLWDKKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPHFDKVHLLLHTLDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKLLLITKW
NKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQL
VQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGN
IYHIKNLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLLSPL
NPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIFKNGDDLRQDMLTLQMIQL
MEILWKKEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDF
GHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGT
LFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVN
WMMHSLAKDSRL
>A0A4W5PQX4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MPPRPSSGELWGMHLMPPSIMVDCLLPNGMILTLECTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDAEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVSIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERYMQGECFLKRLHGEL
>A0A7K8NG27|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Casuarius casuarius|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFSPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIISD
PQGDKTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCAKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K5HPU7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crotophaga sulcirostris|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQNEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDTVQDPEVNDFRTKMCQFCEERAAKRQQLNWAAWMEYSFPLQLEPMTKGLGT
RPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHQGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTDSAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAAEDPDEKLQLKEILERRSYTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNRHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELLQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKSLNDFVKSSSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFSNEETGRGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRHHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C2X3Z3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MPSGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNASSEALFG
ALGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRMFCEEKAQERQMLPWQQWMKYSFPCDLEPCCSPPDG
CLLLALMCLSQESFMLQQDPQDLPVALMRSALKKKATVFRSLRQEPEDYTLQVNGRWDFI
YGKHPMCQFKQNTSSLWCISEPFYIHLLQGSRVNAGEGMKLVVQAGLFHGSELLCKVVTT
SEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVLEKAKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSTWPSVPDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPH
PLYYPPLDKVPIPKGLYLVSENILICYQISGGNMENNGDTTIATKEEVRLYISHCLILTQ
LKVHTKTYMKLKEIMDNKNSTEFFEDEKELLWKLRTEVRDHFHESLSKLLLITKWNRHED
VVQLVSLLKNWRDLPGIHALELLDYSFPDPAVRSFTIRCLRKLSDNELLQYLIQLVQVLK
YESYLDCDLTTFLLERALSNWRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIR
LLTKQNEALGKMKALSDFVKSGSQKMTADDLKLCIRQESYLEALSDLLSPLNPSIILAEI
CADKCRFMDSKMKPLWLMYNPGAQEDMVGIIFKKGDDLRQDMLTLQMIQLMENLWKKEGL
DLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPED
KLDPAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGIN
RERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNATLFVNLFAMMKAAGL
PELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A8C2X2S7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MPSGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNASSEALFG
ALGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRMFCEEKAQERQMLPWQQWMKYSFPCDLEPCCSPPEY
GSVNGCLLLALMCLSQESFMLQQDPQDLPVALMRSALKKKATVFRSLRQEPEDYTLQVNG
RWDFIYGKHPMCQFKYIFSCLRNGQNPYLTMVHHSTIHKYQEDQGSMYNQVYKSRSLSRP
PPLPLKKVRVQRTTVLVVQAGLFHGSELLCKVVTTSEVTVCSEPLWDQKLEFDINVADLP
RMSRLCFALYAVLEKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSV
PDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPLDKVPIPKGGGKTLHFTLS
NSHTYMKLKEIMDNKNSTEFFEDEKELLWKLRTEVRDHFHESLSKLLLITKWNRHEDVVQ
LVSLLKNWRDLPGIHALELLDYSFPDPAVRSFTIRCLRKLSDNELLQYLIQLVQVLKYES
YLDCDLTTFLLERALSNWRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIRLLT
KQNEALGKMKALSDFVKSGSQKMTADDLKLCIRQESYLEALSDLLSPLNPSIILAEIWLV
ADKCRFMDSKMKPLWLMYNPGAQEDMVGIIFKKGDDLRQDMLTLQMIQLMENLWKKEGLD
LRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEDK
LDPAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINR
ERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNATLFVNLFAMMKAAGLP
ELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A8C9WCS5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MAPGVYCLPNMWEGGVQQVKMDFLLPTGIYLSFGVSGNDTIGAIKKTLWRNAKNEPLFFA
LSDPDAYVFTCINHTAEQEELEDEQRRLCDVRPMMPILRLVAREGDRVEKLITSQISLLI
GKGLFIHEFDTMKNHEVNEFRTKMRTFCEELAMDRQRLPWQKWIEYSFPCDLEPCALLSH
SGNLRNRASKKIIVNVKFEASDESFTLQVEPQEVPLTLMKSALKKKATVFRPMKQEKPED
YALQVNGRWEFIYGNFPLCQFKYIFNCLHSGVTPHLTMVHYSTITKYQEEQGGISREISK
NRSSSKPPPLPLKKTLVVIIRNMRFVPQLVVQAGLFHGSELLCKVVTSSEVNVCSEPVWD
QKLEFDINVCDLPRMTRLCFALYAVIEKSKKPRSTKKKNKKADCPLSWVNTMVFDYKDQL
KTGEYYLSTWPSTDLLNPMGTVEINPNTDSAAGLLIRFQNVRPHPIYYPSLDKVSWTVEL
HFSILYFSTNVQSFVQKSFLAHLKVSEIVENKNYTEFFEDDKEILWKLRYEVREKYSESL
SKLLLITKWNKHEDVAQMVSLLQKWPDLPALHALELLDYSFPDRNVRSFTIRCLRKLSDD
ELFQYLLQLVQVLKYESYLDCDLTKFLLERALSNKKIGHFLFWHLRSEMHVPSVNLRFGL
ILEAYCRGSIYHMKTLMKQNEALNKMKSLNDFVKSASQKGTRTQTTGEMKKCIKQETFME
ALSDLLSPLNPSLILSEIWYRCKYMDSKMKPLWLVYKNEKVQGDPLGIIFKNGDDLRQDM
LTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATA
AFNKDALLNWLKSKNPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLF
HIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYKILC
RNGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWK
TKVNWMVHSVSKDNR
>A0A8C9SKF4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLISIKQQLFAEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAMEEREGGGAHSQALYVYPPNVESSPDLPQH
IFCKLDKGRLIVTIWVIVSPSNAKQKYTLKIAHDCLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIVVGRLPHLMLVSKDSLYSQLPAS
GFVAPSYSRRTPQPSPCPGGGDPSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTELPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDTLVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVIFPDEQQIEEHANWVISRELGSWKVRLACDSTVSQVDVEQLRSLCSRDPLYELS
EQEKDFLWRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLRDWPLMQPESALELLDCNF
PDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHF
FFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMEKLVNLTDTLKQEKKDE
TQKMQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENP
DIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVG
LIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTRSCAGYCV
ATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISK
GVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTL
ALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A0N8K321|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
AGTMPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYP
LHQLLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREI
GFAIGMPICEFDLVKDPEVQDFRRNILNVCKESVDLRDASGPHSRALYVYPPNVESSPEL
PKHIYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSPE
QLKMCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKESLYSQL
PTDTFAMPSYARRISTATPYMNGEASAKSLWTINGTLRLRVLCATYVNVNIRDIDKIYVR
TGIYHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIADIPRAARLCLSICSVKGRKGAKE
EHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGITGSNPNKETPCLELEF
DYFGSPVKFPDMATIEEHANWSISRELGFNYCHAALSNRLARDNTLTDIDSEQLRLVCNR
DPLSEITEQEKDFLWRHRHYCVNMPEILPKILLAVKWNSRDEVAQLLDCNFPDPMIREFA
VHCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEM
HNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFL
VEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQ
NNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEAVRNSH
TIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDLAIDLFTRSCAGYCVATFILGIGD
RHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVICKGTQECTKTR
EFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEA
LDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A7L2Z9X8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Jacana jacana|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTTSNLSSMELISIEFILPTSNKNTKVPEMMLLE
IAGNCTVEQMKAQVWMRAIEMSQTTDFYHTFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFINIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIGTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8B9VF43|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas zonorhyncha|TrEMBL
CHKFDVTGGNLLNPFFLPVGVISYFTRLFHPAVIPSQVVWKHAQYEPLYHMLSDPEAYVF
TCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHEFDS
MQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKAEVAACTRGGKLFV
YGWERSTDPSSFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYTLQVNGKYEYLY
GNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANTPKMSPKPPPLPKKKV
KGHGSFVNGSNPRGLTVFSYFFSPQLVVQAGLFHGNEMLCKMVSSSEVNVCSEPVWKQRL
DFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVSKDCPIAWVNVMLFDYKDQL
KTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPNVASHPVYYPSFDKPF
GLRLSPLYALFCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLL
IITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDNELFQ
YLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEA
YCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCMKQETYLEALSH
LQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIFKNGDDLRQDMLTL
QMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFN
KDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHID
FGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHG
LLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKV
NWLAHNVSKDNRQ
>A0A2Y9E158|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Trichechus manatus latirostris|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLV
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWEAWLQYSFPLQLEPAARGWGT
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVERPEDYA
LQVNGKYEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPTPQVQKLR
TKPPPIPVKKPSSASLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVSVCSGPVWNQRLEFDINICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEQCLYMWPFVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
HPVYYPALEKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
YFPEALARLLLVTKWNKHEDVAQMLCLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHVCMR
QETYLEALSHLQSPLDPSTLLADVCVEQCTFMDSKMKPLWIMYSNEEAGSEGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
EKAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q1JH61|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQSKYILKVCGCDEYLLEKHPISQYKYIRSCMMLGRLPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHSNWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRYRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNALHQWLKDKNKGEMYDLAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A7N6AWF0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETKRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDTEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPID
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMATIEDQANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRACEGSILHFTQKQDCVNMPEILPKILLAVKWNSRDEIAQMYCLLK
DWPAIKPEQAMELLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNP
LARFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEA
MEKLINLTDLLKQEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEE
CRMMSSAKRPLWLNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQG
LDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGE
MYDQAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYK
RERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGS
GMPELQSFDDIAYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8C6QZC9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nannospalax galili|TrEMBL
MPPGVDCPMEFWTKEESQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAALRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVERPEDYA
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPAKKPSSVSLWSLEQPFCIELIEGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVICLPEVAP
HPVYFPALEKILELGRHGERGRITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLGALELLDFNFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPHTKEMMHMCMR
QETYMEALSHLQSPLDPSTLLEEVCLCRPHSLQCTFMDSKMKPLWIMYSSEEAGSAGSVG
IIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIA
NIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFER
FRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHF
RVKFNEALRESWKTKVNWLAHNVSKDNRQ
>H2Y5F4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ciona savignyi|TrEMBL
MSPSSTHSSASGELWGFPLMPNKVSVDILLPTGIFISVETSRECGLMELKDTVWSLAKEQ
PLFDLLSENNSYIFVGITKDAELEEFYDEHRRLCDIHLFQPVLKLVAAKGNREEKILQQT
ITQAVGVSVDEFNRIKNPEVDDFRREIGNFCKSDVEKRNQNSDAHSLIAYTYPPKVELSP
KLPLHTMENLLSNTNIVIRVWVVQENSFQTHASVCVPCDSTPLMIISEVVKKKVLNNHNN
VLSKEYINEQYVLKVCGWNEYLEGNFPICQYKYIRQCVNKGELPDVMLESTKQVMKRIPE
HMPYMQPNLNKQKAGKESRSCIMSHALTQKFRVHVNIGSYLNVADIPRCAKLCIAVCGVR
RKKDEHWPLAWANIPLYNYTGKLIQGKHTVRLWHPPCHMDGMLNPIGVTGSNPQKEETPC
LELEFDSFRFHKLLNEIILGIMQNFLFLHLLKLIMKIYSIMSIASRDPLCHLNEHEKLLL
WRCREQCRNIPQSLPKLLQSVKWQERECVQEIHSLLKSWPTLSPEQAIELLDCKYPDLEV
RKFATSCLNVGLTDDGMLKYLLQLVTALKFELYLDNPLVRFLLQRAIANLRIGHYLFWHL
KSEMYDIQISRRFGLILEAYCRSCGPYLEQLVRQTEILTKLQNVNTILQKDDNVSQKALR
EYLQKPDYEELLQNNLSPLNPAYKLENLRTNFCELKSSAKRPITLQWHSADPLAEYFQPV
HGILFKNGDDLRQDMLTLQILRVMDDIWQNDNLDLCISPYICISMGQNVGMIEIVQNAET
IMSVQKKGGVVGSLQLKTGTLHQWLKDHNPGEKQYNKAIHNFTRSCAGYCVATLVLGIAD
RHNDNIMIKKNGQMLHIDFGHFLNHKKKKYGICRNRVPFVLPGDFMRIICRGATTDLSKT
YDYKNFVDLCCRAYLSIRSHANVIINLFCMMLGAGLPELSSFDDIEYIRTSLAVEKEELQ
AVQYFRDCLTAAQDKQWTTKVDWVCHAVRHSVRK
>A0A8C6DQN5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Moschus moschiferus|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVGHRSPGQIHLVQRRSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRNPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKRADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKKDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>F7DHK6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Equus caballus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLV
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPLAGNWGA
STLRFPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRLEYLYGSYPLCRFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPTPQVQKPR
TKPPPIPVKKPSSVSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRNNPNTESAAALVISLPEVAP
HPVYYPALDKILELGRPGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKATKPHTKELMHLCMR
QETYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>H2Y5F5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ciona savignyi|TrEMBL
MSPSSTHSSASGELWGFPLMPNKVSVDILLPTGIFISVETSRECGLMELKDTVWSLAKEQ
PLFDLLSENNSYIFVGITKDAELEEFYDEHRRLCDIHLFQPVLKLVAAKGNREEKILQQT
ITQAVGVSVDEFNRIKNPEVDDFRREIGNFCKSDVEKRNQNSDAHSLIAYTYPPKVELSP
KLPLHTMENLLSNTNIVIRVWVVQENSFQTHASVCVPCDSTPLMIISEVVKKKVLNNHNN
VLSKEYINEQYVLKVCGWNEYLEGNFPICQYKYIRQCVNKGELPDVMLESTKQVMKRIPE
HMPYMQPNLNKQKAGKESRSCIMSHALTQKFRVHVNIGSYLNVAPKWNQWLVFETKVADI
PRCAKLCIAVCGVRRKKDEHWPLAWANIPLYNYTGKLIQGKHTVRLWHPPCHMDGMLNPI
GVTGSNPQKEETPYNFGDYAELSIPSLVETNNEDLRSIMSIASRDPLCHLNEHEKLLLWR
CREQCRNIPQSLPKLLQSVKWQERECVQEIHSLLKSWPTLSPEQAIELLDCKYPDLEVRK
FATSCLNVGLTDDGMLKYLLQLVTALKFELYLDNPLVRFLLQRAIANLRIGHYLFWHLKS
EMYDIQISRRFGLILEAYCRSCGPYLEQLVRQTEILTKLQNVNTILQKDDNVSQKALREY
LQKPDYEELLQNNLSPLNPAYKLENLRTNFCELKSSAKRPITLQWHSADPLAEYFQPVHG
ILFKNGDDLRQDMLTLQILRVMDDIWQNDNLDLCISPYICISMGQNVGMIEIVQNAETIM
SVQKKGGVVGSLQLKTGTLHQWLKDHNPGEKQYNKAIHNFTRSCAGYCVATLVLGIADRH
NDNIMIKKNGQMLHIDFGHFLNHKKKKYGICRNRVPFVLPGDFMRIICRGATTDLSKTYD
YKNFVDLCCRAYLSIRSHANVIINLFCMMLGAGLPELSSFDDIEYIRTSLAVEKEELQAV
QYFRDCLTAAQDKQWTTKVDWVCHAVRHSVRK
>A0A3Q4GAG1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neolamprologus brichardi|TrEMBL
MAPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLTTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYSNNPHCAGTKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLKMCVQEYQGKYILKV
CGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMDFFTMPSYARRISTA
TPYMNGETATKNLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGIYHGGEQLCDNVNTL
RVPCSNPRLWNEWLTYDMYIPEVPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYT
HTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHYSSPVKFPDMSTIE
DHANWNISRELGFNYCHTGLSNRLARDNPLTDGDNEQLRQVCNRDPLSEITEQEKDFLWR
HRHDCINMPEILPKILLAVKWNSRDEVAQVLKYEQYLDNPLARFLLKKALTNQRIGHFFF
WHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLKQEKKDEAQ
KVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWENPDM
MSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLI
EVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRSCAGYCVAT
FILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGT
QECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLAL
DKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A3Q4GIP6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neolamprologus brichardi|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVIEFRTKMRAFCEEKAQDRQSLPWQKWMEYSFPCELEPCRSLPQS
LKSKNSKKIFINVKFEASDESFMLQQDPHDLPLALMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNCQNPHLTMVHYSTVTKCQEEQGRMCSQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPSVPDEKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKICDMERNGDLSLATKDEHSKLKQIMDNKNYTEFFEDEKELLWKLRTEVRD
HYPESLSKLLLITKWNKREDVVQMVNLLRNWPDVPAIHALELLDYSFPDPAVRSFTIRCL
RKLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASV
GLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESY
LEALSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLR
QDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSA
ATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYK
ILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDNRP
>A0A5E4ABZ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Marmota monax|TrEMBL
MLSDPKAYVFTCVNQTAEQQELEDEQQRLCDVRPFLPMLCLVTRQGDRMEKLINSQISLL
IGKGLHEFDCLQDPEVNDFRTKMRQFSEEAPAHRQELGWEAWLQYSFPLQLEPSTRRWGD
SNTSQISNPDLLVNVKFEGSRESFIIQVSTKDVPLALMACALQKKAKVYQHLTMEKPEDY
VLQVNGRHEYLYGSYLLCQFKYICSCLHSGLNPHLTMVHSSSILAMRDEQSKPAPQVQKP
HTKPPPIPMKKPSSVSLWSLGQPFCIELIQGSKINADEQMKLVVQAELFHGNEMLCKTMS
SLEVSMCSEPMWKQHLEFDTNICDLPRMARLCFALYVVMEKAKKARSSKKKSKKVAGTLR
TGVLGEPGDPSLSARPSLAP
>A0A3Q3LVH6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDSVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYSQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYISDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGITGSNPNKETPCLELEFDHF
SSPVKYPDMNAIEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>U3IL41|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos platyrhynchos|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GLLHTPTKNIFVNVKFQSGGESFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANTPKMS
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPNVAS
HPVYYPSFEQLLELGRNGEPPRTAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDNELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8D1KBG9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MCFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDYPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSSRGGKKFLAVLKEILDR
DPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPR
EALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLKTLNS
LIKLNAMKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMK
PLWLVYNNKVFGEDSIGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLAT
GDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLS
CAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8D0U8Y3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPGVDCPMEFWTKEENQSVDVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSDPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLL
QLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRYSEMHVPSVALRFGLIMEAYC
RGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQ
SPLDPSPAPDGCAPGSVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNGDDLRQDML
TLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAA
FNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFH
IDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYAILRR
HGLLFLHLFALMRAAGLPELSCSKDIQYLKVNARAGPIRRPGGPRCPS
>A0A7L1SVU3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aramus guarauna|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSIEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSIAL
HPVYYPSFEQLLELGRNGEQPRIAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A0S7K0U3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poeciliopsis prolifica|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLINIKQQLFIEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIMSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLENFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCENVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVSLFDYMDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
RFSQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSATDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCLNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDRVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNHGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLMLGCGMPELQSFDDI
AYLRKTLALGKTGE
>A0A8B9XRV2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus grunniens|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A218UL22|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lonchura striata domestica|TrEMBL
MSVQSLTDIQMNNYKEIQLNALPFFSHTVEFGGVNTISSGMELGDHEQPVVMRDENKRRR
RRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLEIAGNCTVEQMKAQIWMRAIE
TSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLDCILYWKVLQKKVGKIYVVQK
QKPSEEVQELQRQLNDLIGYDVTDVSNVHDDELEFTRRRLVTPRMIEVACRDPKLYAMHP
WTTSKPLPEYLFKKISNNNIFIIIHRGTTSQKIKVSIDDTPDMILHSFFTKMAKKKSLMD
IPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNGEEIHLVLDNPPDPNEDEVQK
EEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRKFRVKIIGIDIPVLPRNTDLT
VFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKIKDLPKGALLNLQIYCGKAQG
PSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRSGEYVLHMWKIPGKGEEQGSI
NADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSDPQGDRTRAEMPNQLRKQLEE
IIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQEIVAKTYQLLAKKEAW
DQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLDDDDVLHYLLQLVQAVKFEPYHDSAL
ARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLHDFMKQVQ
VIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGSKLPESFRVPYDPGLRAGALV
IEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWEA
ESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEILNQWLKERCMI
EEKAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGIN
KERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAYLALRHHTNLLIILFSMMLMTGM
PQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVE
KHSA
>A0A7L3RYQ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cepphus grylle|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8B9LYW4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Accipiter nisus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKIAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLPSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIESLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
RLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GELFFENFIEVGTVYILH
>A0A8C0TRF4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNDFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPNDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKNI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKSRGGKKFLAVLKEILDRDPLSQLCENEMDL
IWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQ
YVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWH
LRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNKAK
GKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGE
DSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTS
ETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGI
GDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTE
KFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEA
LKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8I3PWT3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNDFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPNDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKNI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNKAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C0NVL6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MEPQGREPRVVLREDHRRRRRRMKARGPAAGLPSMELIPIEFVLPTSQRSSKAPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYQRLGPDHFVLLYQKKGQWYEIYDRYQVVQTLD
CLRYWQLLHRSPGQIHVVQRRAPSAATLAFQRQLTALIGYDVTDLSNVHDNELEFTRRRL
VTPRMLEVAGRDPELYAMHPWVTSKPLPDYLRKRIPNNCVFIVIHRGTTSQTVKVSADDT
PGAILRSFFAKMAKKKALMGIPEGQSERDFVLRVCGRDEYLVGDTPLQNFQWVRQCLKNG
EEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRR
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFSIKI
KDLPRGALLNLQVYCSKAPTLSAKASADAPGAGSEARGKAQLLYYVNLLLIDHRFLLRRG
EYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDP
EGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKW
GQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLH
YLLQLVQNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLEAYLRGCGTAMLHDFTQQVQVIE
MLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLPESFRVPYDPGLKAGALVIEK
CKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESL
DLYLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCAIEEK
FQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINK
ERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMP
QLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKH
SA
>A0A5A9NAT2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Triplophysa tibetana|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELLKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESAADLPQH
IYSKLDKGRLMVTIWVIVSPSNSKQKYTLKITHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCITLGRLPHLMLVSKDSLYTQLPAS
GFVAPSYSRRTPQPSPCPGGGDPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDIPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVNGKLALGLWPVPHGLEDLLNPIGVSGSNSNKETPCVELEFP
WFNQTVVFPEEQQIEEHANWIISRELGYSYCLGLTSRVACDSTISQSDGEQLRTLCSRDP
LYELSEQEKDFLWRHRHYSVNIPESLPKLLLSVKWNSRDEVSQIYCLLKDWPLMQPESAL
ELLDCNFPDPMVREFALRCLIQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGSLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIKEKNKGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKNQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A3B3R435|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Paramormyrops kingsleyae|TrEMBL
MPPGVYGLQGIWEDGGQQVDMDFLLPTGIYLNFAVSRNDTIRTIKKIVWKNAKKEPLFYA
LSDPDAYVFTCINHTAEQEELEDEQRRLCDVQPLMPILRLVAREGDRVEKLITSQISLLI
GKGLHEFDSLKNQEVHEFRTKMRAFCEERALDRQRLPWQKWMEYSFPCELEPCPLSGTLK
TQGIKKIIVNVKFEASDESFTLQVEPQEVPLTLIRNALKKKATVFRPMKQEKPEDYTLQV
NGRWDYIYGNYPLCQFKYIFNCLCTGLTPHLTMVHHSTINKFQEEQGGMNSQVSKNRPPT
KPPPLPLKKQTTSSLWSIQDPFVLHLVQGSRVNADEGMKLVVQAGLFHGSELLCKVMTSS
EVNVCSEPVWDQKLEFDISVCDLPRMARLCFALYAVTEKSKKPRSTKKKNKKADCPLSWV
NTMVFDYKDQLKTGEYNLSMWPSVPDDKSELLNPMGTVEINPNTESAAGLLIRFPNIRPH
PIYYPSLSKVHMKLREIVENKNYTEFFEDDKEILWKLRYEMFEKYPESLSKLLLITKWNK
HEDVAQMVSLLQLWPELPALHALELLDYSFPDPNVRSFTIRCLRRLSDNELFQYLLQLVQ
VLKYEPYLDCELSKFLLQRSLSNRKIGHFLFWHLRSEMHVPSVGLCFGLILEAYCRGSIY
HMKALMKQNEALNKMKSLNDFVKSASQKGTRTQTTGDMKVCIKQEAYLEALSDLLSPLNP
SLILSEICPDICKYMDSKMKPLWLVYKNEKVQGEPLGIIFKNGDDLRQDMLTLQMIELME
ILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNNAATAAFNKDALLNW
LKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGN
FKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCELAYKILCRNGTLFVNLF
SLMRAAGLPELSSSKDIQYLKDSLALGRSEEEALKNFKVKFNEALRESWKTKVNWMVHSV
SKDNR
>W5MA77|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lepisosteus oculatus|TrEMBL
LFPTMPPAVMDTLDIWAVDSQLTNDVCVAVDFLLPTGIYIQMDVPREATIQHIKLLLWKQ
AQSYPLFSFLGEMESYMFECVNQSAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAEKL
LDSKIGVLIGKGLHELDALQDPEVKDFRTKMFRISEDKMQKLQMMTWMEWLQCYFSPVLD
STVPDGIQDKLNVTMHFSHSQDTASLAISPYMTPNDLTEQAVKKWLTTHRSEEEVNSSEY
VLRVSTRLEFLFGEHPLIHYKYVKTCMMCNESPHLTLVECSTVKEMFEKEISAVGTVVNR
KSSNPPFPLPPKKRGVSQISTCVWDVAEPFRITLIKGSKVNAEETVKVQVRAGLFHGTEL
LCKPAVSSETCGKNEHVWNKTLEFDINVCDMPRMTRLCFAVYAVMDKVKKQKSTKNIHAT
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGELILHGWSSFPDELEEMLNPIGTVQTNP
YTENATALHIHFHECTKSAVIYPPFDKILEKAAEIARGSDCMPMVSRGSKKFHIELKEIM
ERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWNKHEDMAQLQALLQIWPKLS
PRDALELLDFNYPDQYVREYAVNCLRDMSDEELSQYLLQLVQVLRYEPYYDCALSRFLLE
RAQANRKIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALCKLKAV
NELIKLGTLKNARNKTKEAMLTKEAMMTCLRQTGFAETLSDLQSPLNPSILLSGIHVERC
RYMDSKMKPLWVVYNNKLLAGDTLGIIFKNGDDLRQDMLTLQILRLMDMLWKEANLDLRI
VPYGCLATGDRTGLIEVVSASETIANIQLTSSNVAATAAFNKDALLNWLKEKNSGDALDR
AIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERV
PFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRKNGNLFITLFALMLTAGLPELT
SVKDIQYLKDSLALGKTDEDALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C4NU01|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MPPAMTDLLDIWAAHSPLAGHALDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLISKGLHELDGINDQEVKDFRSKMFRMSEERMQKVQMMTCMEWLEACFSPQLEPA
PGTAITDGLNDRPADLKVTIHFDQSQVRVCSPVFTPIDLMELALRKWLTTHGPEEEAWRG
QYVLRVSHCLEFLCGDHPLIQYKYIRTCMQAKESPHLTLVHTSAIKAMFDKEISAIGAVV
GRKSSNPPLPLPPKRRTCVWGVSSPFKIVLVNGSKVNAEETAKVQVRAGLFHGTELLCKP
AVSSESSGRSDHTWKDSTLEFDISVSDLPRMTRLCFAIYAVMDKVKKQKSTKNAHINKYQ
TIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTE
NATALHIHFPEYSSHPIIFPPFDKILEKAAEIARANDCSRGGKKFHIELKEIMERDALSQ
LCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALEL
LDFNYPDQYVREYAVGCLRDMRLTYASTHTYIFIQHSGLLFISFNEELSQYLLQLVQVLR
YEPYYDCALTHFLLERAQRNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIE
VLKKQVEALSKLKSVNELIKLGTIKNARKAKEAMLTKEAMMTCLRQSGYSETLSDLHSPL
NPNVLLSGINVEKCRYMDSKMKPLWIVYNNKLMGGDTLGIIFKNGDDLRQDMLTLQILRL
MDLLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALL
NWLKERNTGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHIL
GNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFIT
LFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAH
NVAKDNRS
>A0A7K7PC98|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acrocephalus arundinaceus|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDSTISQIKQLLWKQA
HSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLAGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEFD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMTGRGGKKFYVVLKDI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLRHMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8B9D211|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anser brachyrhynchus|TrEMBL
MFMYRCNLTLLSLCECIRPTLPSSPRLLISSGMELGDYEQPVVMREENKRRRRRMKPYCT
SSNLSSMELIAIEFILPTSNKHTKIPEMMLLEIAGNCTVEQMKAQIWMRAIEMSQTTDFY
HAFTPDQFILQYQKKGQWYEIYDKHQVLQTLDCILYWKVLQKKVGKIYVVQKQKPSEEVQ
EFQRQLNNLIGYDVTDVSNVHDDELEFTRRRLVTPRMIEVACRDPKLYAMHPWTTSKPLP
EYLFKKITNNNIFIIIHRGTTSQKIKVSIDDTPDMILHSFFTKMAKKKSLMDIPEDHSEL
DFVLRICGRDEYITGETPIKDFHWIRQCLKNGEEIHLVLDNPPDPSEDEVQKEEWPLVDD
CTGVTGYHEQLTIDGKDHERVFTISLWDCNRKFRVKIIGIDIPVLPRNTDLTVFVEANIQ
HGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKIKDLPKGALLNLQIYCGKAQGLSTKTNLQ
SHDSPNSDSKCKTQLLYYVNLLLIDHRFLLRSGEYVLHMWKIPGKGEEQGSINADKLTSA
TNPDKENSMAISIVLDKYCHPIALPKHRITSDSQGDRTRAEMPNQLRKQLEEIIATDPLN
PLSPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQEIVAKTYQLLAKKEAWDQSTLDVG
LTMQLLDCNFSDENVRAMAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRG
LRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLHDFMKQVQVIELLHKV
TMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSSKLPESFRVPYDPGLRAGALVIEKCKVMA
SKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWEAESLDLCLL
PYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEILNQWLKERCVIEEKFQAAV
ERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPF
VLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSK
EDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L3YJF5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fregetta grallaria|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVLWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQNPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRCLTPHLTMVHSSTIITMRDEQTNCIASPPKTA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMRSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A674ERS4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPRPSSGELWGMHLMPPSIMVDCLLPNGMILTLECTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDAEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVSIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERYSICSFVNVSFPIGEY
>A0A673X9X4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPAMTNLMDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQQVQLMTWSEWLQACFSPQLEPGGG
DTALSLQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEEGRQAEQYVLRVSDKLEFLCG
DHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISAIGAVVNRKSSIPPLPLPPKR
RGPSVSHVLNTCVWQVSTHFKIVLIKGSKVNAEETVQVRAGLFHGTELLCKPAVSSESSG
RSEHVWNSTLEFDITVSDLPRMTRLCFAVYAVMDKVKKQKSTKNAHINKYQTIRKSGKVH
YPVAWVNTMLFDYKGQLKTGDIILHSWSSFPDELEEMLNPIGTIQTNPYTENTTALHIHL
PDYNPHPILFPPFDKILEKAAEIAGSSDCLPMGRGGKKFHIELKEIMERDPLSQLCENEK
DLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYP
DQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLNRAQCNRNIGHFLF
WHLRSEMHMPAVAVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNAR
SKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMDSKMKPLWIV
YNNKLLGGDTLGIIFKNGDGTRGCISMVLIMNHWNKMCLCRIVPYGCLATGDRSGLIEVV
SSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKAIEEFTLSCAGYCVATYV
LGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTG
NTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTD
DEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A7K5W9J9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hylia prasina|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCPSSSFSSMELISIEFILPTSDKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIPSD
AQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKSDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFQKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7J6AAB3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ameiurus melas|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDSEVQDFRRSILSVCREAMEEREGGGPHTHALYVYPPSVESSPQLPQH
IYAKLDKGRLIVTIWVVVSPSNAKQKYTLKIAHDCVPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGKLPHLMLVSKDSVYDQLPCS
GFVTPSYSRRTPQPSPSPGGGDPANPRSLWTFNAHTPLRIRLICATYVNVNIRDIDKIYV
RTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLMYDISLTDLPRSARLCLSICSVKGRKGAK
EEHCPLAWGNVNLFNYKDTLVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELE
FPSFNHTVVFPDEQQIEEHANWIISRELGYNYSLGLSNRLVCDSSISQAEAEQLRALCNR
DPLYELSEQEKDFLWRHRHYCVNIPESLPKLLLAVKWNSRDEVSQMYCLLRDWPLMQPES
ALELLDCNFPDPMVREFALRCLMQGLTDEKISQYLLQLVQVLKYEMYLDNPLARFLVKKA
LTNQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRSCGIYLKHLNRQVEAMDKLVNMTD
TLKHEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKR
PLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYG
CLSIGDCVGLIEVVRNSFTIMQIQCKGGLKGALQFNSNTLHHWIREKNKGETYDSAIDLF
TRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLT
QDFLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHAGLFINLFSLLLGCGMPELQSFD
DIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A8C0IR16|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelonoidis abingdonii|TrEMBL
MPPAMTDILDIWAVDSQIGADGLISVDFLLPTGTYINLDVPRDATICHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVKEFRSKMRRISEEKLLSLVGLSWVDWLKHSYPPEQEPSIPE
NFQDKLYGGNLVVAIHFDKCQDVFSFQVSPNINPVKLNELAIRKRLTIHGKEDEVDPSDY
VLQISGRLEYIFGDHPLIQFQYIHKCVMNRILPHLTLVECCSIKKMCEQEMIAIEGAINR
KSSNLPLPLPPKKTRTVTSVWDISNPFKIMLLKGNKLNTEETAKVHVRAGLFHGTELLCK
PIVSAEISGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKTINPSKYQ
TIRKAGKVHYPVAWVNTMVFDFKGQLKSGDLLLHSWTSFPDELEEMLNPMGTVRTNPYTE
NATALHIKFQEYSNLPIYYPPFDKILEKAAEIAKSSENAGMAGRGGKKFYIELKEIMERD
PLTQLCENEMDLIWTLRYDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWSKLPPRE
ALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLVERAL
ANRRIGQMLFWHLRSEVHIPSVSIQFGVILEAYCRGSIAHMKVLSKQVEALSKLKTLNSI
IKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELYVEKCKYMDSKMKP
LWIVYNNKMFGGDLLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGCLATG
DHSGLIEAVSAAETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSC
AGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFI
HVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C0QJJ6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelonoidis abingdonii|TrEMBL
MPPGIYCPVEFWSKEENQTIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWHHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVRDPEVNDFRAKMRQFCEEKAVKRQQLSWMTWMEYNFPLQLEPLAKGPRT
GPLRIPNKNIFVNVKFESGGESFTFQVSPKEFPVTLMSYAIKKQATVFRHQTVESPEDYT
LQVKGKCEYLYGNYPLYQFQYIRSCLHHGLMPHLTMVHFSSIIAMRDEQTNCTAHTPKMV
SKPPPLPKKKPTHESLWSLNQPFYIELMQGSKVNADERMKLVVQAGLYHGNEMLCKMVSS
AEVNVCSEPVWKQRLDFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQSNPNTESAAALVICFPSVTP
HPVYYPSLEQLLELGRNGEYARATLEDPEEKQQLREILERRSHTELYEHEKDLVWKMRYE
IRDQYPEALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFTI
NSLKKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLERALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSNYHMKVLMKQGEALNKMKALNDFIKVSSQKATKPQAKEMMHV
CMKQETYLEALSNLQCPLNPTIILAEVCVDQCTFMDSKMKPLWIVFNNEEADGRGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRD
YCEKAYMILRCQGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A093EZQ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gavia stellata|TrEMBL
SRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMARGL
GTGLLHIPTKNIFVNVKFQSGGESFTFQISPEEFPITLMSYAIKKQATVFRHETVENPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPK
MSAKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLYMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSI
ASHPVYYPSFEQGLSGLSKSSGLRLSPVYALSCDSHEQKLQLKEILERRSHTELYEHEKD
LVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPD
RYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFW
HLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKLSSQKTTKP
QTKEMMHVCMKQETFLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETG
RGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMH
SDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGFFLPSFFEEFSLSCAGYCVATYVLG
IGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNN
EKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEE
ALKHFRLKFNEALRESWKTKVNWLAHNVSKDNR
>A0A7N9CY41|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca fascicularis|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPFSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDIHICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7L3IIR7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pardalotus punctatus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWQHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYSFPLQLEPMAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQRPEDYT
LQVNGKCEYLYGNYPLCRFQHIRSCLQRGLTPHLTMVHFSAIVAMRDEQTNCIASPPKAA
SKPPPLPKKKPNYGCLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSS
SEVSVCSEPVWRQRLDFDISICDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALLICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKQQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFDNEETGGSGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L1HB85|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nycticryphes semicollaris|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPNEFPITLMNYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQPFHIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAL
HPVYYPSFEQLLELGRNGDQSRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C9BU17|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phocoena sinus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
AKPPPIPLKKPASVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKQLQLREILERRGSGELYEHEKDLVWKMRHEIQEHFPEALARLLLVTKWNK
HEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQ
VLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTH
HMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMQLCLRQETYLEALSHLQSPLDP
STLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKNGDDLRQDMLTLQMIQLM
DVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLN
WLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLG
NFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHL
FALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHN
VSKDNRQ
>A0A8J4NJH2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eudyptula minor|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEERGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERQVF
RGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFR
LKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6J3HNV8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sapajus apella|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRSCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKAMHRSPGQIHLVQRRAPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKYLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKAPAESPSSESKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCYPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIETLQKVTLDIKSLSAEKYDVSSQVIAQLKQKLENLQNSHLP
KSFRVPYDPGLKAGALAILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIA
KIQQSTVGNTGAFKDEVLNHWLKEKSPTEDKFQAAVERFVYSCAGYCVATFVLGIGDRHN
DNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSQHFQKF
QDICVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFL
DQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A3Q1F662|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acanthochromis polyacanthus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKSNRVARDHALTE
SDTEQLRQLSNRDPLSEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYC
LLKEWPSIRPEQAMELLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYL
DNPLARFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQ
VEAMEKLINLTDILKQEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLR
LDECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQ
NQGLDLRMLPYGCLSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKN
KGEMYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKF
GYKRERVPFVLTQDFLIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMM
LGSGMPELQSFDDIAYIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQH
ALN
>A0A8C8AUK3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Otus sunia|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3B3WMU3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia mexicana|TrEMBL
MPPGKYGTQEEWEQDGDREIYMDFLLPTGIFLKFPVSRNDTIRNIKKMVWKNASREPLFF
GLGDPDLYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRSEKLTNAQISLL
IGKGLHEFEAQKNHEVDEFRTKMRTFCEEKSLERQNLPWQRWMEYSFPCELEPCSSPATG
GSSKSKHGKKLFVNIKFESSDESFMLQQDSQDLPVALMKSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGQHPLCQFKYIFFCMRNGQNPQLTMVHHSTISKYQEDQGRVCSQMYKTR
SLSRPPPLPLKKLVVQAGLFHGSELLCKMMTSSEVTVCSEPLWDQRLEFDINVSDLPRMS
RLCFALYAVIEKTKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGDFLLSMWPSVPDD
KSDLLNPMGTVQKNPNVDSAAGLLIRFPNIRPHPLYYPPLEKVYLKLKEIMDNKNYTEFF
EDEKELLWKLRIEVRDYFPECLSKLLLITKWNKREDVVQMVSLLKSWPELPAIQALELLD
YSFPDPAVRYFTIRCLKKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIG
HFLFWHLKSEIHVASVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDIVKTGSQ
KMTVDDLKLCIRQESYLEALSDLLSPLNPSVILFEICADKCRFMDSKMKPLWLMYKNPLE
QADMVGIIFKNGDDLRQDMLTLQMIRLMENLWKKEGLDLRMIPYGCLSTGNKTGLIEIVK
SSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVL
GIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNN
SEKFERFREYCEKAYKILCRNGTLFVNLFAMMKAAGLPELSSSKDIQYLKDSLALGKSED
EALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>L5JSW8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pteropus alecto|TrEMBL
MELENDEQLVVLREDNCRRRRRMKPRGSAASLSSMELVPIEFVLPTRQRTSKSPEIVLLH
VAGHGNVEQMKAQVWLRALETSVVADFYHRLGPDNFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHSPSEETLAFQRQLTALMGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEKDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPAQDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNSDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCGKAPVLSGKAPAETPSSESKGKSQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPNPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGE
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQRVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVVEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETVIH
ALFYTYSCLSLFHPLVVTRPCSSISKMAHLFNAHIKYLLNFKYCARHKEDLSIALGKDIC
AKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEDDAKKYFLDQIE
VCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A7K5R157|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Prunella himalayana|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWQQAQREPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEERAARRQQLGWAAWMEYNFPLQLEPVAKGPGT
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGRTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSS
AEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3B3Y8H3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia mexicana|TrEMBL
MPPGKYGTQEEWEQDGDREIYMDFLLPTGIFLKFPVSRNDTIRNIKKMVWKNASREPLFF
GLGDPDLYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRSEKLTNAQISLL
IGKGLHEFEAQKNHEVDEFRTKMRTFCEEKSLERQNLPWQRWMEYSFPCELEPCSSPATG
GSSKSKHGKKLFVNIKFESSDESFMLQQDSQDLPVALMKSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGQHPLCQFKYIFFCMRNGQNPQLTMVHHSTISKYQEDQGRVCSQMYKTR
SLSRPPPLPLKKQNTSSLWSIHEPFYIHLVHGSKVNADEGMKLVVQAGLFHGSELLCKMM
TSSEVTVCSEPLWDQRLEFDINVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGDFLLSMWPSVPDDKSDLLNPMGTVQKNPNVDSAAGLLIRFPNI
RPHPLYYPPLEKMVSLLKSWPELPAIQALELLDYSFPDPAVRYFTIRCLKKLSDDELLQY
LIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLKSEIHVASVSLRFGLILEAY
CRGNIHHIKLLSKQNEALGKMKALSDIVKTGSQKMTVDDLKLCIRQESYLEALSDLLSPL
NPSVILFEICADKCRFMDSKMKPLWLMYKNPLEQADMVGIIFKNGDDLRQDMLTLQMIRL
MENLWKKEGLDLRMIPYGCLSTGNKTGLIEIVKSSDTIANIQRNSSNSAATAAFNKDALL
NWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFL
GNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEKAYKILCRNGTLFVN
LFAMMKAAGLPELSSSKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMH
SLAKDNRP
>A0A8B8WYL7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balaenoptera musculus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPLKKPASVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKQLQLREILERRGSGELYEHEKDLVWKMRHEIQEHFPEALARLLLVTKWNK
HEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQ
VLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTH
HMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDP
STLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKNGDDLRQDMLTLQMIQLM
DVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLNKSNMVATAAFNKDALLN
WLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLG
NFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHL
FALMRAAGLPELSCAKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHN
VSKDNRQ
>Q3UVA4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|TrEMBL
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLD
CLHYWKLMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIANNCIFIVIHRGTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMNISESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
DEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFAEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPSLSSKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRHGDY
VLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSNLP
ESFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTE
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGSSGKKTSPHFQKFQDVCVRAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>B0QZL5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|TrEMBL
MPPGVDCPMEFWTKEESQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLRVSNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYA
LQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMKAGLFHGNEMLCKTVSSSEVN
VCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAWANLM
LFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVIYLPEVAPHPVY
FPALEKILELGRHGERGRITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQEHFPE
ALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRKLT
DDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSVALRF
GLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQETY
MEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFKNGDDL
RQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNM
AATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRES
GQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAY
TILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALR
ESWKTKVNWLAHNVSKDNRQ
>A0A4Z2B811|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu bimaculatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKHPISQYKYIRSCIMLGRMPNLMLMAKDSLYSQLPTD
NFVMPSYSRRISTATSYMNGEVAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYISDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSSVKYPDMNAVEDHASWTISREVGLNYTLSGQSNRAARDHILTEGDSEQLRQLTNRDPL
SEITEQEKDFLWRNRYYCMNIPEILPKILLAVKWNSRDEVAKMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECVKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKTEQAMMLFSFLISTHPVEESFKCLPLSDGLFYTLWFPTGGVGLLHETDER
CSSWWMDHQDGLDIPHN
>A0A1L8GTX9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus laevis|TrEMBL
MLSSGMELDNYEQPVVLRDENQRRRRRMRPHSATTSVFSMDLIPIEFIMPTINRCSKVQE
TMLLEVAGNCSVEQMKAQVWMHAIEKSHNSDFYQRLTPDQFLLQYQKKGQWYEIYDKHQV
IQTLDCIMYWKVLQKTVGKIHIVQKEKTPEEMIEYQKTLNYLIGYDVTDVSNVHDDELEF
TRRRLVTPRMIELSRRDARLYSMDPWVTSKPLPEYLCQRITSNSIFIIIHKGMTSHTIRV
SIDDTPDVILHSFFTKMAKKKSLLEISEENSELDFVLRVCGRDEYIIGNAPIKDFHWIRQ
CIKNGQEIHLVLEKPPNALKDDVQKEEWPLVDDCTGVTGYHEQLTIEGKDHEKIFTISLW
DCNRKFRVKIIGIDIPVLPKNTEIIVFVEANIQHGQQVLSQRRTTCKPFTEEVLWNSWLE
FDLKIKDLPKGALLNLQIFCGKAPNVSIKSNALSPESAASDSKFKNQLLYYVNLLLIDHR
FLLRQGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKETSMAISISLDKYCHPVALPKH
KLVSDPELERPRTEMPNQLRKQLEEIIATDPLHPLTPEDKELLWHFRSEIIKHPEAYPKL
LSSVKWGQQEMVAKTYQLLSKREAWDDCILDVGLTIQLLDCNFSDENVRAMAVQKLESLQ
DDDVLHYLLQLVQAVKFEPYHDSALSRFLVKRALQSKRIGHFLFWFLRSEIAQSMHYQQR
FAVILEAYLRGCGKAMLDDFTKQVQVTEILHKVTMEIKSVSAEKYDVTSQVITQLRQKLE
KLQNAKHPDKLPDSFRVPYDPGLRAGSLVVEKCKVMASKKKPLWLEFKCSDTTALSNETI
GIIFKHGDDLRQDMLILQILRIMGSIWEAESLDLYLLPYGCISTGNKIGMIEIVKDATTI
AQIQQSTVGNTGAFKDEVLSQWLKEKCPIEEKFSAAVERFVYSCAGYCVATFVLGIGDRH
NDNIMVTESGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSQYFNT
FQDVCVKAYLALRHHTNLMIILFSMMLMTGMPQLTSKEDIEYIRDSLTVGKNDESAKKHF
LDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L1E6J4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oenanthe oenanthe|TrEMBL
MPPGIYCPSEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWQQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAAQRQQLGWAAWMEYSFPLQLEPVAKGLAT
GSQQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETPQRPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAILAMRDEQNNCITSPPKVA
CKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWRQRLRFDISVCDLPRMARLCLALYAVLEKARKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKVLIVTKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A665UAK1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MSPGKYGMQEDWEKDGVQEIMMDFLLPTGILLNFPVSRNDTIKNIKRMVWKNARSEALFN
ALGDSDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNHEVNEFRSKMRTFCEEKAQERQQLSWQQWMEYSFPCDLEPCCFPCGS
AKSKNTKKIFINIKFEESFMLQQDPQDLPEALIRNALKKKATVFRSVRQEPGDYTLRCNG
TWEFIYGNHPLCQFKYIFSCLRNGQNPHLTMVHHSTISKYQEEQGRMCSQVYKTRSLSRP
PPLPLKKQNTSSLWSINEPFYIHLVQGNRVNADEGMKLVVQAGLFHGSELLCKVVTSSEV
TVCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPIAWVNT
MVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIHFPNIRQYPL
YYPPLDKVYLRPREERQKERQLFYLKLKEIMDNKNYTEFFEDEKELLWKLRADVREYYPE
SLSKLLLITKWNKREDVVQMVSLLRNWPDLPVIQALELLDYSFPDPAVRSFTVRCLRKLS
DDEILQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASVSLRF
GLILEAYCRGNIHHIKLLAKQNEALGKMKALSDFVKSGSQKMTAEDLKLCIRQESYLEAL
SDLLSPLNPSIILEEICADKCRFMDSKMRPIWLMYKNQWAQGDMMGIIFKNGDDLRQDML
TLQMIQLMETLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNNSNSAATAA
FNKDALLNWLKSKNPEEKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFH
IDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTSNSEKFERFREYCERAYKILCR
NGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKT
KVNWMMHSLAKDNRP
>A0A1S3GSZ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dipodomys ordii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKSNRLARDNELRE
NDKEQLRAICTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYC
LVKDWPPIKPEQAMELLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYL
DNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQ
VEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLR
LEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQ
NQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKN
KGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKF
GYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMM
LGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQH
ALN
>A0A4U5VWY3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Collichthys lucidus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKLIEPLGNREEKILNREIGFA
IGMPVCEFEMLKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVCQMYCLLKEWPLMEPETAL
ELLDCNFPDLMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMLKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHAGLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A091RDP8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Merops nubicus|TrEMBL
SRMPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRVKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPLAKGL
GPGPLHTPTKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPK
MVAKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKKSTKKKSKKADCPIA
WVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVA
SHPVYYPSFEQVGDMGTSSGRHRGSPALLASGLRLSPVYALSCDCHEQKLQLKEILERRS
HTELYEHEKDLVWKMRHDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNA
LELLDFSFPDRYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALS
NRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFV
KVSSQKATKPQTKEMMHMCMKQETYLEALSHLQSPLNPNIILAEVCVEQCTFMDSKMKPL
WIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGD
KTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCA
GYCVATYVLGIGDRHSDNIMIRETGQV
>A0A5N3XSR2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Muntiacus reevesi|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
SLRFGLIMEAYCRGSTHHTKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGAVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C5A1Y1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
LPVSLSLSLLWKQAQTYPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVL
RLVTRNCGRAERLLDSKIGVLIGKGLHELDALQAQEVKDFRAKMLRVSEARMQFYHAMTW
SEWLQACFSPQMETTGAAPPAASSYTSLRVSPAFTPTEVMEQGLKKWLTTHGPEDDSRQG
PYVLRVSQRLEFLCGDHPLIQYKVCEPLRPRSTVSTSARIHLPLVTPPAPQVQVRAGLFH
GTELLCKPAVSSESSGRSEHAWSDGTLEFDIVASDLPRMTRLCFAVYAIMDKVKKQKSTK
NTHSNKKPCPPPAWVNTMVFDYKGQLKTGDVILHSWSSFPDELEEMLNPIGTIQTNPYTE
NATELSLSISSPLPRSFSPPTLPPLPSLSLSLPSLFSSHPSLSSLPSLSLLPPLLLSSLF
QGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRHDCHLKFPQSLPKLLLSVKWSKHE
DMAQLQALLQIWPRLSPRDALELLDFNYPDQYVREYAVRCLREMSDEELSQYLLQLVQVL
RYEPYYDCALTRFLLERAQANRKIGHFLFWHLRSEIHMPAVSIQFALILEAYCRGSIPHI
EVLKKQVEALSKLKSVNELIKLGTIKTARSKTKEAMLTKEAMMTCLRQSGYSETLSDLNS
PLNPSIQLSGINVERCRYMDSKMKPLWIVYHNKLLRGDSLGIIFKNGDDLRQDMLTLQIL
RLMDLLWKENSLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDA
LLNWLKEKNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGH
ILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEDAYLILRKNGNLF
ITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWM
AHNVAKDNRS
>A0A1A7XU39|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Iconisemion striatum|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFKAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTQEQLK
MCVQEYQGK
>A0A452QLP3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus americanus|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRHSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLLDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIQI
KDLPRGALLNLQIYCSKAPAPTGKGSADTPGSEGKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLEAY
LRGCGTAMLHDFSQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQLMCCDVCVKA
YLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCR
DKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A8C5AM16|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MDPHTICAASGEEDCGALSRTRRRRKGITSASLSAMDQITIEFILPTTPKNGLSPHTTLL
EVPGNWTVEQVKAQVWLRAVASNFSPDFYHKFSPDHCILLYMKKGTLCEIYDKHQVFQTL
DCIRYWRALKKDVGRISLVFRPPQQDEALRYQRFLNQLIGYDVTDVSNVHDDELEFTRRK
LLTPRRNELQERDPRLYAVDPWLTDRPLRDHLLSKVMNGHLLVVIHIFTTSQTIKVSIDS
TPEQVLASVFAKTANKRALVGIPDDVCESDFVLRVCGREEYLYGDRPLQDFSWIRRCLKN
GEEIHLVLEKLPDTDLDQVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNR
KFRVKVLGIDIPLLPRNPDLTVYIEASIFHGQQLLAQERTTSKPFMEEVLWNTWLEFDIK
IRDLPKGARLNLQVGSKPPTQSSPIDTGKSKTRLQYYVNLLLVDHRSLLRQGEFVLHMWK
IPEKGEESSSSVNADKLTSATNPDKASSMAVAVSLDKYCYPVVLPKSRDSGGDSGEPGGE
RGQREMPNHLRKQFEAILAKDPLHPLSPEDKELLWHFRHECMRHPRAYPKLLASVRWGRQ
EDVQAAHAMLERSSAWDSSGLDVGLALQMLDCNYSDAQVRSMAVRKLETLGGDDVLRYLL
QLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIVQSLHYQQRYAVLLEAYL
RGCGDAMLTDFHKQVEVTEALQKVTREMKAMLADKYDVSSQVVFQLRQTLEALQSSGLPQ
TFRVPYDPGLRAGTLMIEQCKVMASKKRPLWLQFKRADPSSLSSDPIGIIFKDGDDLRQD
MLILQILLIMESIWETESLDLYLLPYGCISTGNRIGMIEIVKDAATIANIQQSVVGSRGA
FKDEILNQWLRDKCVNEDRFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLF
HIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTAGKKSSPHFQKFQDVCVKAYLALR
HHTNQLIILFSMMLMTGMPQLTSKEDIDYIREALTVGRSEEEAERHLLEQIEICREKGWM
VQINWFVHLVLGIKQGVEKRST
>A0A8C1RVK0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWVESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQNIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKRISEEKMQCMQLMSWGEWLRSCYSMTLEAGSLE
NLIDKHEGVIKITMHYDQSQDTSSLKVSLHCTVTELMDLALKKWQTTHVPEEDIGFRSDY
VLRVSRKLEFLFEDHHLNQCKYIRDCLLTNESPHLTLVHCDVVKAMFEKEISTIGSVLAW
KTSNPPLPLPPKKRLPTASTLFPALQLIKGVLSFIQVRAGLFHGTELLCKTAVSSESSSR
SEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHY
PIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFP
EYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMERDPLSQLCENEKD
LIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPD
QYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFW
HLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFGTIKTKTK
QAHLKEAMMTYLCVCRCKYMDSKMKPLWIVYNNKLLGGDTVDIIFKNGDDLRQDMLTLQI
LRLMDLLWKEANLEYRIVPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKD
ALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFG
HILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNL
FITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNW
MAHIVAHPS
>A0A8C2AAT1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGLCHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVA
QSGKSRSVKKILVNVKFEGSEVSEFMLIYHSFMLSGNSFLWYNAIKKSTVFRAAKQEKPE
DYTLQVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQMS
RTRAPSKPPPLPLKRVRMHFYTGTRSVINRGTTCHLSLVLVVQAGLFHGSELLCKVVTSN
EVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRDCPLAWVNT
MVFDYKDQLKTGEFSLSTWPSVPGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYP
PIEKVHFCVIAFCCFQLNELGMNGEKVHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQ
RYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHVRSFTIRCL
RNLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRSEMHVPSV
SLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIK
QDTYMEALSDVVSPLNPSIVLCELCTDKCKFMDSKMKPLWLMYKNKYDHVGIIFKNGDDL
RQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNS
AATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRET
GQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAY
KILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKVNWMMHTFAKDNR
>A0A8C2ATM1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKTLILTDGTVFFQHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQRYPES
LPKLLLITKWNKHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLSD
DELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSLRFG
LILEAYCRGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYM
EALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQDML
TLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAA
FNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMISETGQLFH
IDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCR
NGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKT
KVNWMMHTFAKDNR
>A0A8C1FVI1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRLVVQAGLFHGSELLCKVVISNEVSVCSEPVWDQKLVFDISVSDLPRMSR
LCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFSMSTWPSVPDDKG
DLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKVNFVVLLNVSHETERDCGHK
NYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVSLLRKWPELPAIH
ALELLDYSFPDPHARSFTIRCLRKLSDDELFQYLLQLVQVLKYESYLDCDLTCFLLERAL
ANKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSIFHIKSLIKGTALCCLKKALNDF
VKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKP
LWLMYKNKYDNVGIIFKNGDDLRQDMLTLQMIQLMDYTLLSNAALRMPVNWNKTGLIEVV
KNSDTIANIQRNNSNSAATAAFNKDEFTLSCAGYCVATYVLGIGDRHSDNIMISETGQLF
HIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILC
RNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWK
TKVNWMMHTFAKDNR
>A0A8C1ZZ64|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWVESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQNIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKRISEEKMQCMQLMSWGEWLRSCYSMTLEAGSLE
NLIDKHEGVIKITMHYDQSQDTSSLKVSLHCTVTELMDLALKKWQTTHVPEEDIGFRSDY
VLRVSRKLEFLFEDHHLNQCKYIRDCLLTNESPHLTLVHCDVVKAMFEKEISTIGSVLAW
KTSNPPLPLPPKKRLPTASTLFPALQLIKGVLSFIQVRAGLFHGTELLCKTAVSSESSSR
SEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHY
PIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFP
EYSTQPVVFPAFDKGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRHDCRENFPQSL
PKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVNCLRDMSDD
ELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMYMPAVSVHFAL
ILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFGTIKTKTKQAHLKEAMMTYLCVCRC
KYMDSKMKPLWIVYNNKLLGGDTVDIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRI
VPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDK
AIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERV
PFILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELT
SVKDIQYLKKDFLKNYYFCLLLTQSYHMASKELKYLFCCISTC
>A0A8C1X176|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
CCYNPEELYQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQT
YPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDS
KIGVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLETES
VENLIDKHEGVIKITMHYDQSQVCSVILALKKWQTTHGPEEDIGTRSDYVLRVSCRLEFL
LEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAIFEKEICTIGSVLARKASNPPLPLPP
KKRTPTVRTLSVFPALQLIKGALSFVPLAVRAGLFHGTELLCKTAVSSESSSRSEHVWNK
TLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHYPIAWVNT
MVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPV
VFPAFDKILEKAAEIAGASDSMTIGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRY
DCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFA
VNCLRDMRNAEIDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLR
SEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKLGTIKTKTKQAH
LKEAMMTCLRQTGFIETLSNLHSPLNPNILLAGVHVERCKYMDSKMKPLWIVYHNKLLGG
DTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSA
DTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGI
GDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTE
KFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEA
LKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A670J806|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podarcis muralis|TrEMBL
MPPGIACPVEFWSKEANQSIQVDFLLPTGIYLTLSISCNASLNTIKQMVWHHAQFEPLFH
MLSGPESYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDALSDPEVNDFRTKMHQFCEERVTRRQQLSWKAWMEYSFPVQLEPSSSSLGR
KSPLQVPNKNIFVNVKFESGGESFTFQISPKEFPVTLMSYAVKKQATIFRHQRMNSPEEY
ALQVNGKCEYLYGNYPLYQFQYIRDCLHRGLLPHLTMVHSTSIMALWEEQTNGITHPSKA
SPKPPPVPKKKPNSISLWSLEQPYYIDLVQGSKVNADERMKLVVQAGLYHGHEMLCKMVS
SSEVNVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIA
WVNIMLFDYQDQLKTGECCLPMWSSFPDEKGELLNPTGTVRTNPNTESAAALVIRFPGIL
LYPVYYPSFEQIMEHGRNGQCPRYMSEDPEEKQQLKEILERRSHTELYEHEKDLVWKMRH
QVRDQYPGALAKLLVVTKWNKHEDVAQMIHLLQSWPELPVLNALELLDFNFPDRYVGSFT
VNSLKKLTDAELFQYLLQLVQVLKYESYLDCKLTTFLLDRALSNRKIGHFLFWHLRSEMH
VPSVALRFGLILEAYCRGSTHHMKSLMRQSEALNKMKALNGIVKLSALKNPKPQTKEFMH
TCLRQETYLEALSNLQSPLNPSVILAKVSVELCTFMDSKMKPLWIVFNNEEIGGTSNVGI
IFKNGDDLRQDMLTLQMIQLMDILWKKEGLDLRMTPYGCLSTGDKTGLIEVVMDSDTIAN
IQLNKSNMAATAAFNKDALLNWLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERF
REYCERAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEARKHFQ
LKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C6PJX0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius furzeri|TrEMBL
MPPGKYGMQEEWEKEGDQNILMDFLLPTGIFLKFPVPRNDTIKNIKKMVWRNAKTEALYC
GLGDPEGYVFTCINDTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNSHISSL
IGKGLHEFEAQKNHEVDEFRSKMRTFCEEKALERHNLPWQQWMEYSFPCDLEPCCSPPVH
GGTKSKHTKKLFINVKFEACDESFMLQQDPLDIPVALMKSALKKRATVFRSVRQEPEDYT
LQVSGRWEFIYGNHPLRQFKYIFSCLRNGQNPQLIMVHHSTISKYQEEQGQLCSQVGKIR
SQSRPPPLPMKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQKLDFDINVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKRADCPI
AWVNTMVFDYKDQLKTGEFILSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPPLDKVIPPENLLISALRLSIGSKEMVSLLRNWPDLPAIQALELLDYSFPDPA
VRSFTIRCLRKLSDNELLQYLIQLVQVLKYESYLDCDLTTFLLERLTAEETSTTSSCQKM
TVEDLKLCIRQESYMEALSNLMSPLNPSIILVELCADKCRFMDSKMKPLWMMYKNPSEHA
DMVGIIFKNGDDLRQDMLTLQMIHLMEDLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKHS
DTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGI
GDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSE
KFERFREYCEWAYKILCKNGTLFVNLFAMMKAAEWHSKTDKCLHVTG
>A0A2K6FPL9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Propithecus coquereli|TrEMBL
MELENYEQPVVLREDNGRRRRRMKPRSAVASLSPMELIPIEFVLPTSQRHSKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQIHLVQRRAPSEETQAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLSKKIANNCIFIIIHRSTTSQTIKVSAEDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDDVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKVSADTSGSESKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPSPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIENQQPGPGK
>A0A6G1S0U8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hypotaenidia okinawae|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSSELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRA
>A0A668TM21|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDSEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEITFTLYDMAVDL
FTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVL
TQDFLIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSF
DDIAYIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8C9ZI42|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLLSIKQQLFTEARKYPLYH
LLQEESSYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNLESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGRRFSGSLSVGL
>A0A8D0A8Y2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
VGLENDMTFFLFDQEPKALREDTRRRRRKKAIMSSSCTSMDQISVEFVLPTAARGGNNPD
TLLLEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQV
FQTLDCIRYWRGTKDVGRIQLAPRPQPSDESQQYQRYLNYLIGYDVTDVSNVHDDELEFT
RRKLLTPRRIQLADRDAKLYSMDPWVTRKPLPEHLLSKISNGHILVVIHIGTASQTIKVS
IDNTPAQVLVSFLAKTANKRSLLGIPDNMCEADFVLRVCGREEYLYGDKPLQDFNWIRQC
LKNGEEIHLVLEAPPDTDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWD
CNRKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLEF
NIKIKDLPKGARLNLQCFLKPNMTSSRKIKSRLLYYVNLLLIDHRSLLRQGEFILHMWKM
PEKSEESSSSINADKLTSATNPDKASAMAVAILLDKYCYPVVLPKSRDVGRDAATGCEEA
EGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVR
WGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVL
RYLLQLVQAVKFEPYHDSALVRFLLKTALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLL
EAYLRGCGEDMLQDFRKQVEMTEALQKVTREVKAMSADKCDITAQVVFQLRQKLETLQSS
GLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDD
LRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIETVKDATTIANIQQSVVG
STGAFKDEILCQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITES
GNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICRE
KGWMVQINWFVHLVLGIKQGVEKRST
>A0A8C9XB92|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMLLTLECLREATLITVKHELFKEARKYPLYN
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESCAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPCAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMTIIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQHCVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A3P9C6T0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Maylandia zebra|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKSIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRAFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKTKNIKKIFINVKFEASDESFMLQQDPHDLPLVLMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTVTKCQEEQGRMCNQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPCVPDEKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKYFKLKEFMDNKNYTEFFEDEKELLWKLRTEVRDHYPESLSKLLLITKWNK
REDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLRKLSDDELLHYLIQLVQ
VLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASVGLRFGLILEAYCRGNIH
HIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESYLEALSDLLSPLNPSIIL
SEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWK
KEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGN
FKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLF
AMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEALRESWKTKVNWMMHSL
AKDNRP
>H3AV31|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Latimeria chalumnae|TrEMBL
IMPPRPSSGELWGLHLMPPRILVDCCLPNGMIVTLECLREAPLLSIKHDLFREAKKYPLY
HLLQDESSYIFVGVTQEAEREEFYDETRRLCDLRLFQPILKVIEPVGNREEKILNREIGF
AIGMPICEFELVKDPEVQDFRRNILGICKEAMDLREANGPHSQALYVYPPNVESIPELPM
HIYSKLDKGRIIVTIWVIVSPTNDKQKYTLKIPHDCLPEQVIAEAIRKKTRSMHLSPEQL
KLCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYIRNCITIGRLPHLMLMSKDSLYSQLPA
NTFVMPSYARRSATSSYMSGDPLTKSLWAINSLLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDIVNTQRVPCSNPRWMEWLSYDMYLTDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTDMLVAGKMALNLWPVPHGLEDLLNPIGVAGSNPNKETPCLELEFSWF
SHTVKFPDPTQIEEHANWSMSRELGFNYCLVDMSNRLARDSSLLESETEQLQEKDFLWRH
RHYCVNVPETLPKLLLSVKWNSRDEVSQMYCLLKEWPLIKPELALELLDCNFPDPVVREF
ALKCLVKGLTDEKLSQYLIQLVQVLKYEQYLDNPLARLLIKKALTNQRIGHFFFWHLNLG
GVRSEMHSKTVSQRFGLLLESFCRGCGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQK
NSFTFAWKSMERSCLSPSLSLSPSHPPSPSLSLFLRLEECRIMSSAKRPLWLIWENPDIM
SELLFTNNEIIFKNGDDLRQDMLTLQIIRIMESIWQSQGLDLRMLPYGCLSIGDCVGLIE
VVKNSHTIMQIQCKGGLKGALQFNSNALHHWLKDKNKGEAFDVCVCVCVWLEGCDWCVCV
CVCLGAAGAPETNCFQKQGSFAVGRSQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISRGVQECTKTKDFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAY
LRKTLALDKSEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPLT
>A0A3P9BH63|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Maylandia zebra|TrEMBL
MAPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLTTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYSNTPHCAGTKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLKMCVQEYQGKYILKV
CGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMDFFTMPSYARRISTA
TPYMNGETATKNLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGIYHGGEQLCDNVNTL
RVPCSNPRLWNEWLTYDMYIPEVPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYT
HTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHYSSPVKFPDMSTIE
DHANWNISRELGFNYCHTGLSNRLARDNPLTDGDNEQLRQVCNRDPLSEITEQEKDFLWR
HRHDCINMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNFPDPMVRE
FAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKS
EMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLKQEKKDEAQKVQMK
FLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWENPDMMSELL
FQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRN
SHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRSCAGYCVATFILGI
GDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTK
TREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQ
EALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A6J2QWC7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cottoperca gobio|TrEMBL
MPPAMTDLLDIWAAHSPLAGHALAQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAL
SFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRLSEERMQQVQMMTCTEWLQACFSPQLEPP
AGTAITDGLNDRPVDLKVIIHFDQSQDSASLKVPSSCTPSELMEMAVKKWLTTHGPEEEA
WRGQHVLRVSHCLDFLCGDQPLIQYKYIRTCMQAKESPHLTLVHTSTVKLMFNKEISAIG
AVVSRKSSNPPLPLPPKRRVPTQVQTCVWEVSIPFKIVLVNGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSDSSGRSDHTWKDSTLEFDLSVCDLPRMTRLCFAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHSIVFPPFDKILEKAAEIAGETDCVHISRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRYDCIDNFPQSLPKLLLSVKWSKHEDMAQLEALLQI
WPRLSPRDALELLDFNYPDQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALMLEAYCRGSIPHIEVLKKQVEALS
KLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNILLSGI
NVERCRYMDSKMKPLWIVYNNKLMGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAN
LDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSG
DALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGYTEKFARFVHFRSAS
>A0A6P7K1H6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Parambassis ranga|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRKNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSPDLPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTAAPYMCNGETVIKSLWTINGTLRIKILCATYVNVNIRDIDKIYVRTG
IYHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEH
CPLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVSGSNPNKETPCLELEFDH
LSGPVKYPDMTTIEDHANWNISRELGFNYCHTGLPNRLARDNPLTDSDNEQLRQVCNRDP
LSEITEQEKDFLWRHRHDCINMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAM
ELLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLL
KQEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRIMSSAKRPL
WLNWVNPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8D2KC49|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Urocitellus parryii|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSLGA
GNASRVPSRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQLLVEQPEDY
TLQVNGRHEYLYGSYPLCQFQYICSCMHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKP
RTKPPPIPVKKPSSVSLWSLEQPFCIDLIQGSKVNADERMKLVVQAGLFHGNEMLCKTVS
SSEVSVCSEPVWRQRLEFDINVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIA
WANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGSVRSNPNTESAATLVICLPEVA
PHPVYYPALEKILELGRHGERGRATEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQ
ERFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKS
LRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPS
VALRFGLIMEAYFRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCM
RQETYLEALSHLQSPLDPSTLLAEVCSVEQCTFMDSKMKPLWIMYSSEEAGSAGSVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQ
LNQSNLAAMAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRG
YCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A4W3GLX0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMIVTLECLREATLVSVKHDLFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDHEVQDFRRNILSVCKEAVELRDVNGANSRALYVYPSNVESSPELPKH
ISNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCMPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQSKYILKVCGCDEYLLEKYPLSQYKYVKSCIILGRMPNLMLMTKDSLYTQLPLD
TFTIPSYARRISTATPYMNGEASAKFLWAINSVLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGDPLCDNVNTQRVPCSNPRWNEWLTYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTDTLVSSKMALNLWPVPHGMEDLLNPIGVTGSNPNKSNRIACDSNLTE
GDIEQLRSIGSRDPLSEITEQEKDFLWRHRHYSVNVPEILPKLLLSVKWNSRDEVAQMYC
LLKDWPPIKPEQAMELLDCNYPDPMVRDFAVKCLEKSLTDDKLSQYLIQLVQVLKYEQYL
DNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQ
VEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQGFMSPLNPAHQLGNLR
LEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQ
IQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKN
KGEGYDGAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKF
GYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEICYKAYLAIRQHANLFINLFSMM
LGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQH
TLN
>A0A6P7MZW9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Betta splendens|TrEMBL
MPPGKYGMPGEWEKEGDHEIMMDFLLPTGIFLTFPVSRNDTIKTIKKMVWKNARGEALFA
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMFVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEVKAQERQALPWQQWMEYRFPCDLEPCCSPQQC
GKSKGTKKILVNVKFEASDESFMLQQDPQDLPVALVKSALKKKATVFRSVRQEPEDYTLQ
VNGRWEFIYGKHPLCQFKYIFACLRNGQNPHLVMVHHSTIRKHQEEQGRMCNQAYKSCSL
SRPPPLPLKKNTSSLWSINEPFCIHLMQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSS
EVTVCCEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWV
NTMVFDYKDQLKTGEVLLSTWPSVPDDKSDLLNPMGTVERNPNVDSAAGLLIRFAHVRPY
PLYYPPLDKMSDTERNGDASFATNEEYSKLKEIMDNKNYTEFFEDEKELLWKLRCEVRSR
YPESLSKLLLITKWNKREDVVQMVSLLRNWPVLPAIHALELLDYSFPDPAVRSFTIRCLR
NLSDDELLQYLIQLVQVLKYESYLDCDLTMFLLERALSNRKIGHFLFWHLRSEIHVASVS
LRFGLILEAYCRGNIHHIKFLTKQNEALGKMKSLSDFVKSGSQKMTVEDLKLCIKQESYL
EALSDLLSPLNPSIVLSEICADKCRFMDSKMKPLWLMYRNPGSQGNMVGIIFKNGDDLRQ
DMLTLQMIQLMENLWKREGLDLRMSPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAA
TAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQ
LFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCELAYKI
LCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLSLGKSEEEALKNFKVKFNEALRES
WKTKVNWMMHSLAKDNRP
>A0A6P7N9S5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Betta splendens|TrEMBL
MDRRRILVSVEKPVVLREVIRRRKKAISSSSSTSMDQITVEFVLPTATWGGNPDSLQLEV
AGNWTVEQVKAQVWLKAVTSNFCPEFYQRFCPDYCILLYQKKGNLCEIYDKHQVFQTLDC
IRYWRALKKEVGKIQMVPRPQPSEESLHYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLL
TPRRIELCDRDPKLYSMDPWATHKPVPEHLLNKVTNGHILVVIHMSTASQTIKVSVDDTP
AQVLTNFFNKIANKRVLLGIPDNVCDADYVLRVCGREEYLYGEKPLQSFNWIRQCLKNGE
EIHLVLETPPDPELDLVMKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKF
RVKVLGIDIPTLPKVPEFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKIK
DLPKGARLNLQVVCGKQPQTPNSKGVFYQDYTSGGCIDGKTKSRLLYYVNLLLIDHRSLL
RQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKESSMAVAILLDKYCYPVVLPKSRD
VCRDAGVAGEEAELGERGQREMPNHLKKQFEAIVATDPLHPLSPEDKELLWHFRHECMRD
PRAYPKLLGSVKWGKQEDVLAIHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAV
RKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQ
SMHYQQRYAVLLEAYLRGCGEAMLQDFRKQVEMTEALQKVTREIKAVSADKYDVTAQVVF
QLRQKLETLQLSGLPESFRVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSK
DPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDA
TTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIG
DRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPH
FQKFQDVCIKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQ
RHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A3B4EDL5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pygocentrus nattereri|TrEMBL
MPPGVYYGMQDVWEKEGREQVNMEFLLPTGIYLSFPVARSDTIGMVWKHARSEPLFNVLS
DPDAYVFTCINRTAEREELEDEQRRLCDVQPFMPVLRLVAREGDRVEKLINTQISLLLGK
GLHEFDAQKNHEVAEFRTKMRSFCEEKAQDRQRLPWHQWMEYNFPCDLEPFSRAAQSGKS
RSVKKIFINVKFEASEESFMLQLDPQDMPVVLMRSALKKKATVFRPVKQEKPEDYTLQVN
GRWEFIYGKNPLCQFKYIFSCLYGGQTPHLTMVHHSTITKYQEEQGTLSSQVSKSRSLSK
PPPLPLKKLVVQAGLFHGSELLCKVVTSSEVSVCSDPVWDQKLAFEINLCDLPRMSRLCF
ALYGVLEKTKKQRSTKKKKKADCPLAWVNTMVFDYKDQLKTGEFLLSTWPSAPDDKGDLL
NPMGTVERNPNIDSTAGLLIRFSNFRPHPLCYPPLEKLLTTCTIHSRCGISHCCAQHQKL
KEIVDNKNHTEFFEDEKELLWKLRGEVRAHYPESLSKLLLITKWNKHEDVAQMVCLLRKW
PDLPALHALELLDYSFPDPHVRSFTIRCLRKLRDDELFQYLLQLVQVLKYESYLDCDLTT
FLLERALSNKKIGHFLYWHLRSEMHVSSVSLRFGLILEAYCRGSIYHIKSLMKQNEALNK
MKALNDFVKSGSQKSTSRSQITEDMKLCIKQDTYVEALSDTVSPLNPNIILSDICTEKCK
FMDSKMKPLWLMYKNKWVQADTVGIIFKNGDDLRQDMLTLQMIQLMDILWKTEGLDLRDK
LDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKAKFGINR
ERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMRAAGLP
ELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMVHTFAKDNR
>A0A8D2J434|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Varanus komodoensis|TrEMBL
MTLGIYCPVEFWSKEANQSIQVDFLLPTGIYLTLPVSCNVTLGAIKQVVWHHAQYEPLFQ
MLSDPDSYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLVNSQISLL
IGKGLHEFDSLKDPEVNDFRAQMLQFCEERVARRQQLNWRAWMEYSFPVQLEPVANGLGR
SPLPVPSKNIFVNVKFESGGESFTFQISPKDFPTTLMSYAIKKQATIFRHQRVSSPDDYT
LQINGKYEYLYGNHPLHQFQYIRDCLHRGLLPHLTMVHSSSILALWEEQTNGITAPPKGS
TKPPPVPKKKVSSVSLWSLEQPYYIELVQGSKVNADERMKLVVQAGLYHGHEMLCKMMSS
SEVAVSSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYRDQLKTGECCLPMWSSFPDEKGELLNPMGTVQTNPNTESAAALVIRFPEISF
CPVYYPTFEQVGRGLHPIIAPKQQLKEILERRTHTELYEHEKDLLWKMRHQIRDQYPGAL
AKLLLVTKWNKHEDVAQMIYLLQSWPELPVLNALELLDFSFPDRYLSAFTVNSLKKMTEA
ELFQYLLQLVQVLKYESYLDCELTRLLLDRAFSNRKIGHFLFWHLRSEMHVPTVALKFGL
ILEAYCRGSIHHMKALMKQTDALTKMKGLNDIIKVSAQKNPKPQTKESMHTCLRQETYLE
ALSHLESPLNPSIILAKVNVEMCTFMDSKMKPLWLVFSNEETGGDSVGLIFKNGDDLRQD
MLTLQMIQLMDILWKKEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAAT
AAFNKDALLNWLKSKNPGDALERAIEEFTLSCAGYCVATYVLGVGDRHSDNIMIRENGQL
FHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQEGKTNNSEKFERFREYCETAYMIL
RCHGLLFLHLFALMKAAGLPELSCSKDIQYLKVRGLRGPWTPHFSNLTLPWGTPPTLI
>A0A8C5SGE7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Laticauda laticaudata|TrEMBL
MPGMPPGMYCPSEFWSKESNYTIHVDFLLPTGIYLPLPVSCHASLAAIKKVVWHQAQYEP
FFQMLSAPDSYVFTCINQAAELQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLLNSQI
SLLIGKGLHEFDSLADAEVNDFRVQMRDYCEQRAAQRQQLNWKDWMEYSFPVQLEPALSG
LRRRPSLPMPGKTIFVNVKFQSGGESFTFQISLKEFPITLMSYAVKKQATIFRHQRVSSA
DEYTLQVNGKYEYIYGEYPLYQFQYIRECLHRRFVPHLIMIHRSSLLTLREEQSNGLGHP
PKTALKLSPGPKQKLTCVSLWSLDQPYYIELLHCSKVNANEGMKLVVQAGLYHGHEMLCK
MMTSTEANVCSEPTWDQTLKFDIHVWDLPRMARLCLALYSVVEKAKKARSTKKKSKKADC
PLAWVNVMLFDYQDQLKAGECILPMWSAFPDEKGELLNPMGTIQTNPNAESAATLFIRFP
GISLYPIYYPSTRQILEKGQNGHCACGTEEDPEEKQQLKEILERRSCIELYEHEKDLVWK
MRYQIRDQYPGALAKLLMVTKWNKHEDVAQMIFLLQSWPELPILNALELLDFNFPDPHVS
HFTVNSLKKLTDAELFQYLLQLVQVLKYQSYLDCELTKFLLGRALSNRKVGHFLFWHLRS
EMHFPSLALRFGLILEAYCRGNADHIKALMKQSEALNKLKALNDLIKVSAQKNTKPQTKE
FMHTCMRQETYLEALSHLQSPLDPRIFLARVSVELCTVMDSKMKPLWIMFNNGEAGGHST
GLIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKMGLIEVVMNSDTI
ANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDR
HSDNIMVRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFE
RFRDYCERAYMILRGHGLLFLHLFSLMKAAGLPELSCSKDIQYLKDSLALGKTDEEARKQ
FHLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P7WTA3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcaecilia unicolor|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCIPNGMIVTLECLREATLLGIKHNLFKEARKYPLFH
LLQDESSYIFVGVTQEAEREEFYDETRRLCDLRLFQPILKVIEPVGNREEKILNREIGFA
IGMPICEFEMVKDPEVQEFRRNILSVCKEAMDLREASGSHSQALYVYPPNVESTPELPKH
IYNKLDKGLIIVTIWVIVFPNNDKQKYTLKIPHDCLPEQVIADAIRKKTRSMHLSPEQLK
LCVQEYQGKYILKVCGCDEYLLEKYPFSQYKYIRNCITIGRLPHLMLMSKESLYSQLPAN
IFIMPSYARRSVTSCYMNGDVPTKSLWSINSLLRIRILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYLTDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINLFDYKDTLVAGKMALNLWPVPHGLEDLLNPIGVGGSNPNKETPCLELEFSWYT
HAVKFPDTPQIEEHANWSMSRELGLNYCLVGLSNRLARDSSLIENEMEQLRNICNRDPLS
EITEQEKDFLWRHRQYCINIPETLPKLLLSVKWNSRDEVTQMYCLLREWPLIKPELSLEL
LDCNFPDPMVREFALKCLVKGLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLIKKALTNQ
RIGHFFFWHLKSEMHSKTVSQRFGLMLEAFCRGCGMYLKHLNRQVEAMEKLINLTDILKQ
EKKDETQKMQMKFLMEQMRRPAYMEALQGFICPLNPVHQLGNLRLEECRIMSSAKRPLWL
NWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIRIMENMWQNQGQDLRMLPYGCLSI
GDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWLKDKNKGEGYDAAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGVQECTKTKEFERFQEMCYKAYLVIRQQANLFINLFSMMLGSGMPELQSFDDIAY
LRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPLSEAGHD
>A0A7L2R276|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oxylabes madagascariensis|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEILLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRT
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPVALPKHRISSE
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESVKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQ
>A0A7L3N9L6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreotrochilus melanogaster|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWSAWMEYNFPLQLEPMAKRLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVESPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQNNCIASPPKMA
HKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRMDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAAEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNRHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8D2NZM9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zosterops lateralis melanops|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEILLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A094L7M2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Antrostomus carolinensis|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLLEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIHSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAVEA
AINRKSSNLPLPLPPKKTRTTTSVWDISSPFKIILMKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNQ
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELILHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSIKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C9F6F4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pavo cristatus|TrEMBL
QLNNNIPFKDPLVKDTLIDNELCSKLLWKQAHTYPLFHLLMEIDSYMFSCVNQTAVHEEL
EDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKIGVLIGKGLHEFDALQDPEVNDFRSKM
RRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPENFQDKLYSGNLVVAVHFDNCQDVFSF
QVSPNMNPIKLNELAIRKRLTIHGKEDEEIDPADYVLQVSGRLEYVFGDHPLIQFQYIHN
CVMNRTLPQLTLVECCTIKKMCEQEMIAIEVAINRKSSNLPLPLPPKKTRATTVILLKIY
PSWISSLKCNKNGSFHETFNKCFNGLLYQIVFLSSYFNCNLIVFFLKQLQALLQIWPKLL
PREALELLDFNYPDQYVREYAVGCLKQMRLRDLEHDEELSQYLLQLVQVLKYEPFLDCAL
SRFLLERALANRRIGQMLFWHLRSEIHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEAL
NKMKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKC
KYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRI
LPYGCLATGDHSGLIEAVSGSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDR
ATEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERV
PFILTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELT
SVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C9FTR3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pavo cristatus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELITIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAIEVSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDLFPLVLSLLDCRALHMLLTRLLCIFQAVKFEPYH
DSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLHDFM
KQVQVIELLHKVTMEIKSVSAEKYDVTSQETQPYPRQEKCKVMASKKKPLWLEFKCADPT
ALSNETIGIIFKHGDDLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEI
VKDATTIAKIQQSTVGNTGAFKDEILNQWLKDRCVIEEKFQAAVERFVYSCAGYCVATFV
LGIGDRHNDNIMITETGESGSVTIAFKFRYFYDIETYHYPFWAFM
>A0A8C5TQJ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Malurus cyaneus samueli|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SIQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRTCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDICNPFKIVLLKGNKLNTEENAKVHVRAGLFHGTELLC
KTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNTSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A4W4HHF2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MPPGVCYGMQDVWEKGGREQVTLEFLLPTGIYLSFPVARNDTIGTIKKMVWKNARSEPLF
SVLSDPDAYVFTCINLTAEREELEDESRRLCDVRPFMPVLRLVAREGDRVEKLINTQISL
LIGKGLHEFDTQKNHEVNEFRAKMRSFCEENAQDRQRLPWHQWMKCNFPCDLEPFSMVVQ
SGKSCSVKKLLVNVKFEASEESFMLQLDPQDFPVVLMQNALRKKATVFRPLKQEKPENYT
LQVNGRWQFIYGNSPLCQFKYIFSCLYGGIKPHLTMVHHSTIIKYQEEQGGLSNQVSKSR
SLSKPPPLPLKKQNTSSLWSIKEPFFIQLVHGTRVNTDEGMKLVVQAGLFHGGELLCKVV
TSSEVSVCSDPVWDQKLVFDINLCDLPRMSRLCFTLYGVLEKTKKQRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSAPDDKGDLLNPMGTVERNPNIDSTAGLLIRFPSF
RPHPLYYPPLEKVNRTASHLKLKEIVDNKNHTEFFEHEKELLWKLRLDVRAHYPESLSKL
LLITKWNKHEDVAQMVCLLRTWRDLPPLHALELLDYTFPDPHVRSFTIRCLKKLGDEELF
QYLLQLVQVLKYESYLDCDLTTFLLERALSNKKIGHFLFWHLRSEMHVASVSLRFGLILE
AYCRGSIYHIKSLMKQIEALNKMKALNDFVKSGSQKSASRLQITEDMKLCIKQDTYMEAL
SDVISPLSPSIVLSEICPDRCKFMDSKMKPLWLMYKNKWDHLDTVGIIFKNGDDLRQDML
TLQMIQLMDVLWKTEGLDLRMVPYGCLSTGNKTGLIEVVKNADTIANIQRNSSNNAATAA
FNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFH
IDFGHFLGNFKAKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCR
NGTLFVNLFALMRAAGLPELSCSKDIQYLKDSLALGRSEEEALKNFKVKFNEALRESWKT
KVNWMMHTVAKDNR
>A0A2K6DNW0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca nemestrina|TrEMBL
MELENYEQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSMASDFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPAVSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDTCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A024R4H1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSAQTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREIPGAAGVLGSCMSTRRTWCGSCGMKSR
STSRRR
>A0A8C8J1B5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRVKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQLSKS
RSLSKPPPLPVKKQNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKV
VTSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCP
LAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIHFPN
IRPHPLYYPHFDKLRDLEKNGGKVIATKVEHMKLKEIVDNKNYTEFFEDEKELLWKLRGV
VRERYPESLSKLLLITKWNKHEDVAQMVTFLQKWPDLPALHALELLDYSFPDPMVRSFTI
RCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHV
SSVSLRFGLILEAYCRGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKL
CIKQEAYMEALSYLLSPLNPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDTVGIIF
KNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQ
RNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDN
IMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRE
CCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVK
FNEALRESWKTKVNWMMHSLAKDSRL
>A0A5K1UPW2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPGVDCPMEFWTKEENQSVDVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSDPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNRHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYAILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C2AAM4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVAQS
GKSRSVKKILVNVKFEGSEETFVLQQDPQDLPMLLKRNALRKKSTVFRAAKQEKPEDYTL
QVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQMSRTRA
PSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNETKKRPTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGT
VEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKLNELGMNGEKVVTTKEEHMKLREIVDNK
NYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIH
ALELLDYSFPDPHVRSFTIRCLRNLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLKRAL
ANKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDF
VKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCTDKCKFMDSKMKP
LWLMYKNKYDHVGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKT
GLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGY
CVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVI
QEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSL
ALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A4W2DY00|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos indicus x Bos taurus|TrEMBL
MCFYFMMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISCIKQMLW
KQVTNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPEL
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHSLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMVAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEPLEFDINTCDLPRMTRLCFAVYAVLDKVKTKKSTKTM
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPHALPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKTEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>K7BQ68|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan troglodytes|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A1A8FID8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius korthausae|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREAALNTIKHELFKEVRKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDSSGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYTQLPTD
CFVMPSYSRRISTATSYMNGEAASKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSVCSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVASKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWIISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNFPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNELIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSPECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A3Q7QJH9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinus ursinus|TrEMBL
MSGMELKHHEQPVVLREDNGRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRNSKTPETA
LLHVAGHGNVEQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQ
TLDCLRYWQVLHRSPGQIHVVQRRAPSEETLAFQRQLTALIGYDVTDVSNVHDNELEFTR
RRLVTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSA
DDTPGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCL
KNGEEIHLVLDSPPDPALDEVRREEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDC
DRKFRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFS
IKIKDLPRGALLNLQIYCSKAPALSGKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRH
GEYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPD
PEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVK
WGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVIL
EAYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNS
NLPESFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLYFQKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGEKHSA
>A0A3Q7Q5C3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinus ursinus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECFKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVDCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVGKLIFQV
EALNKLKTLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYV
EKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLD
LRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDD
LDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKR
ERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLP
ELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A2I4C1N4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Austrofundulus limnaeus|TrEMBL
MDRQQIQVSDEEREVPREENRRRRRKKAITSSSSASMDQITVEFVLPTAARGGNGSDSLL
LEVAGNWTVEQVKAQVWMKAVTLNLCPEFYQRFSPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPTDESLQYQRYLNYLIGYDATDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWATRKPLPEHLLSKVNNGYILVVIHVSTSSQTIKVSID
DTPSQVLANFFAKTANKRVLLGIPDNVCEVDFVLRVCGREEYLYGEKPLQNFNWIRQCLK
NGEEIHLVLEMPLDPELDMVQKEDWAQVDDCTGVAGTHEQLTIAEKDHERVFTISMWDCN
RKFRVKVLGIDIPTLPKVPDFTVFVEASIFHGQQLLAQERTTSKSFNEEVLWNCWLEFNI
KIRDLPKGARLNLQVICGKQPQLLNSKGGFYHDNTSGTGSLDGKTKNRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAVAILLDKYCYPVVLP
KSRDVGRDCGARGEEEAEGGERGQREMPNHLKKQFEAIVSTDXLHPLSPEDKELLWHFRH
ECMRDPRAYPKLLGSVRWGKQEDVLAMHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQV
RSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLR
SEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRKQVEMTEALQKVAREVKAMSADKYDVT
AQVVFQLRQKLETLQTSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADP
TTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIE
IVKDATTIANIQQSVVGSTGAFKDEILHQWLRDKCVSEDKFQQAVERFLYSCGGYCVATY
VLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGK
KSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRS
EEEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A6J2MTV2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phyllostomus discolor|TrEMBL
MELENNEQPVVLREDNCRRRRRMKPRGSAASLSSMELIPIEFVLPTSQRTSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVVADFYHRLSPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHSPSEESLAFQRLLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPAQDEVKKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQVYCGKAPALSGKASADIPSSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSICILLDNYCHPIALPKHRPTPDPEG
DRIRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLSRREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRALRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGAAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVILQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSKETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCAKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7J8DDH2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Molossus molossus|TrEMBL
MCFNFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISSIKKMLW
TQIHNYPMFNLLMEIDSYRFACVNQTAVYEELEDETRRLCDVRPFLPVLKVVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWIDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQISGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAISRNSSNLPLPLPPKKRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGT
ELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTIN
ASKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQT
NPYTENATALHIKFPENKKQPYYYPPFDKYEAACLGIRRVSLGNLKHSSILSSGLASLFQ
IIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQDCRENFP
QSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQM
SKRIQSRIGKGKRFMGQSLEETSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANR
RIGQFLFWHLRSEVHIPAISIQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKL
NAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYIEKCKYMDSKMKPLWL
VYNNQVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRS
GLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGY
CVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVI
QQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSL
ALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A671T346|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPAKTDQLDLWAESGLDGDVQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSCGEWLRSCYSTQLGTGSLE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDY
VLRVSGRFEFLFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLAR
KTSNPPLPLPPKKRPPTVSTLSVFPALQLIKGVPSFVHLAAPNSNAKVRAGLFHGTELLC
KTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKY
QTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYT
ENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMERD
PLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRD
ALELLDFNYPDQYVREFAVICLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQ
SSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVSEL
IKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLQSPLNPNILLAGVHVERCKYMDSKM
KPLWIVYNNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLA
TGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTL
SCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHD
FIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A671TAD6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPGVYGMQDVWEREGWQQVNMEFLLPTGIYLNFPVTCSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVCQMLPWDQWMEYNFPCDLEPCSVVAQS
GKSCSDKKIFVNVKFEGSEETFVLQQGPQDLPMFLKRNALRKKSTVFRSAKQEKPEDYAL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLEFDISVSDLPRMSRLCIALYGVIEKTKKRPTKKKNKSSDCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGMNGEKTVATKEEHLKLREIVDNKNYTEFFEDEKELLWKLREEVRQ
RYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHARSFTIRCL
RKLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVSSV
SLRFGLILEAFCRGSIFHIKNLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIK
QDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDTLGIIFKNGDDL
RQDMLTLQMIQLMDVLWKTEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECC
EQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFN
EALRESWKTKVNWMMHTFAKDNR
>A0A7K7KWS2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Asarcornis scutulata|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GLLHTPTKNIFVNVKFQSGGESFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANTPKMS
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNIESAASLVICFPNVAS
HPVYYPSFEQLLELGRNGEPPRTAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDNELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6J0WFP7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Odocoileus virginianus texanus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A672UTJ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
TRDRSTFHPAVALAQVVWKHAQYEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDI
QPFLPVLRLVAREGDRVKKVINSQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAA
KRQQLSWAAWMEYNFPLQLEPMAKALCWCLTVYAVLLGLQESFTFQISPNEFPITLMSYA
IKKQATVFRHETLEKPEDYTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSS
TIIAMRDEQTNCITSPPKTATKPPPLPKKKVKGGSDPAGSTSNHPLMEMLSLCGNNTGLF
HGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTK
KKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESA
AALVICFPSVASHPVYYPSFEQVGTFPTLSYDSHEQKLQLKEILERRSHTELYEHEKDLV
WKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRY
VGSFAVNSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHL
RSEMHVPAVALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQT
KEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGG
GVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSD
TIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIG
DRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEK
FERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEAL
KHFRLKFNEALRESWKTKVNWLAHNVSKNNRQ
>A0A8C7F0Q1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MEQQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPTEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKHLPEYLLFCIGHILLVIHRNKASQTIKVSIDD
TPVQALQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCLKN
GEEIHLVLESALNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDCHR
KFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFNIR
IRDLPKGARLSLQDNGGSPVGGGSGNHDCNKTKSRLLYYVNLLLVDHRSLLRQGEFILHM
WKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYPVALPKSREGKEAGGEGRE
AEGGERGQREMPNHLRKQFEAIVETDPLHPLSQEDKELLWHFREECMRHPRAYPKLLGSV
RWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLETLGNDDV
LRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVL
LEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQVVFQLRQKLENLQT
SGLPESFRVPYDPGLRAGALVVKQCKVMASKKRPLWLQFKRADPTTLSSDTIGVIFKDGD
DLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSVV
GSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLGVGDRHNDNIMITE
SGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVRA
YLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEEAQRHLLDQIEICR
DKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A7K4V9Y0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Emberiza fucata|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPATKSLSS
LQIPTKNIFVNIRFQSGGESFMFQISPREFPITLMSYAIKKQATVLRPETVQQPQDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLVITKWNKHEDVAQIISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C6BRT7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodon monoceros|TrEMBL
MELENHEQHVVLREDNRRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLSPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRLAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDTKLYAMHPWVTSKPLPEYLLKKITNNYIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIRNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKAEDHGSINADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCSFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTMDIKSLSAEKYDVSSQVISQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSRHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8C7IVK3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPRPSSGELWGMHLMPPSIQVDCLLPNGMILTLVCTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANCNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCGTIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>F6RS48|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callithrix jacchus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLNGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRTKMCQFCEEAAARRQQLSWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRSKPPPIPAKKPSSVSLWSLDQPFCIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDISISDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLHMWPSVPDEKGELLNP
TGTVRSNPNSDSAAALLICLPEVAPYPVYYPPLEKLLGGMLLASGRWRPELLWLSLHARD
SAPSRMIGVEMPCLGIPPGLVQAPEDTEGSCLLQILELGRHSECVRVTEEEQLQLREILE
RRGCGELYEHEKDLLWKLRHEVQERFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPV
LGALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDR
ALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSSGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C4FWS1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPTMMDVLDLWAELGEVEHVSVDFLLPTGLYIQMEVPREATIQHIKQLLWKEAAGYPLF
TLLGAMEGHMFECVNQTAVHEELEDETRRLCDVRPFLPVLRVVTRSGGHNERLLDSKIGV
LIGKGLHELDSLQDQEIKDFRTKMQQISKEKIQRIQVMSWEEWLRTHFSPQLEVGQVDGM
IEKLCEDGIKVTMHYDQSQVCTVRTLLELALRKWANTHGHNNSSCLSDYILRISSKLEIL
YYVLGICLIFVCVQYIRECLLAQESPHLTVMHSSVLRGIDETKIIRRVVQKPRSTCTQFF
KRKQAGLFHGAELLGKPAVSSDSSGRLEHLWNTTLEFDVAVSDLPRMSRLCFAIYAVMDK
VKKQPKSIKTPHSKYQTIRKHYPIAWVNTMVFDYKGLLKTGDVVLYCWSSFPDELEEMLN
PIGTVQTNPYTENATAIHITFPEYSQISVIFPPFDKRLSPHGSECLHHSYNKDSLKEIMD
REPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWNKHEDMAQLQALLQIWPTLSH
RDALELLDFNYPDQYVREYAVNCLRDMSDEELSQYLLQLVQVLRYEPYYDCALSRFLLER
SQLNRNIGHFLFWHLRSEMHMPAVSVQFALILEAYCRSSIPHIEVLKKQVEALNKLKAVN
ALVKTGAVKSKARTKDSHLKEAMLTCLRQSGFTETLSDIHSPLNPSVLLAEVNVDRCKYM
DSKMKPLWIVYNNKLLGGETLGIIFKNGDDLRQDMLTLQILKLMDLLWKEANLDLRIVPY
GCLATGDHSGLIEVVSSADTIANILKTSSNMAATAAFNKDALLNWLKEKNSGDTLERAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFI
LTHDFIHVIQQGKTANTEKFGSFRQYCEEAYLVLRRNGNLIITLFALMLTAGLPELTSVK
DIQYLKDSLALGKSEEEALKQFRQKFDEALRESWTTKVNWMAHHIAHAS
>A0A3P9K9H8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MKIAELWFVCRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHHLLQEETCY
IFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEF
DLVKDFEVQDFRRNILNVCKDAVELRDANGPHSRALYVYPPNVESSQELPKHIYSKLDKG
QIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQG
KYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYSQLPTDSFVMPSYC
RRISTATSYMNGEAAPKSLWTISGGLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQMC
DNVNTQRVPCSNPRWNEWLNYDMYILDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNIN
LFDYNHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEHFSSPVKYPD
MNAVEEHANWTISRELGFNYNTSGQSNRVARDHALTDSDSEQLKQLSNRDPLSEITEQEK
DFLWRYRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAMELLDCNYPD
PMVRHFAVRCLDKFLADDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFF
WHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQ
KVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDI
MSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLI
EVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNRGEMYDMAVDLFTRSCAGYCVAT
FILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGS
QECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLAL
EKGEQVSRHFTGNQNLRSFETSPHQLKRLFHVAGSIGLLYETDERCSPWRVDHQDGLDIP
HN
>A0A8B7AG66|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Orycteropus afer afer|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKISHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYEIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKIALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFNYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8B7AE08|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Orycteropus afer afer|TrEMBL
MCFNFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISHIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMHQFSEEKIQSLIGLSWMDWLTQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIILVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVLLHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C4S1E2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Erpetoichthys calabaricus|TrEMBL
MPPGMYFILENWEEEASQDVQIDFLLPTGIYLSLSVSRNSTIEAIKEIIWNKAKTEPLFC
ALNDPDNYVFMCINHTAEREEIEDEQRRLCDVRPFFCVLQLVGREGNRIEKQINSQISLL
IGKGLHEFHSLKNLEVNDFRTKIRPFCEEKAMDRQRLTWYPWMMCNYPFELEPYPKLPET
GVLKSRSSKKFMVNVKFENSEESFTLQISPQDVPLTLMQSALKKRAMVFREPKQDKVTDY
VLKVNGRLEFIYGDYPLYQFKFICACLHASTTPHLTMIHCSTIKSMQDEQEGFSVQVSKI
CSGPKRPPLPPKKQDMSFTIEEPFQIHLLQASKVNVDDGMTDCPLSWVNTMVFDYADRLK
TGELTLYAWPSTLDDKVDLLNPMGTVDSNPNIESTVSLTIFFPNFRTQPIYYPPTEKIIQ
MGMNGKASRASPEELQKLKEVLENKNYTEFFEDDKELLWKLRYDIRELYPENLAKLLSIT
KWNKQEDVAEMIYLLQHWPDLSPLHALELLDYTFPDRSVRAFTIRCLRKLSDDELFQYLL
QLVQVLKYESYLDGDLTRFLLERALANRKIGHFLFWHLRSEMHVPSVSFRFGLILEAYCR
GSTPHMKILAKQNEALNKMKSLTDFVKSSSQKTTKNITKEVMQFYMKQDAYLEALKDLLN
PLNPNLILSDLCVEKCKFMDSKMKPLWLVYNDSFQSGSIGIIFKNGDDLRQDMLTLQMIK
LMDVLWKQEGLDLRMIPYGCLSTGYKTGLIEVVIDSDTIANIQLNKSNMAATAAFNKDAL
LNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRQNGQLFHIDFGHF
LGNFKSKFGINRERVPFILTYDFVHVIQQGRTNDSEKFERFRSYCETAYKILCRNGVLFV
NLFKIMQASGLPELSSSKDIQYLKDSLALGKPEEEALKNFKVKFNEALRESWKTKVNWMA
HNVAKDNR
>A0A2I0LW23|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Columba livia|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRKISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYNGNIVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKDDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAVEAAIH
RKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMTGRGGKKFYIVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNIEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8J4MJI3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Spheniscus mendiculus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCMSGNLSSMELISIEFILPTSNKHTKVPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQKRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGNRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEVVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K8PF07|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cochlearius cochlearius|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GSLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRTGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDHYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C3TWN8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Catharus ustulatus|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKSMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLRSGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPVNYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLREDLDRAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A1A8JDT7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius kuhntae|TrEMBL
MDRQQIQVSDEECEVPREEIRRRRRKKAITSSSSISMDQITVEFVLPSAARGGSSSDSLQ
LEVAGNWTVEQVKAQLWMKAVTLNFCPDFFQRLSPDHCILLYQKKGTICEIYDKHQVFQT
LDCIRYWRALKKEVGRIQLVPRPQPTDESLQYQRYLNHLIGYDVTDVSNVHDDELEFTRR
KLLTPRRVELSDRDPKLYSMDPWVTHKQLPEHLLTKVNNGYILVVIHVSTSSQTIKVSID
DTPSQVLTSFFAKTQNKRVLLGIPDNMCESDFVLRVCGREEYLYGERPLQDFNWIRQCLK
GGEEIHLVLETPPDPELDLVQKEDWAQVDDCTGVTGTHEQLTITEKDHERVFTISMWDCN
RKFRMKVLGIDIPTLPKVPDFTVFVEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGTRLNLQVICGKQPQMSSSRGGSYYEATSGTCCPEGKTKNRVLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAVAISLDKYCYPVVLP
KSRDVGRDCGAMGEESEGGERGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRHE
CMRHPRAYPKLLGSVRWGKQEDVLSTHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVR
SIAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTREVKTMSADKCDITA
QVVFQLRQKLETLQLSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPT
TLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKK
SSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSE
DEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A673LJ58|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
ILKAGVDGVLDDEPPVVRREENKRRRRKMKAFTSTSAVSTDHIAVEFVLPTTNKNSRNPD
TLHIDVTGNWTVEQVKVQIWHRAVTTKLYLKTLLASVFVLLTSKQLWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVVRTQPTEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDPKLYSMDPWMTTKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFAKITNKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKN
GEEIHLVLERPPDPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDQYCYPVALPKSKDSPDSEMEGERG
QREMPNHMRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEA
VTITHRLLERSTVWDRSSLDVGLALQLMDCHFSDENVRTMAVRKLETLAGDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRG
CGEAMLQDFRKQVEMTEALHKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDSF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFMGISKERVPFVLTPDFLYVMSTTGKKSSPHFLQFQSVCLKAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQ
FNWFLHLVLGIKQGVEKRSA
>M7BT09|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelonia mydas|TrEMBL
MELRNYEQPVVMREENKRRRRRMKPYSAASNLSSMELISIEFILPTNNKHTKMSETMLLE
IAGNCTVEQMKAQIWLRAIEMSQTTDFYHKFTPDQFILQYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGKIHVVQKEKPTEAVQEFQTQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYSMHPWITSKPLPEYVFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDDPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFIISLWDCNRK
FRVKIVGIDIPVLPRNTELTVFVEANIQHGQQLLSQRRTTSKPFTEEVLWNTWVEFDIKI
KDLPKGALLNLQIYCGKAQALSTKVSLQSHDSPNSDSKCKTQLLYYVNILLIDHRSLLRS
GEYVLHMWKISGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEAIVDTDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKREAWDHSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQIIKLLHKVTMDIKSVSAEKYDVTSQGMIEIVKDATTIAKI
QQSTVGNTGAFKDEILNQWLKDRCVIEEKDICVKAYLALRHHTNLLIILFSMMLMTGMPQ
LTSKEDIEYIRDALTVGKNEEDAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKH
SA
>A0A850UPY2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chloropsis hardwickii|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWVAWMEYNFPLQLEPVAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
CKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K5D751|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pachyramphus minor|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCASSSFSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPILPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDTKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K8LYU2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ptilorrhoa leucosticta|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSERDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
DEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNNDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSSSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKEKCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C3DZX8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Corvus moneduloides|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSVSVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTTVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQCGFPEVSLYNSALQKCSVWNPGPAPCCALRTW
LFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLI
LRKHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRES
WTTKVNWMAHTVRKDYRS
>U3JXY4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ficedula albicollis|TrEMBL
MPPGIYCPSEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWQQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPMAKGLAP
GSQQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETLQRPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAILAMRDEQNSCITSPPKAA
CKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWRQRLRFEISVCDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSAHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTVANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L3LC14|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Turnix velox|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNSSSMELIPIEFILPTSNKHTKVPEIMLLE
IAANCTVEQMKAQVWMRAMETSQTTDFYHTFTPDHFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIHVVQKQQPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIRDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A091NCF3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acanthisitta chloris|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGAYIRKTLALDK
TEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A4D9E8S3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Platysternon megacephalum|TrEMBL
MELGNYEQPVVMREETKRRRRRMKPYSAASNLSSMELISIEFILPTSNKHTKVQETMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHKFTPDQFILQYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGKIYVVQKQKPTEAVQEFQTQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYSMHPWITSKPLPEYVFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PNMILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDDPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIVGIDIPVLPRNTELTVFVEANIQHGQQLLSQRRTISKPFTEEVLWNTWVEFDIKI
KDLPKGALLNLQIYCGKAQALSTKVSLQSHDSPNSDSKCKTQLLYYVNILLIDHRSLLRS
GEYVLHMWKISGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEAIVDTDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKREAWDHSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQIIKLLHKVTMDIKSVSAEKYDVTSQVITQLKQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQIHSNQRKKGMIEIVKDATTIAKIQQSTVGNTGAFKDEILNQWLKDRCVIEE
KFQAAVERFVYSCSGYCVATFVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGIN
KERVPFVLTPDFLFVMGTAGKKTSLHFSKFQDICVKAYLALRHHTNLLIILFSMMLMTGM
PQLTSKEDIEYIRDALTVGKNEEDAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVE
KHSA
>A0A669CT18|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MDRQQIQVSDEESQVPREESRRRRRKKAITSSCSNSMDQITVEFVLPTAARGGSGSDTLQ
LDVAGNWTVEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTCKPLPEHLLSKINNGHILVVIHIGTASQTIKVSID
DTPTLVLVSFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLK
NGEEIHLVLEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKQPQIPNSKGKQSFILRLLYYVNLLLIDHRSLLRQGEFILHM
WKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDWAVGG
EDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHECMRVPRAYPKLLG
SVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDD
DVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSKHYQQRYA
VLLEAYLRGCGENMLQDFRKQVTQALQKVTREIKTMSADKYDVTPQVVFQLRQKLENLQS
SGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADSTTLSKDPIGIIFKDGD
DLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIANIQQSVV
GSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITE
SGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKA
YLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICR
EKGWMVQINWFVHLVLGIKQGVEKRST
>A0A669ED06|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGHPAALRHVREREHQRHR
>A0A8C8FJL1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MEQQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKGVALWATLCCLPAPSLFCIGHILLVIHRNKAS
QTIKVSIDDTPVQALQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDF
HWVRQCLKNGEEIHLVLESAPNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVF
TISLWDCHRKFRFKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLW
NTWLEFNIRIRDLPKGARLSLQVSCGKAQTQISKGTSSGNHDCNKTKSRLLYYVNLLLVD
HRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYPVALP
KSREGKEAGGEGREAEGGERGQREMPNHLRKQFEAIVETDPLHPLSQEDKELLWHFREEC
MRHPRAYPKLLGSVRWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRS
MAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQ
VVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTT
LSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIV
KDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVL
GVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKS
SPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRTEE
EAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A7F8RWL5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptonychotes weddellii|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTMRVPTRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFRVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLNMWPSVPDEKGELLNPTGTVRSNPNTESAAALIICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALSDFVKVSSQKTTKPQTKELMHLCIR
QETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDTQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7F8QUZ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptonychotes weddellii|TrEMBL
MCFGFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECFKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
HPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVDCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQCLYSS
>A0A2Y9GKS1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neomonachus schauinslandi|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTVRVPTRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFRVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKQLQLREILERRGSGELYEHEKDLVWKMRHEVQERFPEALARLLLVTKWNK
HEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQ
VLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTH
HMKVLMKQGEALSKLKALSDFVKVSSQKTTKPQTKELMHLCIRQETYLEALSNLQSPLDP
STLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNGDDLRQDMLTLQMIQLM
DVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLN
WLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLG
NFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHL
FALMRAAGLPELSCSKDTQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHN
VSKDNRQ
>A0A8C9P169|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Spermophilus dauricus|TrEMBL
MELENYEQPVILREDNLRRRRRMKPRSVAASLSPMELIPIEFVLPTSQRDTKIPETALLH
VAGHGNVEQMKAQVWLRSMETSVAADFYHRLGPDHFILLYQKKGQWYEIYDKYQVVQTLD
CLRYWKMLNKSPGQIHVVQRHAPSEETLAFQQQLTALIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVASRDARLYAMHPWVTSKPLPEYLSKKITNNCIFIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDRPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIFCGKAPALSGKASAETPSSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLQDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLETLQNSNLP
KSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQA
AVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKERV
PFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLQRASKEDI
EYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A8C9QGF2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Spermophilus dauricus|TrEMBL
MPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPILKLVTRSCDPAEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRRKMRIFSEEKIQSLVGLSWINWLKQTYPPEHEPSTVE
NLENKLYGGKLIVAVHFENCQDVFSFQVSPEMNPIEINELAIQKRLTIHGKEDEASLYDY
VLQVSGRVEYVFGDHPLIQFQYIQNCVMNRTLPHFILVECSKIKKMYEQEMIAIEAAINR
NSSNLPLPLPPKKTRVISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHEISGKND
HIWNELLEFDINICDLPRMAQLCLAVYVGLDKVKTKKSTKTINPSKYQTIRKAGKVHYPV
AWVNTMVFDFNGQLRSGDIILHSWSLFPDELEEMLNPMGTVQTNPYTENATALHIKFPEN
KKQPYYYPPFDKIIEKAAEIASSDSANVAINIMDNHFLLTLDAKEWGRPLLYIYICIYIY
INMLHIYIYKISSGSSI
>A0A8C9PMI0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Spermophilus dauricus|TrEMBL
MPLGIDCPMEFWTEVEKNQSVVVDFLLPTGIYLSFPVSRNANLSTIKQMLWHEAQNEPLF
HMLRDPEAYVFTCVNQTAEQQELEDKQQRLCDVQPFLPMLRLVTRQGDRMEKLINSQISL
LIGKGLHEFDCLQDPEVNDFRTKMCQFSEEAAAHRQQLGWEAWLQYSFPLQLEPSTRSWG
DSNTSQISNPDLLVNVKFEGSRESFTIQVSTKDVPLALMACALQKKAKVYQHLTMEQPED
YVLQVNGRHEYLYGSYLLCQFKVRPSRSPLHSGIPPSSVSLWSLGQPFCIELIQGSKINA
DEQMKLVVQAGLFHGNEMLCKTMSSLEVSVCSEPMWKQHLEFDINICDLPRMARLCFALY
AVMEKAKKVYSRKKKSKKEDCPIARANLMLFDYKDQLKTGELCLYMWPSMRKETLEVLNP
MGTVHSNPNTESAVTLVIYLPEMAPHPVYYPALEKPMGEVLLACGRLSLEMLLNALHPAS
AGPGLGSSQQGHLLQILELGHHWEHGPTTKEEKLQLQGILEQRGSGELYEHEKDLVWKMR
HEVQEHFPEALAHLLLVTKWNKHEDVAQMLYLLCSWPELPVLNSLELLDFSFPNCHVGSF
AIRSLQKLTDDELLQCLLQLVQVLKYKSYLDCELTQFLLDRALANRKIGHFLFWHLRSEM
HVPSVALRFGLIMEAYFRGSTHHMKVLMKQVEALSKLKALSDFVKVSSQKTTKPQTKELM
HLYMRQDTYLEALSHLQSPLDPSTMLAEVCVERCTFMDSKMKPLWIMYSSEEAGSADSVG
IIFKNGDDLRQDMLTLQMIQLMDALWKQEGLDLRMTPYGCLPTGDCMGLIEVVQHSDTIA
NIQLNQSNLAAMAAFNKDALLNWLKSKNSGEALDRAIEEFTLSCARYCVATYVLGIGDRH
SDNIMIRENGQLFHIDFGHFLGNFKTKFGIKRERVPFILTHDFVHMIQQGKTSDNEKFER
FRGYCEQAYSILQCHGLLFLQLFALMQAAGLSELSSSKDIQYLKDTLALGKTEEEGLKHF
RVKFNEALRESWKTKVNWLAHNLTKDNRQ
>H9GIG2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anolis carolinensis|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCLPNGMIVTLECLREATLLSIKHDLFKEARKYPLFH
LLQEESSYIFVGVTQEAEREEFFDESRRLCDLRLFQPILKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDPEVQEFRRNILSVCREAVETRGSAGPQSQALYVYPPNVESSPELPKH
VYSKLDKGRIIVTIWVIVSPNNDKQKYTLKTPHDALPEQVIAEAIRKKTRSMHLSPEQLR
LCVQEYQGKYLLKVCGCDEYLLEKYPLSQYKYMRNCITIGRLPHLMLMSKESLYSQLPAN
VFVLPSYARRSATSAHVNGDVPSKSLWSINSLLRIKILCATYVNVNIRDIDKIYVRTGIF
HGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLPDLPRAARLCVSICSVKGRKGAKEEHCP
LAWGNVNLFDYKDTLVAGKMALNLWPVPHGLEDLLNPIGVGGSNPNKETPCLELEFTWFS
HTVKFADPTEIEEHANRAMSRELGLNYCMVGLSNRLARDSSLDESELEQLRNICNRDPLS
EITEQEKDFLWRHRHYCVNIPETLPKLLLSVKWNSRDEVAQMYCLVREWPLIKPELSMEL
LDCNFPDPVVREFALKCLVKGLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLTMKALTNQ
RIGHFYFWHLKSEMHSKPVSQRFGLMLEAFCRGCGMYLKHLNRQVEAMEKLINLTDILKQ
EKKDETQKMQMKFLVEQMRRPDYMEALQGFICPLNPVHQLGNLRLDECRIMSSAKRPLWL
NWENPDIMSELLFTNHEIIFKNGDDLRQDMLTLQIIRIMESMWQNQGLDLRMLPYGCLSI
GDCVGLIEVVKSSHTIMQIQCKGGLKGALQFNSNALHHWLKDKNKGEGYDAAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGVQECTKTKEFERFQEMCYKAYLTIRQHANLLINLFSMMLGSGMPELQSFDDVAY
LRKTLALDKSEQEALEYFTKQMNEAHHGGWTTKMDWIFHTIRHMPLSEASHD
>A0A7L2MJU7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhadina sibilatrix|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWRQAQQEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQRPEDYT
LQVNGKCEYLYGNYPLHQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKAA
CKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
WEVAVCSEPVWRQRLDFDISICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6Q2Z7F3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPAMTDLMDMWAAHSQVSGDNLVSVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQTY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALPDQEVKDFRSKMFRISEEKMQRVQLMNWSEWLQACFCPQLEPVVG
AAAGTDGVNDKQAETTSLKVCPSTTPSELMEQALRKWLTTHGPEEEGRQAQQYILRVSDK
LEFLCGDHPLIQSGRKYLRKCLNRATVTSRRLLSVLSAVSAFPFWLNRTLLVRVQVQVRA
GLFHGTELLCKPAVSSESSGRSEHVWNRMLEFDIQVSDLPRMARLCFAVYAIMDKVKKAR
TSLHYPIAWVNTMVFDYKGQLKTGDITLHSWSSFPDELEEMLNPIGTIQTNPYTENATAL
HIQFPDYIAHPIVFPPFDKVGASWQLLHSTLLPAILEIGSFSCPALPPGVDYPPLPPPSC
VQGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKH
EDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQV
LRYEPYYDCALTRFLLDRGQGNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYCRGSIPH
IEVLKKQVEALSKLKSVNELIKLGTIKNVRSKTKEAMLTKEAMMTCLRQSGYTETLSDLH
SPLNPSVLLSGINVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQI
LRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKD
ALLNWLKEKNSGDALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFG
HILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNL
FITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNW
MAHNVVKDNRS
>A0A2I3MD87|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Papio anubis|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGL
FHGTELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKST
KTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMG
TVQTNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPV
LKEILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQI
WPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALS
RFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALN
KLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCK
YMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRML
PYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRA
IEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVP
FILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTS
VKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7L3C3W3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pelecanoides urinatrix|TrEMBL
MELGDYEQPVIMREENKRRRRRMKPHCTSSNLSSMEVISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSHTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRVTSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3B3UAI3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia latipinna|TrEMBL
MDRQQIQVSDEEREVAREESRRRRRKKAITSASSTSMDQISVEFVLPTVARGGSSPDSLL
LEVAGNWTVEQVKAQVWMKAVSLNLCPDFYQRFCPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPTDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPNLYSMDPWVTRKPLPEHLLSKVNNGYILVVIHVSTSSQTIKVSID
DTPSQVLASFFAKTANKRVLLGIPEHLSDEDFVLRVCGREEYLYGEKALQSFNWIRQSLK
NGEEIHLVLETPPDPELDLVQREDWAQVDDCTGVAGTHEQLTIAEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPEFMVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKQPQTPNSKSSYHDNTSGSSTLEGKTKNRLLYYVNLLLIDHR
SLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPK
SREVGRDCGAGSEEGDGGERGQREMPNHLKKQFAAIVSTDPLHPLSPEDKELLWHFRHEC
MRDPRAYPKLLGSVRWGKQEDVLATHRLLDRSNAWDTSGLDVGLAMQLLDCHYSDAQVRS
MAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGENMLQDFRKQVEMTEALQKVTREMKAMSADKYDVTQQ
VVIQLRQKLETLQLSGLPESFRVPYDPGLRAGTLLIEQCKVMASKKKPLWLQFKRADPTT
LSKDPVGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIV
KDATTIATIQQSVVGSTGAFKDEILYQWLRDKCVSEEKFQQAVERFLYSCGGYCVATYVL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKS
SPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSED
EAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A7N4PVT5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sarcophilus harrisii|TrEMBL
MPPGVDCPMEFWSKEENQIVEVDFLLPTGVYLNFPVSRNANLSSIKEVLWHNAQSEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVARQGDRVKKLINSQISLL
IGKGLHEFDSLGDPEVNDFRTKMGQFCEEAAAHRQQLGWEAWMHYNFPLQLEPSARGLGA
GALRGPSRTLFVNVKFEGNEESFTFQVSPNDFPLALMACALKKRVTVFRQPALERPEDYT
LKVNGKYEYLYGSYPLYQFQYICRCLHNGQTPHLTMVHCSSILAMRDEQSNFPAQTPKLR
TKPPPIPMKKPSSVSLWALEQPFCIELIQGSKVNADERMKLVVLAGLFHGNEMLCKTVSS
SEVTVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWSSVPGTAALEPEGPVGLGGGCEWGEAQPLLLRPAEPHG
HRLQQLREILERKVAGELYEHEKDLVWKMRHEIQEQFPEALARLLLVTKWNKHEDVAQML
FLLSSWPELPVLSALELLDFSFPDRHVGSFAIQSLRKLTDDELFQYLLQLVQVLARVPPD
RVTVPAGRPHRKIGRSSLSSEMHVPSVALRFGLIMEAYCRGSNHHMKALMKQGEALNKMK
ALNDFVRVSSQRTTKPQTKELMHVCLRQEIYMEALSNLQSPLNPSTLLSEVCVEQCTFMD
SKRSRGSQAAGEAAGSCSPGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGC
LSMGDRTGLIEVVSHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALERAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILT
YDFVHVIQQGKTNNNEKFERFRSYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDI
QYLKDSLALGKTDEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7J8KEG6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rousettus aegyptiacus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRVPSRALLVNVKFEGSEESFTFQVSSKDVPLSLMACALRKKATVFRQSPVEQPEDYA
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIQLIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVNVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALIICLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRASGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELAKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPQTKELLHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSEGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A1U7QRI0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mesocricetus auratus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVDDFRTKMRQFCEEVAAHRQQLGWEDWLQYSFPLQLEPSARSWRA
GILRVANRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEDYA
LRVNGRHEYLYGNYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPAKKPSSVSLWSLEQPFCIELMEGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAP
HPVYFPALEKILELGRHGERGHITEEELQLREILERRGSGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDSYVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQ
ETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGRAGSVGIMFKNG
DDLRQDTLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGQLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A812CKN5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sepia pharaonis|TrEMBL
MFINMFSCKEKKDKGRNYCERKGWNKKKKIRKKFDYALAWGNLQMFDFNHRLLSDKGRIH
LWPMPQGMDDLLNPIGIPGSNPNQDCPCLDIEFDKFSHSVTFDMEKFDEYCRRNSQDGYT
QDSYVEHRPPDEKQMKQLEELVSRDPLSELSEQEKDFVWKLRNTCLVLPHSLPKLLNSVK
WNDRGDVAEIYRLLQKWPTLSPEDALELLDCSYMDTNIRNFAVDCLNKGLTNDKLSQYLL
QIVQALKYEPYLDNCLTRFLLKRALLNQRIGQFFFWHLRSEMHETSIRLRFGLILEAYCR
GCGAFLRNLLKQLEALDKLAKLSDKMKSDFMREEDQKRFLTEQLSQADYQEALQRFISPL
NNSHMLGDILVQHCYLKSSKKRPLWLVWQNPDPLAEYWLSYYKLIFKNGDDLRQDMLTLQ
VIRIMDSIWKNEGIDLRMIPYGCLSTGKEMGLIEVVPAAKTVMAIQHRGGKAASMQLDSS
QLHKWIRERNPKEQYDVAIDTFTKSCAGYCVATFVLGIGDRHSENIMLTEEGQVFHIDFG
HFLNHKKKKFGINRERVPFVLTEDFIKVIAKGADQPQKNKLFEEFQELCGTAYLALRKHA
KLFITLFTLMLSCSIPELQSLDDIGYLRKTLAVEKSEQEAATYFQEHSGWHHHLYAGHFC
LLNVSTKSCSLLIPSSLFFIHFFFSVLLSLSLSLFLPLFSLSLSLLSLSLLSLSSLSLSL
PLFSLSLSASLLSLSLCLSSLSLSLCLSSLSLSLSLFSLSLSLSLSLSPLSLSLSLSLSL
SLLSLLFFSLSLSFSLSLLSLSLSLSLSLSLCLSLSSLSLSLLSSLSLFLSSLSLFSLLS
LSL
>A0A3B4TX45|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola dumerili|TrEMBL
MPPGKYGMQEEWAKEGVREIMMDFLLPTGIFLKFPVSPNDTIKNIKKMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERQLLPWQQWMEYSFPCDLEPCCSPCGS
AKSKNTKKIFINVKFEACDESFMLQQDPQDHPGALMRSALKKKATVFRSLRQEPEDYTLQ
VNGSWEFIYGNHPLCQFKYIFSCLRNGQNPHLTMVHHSTVSKYQEDQGRMCSQVYKSRSL
SRPPPLPLKKLVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQRLEFDINVADLPRMSRL
CFALYAVIEKTKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKS
DLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPLDKVLLSATQRRMFFEDEKELLW
KLRTDVRDHYPESLSKLLLITKWNKREDVVQMVSLLKNWPDLPAIHALELLDYSFPDPTV
RSFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLR
SEIHVASVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDFVKSGSQRMTAEDLK
ICIKQDSYVEALSDLMSPLNPSIILSEICADKCRFMDSKMKPLWLMYKNHWTQGDMVGII
FKNGDDLRQDMLTLQMIQLMETLWKKEGLDLREKLDQAIEEFTLSCAGYCVATYVLGIGD
RHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKF
ERFREYCERAYKILCRNGMLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALK
NFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A8C3IDW9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysemys picta bellii|TrEMBL
MPPGIYCPVEFWSKEENQTIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVRDPEVNDFRAKMRQFCEEKAAKRQQLSWMAWMEYNFPLQLEPLAKGPRT
GPLRVPNKNIFVNVKFESGGESFTFQVSPKEFPVMLMSYAIKKQATVFRHQTVESPEDYT
LQVKGKCEYLYGNYPLYQFQYIRSCLHHGLMPHLTMVHCSSIIAMRDEQTNCTAHTPKMV
SKPPPLPKKKPTHESLWSLNQPFYIELVQGSKVNADERMKLVVQAGLYHGNEMLCKMVSS
AEVNVCSEPVWKQRLDFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQSNPNTESAAALVICFPSGIP
HPVYYPSFEQLLELGRNGDYTRATPEDPEEKQQLREILERRSHTELYEHEKDLVWKMRFE
IRDQYPEALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFTI
NSLKKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSNYHMKVLMKQGEALNKMKALNDFIKVSSQKATKPQAKEMMHV
CMKQETYLEALSNLQCPLNPTVILAEVCVDHCTFMDSKMKPLWIVFNNEEAGGRGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRD
YCEKAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3B4U624|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola dumerili|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TLPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRVTEEKMQRVQKMTFAEWLQACFSPQLEPA
AGTAITDGVNDRSPDLKVTIHFDQSQDSASLKVPSSCTPTELMELAVRKWLTTHGPEEEA
WRGQYVLRLSQCLEFLFGDHPLIQYKYIRTCIQAKESPHLTLVHTSTVKAMFDREMSTIG
AVVSRKSSNPPLPLPPKRRVPTQVQTCVWDVSCPFKIVLVNASKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESSGRSDHTWKESMLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDINLHCWSSFPDELEEMLNPIG
TIQTNPYTENATALYIHFPEYSSHAVIFPPFDKILEKAAEIARASDCAPMGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLSPRDALELLDFNYPDQYVREYAVRCLRDMSNEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAQGNRKIGHFLFWHLRSEIHMPAVSIQFALILEAYCRGSIPHIEVLKKQVEALS
KLKSVNELIKLGTTKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGI
NVERCRYMDSKMKPLWIVYNNKLMGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAS
LDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSG
DALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGYTEKFGRFVPPCPSVSFH
>A0A3B3E0H2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias melastigma|TrEMBL
MHPGIYGMLEEWEDGEQEINMDFLLPTGIFLKFPVSRNDTIKHIKEMVWRNARSEALFSG
LGDPDGYVFTCINQTAEREELEEEFRRIRDVKPFMCVLRLVAREGNRQEKLTNTQISLLI
GKGLHDFETQKNHEVNEFRTKMRAFCEEKALERQNLPWQRWLEYSFPCDLEPCRTPSGFG
SVKIKSSKIFINVKFEASDESFMLQQDCHDLPVALMKSALKKKATVFRSLRQEPEDYILQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPQLTMVHHSTVSRFQEEQSRMCNQMFKTRSL
SRPPPLPLKRLTNHLSCLYLITTRCLCALPLQLVVQAGLFHGSDLLCKVVTSLDVTVCSE
PMWDQKLEFDINVSDLPRMSRLCFALYAVIEKTKKPKSTKKKNKKADCPIAWVNTMVFDY
KDQLKTGEFLLSMWPSVPDDKSDLLNPMGTVEKNPNVESAAGLLIRFPNIRPHPLYYPSL
EKHLKLKEIMDNKHYTEFFEDEKDLLWKLRTEIREHYPESLSKLLLITKWNKREDVVQVV
SLLKKWPDLPAIHALELLDYSFPDPAVRAFTVRCLRKLSDDELLQYLIQLVQVLKYESYL
DCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIKILNKQ
NEALAKMRALSDFVKSGSQKMTVEDLKLCIRQETYLEALSDLLSPLNPSIILTDICADKC
RFMDSKMKPLWLMYKNPSSPGDMVGVIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRM
IPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPGDKLEQ
AIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERV
PFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYKILCRNGTLFVNLFAMMKAAGLPELT
SFKDIQYLKDSLALGKTEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A6I9XUR6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Thamnophis sirtalis|TrEMBL
MPPAMADILDIWAIDSHIAADSSITVDCLLPTGIYISLEVPRDATICHIKQLLWKQAHSY
PLFHLLLEIDSYMFSCVNQTAVREELEDETRRLCDIRPFLPVLQLITRSCDPGEKLDSKI
SVLIGKGLHEFDALQNPEIKEFRLKMRQISEEKMQSLMGLSTMNWLKHTYPPELQPAIQD
NFQDKLYGGNIVVAIHYENCQDVFSFQVSPNINPIKLNELAIRKWLTIHGKEDEEVDPCD
YVLQVNGRMEYVFGDHPLIQFQYIHCCVINRALPQLTLIECSTIKAMYEQEMIAIEAAVN
RKSNNLPLPLPPKKSRLTQSVWEIGHPFKILLVNGSKLNTEEIAKVHIRAGLFHGNELLC
KPIVSSEITGRNDHVWNEPLEFDINVCDLPRMARLCFVVYAVMDKMKNKKSAKALNPSKY
QTMRKAGKVHYPVAWVNTMVFDFKGQLKTGDLLLHSWSSFPDELEEMLNPMGTVQTNPYI
ENATTLQIRFQEYSKCPIYYPPFDKILEKAAEIARNSDCSGMPGRGGKKFYIELKEIMER
DPLSQLCENEMDLIWTLRFDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPR
EALELLDFNYPDQYVREYAVACLRQMSDEELAQYLLQLVQVLKYEAFLDCALSRFLLEKA
LANRRIGQMLFWHLRSEMHIPAVSLQFGVILEAYCRGSITHMKVLSKQVEALNKLKTLNS
IIKLNAMKQSKAKGKDTMHTCLKQNAYKEALSHLQSPLNPSVLLSELCIEKCKYMDSKMK
PLWIVYSNKAFGADMVGIIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLELRLLPYGCLAT
GDYSGLIEVVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNTGEDLDQAIEAFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQCCEEAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKNDDEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A4W5LTY9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDTQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLPEP
GGNKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKVTNVLFFPYLQQNTSSLWSIEEPFHIHLLQGYRVNADEG
MKLVVQAGLFHGSELLCKVVTSCEVNVCSEPLWDKKLVFDISVSDLPRMSRLCFALYAVI
EKAKKPRSTKKKNKKADCPLAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGT
VEKNPNVDSAAGLLIRFPNIRPHPLYYPHFDKVHLLLHTRFNKITILVPTGLQYVQSTPS
LLSLYCAAQHMKLKEIVDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKLLLITKWNKH
EDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQLVQV
LKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGNIYH
IKNLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLLSPLNPS
IMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIFKNGDDLRQDMLTLQMIQLMEI
LWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWL
KSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNF
KSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFA
MMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLA
KDSRL
>A0A4W5PM89|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MPPRPSSGELWGMHLMPPSIMVDCLLPNGMILTLECTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDAEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVSIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A4W5LTD1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGMVWRNASSEPLYGALSD
ADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFDTQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLPEPGGNK
TKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDYTLQV
NGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQVSKSRSLS
KPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVVTSCE
VNVCSEPLWDKKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPLAWVN
TMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHP
LYYPHFDKVHLLLHTRRHQHEMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRK
LRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHVSSVSL
RFGLILEAYCRGNIYHIKNLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQE
AYMEALSYLLSPLNPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIFKNGDD
LRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSN
SAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKE
TGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQA
YKILCRNGTLFVNLFAMMKAAGLPELTKWNENALKSLS
>A0A6J3QBN8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tursiops truncatus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFSVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPLKKPASVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKQLQLREILERRGSGELYEHEKDLVWKMRHEIQEHFPEALARLLLVTKWNK
HEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQ
VLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTH
HMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDP
STLLAEVCVEQCTFMDSKMKPLWVLYSNEEAGSDGTVGIIFKNGDDLRQDMLTLQMIQLM
DVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLN
WLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLG
NFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHL
FALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHN
VSKDNRQ
>A0A8C2X2D9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
AVTMPSGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNASSEA
LFGALGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRVEKLTNTQI
SLLIGKGLHEFEAQKNHEVNEFRTKMRMFCEEKAQERQMLPWQQWMKYSFPCDLEPCCSP
PEYGSVKSKNNKKIFINQDPQDLPVALMRSALKKKATVFRSLRQEPEDYTLQVNGRWDFI
YGKHPMCQFKFCHILFTLYPHKPSGPVAEKQSRKNNASTEISMMSKKLNSTIIRPKKIFL
HFCTQLLSFCRKALVVQAGLFHGSELLCKVVTTSEVTVCSEPLWDQKLEFDINVADLPRM
SRLCFALYAVLEKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPD
KSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPLDKVPIPKGGGKTLHFTLSNS
HTYMKLKEIMDNKNSTEFFEDEKELLWKLRTEVRDHFHESLSKLLLITKWNRHEDVVQLV
SLLKNWRDLPGIHALELLDYSFPDPAVRSFTIRCLRKLSDNELLQYLIQLVQVLKYESYL
DCDLTTFLLERALSNWRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIRLLTKQ
NEALGKMKALSDFVKSGSQKMTADDLKLCIRQESYLEALSDLLSPLNPSIILAEICADKC
RFMDSKMKPLWLMYNPGAQEDMVGIIFKKGDDLRQDMLTLQMIQLMENLWKKEGLDLRMI
PYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDPA
IEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVP
FILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNATLFVNLFAMMKAAGLPELTS
FKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>I3LYL9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ictidomys tridecemlineatus|TrEMBL
MELENYEQPVILREDNLRRRRRMKPRSVAASLSSMELIPIEFVLPTSQRDTKIPETALLH
VAGHGNVEQMKAQVWLRSMETSVAADFYHRLGPDHFILLYQKKGQWYEIYDKYQVVQTLD
CLRYWKMLNKSPGQIHVVQRHAPSEETLAFQQQLTALIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVASRDARLYAMHPWVTSKPLPEYLSKKITNNCIFIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDRPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIFCGKTPALSGKASAETPSSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLQDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLETLQNSNLP
KSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYS
CAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDF
LFVMGTSGKKTSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYI
RDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A060Y0S4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MEQQVSDEEEPQPVVLREEIRRRRRKMKAFTSTFSVAVDQIAVEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCVRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELSDRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVYTISLWDC
HWKFRVKILGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNAWLEFN
IRIRDLPKGARLSLQVSCGKAQTQISKGTSSYQDNGGSPGGGGSGSHDGSKTKNRLXXPF
QYYRLHSAPWDV
>A0A8C9VLR6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MPPAMTDILDIWAADSQLSNEDYVTVDFLLPTGIYIQMEVPREATIQHIKLLLWKQASTY
PLFAFLGEMESHMFECVNQSAVHEALEDETRRLCDVRPFLPVLKLVPRNCGRAERLNSKI
GTLIGKGLHELDALQDQEVKDFRVKMFRISEEKMQRVQMMTWMEWLQSCFSPQLENGVID
GLQEKLFDGALKVIMHFDQSQDTASLMVSPTITPRELTEQAVRKWITTHGPEEDESSCGE
FLLRVSNKLEFLYGEHPLIHYKYVRACVIGKDTPHLTLVHCGMVQAMFEKELSAIGAVVN
RKTSNPPLPLPPKRRGVSSLYTESSGRSEHVWNHTLDFDIAVCDLPRMARLCFAIYAVMD
KVKKQKSTKNAHINKYQTIRKAGKVHYPIAWVNTMVFDYRGHLKTGDNILHCWSSFPDEL
EEMLNPIGTVRTNPYTENATALHIYFPEYSSCPVVFPPFDKILEKAAEIARSSDCLPMVG
RGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDM
AQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVRCLKDMSDDELSQYLLQLVQVLRY
EPYYDCALTRFLLERAQTNRKIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEV
LKKQVEALSKLKAVNELIKLGTIKNARKTKEAMLTKEAMLTCLRQTGFTETLSDLHSPLN
PSVVLSGINVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLM
DLLWKEANLDLRIVPYGCLATGDRSGLIEVVSAAETIANIQLTSSNVAAAAAFNKDALLN
WLKEKNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILG
NFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGNFRQYCEDAYLILRRNGNLFITL
FALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHN
VAHNRS
>A0A8C2TMD2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coturnix japonica|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGAIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLSHTPVKNIFVNVNFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYTLQVNGKY
EYLYGNYPLYQFQVSLLSCFDKRVCPPCTHFSGRVVDGSADEMSSARQVTFLAMPNYGSL
WSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLD
FDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGE
CCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNAASHPVYYPSFDGGRNVPV
AGKEGDPSKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLTITKWNKHE
DVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQYLLQLVQVL
KYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHM
KVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQETYLEALSHLQSPLNPSI
ILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDVL
WKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALLNWLK
SKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFK
TKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYMILRRHGPLFLHLFAL
MKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSK
DNRQ
>A0A8C2TNL5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coturnix japonica|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGAIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLSHTPVKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQVSLLSCFDKRVCPPCTHFSGRVVDGSADEMSSYHQPPKDG
SEPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNAAS
HPVYYPSFEQLLELGRNGELPRSQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYP
QALAKLLTITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKL
TDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALR
FGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQET
YLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDL
RQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNM
AATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRET
GQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAY
MILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALR
ESWKTKVNWLAHNVSKDNRQ
>A0A087YMI3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia formosa|TrEMBL
MPPGKYGTQEEWEQDGDREIYMDFLLPTGIFLKFPVSRNDTIRNIKKMVWKNASREPLFF
GLGDPDLYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRSEKLTNAQISLL
IGKGLHEFEAQKNHEVDEFRTKMRTFCEEKSLERQNLPWQRWMEYSFPCELEPCSSPATG
GSSKSKHGKKLFVNIKFESSDESFMLQQDSQDLPVALMKSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGQHPLCQFKYIFFCMRNGQNPQLTMVHHSTISKYQEDQGRVCSQMYKTR
SLSRPPPLPLKKQNTSSLWSINEPFYIHLVHGSKVNADEGMKLVVQAGLFHGSELLCKMM
TSSEVTVCSEPLWDQRLEFDINVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGDFLLSMWPSVPDDKSDLLNPMGTVQKNPNVDSAAGLLIRFPNI
RPHPLYYPPLEKTIDPEMNGNTDFPSKDEYLKLKEIMDNKNYTEFFEDEKELLWKLRIEV
RDYFPECLSKLLLITKWNKREDVVQMVSLLKSWPELPAIQALELLDYSFPDPAVRYFTIR
CLKKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLKSEIHVA
SVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDIVKTGSQKMTVDDLKLCIRQE
SYLEALSDLLSPLNPSVILFEICADKCRFMDSKMKPLWLMYKNPLEQADMVGIIFKNGDD
LRQDMLTLQMIRLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEIVKSSDTIANIQRNNSN
SAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEKA
YKILCRNGTLFVNLFAMMKAAGLPELSSSKDIQYLKDSLALGKSEDEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A8B9QYC1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPYCTSSNLSSMELIAIEFILPTSNKHTKIPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYQAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGGLSTKTNLQSHDSPNSDSKCKTQLLYYVNLLLIDHRFLLRSGEYVLHMWKIPDK
LTSATNPDKENSMAISIVLDKYCHPIALPKHRITSDSQGDRTRAEMPNQLRKQLEEIIAT
DPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQEIVAKTYQLLAKKEAWDQST
LDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFL
LKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLHDFMKQVQVIEL
LHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSSKLPESFRVPYDPGLRAGALVIEKC
KVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWEAESLD
LCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEILNQWLKERCVIEEKF
QAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKE
RVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQ
LTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKH
SA
>A0A835NJC8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lamprotornis superbus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRSKMCQFCEDKAAKRQQLGWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIRKQATVFRHETLQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAILAMRDEQNNCITSPPKAA
CKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWRQRLEFDISVSDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQHYIEEELSQIPCWICATAVNPGTLHNVALKVMVK
AESSQSISFSLPVSWSLMVLWCAARIRNTPRMIMNTRKLTHTTITTVAVLGTTATQNTTL
DHDIALHRGNGDTGLFIETPERQKQVCSQGRSMDSRLQPHCTGMLQPSTRTHLTVLEIFS
LRMPGVGNCLEF
>A0A6P3RWL7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pteropus vampyrus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQFEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLSLMACALRKKATVFRQSLVEQPEDYA
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHCSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIQLIQGSKVNADERMKVVQAGLFHGNETLCKTVSSS
EVNVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWA
NLTLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAPH
PVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRASGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELAKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPQTKELLHLCMRQ
ETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSEGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A6P6D3G5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pteropus vampyrus|TrEMBL
MELENDEQLVVLREDNCRRRRRMKPRGSAASLSSMELVPIEFVLPTRQRTSKTPEIVLLH
VAGHGNVEQMKAQVWLRALETSVVADFYHRLGPDNFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHSPSEETLAFQRQLTALMGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEKDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPAQDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNSDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCGKAPVLSGKAPAETPSSESKGKSQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPNPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGE
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQRVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVVEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKSSLHFQKFQDICAKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEDDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A3Q1J906|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPAMTDLLDMWAAHSPLAGQTPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
NFPLFPALGEMESHMFECVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRISEEQMQRVQMMTWKEWLQACFSPQLEPA
AGTAITDGVNDRPADLKVTIHFDQSQDSASLKVPATCTPLEVIELSMRKWLTTHGPEEEE
WRGQYVLRVSHCLEFLCEEISLFQYKYIRTCMQAKEPPHLTLVHTSSIKQMYDKEISTIS
AVVSRKSSNPPLPLPPKRRTCVWDVPSPFKIVLVNASKVNAEETAKVNVRAGLFHGAELL
CKPAVSSESSGRSDHTWKENTLEFDIFVNDLPRMTRLCIAIYAVMDKVKKQKSTRNAHIN
KYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATALHIHFPEYSSHPIVFPPFDKILEKAAEIARSSDCTNMGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLCP
RDALELLDFNYPDQYVREYAVGCLQNLVSCCLLSPLTSDEELLQYLLQLVQVLRYEPYYD
CALTHFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRCNIPHIEVLKKQV
EALSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLQSPLNPNVL
LSGINVDKCRYMDSKMKPLWIVYNNKLLAGDNLGIIFKNGDDLRQDMLTLQILKLMDLLW
KEANLDLRIVPYACLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKE
RNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKS
KFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALM
LTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKD
NRS
>A0A8C3PKW2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calidris pygmaea|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVKDFRAKMRRLSEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRPTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTTVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A672MJR9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQS
GKSHSGKKILVNVKFEGSEETFVLQQDPQDLPMFLKRNALRKKSNVFRPAKQEKPEDYTL
QVNGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKFQEEQGGLSNQVSRTRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKRLTTGLHFQSYTGSIRSVL
WVYWKSLLLWLEYLDCPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVE
KNPNIDSTAGLLIRFPNIRPHPLYYPPIEKLNELGMNGEKVVATKEEHLKLREIVDNKNY
TEFFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVGLLRKWQDLPAIHAL
ELLDYSFPDPHVRSFTIRCLGNLRNDELFQYLLQLVQVLKYESYLDCDLTCFLLERALSN
KKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSIFLIKSLMKQNEALNKMKALNDFVK
SGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLW
LMYKDKYDHVGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGL
IEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCV
ATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQE
GRTNNSEKFERFREYCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLAL
GKSEEEALKNFKVKFNEALRESWKTKVNWMMHSFAKDNR
>A0A672QW20|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPAKTDQLDLWAESGLNGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLGTGSLE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHSPEEDIGTRSDY
VLRVSGRFEFLFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKTMFEKEISTIGSVLAR
KTSNPPLPLPPKKRPPTQLHTCVWKVHSLFRINLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKPAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSP
RDALELLDFNYPDQYVREFAVICLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLER
AQSSRKIGHFLFWYLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVS
ELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLQSPLNPNILLAGVHVERCKYMDS
KMKPLWIVYNNKLLGGDTVSIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGC
LATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
HDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDI
QYLKVKTCPVQHENENCNFVH
>A0A851YNY0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Halcyon senegalensis|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVLNSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMARGIGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQPFYVELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPLWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGELPRAMPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRAEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDLVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDLLEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C9UBN9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Serinus canaria|TrEMBL
MKQYEGKDHSTQFSRAFILISSGMELGDHDQPVVMRDENKRRRRRMKPHCTSSSFSSMEL
ISIEFILPTSNKHTKAPEIMLLEIAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFV
LQYQKKGQWYEIYDKHQVLQTLDCILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDL
IGYDVTDVSNVHDDELEFTRRRLVTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITN
NNIFIIIHRGTTSQKIKVSIDDTPDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRICGR
DEYITGDTPIKDFHWIRQCLKNGEEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHE
QLTIDGKDHERVFTISLWDCNRKFRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQILSQR
RTSSKPFTEEVLWNMWLEFDIKIKDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDA
KCKTQLLYYVNLLLIDHRFLLRSGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSM
AISIVLDKYCHPIALPKHRISSDPQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKEL
LWHFRYESIKHPKAYPKLLSSVKWGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCN
FSDENVRAMAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHF
LFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSA
EKYDVTSQVIAQLRQKLEKLQGSKLPESFRVPYDPGLRAGTLVIEKCKVMASKKKPLWLE
FKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGN
KIGMIEIVKDATTIAKIQQSTVGNTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAG
YCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYV
MGTSGKKTSLHFHKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDA
LTVGKSEEDAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L3QPT0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cettia cetti|TrEMBL
QVLWKHAQHEPLFHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREG
DRAKKVINSQISLLIGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYN
FPLQLEPMAKGLGTGSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQAT
VFRHETVQKPEDYTLQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMR
DEQSNCITSPPKATSKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAG
LFHGHEMLCKTVSSWEVAVCSEPVWRQRLDFDISICDLPRMARLCLALYAVIEKAKKARS
TKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTE
SAAALVICFPSVAAHPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTEL
YEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELL
DFSFPDRYVGSFAINSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKI
GHFLFWHLRSEMHVPAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSS
QKATKPQTKEMMHMCMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVF
NNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGL
IEVVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCV
ATYVLGIGDRHSDNIMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQ
GKTNNNEKFERFRGYCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLAL
GKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7N8Y3F4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPAMTDLLDIWAAHSPLAGQAPAHITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINEQEVKDFRSKMFRFSEERMQRVQMMTCTEWLQSCFSPQLEPA
GYTLMIDLNRSLFSFLVPQDSISLKVPSSSTTMELIELAVRKWLTTHGPEEETRRGQYVL
RVSHCLEFLCGDHPLTHYKYIRICMQAKESPHLTLVHISTIKGMFDKEISTIRAVVTRKS
CNLPLPLPPKRRVPTTCVWDVSSPFKIVLVNCSKVNAEETAKVQVRAGLFHGTELLCKPA
VSSESSGRSEHTWKESTLEFEISVSDLPRMTRLCFAIYAVMDKVKKQKSTKNKQACHYPI
AWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATALHILFPEY
SSHPIVFPPFDKGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPK
LLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVCCLRDMSDEEL
LQYLLQLVQVLRYEPYYDCALTHFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALIL
EAYCRCNIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQS
GYSETLSDLHSPLNPNVMLSDINVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDD
LRQDMLTLQILRLMDLLWKEASLDLRIVPYGCLATGDRAGLIEVVSSAETIANIQLTSSN
VAAAAAFNKDALLNWLKERNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRS
TGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEA
YLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSDEEALKQFRQKFDEAL
RESWTTKVNWMAHNVAKDNRS
>B7ZM44|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSAQTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEELQLREILERRGSGELYEHEKDLVWKLRHEVQEH
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMRQ
EAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>M4A2Z1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xiphophorus maculatus|TrEMBL
MDRQQIQVSDEEREVAREDSRRRRRKKAITSASSASMDQISVEFVLPTAARGGSSPDSLL
LEVAGNWTVEQVKAQVWMKAVSLNLCPDFYQRFCPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIRYWRALKRDVGRIQLAPRPQPTDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDANLYSMDPWVTRKPLPEHLLSKVNNGYILVVIHVSTSSQTIKVSID
DTPSQVLASFFAKTANKRVLLGIPEHLSDEDFVLRVCGREEYLYGEKALQSFNWIRQSLK
NGEEIHLVLETPPDPELDLVQREDWAQVDDCTGVAGTHEQLTIAEKDHERVFTISMWDCN
RKFRVKVLGIDIPTLPKVPELTVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKQPQTPNSKSSYHDNTAGSSTLEGKTKNRLLYYVNLLLIDHR
SLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPK
SREVGRDCGAGGEEGDGGERGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRHEC
MRDPRAYPKLLGSVKWGKQEDVLATHCLLDRSNAWDTSGLDVGLAMQLLDCHYSDAQVRS
MAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGENMLQDFRKQVEMTEALQKVTREMKAMSADKYDVTQQ
VVIQLRQKLETLQLSGLPESFRVPYDPGLRAGTLLIEQCKVMASKKKPLWLQFKRADPTT
LSKDPVGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIV
KDATTIATIQQSVVGSTGAFKDEILYQWLRDKCVSEEKFQQAVERFLYSCGGYCVATYVL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKS
SPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSED
EAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A2K5ZK31|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mandrillus leucophaeus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGYWVIYKGKNDEELSQYLLQLVQVLKYEPFLDCALS
RFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALN
KLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCK
YMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRML
PYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRA
IEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVP
FILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTS
VKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A2K5YVM5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mandrillus leucophaeus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A6P8PAM0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCIPNGMIVTLECLREATLLGIKHNLFKEARKYPLFH
LLQDESSYIFVGVTQEAEREEFYDETRRLCDLRLFQPILKVIEPVGNREEKILNREIGFA
IGMPICEFEMVKDPEVQEFRRNILSVCKEALDLREASGPHSQALYVYPPNVESTPELPKH
IYNKLDKGLIIVTIWVIVFPNNDKQKYTLKIPHDCLPEQVIADAIRKKTRSMHLSPEQLK
LCVQEYQGKYILKVCGCDEYLLEKYPFSQYKYIRNCITIGRLPHLMLMSKESLYGQLPAN
IFIMPSYARRSVTSCYMNGDVPTKSLWSINSLLRIRILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYLTDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINLFDYKDTLVAGKMALNLWPVPHGLEDLLNPIGVGGSNPNKETPCLELEFSWYT
HAVKFPDTPQIEEHANWSMSRELGLNYCLVGLSNRLARDSSLIENEMEQLRNICNRDPLS
EITEQEKDFLWRHRHYCINIPETLPKLLLSVKWNSRDEVTQMYCLLREWPLIKPELSLEL
LDCNFPDPMVREFALKCLVKGLTDDKLSQYLIQLVQVLKYEQYLDNILARFLIKKALTNQ
RIGHFFFWHLKSEMHSKTVSQRFGLMLEAFCRGCGMYLKHLNRQVEAMEKLINLTDILKQ
EKKDETQKMQMKFLMEQMRRPAYMEALQGFICPLNPVHQLGNLRLEECRIMSSAKRPLWL
NWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIRIMENMWQNQGLDLRMLPYGCLSI
GDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWLKDKNKGEGYDAAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGIQECTKTKEFERFQEMCYKAYLVIRQQANLFINLFSMMLGSGMPELQSFDDIAY
LRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPLSEAGHD
>A0A8D0M712|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLKLQIYCGKAPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPSQWAKDQIEVCRDKGQVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A093TM07|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phalacrocorax carbo|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADASISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLNHTYPPEQEPV
IPESFQDKLYGGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHIWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSIQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAATAAFNKDALLNWLKECNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8B7R3N4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hipposideros armiger|TrEMBL
MPPGVDCPMEFWTKEENQSVLVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLTNSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSTSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQHLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVGRAGW
EAGARPRPVLQPRGHLAWGQPWEVRAASSLKPPLGSHKVSKAMVPNCPVPPPREALDRAI
EEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPF
ILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCS
KDIQYLKVKARAGPHQ
>A0A341BU57|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neophocaena asiaeorientalis asiaeorientalis|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
AKPPPIPLKKPASVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEELQLREILERRGSGELYEHEKDLVWKMRHEIQEH
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMQLCLRQ
ETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A4Z2GK15|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Liparis tanakae|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHQ
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDSVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKVSVVWAIYLLKNIMISNYIKRHVKYFVQV
VNVYFFV
>A0A8B9XKT6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus grunniens|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTK
PQTKELMHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEA
GSDGTVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVV
LHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYV
LGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTN
NSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTE
EEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L1TBU2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aramus guarauna|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKTQGLSTKTNLQSHESPNSDSKYKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8B9XPY3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus grunniens|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKFVRLWGGE
>A0A3M0JN38|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hirundo rustica rustica|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHVRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLRQMRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQ
VEALNKMKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELH
VEKCRYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGL
DLRILPYGCLATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGE
DLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIK
RERVPFILTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A091UZ70|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nipponia nippon|TrEMBL
MELGDYQQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A091UTX3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nipponia nippon|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKSGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYIVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A5A9PIG3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Triplophysa tibetana|TrEMBL
MGGRWGRPIRRQVLVMEQAGEDEPPVVRKEEKRRRRKMKAFSSSSAVPTDQVAVEFVLPT
INKNSKSPDTVQLDVTGNWTVDQVKAQLWQKALTTKICPEFYQKYSPDQCILLYQKKGSW
YEIYDMQQVFQTLDCIRYWKALRKEVGKIYMVIKPQSTEDSLQYQRFLNHLIGYDVTDDT
NVHDDELEFTRRKLLTTRKIELSDRDARLYLMDPWITSKPLPEYLLSKVSNNHILMVIHK
GTTSQTIKVSIDDTPYQVLQSFFIKIANKRALIGIAEDSSESDFVLKVCGREEYLYGNYA
IKDFIWIRQCLKSGEEIHLVLEDPPNPEQDVVQKEEWSQVDDCTGVAGTHEQLTVTEKDH
EKVFTISLWDCNRKLRVKIIGIDIPVLPRTSELIVFVEASIFHGQQLLAQERTTSRPFTE
EVLWNTWLEFNIKIKDLPKEARLSLEVSCGKAQSQTSKESDCKSKSRLLSYVNLLLVDHR
SLLRQGEFILHMWKMPEKNEDTVNADKLTSATNPDKHNSMAVVILLDRYCHPVVLPKRKD
FQNTSEMEGGRGQRDMPNHLRKQFDQIIATDPLHPLSAEDMELLWHFRQECLRDPKAYPK
FFSSVKWGKQEAVSIIHRLLEQSTVWDRSVLDVGLALQLLDCNFSDENVRTIAVRKLETL
GNDDVLRYLLQLVQAVKFEPYHDSALARLLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQ
RYAVILEAYLRGCGEVMLQDFRKQVEITEALQKVTREIRQITAEKYDVSAQVVLQLRQKL
EALQVSGLPESFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADATTLSSDTIGII
FKDGDDLRQDMLILQILLIMESIWELESLDLWLLPYGCISTGNKIGMIEIVKDATTIANI
QQSTVGNTGAFKDEILSQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDN
IMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYLMGTAGKKSSPNFLKFQN
VCLKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGCTEEEAKQHFLDQ
IEICRDKGWTVQFNWFLHLVLGIKQGVEKRSA
>A0A8C5YV47|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Marmota marmota marmota|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTI
MQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRH
NSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREF
ERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALE
YFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>W5NFS7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lepisosteus oculatus|TrEMBL
VMEQREDVELPVVFRDESTRRRRKMKAFTSNSLVTMDQITIEFVLPTSNKFNKTPEVILV
DVAGNCTVEQVKTQVWMKAVAANLCPEFYQKYSPDQCILRYQKKGHWYEIYDKHQVFQTL
DCIRYWKALKKDQGRIHLASRPQPTDKSQQYQRYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRMIELAERDPKLYSMDPWITSKPLPEYLLNKISNNHILVVIHRHTSSQTIKVSIDD
KPLQILQSFFTKIAKKRSLLGIPEEVSEQDFVLRVCGREEYIFGNHAIKDFHWVRQCLKN
AEEIHLVLESAPNPDQDVVHKEDWSLVDDCTGVAGSHEQLTIVEKDHEKVFTISMWDCNR
NFRVKVVGIDIPTLPRNSELIVFVEASIFHGQQLLAQDRTSSKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVFCGKAQTQTGKAGFQESVNYDSKCKNRLLYYVNLLLIDHRSLLRQG
EYILHMWKVPEKSEDHSSINADKLTSATNPDKDNSMAIVILLDKYCYPIALPKGQDSVET
EGERGRREMPNHLRKQFEEIVVTDPLHPLSPEDKELLWHFKQECMRFPRAYPKFLSSVKW
GKQEAVLATHQLLEKHDTWDRSPLDVGLAMQMLDCNFSDANVRTMAVRKLETLGDDDVLR
YLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILE
AYLRGCGEAMLQDFRKQVEITEALQKVTREIKTMSADKYDVSVQVVFQLRQKLENLQSSG
LPGSFRVPYDPGLRAGALVVEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDL
RQDMLILQILLIMESIWETESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGN
TGAFKDEILNQWLRERCLNEDKFQLAVERFVYSCAGYCVATYVLGIGDRHNDNIMITESG
NLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTFGKKTSPHFQKFQDVCVKAYL
ALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKTEEEAQKHFLDQIEICRDK
GWTVQFNWFLHLVLGIKQGVEKRSA
>A0A8C4NTX4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MPPAMTDLLDIWAAHSPLAGHALDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLISKGLHELDGINDQEVKDFRSKMFRMSEERMQKVQMMTCMEWLEACFSPQLEPA
PGTAITDGLNDRPADLKVTIHFDQSQDSASLKVASSSTPIDLMELALRKWLTTHGPEEEA
WRGQYVLRVSHCLEFLCGDHPLIQYKYIRTCMQAKESPHLTLVHTSAIKAMFDKEISAIG
AVVGRKSSNPPLPLPPKRRAPTQVQTCVWGVSSPFKIVLVNGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESSGRSDHTWKDSTLEFDISVSDLPRMTRLCFAIYAVMDKVKKQKST
KNAHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHPIIFPPFDKILEKAAEIARANDCAPMSRGGKKFHIE
LKEIMERDALSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSNEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAQRNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALS
KLKSVNELIKLGTIKNARKAKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGIN
VEKCRYMDSKMKPLWIVYNNKLMGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNTGD
ALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKVSHINAHTHTHTHTHFHSASRQHLHPNTGHLFSWCICACLHLRPLWQ
LSRCVGEETESKAIDRNKQDVKLNL
>A0A667WPA0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MGHAFPSRFSFKFIKLIKEISLNTKIGKCVLSLTVYVSLYFDTEMLLMVWRNAATEPLFS
ALGDSDAYVFTCINQTAEREELEDESRRISDVLPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHDFEAQKNHEVNEFRSKMRSFCEEKALERQLLPWHQWIEYSFPCELEPCSSLPES
GNTKSKNTKKIFVNIKFEASDVSFSLMKNALKKKATVFRLVRQEPEDYTLQVNGRWDFIY
GKHPLCQFKVSPPLTTNCLNIAFFRHYFLSKCCSTNTSSLWSINEPFYIHLVQGSRVNAD
EGMKVGAGLFHGSELLCKVVTSSEVAVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVI
EKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPGALNDLLNPMGT
VEKNPNVDSAAGLLIRFPNIRPHPLYYPPHDKIGDMEKNGDMSVATKEELKEIMDNKNYT
EFFEDEKELLWKLRAEVRDRYPESLSKLLLITKWNKREDVAQMLSLLRNWPDLPALHALE
LLDYSFPDPTVRAFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNK
RIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGNIYHIKVLSKQVNALGKMRALSDFVKT
GSQKMTAEDLKLCIRQESYLEALSDLLSPLNPSIILSEICADKCRFMDSKMKPLWLMYKN
QWVQGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKTGLIE
VVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEDKIDQAIEEFTLSCAGYCVAT
YVLGIGDRHNDNIMIRETGQLFHIDFGHILGNFKRKLGINRERVPFILTYDFVHVIQQGR
TNNSEKFERFRECCERAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGK
SEEEALKNFKVKFTEALRESWKTKVNWMMHSLAKDNRP
>A0A674AEQ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MEQQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKGAALWATLCSNFHYLFPEDVCEGDYILRVCGR
EEYIYGNHPVRDFHWVRQCLKNGEEIHLVLESAPNPGQDLVQKEDWAQVDDCTGVAGTHE
QLTIDEKDHERVFTISLWDCHRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQE
RTSSKAFTEEVLWNTWLEFNIRIRDLPKGARLSLQVSCGKAQTQISKGTSSYQDNGGSPV
GGGSSSHDGNKTKSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTS
ATNPDKASSMAVAILLDKYCYPVALPKSREGKEAGGEGREAEGGERGQREMPNHLRKQFE
SIVETDPLHPLSQEDKELLWHFREECMRHPRAYPKLLGSVRWGRQEAVLATHRLLERSSV
WDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSA
LARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQV
EMTEALQKVTREIKAMSAEKYDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGAL
VVKQCKVMASKKRPLWLQFKRADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWE
EESLDLSLLPYGCISTGNKIGMIEIVRDATTIANIQQSVVGSTGAFKDEILNQWLRDKCV
SEEKFQQAVERFVFSCGGYCVATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFL
GISKERVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLM
TGMPQLTSKEDIEYIREALTVGRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQ
GGDKRSA
>A0A674BZP2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
ICLFLCQQSCLFILFDVYVLNKDTVGSLLQRFCFPLSGFIYRPLQTFLSLSDADAYVFTC
INSTAEREELEDETRRLCDVRPFMSVLRLVAREGDRVEKLTNTQISLLIGKGLHEFDSQK
NHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEPGGIKTKGTKKIF
VNVKFEASDVSQEPQDLPMILMRSALKKKATVFRSVRQEKPEDYTLQVNGRWEFIYGKYP
LCQFKYIFSCLRGGQTPHLTMVHHSTIVKYQEEQGCLGSQVSKSRSLSKPPPLPVKKVRG
QPLGTTLVVQAGLFHGSELLCKVVTSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFAL
YAVIEKAKKPRSTKKKNKKADCPLAWVNTMVFDYKDQLKTGEFLLSTWPSVPGDLLNPMG
TVEKNPNVDSAAGLLIRFPNIRPHPLYYPHFDKVHLILKKWREGYSHQGGGKGLSILKEI
VDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKLLLITKWNKHEDVAQMVAFLQKWPDL
PALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLL
ERALSNKRIGHFLFWHLKSEMHVSSVSLRFGLILEAYCRGNIYHIKSLWKQNEALNKMKA
LNDFVKSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLLSPLNPSIKLSEICADRCKFMDS
KMKPLWLMYKNKWVQGDAVGIIFKNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGC
LSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEF
TLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILT
YDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDI
QYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDSRL
>A0A674BYE3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPGEYGMLGEWKKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRPFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPMILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKVTNVLFISYYQQNTSSLWSIEEPFHIHLLQGYRVNADEG
MKLVVQAGLFHGSELLCKVVTSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVI
EKAKKPRSTKKKNKKADCPLAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGT
VEKNPNVDSAAGLLIRFPNIRPHPLYYPHFDKVIATKVEVRDSLLFYVHSTPSLLSLYCA
AQHMKLKEIVDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKLLLITKWNKHEDVAQMV
AFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQLVQVLKYESYL
DCDLATFLLERALSNKRIGHFLFWHLKSEMHVSSVSLRFGLILEAYCRGNIYHIKSLWKQ
NEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLLSPLNPSIKLSEIC
ADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIFKNGDDLRQDMLTLQMIQLMEILWKKEGL
DLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPED
KLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNFKSKFGIN
RERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFAMMKAAGL
PELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDSRL
>A0A7L2HNV2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sagittarius serpentarius|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPSKNIFVNVRFQSGGESFTFQISPKEFPVTLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAL
HPVYYPSFEQLLELGRNGEQPRAAPEDPEERLQLKEILERRSYTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8B9D797|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anser cygnoid|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPYCTSSNLSSMELIAIEFILPTSNKHTKIPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHDSPSSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A663LQT7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Athene cunicularia|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEIILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDSPPDLNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIESLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
NLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGSSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C9BSH6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phocoena sinus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
AKPPPIPLKKPASVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMQLCLR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A852IFX8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tricholaema leucomelas|TrEMBL
MPPGIYCPMEFWSKGENQSIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWRQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAP
HPVYYPSFEQLLELGRNGEQLRATAEDPEEKQQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGQVASLFHSVLLDALEQAIEEFTLSCAGYCVATY
VLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKT
NNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKT
DEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q1FZN1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acanthochromis polyacanthus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESCPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAMYCLLKEWPLMEPE
SALELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKK
ALTNQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLT
DTLKQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAK
RPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPY
GCLSIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDL
FTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVL
TQDFLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSF
DDIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A3B4FHW2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pundamilia nyererei|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKSIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRAFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKTKNSKKIFINVKFEASDESFMLQQDPHDLPLVLMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNSQNPHLTMVHYSTVTKCQEEQGRMCNQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPCVPDEKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKYFKLKEFMDNKNYTEFFEDEKELLWKLRTEVRDHYPESLSKLLLITKWNK
REDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLRKLSDDELLHYLIQLVQ
VLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASVGLRFGLILEAYCRGNIH
HIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESYLEALSDLLSPLNPSIIL
SEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWK
KEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGN
FKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLF
AMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEALRESWKTKVNWMMHSL
AKDNRP
>A0A8C5J3F9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Junco hyemalis|TrEMBL
MPPGIYCPTEFWSKGENQSIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPNKNIFVNIRFQSGGESFMFQISPWEFPITLMSYAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPYYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQVGHGDTCRNSLTMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKL
TDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPAVSLR
FGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCMKQET
YREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKNGDDL
RQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNM
VATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRET
GQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCERAY
MILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKVRGRAHTRGEN
>A0A3B3XL77|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia mexicana|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMSKESLYSQLPME
NFTMPSYARRISTATPYMNGETATKCLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYVTEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMSMIEDHANWNISRELGFNYSHPGLSNRLARDKPLTESDNEQLRQVCNRDPL
SEITEQEKDFLWSHRHYCINIPDILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHALHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A811ZE96|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nyctereutes procyonoides|TrEMBL
MEPQGREPPVVLREDHRRRRRRMKARGPAAGLPSMELIPIEFVLPTSQRSSKAPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYQRLGPDHFVLLYQKKGQWYEIYDRYQVVQTLD
CLRYWQLLHRSPGQIHVVQRRAPSAATRAFQRQLTALIGYDVTDLSNVHDNELEFTRRRL
LTPRVLEVAGRDPELYAMHPWVTSKPLPDYLRKRIPNNCVFIVIHRGTTSQTVKVSADDT
PGAILRGFFAKMAKKKALMGIPEGQSERDFVLRVCGRDEYLVGDTPLQNFQWVRQCLKNG
EEIHLVLDAPPDPALDEVRKEEWPLVDDCTGATGYHEQLTIHGKDHESVFTVSLWDCDRR
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFSIKI
KDLPRGALLNLQVYCSKAPTLSAKASADAPGSASEARGKAQLLYYVNLLLIDHRFLLRRG
EYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDP
EGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKW
GQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLH
YLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLE
AYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLN
LPESFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDL
RQDMLILQILRIMESIWETESLDLYLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGN
TGAFKDEVLNHWLKEKCAIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETG
NLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYL
ALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDK
GWTVQFNWFLHLVLGIKQGEKHSA
>A0A3Q2DWA3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinodon variegatus|TrEMBL
MPLAMPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLW
KQAQNFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAE
RLLDSKIGVLIGKGLHELENINDQEVKDFRSKMFRLSEEKMQRVQMMTCTEWLQACFSPQ
LEPAPLTTITDGLNDRPADLKVIIHFDQSQDSTSLKVSLSSCTPSELMEMAVKKWLITHA
PEEEAWRGQYVLRVSHCLEFLCGDHPLIQYKYIRTCLQAKETPHLTLVHSSTIKAMFDKE
MSAIGAVVSRKSSNPPLPLPPKRRNPTTCVWDVSSPFRIVLVKGSKVNAEESAKVQVRAG
LFHGTELLCKPAVSSESSGRSEHTWKDNALEFEISISDLPRMTRLCFAIYGVMDKVKKQK
STKNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNP
IGTIQTNPYTENATALHIHFPEYSPHPVVFPAFDKILEKAAQIARASDCISIGRGGKKFH
IELKEIMERDPLSQLCENEKDLIWTLRHDCYENFPQSLPKLLLSVKWSKHEDMAQLQALL
QIWPRLSPRDALELLDFNYPDQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYYDCA
LTHFLLDRAQSNRKIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEA
LSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSEALSDLNSPLDPSVLLS
DINVEKCRYMDSKMKPLWIVYNNKLLNGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKE
ASLDLSPQYSNGLPWLKSTQLSLTVPPAFHQLFHIDFGHILGNFKSKFGIKRERVPFILT
HDFIHVIQQGKTGNTEKFGSFRQYCEDAYLVLRKNGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A3Q2DZZ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinodon variegatus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLVTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGSHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKVFLCCDHGVRGWPFLLKYSKGPIILLQPH
TSNVACFWSRTSFGGMPLHRRSRISRDTQLFPAKAQGGYYWRTRKNLSGWSRLSSKTTVA
PLQDITVTEMDLELLDIEEEQVLLMEFEHCPLAWGNINLFDYTHTLVAGKMALNLWPVPH
GLEDLLNPIGVTGSNPNKETPCLELEFDHFSCPVKFPNMSQIEEHANWNISTELGFNYSH
NGSSNRFARDNPLTESDNEQLRQVCNRDPLSEITEQEKDFLWRHRHHCINIPDILPKILL
AVKWNSRDEVAQMYCLLKDWPAIRPEQAMELLDCNFPDPMIREFAVKCLEKYLTDDKLSQ
YLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLES
YCRACGVYLKHLSRQVEAMEKLINLTDLLKQEKKDEAQKVQMKFLVEQMKRPDYMDALQS
FTSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWENPDMMSELLFQNNEIIFKNGDDLRQD
MLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGAL
QFNSHALHQWLKDKNKGEMYDQAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLF
HIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLA
IRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQEALDYFMKQMNDAHHGG
WTTKMDWIFHTIRQHAMN
>Q8CFF1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|TrEMBL
MPPAMADNLDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRRKMRKFSEAKIQSLVGLSWIDWLKHTYPPEHEPSVLE
NLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEDEASPCDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINR
NSSNLPLPLPPKKTRVISHIWDNNNPFQITLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKKKK
>A0A3B4Y8E4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola lalandi dorsalis|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGRL
IVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLRLCVQEYQGQY
ILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPASGFVTPSYSRR
TPQPSPCPGGGDGCPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRTGIYHGGEPLC
DNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEEHCPLAWGNVN
LFDYKDILVSGKVALGLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFSWFNQTVVFPD
EQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDAEQLRSLCSKDPLYELSEQEKD
FLWRHRHYSVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESALELLDCNFPDP
MVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFFW
HLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQK
TQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIM
SELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIE
VVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTRSCAGYCVATF
ILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQ
ESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALG
ETDTGVGGGVWWWWWTLCLSVSLSVSLCLHVSIYLSVSLCLCVSLCLHVFVYLSVSLSVS
LCLTCLSLREEPAGGVGVFHQTDERCSSWRLEHQDGLDLPHHQTHAKRALIYTHLYITHI
YI
>A0A7R8H1H9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lepeophtheirus salmonis|TrEMBL
MAPSSGELWGVNLMPHQVMVDCLMPNGVIVPLRCFRDSPLDVIKGDLWREAHNYPLFHLL
LDAHSYIFVSITQDGEKEEFFDESRRLCDLRLFQAILKLVEPQGNKEEKILNSEIGIALG
IPLHEFDEMKDPEVMEFRRELFEVTSRAVSQRNEKGKESQAFLCIPSGN
>A0A665UKU0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
YEIFKQDHRIMMNNYDDEPKFQREEIRRRRRKKAITSSSGTSMDQITVEFILPTVARGGN
SPDSLQLEVAGNWTVEQVKAQLWLKAVTSNLCPDFYQRFSPDHCILLYQKKGNLYEIYDK
HQVFQTLDCIRYWRALKKDVGRIQLVPRPQPSDESLHYQRYLNYLIGYDVTDVSNVHDDE
LEFTRRKLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVSNGHILVVIHIATASQT
IKVSIDDTPVLASFFTKTANKRVLLGIPENMCETDYVLRVCGREEYLYGDKPLQNFNWIR
QCLKNGEEIHLVLETPPDPNQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTVSM
WDCNRKFRVKVLGIDIPSLPKVPEFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNSWL
EFNIKIKDLPKGARLNLQVVCGKQPQTPNSKVNSFQDNAGGGKTKSRLLYYVNLLLIDHR
SLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPK
SRDVSRDVPAGAEEAEGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRQEC
MRDPRAYPKLLSSVRWGKQEDVLTTHHLLERSSAWDSSGLDVGLAMQMLDCHYSDAQVRS
MAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGEAMLQDYKKQVEMTEALQKVTREMKTMSADKYDVTAQ
VVFQLRQKLETLQLSGLPESFRVPYDPGLRAGGLMIEQCKVMASKKKPLWLQFKRADPTT
LSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIV
KDATTIANIQQSVVGSTGAFKDEILYQWLRDKCISEDKFQQAVERFLFSCGGYCVATYVL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKS
SPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRVED
EAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A093IBU8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fulmarus glacialis|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
VPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHIRAGLFHGTE
LLCKTIVSSEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKSMNT
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A452IE15|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gopherus agassizii|TrEMBL
MELGNYEQPVVMREEAKRRRRRMKPHSPASNLSSVELISIEFILPTSNKQVQETMLLEIA
GNCTVEQMKAQIWMRAIEMSQTTDFYHKFPPDQFILQYQKKGQWYEIYDKHQVIQTLDCI
LYWKVLEKKVGKISVIQKQKPAQAVQEFQTQLNDLIGYDVTDVSNVHDDELEFTRRRLVT
PRMIEVACRDPKLYSMHPWITSKPLPEYVLKKITNNNIFIIIHRGTTSQKIKVSIDDTPD
MILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNGEE
IHLVLDDPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRKFR
VKIVGIDIPVLPRNTELTVFVEANIQHGQQLLSQRRTISKPFTEEVLWNTWVEFDIKIKD
LPKGALLNLQIYCGKAQALSTKVNLQSHDSPNSDSKCKTQLLYYVNILLIDHRSLLRSGE
YVLHMWKISGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSDPQ
GDRTRAEMPNQLRKQLEAIIDTDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWG
QQEIVAKTYQLLAKREAWDHSSLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVLHY
LLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEA
YLRGCGKAMLHDFMKQVQIIKLLHKVTMDIKSVSAEKYDVTSQGSWEMLLGVGKITGGLT
FSFHVVTKFLLYLGGSCA
>A0A452IDU6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gopherus agassizii|TrEMBL
MELGNYEQPVVMREEAKRRRRRMKPHSPASNLSSVELISIEFILPTSNKQVQETMLLEIA
GNCTVEQMKAQIWMRAIEMSQTTDFYHKFPPDQFILQYQKKGQWYEIYDKHQVIQTLDCI
LYWKVLEKKVGKISVIQKQKPAQAVQEFQTQLNDLIGYDVTDVSNVHDDELEFTRRRLVT
PRMIEVACRDPKLYSMHPWITSKPLPEYVLKKITNNNIFIIIHRGTTSQKIKVSIDDTPD
MILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNGEE
IHLVLDDPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRKFR
VKIVGIDIPVLPRNTELTVFVEANIQHGQQLLSQRRTISKPFTEEVLWNTWVEFDIKIKD
LPKGALLNLQIYCGKAQALSTKVNLQSHDSPNSDSKCKTQLLYYVNILLIDHRSLLRSGE
YVLHMWKISGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSDPQ
GDRTRAEMPNQLRKQLEAIIDTDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWG
QQEIVAKTYQLLAKREAWDHSSLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVLHY
LLQLVQAVKFEPYHDSALARFLLKRGLRVSTSKLNNIKVTGIVKIDCFSGENHVY
>A0A452QLP1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus americanus|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRHSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLLDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIQI
KDLPRGALLNLQIYCSKAPAPTGKGSADTPGSEGKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLEAY
LRGCGTAMLHDFSQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A674GGV7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MPPAVTDSLDIWAVDSQIAADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQETVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSIKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYSRWQES
>A0A8C5CDC0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMLLTLECLREATLITIKHELFREARKYPLHH
LLQEQTSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILSVCKDSVELRDVSGPHSRALYVYPPSVESGQELPKH
IHSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMRLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYSQLPAD
AFVMPSYSRRISTATAYMNGELAAKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLGWGNINLFDYTHTLVANKMALNLWPVPRGMEDLLNPIGVTGSNPNKETPCLELEFDHF
SCLVKYPEMSSVEEHANWSVSREMGFSYNLSGQSSRMARDIALTEGDVEQLRQLSHRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIQPEHTME
LLDCNYPDPMVRCFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLIHLTDLLK
QEKKDETQKVQMRFLVDQMKRPDYMDALQSFTSPLNPAHQLGNIRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNRGETYDLAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKTEQVPKDRLSLSLSLSLSLSLSLSLSLSLSLSLSLSLSLSLSLSLSLSLS
LSLSLSLSLSLSLPPSLPPSLSLSLSLSLSLSLSLSPSLPPSLPPSLPPSLPPSLPPSLP
PSLSLSLSLSLSDIPWFPVCASGGVGLLHEADERRASRGLDHQDGLDLPHHQTARAQLGG
ASTRLHLTPPGITGLNLDWDHWSNPGLGSLV
>A0A8C2DI80|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGLCHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVA
QSGKSRSVKKILVNVKFEGSEVSEFMLIYHSFMLSGNSFLWYNAIKKSTVFRAAKQEKPE
DYTLQVNGRWEFIYGEYPLCQFKVSLKVTTSSRLHSYSTTLSDSRTHKIFKMLNHFFFSQ
QQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSNEVSVCSEP
VWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKD
QLKTGEFSLSTWPSVPDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKVRGK
KSNVLIVDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVGLL
RKWPELPAIHALELLDYSFPDPHVRSFTIRCLRNLSYVISNLMRFFFLFLNSDDELFQYL
LQLVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYC
RGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVV
SPLNPSIVLCELCTDKCKFMDSKMKPLWLMYKNKYDHVGIIFKNGDDLRQDMLTLQMIQL
MDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALL
NWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFL
GNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVN
LFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMH
TFAKDNR
>A0A7K9Z073|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Odontophorus gujanensis|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMTKGLGA
GLLHTPIKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINSIANPPKMA
VKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRTAPEDPEEKLQLKEILERRNHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLTITKWNKHEDVAQIISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHV
CMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCEKAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A669R1T0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phasianus colchicus|TrEMBL
FCFMSRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQ
YEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLIN
SQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPM
AKGLGTGLLHTPTKNIFVNVNFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYTL
QVNGKYEYLYGNYPLYQFQVSLLSCFDKRKSPNYGSLWSLEQSFYIELVQGSKVNADERM
KLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIE
KAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTV
QCNPNTESAAALLICFPNVASHPVYYPSFEQVGNTDSLASKLQLKEILERRSHTELYEHE
KDLVWKMRHDIRDQYPQALAKLLTITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSF
PDRYVGSFAINSLKKLTSFLCVDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRK
IGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLS
SPKATKPQAKEMMHVCMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIV
FNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTG
LIEVVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYC
VATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQ
QGKTNNSEKFERFRGYCEKAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLA
LGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C1J8P2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVAQS
GKSLLIFPSCAETFVLQQDPQDLPMLLKRNALRKKSTVFRAAKQEKPEDYTLQVNGRWEF
IYGEYPLCQFKVSLKVTTSSRLHSYSTTLSDSRTHVFLNLILLFSYFFFCIYILFYCNVK
FLVVQAGLFHGSELLCKVVISNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIE
KTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPDLLNPMGTVEKNPN
IDSTAGLLIRFPNIRPHPLYYPPIEKVRYYKRRGKKSNVLIVDNKNYTEFFEDEKELLWK
LREEVRQRYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHVR
SFTIRCLRNLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRS
EMHVPSVSLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTE
DMKVCIKQDTYMEALSDVVSPLNPSIVLCELCTDKCKFMDSKMKPLWLMYKNKYDHVGII
FKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANI
QRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFR
ECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKV
KFNEALRESWKTKVNWMMHTFAKDNR
>A0A8C1FY59|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVI
SNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKVNFVVLLNVSHETERDCGHKNYTEFFEDEKELLWKLREEVRQRYPESLPK
LLLITKWNKHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLSDDEL
FQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSLRFGLIL
EAYCRGSIFHIKSLIKGTALCCLKKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEAL
SDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQDMLTLQ
MIQLMDYTLLSNAALRMPVNWNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDEFTLS
CAGYCVATYVLGIGDRHSDNIMISETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDF
VHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYL
KDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A669PNX5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phasianus colchicus|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHTY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
NFQDKLYSGNLVVAIHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEIDPAD
YVLQVSGRLEYVFGDHPLIQFQYIHNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEVAIN
RKSSNLPLPLPPKKTRATTSVWDICSPFKIILLKGNKLNTEENAKVHVRAGIFHGTELLC
KTIVSTEISGRSDHAWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKSMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGEFVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCKYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C2DK18|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGLCHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVA
QSGKSRSVKKILVNVKFEGSEVSEFMLIYHSFMLSGNSFLWYNAIKKSTVFRAAKQEKPE
DYTLQVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQMS
RTRAPSKPPPLPLKRVRMHFYTGTRSVINRGTTSLQSLSFSQLVVQAGLFHGSELLCKVV
TSNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRDCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLY
YPPIEKVHFCVIAFCCFQLNELGMNGEKVHMKLREIVDNKNYTEFFEDEKELLWKLREEV
RQRYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHVRSFTIR
CLRNLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRSEMHVP
SVSLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVC
IKQDTYMEALSDVVSPLNPSIVLCELCTDKCKFMDSKMKPLWLMYKNKYDHVGIIFKNGD
DLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNS
NSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIR
ETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQ
AYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEA
LRESWKTKVNWMMHTFAKDNR
>A0A8C2B1E2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
IILRNFRICLVRREENKRRRRKMKAFTSTSAVSTDHIAVEFVLPTTNKNSKYPDTLHLDV
TGNWTVEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTLDC
IRYWKALRKEVGKIHLVIRQQPNEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRKLL
TPRKIELADRDPKLYSMDPWITPKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDDTP
VQVLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAISDFHWIRQCLKNGE
EIHLVLEHPPDPELDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRKF
RVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIKIK
DLPKGARLSLQVSCGKAQTQTSKENECKNKTRLLYYVNLLMVDHRSLLRQGEFILHMWKM
PEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERGQR
EMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEAVA
ITHCLLERSTVWDRSSHDVGLALQLLDCHFSDENVRTLAVRKLETLEDDDVLRYLLQLVQ
AVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCG
EAMLQDLRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDSFKV
PYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSRDTIGIIFKDGDDLRQDMLIL
QILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDE
ILSQWLSEKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDF
GHILGNYKSFMGISKERVPFVLTPDFLYVMCTTGKKSSPYFLQFQNVCLKAYLALRHHTN
LLIILFSMMLMTGMPQLSSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQFN
WFLHLVLGIKQGVEKRSA
>A0A1A8RQ58|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius rachovii|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLDCLRETPLISIKQQLFVEARKFPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDSEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIVSPTNSKQKYTLKVSHDSLPEQLIAESIRKKTRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIVVGRLPHLMLVSKDSLYSQLPAS
GYITPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYINVNIRDIDKIYVRT
GIYHGGEPMCDNVNTQRVPCSHPRWNEWLTYDLYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYSYCHGLSSRLACDSTVSASDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCINIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMESESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKVQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLR
>A0A670J904|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podarcis muralis|TrEMBL
MPPGIACPVEFWSKEANQSIQVDFLLPTGIYLTLSISCNASLNTIKQMVWHHAQFEPLFH
MLSGPESYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDALSDPEVNDFRTKMHQFCEERVTRRQQLSWKAWMEYSFPVQLEPSSSSLGR
KSPLQVPNKNIFVNVKFESGGESFTFQISPKEFPVTLMSYAVKKQATIFRHQRMNSPEEY
ALQVNGKCEYLYGNYPLYQFQVCAPLPNSISLWSLEQPYYIDLVQGSKVNADERMKLVVQ
AGLYHGHEMLCKMVSSSEVNVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKA
RSTKKKSKKADCPIAWVNIMLFDYQDQLKTGECCLPMWSSFPDEKGELLNPTGTVRTNPN
TESAAALVIRFPGILLYPVYYPSFEQVRRWWFAPLSLASLVCFLGQWKKVSHLHSVLRGK
QQLKEILERRSHTELYEHEKDLVWKMRHQVRDQYPGALAKLLVVTKWNKHEDVAQMIHLL
QSWPELPVLNALELLDFNFPDRYVGSFTVNSLKKLTDAELFQYLLQLVQVLKYESYLDCK
LTTFLLDRALSNRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKSLMRQSEA
LNKMKALNGIVKLSALKNPKPQTKEFMHTCLRQETYLEALSNLQSPLNPSVILAKVSVEL
CTFMDSKMKPLWIVFNNEEIGGTSNVGIIFKNGDDLRQDMLTLQMIQLMDILWKKEGLDL
RMTPYGCLSTGDKTGLIEVVMDSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDAL
DRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRE
RVPFILTYDFVHVIQQGKTSNSEKFERFREYCERAYMILRCHGLLFLHLFALMKAAGLPE
LSCSKDIQYLKDSLALGKTDEEARKHFQLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6G1R7P0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hypotaenidia okinawae|TrEMBL
GIYLNLSVSCNASLGTIKQVVWKHAQYEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRR
LCDIQPFLPVLRLVAREGDRVKKVINSQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCE
ERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGTGPLHTPTKNIFVNVKFQSGGESFTFQIS
PEEFPITLMSYAIKKQATVFRHETVEKPEDYTLQVNGKCEYLYGNYPLYQFQYIRSCLHR
GRTPHLTMVHSSAIIAMRDEQTNCIASPPKMAAKPPPLPKKKPNYGSLWSLEQSFYIELV
QGSKVNADE
>A0A7J8AA08|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pipistrellus kuhlii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWGINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLEMEFDWF
SSSVVKFPDMTVIEEHANWSVSREAGFSYSHAGMSNRLARDNELRENDKEQLRAICTRDP
LSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAM
ELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDIL
KQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A212CR17|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cervus elaphus hippelaphus|TrEMBL
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGAQLGPGGPPSAGPAPVPAPSPTPPLILALTWLPHLSGLHEFDSLQDPEVNDFRGKM
RQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGPGTLRVPNRALLVNVKFEGSEESF
TFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYTLQVNGKHEYLYGSYPLCQFQYIC
SCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRTKPPPIPMKKPSSVSLWSLEQPF
YIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSVCSEPVWKQRLEFDINVCD
LPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWP
SVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAPHPVYYPSLDKMLYLLCSWPELPV
LSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDR
ALANRRIGHFLFWHLRSEMHVPSVSLRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALN
DVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWVMYSNEEAGSDGAVGIIFKNGDGEQAGPREDPGGQGFHTPCHAALGGEGDPAGGGG
LLEDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQL
NKSNMAATAAFNKDALLNWLKSKNPG
>A0A668UEI3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
GQRGMKCTTRGWQAGESYSDCLTQKQCCEVMSHIYSSFLKMLSALFYETCVNQAAVHEEL
EDETRRLCDVRPFLPVLKLVTRNCGRAERLLDSKIGVLIGKGLHELDALNDQEVKDFRSK
MFRISEERMQQIQMMTFSEWVQACYSPQLEPAAVTAITAGVNDAPVDLKVIIHFDQSQDS
ASLKVSLSCTPNELMEQALRKWLTTHGSEDAVWRGQYILRVSQCLEFLGGDHPLIQYKYI
RSCLQAKETPHLTLVHTSAVKTMFDKEISAIGAVVSRKSSNPPLPLPPKRRAPTTCVWDV
PKPFRIVLVKGSKVNAEETAKVQVRAGLFHGTELLCKPAVSNESSGRSEHTWKDNTLEFE
ISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNPHINKYQTIPWVNTMVFDYKGQLKTGDII
LHCWSSFPDELEEMLNPIGTIQTNPYTENATALHIHFPEYSSHPIVFPPFDKGRGVKKFY
MELKEIMERDPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALL
QIWPKLSPRDALELLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYDCA
LTHFLLERAQRNRQIGHFLFWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQVEA
LSKLKSVNELIKLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLS
DINVEKCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKE
ANLDLRIVPYGCLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERN
SGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKF
GIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLT
AGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNR
S
>A0A2K5IJ17|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Colobus angolensis palliatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVCTLVCLFRSPVYIQIMDGPWNQLCSVRHIMLEECRIMSSAKRPLWLNWEN
PDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCV
GLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYC
VATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVIS
KGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKT
LALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A668UJ14|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRSKMFRISEERMQQIQMMTFSEWVQACYSPQLEPA
AVTAITAGVNDAPFPFLQDSASLKVSLSCTPNELMEQALRKWLTTHGSEDAVWRGQYILR
VSQCLEFLGGDHPLIQYKYIRSCLQAKETPHLTLVHTSAVKTMFDKEISAIGAVVSRKSS
NPPLPLPPKRRTCVWDVPKPFRIVLVKGSKVNAEETAKVQVRAGLFHGTELLCKPAVSNE
SSGRSEHTWKDNTLEFEISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNPHINKYQTIRKA
GKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATAL
HIHFPEYSSHPIVFPPFDKVTQHSIHSSDCYMVGRGVKKFYMELKEIMERDPVSQLCENE
KDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNY
PDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQRNRQIGHFL
FWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQVEALSKLKSVNELIKLGTIKNT
RSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDINVEKCRYMDSKMKPLWI
VYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRT
GLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFTLSCAGY
CVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVI
QQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSL
ALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8D0CNI1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MPPGKYGMQEEGDQEIMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNARSEALFSALGD
PDAYVFTCINQTAEREELEEESRRISDVRPFMGVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFEAQKNHEVNEFRAKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPECGSVK
SKNTKKIFINVKFEACDESFMLQQDPQDFPVALMKSALKKKATVFRSVRQEPEDYTLQVN
GRWEFIYGNHPMCQFKVSDRSRLKPQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQA
GLFHGSELLCKVVTTSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPR
GTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNV
DSAAGLLIRFPNIRPHPLYYPPLDKVRILKSDMEKNGDAAIVTKEERMKLKEIMDNKNHT
EFFEDEKDLLWKLRTEVRDHYHESLSKLLLITKWNRREDAVQMMSLLRTWRDLPAIHALE
LLDYSFPDPVVRSFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNW
RIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDFVKS
GSQKMTADDLKLCIRQESYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPIWLMYNP
CTQEDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEV
VKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDRAIEEFTLSCAGYCVATY
VLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRT
NNSEKFERFREYCERAYKILCRNGMLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKS
EEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A8D0ABI9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MDGQQIPVSDQEPKALREDTRRRRRKKAIMSSSCTSMDQISVEFVLPTAARGGNNPDTLL
LEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLAPRPQPSDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIQLADRDAKLYSMDPWVTRKPLPEHLLSKISNGHILVVIHIGTASQTIKVSID
NTPAQVTNVLQLESKLLGVCQHREEYLYGDKPLQDFNWIRQCLKNGEEIHLVLEAPPDTD
LDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVLGIDIPSLP
KIPEFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLEFNIKIKDLPKGARLNLQVN
ISFRCTRLCIHLFLFRLSGKIKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEESS
SSINADKLTSATNPDKASAMAVAILLDKYCYPVVLPKSRDVGRDAATGCEEAEGGERGQR
EMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRWGKQEDVL
ATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQ
AVKFEPYHDSALVRFLLKTALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCG
EDMLQDFRKQVEMTEALQKVTREVKAMSADKCDITAQVVFQLRQKLETLQSSGLPESFRV
PYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQDMLIL
QILLIMESIWETESLDLCLLPYGCISTGNKIGMIETVKDATTIANIQQSVVGSTGAFKDE
ILCQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDF
GHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTN
LLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQIN
WFVHLVLGIKQGVEKRST
>A0A7L4HIF3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scopus umbretta|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNSSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDYSELDFVLRICGRDEYITGETPIKDFHWIRECLKNG
EEIHLVLDNPPDPNEDEVRKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNTWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQV
>H3AT86|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Latimeria chalumnae|TrEMBL
MEIPETNSQMKLPALQCRNSNQCNDFLGDLSPKVILSFICVLPTKKPNDGVNEVVTVEIS
AHSTVRNLRLLIWMQARDISCQKEFYKIVDPAHCKLLYQKEKNWYEIYDDYQTLDSIRYW
RYMGMEKGQIYVHSKLKETKEQEDFQKRLTYLIGYDIGIMSFHGIDELSFARRKLASPRQ
TEIKQRDPWLYAMEPWITSVPFPENIKAWIGEELVVVIYYMGESNKMKVNINHTPSAIAE
CCVQRLIDKDIPVGKKEQDLVLKVCGREEYLTGDRPLVNFLWIRHCLKSKQEVHLSLIPV
PSFEDDDVTTEDWPLVDEFTGLTGTHENLQLGNQESDEITMISLWDCARKFRMKIIGIDI
PNLPTKAPQQVYIEASILHGRNILSSVISKIMPFTEEVIWNSWLEFNTLVKNLPKGSKLH
LSVNGIDNEYGPLKESKSSCQGFKDSDALKNKSKLLYFVNILLIDHRSLLQQGEHVLHMW
PYQMQEAGLFTNEAERLSSKTNPEIETSMAISIIFDSYCFPLALPYSKTSKSSSFSRPST
YQHQSKSKSMEESMLPNPVTVSGKESLRRFSEESARYGTSLPRFLSTINWGDMEAVQDLH
WLLQHWDPHNLDIVIALELLSINFADEKIRKMSVDRLEELQNDELMRYLLQLVQALKFEP
YHDSALARFLIRRALRSKRIGHFFFWYLRSEITGSPYFCDHFAVILEAYLMGCGKSMLEG
FSTQVQLVECLHQVVTDIKKIIPEESNLPASAAAQLQERLKMADLPQDFLVPFDPRIKAG
TILLNNCKIMASKKKPLWLEFTCSETEAINTPPVGIIFKHGDDLRQDMLIIQTLVVMDSI
WQENSLDLNLIPYGCISTGYRIGMIEIVRDAKTIATVQRSKGGTLGAFKNDALYDWLKSK
CKIEEMHYQALERFVTSCAGYCVATYVLGIGDRHNDNIMITEYGNLFHIDFGHILGNTKR
FLGMNRERVPFVLTPDFLFVMGRVNRKSSLYFQRFKDICIQAYQALRCHSNLLITLFSLM
MLTRIPELSCTRDIEYLKEALALGRDDQSAKDHFLNQISICENLDWTVQTNWWIHMVMGM
K
>A0A3P8NL22|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astatotilapia calliptera|TrEMBL
MDRQQIQVSDEECQVPREESRRRRRKKAITSSCSTSMDQISVEFVLPTAARGGSGPDTLQ
LDVAGNWTVEQVKAQVWMKAVTSNLCPEFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTRKPLPEHLLSKINNGHILVVIHIGTASQTIKVSID
DTPTLVLASFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLK
NGEEIHLVLEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNI
KIKDLPKGACLNLQVICGKQPQIPNSKGSSYQESTAGSSCLDGKTKSRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLP
KSRDVGRDWAVGGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHE
CMRDPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVR
SMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSKHYQQRYAVLLEAYLRGCGENMLQDFRKQVDMTEALQKVTREIKTMSADKYDVTP
QVVFQLRQKLENLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADST
TLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKK
SSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSE
DEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A6P7JDG3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Parambassis ranga|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRISEERMQRLQMLNCSEWLQACFSPQLEPA
AGTAITDGANDRPADLKVIIHFDQSQDSASLRVPSSFTPTDLMELAVRKWLTTHGPEEEV
WRGQYVLRVSHCLEFLCGDHPLTEYKYIRTCLQAKETPHLTLVHTSTVKAMFDRELCTIG
AVVSRKSSNPPLPLPPKRRVPTQVQTYVWDMSSPFKIALVKASKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESSGRSDHMWKDNTLEFEIAVCDLPRMTRLCFAIYAVMDKVKKQKST
KNAHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATELHIHFSEYSSHAVIFPPFDKILEKAAEIAKANDSLPGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRHDCHENFPQSLPKLLLSVKWSKHEDMAQLQALLQVW
PTLSPRDALELLDFNYPDQYVREYAVRCLRDMSDEELLQYLLQLVQVLRYEPYYDCALTH
FLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNAKKNKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGINV
ERCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDHLWKEANLD
LRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDA
LDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSNGQLFHIDFGHILGNFKSKFGIKR
ERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEDAYLVLRKNGNLFITLFALMLTAGLP
ELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>B0EMK9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Entamoeba dispar (strain ATCC PRA-260 / SAW760)|TrEMBL
MKLLQLILCFMLIAQIFAEDVENTVSIEGEEFELEDDNKYEREKAQISEKMRSSIEKKIA
RKIALREVAKKRQFDRKTSKIHRKLKKINTQIEGLQKRLHIYSKTRKSLKIKRTKLTSQK
KAAILKIKELRTSMQTKITKMEMKAMKKGKKINLTKKRALQLIQKNQARKIVREFTIKEN
RIKRQLKQLESKKSIMRRKIVHLQGVAKYLRAKLANVLKQKQEYAKKIQNKRIQLVKKAM
KYAKVFAMLNQVEKHIKHVEERLSVLVDERKRGKLSSRREYLMKKQKMIKKRIEVLKRRK
AERKARKLEINKMKQQMKEYNKKYHAEKKLKKAALRSAKRQVSYLKRQYKKAERAYNGAR
SLVKREKKAIALKGARLAFFQAKSAVYNLKKDIRDMKNISIQKVHAILRGLLKLKIIDAN
MRITEHKLSIKEYEVYKKKVVSRIQQLKKYGRRLDLCPANQRLLRKRLSINYRRLKHIAR
KISHSMKAIRIHQLRIGMMHKKLRMIAIKEYKHMKAMVRSLKASVKELKSTIRVAKFKKA
CAGVITRKRMNYIIKNAKNEIQSLKVEINDFRMKIKLVDEAIAEEKRQRLMVTKIDYHRA
KAALHEAKHGIRVISRKIQKNKELATSSTEPWKRRQYLSRNGKLTMKLVKLESMRKKLAQ
KVDMLKVKYNKLYQAEISEFLAYKTKWEVRKSKVIGELNRLAKQDSKITKKLRKGICELK
KCRILFSRKYNYLQAHKLQIVLYKINKKLEKIHSEYVRRSEARSFRIIKKRFNKQKKAYI
KNEHLLKHVRHQLTRLEKKIAVAEQRLPFLADNEKVIARGVVAALEKIKRNVQKKIKVLE
NQKTIIMKKYLALNKEYLIQLKKRMESDKKRKGELIAKRPETLRAALYELIPHKQQRAER
KLNRLDKELESLEKRSLEDAHRMKEAIRTRKFLQEAVKPKVVCTGGIINCRYCHSLGRIL
KVSLRNREEDRIILERLHHRCNKELPENQARCIDVAMRLTEVAVKVFDPVKFRVASACKK
IGVCGI
>A0A3B4BNP1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pygocentrus nattereri|TrEMBL
MPPAMTDQLDVWSDPGLDGDDQVTVDFLLPTGIYIQMDVPRESTIQQIKQMLWKQAQAYP
LFSLLGEIDSHIFECVNQAAVHEELEDESRRLCDVRPFLPVLKLITRNCGRAERLLDSKI
GVLIGKGLHELDALQDQEVKDFRIKMQRISEEKMQRVQTMSWGEWLHSCFPPQIEAGPFE
DDRNEGDIKITMHYNQSQDTASLKVSLSCTVAELMEQALRKWLTTHSSEENKGYLGDYVL
RISGKLDFLFGEHTLIHYKYIRSCLLAQEIPHFTMVHCSDVMAMFEHEISTIGAVLTRKS
SNPPLPLPPKRRGLSMHTCVWEVHSLFKIILVKGIKVNADETAKVQVRAGLFHGTELLCK
PAVSNESSGRSEYVWNRTLEFEISICDLPRMARLCFAIYAVMDKVKKQKSTKNAQMNKYQ
TIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHTWSSFPDELEEMLNPIGTIQTNPYTE
NATALHIRFPEYSTHPVIFPPFDKVYWFVASADSEFLEMGRGGKKFHIELKEIMERDPLS
QLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPRLHPRDALE
LLDFNYPDQYVREYAVSCLQDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLERAQTNR
KIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKL
GTIKAKNKTKEAQLKEAMMKCLRQTGFIETLSDLHSPLNPQVLLGGVNVEKCRYMDSKMK
PLWIVYHNKLLVGDTLGIIFKNGDDLRQDMLTLQILKLMDILWKEANLDLRVVPYGCLAT
GDRTGLIEVVSSADTIANIQKNSSNMAAAAAFNKDALLNWLKDKNPGDALEKAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVCSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDF
IHVIQQGKTGNTEKFGSFRQYCEDAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAHRS
>A0A8C6UUX1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neogobius melanostomus|TrEMBL
MSPGKYGMQEEWEKEEAWDQGIMMDFLLPTGIFLKFPVSRNDTIKTIKKMVWKNAKSEAL
FSALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQIS
LLIGKGLHEFEAQKNHEVNEFRTKMRAFCEEKALERQLLPWRLWMEYSFPCDLEPCCSPH
EEGNNKKKNTKIFVNIKFEASEESFMLQQDPQDLPMALVKSALKKKATVFRSVRQEPEDY
TLQVNGRWDFIYGDHPLCQFKYMFSCLRNGQAPQLTMVHHSTISKYQEEQGRMSNQLFQS
RSLSRPPPLPLKKNTSSLWSINEPFYIQLLHGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVRSEPLWDQKLEFDISVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKRADCPI
AWVNTMVFDYKDQLKTGEFLLSAWPSVPGTNRLILSKSVSTASSTAPVSACSGLKNPVWH
VALAHILSVRDFLEFQLLRLKEIMDNKNYTEFFEDEKELLWKLRYEVRERYPESLSKLLL
ITKWNKREEVVLMVSLLRNWPDLPAIQALELLDYSFPDPSVRSFTIRCLKKLSDPELLQC
LIQLVQVLKYESYLDCDLTTFLLERALSNQRIGHFLFWHLRSEIHVSSVGLRFGLILEAY
CRGNIHHIKLLTKQNEALTKMKALSDIVKSGSHKMTVDDLKLCIRQESYMEALSDLLSPL
NPSIILTQICADKCRFMDSKMKPLWMMYRNPCFQGEMVGIIFKNGDDLRQDMLTLQMIHL
MENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALL
NWLKSKNPGDRLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFL
GNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEWAYKILCHNGILFVN
LFAMMKAAGLPELTSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMH
SLAKDNRP
>A0A8C6UV44|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neogobius melanostomus|TrEMBL
MCFKLFSVSRQLLWKQAQSFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFL
PVLKLITRNCGRAERLLDSKIGVLIGKGLHELDAINDQEVKDFRGKTLRQSEEKMQKVQM
MSCTEWLQASFSQQLEPGPGPDQINGVSDRSTDLKVTIHFDQSQDSASLKVPLSCTPPEL
MDMAVRKWLTTHGPEKEASRGQYFLRVSHSLEFLCGDDPLSHYKYIRTCVQTKEPPHLTL
VHSSIIQEMFDKEVSAIGAFNVILCCHFLLQHIQTCVWDVSSPFKIVLVNASKVNAEETA
KVQVRAGLFHGESSGRSEHTWRDSTLEFEISVCDLPRMTRLCIAIYAVMDKVKKQKSTKN
THINKYQTIRKSGKVLYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTV
QTNPYTENATALHISFPEYLPHAIVFPPFDKILEKAAQIARASDCSPMGRGGKKFHIELK
EIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQVLLQIWP
KLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTHF
LLERAQRNRKIGHFLFWHLRSELHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSKL
KSVNELIKFGTMKNARSKAKEAMLTKEAMMTCLRQSGYYETLSDIHSPLNPNILLAEVNV
ERCRYMDSKMKPLWIVYNNKLLDGDTLGIIFKYGDDLRQDMLTLQILRLMDLLWKEANLD
LRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDA
LDHAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKR
ERVPFILTHDFIHVIQQGKTGYTEKFASFRQYCEEAYLILRRNGNLFITLFALMLTAGLP
ELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C6T1P6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neogobius melanostomus|TrEMBL
MPPRPSSGELWGIHLMILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHQLLQ
EETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGM
PVIEFELVKDSEVQDFRRNILNVCKDSVELRDSSGPHSRALYVYPPNVESSQELPKHIYS
KLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLKMCV
QEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNMMLMAKDSLYTQLPTDTFV
MPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGIYHG
GEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDVPRAARLCLSICSVKGRKGAKEEHCPLA
WGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHFSSP
VKYPDMNAVEDHANWTISRELGFNCNFSGQSNRVARDHALTESDSEQLRQLSNRDPLSEI
TEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAMELLD
CNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRI
GHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEK
KDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLWLNW
ENPDIMSEMLFQNNEIIFKTEMDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGL
IEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRSCAGYCVA
TFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLMVISKG
SQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLA
LEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>T1DJP9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crotalus horridus|TrEMBL
MPPRPSSGELWGMHLMPPKILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVELRDANAPHSRALYVCPPNIESSDLPKHI
YNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLKL
CVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMTKESLYAQLPLDT
FAMPSYSRRISTATPYMNGEASAKSLWAINSHLRIKILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLQYEMLVLDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFS
SPVKFPDMSVIEEHANWIISREQGFNYNHAGLSNRIARDNELRDNDKEQLRAICTRDPLS
EITEQEKDFLWSHRHYCVSMPEILPKLLLSVKWNSRDEVTQMYCLVKDWPQIRPEQAMEL
LDCNYPDPMVRAFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQ
RIGHFFFWHLKSEMHNKNVSQRFGLLLDSYCRACGMYLKHLSRQVEAMEKLINLTDILKQ
EKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLWL
NWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSI
GDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDPAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKNDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAY
IRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A1S3MZ02|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo salar|TrEMBL
MEQQVSDEEPQPVVLREQIRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTLLL
EVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQTL
DCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRKNELSDRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSIDD
TPVQVLQTFFTKISNKRALLGVPEDVCEGDYVLRVCGREEYIYGNHPVRDFHWVRQCLKN
GEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDCHR
KFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQDRTSSKAFTEEVLWNTWLEFNIR
IRDLPKGARLSLQVSCGKAQTQISKGTSSSYQDNGGSPGGGSSGSHDGSKTKSRLLYYVN
LLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAIAILLDKYCY
PVALPKSREGKVAGGEGREAEGGERGQREMPNHLRKQFEAIVETDPLHPLSQEDKELLWH
FRQECMRHPRAYPKLLGSVLWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSD
AHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFW
FLRSEITQSMHYQQRYAVLLEAYLRGCGEDMLQDFRCQVEITEALQKVTREIKAMSAEKY
DVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKR
ADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIG
MIEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCV
ATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGT
SGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTV
GRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGGDKRSS
>A0A094KXR0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Antrostomus carolinensis|TrEMBL
SRMPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVLWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELVDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWMAWMEYNFPLQLEPAAKGL
GTGALHTHNKNIFVNVKFHFTFQISPAEFPITLMSYAIKKQATVFRHETVENPGDYTLQV
NGKCEYLYGNYPLYQFQYIRSCLHKGLTPHLTMVHSSTIIAMRDEQTNCIASPLKMPAKP
PPLPKKKPNYGSLWSLEQSFSIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSEV
NVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWVNV
MLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVASHPV
YYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIRD
QYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSL
KKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAV
ALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCMK
QETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNG
DDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNK
SNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCE
KAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNE
ALRESWKTKVNWLAHNVSKDNR
>A0A7L1V993|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sitta europaea|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYINLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETLQRPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLREILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKTKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A093HTA4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tyto alba|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRSCVMNRTLPQLTLIECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRTITSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHIWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>F7GAP5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ornithorhynchus anatinus|TrEMBL
MMPPAMADVLDIWAVDSQIAHDGPITVDFLLPTGVYVQLDVPREAPISSIKQMLWKQVHN
YPLFSLLTEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSK
IGVLIGKGLHEFDALEDPEVNDFRSKMRQISEAKIQSLVGLSWMDWLKHTYPPEQEASIL
ENIEDKLYGGHLVVAVHFENCQDVFSFQVSPNMNPLKLNELAIRKRLTIHGKEDEVNPYD
YVLQVSGKLEYVFGDDPLIQFQYIRKCVMNRTLPQLTLVECCNIKKMCEQEMIAIEAAIN
RNSSNLPLPLPPKKTRVVSSVWENSNPFQIVLVKGSKLNTEETVKVHVRAGLFHGTELLC
KPVVSSEIAGRNDHVWSETLEFDINICDLPRMARLCFAVYAVMDKAKTKKSTKAINPSKY
QTIRKAGKVHYPVAWVNTMVFDFKGQLKTGDIILHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIKFPENKRQPYYYPPFDKIIEKAAEIASSDSGNMASRGGKKFHVVLKEIMERD
PLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWPKLPPRE
ALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERAL
ANRRIGQFLFWHLRSEVHIPAISVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSL
MKLNAVKLSRAKGKEAMHSCLKQNAYREALSDLQSPLNPCVILSELYIEKCKYMDSKMKP
LWIVYNNKVFGGDPVGIIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATG
DRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSC
AGYCVASYVLGIGDRHSDNIMVRKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFI
HVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKSDEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6P4X3Q2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera pardus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A452E4F8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Capra hircus|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASLNSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPRLYAMHPWVTSKPLPEYLLKKITNNCVFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A1S3GMG3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dipodomys ordii|TrEMBL
MSPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHHAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRVKMRQFCEEAAVHRQQLGWEAWLQYSFPLQLEPSSRSWGA
GSPRTPNRTLLVNVKFEGSEESFTFQVSSKDKPVALMACALRKKATVFRQRLAERPEDYA
LRVNGKQEYLYGSHALCQFQYICSCLHSGRTPHLTMVHSSTILAMRDEQSNPTPQVQKPR
TKPPPIPAKKPSSVSLWSLEQAFCVELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSS
SEVSVSSEPVWQQRLEFDISVCDLPRMARLCFALYAVVEKTKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGEHCLYMWPSVPDEKGELLNPVGTVRSNPNTESAATLLICLPEVSP
HPVYYPALEKILELGRPGERMRATEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVLE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELSHYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGCTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMR
QDAYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSNEEAGSAGNVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRGYC
EKAYSILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWMAHNVSKDNRQ
>H0VNQ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cavia porcellus|TrEMBL
MELENAEPPVILREDNLRRRRRMKPRSAAASLSATELVPIEFVLPTSQRHCKTPETVLLH
VAGHGNVEQMKAQVWLRALETSTAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHAPSEETLAFQRQLTALMGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVASRDAKLYAMHPWVTSKPLPEYLSKKITNNCIFIIIHRSTTSQTIKVSADDT
PAAILQSFFTKMAKKKSLMDIPESQSERDFVLRVCGRDEYLVGDTPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPILPRNTDLTVFVEANIQHGQQVLCQRRTSAKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPGLSESRGKAQLLYYVNLLLIDHRFLLRHGEYVLHMWQISGK
GADQGSVNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTADPEGDRVRAEMPNQ
LRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGEQETVAKTYQL
LARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFE
PYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGAAMLQ
DLSQQVHVIEMLQRVTIEIKSLSAEKYDVSAQVISQLKQKLENLQNSNLPKSFRVPYDPG
LKAGPLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRI
MESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHW
LKEKCPIEEKFQTAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILG
NYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVKAYLALRHHTNLLIIL
FSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHL
VLGIKQGEKHSA
>A0A671SZ51|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPAKTDQLDLWAESGLDGDVQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSCGEWLRSCYSTQLGTGSLE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDY
VLRVSGRFEFLFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLAR
KTSNPPLPLPPKKRPPTQLHTCVWKVHSLFRINLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSP
RDALELLDFNYPDQYVREFAVICLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLER
AQSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVS
ELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLQSPLNPNILLAGVHVERCKYMDS
KMKPLWIVYNNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGC
LATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
HDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A6P8UIB2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gymnodraco acuticeps|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVEMRDASGPHSRALYVYPPNIESTQELPKH
IESKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYSQLPTD
NFVMPSYSRRISTATSYMNGEASAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSLVKYPEMNAVEDHANWTISRELGFNYNLSGQSNRSARDHALTDSDTEQMRQLSNRDAL
SEITEQEKDFLWRHRHYCMNIPEILPKILLSVKWNSRDEVAQMYCLLKEWPSTRPEQAME
LLDCNYPDPMVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDLAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A4X1TEM2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MCFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDYPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSIGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6P8PHI3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCIPNGMIVTLECLREATLLGIKHNLFKEARKYPLFH
LLQDESSYIFVGVTQEAEREEFYDETRRLCDLRLFQPILKVIEPVGNREEKILNREIGFA
IGMPICEFEMVKDPEVQEFRRNILSVCKEALDLREASGPHSQALYVYPPNVESTPELPKH
IYNKLDKGLIIVTIWVIVFPNNDKQKYTLKIPHDCLPEQVIADAIRKKTRSMHLSPEQLK
LCVQEYQGKYILKVCGCDEYLLEKYPFSQYKYIRNCITIGRLPHLMLMSKESLYGQLPAN
IFIMPSYARRSVTSCYMNGDVPTKSLWSINSLLRIRILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYLTDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINLFDYKDTLVAGKMALNLWPVPHGLEDLLNPIGVGGSNPNKETPCLELEFSWYT
HAVKFPDTPQIEEHANWSMSRELGLNYCLVGLSNRLARDSSLIENEMEQLRNICNRDPLS
EITEQEKDFLWRHRHYCINIPETLPKLLLSVKWNSRDEVTQMYCLLREWPLIKPELSLEL
LDCNFPDPMVREFALKCLVKGLTDDKLSQYLIQLVQVLKYEQYLDNILARFLIKKALTNQ
RIGHFFFWHLKSEMHSKTVSQRFGLMLEAFCRGCGMYLKHLNRQVEAMEKLINLTDILKQ
EKKDETQKMQMKFLMEQMRRPAYMEALQGFICPLNPVHQLGNLRLEECRIMSSAKRPLWL
NWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIRIMENMWQNQGLDLRMLPYGCLSI
GDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWLKDKNKGEGYDAAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQVRKRKDAMLFHIDFGHFLDHKKKKFGYKRERVP
FVLTQDFLIVISKGIQECTKTKEFERRFQEMCYKAYLVIRQQANLFINLFSMMLGSGMPE
LQSFDDIAYLRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPLSEAGH
D
>A0A0N8K1F8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MEQEVCNDDQPVVFREENKRRRRKMKAFTSSVFKMTDLITVEFVLPTSPKTGKGFDSLQL
DVAGNCTVEQVKAQVWVKAIATNLCPEFYQKYSPDHCILLYQKKGNWYEIYDKHQVFQTL
DCICYWKTLKKEVGKIHLTIRPQLSEESIQYQKYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRKNELLTRDPKIYSMDPWITTKPLPEYLLSKISKNHILLVIHRNTSSHTVKVSIDD
TPNQVLQSFFTKIAKKRALLGIPEEVSESDFVLRVCGREEYIYGNYAIKDFHWIRQCLKN
GDEIHLVLETAPDPEQDVVHKEDWSQVDICTGLAATHEQLTIDEKDHEKVFTISLWDCNR
KFRVKILGIDIPTLPRNSELIVFVEASIFHGQQLLAQEKTCPKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTQPSKTAYPDSASHESKSKSRLLYYVNLLLVDHRSLLR
QGEYVLHMWKMPEKTEDLGSINADKLTSATNPDKGNSMAIAIMLDKYGYPVALPMSTEPS
ESSEGEDDERGHREMPSHLRKQLEQIVATDPLYPLSPEDKELLWHFRQECLRIPRAYPKF
LSSVKWGSQEAVLITHQLLARSSSWNQSPLDVGLAMQLLDCHFSDAMVRSLAVRKLEKLC
DDDVLRYLLQLVQAVKFEPYHDSALAQFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQR
YAVILEAYLRGCGDAMLQDFRKQVEITEALQKVTREIKAMSVEKYDVSVQVVFQLRQKLE
NLQTSGLPESFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFRRADPTTLSSDTIGIIF
KDGDDLRQDMLILQILLIMESIWEAESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQ
QSTVGNTGAFKDEILNQWLRENCPTDDKFEQAVERFVYSCAGYCVATFVLGIGDRHNDNI
MITESGSLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTTGKKSSPHFQKFQDV
CVKAYLALRHHTNMLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGRSEEEAQRHFLDQI
EICRDKGWTVQFNWFLHLVLGIKQGGEKRSA
>A0A8D0WQF3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPGVDCPMEFWTKEENQSVDVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSDPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNRHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYAILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>F1QZY0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Danio rerio|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSPDLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKIAHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGLQHTPEGAAAVRNIRQRQHQRHRQDLRQDRNISRRRTAV
>A0A8C0MME4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYCFPLQLEPSARSWGP
GTLRVPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMR
QEAYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKFGRSWGFMRVVSPKPLFGAWS
MQNEAAPSLPLELVSNAEDKATCLPPLPQGAETSWLELASHFDGLSGVGKDRGGGSKALP
SEV
>A0A3Q0D5N6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mesocricetus auratus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVDDFRTKMRQFCEEVAAHRQQLGWEDWLQYSFPLQLEPSARSWRA
GILRVANRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEDYA
LRVNGRHEYLYGNYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPAKKPSSVSLWSLEQPFCIELMEGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAP
HPVYFPALEKILELGRHGERGHITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQLSQMLYLLCSWPELPVLSALELLDFSFPDSYVGSFAI
KSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHM
CMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGRAGSVGIM
FKNGDDLRQDTLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANI
QLNKSNMAATAAFNKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFR
GYCERAYTILRRHGQLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRV
KFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A1U8BMD4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mesocricetus auratus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
SFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN
>B7QJF5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ixodes scapularis|TrEMBL
VDCLMPTGIIIPLDCARDATLESIKDNLWDIAQKYPLFNRLGDPSSYIFVSITRDAEKEE
FYDESRRLCDLHLFHPLLKIIYVRTGIYHGTESLCPFRDTQHVAHSNPKWDEQLEFDMYI
PDIPRSARLCVSICAVYHAQEEGGEPLLRFLSHHFAPDRFRYQSYFMSSDLYLCPFRDTQ
HVAHSNPKWDEQLEFDMYIPDIPRSARLCVSICADPSSWSENDKELVQEIIRRDPLSEIS
EQEKMLLWKMRYYCCSVPDSLPKLLDAHKWNSRDHVAQARNFVFLFSRGFSLYKLLKSWQ
QVSPETALELLDCKYADMFVRKYAVAWLDVSLSDELLSQYLLQLVQERLKFLMEQFSKPD
FLEALQNFPSPLNNSCILGDLIVADCKILDSAKKPLWLLWKNPDHLAEQILDHHEIIFKN
GDDLRQDMLTLQVIRIMDSIWQKEGLDLRMMPYACLSTGKQVGMIEVVRNAKTVMNIQKK
GGRMAAFQVDSTQLHKWIREKNKRERYKQAIETFTLSCAGYCVATFILGIGDRNPDNIMV
NEEGQIFHIDFGHFLGHFKKKFGINRERVPFVLTEDFLHVEKSEEQALEYFQNQFFEAYG
GAWTTKVDWFFHSVKHF
>A0A671G512|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinolophus ferrumequinum|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRLPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A498NPR8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Labeo rohita|TrEMBL
MILMDTTSSSAEKDRTKEETPPERGPDKSDPTQKPPYSYVALIAMAIRESSEKRLTLSGI
YQYIISKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEK
GNYRRRRRMKRPFRPPPTHFQPGKSLFGGDGYGYLSPPKYLQSGFINNSWSPAPMPYTSC
QISSGNMREDGRQIEGYSGALGRCRILFILSWSRLRNNRLQRQQLLWKEAQTYPLFSLLG
EMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKIGVLIGK
GLHELDALQDQEVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQVETGSLENLIDKH
EGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHSPEEDIGTRSDYVLRISG
KLEFLFEDHPLNQYKQLHTCVWKVHSLFRINLVKGNKVNAEDAAKIQVRAGLFHGTELLC
KTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKY
QTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYT
ENATELHISFPEYSTQPVVFPPFDKGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLR
YDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREF
AVNCLRDMSDNELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRQVS
EMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKLGTIKTKTKQAHL
KEAMMTCLRQTGFIETLSDLHSPLNPNILLAGVHVERCKYMDSKMKPLWIVYNNKLLGGD
TVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSAD
TIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIG
DRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEK
FGNFRQYCEDAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDDEAL
KQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A6I9XCL8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Thamnophis sirtalis|TrEMBL
MPPRPSSGELWGMHLMPPKILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVELRDANAPHSRALYVCPPNIESSDLPKHI
YNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLKL
CVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMTKESLYAQLPLDT
FAMPSYSRRISTATPYMNGEASAKSLWAINSHLRIKILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLQYEMLVLDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFS
SPVKFPDMSVIEEHANWIISREQGFNYNHAGLSNRIARDNELRDNDKEQLRAICTRDPLS
EITEQEKDFLWSHRHYCVSMPEILPKLLLSVKWNSRDEVAQMYCLIKDWPQIRPEQAMEL
LDCNYPDPMMRAFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDSLLVRFLLKKALTNQ
RIGHFFFWHLKSEMHNKNVSQRFGLLLDSYCRACGMYLKHLSRQVEAMEKLINLTDILKQ
EKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLWL
NWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSI
GDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDPAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAY
IRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A0Q3T580|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amazona aestiva|TrEMBL
MGEADPGQAAGPDLGEAPRKPPYTYVALIAMAIRASPEQRLPLSGIYAYIAGRFPYYRCC
PKGWKNSSLQNREPHSLVLSQCDXTLYPKIIEGAIAHYQEVLLLYQRQGGSXEVSRMPPG
IYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYHMLSD
PEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLLIGKG
LHEFDSVQDPEESFTFQISPNEFPITLMSYAIKKQATVFRHETVEKPEDYTLQVNGKXEY
LYGNYPLYXFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKTAAKPPPLPKK
KPNYGSLWSLEQSFYIQLVQGSKVNADEGMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEP
VWQQRLDFDINICDLPRMARLCFALYAVIEKAKXARSTKKKSKKADCPIAWVNVMLFDYK
DQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAAXVICFPSVASHPVYYPSFE
QLLELGRNGEQPRAAAEDPEEKLQLKEILERRSHTELYEHEXDLVWKMRYDIRDQYPQAL
AKLLXITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAVNSLKKLTDH
DVFQYLLQLVQVLKYESYLDCELTKXLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGL
ILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMMHVCMKQETYLE
ALSHLQSPLXPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQD
MLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMQSDTIANIQLNKSNMVAT
AAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQV
XGLAAAVEAPEEGQGCYLAMDRYIPVQS
>Q4TAT6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tetraodon nigroviridis|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGTQRRLLFSATALACPERSSPPPPPPPLPTPA
DPSSSPPPPPPPPGMMVSLECLRETPLVSIKQQLFSEARKFPLHHLLQEESCYIFVGVTQ
EAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFAIGMPVCEFEMLKDPE
VQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNLESSPQLPQHIYSKLDKGRLIVTIW
VIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLRLCVQEYQGQYILKVC
GCDEYLLEKYPLSQYKYIRSCITVGRLPHLMLVSKDSLYSQLPASGFVTPSYSRRTPQPS
PCPGGGDGSPPRSLWAFNTPLRVRLLCATYVNVNIRDIDKVRWRYGVGVSGVGVTAALTS
SSLQIYVRTGIYHGGEPLCDNVNTQRVPCSNPRQHTRSHHRAGRGREWNEWLTYDIYLAD
LPRSARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYKDILVSGKVALSLWPVPHGLENA
LNPIGVAVQTPTRRRPAWSWSSPGLTRRWCSYEQRSKRRMTSERVEHHASTRLACDSSVS
AGDAEQLRSLCSRDPLYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMY
CLLKEWSLMEPELALELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVRLHPQS
PHLRPKGRLQPEGTDCFQVLKYEMYLDNPLARFLIKKSLTNQRIGHFFFWHLKSEMHNKT
VSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQKTQMKFLVEHM
SRPDYMDALQGFVSPLNPVHQLGNLSEAPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQ
DMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVKNSFTIMQIQCKGGLKGA
LQFNSNTLHHWLKDKNRGEAYDRAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQL
FHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQESTKTKEFERSPLSHLSGGV
VRFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKSQQEALE
YFTKQMNDAHHGGWSTKMDWIFHTIR
>A0A671SGY8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPSAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYTMPLEAGSLE
SLIDKHEDVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGFRSDY
VLRVSGKLEFLFEDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIGSVIAR
KTSNPPLLLPPKKRLPTLHTCVWKVHSLFRINLVKGNKVNAEDAAKVRAGLFHGTELLCK
TAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQ
TIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHYELEEMLNPIGTIQTNPYTENATELH
ISFPEYSTQPVVFPVFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMERDPLSQLCE
NEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDF
NYPDQYVREFAVYCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGH
FLFWHLRSEMFMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFGTIK
TKTKQAHLKEAMMTYLCVVERCKYMDSKMKPLWIVYNNKLLEGETVGIIFKNGDDLRQDM
LTLQILRLMDLLWKEANLDLRIVPYGCLATGDHAGLIEVVSSADTIANIQKTSSNMAAAA
AFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLF
HIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILR
KNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWT
TKVNWMAHIVAHPS
>Q4SSV6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tetraodon nigroviridis|TrEMBL
DHSRRRRRKKAISSASRSSMDQISVEFVLPSGARGKSGSDKLLLDVAANWTVEQVKTQVW
LRAVTLNVCPDFYQRFSPDQCILLYQKKGSVCEIYDKQQVFQTLDCVCYWRALKKDVGRI
QLVLRPQQLDESRQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPRRIELADRDPKL
YSMDPWVTGKPLPEHLLSKVSNGYILAVIHIGTVSQTIKVCIQDSPAQVLASFFAKTSNK
RVLLGIPENVCEADFVLRVCGREEYLYGDKPLQDFNWIRQCLKNGEDIHLVLESPPNPDL
DLVQKEDWAQVDDCTGAAGTHEQLTIDGKDHERVFTISMWDCNRRFRVKVLGIDIPSLPK
IPDFVVFVEASIFHGQQLLAQERTSSKTFTEEVLWNCWLEFNIKIKDLPKGARLSLQVVC
RKQAQTPNSKAGSAHQDSAASPGSHDGKAKSRLLYYVNLLLVDHRSLLRQGEFILHMWKM
PEKSEESGSGSVNADKLTSATNPDRVSSMAIAVLLDKYCCPVVLPKSRAARGGGEEAAGG
ERGRREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECTRDPRCPPPHVDPRPPSP
GRPSLTRVVLSRAYPKLLSSVRWGRQEDVSETHRLLERSSAWDSSRLDVGLALQLLDCHF
SDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSSLVRFLLKRALRSKRIGHFL
FWFLRSEIAQSMHYQQRFAVLLEAYLRGCGEDMLQDFRKQVEITEALQKVTREIKAVSAE
KYDITAQVVFQLRQKLEALQSSGLPEDFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQF
KRADGSTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNR
IGMIEIVKDATTIANIQQSVVGSTGAFKDEILCQWLRDKCVSEDKETSSTSTLATSWGTI
RVSWESVRNGFPSFSRQTSCMSWEPRERKAAPTSRNSRTCASRLISLFGITQTCSSSSSP
MMLNDRHAAADEQGGHRVHQGGADSGPQRRRGARHLLDQIEICREKGWMVQINWFVHLVL
GIKQGVEKRSI
>A0A3B5L8I9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xiphophorus couchianus|TrEMBL
MPPGKYGTQEEWEQDGDQEIFMDFLLPTGIFLKFPVSRNDTIRNIKKMVWKNASREAMFC
GLRDPDLYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNTQISLL
IGKGLHEFEAQKNHEVDEFRTKMRTFCEEKSLDRQNLPWQRWMEYSFPCELEPCSSPAAG
GSSKSKHGKKLFVNVKFESSDESFMLQQDSQDLPVALMKSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGQHPLGQFKYIFSCLRNGQNPQLTMVHHCTISKYQEDQGRVCSQMYKTR
SLSRPPPLPLKKLVVQAGLFHGSELLCKMMTSSEVTVCSEPSWDQRLEFDINVSDLPRMS
RLCFALYAIIEKTKKPRGTKKKNKKADCPIAWVNTMLFDYKDQLKTGEFLLSMWPSVPDD
KSDLLNPMGTVQRNPNVDSAAGLLIRFPNIRPHPLYYPPLDKVYLKLKEIMDNKNYTEFF
EDEKELLWKLRAEVRDYFPECLSKLLLITKWNKREDVAQMVGLLKSWPELPAIHALELLD
YSFPDPAVRSFTIRCLKKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIG
HFLFWHLKSEIHVASVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDIVKTGSQ
KMTVDDLKLCIRQESYLEALSDLLSPLNPSVILFEICTDKCRFMDSKMKPLWLMYKNPLE
QADMVGIIFKNGDDLRQDMLTLQMIRLMENLWKKEGLDLRDKLDQAIEEFTLSCAGYCVA
TYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQG
RTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELSSSKDIQYLKDSLALG
KSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A2I4KAQ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tachysurus fulvidraco|TrEMBL
MEQQVSDDESPVVLRGENRRRRRKMKAFTSNTSATMDHLTVEFVLPTTNKTTKNPDTLQL
DVIGNWTVEQVKAQLWLKAVTTNMCPEFYQKYSPDHCILLYQKKGSCCEIYDKHQVFQTL
DCIRYWKALKKEVGKIYLVLRPQLSEESIQYQKFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTTRKIELADRDPRFYSMDPWITTKSLPDYMLSKISNNNILLVIHRETSSQTIKVSIDD
TPFHILQSFFIKTVNKRALLGIPEDVNESDFVLRVCGREEYLFGDYPIKDFHWIRQCLKS
GEEIHLVLESPPDPEQDVVPKEDWAQVDDCTGVAGTHEQLTINEKDHEKVFTVSLWDCNR
KFRVKILGIDIPVLPCNSELMVFVEASIFHGQQLLAQERTPLKPFTEEVLWNIWLDFNIK
IKDLPKGARLNLQVLCGKAQTQPSRDSSSLDSKNKSRLLYYVNLLVVDHRSLLRQGEFIL
HMWKMPEKSEDNSSVNADKLTSATNPDKTSSMAIAVLLDKYCYPVALPKSRDSQNTSEME
GERGTREMPNHLRKQFDQIMATDPLHPLSVEDKELLWHFRQECVRHPSAYPKFLGSVKWG
KQEAVMATHHLLERSTAWDRSPPDVGLAMQLLDCHFSDANVRTMAVRKLETFGDDDVLRY
LLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEA
YLRGCGDAMLQDFSKQVEITEALQKVTREIKAISAEKYDVSAQVVFLLRQKLESLQMQGL
PKSFKVPYDPGLRAGSLVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLR
QDMLILQILLIMESIWETESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNT
GAFKDEILNQWLRDKCVNEDKYQQAVERFVYSCGGYCVATYVLGIGDRHNDNIMITESGN
LFHIDFGHILGNYKSFLGITKERVPFVLTPDFLYVMGTTGKKSSPNFIMFQDICLKAYLA
LRHHSNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGCTEDVAQRHFLDQIEICRDKG
WTVQFNWSLHLVLRIKQGVEKRSA
>A0A6P6PK20|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carassius auratus|TrEMBL
MEHQASDDEPPVVRREENKRRRRKMKAFTSASAVSTDQIAVEFVLPTSDKNSKDSDTLHL
DVTGNWTVEQLKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVVRTQPSEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDPKLYSTDPWITSKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQNFFNKITKKRALLGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKN
GEEIHLVLEHPLDPEQDVVQKEEWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSEMIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKESSMAVAILLDKYCYPVALPKSKDSPDSEMEGERG
QREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEA
VAITHCLLERSTMWDRSSLDVGLALQLLDCHFSDENVRTLAVRKLETLEDDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRG
CGEAMLQDLRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQMRQKLECLQTSGLPDSF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSHDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLREKCVNEEKFQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFLGISKERVPFVLTPDFLYVMCTTGKKSSPNFLQFQNVCLKAYLALRHH
TNLLIILFSMMLMTGMPQLSSKEDIEYIREALTVGQSEDEAKQHFLDQIEICRDKGWTVQ
FNWFLHLVLGIKQGVEKRST
>A0A2K5PUZ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cebus imitator|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLNGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRTKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPAKKPSSVSLWSLDQPFCIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDISISDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLHMWPSVPDEKGELLNP
TGTVRSNPNTDSAAALLICLPEVAPYPVYYPPLEKGGMLLASGGWRPELLWLSLYAWDSA
PSRMIGVETPCLGIPPGLCLLQILELGRHSECIRVTEEEQLQLREILERRGCGELYEHEK
DLLWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLGALELLDFSFP
DCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLF
WHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPK
PQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEA
GSSGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVV
LRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYV
LGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTN
NSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTE
EEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3B5A7C5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Stegastes partitus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRLSEERMQRVQLMTCTEWLQACFSPQLEPA
AGTAITDGVNDRPADLKVIIHFDQSQDSASLKVPSSSTPTELMEMALRKWLTTHRPEEEA
WKGQYMLRVSHCLDFLCGNHPLIQYKYIRTCLQAKDPPRLTLVHTSTVKAMFEKEICAIG
AVVSRKSSNPPLPLPPKRRVPTQVQTCVWDVSSPFKIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESSGRSDHTWKDSTLEFDISVCDLPRMTRLCIAIYAVMDKVKKQKST
KNAHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATELHIHFPEYSSHAIVFPPFDKILEKAAEIAKASDCAPIGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLSPRDALELLDFNYPDQYVREYAVCCLRDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALS
KLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGI
NVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAN
LDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSG
DALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A2K5PV15|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cebus imitator|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLNGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRTKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVRPVRPSVPWAPAPSSVSLWSLDQPFCIELIQGSKVNADE
RMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDISISDLPRMARLCFALYAV
IEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLHMWPSVPDEKGELLNPTG
TVRSNPNTDSAAALLICLPEVAPYPVYYPPLEKGGMLLASGGWRPELLWLSLYAWDSAPS
RMIGVETPCLGIPPGLCLLQILELGRHSECIRVTEEEQLQLREILERRGCGELYEHEKDL
LWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLGALELLDFSFPDC
HVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWH
LRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQ
TKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGS
SGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLR
SDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLG
IGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNS
EKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEE
ALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L0F7T3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Corythaixoides concolor|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSTLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKGQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKIGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDSPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLRDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A803XTI5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Meleagris gallopavo|TrEMBL
FCFMSRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQ
YEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLIN
SQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPM
AKGLGTGLLHTPTKNIFVNVKFQSGGVNFTFQISPNEFPITLMSYAVKKQATVFRHETME
NPEDYTLQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQVNSIA
NPPKMAVKPPPLPKKKTGQVPVDSWYSYFFSPQLVVQAGLFHGNEMLCKMVSSSEVNVCS
EPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVSKDCPIAWVNVM
LFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNVASHPVY
YPSFEKEICSATDSSQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLT
ITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQY
LLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAY
CRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQETYLEALSHL
QSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQ
MIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNK
DALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDF
GHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYMILRRHGP
LFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVN
WLAHNVSKDNRQ
>A0A8C7J8F3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPAMTDDLDLWAAHSQLCGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFCPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQQVQLMTWSEWLQACFSPQLEPGGG
ATPVTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISA
IGAVVNRKSSNPPLPLPPKRRGPSQVNTCVWEVSTPFKIVLIKGSKVNAEETAKVQVRAG
LFHGTELLCKPAVSSESSGRSEHVWNLTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKS
TKNAHINKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPI
GTIQTNPYTENCTALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCSTMGRGGKKFLI
ELKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQ
IWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCAL
TRFLLNRAQCNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEAL
SKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSG
IKVIWDVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLL
WKEANLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLK
EKNSGDALEKVIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFK
SKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFAL
MLTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVK
DNRS
>A0A8C7HT95|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MEQQVSDEEEPQPVVLRAEIRRRRRKMKAFTSTFSVAVDQIAVEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCVRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELSDRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVYTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNAWLEFN
IRIRDLPKGARLSLQVSCGKAQTQISKGTSSYQDNGGSPGGGGSGSHDGSKTKSRLLYYV
NLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYC
YPVALPKSRDGKAAGGEGREAEGGKRGQREMPNHLRKQFEVIVETDPLHPLSQEDKELLW
HFREECMRHPRAYPKLLGSVLWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYS
DAHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLF
WFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEK
YDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVVSGIIPIHLYSTPLLFSST
SLLACLHPFPHHHFLHPPLIVFLLLPSLLRLTLNMGPSLQIEQCKVMASKKRPLWLQFKR
ADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIG
MIEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCV
ATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGT
SGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTV
GRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A8C7JBJ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MLFRIDDLDLWAAHSQLCGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSYP
LFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFCPMLKLVTRNCGRAERLLDSKI
GVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQQVQLMTWSEWLQACFSPQLEPGGGA
TPVTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEEG
RQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISAI
GAVVNRKSSNPPLPLPPKRRGPSVSTPFKIVLIKGSKVNAEETAKVQVRAGLFHGTELLC
KPAVSSESSGRSEHVWNLTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKSTKNAHINKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPIGTIQTNPYT
ENCTALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCGKKFLIELKEIMERDPLSQLC
ENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLD
FNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLNRAQCNRNIG
HFLFWHLRSEMHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTI
KNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMDSKMKP
LWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATG
DRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKVIEEFTLSC
AGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFI
HVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A8C7CDT6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MEQQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPTEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQALQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESALNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFN
IRIRDLPKGARLSLQVSCGKTQISKGTSSYQDNGGSPVGGGSGNHDCNKTKSRLLYYVNL
LLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYP
VALPKSREGKEAGGEGREAEGGERGQREMPNHLRKQFEAIVETDPLHPLSQEDKELLWHF
REECMRHPRAYPKLLGSVRWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDA
HVRSMAVRKLETLGNDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWF
LRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYD
VSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRA
DPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGM
IEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVA
TYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTS
GKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVG
RPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A8C4BJD4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPGVFGMQDVWEKDGQQVTVEFLLPTGIYLTLEVSCSDTIGTIKKMLWRAARGEPLFGA
LSDPDAYVFTCINLTAEREDLEDEQRRLCDVRPFLPILRLVAREGDRVEKLINTQISHLI
GKGLHEFDSQKNHEVSEFRTKMRAFCEERAQERQRLPWYEWMESSFPCDLEPCSGLLKSS
KFHNFKKDLPVMLMKNALKKKATVFRPVRQEKPEDYTLQVLGRWEFIYGKHPLCQFKVTC
QLVLCKKRKLYDLRKHCWMLPVLTSFYSLFQLVVQAGLFHGSELLCKVVTSNEVNVSSEP
LWDQKLVFDISVGDLPRMTRLCLALYAVVGTTKKARSTKKKNKRADCPLAWVNTMVFDYK
DQLKTGDFSLSAWPSVPDEKSDLLNPMGTVEKNPNIDSAAGLLIRFPNIRPHPLCYPPLD
KAGLKTPLYSDSLISMHGCLQHMKLKEIVDNKNQTEIFEDEKELLWKLRVEMRDHYPESL
SKLLLIGKWNKHEDVAQMVWLLRKWPDLPVLHALELLDYRFPDPYVRSFTIKCLRKLRDD
ELFRYLLQLVQVLKYESYLDCDLTTFLLERALSNKNIGHFLFWHLRSEMHVSSASLRFGL
ILEAYCRGNLYHIKSFMKQVTNEALNKMKALNDFVKSGSQKATRSQTIEDMKVCIRQEAY
MEALSDMLSPLSPSIILSEICTEKCKFMDSKMKPLWLMYKSKVAQADTVGIIFKNGDDLR
QDMLTLQMLELMDVLWKREGLDLRMVPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSA
ATAAFNKDALLNWLKSKNPGDKLEEAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENG
QLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYK
ILCRNGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKIFKVKFNEALRE
SWKTKVNWMMHSVAKDNR
>W5PCR6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ovis aries|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVTPTPPNPTPDPGADLAPC
LSGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGPG
TLRIPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYTL
QVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRT
KPPPIPMKKPSSVSLWSLEQPFYIELIHADERMKLVVQAGLFHGNETLCKTVSSSEVSVC
SEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLF
DYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAPHPVYYP
SLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQEHFPEAL
ARLLLVTKWNTARILLQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDD
ELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSVALRFGL
IMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVCSQKTPKPQAKELMHLCMRQETYLE
ALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKNGDDLRQ
DMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAA
TAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQ
LFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCETAYTI
LRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRES
WKTKVNWLAHNVSKDNRQ
>A0A3B3IIX4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MHPGIYGMLEEWEDGDQEINMDFLLPTGIFLKFPVSRNDTIKHIKEMVWRNARSEALFSG
LGDPDGYVFTCINQTAEREELEEEFRRIRDVKPFMCVLRLVAREGNRQEKLTNTQITQLI
GKGLHEFETQKNHEVNEFRTKMRTFCEEKALERQYLPWQRWLEYSFPCDLEPCRTPSGFG
SVKMKSSKIFINVKFEASDESFMLQQDCHDLPVALMKSALKKKATVFRSLRQEPEDYILQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPQLTMVHHSTVSRFQEEQSRMCNQMFKSRSL
SRPPPLPLKRQNTSSLWSINEPFYIQLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTS
LDVTVCSEPLWDQRLEFDINVCDLPRMSRLCFALYAVIEKTKKPKSTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSMWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRP
HPLYYPSLEKIIDFEKNGDVACTHKEEHLKLKEIMDNKHYTEFFEDEKDLLWKLRTEIRE
HYPENLSKLLLVTKWNKREDVVQMVSLLKKWPDLPAIHALELLDYSFPDPAVRSFTVRCL
RKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASV
SLRFGLILEAYCRGNIHHIKILNKQNEALAKMRALSDFVKSGSQKMTVEDLKLCIRQETY
MEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNPSTPGDMVGIIFKNGDDLR
QDMLTLQMIQLMENMWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQLNSSNSA
ATAAFNKDALLNWLKSKNPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYK
ILCRNGMLFVNLFAMMKAAGLPELTCFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDNRA
>A0A3Q7T430|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vulpes vulpes|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRQYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8B6ZYL0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Orycteropus afer afer|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSSIKQVLWHHAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWEAWLQYSFPLQLEPTAHGWGS
GTLHIPNRVLLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPMVERPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPTPQVQKPR
TKPPPIPMKKPSSSSLWFLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSGPVWNQRLEFDISICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPMGTVRSNPNTDSAAALVICLPEVAP
HPVYYPALEKILELGRHVAHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPILSALELLDFSFPDRYVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPAV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALNKLKALNDFVKVSSQKTTKPQTKELMHVCMR
QETYLEALSHLQSPLDPSTLLADVCVEQCTFMDSKMKPLWIMYSNEEAGSEGSVGIIFKK
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRDYC
EKAYTILRRHGLLFLHLFTLMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A6J0U244|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pogona vitticeps|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNIESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMTKESLYEQLPLD
TFTMPSYSRRISTATPYMNGEASVKSLWQINSNLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLQYEMHVLDLPRAARLCLSICSVKGRKGAKEETP
CLELEFDWFSSPVKFPDMSVIEDHANRTISRELGFNYGHAGLSNRLARDNELRESDKEQL
RAICTRDPLSEITEQEKDFLWSHRHYCVNMPEILPKLLLSVKWNSRDEVSQMYCLIKDWP
YIKPEQAMELLDCNYPDPMVRAFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVR
FLLKKALTNQRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEK
LINLTDMLKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRI
MSSAKRPLWLNWENPDIMSELLFQNNEVIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDL
RMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYD
PAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRER
VPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMP
ELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7L3D2C5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pluvianellus socialis|TrEMBL
MELGDDEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEISQTTDFYNMFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKIINNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVLL
EAYLRGCGRAMLNDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLTAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSVHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8B9IS42|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amazona collaria|TrEMBL
MPVGSAAGRGDFVWCPWPSLTTGCCGCGRARALQWIFSGMELEDYEQPVVMREENKRRRR
RMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLEIAANCTVEQMKAQIWMRALEM
SQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLDCILYWKVLQKKVGKIYVVQKQ
NPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRLVTPRMIEVACRDPKLYAMHPW
TTSKPLPEYLLKKITNNNIFIIIHRGTTSQKVKVSIDDTPDMILHSFFTKMAKKKSLMDI
PEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNGEEIHLVLDNPPDPSEDEVQKE
EWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRKFRVKIIGIDIPVLPRNTDLTV
FVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKIKDLPKGALLNLQIYCGKAQGL
STKTNLQSHESPNSDPKCKTQLLYYVNLLLIDHRFLLRSGEYVLHMWKIPGKGEEQGSIN
ADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSDPQGDRIRAEMPNQLRKQLEEI
IATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQEIVAKTYQLLAKKEIWD
QSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVLHYLLQLVQGYALRIFSQVYTR
MGFLRGFLGTAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAV
ILEAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQ
SSKLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHG
DDLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQST
VGNTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMIT
ETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVK
AYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVC
RDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C5HD61|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
MDSELMQVSDEEPELLQEDSLTRRRRRRRKKAITSPSCASMDHITVEFILPTNSHGGSGP
DSLQLEVAGNWTVEQVKAQVWLKAVTLNLSFDFYQRLSPDHCILLYQKKGTVCEIYDKHQ
VFQTLDCIRYWRALKKDVGRIQLVPCPQPSDESLQYQRDLNYLIGYDVTDVSNVHDDELE
FTRRKLLTPRRIELLDRDPRLYSMDPWVTCKPLPKHLLSKVNNGHILLVIHMSTASQTIK
VSINDTPSQVLMSFFTKTANKRALLGIPDNISESDFVLRVCGREEYLYGERPLQNFNWIR
QCLKNGEEIHLVLTAPPDPAMDLVQREDWAQVDDCTGVAGTHEQLTIEEKDHERVFTISM
WDCNRKFRVKVLGIDIPALPKVPELIVFIEASIFHGQQLLAQERTTSKSFSEEVLWNCWL
EFNIKIKDLPKGARLNLQVICGKQQQPSNSKGGSFQNNHPASGSQEGKNKSRLLYYVNLL
LVDHRSLLRQGEFILHMWKMPEKSDESSSSINADKLTSATNPDKASSMAVVILLDKYCYP
VVLPKSRESVSAAKEAEGCDRGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHE
CMRDPRAYPKLLSSVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVR
SIAVRKLETLDDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSKHYQQRYAVLLEAYLRGCGGDLLTDFQKQVEMTEALQKVTREMKATSADKYDVTA
QVVFLLRQKLETLQSTGLPQSFRVPYDPGLKAGALLIEQCKVMASKKKPLWLQFRRADPT
SRSKDPIGIIFKDGDDLRQDMLILQILLIMESIWEAESLDLCLLPYGCISTGNKIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILHQWLREKCVREDKFQQAVERFLLSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLFVMGTSGKK
SSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSE
DEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKQST
>A0A2Y9JE77|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Enhydra lutris kenyoni|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8D3BCD9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETKRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNIESTPDLPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYAISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEGAAKSLWAINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDVPCAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHVLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSQVKYPEMNAVEDHANWIISRELGFNYNLSGQSNRVARDHALTDSDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPVVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QKIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8B6BRR8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mytilus galloprovincialis|TrEMBL
MPPVIVSPDLDVTSFQNDLGQLDIDFLLPNGICVPLQVDIDRPLDQIKQELWKQAANYPL
FQQLATFDKYGFLYISGEGQKEDVMDESVGISELRLAASFLKVVEKPADDKRKTIDRQIN
SLIGMKGSNYIQAQHSVSKAEISEFRQKMTTYCNNDVLKQANQDPTGLVYFEYKHPCRLR
STSELPPDVENMVIDYIVLTVIVQETGTSYKLRVKKLSTPDELVKMTVDKWSSKSGQKTI
NCNDYVLQVLGMNDFLYGDNPLVMFKYVYSCIVKNTAPEFWLKNKSSVLEKQEVSQPHKS
SRTSFQEERRNTVRSEKRSGHCVWDIHQNFYITLHTACNVQVPENCRNLVRLCVGVFHGP
DPLCSIQETKEVFVSQDGLCSFNDCINFDIKVQDLPQMSRLCFGLHCKKGKEPLLLAWAN
IPIFDYKSNLQKGKLKLPLWPRSELIQQEESYCFPVGTVATNPQGDCSMIEFSVPDFTKK
GSIYYPPIEKVLQCASDHMEEPGKCGSPVLELASTYIEAPGMPGSTTWRPNKNIVQQLDS
ILRANQYTILQTLDEQQKQLIWWMRYDIRDKCSEFPHALLYVLYSVSWDNHIEVSKMQAL
LQTWPTLEADQALTLLDFTFPDKYVRKKATEWLDELPDEELAQYLLQLVQALKYENYLNC
DLVKFLLRRALQNRNIGHKLFWLLKSDMHEPSVTVQYGLIIEIYLKANPSHMSILDRQQI
ILQKLKSITDIHTKAANLKKKAKEKDDSPLQKVMQQSAYKEAFCKIYSPITLMYKLDKIV
EKSCKVMDSKKKPFWLEWTNDDEKGQNIQLIYKCGDDLRQDMLTLQILEVMDTIWQSEGY
DLRLNPYGCVATGCEEGMIEVVQKSLTLAGIQKWRKLGLDKRSLYDWLKHKNPSEHSLQR
AVEEFKLSCAGYAVATYILGVGDRHNDNIMMKETGQLFHIDFGHFLGNKKTKFNINRERV
PFILTSHFEYIIKDGEKKPQNFTDFKEICERAYLIIRSRAHLLIQLFMMMLSSGIPQLNN
VSDIDYIKEVLALNSTQEEALEKFRKKFKEAQDNSWSTTVNWWFHMRVH
>A0A673III9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSAELPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKITHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDEYLLEKHPLSQYKYIRSCITLGRLPHLMLVSKDSLYSQLPSS
GFMAPSYSRRTPQPSPCPGGGDPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDEQQIEEHANWKCLHFTPCHTHTHTHTHTHSHKHSISQADAEQLRTLCSRD
PLYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQPGIKPHHAVMSPSSPI
TETADWLMKLILHSDWLLQTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECR
IMSSAKRPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLD
LRMLPYGCLSIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIRDKNKGEAY
DRAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRE
RVPFVLTQDFLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGM
PELQSFDDIAYLRKTLALEKNQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A4W2ILR7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos indicus x Bos taurus|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASMSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDSLWGKKKKPHAHCDLCLIPLMLLNIPSVSADVT
NVPKARKASSSFQGLLSSDSITTETHKHQVENWNLCALALICCSGSTIMNCKICLNSAHR
VNLSSTIMIACFLTEAGNNQRDSPGPLYSSP
>A0A673MMJ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQS
GKSHSGKKILVNVKFEGSEETFVLQQDPQDLPMFLKWNALRKKSTVFRSAKREKPEDYTL
QVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRTRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSCLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKVIKTTLINFFQHLKLREIVDNKNYTEFFEDEKELLWKLREEVRQRYPESL
PKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHVRSFTIRCLRILRND
ELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSLRFGL
ILEAYCRGSIFLIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYME
ALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKDKYDHVGIIFKNGDDLRQDMLT
LQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAF
NKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHI
DFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRN
GTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTK
VNWMMHSFAKDNR
>A0A444V2H5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acipenser ruthenus|TrEMBL
MPPRPSSGELWGLHLMPPRILEECSYIFVGVTQEAEREEFYDETRRLCDLRLFQPILKVI
EPVGNREEKILNREIGFAIGMPICEFELVKDPEVQDFRRCILSVCKEAMEEREGGGAHSQ
ALYVYPPNIESTPELPKHIYSKLDKGRLIVTIWVIVSPTNDKQKYTLKTPHDCLPEQVIA
EAIRKKTRSMHLSPEQLRLCLREYQGKYILKVCGCDEYMLERHPLSQYKFSFNNTDEGTG
AQTLVCLTQFSFNNTDEGTGAQTLVCLTQFSFNNTDEGTGAQTLVCLTQFSFNNTDEGTG
AQTLVCLTQFSFNNTDEGTGAQTLVCLTQFSFNNTDEGTGAQTLVCLTQFSFNNTDEGTG
AQTLVCLTQFSFNNTDEGTGAQTLVCLTQFSFNNTDEGTGAQTLVCLTQFSFNNTDEGTG
AQTLVCLTQFSFNNTDEGTGAQTLVCLTQFSFNNTDEGTGAQTLVCLTQPLLVSIRLMKA
PAWLPVPVSVLHSPS
>A0A852PEM4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Atrichornis clamosus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWRHAQHEPLFH
MLSDPEAYVFTCINQAAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRSKMCQFCEERAAKRQQLGWAAWMEYNFPLQLEPVAKGLGT
GSLQTPTKNIFVNVKFQSGGESFTFQISPREFPITLMSYAIKKQATVFRHETVQRPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQNNITSPPKAAA
KPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSSS
EVSVCSEPVWKQRLDFDINVCDLPRMARLCLALYAVIEKARKARSTKKKSKKADCPIAWV
NVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAH
PVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRFDI
RDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAIN
SLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVP
AVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMC
MKQETYREALSHLQSPLNPNIVLAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFK
NGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQL
NKSNMVATAAFNKDALLNWLKSKNPGEALDQAIEEFTLSCAGYCVATFVLGIGDRHSDNI
MVRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGY
CERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKF
NEALRESWKTKVNWLAHNVSKDNRQ
>A0A315V1Y2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gambusia affinis|TrEMBL
TKWGRATLENCSSEEELPLEGGARSTQLSSGNRRAGFAGTAMPPRPSSGELWGMHLMPPS
ILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYHLLQEESSYIFVSVTQEAER
EEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFAIGMPICEFDLVKDSEVQDF
RRNILNVCKEAVDLRDSNGCHSRALYVYPPNVESSAELPRHIYNKLDKGQIIVVIWVIVS
PSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTQEQLKMCVQEYQGKYILKVCGCDE
YLLEKYPLSQYKYIRSCIMLGRMPNLMLMSKESLYSQLPMENFTMPSYARRISTATPYMN
GETATKCLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQLCDNVNTQRVPCS
NPRWNEWLTYDMYVTEIPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTHTLVAG
KMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSCPVKFPDMSMIEDHANWN
ISRELGFNYSHPGLSNRLARDKPLTESDNEQLRQVCNRDPLSEITEQEKDFLWSHRHYCI
NIPDILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNFPDPMIREFAVKCL
EKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSEMHNKT
VSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLKQEKKDEAQKVQMKFLVEQM
KRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWENPDMMSELLFQNNEI
IFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQ
IQCKGGLKGALQFNSHALHQWLKDKNKGEMYDQAIDLFTRSCAGYCVATFILGIGDRHNS
NIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFER
FQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQEALDYF
MKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8C4WGC8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gopherus evgoodei|TrEMBL
MPPGIYCPVEFWSKEENQTIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVRDPEVNDFRAKMRQFCEEKAVKRQQLSWMTWMEYNFPLQLEPLAKGPRT
GPLRIPNKNIFVNVKFESGGESFTFQVSPKEFPVTLMSYAIKKQATVFRHQTVESPEDYT
LQVKGKCEYLYGNYPLYQFQYIRSCLHHGLMPHLTMVHFSSIIAMRDEQTNCTAHTPKMV
SKPPPLPKKKPTHESLWSLNQPFYIELVQGSKVNADERMKLVVQAGLYHGNEMLCKMVSS
AEVNVCSEPVWKQRLDFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQSNPNTESAAALVICFPSVTP
HPVYYPSFEQLLELGRNGEYTRAASEDPEEKQQLREILERRSHTELYEHEKDLVWKMRYE
IRDQYPEALAKLLIITKWNKHEDVAQMISLLRSWPELPVLNALELLDFSFPDRYVGSFTI
NSLKKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSNYHMKVLMKQGEALNKMKALNDFIKVSSQKATKPQAKEMMHV
CMKQETYLEALSNLQCPLNPTVILAEVCVDQCTFMDSKMKPLWIVFNNEEAGGRGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVLHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTTNSEKFERFRD
YCEKAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6F9AR16|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coregonus sp. 'balchen'|TrEMBL
MPPRPSSGELWGMHLMPPSIQVDFLLPNGMILTLECTREATLISVKQDLFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDAEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYIYVRTGIYHGGEQLCDN
VNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLF
DYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHFSNPSNRLARD
NPLTDSDNEQLRLVCNRDPLSEITEQEKDFLWRHRHYCVSIPEILPKILLAVKWNSRDEV
AQMYCLLKDWPAIKPEQAMELLDCNFPDPRIRDFAVKCLEKYLTDDRLSQYLIQLVQVLK
YEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLK
HLSRQVEAMEKLINLTDLLKQEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQ
LGNLRLEECRMMSSAKRPLWLNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIM
ENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQW
LKDKNRGEMYDQAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDH
KKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFIN
LFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFH
TIRQHAMN
>A0A7L0XYT8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tyrannus savana|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPVTLMSYAIKKQATVFRHETLQKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A091MTF9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acanthisitta chloris|TrEMBL
SRMPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCSASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGL
GTGSLLTSTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQNPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSAIIAMRDEQTNCITSPPK
MTAKPPPLPKKKVNGDTYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLC
KTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAD
CPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICF
PSVAAHPVYYPSFEQGLWELSKSSGLRLSPVYALSCDSHEQKLQLKEILERRSHTELYEH
EKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFS
FPDRYVGSFAINSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHF
LFWHLRSEMHVPAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKA
TKPQTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNE
ETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEV
VMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATY
VLGIGDRHSDNIMIRETGQVGQLGILH
>A0A093GPR6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dryobates pubescens|TrEMBL
SRMPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPDSYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGL
GTGPLHIPTKNIFVNIKFQSGGESFTFQISPREFPITLMSCAIKKQATVFRHETVENPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPK
MVAKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWRQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPGKKGDLLCQGHTCTLPVLHVLAQQCEQIVLVW
KVAWAVLSAWQAHTSSKNLDWLLLAWSWETQNLCSQMLKEILERRSHTELYEHEKDLVWK
MRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVG
SFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRS
EMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKE
MMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGV
GIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTI
ANIQLNKSNMVATAAFNKDALLNWLNDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGY
CEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKF
NEALRESWKTKVNWLAHNVSKDNR
>A0A3P9N152|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia reticulata|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFIEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIMSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLENFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCENVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVSLFDYMDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
RFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAADAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCLNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTISRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDRVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNHGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLMLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A7K5N5W5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chroicocephalus maculipennis|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSTNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFRKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8B7UXI7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Castor canadensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDFNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETATKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEHCP
LAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFS
SVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPLS
EITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMEL
LDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQ
RIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQ
EKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWL
NWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSI
GDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAY
IRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C8EJB2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPRPSSGELWGMHLMPPSIMVDCLLPNGMILTLECTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDAEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKAYICINLQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLKMCVQEYQGKY
ILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPIDTFTMPSYARR
ISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQLCDN
VNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLF
DYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHFSNPVKFPDMP
AIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPLSEITEQEKDF
LWRHRHYCVSIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNFPDPM
IRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWH
LKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLKQEKKDEAQKV
QMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWENPDMMS
ELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEV
VRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRSCAGYCVATFI
LGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQE
CTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDK
TEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A7M4E4Z7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crocodylus porosus|TrEMBL
MPPGIYCPVEFWSKEENQNIQVDFLLPTGIYLSLPVSCNASLGTIKEVVWQHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVPDPEVSDFRTKMRQFCEERAAKRQQLSWMAWMEYSFPLQLEPLSKGLGT
SPLHVPHKNIFVNVMFESGGESFTFQISPREYPSTLMSYAIKKQATVFRHQTVESPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHQGLMPHLTMVHYSTIIAMRDEQTNCITHPPKMG
AKPPPLPKKKPNSGSLWSLEQPFYIDLVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYSVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKAGECCLHMWSSFPDEKGELLNPMGTVQSNPNTESAAALVICFPNVLV
HPVHYPSYEQLLDLGRNGEHGRATLDDPEEKQQLKEILERRSHTELYEHEKDLMWKMRYH
IRDQYPEALAKLLIITKWNKHEDVAQMISLLQTWPELPVLSALELLDFSFPDRYVGFFTI
NSLKKLTDEELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQRATKPQTKEMMHV
CMKQETYLEALSNLLSPLNPNIILAEVCVEQCTFMDSKMKPLWIVFNNEEAGGSSVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRD
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A852IDS5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nicator chloris|TrEMBL
MDLGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSSSDAKCKTQLLYYVNLLLIDHRFLLRC
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQGI
>A0A8C9PFC2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Spermophilus dauricus|TrEMBL
MPLGIDCPMEFWTEVEKNQSVVVDFLLPTGIYLSFPVSRNANLSTIKQMLWHEAQNEPLF
HMLRDPEAYVFTCVNQTAEQQELEDKQQRLCDVQPFLPMLRLVTRQGDRMEKLINSQISL
LIGKGLHEFDCLQDPEVNDFRTKMCQFSEEAAAHRQQLGWEAWLQYSFPLQLEPSTRSWG
DSNTSQISNPDLLVNVKFEGSRESFTIQVSTKDVPLALMACALQKKAKVYQHLTMEQPED
YVLQVNGRHEYLYGSYLLCQFKYICSCLHSGQTPHLTMVHSSSILAMRDEQSKPAPQVQK
PHTKLPPIPMKKLVVQAGLFHGNEMLCKTMSSLEVSVCSEPMWKQHLEFDINICDLPRMA
RLCFALYAVMEKAKKVYSRKKKSKKEDCPIARANLMLFDYKDQLKTGELCLYMWPSMRKE
TLEVLNPMGTVHSNPNTESAVTLVIYLPEMAPHPVYYPALEKILELGHHWEHGPTTKEEK
LQLQGILEQRGSGELYEHEKDLVWKMRHEVQEHFPEALAHLLLVTKWNKHEDVAQMLYLL
CSWPELPVLNSLELLDFSFPNCHVGSFAIRSLQKLTDDELLQCLLQLVQVLKYKSYLDCE
LTQFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYFRGSTHHMKVLMKQVEA
LSKLKALSDFVKVSSQKTTKPQTKELMHLYMRQDTYLEALSHLQSPLDPSTMLAEVCVER
CTFMDSKMKPLWIMYSSEEAGSADSVGIIFKNGDDLRQDMLTLQMIQLMDALWKQEGLDL
RMTPYGCLPTGDCMGLIEVVQHSDTIANIQLNQSNLAAMAAFNKDALLNWLKSKNSGEAL
DRAIEEFTLSCARYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGIKRE
RVPFILTHDFVHMIQQGKTSDNEKFERFRGYCEQAYSILQCHGLLFLQLFALMQAAGLSE
LSSSKDIQYLKDTLALGKTEEEGLKHFRVKFNEALRESWKTKVNWLAHNLTKDNRQ
>A0A8C9PYJ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Spermophilus dauricus|TrEMBL
MPLGIDWPMEFWTEVEKNRSVVVDFLLPTGIYLSFPVSRNANLSTIKQMLWHKAQNEPLF
HMLSDPKAYVFTCVNQTAEQQELEDEQQRLCDVRPFLPMLRLVTRQGDRMEKLINSQISL
LIGKGLHEFDCLQDPEVNDFRTKMCQFSEEAAAHRQQLGWEAWLQYSFPLQLEPSTRSWG
DSNTSQISNPDLLVNVKFEGSRESFTIQVSTKDVPLALMACALQKKAKVYQHLTMEQPED
YVLQVNGRHEYLYGSYLLCQFKYICSCLHSGQTPHLTMVHSSSILAMRDEQSRPAPQVQK
PHTKPPPIPMKKPSSVSLWSLGQPFCIELIQGSKINADEQMKLVVQAGLFHGNEMLCKTI
SSLEVSVCSEPMWKQHLEFDINICDLPRMARLCFALYAVMEKAKKAYSSKKKSKKEDCPI
AWANLMLFDYKDQLKTGELCLYMWPSVPGGPRPSRERLLEGEASRTGSPTTTSLLPSDEK
GDLVLNALELLDFSFPDCHVGSFAIRSLQKLTDDELFQCLLQLVQVLKYKSYLDCELTQF
LLDRALANRKIGHFLFWHLRYSEMHVPSVALRFGLIMEAYFRGSTHHMKVLMKQVEALSK
LKALSDFVKVSSQKTTKPQTKELMHLYMRQDTYLEALSHLQSPLDPSTMLAEVCVERCTF
MDSKMKPLWIMYSSEEAGSADSVGIIFKNGDDLRQDMLTLQMIQLMDALWKQEGLDLRMT
PYGCLPTGDCMGLIEAVQHSDTIANIQLNQSNLAAMAAFNKDALLNWLKSKNPGEALDRA
IEEFTLSCARYCVATYVLGIGDRHSDNIMVRENGQLFHIDFGHFLGNFKTKFGINRERVP
FILTHDFVHVIQQGKTSDNEKFERFRGYCEQAYSILQRHGLLFLQLFTLMQAAGLPELSS
SKDIQYLKDTLALGKTEEEGLKHFRVKFNEALRESWKTKVNWLAHNLTKDNRQ
>A0A2Y9SS64|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Physeter macrocephalus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWRRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEAAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPLKKPALVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEAAP
HPVYYPALDKILELGRHGEHGRFTEEEQLQLREVLERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCLR
QETYLEALSRLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVVYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A091LL36|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cathartes aura|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWSEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEI
MERDPLCQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A091LUW2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cathartes aura|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLXXXXXXXXXXXXSFDDIAYIRKT
LALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3P9ANT2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPRPSSGELWGMHLMPPTIQVDCLLPNGMILTLECTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPVD
TFAMPSYARRISTATPYMNGETAAKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANWNISRELGFNYSHSGLSNRVARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVSIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A6Q2WU53|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPAMTDLMDMWAAHSQVSGDNLVSVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQTY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALPDQEVKDFRSKMFRISEEKMQRVQLMNWSECRWLSWHCVWAEMLC
PVDQGGLLCVCVCYEELPLSITLSSLKVCPSTTPSELMEQALRKWLTTHGPEEEGRQAQQ
YILRVSDKLEFLCGDHPLIQYKHIKACLQSKECPHLTLVQISSVKDMFEKEISAIGAVVN
RKSSNPPLPLPPKRRGPSQVNTCVWEVPLPFKIFLIKGSKVNAEETAKVQVRAGLFHGTE
LLCKPAVSSESSGRSEHVWNRMLEFDIQVSDLPRMARLCFAVYAIMDKVKKRKSTNNSHI
NKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDITLHSWSSFPDELEEMLNPIGTIQTN
PYTENATALHIQFPDYIAHPIVFPPFDKILEKAAEIARSSDCSPMGRGGKKFHIELKEIM
ERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLS
PRDALELLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLD
RGQGNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSV
NELIKLGTIKNVRSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKC
RYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRI
VPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEK
AIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERV
PFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELT
SVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A803TN68|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anolis carolinensis|TrEMBL
MLPGIYCPVEFWSKEANQSIQVDFLLPTGIYLTLSVSCNATLGTIKQLVWHHAQCEPFFH
MLSDPESYVFTCINQTAERQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLISSQISLL
IGKGLHEFDSLGDLEVDDFRVKMQHFCEERAARRQQLSWKAWMEYSFPVQLEPLANGLGG
RSLLQFPNKNIFVNVKFESGGESFTFQISPKEYPATLMSYAIKKQATVFRHQKINSPEDY
ALQINGKYEYLYGNHPLYQFQYIRDCLCRGLLPHLTMVHASSISALWEEQTNGISYPIKA
ASKAPPVPKKKPMSVSLWSLEQPYSIELVQGSKVNADERMKLVVQAGLYHGHEMLCKMVS
SSEVSVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIA
WVNVMLFDFRDQLKTGECCLPMWSSFPDEKGELLNPMGTVQTNPNTESAASLVIRFPTIS
SNPLYYPTFEQKHNECTIHSGKQQLKEILERRSHTDLYEHEKDLVWKMRHQIRDQFPHAL
AKLLVVTKWNKHEDVAQMIYLLQSWPELPVLNALELLDFSFPDRYVGAFTVNSLKKLTDA
DLFQYLLQLVQVLKYESYLDCELTKFLLGRALSNRKIGHFLFWHLSSQKNAKPQTKEFMH
TCMRQETYLEALSNLQSPLNPSVILAKVSVELCTFMDSKMKPLWIVFNNEDAGGGHVGVI
FKNGDDLRQDMLTLQMIQLMDILWKKEGLDLRDALDRAIEEFTLSCAGYCVATYVLGIGD
RHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKF
ERFREYCERAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEARR
HFQLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K9TSL7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chloroceryle aenea|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGIGT
GPLHAPTRNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAMPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDLVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDSLEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCNKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6Q2Z3G6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPTD
CFSMPSYARRISTATAYMNGETSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLAYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKVNTRDAMVHGML
SNCSVRPLRVHTHVNHIVTICRSCSYNFSNLLNALVARDHALTDIDNEQLRQVCNRDPLS
EITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMEL
LDCNYPDPMIRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTNQ
RIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQ
EKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNIRLEECRIMSSAKRPLWL
NWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLLYGCMSI
GDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAVDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGTQECTKTREFESVFPMCYI
>A0A3Q3KJU9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monopterus albus|TrEMBL
MPPGKYGMQEEWEKKGDQEIMMDFLLPTGIFLKFPVSRNDTIKNIKKLVWKNARSEALFS
ALGDPDAYVFTCINQTAEREDLEEESRRISDVQPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRSKMRTFCEEKAQERQKWPWYLWLKYSFPCDLEPCCSLPST
NSKNTKKIFVNIKFEACDESFMLQQDPQDLPVVLMKSALKKKATVFRSVRQEPKDYTLQV
NGMWDFIYGNHPLCQFKYIFSCLRNGQNPHLIMVHHSTISKYQEEQGICNQVYKSRSLSR
PPPLPLKKQNTSSLWSINEPFYIQLLQGIRVNADEGMKLVVQAGLFHGSELLCKVVTSSE
VTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVN
TMVFDYKDQLKTGEFLLSTWPSVPDEKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPYP
LYYPPLDKVSEIERNGDISIATKEEYIKLKEIMDNKNYTEFFEDEKELLWKLRAEVCNHY
PESLSKLLLITKWNKREDVVQMMSLLRSWPDLPAIHALELLDYSFPDPAVRSFTVKCLRK
LSDDELLQCLIQLVQVLKYESYLECDLTTFLLERALSNKRIGHFLFWHLRSEIHVASVSL
RFGLILEAYCRGNIHHIRGLTKQNEALGKMKALSDFVKSGSQKMTAEDLKLCIRQESYLE
ALSDLLSPLNPSIILAEICADKCRFMDSKMKPLWLMYKSPWAQRDMVGIIFKNGDDLRQD
MLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNSSNSAAT
AAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQL
FHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKIL
CRSGMLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESW
KTKVNWMMHSLAKDNRP
>A0A3B3W0V0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia latipinna|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRNSSGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKISHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLTRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEASSKSLWSINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLPYDMYIPDVPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMNAVEDHANWIISRELGFNFNLSVNHSGTQQSSRAARDHALTESDGEQMRQL
SNRDPLSEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDDVAQMYCLLKEWPSIR
PEQAMELLDCNYPDPVVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDSPLARFLL
KKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLIN
LTDILKQEKKDETQKVQMKFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLEECRIMSS
AKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRML
PYGCLSLGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGETYDLAV
DLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPF
VLTQDFLIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQ
SFDDIAYIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A7J8HUF1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rousettus aegyptiacus|TrEMBL
MPPAMADILDIWAVDSQIASDGSILVDFLLPTGIYIQLEVPREATISSIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRIKMRKLSEEKIQSLVGLSWMDWLKQTYPPEHEPSILE
NLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDEVSPCDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINR
NSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCLAVYAVLDKVKTKKSTKTMNPSKYQ
TIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIVLHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLVELKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALA
NRRIGQFLFWHLRSEVHIPAVCIQFGVILEAYCRGSVGHMKVLSKQVSTCFNLHSVCHMA
YDKLYHILFLSLTFQ
>A0A3B4TX47|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola dumerili|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRAILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGCPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVSGKVALGLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDAEQLRSLCSKDP
LYELSEQEKDFLWRHRHYSVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A8C3F0Q0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysemys picta bellii|TrEMBL
MELGNYEQPVVMREETKRRRRRMKPYSAASNLSSMELISIEFILPTSNKHTKVQETMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHKFTPDQFILQYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGKIYVVQKQNPAEAVQEFQTQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYSMHPWITSKPLPEYVFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDDPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIVGIDIPVLPRNTELTVFVEANIQHGQQLLSQRRTISKPFTEEVLWNTWVEFDIKI
KDLPKGALLNLQIYCGKAQALSTKVSLQSHDSPNSDSKCKTQLLYYVNILLIDHRSLLRS
GEYVLHMWKISGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEAIVDTDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKREAWDHSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQIIKLLHKVTMDIKSVSAEKYDVTSQVITQLKQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKDRCVIEEKFQAAVERFVYSCSGYCVATFVLGIGDRHNDNIMITES
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTAGKKTSLHFSKFQDICVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A834BV75|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias melastigma|TrEMBL
MPPAMTDLVDIWGAHSPLDGQAPVHVTMDFLLPTGIYIQMEVPREATIQHIKLLLWKQAK
SYPLSSFLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVFRLVTRNCGRAERLLD
SKIGVIIGKGLHELDGINDQEVKDFRSKMQRLSEERMQRVQMMSFSEWLQACFSPQLEPA
AGTAITDGANDWPADLKVIIHFDQSQDSTSLKVLSSCSPFVLIEIALRKWQTTHAPEEET
KKDQYILRVSQCLEFLYGDHPLIQYKYIRSCLQTKESPHLTLVHINTVKAMFDKESSAIG
AVVSRKSSNPPLPLPPKKRAPTQVQTCVWDVSSPFKVVLVKGSTVNADENAKVQVRAGLF
HGTELLCKPAVSNESSGRSNHSLENNTLEFEISVCDLPRMTRLCFAIYAIMEKVKKKSYK
NPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDMILHCWSSFPDELEEMLNPIGT
VRTNPYPENATALHIHFPEYSSHPIIFPPFDKILEKAAEIAGSSDSTPIGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVSCLRDMSDEELLQYLLQLVQVLRYEPYYDCALTH
FLLERAQRNRKIGHFLFWHLRSEIHMPAVSIQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNTRSKTKEAMLTKEAMITCLKQSGYSEALSDLHSPLNPNVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLMSSDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRVVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGYTEKFG
>A0A7L4FX80|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alopecoenas beccarii|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSNNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTADFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLIKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDDPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKMNLQSHESPNSDSKYKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRARAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEDDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A851UIY1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Elachura formosa|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDHPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDIKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAVSIVLDKYCHPVALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQEAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A4W5PDG6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MCGSTGCLVLVPAMPPAMTDDLDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQ
HIKLLLWKQAQSYPLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFCPMLKLVT
RSCGRAERLLDSKIGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWL
QDVYFFAEFRTLSAPRHLFLSSVSLSLSVCVCCVDDNVLSLQDTASLKVWPSTSPSELME
QALRKWLTTHGPEEEGRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLV
QVSSVQAMFEKEISAIGAVVNRKSSNPPLPLPPKRRGPSVTEHCSLSQSPYYGEPLVVVV
VPPQVQVRAGLFHGTELLCKPAVSSESSGRSEHVWNRTLEFDITVSDLPRMARLCFAVYA
VMDKVKKQKSTKNAHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHSWSSFP
DELEEMLNPIGTIQTNPYTENATALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCST
MVLSGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKH
EDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQV
LRYEPYYDCALTRFLLNRAQCNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYCRGSIPH
IEVLKKQVEALSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLH
SPLNPSVLLSGINVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQI
LRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKD
ALLNWLKEKNSGDALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFG
HILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNL
FITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNW
MAHNVVKDNRS
>A0A4W5JS81|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MEQQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVTMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTLFQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELSDRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPIQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPDQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFN
IRIRDLPKGARLSLQVSCGKAQTQISKGTSSYQDNGGSPVGGGSGSHDGNKTKSRLLYYV
NLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAIAILLDKYC
YPVALPKSREGKEAGGEGREAEGGEREQREMPNHLRKQFEAIVETDPLHPLSQEDKELLW
HFREECMRHPRAYPKLLGSVRWGRQEAVLTTHRLLERSSVWDRSVLDVGLAMQLLDCHYS
DAHVRSMAVRKLETLGDNDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLF
WFLRSEIAQSMHYQQRYAVLLEAYLRGCGEGMLQDFKCQVEMTEALQKVTREIKAMSAEK
YDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFK
RADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKI
GMIEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYC
VATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMG
TSGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALT
VGRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVEKRSA
>A0A060X4I3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRTKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVV
TSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKAVRYS
KWQNGGFVPLLPGVYVVWGRQLLKQGFVSAL
>A0A6J3QBU9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tursiops truncatus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFSVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPLKKPASVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVLYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C7UNC5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MEQQVSDEEESQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKGAALWATLCCLPAPSLFCIGHILLVIHRNKAS
QTIKVSIDDTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDF
HWVRQCLKNGEEIHLVLESAPNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVF
TISLWDCHRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLW
NTWLEFNIRIRDLPKGARLSLQVSCGKAQTQISKGGSGSHDCNKTKSRLLYYVNLLLVDH
RSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYPVALPK
SREGKEAGGEGREAEGGERGQREMPNHLRKQFEAIVETDPLHPLSQEDKELLWHFREECM
RHPRAYPKLLGSVRWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSM
AVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEI
AQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQV
VFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTTL
SSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVK
DATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLG
VGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSS
PHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEE
AQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A8B9NUP9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Apteryx owenii|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHTY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEERIQSLVGVSWMDWLKHTYPPEQEPVIQE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRTTTSVWDICNPFKIILLKGYKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEILEFEINVCDLPRMARLCFAVYAVMDKVKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELILHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLPPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCKYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQCCEDAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K7WZI0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mohoua ochrocephala|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTADFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKIAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWNQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQGI
>A0A8B9VGE7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas zonorhyncha|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMLVAEVA
ACTRGGKLFVYGWERSTDPSSFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYTL
QVNGKYEYLYGNYPLYQFQVSLLSSFISESVPLCPLPNYGSLWSLEQPFYIELVQGSKVN
ADERMKLVVQAGLFHGNEMLCKMVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFAL
YAVIEKAKKARSTKKKSKKAVSKDCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGE
LLNPMGTVQCNPNTESAASLVICFPNVASHPVYYPSFDKPFGLRLSPLYALFCDSHEQKL
QLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQ
TWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDNELFQYLLQLVQVLKYESYLDCEL
TKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHIKVLMKQGEAL
NKMKALNDFVKVSSQKATKPQTKEMMHVCMKQETYLEALSHLQSPLNPSIILAEVCVDQC
TFMDSKMKPLWIVFNNEETSGGGVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRM
TPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQ
AIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERV
PFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELS
CSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A670YGG4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pseudonaja textilis|TrEMBL
AYWGPGVIPTLCMIGSTVKWYISLRLLLSSFQVVWHQAQYEPFFQMLSAPDSYVFTCINQ
AAELQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLLNSQISLLIGKGLHEFDSLADPE
VNDFRVQMQDYCEQKAAQRQQLSWKDWMEYSFPVQLEPALSGLGRRPSLPMPGKTIFVNV
KFQSGGSFTFQISLKEFPITLMSYAVKKQATIFRHQRVSPADEYTLQVNGKYEYIYGEYP
LYQFQYIRECLHRRFVPHLIMVHRSSLLTLREEQSNGLGHPPKTNWIGSSLGWINLLPSP
IYLLFFQLVVQAGLYHGHEMLCKMMTSTEANVCSEPTWDQTLKFDIHVCDLPRMARLCLV
LYSVVEKAKKARSTKKKSKKADCPLAWVNVMLFDYQDQLKAGECVLPMWSAFPDEKGELL
NPTGTIQTNPNAESAATLFIRFPGISLYPIYYPSMRQVRLLKEILERRSCIELYEHEKDL
VWKMRYQIRDQYPGALAKLLMVTKWNKHEDVAQMIFLLQSWPELPVLNALELLDFNFPDP
HVSRFTVNSLKKLTDAELFQYLLQLVQVLKYQSYLDCELTKFLLGRALSNRKIGHFLFWH
LRSEMHFPSLALRFGLILEAYCRGNADHIKALMKQSEALNKLKALNDLIKVSAQKNTKPQ
TKEFMHTCMRQETYLEALSHLQSPLDPRIFLARVSVELCTVMDSKMKPLWIMFNNGEAGG
PNTGLIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKMGLIEVVMNS
DTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGI
GDRHSDNIMVRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSE
KFERFRDYCERAYMILRGHGLLFLHLFSLMKAAGLPELSCSKDIQYLKDSLALGKTDEEA
RKQFHLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A670YGG9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pseudonaja textilis|TrEMBL
MPPGMYCPSEFWSKESNYTIHVDFLLPTGIYLPLPVSCHASLAAIKKVVWHQAQYEPFFQ
MLSAPDSYVFTCINQAAELQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLLNSQISLL
IGKGLHEFDSLADPEVNDFRVQMQDYCEQKAAQRQQLSWKDWMEYSFPVQLEPALSGLGR
RPSLPMPGKTIFVNVKFQSGGESFTFQISLKEFPITLMSYAVKKQATIFRHQRVSPADEY
TLQVNGKYEYIYGEYPLYQFQYIRECLHRRFVPHLIMVHRSSLLTLREEQSNGLGHPPKT
ALKLSPGPKQKLTCVSLWSLDQPYYIELLHCSKVNADEGMKLVVQAGLYHGHEMLCKMMT
STEANVCSEPTWDQTLKFDIHVCDLPRMARLCLVLYSVVEKAKKARSTKKKSKKADCPLA
WVNVMLFDYQDQLKAGECVLPMWSAFPDEKGELLNPTGTIQTNPNAESAATLFIRFPGIS
LYPIYYPSMRQVRLMIFLLQSWPELPVLNALELLDFNFPDPHVSRFTVNSLKKLTDAELF
QYLLQLVQVLKYQSYLDCELTKFLLGRALSNRKIGHFLFWHLRSEMHFPSLALRFGLILE
AYCRGNADHIKALMKQSEALNKLKALNDLIKVSAQKNTKPQTKEFMHTCMRQETYLEALS
HLQSPLDPRIFLARVSVELCTVMDSKMKPLWIMFNNGEAGGPNTGLIFKNGDDLRQDMLT
LQMIQLMDILWKQEGLDLRMTPYGCLSTGDKMGLIEVVMNSDTIANIQLNKSNMAATAAF
NKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRENGQLFHI
DFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRDYCERAYMILRGH
GLLFLHLFSLMKAAGLPELSCSKDIQYLKVRKKRVEWVHRQNLFRRTQIVESKRLTL
>A0A673CVP8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
MPPRPSSGELWGIHLMILVDWLPNGMILTLECLREATLITIKHELFKEARKYPLHHLLQE
ETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMP
VQDFRRNILNVCDSVELRDASGPHSRALYVYPPNVESTQELPKHIYSKLDKGQIIVVIWV
IVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQGKYILKVCG
CDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTDNFVMPSYSRRISTATS
YMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQMCDNVNTQRW
LTYDMYIPDIPRAARLCLSICSVKGRKGAKEHGVISICLTTLHSGGQQMALNLWPVPHGL
EDLLNPIGVTGSNPNKETPCLELEFDHFSSPVKYPDMNAVEDHANWTISRELGFNYNLSG
QSNRVARDHALTDSDTEQLRQLSNRDPLSEITEQEKDFLWRHRHYCMNIPEILPKILLAV
KWNSRDEVAQMYCLLKEWPSIRPEQAMELLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYL
IQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYC
RACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMRFLVDQMKRPDYMDALQNFT
SPLNPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDML
TLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQF
NSNTLHQWLKDKNKGEMYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHI
DFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECAKTKEFERFQEMCYKAYLAIR
QHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKTEQEALDYFMKQMNDAHHGGWT
TKMDWIFHTIRQHALN
>A0A672ZWN9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
MPPGKYGMQEEWEKEGDQGIMMDFLLPTGIFLKFLVSRNDTIKSIKKMVWKNARSEALFA
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRMFCEEKALDRQRLPWQQWMEYSFPCDLEPCCSPPEC
GNAKSKNTKKLFINVKFEASDESFMLQQDPQDLPVALIRSALKKKATVFRSVRQEPEDYT
LQVNGRWDFIYGSHPLCQYKSRSLSRPPPLPLKKNTSSLWSINEPFYIQLLQGNRVNADE
GMKLVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAV
IEKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMG
TVEKNPNVDSAAGLLIRFPNIRQHPLYYPPLEKVLDPKHFCTGITSSRKNDKTILVFFNF
LFILMPGVTKGTFVWTNIMITTKIAHKSLISEVYMKLKEIMDNKNYTEFFEDEKELLWKL
RSVVRDHYPESLSKLLLITKWNKREDVVQMVGLLRNWPELPAIHALELLDYSFPDPAVRS
FTIRCLRKLSDGELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSE
IHVASVSCVFGLILEAYCRGNIHHIKLLTNRYLPTLSKSGSQKMTAEDLKLCIRQESYVE
ALSDLLADKCRFMDSKMKPLWMMYRNPFVQGDMVGIIFKNGDDLRQDMLTLQMIQLMENL
WKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDEKLEKAI
EEFTLSCAGYCVATYILGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPF
ILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSF
KDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A8B9VEW6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas zonorhyncha|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GLLHTPTKNIFVNVKFQSGGESFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYT
LQVNGKYEYLYGNYPLYQFQMSPKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADER
MKLVVQAGLFHGNEMLCKMVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVI
EKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGT
VQCNPNTESAASLVICFPNVASHPVYYPSFEQVGGMDVKSCISILPTTSYFHQPGSWVLW
GFSELSKPFGLRLSPLYALFCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQ
YPQALAKLLIITKWNKHEDVAQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDNE
LFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLI
LEAYCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCMKQETYLEA
LSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIFKNGDDLRQDM
LTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATA
AFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLF
HIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILR
RHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWK
TKVNWLAHNVSKDNRQ
>A0A672ZXH4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
MPPGKYGMQEEWEKEGDQGIMMDFLLPTGIFLKFLVSRNDTIKSIKKMVWKNARSEALFA
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRMFCEEKALDRQRLPWQQWMEYSFPCDLEPCCSPPEC
GNAKSKNTKKLFINVKFEASDESFMLQQDPQDLPVALIRSALKKKATVFRSVRQEPEDYT
LQVNGRWDFIYGSHPLCQYKYIFFCLRNGQNPHLTMVHHSTISKYQEEQGQMCNQVFKSR
SLSRPPPLPLKKQNTSSLWSINEPFYIQLLQGNRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RQHPLYYPPLEKVLDPKHFCTGITSVICQVKNLVLKEIMDNKNYTEFFEDEKELLWKLRS
VVRDHYPESLSKLLLITKWNKREDVVQMVGLLRNWPELPAIHALELLDYSFPDPAVRSFT
IRCLRKLSDGELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIH
VASVSCVFGLILEAYCRGNIHHIKLLTNRYLPTLSKSGSQKMTAEDLKLCIRQESYVEAL
SDLLADKCRFMDSKMKPLWMMYRNPFVQGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWK
KEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNRWINSKRKTSIEEFTLSCA
GYCVATYILGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVH
VIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKD
SLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A673CRN2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
MPPRPSSGELWGIHLMILVDWLPNGMILTLECLREATLITIKHELFKEARKYPLHHLLQE
ETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMP
VQDFRRNILNVCDSVELRDASGPHSRALYVYPPNVESTQELPKHIYSKLDKGQIIVVIWV
IVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQGKYILKVCG
CDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTDNFVMPSYSRRISTATS
YMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQMCDNVNTQRW
LTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLMALNLWPVPHGLEDLLNPIGVTGS
NPNKETPCLELEFDHFSSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALT
DSDTEQLRQLSNRDPLSEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMY
CLLKEWPSIRPEQAMELLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQY
LDNPLARFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSR
QVEAMEKLINLTDILKQEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNL
RLDECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIW
QNQGLDLRMLPYGCLSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDK
NKGEMYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKK
FGYKRERVPFVLTQDFLIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSM
MLGSGMPELQSFDDIAYIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQ
HALN
>A0A3Q1INK9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MDRKQIQVSDEEPVVLREEIRRRRRKKAITSSSSISMDQITVEFVLPTATWGSNPDSLQL
EVAGNWTVEQVKAQVWLKAVTSNLCPEFYQRFSPDHCILLYQKKGNLCEIYDKHQVFQTL
DCIRYWRALKKDVGKIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRRIELCDRDPKLYSMDPWVTRKPLPEHLLSKVSNGHILVVIHMSTASHTIKVSIDD
TPVLASFFNKTANKRVLLGIPDNVCETDYVLRVCGRYEYLYGDKPLQNFNWIRQCLKNGE
EIHLVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKF
RVKVLGIDIPTLPKVPEFVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKIK
DLPKGARLSLQVNSNINLKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEESSS
SINADKLTSATNPDKESSMAIAILLDKYCYPVVLPKSRDVGRDVGAVGEESEGGERGQRE
MPNHLKKQFEAIVTTDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVKWGKQEDVLA
THRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQA
VKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGE
AMLQDFRKQVEMTEALQKVTREIKTMSADKYDVTAQVVFQLRQKLEILQSSGLPDNFRVP
YDPGLRAGALMIEQCKVMASKKKPLWLQFKKADPTTLSKDPIGIIFKDGDDLRQDMLILQ
ILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFKDEI
LYQWLRDKCVSEEKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFG
HILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTNL
LIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQINW
FVHLVLGIKQGVEKRST
>A0A8C6D2R6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Moschus moschiferus|TrEMBL
MCFYFMMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISCIKQMLW
KQVTNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPEL
EPSVPENLEDKLYGGKLIVAVHFENCQDVFSFQVFPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHSLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMVAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEEAVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEPLEFDINTCDLPRMTRLCFAVYAVLDKVKTKKSTKTM
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPHALPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A672R6T3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPGVYGMQDVWEREGWQQVNMEFLLPTGIYLNFTVTSSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGLCHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWDQWMEYNFPCDLEPCSVVA
QSGKSCSDKKIFVNVKFEGSETDIFSQGPQDLPMFLKQNALRKKSTVFRSAKQEKPEDYA
LQINGRWEFIYGKYPLCQFKVSLKITPSSRLHSYIFFKFHIKVSHFQTPGSLQSLSFSQL
VVQAGLFHGSELLCKVVTSNEVSVCSEPVWDQKLVFDISASDLPRMSRLCIALYGVIEKT
KKRPTKKKNKSSDCPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPDLLNPMGTVEKNPNID
STAGLLIRFPNIRPHPLYYPPIEKTLLLRNVFFQHLKLREIVDNKNYTEFFEDEKELLWK
LREVVRQRYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHAR
SFTIRCLRKLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRS
EMHVSSVSLRFGLILEAFCRGSIFHLKNLMKQNEALNKMKALNDFVKSGSQKATRIQTTE
DMKVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDTLGII
FKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANI
QRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFR
ECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLMDSLALGKSEEEALKNFKV
KFNEALRESWKTKVNWMMHTFAKDNR
>A0A672R7N4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPGVYGMQDVWEREGWQQVNMEFLLPTGIYLNFTVTSSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWDQWMEYNFPCDLEPCSVVAQS
GKSCSDKKIFVNVKFEGSEETFVLQQGPQDLPMFLKQNALRKKSTVFRSAKQEKPEDYAL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDISASDLPRMSRLCIALYGVIEKTKKRPTKKKNKSSDCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGLNGEKTVATKEEMVGLLRKWPELPAIHALELLDYSFPDPHARSFT
IRCLRKLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMH
VSSVSLRFGLILEAFCRGSIFHLKNLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMK
VCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDTLGIIFKN
GDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRN
NSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECC
EQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLMVRIAQTGIIYYP
>A0A226PU28|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Colinus virginianus|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDIRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
NFQDKLYSGNLVVAIHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEIDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEVAIN
RKSSNLPLPLPPKKTRATTNSVGSVVGLSISFLISFMQVHVRAGIFHGTELLCKTVVSTE
ISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKSMNPSKYQTIRKAG
KVHYPVAWVNTMVFDYKGQLKNGEFVLHSWSSFPDELEEMLNPMGTVQTNPYTENATALH
IRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEIMERDPLSQLC
ENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPREALELLD
FNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIG
QMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAM
KQSKAKGKDAMHTCLKQNAYKEALSDLQSPLNPSVILSELHVEKCKYMDSKMKPLWIVYN
NKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLATGDHSGLI
EAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSCAGYCVA
TYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQG
KTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALG
KSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A834QZ94|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Marmota monax|TrEMBL
MLWHEAQNEPLFHMLSDPEAYVFTCVNQTAEQQELEDEQQRLCDVRPFLPMLRLVTRQGD
RMEKLINSQISLLIGKGLHEFDCLQDPEVNDFRTKMRQFSEEEAARRQQLGWEAWLQYSF
PLQLEPSTRSWGDSNTSQISNPDLLVNVKFEGSRESFIIQVSTKDVPLVLMAGALQKKAK
VYQHLTMEKPEDYVLQVNGWHEYLYGSYLLCQFKFNFTLSSQYICSCLHSGLTPHLTMVH
SSSILAMRDEQSKPAPQVQKPHTKLPPIPMKKPSSVSLWSLGQPFCIELIQGSKINADEQ
MKLVVQAGLFHGNEMLCKTMSSLEVSVCSEPMWKQHLEFDINICDLPRMAQLCFALYAVM
EKAKKARSSKKKSKKVDCPIAWANLMLFDYKDQLKTGELCLYMWPSVPDEKGDLLNPMGT
VHSNPNTESAVTLVIYLPKVSPHPVYYPALEKKLQLQGILDQRGSGELYEHEKDLVWKMR
HEVQEHFPEALAHLLLVTKWNKHEDVAQMLYLLCSWPELPVLNALELLDFSFPDCHVGSF
AIRSLQKLTDDELFQCLLQLVQVLKYKSYLDCELTQFLLDRALAN
>A0A672I4E4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salarias fasciatus|TrEMBL
MPPGKYGMQEEWEKEGEVVMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFSGL
GDPDAYVFTCINQTAEREELEEESRRVSDVRPFMCVLRLVAREGDRVEKLTNAQISLLIG
KGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERQSLPWHQWMEYSFPCDLEPCCSPPGSKT
KNTKKIFVNVKFEASDESFMLQQDPQDLPMALMRSALKKKATVFRSVRQEPEDYTLQVNG
RWEFIYGRHPLCQFKYIFSCLRNCQNPHLTMVHHSTISKYQEEQGRMCSQVYKTRSLSRP
PPLPLKKNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSSEVT
VCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKRADCPIAWVNTM
VFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRYPNIRPHPLY
YPPLEKIADVERNVDPVFPTKEENVRLKEIMDNKNYTEFFEDEKELLWKLRAEVRDRFPE
SLSKLLLITKWNKREDVVQVSTKSVYLLKKWPDLPAIHALELLDYSFPDPAVRSFTIRCL
RKLSDGELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNKRIGHFLFWHLRSEIHVASV
GLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDIVKSGSQKMTAEDLKLCIRQESY
LEALSDLLSPLNPSVVLAEICADKCRFMDSKMKPLWLMYRNPLAQGDMVGIIFKNGDDLR
QDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNNSNSA
ATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYK
ILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSDEEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDNRP
>A0A672GY23|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salarias fasciatus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQLDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRIKMFRLSEERMQRVQMMTCTEWLQACFSPQLEPP
AATAVTDGVNDRAADLKVIIHFDQSQDSASLKVPSCYTPAELMEQALRKWVTTHGPEEEA
WGGQHVLRVSHCLEFLCGDHPLIQYKYIRSCLQAKEPPHLTLVHTNTVKAMFDKEMTAIG
AVVSRRSSNPPLPLPPKRRTCVWDVSSPFKIVLVKGSKVNAEETAKVQVRAGLFHGTELL
CKPAVSSESSGQRASSEHTWRDNTLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNS
HINKYQTIRKAGKVHYPIAWVNTMVFDFKGQLKTGDITLHCWSSFPDELEEMLNPIGTIQ
TNPYTENATALHIHFPEYSSHPIIFPPFDKILEKAAEIVGASDCVSGARGGKKFYIELKE
IMERDPLSQLCENEKDLIWTLRHDCWENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPK
LSPRDALELLDFNYPDQYVREYAVRCLRDMSKHAASRVFLLIRTLGDEELSQYLLQLVQV
LRYEPYYDCALTHFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPH
IEVLKKQVEALSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLH
SPLNPNVQLSGINVERCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQI
LRLMDLLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKD
ALLNWLKERNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFG
HILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLVLRKNGNL
FITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNW
MAHNVAKDNRS
>A0A3Q3S6N7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDSVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYSQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKVGMPATD
PQLQWNEWLTYDMYISDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVA
NKMALNLWPVPHGLEDLLNPIGITGSNPNKETPCLELEFDHFSSPVKYPDMNAIEDHANW
TISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPLSEITEQEKDFLWRHRHYC
MNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAMELLDCNYPDPMVRHFAVRC
LEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSEMHNK
TVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMRFLVDQ
MKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMSELLFQNNE
IIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRSSHTIM
QIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDMAVDLFTRSCAGYCVATFILGIGDRHN
SNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECTKTKEFI
ASVCHSLFPGFCRRPWITL
>A0A673UJC4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Suricata suricatta|TrEMBL
MELDSYEQPVVLREENRRRRRRMKPRSTTASLSSMELIPIEFVLPTSQRNSKTPETALLH
VACHGNVEQMKAQVWLRALETSVAADFYRRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQIHLVQRQTPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCSKVPVLPGKASAETPSSESRGKTQLLYYVNLLLIDHRFLLRYGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLQDFTDQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIEKEENVPRLVTATLHL
>A0A7K6T1K9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Caloenas nicobarica|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKALGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLMPHLTMVHSSTIIAMRDEQTNCIASPPKMP
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWRQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2K8FKV1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSAQTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A6P8SDT3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MPPRPSSGELWGIHLMPPRIQVECLLPNGMMVCLECLREATLVTIKHELFKEARKYPLHH
LLQDESSYIFVSVTQEAELEEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDMVKDPEVQEFRRNVLNVCKEAVDLRDANGPQSRALYVYPPNVESSPELPKH
IYAKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPVD
NFTMPSYSRRISTATPYMNGEASVKPLWTINSSLRIKILCATYVNVNIRDIDKIYVRTGI
CHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGMEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMMVIEEHANWTISRELGFNYSHAGLSNRTARDCELRESDKEQLRAVCTRDPL
SEITEQEKDFLWSNRHYCLYTPEILPKLLLAVKWNSRDEVAQMYCLLKDWPPIKPEQAME
LLDCNYPDPMVRAFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFSSPLNPAHQLGTLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGIKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTRDFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8D0U9K7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPGVDCPMEFWTKEENQSVDVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSDPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNRHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRYSEMHVPS
VALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCM
RQETYLEALSHLQSPLDPSPAPDGCAPGSVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGI
IFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIAN
IQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERF
RGYCERAYAILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFR
VKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A341BSN2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neophocaena asiaeorientalis asiaeorientalis|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
AKPPPIPLKKPASVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEELQLREILERRGSGELYEHEKDLVWKMRHEIQEH
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMQLCLRQ
ETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKLPVEKAKPPAFGAKTSGLKLAS
YFEDGAGRGPPWLGSERRALPGEVLGRCPPGSLGAVLLGGSVTCPERVEVQGDGAPC
>A0A7L1XLW0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Thinocorus orbignyianus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKKPNYGSLWSLEQPFHIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGDQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P5BVS7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos indicus|TrEMBL
MCFYFMMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISCIKQMLW
KQVTNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPEL
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHSLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMVAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEPLEFDINTCDLPRMTRLCFAVYAVLDKVKTKKSTKTM
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPHALPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKTEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8B9LYQ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Accipiter nisus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAL
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K6FW10|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Daphoenositta chrysoptera|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSTELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIMGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMQSIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C0RPI8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MEPQGREPRVVLREDHRRRRRRMKARGPAAGLPSMELIPIEFVLPTSQRSSKAPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYQRLGPDHFVLLYQKKGQWYEIYDRYQVVQTLD
CLRYWQLLHRSPGQIHVVQRRAPSAATLAFQRQLTALIGYDVTDLSNVHDNELEFTRRRL
VTPRMLEVAGRDPELYAMHPWVTSKPLPDYLRKRIPNNCVFIVIHRGTTSQTVKVSADDT
PGAILRSFFAKMAKKKALMGIPEGQSERDFVLRVCGRDEYLVGDTPLQNFQWVRQCLKNG
EEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRR
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFSIKI
KDLPRGALLNLQVYCSKAPTLSAKASADAPGAGSEARGKAQLLYYVNLLLIDHRFLLRRG
EYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDP
EGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKW
GQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLH
YLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLE
AYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLN
LPESFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDL
RQDMLILQILRIMESIWETESLDLYLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGN
TGAFKDEVLNHWLKEKCAIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETG
NLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYL
ALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDK
GWTVQFNWFLHLVLGIKQGEKHSA
>A0A8C0Z6U5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNDFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPNDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKMRIISVHVRAGLFHGTELLCKTIVSSEISGKNDHIWNEPLE
FDINTCDLPRMARLCFAVYAVLDKVKTKKSTKNINPCKYQTIRKSGKVHYPVAWVNTMVF
DFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIKFPENKKQPYYYP
PFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQDCR
ENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGC
LRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVHIPA
VSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNKAKGKEAMHTCL
KQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKN
GDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLN
SSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIM
VKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCC
EDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFD
EALRESWTTKVNWMAHTVRKDYRS
>A0A2I2YNX7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gorilla gorilla gorilla|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQSGWSRSPDLMIHLPQPPKVLGLQHVWENNNPFQ
IVLVKGNKLNTEETVKVHVRAGLFHGTELLCKTIVSSEVSGKNDHIWNEPLEFDINICDL
PRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRT
GDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHVKFPENKKQPYYYPPFDKIIEK
AAEIASSDSANVSSRGGKKFLPVLKEILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLP
KLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEE
LSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVI
LEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREA
LSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDM
LTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAA
AFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLF
HIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILR
RHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWT
TKVNWMAHTVRKDYRS
>A0A8C4NX90|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MPPGKYGMQEEWEKEGDQGILMDFLLPTGIFLKFPVSRNDTIKSIKKVCPHTQSEALFSG
LGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRVEKLTNTQISLLI
GKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPMSG
SMKSKSTKKIFINVKFEACDESFMLQQDPQDFPVALMRSALKKKATVFRSVRQEPEDYTL
QVNGRWEFIYGKHPLCQFKYIFSCLRNGQNPHLTMVDHTTISKYQEEQGRMCSQVYKSRS
LSRPPPLPLKKNTSSLWSINEPFYINLVQGSRVNADEGMKLVVQAGLFHGSELLCKVVTS
PEVAVSSEPLWDQNLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFHNIRP
HPLYYPPLDKISDVEKNGDAGIPTKEEMVSLLRKWPDLPAIHALELLDYSFPDPAVRSFT
IRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLSERLQ
PFGKHSPHQALNQTGNLTHLYTLTSSSEMCVFNEALGKMKALSDFVKSGSQKMTVDDLKL
CIRQESYLEALSDLLSPLNPSIVLSEICADKCRFMDSKMKPLWLLYKNPQAQGDMVGIIF
KNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYACLSTGNKMGLIEVVKNSDTIANIQ
RNSSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDN
IMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRE
YCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQHSANVYISLACLWYITTKRRHP
KTMM
>A0A7K7SEZ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sapayoa aenigma|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGAIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGP
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMREEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWTLEKPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKREGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A834EB85|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phyllostomus discolor|TrEMBL
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYCFPLQLEPSARTWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDMPLALMTCALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHRGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGEYCLYMWPSVPDEKGELLNPTGTVCSNPNTESAAALIICLPEVAP
YPVYYPALDKILELGRHGEHGRFTEEELQLREILERRGSGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLCLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSIHHMRVLMKQGEALSKLKALNDFVKVSSQKTPKPQAKELLHVCMRQ
ETYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVMYCNEEAGSNGSVGIMFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A834AG55|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phyllostomus discolor|TrEMBL
MPPGVDCPMEFWTSEENQNVAVDFLLPTGVYLNFSVSRNANLSTIKKALWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYCFPLQLEPSARTWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDMPLALMTCALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHRGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGEYCLYMWPSVPDEKGELLNPTGTVCSNPNTESAAALIICLPEVAP
YPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLCLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSIHHMRVLMKQGEALSKLKALNDFVKVSSQKTPKPQAKELLHVCMR
QETYLEALSHLQSPLDPSILLAEVWPGVGVPADRSLPGSVEQCTFMDSKMKPLWVMYCNE
EAGSNGSVGIMFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIE
VVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVAT
YVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGK
TNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGK
TEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A674D4L5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MEQQVSDEEPQPVVLREEIRRRRRKMKAFTSTFSVAMDQIAIEFILPTTTKSSRSPDTLL
LEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSSDHCILLYQKKGNWCEIYDKHQVFQT
LDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRKNELSDRDPKLYSMDPWITSKHLPEYLFTKVTNSHILLVIHRNKASQTIKVSID
DTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCLK
NGEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDCH
RKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFNI
RIRDLPKGARLSLQVSCGKAQTQISKGGSGSHDGSKTKSRLLYYVNLLLVDHRSLLRQGE
FILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAIAILLDKYCYPVALPKSREGERGQ
REMPNHLRKQFEAIVETDPLHPLSQEDKELLWHFREECMRHPRAYPKLLGSVLWGRQEAV
LATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLETLGDDDVLRYLLQLV
QAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGC
GEDMLQDFRRQVEITEALQKVTREIKAMSAEKYDVSAQVVFQLRQKLENLQTSGLPESFR
VPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTTLSSDTIGVIFKDGDDLRQDMLI
LQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSVVGSTGAFKD
EILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLGVGDRHNDNIMITESGNLFHID
FGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVRAYLALRHHT
NLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEEAQRHLLDQIEICRDKGWTVQF
NWFLHLVLGIKQGGDKRSA
>A0A673ZFA8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPAMPDDLDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFCPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQACFSPQLEPGGG
ATPLTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRYIKACLQAKECPHLTLVQVSSVQAMFEKEISAIGAVVNRKSSNPPLPLPP
KRRGPSFKIVLIKGSKVNAEESAKVQVRAGLFHGTELLCKPVVSSESSGRSEHVWNRTLE
FDITVSDLPRMARLCFAVYAVMDKVKKQKSTKNAHINKYQTIRKAGKVHYPVAWVNTMVF
DYKGQLKTGDIILHSWSSFPDELEEMLNPIGTIQTNPYTENSTALHIHLPDYNPHPILFP
PFDKILEKAAEIAGSSDCSTMSRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCM
ENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVGC
LRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLNRAQCNRNIGHFLFWHLRSEMHMPA
VSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSKTKEAMLTKE
AMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMDSKMKPLWIVYNNKLLGGDTL
GIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSSADTI
ANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKAIEEFTLSCAGYCVATYVLGIGDR
HSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFG
SFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKVIGRFTWDSLALGKT
DDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A8C4IZL0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dromaius novaehollandiae|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHTY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIQE
SFQDKLYSGNLVVAIHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPTD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLIECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDICNPFKIILLKGYKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKVKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELILHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAXSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCKYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQCCEDAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>K9INT5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Desmodus rotundus|TrEMBL
MCFNSIMPPAMADILDIWAVDSQIPSDGPIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQIHNYPMFSLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWIDWLKQTYPPEH
EPSNLENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQISGRLEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNFPLPLPPKKTRIISHVWENNSPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NASKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSKRIQSRIGKGKRFIGQSLEETSDEELSQY
LLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVHIPAVSIQFGVILEAY
CRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDL
QSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQ
MLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNK
DALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDF
GHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGN
LFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEDEALKQFKQKFDEALRESWTTKVN
WMAHTVRKDYRS
>G1PD89|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myotis lucifugus|TrEMBL
TMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLH
QLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGF
AIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPK
HIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQL
KLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPM
DCFTMPSYSRRISTATPYMNGETSTKSLWGINSALRIKILCATYVNVNIRDIDKIYVRTG
IYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEH
CPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLEMEFDW
FSSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGPSNRLARDNELRENDKEQLRAICTRD
PLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQA
MELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKAL
TNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDI
LKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRP
LWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGC
LSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFT
RSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQ
DFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDD
IAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A099YPK7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tinamus guttatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWSINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYEMYITDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVI
>A0A8C9CFX0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phocoena sinus|TrEMBL
MPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKQTYPPEHEPSIPE
NLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDEVSPYDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAIEAAINR
NSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TVVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKAINPSKYQ
TIRKSGKVDYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALA
NRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLKTLNSLI
KLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYIEKCKYMDSKMKPL
WLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGD
HSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCA
GYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A663LSE5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Athene cunicularia|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCISSPPRMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLK
KLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVA
LRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHVCMKQ
ETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGD
DLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKS
NMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIR
ETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEK
AYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKVRYLTRYG
>A0A7L2B0F2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Heliornis fulica|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNSSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQVWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFRKITNNNIFIIIHRGTTSQKVKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTTLQSHDSPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSPLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFTKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQEVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3B4FZI6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pundamilia nyererei|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVMRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRSKMFRISEERMQQIQMMAFSEWVQACYSPQLEPA
AVTAITAGVNDAPVDLKVIIHFDQSQDSASLKVSLSCTPNELMEQALKKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKEAPHLTLVHTSTVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRRAPTQVQTCVWDVPKPFRIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSNESSGRSEHTWKDNTVEFEISVCDLPRMTRLCFAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHPIVFPPFDKILEKAAEMVSADCVSIGRGVKKFYMEL
KEIMERDPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVRCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTH
FLLERAQRNRQIGHFLFWHLRSEIHMPAVSVQFALLLEAYCRSNIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRIVPYGCLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSNGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7L1WKB1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Certhia brachydactyla|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVRFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKMLLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKTTKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMQSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q2CNI7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinodon variegatus|TrEMBL
MDRQQIQVSDEERQVAREESRNRRRRKKAITSSSSASMDQISVEFVLPTVARGGSSPDLL
LLEVAGNWTVEQVKAQVWMKAVSLNLCPDFYQRFSPDHCILLYQKKGTVCEIYDKHQVFQ
TLDCIRYWRALKKDVGRITLALRPQPSDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRRIELLDRDPRLYSMDPWVTRKPLPEHLLSKVNNGFILVVIHVSTSSQTIKVSI
DDTPSQVLASFFAKTANKRVLLGIPEDVSEEDFVLRVCGREEYLYGEKALQSFNWIRQSL
KSGEEIHLVMETPPDPELDLVQREDWAQVDDCTGVTGTHEQLTIAEKDHERVFTISMWDC
NRKFRVKVLGIDIPTLPKVPDFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFN
IKIKDLPKGARLNLQVICGKQPVPPSSKGSYHENTAGTGTLEAKTKNRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLP
KSRDVGRDCGGEEGDAGDRGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRHECM
RDPRAYPKLLGSVKWGKQEDVLATHRLLDRSHAWDTSGLDVGLAMQLLDCHYSDAQVRSM
AVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEI
AQSMHYQQRYAVLLEAYLRGCGENMLQDFRKQVEMTEALQKVTREMKAMSADKYDVTTQV
VFQLRQKLETLQSSGLPEGFRVPYDPGLRAGGLLIEQCKVMASKKKPLWLQFKRADTTTL
SKDPIGILFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVK
DATTIAKIQQSVVGSTGAFKDEILHQWLRDKCVSEEKFQQAVERFLYSCGGYCVATYVLG
IGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSS
PHFLKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDE
AQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A3Q2DX33|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinodon variegatus|TrEMBL
MDRQQIQVSDEERQVAREESRNRRRRKKAITSSSSASMDQISVEFVLPTVARGGSSPDLL
LLEVAGNWTVEQVKAQVWMKAVSLNLCPDFYQRFSPDHCILLYQKKGTVCEIYDKHQVFQ
TLDCIRYWRALKKDVGRITLALRPQPSDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRRIELLDRDPRLYSMDPWVTRKPLPEHLLSKVNNGFILVVIHVSTSSQTIKVSI
DDTPSQVLASFFAKTANKRVLLGIPEDVSEEDFVLRVCGREEYLYGEKALQSFNWIRQSL
KSGEEIHLVMETPPDPELDLVQREDWAQVDDCTGVTGTHEQLTIAEKDHERVFTISMWDC
NRKFRVKVLGIDIPTLPKVPDFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFN
IKIKDLPKGARLNLQVNPACLGYCFLTNSIFKKYTLLKTPIWSKTKNRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLP
KSRDVGRDCGGEEGDAGDRGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRHECM
RDPRAYPKLLGSVKWGKQEDVLATHRLLDRSHAWDTSGLDVGLAMQLLDCHYSDAQVRSM
AVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEI
AQSMHYQQRYAVLLEAYLRGCGENMLQDFRKQVEMTEALQKVTREMKAMSADKYDVTTQV
VFQLRQKLETLQSSGLPEGFRVPYDPGLRAGGLLIEQCKVMASKKKPLWLQFKRADTTTL
SKDPIGILFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVK
DATTIAKIQQSVVGSTGAFKDEILHQWLRDKCVSEEKFQQAVERFLYSCGGYCVATYVLG
IGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSS
PHFLKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDE
AQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A6J2HJ66|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pipra filicauda|TrEMBL
MAQTGVMEFDGKAADEAAGTLKQYEANDHTRQWQQFPWVLRSISSGMELGDHEQPVVMRE
ENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMMLLEIAGNCTVEQMKAQI
WMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLDCILYWKVLQKKVGK
IYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRLVTPRMIEVACRDPK
LYAMHPWTTSKPLPEYLFKKIINNNIFIIIHRGTTSQKIKVSIDDTPDMILHSFFTKMAK
KKSLMDIPEDHSELDFVLRVCGRDEYIIGETPVKDFHWIRQCLKNGEEIHLVLDDPPDPN
EDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRKFRVKIIGIDIPILP
RNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKIKDLPKGALLNLQIY
CGKAQGPSTKTNLQSHESSNSDTKCKTQLLYYVNLLLIDHRFLLRSGEYVLHMWKIPGKG
EEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRIASDPQGDRTRAEMPNQL
RKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQEIVAKTYQLL
AKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVLHYLLQLVQAVKFEP
YHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLHD
FMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSSKLPESFRVPYDPGL
RAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIM
ESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEILNQWL
KERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGN
YKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDICVKAYLALRHHTNLLIILF
SMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDKGWTVQFNWFLHLV
LGIKQGVEKHSA
>A0A384D4U5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus maritimus|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRHSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLLDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIQI
KDLPRGALLNLQIYCSKAPAPTGKGSADTPGSEGKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLEAY
LRGCGTAMLHDFSQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQMRKLSSREVK
>A0A8J0UR14|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus laevis|TrEMBL
MELDNYEQPVVLRDENQRRRRRMRPHSATTSVFSMDLIPIEFIMPTINRCSKVQETMLLE
VAGNCSVEQMKAQVWMHAIEKSHNSDFYQRLTPDQFLLQYQKKGQWYEIYDKHQVIQTLD
CIMYWKVLQKTVGKIHIVQKEKTPEEMIEYQKTLNYLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIELSRRDARLYSMDPWVTSKPLPEYLCQRITSNSIFIIIHKGMTSHTIRVSIDDT
PDVILHSFFTKMAKKKSLLEISEENSELDFVLRVCGRDEYIIGNAPIKDFHWIRQCIKNG
QEIHLVLEKPPNALKDDVQKEEWPLVDDCTGVTGYHEQLTIEGKDHEKIFTISLWDCNRK
FRVKIIGIDIPVLPKNTEIIVFVEANIQHGQQVLSQRRTTCKPFTEEVLWNSWLEFDLKI
KDLPKGALLNLQIFCGKAPNVSIKSNALSPESAASDSKFKNQLLYYVNLLLIDHRFLLRQ
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKETSMAISISLDKYCHPVALPKHKLVSD
PELERPRTEMPNQLRKQLEEIIATDPLHPLTPEDKELLWHFRSEIIKHPEAYPKLLSSVK
WGQQEMVAKTYQLLSKREAWDDCILDVGLTIQLLDCNFSDENVRAMAVQKLESLQDDDVL
HYLLQLVQAVKFEPYHDSALSRFLVKRALQSKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLDDFTKQVQVTEILHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQNA
KHPDKLPDSFRVPYDPGLRAGSLVVEKCKVMASKKKPLWLEFKCSDTTALSNETIGIIFK
HGDDLRQDMLILQILRIMGSIWEAESLDLYLLPYGCISTGNKIGMIEIVKDATTIAQIQQ
STVGNTGAFKDEVLSQWLKEKCPIEEKFSAAVERFVYSCAGYCVATFVLGIGDRHNDNIM
VTESGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSQYFNTFQDVC
VKAYLALRHHTNLMIILFSMMLMTGMPQLTSKEDIEYIRDSLTVGKNDESAKKHFLDQIE
VCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3Q2P418|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fundulus heteroclitus|TrEMBL
MDRQQFQVSDEERDVAREESRRRRRKKAITSSSSASMDQVNVEFVLPTAARGGSGPDSLL
LEVPGNWTVEQVKAQVWMKAVSLSLCPDFYQRFSPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLAPRPQQSEESQQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDSKLYSMDPWVTWKPVPEHLLSKVNNGYILVVIHVSTSSQTIKVSIE
DTPSQVLGNFFAKTANKRVLLGIPENMSEEDFVLRVCGREEYLYGERALQSFNWIRQSLK
SGEEIHLVLETPPDPELDHVQREDWAQVDDCTGVTGTHEQLTIAEKDHERVFTISMWDCN
RKFRVKVLGIDIPTLPKLPEFTVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIRDLPKGARLNLQVICGKQPQTANSKGGSYHENTAVTYSLEAKTKNRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLP
KSREVGRDCVVGSEEGDAGERGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRHE
CMRDPRAYPKLLGSVRWGKQEDVLATHRLLERSYAWDTSGLDVGLAMQLLDCHYSDAQVR
SMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSMHYQQRYAVLLEAYLRGCGENMLQDFRKQVEMTEALQKVTREMKAMSADKYDVTA
QVVFQLRQKLETLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPT
TLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEI
VKDANTIANIQQSVVGSTGAFKDEILHQWLRDKCVSEEKFQLAVEKFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKK
ISPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSE
DEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A4U5UL65|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Collichthys lucidus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTEELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYTLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A093ICN1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fulmarus glacialis|TrEMBL
MELGDYEQPVIMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEK
>A0A674GBJ4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGV
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGRTPHLTMVHSSAIIAMRDEQTNGITSPPKAA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQNPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFIL
TYDFVHVIQQGKTNNNEKFERGYCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQ
YLKDSLALGKTDEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A851TJ13|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothocercus nigrocapillus|TrEMBL
MPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWQHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRIKMRQFCEERAAKRQQLSWAAWMEYNFPLQLEPLAKGFGT
GPLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIANPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSIAS
HPVYYPSFEQLLELGRNGEQPRTALEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
VRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDGELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVEQCTFMDSKMKPLWIVFNNEETGGSGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGESLEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALAKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8J4TXT5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Clarias magur|TrEMBL
VPWFGCGVLSAMPPAMTDQLDVWADPVLDGNSQVAVDFLLPSGIYIQMDVPRESTIQQIK
QMLWKQAQVYPLFSLLGEMDGHIFECVNQAAVHEELEDESRRLCDVRPFLPVLRLITRNC
GRAERLLDSKIGVLIGKGLHELDALQDQEVKDFRSKMQRISEEKMQSVHMMSWVEWLQSC
FSPQLDVGPVDALCDRNEGFIKITMHYNQSQDTTSLKVPLSCTVPELMNQALRKWLTTHG
LGEDEDCVGNYVLRVSDKLEFLFGDHPLVSYRYIRSCILSQENPHLTLVHCDMVKTMFEH
EISSIGAVLARKSSNPPLPLPPKRRGPSTLHMSIWDVQSFFKITLVKGIKVNAEETAKVQ
VRAGLFHGTELLCKPAVSNESSGRSEHIWNKTLEFDISACDLPRMARLCFAIYAVMDKVK
KQKSTKNMQMNKYQTIRKAGKVHYPIAWVNMMVFDYRGQLKTGDIILHTWSSFPDELEEM
LNPIGTVQTNPYTENATALHIRLPEFSSNPPSFPPFDKILEKAADIAGSSDSMSMGRGGK
KFYTELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWNKHEDMAQLQ
ALLQIWPKINPRDALELLDFNYPDQYVREYAVGCLQDMSDEELLQYLLQLVQVLRYEPYY
DCALTQFLLQRAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQ
VEALSKLKTVNELIKLGTIKAKNKTKEAQLRDAMMKCLRQTGFIEILSDLHSPLNPQILL
ADVNVEKCRYMDSKMKPLWIVYHNKLLVGDTLGIIFKNGDDLRQDMLTLQILRLMDMLWK
EANLDLRIVPYGCLATGDRTGLIEVVSSADTIANIQKNSSNMAAAAAFNKDALLSWLKDK
NPGEALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSK
FGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEDAYLILRRNGNLFITLFALML
TSGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAHPS
>A0A8C1X6N9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
LVLSAMPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKE
AQTYPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERI
LDSKIGVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLE
TESVENLIDKHEGVIKITMHYDQSQVCSVILALKKWQTTHGPEEDIGTRSDYVLRVSCRL
EFLLEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAIFEKEICTIGSVLARKASNPPLP
LPPKKRTPTVRTLSVFPALQLIKGALSFVPLAVRAGLFHGTELLCKTAVSSESSSRSEHV
WNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHYPIAW
VNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYST
QPVVFPAFDKILEKAAEIAGASDSMTIGRGGKKFYIELKEIMERDPLSQLCENEKDLIWT
LRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVR
EFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRS
EMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKLGTIKTKTKQAHL
KEAMMTCLRQTGFIETLSNLHSPLNPNILLAGVHVERCKYMDSKMKPLWIVYHNKLLGGD
TVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSAD
TIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIG
DRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEK
FGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEAL
KQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A8C2GQD0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLWLAEHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLI
TKWNKHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLSDDELFQYL
LQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYC
RGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVV
SPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQDMLTLQMIQL
MDVLWKTEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMISETGQLFHIDF
GHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGT
LFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVN
WMMHTFAKDNR
>A0A8C1A304|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWVESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQNIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKRISEEKMQCMQLMSWGEWLRSCYSMTLEAGSLE
NLIDKHEGVIKITMHYDQSQDTSSLKVSLHCTVTELMDLALKKWQTTHVPEEDIGFRSDY
VLRVSRKLEFLFEDHHLNQCKYIRDCLLTNESPHLTLVHCDVVKAMFEKEISTIGSVLAW
KTSNPPLPLPPKKRLPTQLHTCVWKVHSLFRIHLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHL
NKYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTN
PYTENATELHISFPEYSTQPVVFPAFDKVWNIGPHCRHGRGGKKFYIELKEIMERDPLSQ
LCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALEL
LDFNYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRK
IGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVQHFHWSNLSLLYFIKN
K
>A0A7L2EF74|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anthoscopus minutus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQV
>A0A8D0KPL4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strix occidentalis caurina|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIESLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
NLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGSSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>S9WXM9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Camelus ferus|TrEMBL
MRALGGQVAQGMELENYEPPVVLREDNCRRRRRMKQRSTAASLSSMELIPIEFVLPTSQR
NTKTPETALLHVASHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEI
YDKYQVVQTLDCLRYWKVLHRSPGQIHLVQRSTPSEETLAFQRQLNALIGYDVTDVSNVH
DDELEFTRRRLVTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTT
SQTIKVSADDTPGTILHSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKN
FQWVRQCLKNGEEIHLVLDTPPNPDLDQVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESV
FTVSLWDCDRKFRVKIRGIDIPILPRNADLTVYVEANIQYGQQVLCQRRTSPKPFTEEVL
WNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSGKASAETPSPESKGKAQLLYYVNLLLI
DHRFLLRHGEYVLHMWQLSGKGEDHGSFNADKLTSATNPDKENSMSISILLDNYCHPIAL
PKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAY
PKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLE
SLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHY
QQRFAVILEAYLRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQGMIEIVK
DATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIDEKDVCVKAYLALRHHTNLLIILFSM
MLMTGMPQLTSKEDIDYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLG
IKQGEKHSA
>A0A1A8UZ19|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius furzeri|TrEMBL
VSDEECEVPREEIRRRRRKKAITSSSSISMDQITVEFVLPSAARGGSSSDSLQLEVAGNW
TVEQVKAQLWMKAVTLNFCPDFFQRLSPDHCILLYQKKGTICEIYDKHQVFQTLDCIRYW
RALKKEVGRIQLVPRPQPTDESLQYQRYLNHLIGYDVTDVSNVHDDELEFTRRKLLTPRR
VELSDRDPKLYSMDPWVTHKQLPEHLLTKVNNGYILVVIHVSTSSQTIKVSIDDTPSQVL
TSFFAKTQNKRVLLGIPDNMCESDFVLRVCGREEYLYGEKPLQDFNWIRQCLKGGEEIHL
VLETPPDPELDMVQKEDWAQVDDCTGVTGTHEQLTITEKDHERVFTISMWDCNRKFRMKV
LGIDIPTLPKVPDFTVFVEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKIKDLPK
GTRLNLQVICGKQPQMSSSRGGSYYEATSGTCCPEGKTKNRVLYYVNLLLIDHRSLLRQG
EFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAVAISLDKYCYPVVLPKSRDVGR
DCGAMGEESEGGERGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRHECMRHPRA
YPKLLGSVRWGKQEDVLSTHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVRSIAVRKL
ETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMH
YQQRYAVLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTREVKTMSADKCDITAQVVFQLR
QKLETLQLSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPI
GIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTI
ANIQQSVVGSTGAFKDEILNQWLRDKCVSEDK
>A0A7L2VK92|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Brachypteracias leptosomus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELITIEFILPTSNKHTKVPEMILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTIFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVSKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVVKEAPXKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQD
MLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTGA
FKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLF
HIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAYLALR
HHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGESEENAKKHFLDQIEVCRDKGWT
VQFNWFLHLVLGIKQGVEKHSA
>A0A668VND4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKSKNIKKIFINVKFEASDESFMLQQDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTITKYQEEQGRMCSQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKVPSPKRLHKTVTVKRNYFKLKEIMDNKNYTEFFEDEKELLWKLRTEVRDH
YPESLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLR
KLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASVG
LRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESYL
EALSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLRQ
DMLTLQMIQLMENLWKKEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIR
ETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCER
AYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEA
LRESWKTKVNWMMHSLAKDNRP
>A0A2K5IJ73|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Colobus angolensis palliatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7L0Q3Z0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mesembrinibis cayennensis|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHIPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRTGEQPRAALEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K8UD19|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oceanites oceanicus|TrEMBL
MELGDYEQPVIMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTCNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKIGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDSPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEDQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8D0AM37|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MVVPREATIQHIKLLLWKQAQSHPLFSSLGEMESHMFECVNQAAVHEELEDETRRLCDVR
PFLPVLKLVTRSCGRAERLLDSKIGVLIGKGLHELDAINDQEVKDFRSKMFRLSEERMQQ
VQMMTCTEWLQACFSPQLEPLAGTAITDGLNDRPADLKVIIHFDQSQDSASLKVPSSCIP
SDLMELAVKKWLTTHAPEEEVWLGQYILRVSHCLEFLCGEQPLIQYKVSAKMMSLWSCKD
VMKDFNPHTRTQVQVRAGLFHGTELLCKPAVSSESSGRSDHTWKDSTLEFDLSVCDLPRM
TRLCFAIYAVMDKVKKQKSTKNHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEM
LNPIGTIQTNPYTENATALHIHFPEYSSHSIVFPPFDKVRRLTVPLIITYFLPALGHGVA
AKIVQSPSKLETFIRLLGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFP
QSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLRDM
SDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQ
FALMLEAYCRGNIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMT
CLRQSGYSETLSDLHSPLNPNVLLSGINVERCRYMDSKMKPLWIVYNNKLLGGDTLGIIF
KNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQ
LTSSNVAAAAAFNKDALLNWLKERNTGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQ
YCEEAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEDALKQFRQK
FDEALRESWTTKVNWMAHNVAKDNRS
>A0A8D0AKY6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
VGLENDMTFFLFDQEPKALREDTRRRRRKKAIMSSSCTSMDQISVEFVLPTAARGGNNPD
TLLLEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQV
FQTLDCIRYWRALKKDVGRIQLAPRPQPSDESQQYQRYLNYLIGYDVTDVSNVHDDELEF
TRRKLLTPRRIQLADRDAKLYSMDPWVTRKPLPEHLLSKISNGHILVVIHIGTASQTIKV
SIDNTPAQVLVSFLAKTANKRSLLGIPDNMCEADFVLRVCGREEYLYGDKPLQDFNWIRQ
CLKNGEEIHLVLEAPPDTDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMW
DCNRKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLE
FNIKIKDLPKGARLNLQVVCGKQSQTPNSKGSSAYQDNAIKSRLLYYVNLLLIDHRSLLR
QGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASAMAVAILLDKYCYPVVLPKSRDV
GRDAATGCEEAEGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDP
RAYPKLLGSVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVR
KLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKTALRSKRIGHFLFWFLRSEIAQS
MHYQQRYAVLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTREVKAMSADKCDITAQVVFQ
LRQKLETLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKD
PIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIETVKDAT
TIANIQQSVVGSTGAFKDEILCQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGD
RHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHF
QKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQR
HLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>B0EVF1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Entamoeba dispar (strain ATCC PRA-260 / SAW760)|TrEMBL
MHYNLWNESTIKMMKYFDQFVGNNNWNLIQDETRYLSQRECQTPVCIQIISAEGIKHYKI
TKLKDDSEIVNLEEDVKIYITGSLHYGTRLLVRQEFTPVYQIKEGKLHLNSPIMMTFNIL
ISTLPKETRLTLSIYMTDTPINLPILETNKKDICLATINCKLVDHNGYFMKGLFNVGMWE
RIEPNPIMMCCENTSSNTCKLHYRMIEFNKPVKMNTFTANEQELNTNIIDSIKIDSEHTL
RFKYVVEADPLTILSQEDCRLLWKYRYLVEKTKPGSLARLVSAVDFTQQSEVLELHRLLN
KWPLLKPTQALELLDFRFPDEQVRLFALKCLDAMKDYELVNFLPQLVQALKFELHHQSNL
AYFLLRRALRNKNIIGHQFFWFLKAEMHDNRVTERYGVLLEAFLNGCENYRTELYNEVTF
QNQLVVIANKVKQIEVKEEQKQLLKDSLAKLKYPEEMSLPLDSRFRIKKPVPNTGNVFSS
KKKPLMLVLENVDPLGDNIMVIQKVGDDLRQDI
>A0A7L1QM45|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cisticola juncidis|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVLNSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYSFPLQLEPVAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPREFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSAPKAA
CKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
GEVAVSSEPVWRQRLDFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEERLQLKEILERRSHTELYEHEKDLVWKMRNE
IREQHPQALAKLLIVTKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKSDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A674K8C0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Terrapene carolina triunguis|TrEMBL
SSGEGTGLDWGTGDLLPIWDVMVQPAHRWFHPAVGLSQVVWRHAQYEPLYHMLNDPEAYV
FTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHEFD
SVRDPEVNDFRAKMRQFCEEKAAKRQQLSWMAWMEYNFPLQLEPLAKGPRTGPLRVPNKN
IFVNVKFESGGESFTFQVSPKEFPVMLMSYAIKKQATVFRHQTVESPEDYTLQVKGKCEY
LYGNYPLYQFQYIRSCLHHGLMPHLTMVHFSSIIAMRDEQTNCTAHTPKMVSKPPPLPKK
KVTMRAHRIPFSPCSHQPETPICFFSLVVQAGLYHGNEMLCKMVSSAEVNVCSEPVWKQR
LDFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVSEDCPIAWVNVMLFDYKDQ
LKTGECCLHMWSSFPDEKGELLNPMGTVQSNPNTESAAALVICFPSVLLHPVYYPSFDLA
ASPREQSELPGHFRFRLSPIRSCEQKQQLREILERRSHTELYEHEKDLVWKMRFEIRDQY
PEALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFTINSLKK
LTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPAVAL
RFGLILEAYCRGSNYHMKVLMKQGEALNKMKALNDFIKVSSQKATKPQAKEMMHVCMKQE
TYLEALSNLQCPLNPTVILAEVCVDHCTFMDSKMKPLWIVFNNEEAGGRGVGIIFKNGDD
LRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSN
MAATAAFNKDALLNCEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHI
DFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRDYCEKAYMILRCH
GLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTK
VNWLAHNVSKDNRQ
>A0A8D2Q3I6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Varanus komodoensis|TrEMBL
MMPPAMADALDIWAGDSQIAADGSISLDCLLPTGIYISLDVPRDATICYIKQLLWKQAHS
YPLFHLLLESDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVFQLITRSCDPGEKFDSK
IGVLIGKGLHEFDALQDPEVKEFRIKMRRISEEKMQSLVGLSWMDWLKYTYPAELEPSIQ
DNLQDKLYGGNLVVAIHFDSCQDVFSFQVSPNINPIKLNEMAIRKRLTIHGKEDEEVDPY
EYVLQVSGRLEYIFGDHPLIQFQYIHHCVLNRALPQLTLVECSTIKKMCDQEMVATEAAI
NRKQLNPPLPLPPKKLRAIQSVWDISHPFKVILVNGNKLNTEETAKVHVRAGLFHGTELL
CKPIVSSEISGRNDHVWNEPLEFDISVCDLPRMARLCFVVYAVMKNKKSGRPLNPPKYQT
IRKAGKVHYPVAWVNTMVFDFKGQLKTGDFTLHSWSSFPDELEEMLNPMGTVQTNPYTEN
ATALQIRFQEYSKMPIYYPPFDKILEKAAEIARNSECSAMAGRGGKKFHIELKEIMERDP
LSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWSKLPPREA
LELLDFNYPDQYVREYAVGCLRQMSDEELAQYLLQLVQVLKYEPFLDCALSRFLLEKALA
NRRIGQMLFWHLRSEVHIPAISVQFGVILEAYCRGSIAHMKVLYRQVEALNKMKTLNNLI
KLNAVKQSRAKGKDTMHTCLKQRAYKEALSNIQSPLNPSVLLSELHVEKCKYMDSKMKPL
WIVYNNKVFGGSLVGIIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRILPYGCLATGD
HSGLIEVVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEAFTLSCA
GYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFGRFRQCCEEAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6P8FW08|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Clupea harengus|TrEMBL
MPPRPSSGELWGIHLMPPKILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDVNGPHSRALYVYPPNVESSVELPKH
IYAKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLNRMPNLMLMAKDSLYSQLPVD
NFTMPSYARRISTATPYMNGESSTKSLWTINGMLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLQYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMTVVEDHANWIISREMGYNYCQSGQSSRLARDHAMTESDIEQLRHLCNRDPL
SEITEQEKDFLWRHRQYSANMPEVLPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRFDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A8D2Q950|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Varanus komodoensis|TrEMBL
MDSSEHPVVMRDDNKRRRRRMKPHCTASTLSSTEQITIEFVLPTSNMLIDVASNCTVEQM
KAQVWMRAIERNQTSDFYHKFTPDQFVLHYQKKGQWYEIYDKHQIIQTLDCILYWKVLQK
KVGKIHVVQKQKPTEEAQEFQKQLNYLIGYDVTDVSNVHDDELEFVRRRLVTPRTIEVSC
RDPKLYSMHPWTTSKPLPEYLLTRIINNNIFLNIHRGTTSQKIKVGIDDTPNVILQSFFT
KMAKKKSLMNIPEDNSELDFVLRVSGRDEYIVGETPIKNFHWIRQCLKNGDEIHLLLDEP
PDPNQDEVQKEEWPLVDDFTGVSGYHEQLTIDGKDHERVFTISLWDCNRKFRVKIIGIDI
PVLPRNTDLTVFVEANIQHGQQLLSQRRTTAKPFTQEVLWNAWLEFDVKIKDLPKGALLM
LQVYCGKTPASSTKANLQSNDPPTCDPKCKTQLLYYVNILMIDHRSLLRTGDYVLHMWKI
PGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHKIACDLQGDRVRAEM
PNQLRKQLEEIIATDLLNPLTPEDKELLWHFRYESVKHPKAYPKLLSSVKWGQQEIVAET
YQLFAKKDAWDRSTLDVGLPMQLLDCNFADEHVRAMAVQKLESLEDDDVLHYLLQLVQAV
KFEPYHDSALARFLLRRSLKNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKA
MLQDFMKQVQVTELLHRVTMEIKSISAEKYDVTPQVITQLKQKLEKLQDSKFPECFRVPY
DPGLKAGALVIDKCKVMASKKKPLWLEFKCADPTSLSSETIGIIFKHGDDLRQDMLILQI
LRIMESIWEEESLDLYLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEIL
NQWLKEKCIIEEKFQAAVDRFVYSCAGYCVATFVLGIGDRHNDNIMITESGNLFHIDFGH
ILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLRFQNFQEICVRAYLALRKHTDLL
IILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEAAKKYFLDQIEVCRDKGWTVQFNWF
LHLVLGIKQGVEKHSA
>A0A2U3WRR0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Odobenus rosmarus divergens|TrEMBL
MQGDPEKRKSLEAHWVMSGMELKHHEQPVVLREDNGRRRRRMKPRSSAASLSSMELIPIE
FVLPTSQRNSKTPETALLHVAGHGNVEQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQ
KKGQWYEIYDKHQVVQTLDCLRYWQVLHRSPGQIHVVQRRAPSEETLVFQRQLTALIGYD
VTDVSNVHDNELEFTRRRLVTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIF
IIIHRSTTSQTIKVSADDTPGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYL
VGETPIKNFQWVRHCLKNGEEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTI
HGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSP
KPFTEEVLWNVWLEFSIKIKDLPRGALLNLQIYCSKAPALSGKASAETPGSESKGKAQLL
YYVNLLLIDHRFLLRHGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLD
NYCHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYE
SLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVR
AIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRS
EIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSS
QVISQLKQKLENLQNSNLPESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPT
ALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEI
VKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFV
LGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKK
TSLYFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNE
EEAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A8C6ULF0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neogobius melanostomus|TrEMBL
MSPGKYGMQEEWEKEEAWDQGIMMDFLLPTGIFLKFPVSRNDTIKTIKKMVWKNAKSEAL
FSALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQIS
LLIGKGLHEFEAQKNHEVNEFRTKMRAFCEEKALERQLLPWRLWMEYSFPCDLEPCCSPH
EEGNNKKKNTKIFVNIKFEASEESFMLQQDPQDLPMALVKSALKKKATVFRSVRQEPEDY
TLQVNGRWDFIYGDHPLCQFKYMFSCLRNGQAPQLTMVHHSTISKYQEEQGRMSNQLFQS
RSLSRPPPLPLKKNTSSLWSINEPFYIQLLHGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVRSEPLWDQKLEFDISVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKRADCPI
AWVNTMVFDYKDQLKTGEFLLSAWPSVPGTNRLILSKSVSTASSTAPVSACSGLKNPVWH
VALAHILSVRDFLEFQLLRLKEIMDNKNYTEFFEDEKELLWKLRYEVRERYPESLSKLLL
ITKWNKREEVVLMVSLLRNWPDLPAIQALELLDYSFPDPSVRSFTIRCLKKLSDPELLQC
LIQLVQVLKYESYLDCDLTTFLLERALSNQRIGHFLFWHLRSEIHVSSVGLRFGLILEAY
CRGNIHHIKLLTKQNEALTKMKALSDIVKSGSHKMTVDDLKLCIRQESYMEALSDLLSPL
NPSIILTQICADKCRFMDSKMKPLWMMYRNPCFQGEMVGIIFKNGDDLRQDMLTLQMIHL
MENLWKKEGLDLRLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGH
FLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEWAYKILCHNGILF
VNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWM
MHSLAKDNRP
>A0A8C5SK55|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Laticauda laticaudata|TrEMBL
MPPRPSSGELWGMHLMPPKILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGQI
IVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKY
ILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMTKESLYAQLPLDTFAMPSYSRR
ISTATPYMNGEASAKSLWAINSHLRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDN
VNTQRVPCSNPRWNEWLQYEMLVHDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINMF
DYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSPVKFPDMS
VIEEHANWIISREQGFNYNHAGLSNRIARDNELRDNDKEQLRAICTRDPLSEITEQEKDF
LWSHRHYCVSMPEILPKLLLSVKWNSRDEVAQMYCLIKDWPQIRPEQAMELLDCNYPDPM
VRAFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWH
LKSEMHNKNVSQRFGLLLDSYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKV
QMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLWLNWENPDIMS
ELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEV
VRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDPAIDLFTRSCAGYCVATFI
LGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQE
CTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDK
TEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A1U7UN95|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carlito syrichta|TrEMBL
MCFSVTMPPAMADVLDIWAVDSQIACDGSIPVDFLLPTGIYIQLEVPREATIAYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRQFSEEKIQSLVGLSWMDWLKHTYPPEH
EPSILENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMNPLKINELAIQKRLTIHGKEED
ASPCDYVLQVSGRVEYVFGDHPLIQFQYIRTCVINRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKTRVISHIWENNNPFQVVLVKGNKLNTEEAVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCLAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVQHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTV
QTNPYTENATALHVKFPESKKQPYCYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLK
EILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWP
KLPPREALELLDFNYPDQYVREYAVDCLRQMSDEELAQYLLQLVQVLKYEPFLDCALSRF
LLERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKL
KTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYM
DSKMKPLWLVYTNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPY
GCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIE
EFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFI
LTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLVLRRHGNLFITLFALMLTAGLPELTSVK
DIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C9LDS0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pavo cristatus|TrEMBL
MKPHCTSSNLSSMELITIEFILPTSNKHTKAPEMMLLEIAGNCTVEQMKAQIWMRAIEVS
QTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLDCILYWKVLQKKVGKIYVVQKQK
PSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRLVTPRMIEVACRDPKLYAMHPWT
TSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDTPDMILHSFFTKMAKKKSLMDIP
EDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNGEEIHLVLDNPPDPSEDEVQKEE
NTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKIKDLPKGALLNLQIYC
GKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRSGEYVLHMWKIPGKGE
EQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSDSQGDRTRAEMPNQLR
KQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQEIVAKTYQLLA
KKEVWDQSFPTDCCVVSLACKRALHMLLTRLLCIFQAVKFEPYHDSALARFLLKRGLRNK
RIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLHDFMKQVQVIELLHKFLFLL
SLSYLKAVSDLHVSLRFISDLEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYAVERFVYSCAGYCVATFVLGIGDRHNDNIM
ITETVNEDVYLMEPLPWSCTTPLSLNCREMQLGRP
>A0A2P4THH8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bambusicola thoracicus|TrEMBL
MEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLDTIKQVVWKHAQYEPLYHMLSDPEAY
VFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHEF
DSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGAGLLHTPIK
NIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYTLQVNGKYE
YLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQVNSIANPPKMAVKPPPLPK
KKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVNVCSE
PVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDY
KDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNVASHPVYYPSF
EQLLELGRNGEQPRSAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQA
LAKLLTITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTD
HELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFG
LILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQETYL
EALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQ
DMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAA
TAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQ
LFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYMI
LRRHGPLFLHLFALMKAAGLPELTCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRES
WKTKVNWLAHNVSKDNRQ
>A0A4W4HEK6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MPPGVCYGMQDVWEKGGREQVTLEFLLPTGIYLSFPVARNDTIGTIKKMVWKNARSEPLF
SVLSDPDAYVFTCINLTAEREELEDESRRLCDVRPFMPVLRLVAREGDRVEKLINTQISL
LIGKGLHEFDTQKNHEVNEFRAKMRSFCEENAQDRQRLPWHQWMKCNFPCDLEPFSMVVQ
SGKSCSVKKLLVNVKFEASEESFMLQLDPQDFPVVLMQNALRKKATVFRPLKQEKPENYT
LQVNGRWQFIYGNSPLCQFKYIFSCLYGGIKPHLTMVHHSTIIKYQEEQGGLSNQVSKSR
SLSKPPPLPLKKQNTSSLWSIKEPFFIQLVHGTRVNTDEGMKLVVQAGLFHGGELLCKVV
TSSEVSVCSDPVWDQKLVFDINLCDLPRMSRLCFTLYGVLEKTKKQRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSAPDDKGDLLNPMGTVERNPNIDSTAGLLIRFPSF
RPHPLYYPPLEKVNRTSVRIHKTEGIGQHLKLKEIVDNKNHTEFFEHEKELLWKLRLDVR
AHYPESLSKLLLITKWNKHEDVAQMVCLLRTWRDLPPLHALELLDYTFPDPHVRSFTIRC
LKKLGDEELFQYLLQLVQVLKYESYLDCDLTTFLLERALSNKKIGHFLFWHLRSEMHVAS
VSLRFGLILEAYCRGSIYHIKSLMKQIEALNKMKALNDFVKSGSQKSASRLQITEDMKLC
IKQDTYMEALSDVISPLSPSIVLSEICPDRCKFMDSKMKPLWLMYKNKWDHLDTVGIIFK
NGDDLRQDMLTLQMIQLMDVLWKTEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMIRENGQLFHIDFGHFLGNFKAKFGINRERVPFILTYDFVHVIQQGRTNNSEKFER
FRECCEQAYKILCRNGTLFVNLFALMRAAGLPELSCSKDIQYLKDSLALGRSEEEALKNF
KVKFNEALRESWKTKVNWMMHTVAKDNR
>F8W9P4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSAQTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNP
TGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKLPGGMLLASREWRPELLWMRLHAED
SAPSRMIGVAMPGLGVLPGLVQAPGDAECSRLLQILELGRHSECVHVTEEEQLQLREILE
RRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPV
LSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDR
ALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2K6RRD5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinopithecus roxellana|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAIYAVLDKVKTKKSTKNI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIMLHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8D1KCB8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MIVTLECLREATLVTIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRL
CDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKE
AVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTL
KINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQ
YKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRRISTATPYMNGETSTKSLWV
INSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNY
DIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVP
HGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYS
HAGLSNRLARDNELRENDKEQLRAICTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLL
LSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLS
QYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLE
SYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKMKFLVEQMRRPDFMDALQGF
LSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDM
LTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQ
FNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFH
IDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAI
RQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGW
TTKMDWIFHTIKQHALN
>A0A8D1VQB8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPGVDCPMEFWTKEENQSVDVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSDPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNRHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYAILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKEPNSHKRKRALRAGQGHCSPS
EPWAL
>A0A3Q7VPI0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus arctos horribilis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8D1XLN6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPGVDCPMEFWTKEENQSVDVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKVGLLGWEGDGNVCFLHKHGG
CGLGVAEEEGGSHESHLTTLPGIPAWGGCELIQNRKRGGSRPASQGADSEKPGPLVVQAG
LFHGNETLCKTVSSSEVSVCSDPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARS
TKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRSNPNTE
SAAALVIFLPEVAPHPVYYPSLDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEH
EKDLVWKMRHEVQEHFPEALARLLLVTKWNRHEDVAQMLYLLCSWPELPVLSALELLDFS
FPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHF
LFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKT
TKPQTKELMHLCMRQETYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVMYSNE
EAGSDGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIE
VVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVAT
YVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGK
TNNSEKFERFRGYCERAYAILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGK
TEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A480L2C3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQVGAALARGIYLHVHRQPIQLSSNALCPKSRDQSK
>A0A452HBD9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gopherus agassizii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVCPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWVINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMTVIEEHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C1Y1H0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSPELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLARLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKFPDMATIEDHANWIISREMGYNYCHYLIFRLARDHAMTEADIEQLRQLSNRDPLS
EITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMEL
LDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQ
RIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQ
EKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWL
NWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSI
GDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNRGEMYDMAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A6P6KYP6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carassius auratus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGSHSRALYVYPPNVESSSELPKH
IFGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLNRLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKYPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTEADIEQLRQLSNRDPL
SEITEQEKDFLWRHRQYCVNIPDILPKILLAVKWNSRDEVAQMFCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMKRPDFMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNRGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A2Y9RH31|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Trichechus manatus latirostris|TrEMBL
MDLQNDEPPVVLRADNFRRRRRMKPRSTAASLSSMELIPIEFVLPTSHRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRFGPDHFLLLYQKKGQWYEIYDRYQVVQTLD
CLRYWKVLRRSPGQIHVVQRHAPSEETLAFQRQLTALIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLSKKIANNCIFLVIHRSTTSQTIKVSADDT
PDTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSSESKGKLQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKYPKAYPKLFSSVKWGQ
QETVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSVEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSKETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEILNHWLKERCPLEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPYFQKFQDVCARAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKHGEKHSA
>A0A8B6YA75|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Camelus ferus|TrEMBL
MCFHSIMPPAMADILDIWAVDSQIGSDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRSTIHGKEDE
VSPHDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFHIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASNDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVMLSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>K7DEK7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan troglodytes|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRALPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6D2Y2J7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan troglodytes|TrEMBL
MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYKLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A6J3JIN8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sapajus apella|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWSEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSISREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8B7I7C7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcebus murinus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSCNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARGWGA
GTLRLPNRAFLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGRHEYLYGSHPLCQFQYIRSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQGQKPR
AKPPPIPVKKPSSASLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRGNPNTESAAALVICLPEVAP
HPVYYPALEKILDLGRHSECGRVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTRFLLDRALANRRIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDLVKASSQKNPKPQTKEMMHMCMR
QDAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEQAGGGGCVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C5W077|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcebus murinus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSCNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARGWGA
GTLRLPNRAFLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGRHEYLYGSHPLCQFQYIRSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQGQKPR
AKPPPIPVKKPSSASLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRGNPNTESAAALVICLPEVAP
HPVYYPALEKILDLGRHSECGRVTEEELQLREILERRGSGELYEHEKDLVWKLRHEVQEH
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTRFLLDRALANRRIGHFLFWHLRSEMHVPSVA
LRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDLVKASSQKNPKPQTKEMMHMCMRQ
DAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEQAGGGGCVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>D2GUC9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ailuropoda melanoleuca|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A6P3E0C7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ovis aries|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3Q2ZIW7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Kryptolebias marmoratus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDKITVDFLLPTGIFIQMDVPREATIQHIKLLLWKQAQ
TFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVMRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRVCEEKMQRAQLLTCAEWLQACFSPQLEPA
AVTAIRDGVNDRPPDLKVIIHFDQSQDSTSLKVSSSCTTSELMEMAVKKWLTTHAPEEEA
WRGQYFLRVSQRLEFLCGDHPLTQYKYIRTCLQAKEPPHLTLVHTSTVKAIFDKEMSAIG
AVVSRKSSNPPLPLPPKRRAPTQVQTCVWDVSSPFRIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESNGRSDHTWKDSTLEFEISVCDLPRMTRLCFAIYAVMDKVKKQKST
KNAHINKYPTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHSIVFPPFDKILEKAAQIIKASDCAPKGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRHDCHENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLGPRDALELLDFNYPDQYVREYAVRCLSDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALS
KLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSEALSDLHSPLNPSVQLSDI
SVEKCRYMDSKMKPLWIVYNNKLMSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAN
LDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVVAAAAFNKDALLNWLKERNSG
DALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRRNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A671F1N2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinolophus ferrumequinum|TrEMBL
MPPGVDCPMEFWTKEENQTVAVDFLLPTGVYLNFSVSRNANLSTIKKVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLSWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSMSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALIICLPEVAP
YPVYYPALDKILELGRHGEHCRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSL
RKLTDDEVFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSIHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPHTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYNNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A6J2M3E3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phyllostomus discolor|TrEMBL
MCFNFIMPPAMADILDIWAVDSQIPSDGPIPVDFLLPTGIYIQMEVPREATISYIKQMLW
KQIHNYPMFSLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWIEWLKQTYPPEH
EPSNLENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQISGRLEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNFPLPLPPKKTRIISHVWENNSPFQIVLVKGSKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NASKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSKRIQSRIGKGKRFMGQSLEETSDEELSQY
LLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVHIPAVSIQFGVILEAY
CRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDL
QSPLNPCVILSELHVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQ
MLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNK
DALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDF
GHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGN
LFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEDEALKQFKQKFDEALRESWTTKVN
WMAHTVRKDYRS
>A0A7K5Y9D1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pterocles burchelli|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTVDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHGELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPILPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHECPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>H3D9Z7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tetraodon nigroviridis|TrEMBL
LRWRAVLLAMPPAMTDLLDIWATHTPLAGHAPDQITVDFLLPTGIYIQFDVPREATIQEI
KQLLWKEAHSFPMFSKLGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRN
CGRAERLLDSKIGVLIGKGLHELSAINDQEVKDFRCKMARISEERMRKIERMTYAEWLQA
SYSPQLELTADPAVMEGNDRPADLKVIIHFDQSQDSASLKISSTCSPKDLIAQAVRKWLT
THGPEEETLKGQYVLRVSHCLEFLCGDHPLIQHKQYIRTCLQAKEPPHVTLIHNNTVRAM
FNREISAIEAALTPKSSNLPLPLPPKKRAPTQVQTCVWDVSSPFRIVLVNASKVNAEETA
KVQVRAGLFHGTELLCKPAVSSESSGRSDHATLEFELPVCDLPRMTRLCFAIYAVMDKVK
KQKSTKNTHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEM
LNPIGTVQTNPYTENATALHISFPEFSSHPIIFPPFDKILEKAAEIVGASDYASMGRGGK
KFHIELKEIMERDALSQLCENEKDLIWTLRCDCRENFPQSLPKLLLSVKWSKHEDMAQLQ
ALLQIWPRLSPRDALELLDFNYPDQYVREYAVNCLRDMSNDELSQYLLQLVQVLRYEPYY
DCALTHFLLERAQSSRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQ
VEALNKLKAVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGFSETLSDLHSPLNPNI
LLSGINVEKCRYMDSKMKPLWIVYNNKLLLGDMLGIIFKNGDDLRQDMLTLQILRLMDTL
WKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNMAAAAAFNKDALLNWLK
ERNSGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSNGQLFHIDFGHILGNFK
SKFGIKRERVPFILTHDFIHVIQQGKTGQAEKFGSFRQYCEKAYLILRKNGNLFITLFAL
MLTAGLPELTSVKDIQYLKDSLALGKSDDEALKQFRQKFDEALRESWTTKVNWMAHNVAK
DNRS
>A0A6J0X4H8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Odocoileus virginianus texanus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSMSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTSEMHVPSVSLRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTK
PQTKELMHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEA
GSDGAVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVV
LHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYV
LGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTN
NSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTE
EEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K8Q572|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Menura novaehollandiae|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHGTSSNFSSMELISIEFILPTSNKHTKGPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQATDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEIQEFQQQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEGVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
QLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C2M6Q8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cricetulus griseus|TrEMBL
MCFSSMMPPAMADILDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLW
KHVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEDKIQSLVGLSWIDWLKHTYPPEH
EASVLENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNLTPIKINELAIQKRLTIHGNEDE
VSPYDCVLQVSGRVEYVFGEHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYAENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANMSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALNNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLRQNAYREALSGLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYSNRGFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRRDYRS
>G3I7G5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cricetulus griseus|TrEMBL
MPPGVDCPMEFWTKEESQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVDDFRTKMRQFCEEVAAHRQQLGWEDWLQYSFPLQLEPSARSWRA
GILRVTNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGRHEYLYGNYPLCQFQYICSCLHSGLTPHLTMVHASSILAMRDEQSNPAPPVQKPR
TKPPPIPAKKPSSVSLWSLEQPFCIELMEGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWRQRLEFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSRKADCPIAW
ANLMLFDYKDQLKTGERRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAP
HPVYFPALEKILELGRHGEQRGRITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQ
EHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKS
LRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPS
VALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCM
RQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGSVGIIFK
NGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQL
NKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRESGQTML
>A0A672U5Z2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVHDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQVCKALWNLPQQFSGPLSVWDISNPFKIILLKGNKLNTE
ENAKVHVRAGLFHGTELLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYA
VMDKMKTKKSTKHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYAKHYFTCNLRIFFLKQLQALLQIWPKLLPREALELLDFNYPDQY
VREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQMLFWHL
RSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAMKQSKAKG
KDAMQTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKPLWIVYNNKMFGGD
LVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATGDHSGLIEAVSSSE
TIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSCAGYCVATYVLGIG
DRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEK
FGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLKVKYDLQLSGTFQY
VNFDTKMNTF
>A0A4U1ES19|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodon monoceros|TrEMBL
MPGSTKDKHGQNTTASTGTLTKLDTVEKEKYAAWKANVITINKDQLRPYTAQNIPTFYLS
SQGMNGAAQDKVAEGMELENHEQHVVLREDNRRRRRRMKPRSAAASLSSMELIPIEFVLP
TSQRNTKTPETALLHVAGHGNVEQMKAQVWLRALETSVAADFYHRLSPDHFLLLYQKKGQ
WYEIYDKYQVVQTLDCLRYWKVLHRSPGQIHVVQRLAPSEETLAFQRQLTALIGYDVTDV
SNVHDDELEFTRRRLVTPRMAEVAGRDTKLYAMHPWVTSKPLPEYLLKKITNNYIFIVIH
RSTTSQTIKVSADDTPGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGET
PIRNFQWVRQCLKNGEEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKD
HESVFTVSLWDCDRKFRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFT
EEVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVN
LLLIDHRFLLRHGEYVLHMWQLSGKAEDHGSINADKLTSATNPDKENSMSISILLDNYCH
PIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKD
PKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCSFSDENVRAIAV
QKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQ
SRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIDMLQKVTMDIKSLSAEKYDVSSQVIS
QLKQKLEILQNLNLPQSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSN
ETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDA
TTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIG
DRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSRH
FQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAK
KYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A8C7H973|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGMVWRNASSEPLYGALSD
ADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFDSQKNHEVNEFRVKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEPGGIK
TKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDYTLQV
NGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQLSKSRSLS
KPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVVTSGE
VNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPLAWVN
TMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIHFPNIRPHP
LYYPHFDKMVTFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQL
VQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGN
IYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYKDALSYLLSPL
NPSIKLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIFKNGDDLRQDMLTLQMIQL
MEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALL
NWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFL
GNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVN
LFAMMKAAGLPELSSFKDIQYLKCPFQNMAMIW
>A0A8C7JEG8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLTNIKQQLFTEARKYPLYP
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFEQLKDPEVQDFRRSILGVCREAMEEREGGGAETQALYVYPPNVESAPRAATT
HLLQTGQGLKYTLKISHDSLPEQLIAEAIRKKTRSMHLSAQQLRLCVQEYQGQYILKVCG
CDEYLLEKYPPQSYIRSCITVGRLPHLMLVSKDSLYSQLPGSGFVAPSYSRRTPQPSPCP
GGGDPSSPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRV
PCSNPRWNEWLSYDIYMTDLPHSARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYKDTL
VCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFSWFNQVVLFPDEQQIEEHA
NWTISRELGYNYSLGLSSRLACDSSVSAADGEQLRSLCSRDPLYELSEQEKDFLWRHRHY
CVNIPESLPKLLLSVKWNSRDEWSQMYCLLRDWPLMQPEKFALRCLVQGLTDDKLSQYLL
QLVQVCLSVCLCTWTNPLARFLIKKALTNQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAF
CRACGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQKTQMKFLVEHMSRPDYMESLQGF
VSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWDNPDIMSELLFTNNEVIFKNGDDLRQDM
LTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVKNSYTIMQIQCKGGLKGALQ
FNSHTLHHWIKDKNRGEGYDRAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFH
IDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQECTKTKEFERFQEMCYKAYLSI
RQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGW
TTKMDWIFHTIRHIHKESPI
>A0A8C7HGR9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHEVFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKCPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGESSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRYYRHTTHMGDSLWLCLSPRWNEWLTYDMYIPDIPRAAR
LCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGV
TGSNPNRETPCLELEFDYFSSPVKFPDMTTVEGHANWTISRELGFSYYHALTDSDNEQLR
QVCNRDPLSEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPA
IKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVVKYEQYLDNPLVRF
LLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKL
INLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNIRLEECRIM
SSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLR
MLPYGCMSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDL
AVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERV
PFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPE
LQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A7L1YZQ6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scytalopus superciliaris|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAARRQQLGWAAWMEYNFPLQLEPLAKGFGT
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKVQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMIFLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q1MD55|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos taurus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAILELGR
LGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQEHFPEALARLLLVTKWN
KHEDVAQMLYLLSSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLV
QVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGST
HHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLD
PSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKNGDDLRQDMLTLQMIQL
MDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALL
NWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFL
GNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLH
LFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAH
NVSKDNRQ
>A0A8C0FPH5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
ESEEKEYEQSYGSAKDLWEQDSVEKISEKFLALVTDFMLLGSHPAVGLAQVVWKHAQYEP
LYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQI
SLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKA
LCWHLTVYAVLLALQESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYTLQVNG
KCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMAAKPPP
LPKKKVKESSDPHVSSANRSSPCGFMVFPYFSFPQLVVQAGLFHGNEMLCKTVSSSEVNV
CSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVSEASDCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQVGDQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIIT
KWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDQYVGSFAINSLKKLTDHELFQYLL
QLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCR
GSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHVCMKQETYLEALSHLQS
PLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMI
QLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDA
LLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGH
FLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLF
LHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWL
AHNVSKDNRQ
>A0A836AQG2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ovis aries|TrEMBL
MRLEPWSFEEPRATKARTSESVILHGANDFMCDKMQRSLHDALCVVERVLESKSVVPDES
SYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVC
EFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLD
KGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEY
QGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPS
YSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEP
LCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGN
INLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKF
PDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPLSEITEQ
EKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNY
PDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHF
FFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDE
TQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENP
DIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVG
LIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCV
ATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISK
GAQECTKTREFERLFPKSVDGQNLKVKFVWKQTGFAFSYHKPCERLYEKLKTSKTPCEEI
ISYMIFSGTFVKLTKTSVNMLGTVEPYIVLGYPNLKSINELICKHGYGKINKKQIALMGN
KLIARSLGKYGIFCMEDLIHEICTAGNCFKEGNNFLWPFKLSSPQGGMKKKTTHFAESGN
ADNREDQINRLITRMN
>A0A8B7A5T6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Orycteropus afer afer|TrEMBL
MDLENYEPPVVLRGDNCRRRRKMKPRSTAASLSSMELIPIEFVLPTSQRNSKTPEIVLLH
VAGHGNVEQMKTQVWLRALETSVVADFYHRLGPDHFLLLYQKKGQWYEIYDRHQVVQTLD
CLRYWKMLHRSPGQIHVVQRRAPSEETLAFQQQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVARRDPKLYAMHPWVTSKPLPEYLLKKIINNCIFIIIHRSTTSQTIKVSADDT
PGTILHSFFTKMAKKKSLMDIPETQSEQDFVLRVCGRDEYLVGEIPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKGHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSTESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISEKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEMVAKTYQLLARKEVWDQSTLDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKHGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQIIETLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQVSRTWKTGLRSESPLSLTQQKHGRSSFGLGPRPQSTSDSVHPHVGMIEIVKDAT
TIAKIQQSTVGNTGAFKDEVLNHWLKEKCPLEEKVSSGNLFHIDFGHILGNYKSFLGINK
ERVPFVLTPDFLFVMGTSGKKTSPHFQKFQNVCVRAYLALRHHTNLLIVLFSMMLMTGMP
QLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKH
SA
>A0A8B9IS44|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amazona collaria|TrEMBL
MELEDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAANCTVEQMKAQIWMRALEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQNPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKVKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDPKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRIRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEIWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQGYALRIFSQVYTRMGFLRGFLGTAVKFEPYHDSALARFLLKRGLRNKRIGHF
LFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSA
EKYDVTSQVIAQLRQKLEKLQSSKLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLE
FKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGN
KIGMIEIVKDATTIAKIQQSTVGNTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAG
YCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFV
MGTSGKKTSLHFHKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDA
LTVGKSEEDAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C5I7K7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
MPPGKYGMQEEWEKEGDQEILMDFLLPNGIFLNFLVSPNDTIKTIKKMVWKNARNEALFN
GLGDPEGYVFTCINQTAVREELEEESRRIRDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRSKMRSFCEEKAQKRQGLPWQQWMEYSFPCDLEPCSAKSKN
KKKIFINVKFEASDESFMLQQEPQDLPLALMRSALKKKATVFRSLRQEPEDYTLQVNGRW
EFIFGKHPLCQFKYIFSCLRNDENPQLTMVHHSTISKYQEEQGRMCNHIYRSCAMSRPPP
LPQKKQNTSSLWAINKPFNIHLLQGSRVNADEGMKLVVQAGLYHGSELLCKVVTSSEVTV
CSEPLWDQKLDFDINVADLPRMSRLCFALYAIIEKAKKPRGTKKKNKKADCPIAWVNTMV
FDHKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFPNILPHPLYY
PPLDKICVTEENGETVFANKEEYTKLKEIMDNKNHTEFFEDEKELLWKLRTDIRDCYPES
LSKLLLITKWNKREDVVQMVSLLESWPELPAIHALELLDYSFPDPAIRSFTIRCLRKLRY
DDELLQYLIQLVQVLKYESYLDCVLTTFLLERALANRRIGHFLFWYLRSEIHVASVSLRF
GLILEAYCRGNIHHMKVLTKQNQALVKMKALNDFVKSGSQKMTVEDLRLCVKQESYMEAL
SDLLSPLNPSVILAEICADKCRFMDSKMKPLWLMYRNPWPHADMLGIIFKNGDDLRQDML
TLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQLNSSTSAATAA
FNKDALLNWLKSKNPEDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFH
IDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGKTNNSEKFERFREYCERAYKILCR
NGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEDEALKNFKVKFTEALRESWKT
KVNWMMHSLAKDNRP
>A0A851DW18|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dryoscopus gambensis|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGSYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPAKAA
CKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKMLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGVIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6A4SDW8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MTDLLDIWAAHSPLAGHAPDQIPVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQTLPF
FAALGDMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVMKLVMRNCGRAERLLDSKIG
VLIGKGLHELDAMNDQEVKDFRSKTFRISEERMQGVQMMTCTEWLQSCFSPQLEPDVADG
AADWSADLKVIIHFDQSQDSASLKVPSSCTTTELMELAVRKWLTTHGPEEEAWRSQYVLR
LSQCLEFLCGNHPLIQYKYIRTCVQAKESPHLTLVHNSTVKALFDKELSTIGAVVSRKSS
NPPLPLPPKRRVPTVVRKHRYLLLLRRRCRCRCCCCCCCQDIDDIAPRYVRPHFKCQQVQ
TCVWDMSSPFKIVLVNASKVNAEETAKVQVRAGLFHGTEVLCKTAVSSESSGRSDHTWKE
STLEFDIPVSDLPRMTRLCFAIYAIMDKVKKQKSTKNTHINKYQTIRKAGKVHYPIAWVN
TMVFDYKGQLKTGDINLHCWSSFPDELEEMLNPIGTIQTNPYTENATALYIHFPEYSSHP
VIFPPFDKILEKAAEIAGASDCFPAGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLR
WDCLVNFPQSLPKLLLSVKWSKHEDMAQLQALLQMWPKLSPRDALELLDFNYPDQYVREY
AVRCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGNRKIGHFLFWHLRSEI
HMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGPTKNARSKTKDAM
LTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSGINVERCRYMDSKMKPLWIVYNNKLLG
GDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRSSLLFLRTRRIVPYGCLATGD
RSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNTGDALERAIEEFTLSCA
GYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIH
DSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A2J8US94|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pongo abelii|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNMDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A2J8WGP5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pongo abelii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSH
>A0A2J8US95|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pongo abelii|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNP
TGTVRSNPNMDSAAALLICLPEVAPHPVYYPALEKLLGGMLLASRGWRPELLWMCLHAQD
SAPSRTIGVAMPCLGVLPRLVQAPGDAECSCLLQILELGRHSECVHVTEEEQLQLREILE
RRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQDALPAVSWPELPV
LSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDR
ALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A673IBQ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYSMPLEAGSLE
NLIDKHEGVIKITMHYDQSQVCSVNLVCITELMDQALKKWQTTHGPEEDIGFRSDYVLHV
SGKLEFLFEDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIGSVLARKTSN
PPLPLPPKKRLPTLHTCVWKVHSLFRINLVKGNKVNAEDAIQVRAGLFHGTELLCKTAVS
SESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKPRSTKNTHLNKYQTIRK
AGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWTSFPDELEEMLNPIGTIQTNPYTENATE
LHINFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMERDPLSQL
CENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELL
DFNYPDQYVREFAVYCLQDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERSQSSRKI
GHFLFWHLRSEMFMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFGT
IKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGINVERCKYMDSKMKPLWI
VYNNKLLEGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHS
GLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGY
CVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVI
QQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSL
ALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIDYVYATSPF
>A0A673MVL2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MEHQASDDEPPVVRREENKRRRRKMKAFTSTSAVLTDQIAVEFVLPTTNKNSKNPDTLHL
DVTGNWTIEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVVRQQPTEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLSPRKIELSDRDPKLYSMDPWITTKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKN
GEEIHLVLERPPDPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERG
QREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEA
VAITHCLLERSTIWDRSSLDVGLALQLLDCHFSDENVRTMAVRKLETLEDDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALGSMRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRG
CGEAMLQDFRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDSF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLCEKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFLGISKERVPFVLTPDFLYVMCTTDKKSSPNFLQFQVRSYYFTC
>A0A8J4N7T8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eudyptes sclateri|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEERGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2J8QY32|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan troglodytes|TrEMBL
MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYKLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A2J8KXR4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan troglodytes|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNP
TGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKLPGGMLLASCEWRPELLWMRLHAED
SAPSRMIGVAMPGLGVLPGLVQAPGDAECSCLLQILELGRHSECVHVTEEEQLQLREILE
RRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQDALPAVSWPELPV
LSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDR
ALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C9DUR5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Prolemur simus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSCNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARGWGA
GTLRLPNRAFLVNVKFEGSEESFTFQVSTKDAPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGRHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQGQKPR
TKPPPIPVKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVGPRLV
PEPRGELLNPAGTVRGNPNTESAAALVICLPEVAPHPVYYPALEKILELGRHSECGRVTE
EEQLQLREILERRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQML
YLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYL
DCELTRFLLDRALANRRIGHFLFWHLRYSEMHVPSVALRFGLILEAYCRGSTHHMKVLMK
QGEALSKLKALNDFVKASSQKTTKPQTKEMMHVCMRQEAYLEALSHLQSPLDPSTLLAEV
CVEQCTFMDSKMKPLWIMYSNEQAGGNGCVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQE
GLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNP
GEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFG
INRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAA
GLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A1A8EBJ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius kadleci|TrEMBL
MPPAMTDLLDIWASHSPLAGHALEKITVDFLLPTGIYIQMDVPRDATIQHIKLLLWKQAQ
NFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRITEEKMQQAQVMTCTEWLQACCSPQLEPT
AVTLVTDGVNDRPADLKVFIHFDQSQDSTSLKVPMSCTPSELMEIAVKKWLTTHAPEDEA
YSRQYVLRVSQCLEFLCGDHPLIQYKYIRNCLQAKESPHLTLVHTSTVKTMFDKEMSAIG
AVVSRKSSNPPLPLPPKRRPPTQVQTSVWNVSKPFRIDLLKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSDSSGRSEHTWKNNTLKFELSVSDLPRMTRLCFAIYAVTDKVKKQKST
KNAHSSKYQTIRKAGKVLYPIAWVNTMVFDYRGQLKTGDVILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHPVIFPPFDKILEKAAQLVGVIEQPIGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVSCLHDMSDEELLQYLLQLVQVLRYEPYYDCPLTH
FLLERAQRNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSEALSDLTSPLNPSVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLMSGDALGIIFKNGDDLRQDMLTLQILRLMDLLWKESNL
DLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVAT
>A0A7K5T805|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Urocynchramus pylzowi|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFLIIHRGTTSQKIKVSIDDT
PDKILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLHESSNSDAKCKTQLLYYVNLLLIDHRFLLRSGE
YVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSDPQ
GDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVKWG
QQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLDDDDVLHY
LLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEA
YLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGSKL
PESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLR
QDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNT
GAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGN
LFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAYLA
LRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDKG
WTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L3L0B3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Turnix velox|TrEMBL
MPPGTYCPMEFWSKGENQNIQVDFLLPTGIYLSLFVSCSASLATIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRIKMCQFCEDRAAKRQQLTWAAWMEYNFPLQLEPTTKGSGT
GPLHSPTKNIFVNVRFQSGGESFTFQISPEEFPVTLISYAIKKQATVFRHEIMEKPEDYT
LQVNGKYEYLYGNYPLSQFQYIRSCLHRGLTPHLTMVHASTIIAMRDEQSSCISSPPKMA
AKPPPLPKKKPVCGSLWSLEQPFYIHLIQGSKVNADERMKLVVQAGLFHGNEMLCKTVCS
SEVNVCSEPVWKQRLDFDIHVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGEFLNPMGTVQCNPNTESAAALVICFPSLSS
HPVYYPSFEQLLELGRHGGQPRAAPDDPEERLQLKEILERRTHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIVTKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGRDGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQQGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGNALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIQETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCEKAYMILRHHGLLFLHLFALMKAAGLPELSYSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>I3J293|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKSKNIKKIFINVKFEASDESFMLQQDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTITKYQEEQGRMCSQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKICDMERNGDLSLANKEEYFKLKEIMDNKNYTEFFEDEKELLWKLRTEVRD
HYPESLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCL
RKLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASV
GLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESY
LEALSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLR
QDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSA
ATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYK
ILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKVCHSNDVAVNDYEENNNNVNNLWFLV
FKRTL
>A0A669DEU1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRCKMFRISEERMQQIQMMTFSEWVQACYSPQLEPA
AVTAITAGVNDAPADLKVIIHFDQSQDSASLKVSLSCTPNELMEQALKKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKDTPHLTLVHTSAVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRRTCVWDVPKPFRIVLVKGSKVNAEETAKVQVRAGLFHGTELL
CKPAVSNESSGRSEHTWKDNTLEFEISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNPHIN
KYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATALHIHFPEYSSHPIVFPPFDKVTQHSIHSSDCYMVGRGVKKFYMELKEIMERDP
VSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDA
LELLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQR
NRQIGHFLFWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQVEALSKLKSVNELI
KLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDINVEKCRYMD
SKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYG
CLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
THDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A3P9N196|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia reticulata|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFIEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIMSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLENFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCENVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVSLFDYMDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
RFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAADAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCLNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVEAMDKLVNLTDTLKQEKKDET
QKTQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPD
IMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDRVGL
IEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNHGEAYDRAIDLFTRSCAGYCVA
TFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKG
IQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLMLGCGMPELQSFDDIAYLRKTLA
LEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A8C8CCP4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPRPSSGELWGMHLMPPSIMVDCLLPNGMILTLECTREATLISVKHELFKEARKYPLCD
LRLFQAFLKVIEPVEIGMSLVFFIQSFAIGMPICEFDLVKDAEVQDFRRNILNVCKESVD
LRDTNGPISRALYVYPPNVESSVELPKHIFNKLDKAYICINLQKYTLKINHDCVPEHVIA
EAIRKKTRSMLLSHEQLKMCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRM
PNLMLMAKDSLYSQLPIDTFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCAT
YVNVNIRDIDKIYVRTGIYHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARL
CLSICSVKGRKGAKEEHCPLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVT
GSNPNKETPCLELEFDHFSNPVKFPDMPAIEEHANWNISRELGFNYCHTGLSNRLARDNP
LTDSDNEQLRLVCNRDPLSEITEQEKDFLWRHRHYCVSIPEILPKILLAVKWNSRDEVAQ
MYCLLKDWPAIKPEQAMELLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYE
QYLDNPLARFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHL
SRQVEAMEKLINLTDLLKQEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLG
NLRLEECRMMSSAKRPLWLNWENPDMMSELLFQNLRQDMLTLQIIRIMENIWQNQGLDLR
MLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQ
AIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERV
PFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPE
LQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A2K5MGC2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cercocebus atys|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHLWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGYWVIYKGKSDEELSQYLLQLVQVLKYEPFLDCALS
RFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALN
KLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCK
YMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRML
PYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRA
IEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVP
FILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTS
VKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7F8QX47|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptonychotes weddellii|TrEMBL
MCFGFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECFKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
HPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVDCLRQMRFLLERALANRRIGQFLFWHLRSEVHIPAV
SVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMHTCLK
QNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNG
DDLRQDMLTLQMLRLMDLLWKEAGLDLR
>A0A7K6BD27|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Upupa epops|TrEMBL
MPPGIYCPMEFWSKGENQSIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWTAWMEYNFPLQLEPMAKGFGT
GPLHMPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATIFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGRTPHLTMVHSSTIIAMRDEQTNCIASPPKLA
AKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDHYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEEMGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C9Q2S8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Spermophilus dauricus|TrEMBL
MPLGIDWPMEFWTEVEKNRSVVVDFLLPTGIYLSFPVSRNANLSTIKQMLWHKAQNEPLF
HMLSDPKAYVFTCVNQTAEQQELEDEQQRLCDVRPFLPMLRLVTRQGDRMEKLINSQISL
LIGKGLHEFDCLQDPEVNDFRTKMCQFSEEAAAHRQQLGWEAWLQYSFPLQLEPSTRSWG
DSNTSQISNPDLLVNVKFEGSRESFTIQVSTKDVPLALMACALQKKAKVYQHLTMEQPED
YVLQVNGRHEYLYGSYLLCQFKYICSCLHSGQTPHLTMVHSSSILAMRDEQSRPAPQVQK
PHTKPPPIPMKKPSSVSLWSLGQPFCIELIQGSKINADEQMKLVVQAGLFHGNEMLCKTI
SSLEVSVCSEPMWKQHLEFDINICDLPRMARLCFALYAVMEKAKKAYSSKKKSKKEDCPI
AWANLMLFDYKDQLKTGELCLYMWPSVPGGPRPSRERLLEGEASRTGSPTTTSLLPSDEK
GDLVLNALELLDFSFPDCHVGSFAIRSLQKLTDDELFQCLLQLVQVLKYKSYLDCELTQF
LLDRALANRKIGHFLFWHLRYSEMHVPSVALRFGLIMEAYFRGSTHHMKVLMKQVEALSK
LKALSDFVKVSSQKTTKPQTKELMHLYMRQDTYLEALSHLQSPLDPSTMLAEVCVERCTF
MDSKMKPLWIMYSSEEAGSADSVGIIFKNGDDLRQDMLTLQMIQLMDALWKQEGLDLRWE
ALDRAIEEFTLSCARYCVATYVLGIGDRHSDNIMVRENGQLFHIDFGHFLGNFKTKFGIN
RERVPFILTHDFVHVIQQGKTSDNEKFERFRGYCEQAYSILQRHGLLFLQLFTLMQAAGL
PELSSSKDIQYLKDTLALGKTEEEGLKHFRVKFNEALRESWKTKVNWLAHNLTKDNRQ
>A0A803TGZ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anolis carolinensis|TrEMBL
MLPGIYCPVEFWSKEANQSIQVDFLLPTGIYLTLSVSCNATLGTIKQLVWHHAQCEPFFH
MLSDPESYVFTCINQTAERQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLISSQISLL
IGKGLHEFDSLGDLEVDDFRVKMQHFCEERAARRQQLSWKAWMEYSFPVQLEPLANGLGG
RSLLQFPNKNIFVNVKFESGGESFTFQISPKEYPATLMSYAIKKQATVFRHQKINSPEDY
ALQINGKYEYLYGNHPLYQFQYIRDCLCRGLLPHLTMVHASSISALWEEQTNGISYPIKA
ASKAPPVPKKKPMSVSLWSLEQPYSIELVQGSKVNADERMKLVVQAGLYHGHEMLCKMVS
SSEVSVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIA
WVNVMLFDFRDQLKTGECCLPMWSSFPDEKGELLNPMGTVQTNPNTESAASLVIRFPTIS
SNPLYYPTFEQILEQGKNGEWISLPFQMIYLLQSWPELPVLNALELLDFSFPDRYVGAFT
VNSLKKLTDADLFQYLLQLVQVLKYESYLDCELTKFLLGRALSNRKIGHFLFWHLSSQKN
AKPQTKEFMHTCMRQETYLEALSNLQSPLNPSVILAKVSVELCTFMDSKMKPLWIVFNNE
DAGGGHVGVIFKNGDDLRQDMLTLQMIQLMDILWKKEGLDLRMTPYGCLSTGDKTGLIEV
VMDSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALDRAIEEFTLSCAGYCVATY
VLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKT
NNSEKFERFREYCERAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKVRSLLPTA
RLSISFFFFFFYNNFY
>A0A6Q2ZE84|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPVEYGMLGEWEKEGDLEIMMDFLLPTGIFLKFSVSHNDTIGAIKKMVWSNASNEPLYG
ALSDMDAYVFTCINSTAEREELEDETRRLCDVRPFMPVLRLVAREGDRVEKLTNTQISLL
IGKGRNYYYYSLHKLMKIVNEFRAKMRSFCEERALERQQLPWYQWMEYSFPCELEPCVLL
AEPGGIKTKCKKIFVNVKFEASDESFMLQHEPQDLPVTLMRSALKKKATVFRSVHQEKPE
DYTLQVNGRWEFIYGKYPLCQFKYIFSCMRGGQTPHLTMVHHTTIVKYQEEQGRLASQVS
RCRSLSKPPPLPLKKNTSSLWSIEEPFNIHLIQGNRVNADEGMKLMVQAGLFHGSEMLCK
VVTSGEVNVCSEPLWDQKLVFDINVSDLPRMSRLCFALYAVIEKNKKPRSTKKKNKKADC
PLAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNIDSAPGLLIRFP
NIRPYPLYYPPLEKVRLSFPAHSQTLFSNWYLDNKNYTEFFEDDKELLWNLRGVVRQRYP
ESLSKLLLITKWNKREDVAQMVDLLHKWPELPALHALELLDYCFPDPRVRSFTIRCLRKL
SDEELLQYLLQLVQVLKYESYLDCDLTTFLLERALANKRIGHFLFWHLRSEMHVSSVSLR
FGLILEAYCRGNICHIKSLWKQNEALNKMKAVNDFVKSGWQKTSRQQMTDDMKLCIKQEA
YIWALSNLLSPLNPSIILSEICADRCKFMDSKMKPLWLMYKNKCVQGEAAGIIFKNGDDL
RQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSETIANIQRNNSNS
AATAAFNKDALLNWLKSKNPEDKLDNAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKET
GQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRAYCEQAY
KILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKVNWMMHSLAKDSRL
>A0A3B3UTY6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia latipinna|TrEMBL
MPPGKYGTQEEWEQDGDREIYMDFLLPTGIFLKFPVSRNDTIRNIKKMVWKNASREPLFF
GLGDPDLYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRSEKLTNAQISLL
IGKGLHEFEAQKNHEVDEFRTKMRTFCEEKSLERQNLPWQRWMEYSFPCELEPCSSPATG
GSSKSKHGKKLFVNIKFESSDESFMLQQDSQDLPVALMKSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGQHPLCQFKYIFFCMRNGQNPQLTMVHHSTISKYQEDQGRVCSQMYKTR
SLSRPPPLPLKKLVVQAGLFHGSELLCKMMTSSEVTVCSEPLWDQRLEFDINVSDLPRMS
RLCFALYAVIEKTKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGDFLLSMWPSVPDD
KSDLLNPMGTVQKNPNVDSAAGLLIRFPNIRPHPLYYPPLEKVYLKLKEIMDNKNYTEFF
EDEKELLWKLRIEVRDYFPECLSKLLLITKWNKREDVVQMVSLLKSWPELPAIQALELLD
YSFPDPAVRYFTIRCLKKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALTNRRIG
HFLFWHLKSEIHVASVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDIVKTGSQ
KMTVDDLKLCIRQESYLEALSDLLSPLNPSVILFEICADKCRFMDSKMKPLWLMYKNPLE
QADMVGIIFKNGDDLRQDMLTLQMIRLMENLWKKEGLDLRDKLDQAIEEFTLSCAGYCVA
TYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQG
RTNNSEKFERFREYCEKAYKILCRNGTLFVNLFAMMKAAGLPELSSSKDIQYLKDSLALG
KSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A3Q3J9D2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monopterus albus|TrEMBL
MDRQQIQISDEEPEVLCEQIRRRRRKKAITSSSSTSMDQITVEFVLPTATWGGNSPDTLQ
LEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIHYWRALKKDMGRIQLVPRSQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVSNGHILVVIHISTASQTIKVSID
DTPAQVLTSFFTKTANKRALLGKADYVLRVCGREEYLYGDKALQNFNWIRQCLKNDLEIH
LVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDENDHERVFTISMWDCNRKFRVK
VLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNIKIKDLP
KGARLNLQAYFCLFIHLLGKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEESS
SSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDVRASEMPNHLKKQFEA
IVATDPLHPLSPEDKELLWHFRHECMRNPRAYPKLLGSVKWGKQEDVLATHRLLERSSAW
DSSGLDVGLAMQLLDCHYSDTQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSAL
VRFLKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEAMLQDYRKQVDVTEALQQ
VTREIKAMSADKYDVTAQVVFQLRQKLETLQLSGLPESFRVPYDPGVRAGVLLIEQCKVM
ASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCL
LPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQA
VERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVP
FVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTS
KEDIEYIREALTVGRSEDDAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>G3W322|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sarcophilus harrisii|TrEMBL
MDLEDHDPVILREDNRGRRRKMKPQSAGMNLSSMEFIPIEFVLPTTHPLTKVAETVILEA
AGNCSVEQVKAQVWMQAVETSMTMEFYHQSSPEQFLLLYQKKEQWYEIYDKYQLIETLDC
VKYWKAFHKNMGQIHVVQRQPPTEETWAFQKQLNDLIDYDVTDMSNVHDDELEFTRRRLV
TPRIMEVASRDPKLYAMHPWITSKPLPTYLLKKIVNNCILIVIHRSTTSQTIKVSADDTP
GTILQSFFTKMAKKKSLMDIPESQNELDFVLRVCGRDEYIVGETPIKNFQWIRHCLKNGE
EIHLVLDTPPDPGQDEVRKEDWPLVDDCTGVTGYHEQLTINGKNHERVFTLSLWDCDRRF
RVKIRGIDIPVLPRNTELTVFVEANIQHGQQVLCQRRTTSKPFTEEVLWNVWLEFDIKIK
DLPKGALLNLQIYCGKAPSQSSKAAGSHEISSFEAKGKTQLLYYVNLLLIDHRYLLRHGE
YVLHMWKISGKGENQGSMNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPE
GDRVRGEMPNQLRKQLEEIIATDPLNPLTAKDKELLWHFRYESLKHPKAYPKLFSSVKWG
QQEIVAKTYQLLARREAWDQSDLDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHY
LLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEA
YLRGCGMAMLEDFTKQVQVIRLLQKVTIEIKSLSAEKYDVTSQVISQLKQKLENLQNSNL
PKSFRVPYDPGLRAGILMIEKCKVMASKKKPLWLEFKCADPTAQSNETIGIIFKHGDDLR
QDMLILQILRIMGSIWEAESLDLCLQPYGCISTGDKIGMIEIVKDAITIAKIQQSTVGNT
GAFKDEVLNHWLKEKCPIEEKFQAAVEKFVYSCAGYCVATFVLGIGDRHNDNIMITETGN
LFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQVTDSIWSYF
L
>A0A2R9CQ70|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan paniscus|TrEMBL
MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGIPGK
>A0A7J8HUJ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rousettus aegyptiacus|TrEMBL
MPPAMADILDIWAVDSQIASDGSILVDFLLPTGIYIQLEVPREATISSIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRIKMRKLSEEKIQSLVGLSWMDWLKQTYPPEHEPSILE
NLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDEVSPCDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINR
NSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCLAVYAVLDKVKTKKSTKTMNPSKYQ
TIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIVLHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLVELKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALA
NRRIGQFLFWHLRSEVHIPAVCIQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLI
KLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPL
WLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGD
RSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCA
GYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7J8D7K8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rousettus aegyptiacus|TrEMBL
MELENDEQLVVLREDNCRRRRRMKPRGPAASLSSMELVPIEFVLPTRQRTSKTPEIVLLH
VAGHGNVEQMKAQVWLRALETSVVADFYHRLGPDNFLLLYQKKGQWYEIYDKYQVVQTLD
CLCYWKVLHRSPGQIHVVQRHSPSEETLAFQRQLTALMGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLSKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPAQDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNSDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPVLSSKGPAEIPSSESKSKSQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGE
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQRVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGTLVVEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKSSLHFQKFQDICAKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEDDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7L3MJ82|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Horornis vulcanius|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHDSSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIPSD
TQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQ
>A0A8D0C5E8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salvator merianae|TrEMBL
MPPGIYCPVEFWSKEANRNIQVDFLLPTGIYLNLLVPCSATLSTIKKAVWHHAQYEPLFH
MLSDPDSYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSSGDPEVNDFRAKIHQFCAERAAQRQQLSWRAWMEYSFPVQLEPLAGSPER
KNSLRIPNKNIFVNVKFESGGESFTFHISPKELPMTLMSYAVKKQATVFRHQRINSPEDY
TLQVNGKCEYLYGNYPLYQFQYIHDCLHHGLLPHLTMVHSSSIMALWEEQANGIAHSPKS
VARPPPIPKKKVRGAFPLYLFPNILWLRQPSFWLASVRLDCLPTNSCPSFFQLVVQAGLY
HGNEMLCKMVSSSEVSVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTK
KKSKKADCPIAWVNVMLFDYKDQLKTGECSLPMWSSFPDEKGELLNPMGTVQTNPNTESA
AALVIHFPSVEAHLSFPVFRTFLLPVLLCTAQKQQLREILERRSHAELYEHEKDLLWKMR
YQIRDHYPGALAKLLVVTKWNKHEDVAQMVHLLQSWRELPVLNALELLDFNFPDRCVSSF
TVNSLKKLTDVELLQYLLQLVQVLKYESYLDCDLTKFLLDRALSNRKIGHFLFWHLRSEM
HVPSVAIKFGLILEAYCRGSPYHMKALMKQSEALSKMKALNDIVKLSSQKISKLQTKEYM
HACMRQETYMEALSNIQSPLNPHIILSKVSVELCTFMDSKMKPLWIVFSNKNMGGSNMGL
IFKNGDDLRQDMLTLQMIHLMDILWKKEGLDLRMTPYGCLSTGDKMGLIEAVMDSDTIAN
IQLNKSNMAATAAFNKDALLNWLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVVQQGKTNNSEKFERF
RDYCERAYMILRSHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEARKHFQ
LKFNEALRESWKTKVNWLAHNVSKDNSKPA
>A0A3B4UR34|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola dumerili|TrEMBL
EELDEEPKVLREDTRRRRRKKAITSSSGTSMDQITVEFVLPTVARGGSGPDSLLLEVAGN
WTVEQVKAQVWLKAVTSNLCPEFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDCIRY
WRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPR
RIELSDRDPKLYSMDPWVTRKLLPEHLLSKVSNSHILVVIHITTASQTIKVSIDDTPAQV
LASFFAKTANKRLLLGIPENMCEADYVLRVCGREEYLYGDKPLQNFNWIRQCLKNGEEIH
LVLEMPPDPDQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVK
VLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKIKDLP
KGARLNLQVVCGKQPLTPNSKGRKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKS
EESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVSRDAVAGGEEAEAGE
RGQREMPNHLKKQFGAIVATDPLHPLSPEDKELLWHFRQECMRDPRAYPKLLGSVRWGKQ
EDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLL
QLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYL
RGCGEAMLQDYRKQVEMTEALQKVTREVKAMSADKYDVTAQVVFQLRQKLETLQLSGLPE
SFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQD
MLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGA
FKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLF
HIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALR
HHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDDAQRHLLDQIEICREKGWM
VQINWFVHLVLGIKQGVEKRST
>A0A4W5P590|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
YLSSLFFYFYHYLTRQAQSYPLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFC
PMLKLVTRSCGRAERLLDSKIGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQL
MTWSEWLQACFSPQLEPGGGAPTTTDGVNNKQAEASLKVTMHFDQSQVTTVSLMEQALRK
WLTTHGPEEEGRQAEQYVLRVSDKLEFLCGDHPLIQYKSAEHCSLSQSPYYGEPLVVVVV
PPQVQVRAGLFHGTELLCKPAVSSESSGRSEHVWNRTLEFDITVSDLPRMARLCFAVYAV
MDKVKKQKSTKNHYPIAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPIGTIQTN
PYTENATALHIHLPDYNPHPILFPPFDKLLSISTTDMDVCDLLLQILEKGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTR
FLLNRAQCNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGIN
VEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGD
ALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A3Q0QWV5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amphilophus citrinellus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMETHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHEFDALNDQEVKDFRSKMFRISEEKMQEIQMMTFSEWVQACFSPQLEPV
AVTAITDGVXDAPADLKVIIHFDQSQDSASLKVSSSCTPNELMEQALKKWLTTHGSEEVV
WRSEYVLRVSHCLEFLSGDHPLIQYKYIRSCLQAKEPPHLTLVHTSTLRTMFDKDISVIG
AVVSRKSSNPPLPLPPKRRAPTVSWLANVNFNPSGHTQVQVRAGLFHGTELLCKPAVSSE
SSGRSEHTWRDNTLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKSTKSLHISKYQTIRKA
GKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATAL
HIHFPEYSSHSVVFPPFDKILEKAAEIVSADCVSIGRGVKKFYMELKEIMERDPVSQLCE
NEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDF
NYPDQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQKNRKIGH
FLFWHLRSEIHMPAVSVQFALILEAYCRGNIPHIEVLKKQVEALSKLKSVNELIKLGTIK
NTRSKTKEAMLTKEAMMTCLRQNYTTIYAFIEDCMRICFDRKYMDSKMKPLWIVYNNKLL
SGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRTGLIEVVS
SADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFTLSCAGYCVATYVL
GIGDRHSDNIMVRSNGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGN
TEKFGSFRQYCEDAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDE
EALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7L1BUW0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Illadopsis cleaveri|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWQQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPNKNIFVNIKFQSGGESFTFQISPWEFPITLMNYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITNPPKAV
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVAVCSEPVWRQRLDFDIGICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRATPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C2ZU55|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
RELDEEPKVLREDTRRRRRKKAISSSSGASMDQITVEFVLPTAARGGSGPDTLPLEVAGN
WTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDCIRY
WRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPR
RIELSDRDAKLYSMDPWVTRKPLPEHLLTKVSNAHVLMVIHIRTASQTIKVSIDDTPAQV
LVSFFAKTANKRVLLGIPDSMCEADFVLRVCGRFEYLYGDEPLQDFNWIRQCLKNGDEIH
LVLEMPPDTDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVK
VLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFSEEVLWNCWLEFNIKIKDLP
KGARLNLQVVCGKQPLTPNSKGTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEE
SSSSINADKLTSATNPDKASAMAVAILLDKYCYPVVLPKSRNAGNRDDGGRDREMPNHLK
KQFAAIVATDPLHPLSPEDKELLWHFRHECIRDPRAYPKLLGSVRWGRQEDVLATHRLLE
RSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPY
HDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDF
RKQVEMTEALQKVTREMKAMSADKCDITAQVVFQLRQKLETLQLSGLPESFRVPYDPGLR
AGALMIEQCKVMASKKKPLWLQFKRADPTTLSRDPIGIIFKDGDDLRQDMLILQILLIME
SIWETETLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFKDEILSQWLR
DKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNY
KSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTNLLIILFS
MMLMTGMPQLTSKEDIEYIREALTVGRSEDEAERHLLDQIEICREKGWMVQINWFVHLVL
GIKQGVEKRST
>A0A8C7TFY5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MEGHMFECVNQAAVHEELEDETRRLCDVRPFCPMLKLVTRNCGRAERLLDSKIGVLIGKG
LHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQACFSPQLEPGGGATPVTDGV
NDKQAEASLKVTMHFDQSQVTTVSRVVFTILYTLSCHQAGVTSTILYTLSCHQAGVTSTI
LYTLSCHQAGVTSTILYTLSCHQAGVRAGLFHGTELLCKPAVSSESSGRSEHVWNRTLEF
DITVSDLPRMARLCFAVYAVMDKVKKQKSTKNAHINKYQTIRKAGKVVCHTQSTDELEEM
LNPIGTIQTNPYTENSTALHIHLPDYNPHPILFPPFDKLDGRVKGKQPTSAQHFHIELKE
IMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPK
LSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFL
LNRAQCNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYSRGSIPHIEVLKKQVEALSKLK
SVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVE
KCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDL
RIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDAL
EKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRE
RVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPE
LTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A8C7SHH2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRTKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKQNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKV
VTSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCP
LAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFPN
IRPHPLYYPHFDKLRDLEKNGGKVIATKVEHMKLKEIVDNKNYTEFFEDEKELLWKLRGV
VRERYPESLSKLLLITKWNKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTI
RCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHV
SSVSLRFGLILEAYCRGNIYHIKSLCKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKL
CIKQEAYMEALSYLLSPLNPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDTVGIIF
KNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQ
RNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDN
IMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRE
CCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVK
FNEALRESWKTKVNWMMHSLAKDSRL
>A0A8C2ZAA4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHQ
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDSVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLDRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYLNGEASAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPCAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHY
SSSVKYPDMNAVEDHANWTISRELGYNYNLSGQSNRSARDHALTESDTEQMRQLSNRDAL
SEITEQEKDFLWRHRHYCMIVPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKGEIYSLFSKMYDLA
VDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVP
FVLTQDFLIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPEL
QSFDDIAYIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8C9V0I4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MEQEVCNDDQPVVFREENKRRRRKMKAFTSSVFKMTDLITVEFVLPTSPKTGKGFDSLQL
DVAGNCTVEQVKAQVWVKAIATNLCPEFYQKYSPDHCILLYQKKGNWYEIYDKHQVFQTL
DCICYWKTLKKEVGKIHLTIRPQLSEESIQYQKYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRKNELLTRDPKIYSMDPWITTKPLPEYLLSKISKNHILLVIHRNTSSHTVKVSIDD
TPNQVLQSFFTKIAKKRALLGIPEEVSESDFVLRVCGREEYIYGNYAIKDFHWIRQCLKN
GDEIHLVLETAPDPEQDVVHKEDWSQVDICTGLAATHEQLTIDEKDHEKVFTISLWDCNR
KFRVKILGIDIPTLPRNSELIVFVEASIFHGQQLLAQEKTCPKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTQPSKTAYPDSASHESKSKSRLLYYVNLLLVDHRSLLR
QGEYVLHMWKMPEKTEDLGSINADKLTSATNPDKGNSMAIAIMLDKYGYPVALPMSTEPS
ESSEGEDDERGHREMPSHLRKQLEQIVATDPLYPLSPEDKELLWHFRQECLRIPRAYPKF
LSSVKWGSQEAVLITHQLLARSSSWNQSPLDVGLAMQLLDCHFSDAMVRSLAVRKLEKLC
DDDVLRYLLQLVQAVKFEPYHDSALAQFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQR
YAVILEAYLRGCGDAMLQDFRKQVEITEALQKVTREIKAMSVEKYDVSVQVVFQLRQKLE
NLQTSGLPESFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFRRADPTTLSSDTIGIIF
KDGDDLRQDMLILQILLIMESIWEAESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQ
QSTVGNTGAFKDEILNQWLRENCPTDDKFEQAVERFVYSCAGYCVATFVLGIGDRHNDNI
MITESGSLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTTGKKSSPHFQKFQSP
VWGAL
>A0A8C9RIU5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MAPGVYCLPNMWEGGVQQVKMDFLLPTGIYLSFGVSGNDTIGAIKKTLWRNAKNEPLFFA
LSDPDAYVFTCINHTAEQEELEDEQRRLCDVRPMMPILRLVAREGDRVEKLITSQISLLI
GKGVHEFDTMKNHEVNEFRTKMRTFCEELAMDRQRLPWQKWIEYSFPCDLEPCALLSHSG
NLRNRASKKIIVNVKFEASDESFTLQVEPQEVPLTLMKSALKKKATVFRPMKQEKPEDYA
LQVNGRWEFIYGNFPLCQFKYIFNCLHSGVTPHLTMVHYSTITKYQEEQGGISREISKNR
SSSKPPPLPLKKQTMSSLWSIQDAFSIHLMHGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVNVCSEPVWDQKLEFDINVCDLPRMTRLCFALYAVIEKSKKPRSTKKKNKKADCPL
SWVNTMVFDYKDQLKTGEYYLSTWPSVPDDKTDLLNPMGTVEINPNTDSAAGLLIRFQNV
RPHPIYYPSLDKINDFMINGKKSVATKEEHLKVSEIVENKNYTEFFEDDKEILWKLRYEV
REKYSESLSKLLLITKWNKHEDVAQMVSLLQKWPDLPALHALELLDYSFPDRNVRSFTIR
CLRKLSDDELFQYLLQLVQVLKYESYLDCDLTKFLLERALSNKKIGHFLFWHLRSEMHVP
SVNLRFGLILEAYCRGSIYHMKTLMKQNEALNKMKSLNDFVKSASQKGTRTQTTGEMKKC
IKQETFMEALSDLLSPLNPSLILSEICPDRCKYMDSKMKPLWLVYKNEKVQGDPLGIIFK
NGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQR
NNSNSAATAAFNKDALLNWLKSKNPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRENGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREY
CEQAYKILCRNGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKF
NEALRESWKTKVNWMVHSVSKDNR
>A0A8C9T1V1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MAPGVYCLPNMWEGGVQQVKMDFLLPTGIYLSFGVSGNDTIGAIKKTLWRNAKNEPLFFA
LSDPDAYVFTCINHTAEQEELEDEQRRLCDVRPMMPILRLVAREGDRVEKLITSQISLLI
GKGLFIHEFDTMKNHEVNEFRTKMRTFCEELAMDRQRLPWQKWIEYSFPCDLEPCALLSH
SGNLRNRASKKIIVNVKFEASDESFTLQVEPQEVPLTLMKSALKKKATVFRPMKQEKPED
YALQVNGRWEFIYGNFPLCQFKYIFNCLHSGVTPHLTMVHYSTITKYQEEQGGISREISK
NRSSSKPPPLPLKKTLVVIIRNMRFVPQLVVQAGLFHGSELLCKVVTSSEVNVCSEPVWD
QKLEFDINVCDLPRMTRLCFALYAVIEKSKKPRSTKKKNKKADCPLSWVNTMVFDYKDQL
KTGEYYLSTWPSTDLLNPMGTVEINPNTDSAAGLLIRFQNVRPHPIYYPSLDKVTIATFY
KMCRNTDSQFWRSYEKHIKILLRLSTLHLLLSEILWKLRYEVREKYSESLSKLLLITKWN
KHEDVAQMVSLLQKWPDLPALHALELLDYSFPDRNVRSFTIRCLRKLSDDELFQYLLQLV
QVLKYESYLDCDLTKFLLERALSNKKIGHFLFWHLRSEMHVPSVNLRFGLILEAYCRGSI
YHMKTLMKQNEALNKMKSLNDFVKSASQKGTRTQTTGEMKKCIKQETFMEALSDLLSPLN
PSLILSEICPDRCKYMDSKMKPLWLVYKNEKVQGDPLGIIFKNGDDLRQDMLTLQMIQLM
EILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLN
WLKDKLEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKSK
FGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYKILCRNGTLFVNLFALMR
AAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMVHSVSKDN
R
>A0A7K7XMC0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mohoua ochrocephala|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVTAWYQLLGGRSY
EPLFHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINS
QISLLIGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMA
KGLGTGSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIRKQATVFRHETLQK
PEDYTLQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIAS
PPKAASKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLC
KTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAD
CPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICF
PSVAAHPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVW
KMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYV
GSFAINSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLR
SEMHVPAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTK
EMMHMCMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGG
VGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDT
IANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGD
RHSDNIMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKF
ERFRGYCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALK
HFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A087XH12|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia formosa|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDSVPEQVIAEAIRKKTRSMLLTQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMSKESLYSQLPME
NFTMPSYARRISTATPYMNGETATKCLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYVTEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMSMIEDHANWNISRELGFNYSHPGLSNRLARDKPLTESDNEQLRQVCNRDPL
SEITEQEKDFLWSHRHYCINIPDILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHALHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8C2TJ21|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coturnix japonica|TrEMBL
MALCFSVSRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGAIKQVVWK
HAQYEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKK
LINSQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQL
EPMAKGLGTGLSHTPVKNIFVNVKFQSGGVNFTFQISPNEFPITLMSYAVKKQATVFRHE
TMENPEDYTLQVNGKYEYLYGNYPLYQFQVSLLSCFDKRVCPPCTHFSGRVVDGSADEMS
SARQVTFLAMPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNAAS
HPVYYPSFEQVGNTDVFLRGFLLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQAL
AKLLTITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDH
ELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGL
ILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQETYLE
ALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQD
MLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAAT
AAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQL
FHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYMIL
RRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESW
KTKVNWLAHNVSKDNRQ
>A0A6P3RLI9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pteropus vampyrus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQITSDGSILVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKLSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIILVKGSKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCLAVYAVLDKVKTKKSTKTM
NASKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIVLHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALYIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLVELKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVECLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVCIQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A401PU59|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scyliorhinus torazame|TrEMBL
MRANTSRNMQYYSLEQLAIEFVLPTRNKFNNDHEKVSLEVAGNYTVEQLKAKVWVKAGGI
SACPDFYRKLSPDQFRLMYQKKGQLYEIYDKHQVIQTLDCINYWKALQKSNGKIHLVQKT
KASKESLQLQNDLNYLIGYDVTDVSNVHDDELEFTRRKLITPQLNEVSTRDARLYSMDPW
IISKPLPEYLLSKICNNNIFIIIHRGTTSLTIKVSIDETPQSILKNFFKKMANKKGLLDI
AESHNEEDFVLRVCGREDYIVGDNPIKDFHWVRSCLKNGEEIHFVLDLPPDPALDEVQKE
EWPLVDDCTGVTGSHEQLTLEGRDHDKVFTISLWDCNRKFRVKIIGIDIPVLPKNTELTV
FVEASILHGQQVLAQQRTPTKAFTEEVLWNVWLEFDIKVKDLPRGARLNLQVYCGKALAQ
GARGAFQSQDDNMWDIKSKNHMLYYVNLLVINHRSLLRQGEYVLHMWKIPDKGEEQGTIE
ADKLTSATNPDKQTSMAICILLDRYNYPIALPQSCHDPEIERSGHEMHSQLRKQFEEIIS
TDPLNPLSVEDKELLWHFKHECLRQPKAYPKFLSSVKWGQQEVVLKTHQLLDRQDVWDRS
PLDVGLAMQLLDCRFSDEQVRALAIRKLETLDNSEVLRYLLQLVQSKRTGHFLFWFLRSE
VAESMHHRQRYAVILEAYLRGCGTAMLMDFMRQVKVMEALHKVTLEIKNVTAEKYDVSAQ
AISQLRHKLEKLQSTGFPECFRVPYDPGLRAGVLVVDKCKVMPSKKKPLWLEFKCADLTS
ISKDTIGIIFKHGDDLRQDMLIIQILLIMDSIWETESLDLCLLPYGCIATGNKIGMIQIV
KDATTIAKIQQSTVGNTGAFKDEVLNHWLKDKCPIEDKFQSAVERFVYSCAGYCVATYIL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKT
SRHFQKFQDICVKAYLALRHHTNLLIILFSMMVMTGMPQLTSKEDIEYIRETLTVGKNEE
EAKKHFLDQIEICRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8B9VF33|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas zonorhyncha|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GLLHTPTKNIFVNVKFQSGGESFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANTPKMS
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPNVAS
HPVYYPSFEQLLELGRNGEPPRTMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSL
KKLTDNELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAV
ALRFGLILEAYCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCMK
QETYLEALSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNK
SNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCE
KAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKVRKAEPGYS
>A0A670YIE1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pseudonaja textilis|TrEMBL
MPPGMYCPSEFWSKESNYTIHVDFLLPTGIYLPLPVSCHASLAAIKKVVWHQAQYEPFFQ
MLSAPDSYVFTCINQAAELQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLLNSQISLL
IGKGLHEFDSLADPEVNDFRVQMQDYCEQKAAQRQQLSWKDWMEYSFPVQLEPALSGLGR
RPSLPMPGKTIFVNVKFQSGGESFTFQISLKEFPITLMSYAVKKQATIFRHQRVSPADEY
TLQVNGKYEYIYGEYPLYQFQYIRECLHRRFVPHLIMVHRSSLLTLREEQSNGLGHPPKT
ALKLSPGPKQKLTCVSLWSLDQPYYIELLHCSKVNADEGMKLVVQAGLYHGHEMLCKMMT
STEANVCSEPTWDQTLKFDIHVCDLPRMARLCLVLYSVVEKAKKARSTKKKSKKADCPLA
WVNVMLFDYQDQLKAGECVLPMWSAFPDEKGELLNPTGTIQTNPNAESAATLFIRFPGIS
LYPIYYPSMRQILEKGQNGHCACGTGEDPEEQLKEILERRSCIELYEHEKDLVWKMRYQI
RDQYPGALAKLLMVTKWNKHEDVAQMIFLLQSWPELPVLNALELLDFNFPDPHVSRFTVN
SLKKLTDAELFQYLLQLVQVLKYQSYLDCELTKFLLGRALSNRKIGHFLFWHLRSEMHFP
SLALRFGLILEAYCRGNADHIKALMKQSEALNKLKALNDLIKVSAQKNTKPQTKEFMHTC
MRQETYLEALSHLQSPLDPRIFLARVSVELCTVMDSKMKPLWIMFNNGEAGGPNTGLIFK
NGDDLRQDMLTLQMIQLMDILWKQEGLDLSDALEQAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMVRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFER
FRDYCERAYMILRGHGLLFLHLFSLMKAAGLPELSCSKDIQYLKDSLALGKTDEEARKQF
HLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C3LMM2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysolophus pictus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINSIANPPKMA
VKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALLICFPNVAS
HPVYYPSFEQLLELGRNGEQPRSMISLLQSWPELPVLNALELLDFSFPDRYVGSFAINSL
KKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMK
QETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLACAGYCVATYVLGIGDRHSDNIMI
RETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
KAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKVRKAEPRCG
>A0A673AVH2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
VYPLLWKQAQSFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTR
NCGRAERLLDSKIGVLIGKGLHELDAINDQEVKDFRSKMFRMSEERMQRVQMMTWMEWLQ
ACFSPQLETSGGATITDGVAERPADLKVIIHFDQSQVRVLHPMAVKKWLTTHGPEEEAWR
GQYVLRVSHCLEFLCGDHPLILYKQVQTCVWDVSSLFKIVLVSGSKVNAEETAKVQVRAG
LFHGTELLCKPAVSSESSGRSDHTWKDSTLEFDIAVCDLPRMTRLCFAIYAVMDKVKKQK
STKNTHLNKYQTIPWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYT
ENATALHIHFPEYSSHPIIFPPFDKVRQHDDLMNTETAGRNSGPLLLSFFYLSQGRGGKK
FHIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQA
LLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLSDMSDEELSQYLLQLVQVLRYEPYYD
CALTHFLLQRAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQV
EALSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNIL
LSGINVEKCRYMDSKMKPLWIVYNNKLLGGDTRGIIFKNGDDLRQDMLTLQILRLMDLLW
KEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKE
RNSGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKS
KFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGTLFITLFALM
LTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKD
NRS
>A0A672ZWP8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
MPPGKYGMQEEWEKEGDQGIMMDFLLPTGIFLKFLVSRNDTIKSIKKMVWKNARSEALFA
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRMFCEEKALDRQRLPWQQWMEYSFPCDLEPCCSPPEC
GNAKSKNTKKLFINVKFEASDESFMLQQDPQDLPVALIRSALKKKATVFRSVRQEPEDYT
LQVNGRWDFIYGSHPLCQYKYIFFCLRNGQNPHLTMVHHSTISKYQEEQGQMCNQVFKSR
SLSRPPPLPLKKNTSSLWSINEPFYIQLLQGNRVNADEGMKLVVQAGLFHGSELLCKVVT
SSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIR
QHPLYYPPLEKVLDPKHFCTGITSLKEIMDNKNYTEFFEDEKELLWKLRSVVRDHYPESL
SKLLLITKWNKREDVVQMVGLLRNWPELPAIHALELLDYSFPDPAVRSFTIRCLRKLSDG
ELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVSCVFGL
ILEAYCRGNIHHIKLLTNRYLPTLSKSGSQKMTAEDLKLCIRQESYVEALSDLLADKCRF
MDSKMKPLWMMYRNPFVQGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEAIEEFTLS
CAGYCVATYILGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDF
VHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYL
KDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A672ZYY5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
MPPGKYGMQEEWEKEGDQGIMMDFLLPTGIFLKFLVSRNDTIKSIKKMVWKNARSEALFA
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRMFCEEKALDRQRLPWQQWMEYSFPCDLEPCCSPPEC
GNAKSKNTKKLFINVKFEASDESFMLQQDPQDLPVALIRSALKKKATVFRSVRQEPEDYT
LQVNGRWDFIYGSHPLCQYKVSDLLNGQNPHLTMVHHSTISKYQEEQGQMCNQVFKSRSL
SRPPPLPLKKNTSSLWSINEPFYIQLLQGNRVNADEGMKLVVQAGLFHGSELLCKVVTSS
EVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWV
NTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRQH
PLYYPPLEKVLDPKHFCTGITSVICQLKEIMDNKNYTEFFEDEKELLWKLRSVVRDHYPE
SLSKLLLITKWNKREDVVQMVGLLRNWPELPAIHALELLDYSFPDPAVRSFTIRCLRKLS
DGELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVSCVF
GLILEAYCRGNIHHIKLLTNRYLRTNALGKMKKMTAEDLKLCIRQESYVEALSDLLARRS
TEQIIFFVKLFMDSKMKPLWMMYRNPFVQGDMVGIIFKNGDDLRQDMLTLQMIQLMENLW
KKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDEKLEKAIE
EFTLSCAGYCVATYILGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFI
LTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFK
DIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A8B9VF23|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas zonorhyncha|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GLLHTPTKNIFVNVKFQSGGESFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANTPKMS
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPNVAS
HPVYYPSFEQLLELGRNGEPPRTQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYP
QALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKL
TDNELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALR
FGLILEAYCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCMKQET
YLEALSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIFKNGDDL
RQDMLTLQMIQLMDVLWKQEGLDLSDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
EKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7N6A7G5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MDRKQIQVSDEEPVVLREEIRRRRRKKAITSSSSISMDQITVEFVLPTATWGSNPDSLQL
EVAGNWTVEQVKAQVWLKAVTSNLCPEFYQRFSPDHCILLYQKKGNLCEIYDKHQVFQTL
DCIRYWRALKKDVGKIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRRIELCDRDPKLYSMDPWVTRKPLPEHLLSKVSNGHILVVIHMSTASHTIKVSIDD
TPAQVLASFFNKTANKRVLLGIPDNVCETDYVLRVCGRYEYLYGDKPLQNFNWIRQCLKN
GEEIHLVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNR
KFRVKVLGIDIPTLPKVPEFVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIK
IKDLPKGARLSLQCCDVTTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEESSSS
INADKLTSATNPDKESSMAIAILLDKYCYPVVLPKSRDVGRDVGAVGEESEGGERGQREM
PNHLKKQFEAIVTTDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVKWGKQEDVLAT
HRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAV
KFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEA
MLQDFRKQVSNNHLLALQKVTREIKTMSADKYDVTAQVVFQLRQKLEILQSSGLPDNFRV
PYDPGLRAGALMIEQCKVMASKKKPLWLQFKKADPTTLSKDPIGIIFKDGDDLRQDMLIL
QILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFKDE
ILYQWLRDKCVSEEKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDF
GHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTN
LLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQIN
WFVHLVLGIKQGVEKRST
>A0A8C3KAI7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calidris pygmaea|TrEMBL
SQEVSRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQ
YEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVIN
SQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPM
TKGLGAGPLHTPTKNIFVNVNFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYTL
QVNGKCEYLYGNYPLYQFQVSFLSCFVNESVPVCPPPPRGPNYGSLWSLEQPFYIELVQG
SKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARL
CFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKG
ELLNPMGTVQCNPNTESAAALVICFPSVASHPVYYPSFDPVYALSCDSHEQKLQLKEILE
RRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQSWPELPV
LNALELLDFSFPDRYVVLPTRDMQIKIRLSFIFPFGPHRDNELFQYLLQLVQVLKYESYL
DCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQ
GEALNKMKALNDFVKASSQKATKPQTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVC
VDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGL
DLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGD
ALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGIN
RERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGL
PELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A091VBJ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Opisthocomus hoazin|TrEMBL
STMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLNWAAWMEYNFPLQLEPLAKGL
GTGPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSMIIAMRDEQTNCIASPPK
MVAKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQSLSGLRKSLGLRLSPVCALSCDSHEQKLQLKEILERRSHTELYEHEKD
LVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMIFLLQTWPELPVLNALELLDFSFPD
CYVGFFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFW
HLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKSLNDFVKASSQKATKP
QTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETG
GDGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMH
SDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLG
IGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNN
EKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDDE
ALKHFRLKFNEALRESWKTKVNWLAHNVSKDNR
>G3NWI2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gasterosteus aculeatus|TrEMBL
MPPGKYGMQEEWEKEWDQQIGMEFLLPTGIYLKFPVSPNDTIKSIKKMVWKNASSEALFS
ALGDPEAYVFTCINQTAEREELEEESRRIRDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRAKMRAFCEETAQERQMLPWQQWMEYSFPCELEPCCSPCGF
GRVKSKNKKKIFINVKFDACDESFMVQQDPQDLPVALMRSALKKKAAVFPTLRQEPQDYT
LQVNGRWEFIYGKHPMCQFKYIFSCLRNGENPYLTMVHHSAIHKYQEEQGRMCSQLYKSR
SLSRPPPLPLKKQNTSSLWSIREPFYIHLLQGSRVNAGEGMKLVVQAGLFHGSELLCKVM
TTSEVSVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPADKSDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPPLDKLSGDMEKNGDATVATKEEYLKLKEIMDNKNSTEFFEDEKELLWKLRTE
VRDRFHESLSKLLLVTKWNRHEDVVQMVSLLRNWPDLPAIHALELLDYSFPDPAVRSFTI
ACLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLRSEIHV
ASVSLRFGLILEAYCRGNIHHIRLLTKQNEALGKMKALSDFVKSGSQKMTADDLKLCIRQ
ESYLEALSDLLSPLNPSISLADICADKCRFMNSKMKPLWLMYNSGAQGDTVGIIFKNGDE
DLRQDMLTLQMIQLMENLWKREGLDLRMLPYGCLSTGNKMGLIEVVKNSDTIANIQRNSS
NSAATAAFNKDALLNWLKSKNPEDKLDPAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIR
ETGQLFHIDFGHILGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCER
AYKILCRNAMLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEA
LRESWKTKVNWMMHSLAKDNR
>A0A7N8X9V0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MTPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFAEARKYPLHH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRTILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
ISSKLDKGSLPVRRQSWSQDSSDKQNLICVSHDSLPEQLIAESIRKKSRSMHLSPQQLHL
CVQEYQGQYILKVHLTTCLTHYLSVHLSQYIRSCIIMGRLPHLMLVSKDSLYSQLPASGF
VTPSYSRRTPQPSPCPGGGDGPPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFSWF
NQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAADVEQLRSVCSKDPLY
ELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESALEL
LDCNFPDPMVREFALRCLVQGLSDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQ
RIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQ
EKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWL
NWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSI
GDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIRDKNRGEAYDRAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQTFDDIAY
LRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPSDH
>A0A7N9B193|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MTPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFAEARKYPLHH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRTILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
ISSKLDKGRLIVSIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLH
LCVQEYQGQYILKRSDRGTAHRSKLYARKKKITSRTKIHHVCD
>A0A2D0SH09|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ictalurus punctatus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDSEVQDFRRSILSVCREAMEEREGGGPHTHALYVYPPSVESSPQLPQH
IYAKLDKGRLIVTIWVVVSPSNAKQKYTLKIAHDCMPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGKLPHLMLVSKDSVYDQLPCS
GFVTPSYSRRTPQPSPSPGGGDPANPRSLWTFNAHTPLRIRLICATYVNVNIRDIDKIYV
RTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLMYDISLTDLPRSARLCLSICSVKGRKGAK
EVSPLTFASIEWSLETPCVELEFPSFNHTVVFPDEQQIEEHANWIISRELGYNYSLGLSN
RLVCDSSISQAEAEQLRALCNRDPLYELSEQEKDFLWRHRHYCVNIPESLPKLLLAVKWN
SRDEVSQMYCLLRDWPLMQPESALELLDCNFPDPMVREFALRCLMQGLTDDKISQYLLQL
VQVLKYEMYLDNPLARFLVKKALTNQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRSC
GIYLKHLNRQVEAMDKLVNMTDTLKHEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPL
NPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQ
IIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSFTIMQIQCKGGLKGALQFNSN
TLHHWIREKNKGETYDSAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFG
HFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHA
GLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKM
DWIFHTIRHMPNEH
>A0A3Q2UY85|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Haplochromis burtoni|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDSEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8D0LX84|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MCFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDYPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPDVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRXXXXMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSK
MKPLWLVYNNKVFGEDSIGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCL
ATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFT
LSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTY
DFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQ
YLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6P8NQM6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MPPGVYFPADFWAKEQNKNILIDFLLPTGIYITFSVPRNASLGNIKQSLWHHAQYEPFYH
MLSEPQAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVQKLINSHISLL
IGKGLHDFDSVGDLEVRDFRSKMRQFCEEKAAERQQLGWEAWMEYSFPLQLEPSARLLKM
GIFHINSKNIIVNIKFESSEESFTLQISAKEFPLALVRSALKKKAIVFRQQNKEEPEDYT
LKVNGCSDYIYGQYPLCQFKYISGCLYHNLTPHLTLVPTKSIKELRDEQENLSLQVSKLR
SKPPPPPLPVKKLSPVSLWNFEQAFCVKILQGSNVNADECLKLVVHAGLFHGNEMLCKAV
RTAEVSESSEPIWNQMMEFDIGICDLPRMSRLSFILYAVEKTKKARSTKKKSKKAILELG
KAGEQQCSTVDEQQQLKELLERRGSVELYEHEKDMLWKLRHEIREQYSEALARLLLITKW
NRHEDVAQMLYLLQSWPELPVLFALELLDYNFPDRCVRAFTVNCLKKLSDEELCRYLLQL
VQVLKYESYLDCELTTFLLERALANRKIGHYFFWHLRSEIHVPAVALRFGLLLEAYCRGS
HYHMKVLVKQVEALTKMKALNDIVKISSQKATKPQTKEVMHVCLKQENYLEALLNLQSPL
NPSVILGNVCVDLCTFMDSKMKPLWIMYNNEMNQNHVGIIFKNGDDLRQDMLTLQMIHLM
DILWKQEGLDLRMTPYGCLSTGDKTGLIEIVGNSDTIANIQLNKSNMVATAAFNKDALLN
WLKSKNPGVALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLG
NFKTKFGINRERVPFILTYDFVHVIQQGKPNNNEKFERFRNYCEKAYMVLRLHGPLFLHL
FALMKAAGLPELSCSKDIQYLKVKQCSG
>A0A8B9XN24|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus grunniens|TrEMBL
MGTANPQPGWLCCRIAVLWMVLAGSGKDDWYLRSEKAGCPPGLTAPWNSGPRRRIRAWQL
ISCSPRGLSELPVSRNANLSTIKKVLWHRAQYEPLFHMLSDPEAYVFTCVNQTAEQQELE
DEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHEFDSLQDPEVNDFRGKM
RQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGPGTLRVPNRVLLVNVKFEGSEESF
TFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYTLQVNGKHEYLYGSYPLCQFQYIC
SCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRTKPPPIPMKKPSSVSLWSLEQPF
YIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSVCSEPVWKQRLEFDINICD
LPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGEHCLYMWP
SVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAPHPVYYPSLDKILELGRLGEHGRF
TEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQEHFPEALARLLLVTKWNKHEDVAQ
MLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYES
YLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLM
KQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDPSTLLAE
VCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKNGDDLRQDMLTLQMIQLMDILWKQ
EGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKN
PGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGISRPSL
ESTVAGPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAA
GLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A091LN72|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cariama cristata|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A850VN40|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fregata magnificens|TrEMBL
MELEDYEQPVVMREENKRRRRRMKPHCMSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIVGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNVWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQPHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAVSIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQRS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEK
>A0A8B9MGM2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Accipiter nisus|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSVSVDFLLPTGIYIKLDVPRDATISHIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWRDWLKHTYPPEQEPVIPE
SFQDKLYSGNIVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAE
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHIWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIKFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNN
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQCCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEDEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8I3S601|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MEPQGCEPRVVLREDHRRRRRRMKARGPAAGLPSMELIPIEFVLPTSQRSSKAPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYQRLGPDHFVLLYQKKGQWYEIYDRYQVVQTLD
CLRYWQLLHRSPGQIHVVQRRAPSAATLAFQRQLTALIGYDVTDLSNVHDNELEFTRRRL
VTPRMLEVAGRDPELYAMHPWVTSKPLPDYLRKRIPNNCVFIVIHRGTTSQTVKVSADDT
PGAILRSFFAKMAKKKALMGIPEGQSERDFVLRVCGRDEYLVGDTPLQNFQWVRQCLKNG
EEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRR
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFSIKI
KDLPRGALLNLQVYCSKAPTLSAKASADAPGAGSEARGKAQLLYYVNLLLIDHRFLLRRG
EYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDP
EGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKW
GQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLH
YLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLE
AYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLN
LPESFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDL
RQDMLILQILRIMESIWETESLDLYLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGN
TGAFKDEVLNHWLKEKCAIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETG
NLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYL
ALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDK
GWTVQFNWFLHLVLGIKQGEKHSA
>A0A8I3PUD5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNDFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPNDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKNI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSLQALLQIWPKLPP
REALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLER
ALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLN
SLIKLNAVKLNKAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKM
KPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLA
TGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTL
SCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYD
FIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A091GJF2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cuculus canorus|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSVSVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDESRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIHSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYGGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGREDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLIECCTIKKMCEQEMIAVEA
AINRKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKSGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPVNYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A852LMK1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Centropus bengalensis|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQNEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLGWAAWMEYSFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHQGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKRPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTDSAAALVICFPSVTS
HPVYYPSFEQLLELGRNGEQPRAVPEDPEEKLQLKEILDRRSYTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELLQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKSLNDFVKSSSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGRAGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A5A9MWN7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Triplophysa tibetana|TrEMBL
MFVGKYMIKSQVTVIVCVGKSGYCHGGIEICISTQQRHLYRFGTTRRFPWFGSSVLFAMP
PAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYPFF
SLLGEMEGHMFECVNQAAVHEELEDESRRLCDVRPFLPVFKLITRNCGRAERLLDSKIGV
LIGKGLHELDALQDQEVKDFRTKMKRISEEKMQRVQMMPWGEWLQSCYSPQLETGPDNMI
DKHEGGIKITMHYEQSQDTASLKVSLNCTVSELMDQALKKWQTTHGPEEDIGARSDYVLR
VSAKLEFLFDDHPLNQCKYIRDCLLANESPHLTMVHVNFVKAMFDKEISTIGSALARKLS
NPPLPLPPKRRTPTQLHTCVWKVNSLFRINLVKGIKVNAEDNAKIQVRAGLFHGAELLCK
PAVSSESGSRSEHMWNKTLEFEIPVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHQNKYQ
TIRKAGKVHYPIAWVNTMVFDYRGHLKTGDIVLHCWSSFPDELEEMLNPIGTIQTNPYTE
NATELHISFPQYSTQPVVFPPFDKGRAGKKFFIELKEIMARDPLSQLCENEKDLIWTLRH
DCRETLPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSSRDALELLDFNYPDQYVREFA
VNCLRDMRSEMHISSVSVHFALILEAYCRGTIPHIEVLKKQVEALSKLKTVNELIKLGTI
KTKNKSKEAHLKEAMMTCLRQTGFIETLSDLQSPLDPSVLLAGVSVEKCRYMDSKMKPLW
IVYNNKLLDGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDQ
SGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALEKAVEEFTLSCAG
YCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHV
IQQGKTSNTEKFGNFRQYCEEAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKDS
LALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAHPS
>A0A6I9HPR3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geospiza fortis|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVNEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPTKNIFVNIRFQSGGESFMFQISPREFPITLMSYAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPNYGSLWSLEQPFYVELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>W5LYU4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lepisosteus oculatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLVTIKHELFKEARKYPLHH
LLQDETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVDLRDANGPHSRALYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKESLYSQLPID
NFTMPSYARRISTATPYMNGEASTKSLWSINSNLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDFF
SSPVKFPDMATVEDHANWTVSRELGFNYCHTGLSNRLARDNALTESDTEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDLAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A3B3QEZ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Paramormyrops kingsleyae|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILNVCREAMEEREGGGAHSQALYVYPPNVESSPDLPQH
IFSKLDKGRLIVTIWVIVSPSNAKQKYTLKIAHDALPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDSSAPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLTDLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYRNTLVSGKVALSLWPMPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVIFPDEQQIEEHANWTISRELGYNYSMGLSSRLACDNTMSQGDVEQLLSLCSRDP
LYELSEQEKDFLWRHRHYCVNIAESLPKLLLSVKWNSRDEVSQMYCLLRDWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMEKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A8C4HS74|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MDVPREATIQHIKLLLWKQAQSFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVR
PFLPVLKLVTRNCGRAERLLDSKIGVLISKGLHELDGINDQEVKDFRSKMFRMSEERMQK
VQMMTCMEWLEACFSPQLEPAPGTAITDGLNDRPADLKVTIHFDQSQVRVCSPVTPIDLM
ELALRKWLTTHGPEEEAWRGQYVLRVSHCLEFLCGDHPLIQYKVSAWKQISKLTKLNIRY
HILASPLHATSSLHSTQVQVRAGLFHGTELLCKPAVSSESSGRSDHTWKDSTLEFDISVS
DLPRMTRLCFAIYAVMDKVKKQKSTKNHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPD
ELEEMLNPIGTIQTNPYTENATALHIHFPEYSSHPIIFPPFDKVRQLSVIVLSVPYSPYS
RGGKKFHIELKEIMERDALSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDM
AQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMRLTYELSQYLLQLVQVLR
YEPYYDCALTHFLLERAQRNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIE
VLKKQVEALSKLKSVNELIKLGTIKNARKAKEAMLTKEAMMTCLRQSGYSETLSDLHSPL
NPNVLLSGINVEKCRYMDSKMKPLWIVYNNKLMGGDTLGIIFKNGDDLRQDMLTLQILRL
MDLLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALL
NWLKERNTGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHIL
GNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFIT
LFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAH
NVAKDNRS
>A0A2I4CKD2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Austrofundulus limnaeus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILILECLREATLNTIKHDLFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKHPISQYKYIRSCIMLSRLPNLMLMAKDSLYTQLPID
NFVMPSYSRRISTATSYMNGEASSKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPEMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTETDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKKTDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEAVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLXSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A7K9CX78|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hemiprocne comata|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELIPIEFILPTSNKHTKVPEMMLLE
IAGNYTVEQMKAQVWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GDYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIVQLRQKLEKLQSS
KLPGSFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A2I4CTJ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Austrofundulus limnaeus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMLKDPEVQDFRRSILGVCREAVEEREGGGAHSQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDTLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
SFVAPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVLFPDEQQIEEHANWTISRELGYNYCHGLSNRLACDNSVSAADAEQLRSICSKDP
LYELSEQEKDFLWRHRHYCINMPESLPKLLLSVKWNSRDEVSQMYCLLREWPLMEPELAL
ELLDCNFPDPMVREFALRCLVQSLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNNTVCRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMDSLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A7L4JR97|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ceuthmochares aereus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPETLLLE
IAGNCTVEQMKAQIWMRAIEMSQVTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQPPSEVVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGVSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSILDVGLTMQLLDCNFSDENVRAMAVQKLESLDDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSASAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A667WCE0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MPPGKYGMQAEWEKEGDHKIMMDFLLPTGIFLKFPVSRNETIKNIKKMVWRNAATEPLFS
ALGDSDAYVFTCINQTAEREELEDESRRISDVLPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHDFEAQKNHEVNEFRSKMRSFCEEKALERQLLPWHQWIEYSFPCELEPCSSLPES
GNTKSKNTKKIFVNIKFEASDESFMLQQDPHDFPVSLMKNALKKKATVFRLVRQEPEDYT
LQVNGRWDFIYGKHPLCQFKYIFSCLRNSQNPHLIMVHSSTINKYQEEQGTMCSQVSKSG
SLSRPPPLPLKKNTSSLWSINEPFYIHLVQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SSEVAVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIR
PHPLYYPPHDKVLNPKHLYLSLKEIMDNKNYTEFFEDEKELLWKLRAEVRDRYPESLSKL
LLITKWNKREDVAQMLSLLRNWPDLPALHALELLDYSFPDPTVRAFTIRCLRKLSDDELL
QYLIQLVQVLKYESYLDCDLTTFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILE
AYCRGNIYHIKVLSKQNEALGKMRALSDFVKTGSQKMTAEDLKLCIRQESYLEALSDLLS
PLNPSIILSEICADKCRFMDSKMKPLWLMYKNQWVQGDMVGIIFKNGDDLRQDMLTLQMI
QLMENLWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDA
LLNWLKSKNPEDKIDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGH
ILGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCERAYKILCRNGTLF
VNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFTEALRESWKTKVNWM
MHSLAKDNRP
>A0A673X0P1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPAMTNLMDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQQVQLMTWSEWLQACFSPQLEPGGG
ATPVTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQVLSYHQTIVLIKGSKVNAEETAKVQVRAGLFHGT
ELLCKPAVSSESSGRSEHVWNSTLEFDITVSDLPRMTRLCFAVYAVMDKVKKQKSTKNAH
INKYQTIRKSGKVHYPVAWVNTMLFDYKGQLKTGDIILHSWSSFPDELEEMLNPIGTIQT
NPYTENTTALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCLPMGRGGKKFHIELKEI
MERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKL
SPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLL
NRAQCNRNIGHFLFWHLRSEMHMPAVAVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKS
VNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEK
CRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDGTRGCISMVLIMNHWNKMCLCRIVPYG
CLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
THDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A8C3XTY8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelydra serpentina|TrEMBL
LGFSSIMPPAMTDILDIWAVDSQVGADGLISVDFLLPTGTYINLDVPRDATICHIKQLLW
KQAHSYPLFHLLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLKLVTRNCDPGE
KLDSKIGVLIGKGLHEFDALQDPEVKEFRSKMRRISEEKLLSLVGLSWLDWLKHSYPPEQ
EPSIPENFQDKLYGGNLVVAIHFDKCQDVFSFQVSPNINPVKLNELAIRKRLTIHGKEEE
VDPYDYVLQISGRLEYIFGDHPLIQFQYIRKCVMNRTLPHLTLVECCSIKKMCEQEMIAI
EAAINRKSSNLPLPLPPKKTRTSVWDNSNPFKIMLLKGNKLNTEETAKVHVRAGLFHGTE
LLCKPIVSAEIFGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKTINP
SKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDFLLHSWTSFPDELEEMLNPMGTVRTN
PYTENATALHIKFQEYSKLPIYYPPFDKILEKAAEIAKSSENAGMAGRGGKKFYIELKEI
MERDPLTQLCENEMDLIWTLRYDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWSKL
PPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLV
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGVILEAYCRGSIAHMKVLSKQVEALNKLKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELYVEKCKYMDS
KMKPLWIVYNNKMFGGDLLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGC
LATGDHSGLIEAVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C3T2K5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelydra serpentina|TrEMBL
MPPAMTDILDIWAVDSQVGADGLISVDFLLPTGTYINLDVPRDATICHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVKEFRSKMRRISEEKLLSLVGLSWLDWLKHSYPPEQEPSIPE
NFQDKLYGGNLVVAIHFDKCQDVFSFQVSPNINPVKLNELAIRKRLTIHGKEEEVDPYDY
VLQISGRLEYIFGDHPLIQFQYIRKCVMNRTLPHLTLVECCSIKKMCEQEMIAIEAAINR
KSSNLPLPLPPKKTRTKNFQPALMFLSKYSWHVFGYFSVTPLLQVHVRAGLFHGTELLCK
PIVSAEIFGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKTINPSKYQ
TIRKHYPVAWVNTMVFDFKGQLKSGDFLLHSWTSFPDELEEMLNPMGTVRTNPYTENATA
LHIKFQEYSKLPIYYPPFDKGLRPKSAPVSPLKFYIELKEIMERDPLTQLCENEMDLIWT
LRYDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWSKLPPREALELLDFNYPDQYVR
EYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLVERALANRRIGQMLFWHLRS
EVHIPAVSVQFGVILEAYCRGSIAHMKVLSKQVEALNKLKTLNSLIKLNAMKQSKAKGKD
AMHTCLKQNAYREALSDLQSPLNPSVILSELYVEKCKYMDSKMKPLWIVYNNKMFGGDLL
GIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGCLATGDHSGLIEAVSASETI
ADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSCAGYCVATYVLGIGDR
HSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFG
RFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQ
FKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K5VXY0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hylia prasina|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQHEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGRGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGI
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
WEVAVCSEPVWRQRLDFDISICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>K9IPS4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Desmodus rotundus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
SFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSTRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C4J107|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dromaius novaehollandiae|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHTY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIQE
SFQDKLYSGNLVVAIHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPTD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLIECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDICNPFKIILLKGYKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKVKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELILHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAXSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCKYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGR
>A0A6P5K8G9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phascolarctos cinereus|TrEMBL
MCFSFIMPPAMADILDFWGVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISNIKQMLW
KQAHNYPMFNLLMEIEAYMFACVNQTAVYEELEDETRRLCDIRPFLSVLKVVTRNCDPGE
KLDSKIGVLIGKGLHEFDALEDPEVNEFRSKMRQFSEEKIQSLVGLSWMDWLKHTYPPEQ
EPSIPENLEDKLYGGNLVVAVHFENCQDVFSFQVSPNMNPIKLNELAIRKRLTIRGKEDE
VDPYDYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPKLTLVECCNIKKMCEQEMIAI
EAAINRNSSNLPLPLPPKKTRLISNVWENTQPFQIILVKGTKLNTEETVKVHVRAGLFHG
TELLCKPVVSSEISGRNDRVWSEPLEFDINICDLPRMARLCFAVYAVDKVKTKKSTKTIN
PSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKAGDIILHSWSSFPDELEEMLNPMGTVQT
NPYIENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSGNVSSRGGKKFHAVLKEI
MERDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWPKL
PPREALELLDFNYPDQYVREYAVSCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFML
DRALANRRIGQFLFWHLRSEVHIPAFSVQFGVILEAYCRGSVGYMKVLSKQVEALNKLKT
LNSLIKLNAVKLNKAKGREAMHTCLKQNAYREALSDLPSPLNPCVILSELYVEKCKYMDS
KMKPLRIVYNNKVFGGDPVGIIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGC
LATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDQAIEEF
TLSCAGYCVASYVLGIGDRHSDNIMVRKTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFNRFRKCCEEAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKVFYCCSAAIYRLQSYLSSISSPLIQRGVNSLASTFEKLSARAAI
>A0A6J3JPU0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sapajus apella|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLNGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRTKMCQFCEEAAACRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHFSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLDQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISISDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLHMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
YPVYYPPLEKILELGRHSECVRVTEEEQLQLREILERRGCGELYEHEKDLLWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLGALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSSGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7K6GPD9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Malurus elegans|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQILQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVSCRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQKRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKESWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQEVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A0A1UEI9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Entamoeba invadens IP1|TrEMBL
MSRKLLRSSVAVKSTVSESVVHVVFKKDDHVYIYTFPATSTAFGIKNAIKSEMKLEGTYS
IVIPSIPFKVVDAMEDTVIKEMGFYDTCVKFGLFPTFEMVNREIAESYESVAGLSKLMTK
LSANYQTIGQNYVDVLRTDVEEIFVFRRSLARVRLISNSLEEKYDRKIHEENEYAYTLSE
PNLPTSVNKLDIRVVGTDLNLTAVFKVTPDVKVQKFINAIYVEFMKKSPMKMSGYNTTSF
VLKVMGYDEYIIPKKVDGKEWLLSDFDYIRRQGIRGESLQLELVPRDNLLKCMISEEDVK
TMKYLDTFFASEYWEAFDEEKRCSQRQCTDQFSMVITSVENLVYLSKKKGNKSKKEKKEK
EEEESTLIVKDENQEDEEVERVTDFLGYISAELFYGEISLCPAIYSPVFEIKNGLANPKW
KATFVQLLATLPAESKVIYSVYKTDKVVNTVVTEVSEEDKCVGTVNTRVVNYLNDLISGA
QQYTLWQSEPNPIAMCCNAVSSQEKLCVEYPILTNPVRMDTFITKKKEMETNMCSQNQQP
MGVDEVNAFNKIVHADALAVFTKEELKCLWEQRYTILKSKPQALARLLNSVNYTQPSEVH
EMHRLLARWPLLQPEEAIELLDFRYPDPQIRAFALRCIDTMTDDQLVMYLPQLVQALKFE
LHHHSALASFLLRRSLKNRRRIGHNFFWFLKAEIHDARVTARYGVLLEAFLVGCGNYKVE
LEKEVVFQSQLVVIANEVKDVANKDEQTELLKSSLGKLKYPDEMSLPLDSRFRIKKTVPN
TGKVFSSKKKPLMLVLQNADPLGEAIVVIQKVGDDLRQDILTLQMIRLMNGIWKNNGLDL
CMLPYLCIATGNEIGMLELVKNSETYGKIMAMDEKKLSVFRETAMTTWLKDQCSSPDSKV
QFELAVENFTYSCAGYCVATYILGIGDRHSDNVMLTKEGKFFHIDFGHFLGNFKKKFGVK
RERTPFKFTPHFANVMGGKGSPQFKKFEKVCIDAFITIRQHGPLFIYLFRLMLATGIPEL
QKVNDIEYMRNMFMFDKNDQEAGEEFRKLIYKCLDAWSQTFNDAVHDFVHYKKLPMFK
>A0A8C7ZUX4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias sinensis|TrEMBL
MHPGIYGMLEEWEDGDQEINMDFLLPTGIFLKFPVSRNDTIKHIKEMVWRNARSEALFSG
LGDPDGYVFTCINQTAEREELEEEFRRIRDVKPFMCVLRLVAREGNRQEKLTNTQITQLI
GKGLHEFESQKNHEVNEFRTKMRTFCEEKALERQYLPWQRWLEYSFPCDLEPCRTPSGFG
SVKLKSSKIFINVKFEASDESFMLQQDCQDLPVALMKSALKKKATVFRSLRQEPEDYILQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPQLTMVHHSTVSRFQEEQSRMCNQMFKSRSL
SRPPPLPLKRLVVQAGLFHGSELLCKVVTSLDVTVCSEPLWDQRLEFDINVCDLPRMSRL
CFALYAVIEKTKKPKSTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSMWPSVPDDKS
DLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPSLEKIIDFEKNGDVACTHKEEHLK
LKEIMDNKHYTEFFEDEKDLLWKLRTEIREHYPENLSKLLLVTKWNKREDVVQMVSLLKK
WPDLPAIHALELLDYSFPDPAVRSFTVRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLT
TFLLERALSNRRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIKILNKQNEALA
KMRALSDFVKSGSQKMTVEDLKLCIRQETYMEALSDLLSPLNPSIILTEICADKCRFMDS
KMKPLWLMYKNPSTPGDMVGIIFKNGDDLRQDMLTLQMIQLMENMWKKEGLDLRMIPYGC
LSTGNKMGLIEVVKNSDTIANIQLNSSNSAATAAFNKDALLNWLKSKNPGDKLEQAIEEF
TLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILT
YDFVHVIQQGRTNNSEKFERFREYCEQAYKILCRNGMLFVNLFAMMKAAGLPELTCFKDI
QYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRA
>Q546P7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|TrEMBL
MPPGVDCPMEFWTKEESQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IAKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLRVSNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYA
LQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGRITEEELQLREILERRGSGELYEHEKDLVWKMRHEVQEH
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDSSFPDCYVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLHSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQ
ETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A8J1KR78|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus laevis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMVVVLECLREATLVNIKHELFKEARKYPLYH
LLQDESSYIFVSVTQDAEREEFFDETRRLCDLRLFQPFLKVVEPVGNREEKILNREIGFA
IGMPVCEFDMVKDSEVQDFRKNVLNVCKDSVELRDANGPISRALYVYPPNVESSSELPKH
IESKLDKGQIIVVIWVIVSPNNEKQKYSLKINHDCVPEHVIAEAIRKKTRSMLLSTEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYNQIPVD
IFTMPSYSRRISTAAPYMNGEASAKSLWAINSTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGVEPLCDNVNTQRVPCSNPRWNEWLLYDMFIPDLPRAARVCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVSGSNPNKETPCLELEFDCF
SSPVKFPDMTAIEDHANKVLERELGYNYSHSGLSNRIVRENEVRENDKEQLRAISNRDPL
SEITEQEKEFLWSHRLYCRNIPEVLSKLLLSVKWNCRDDVSQMYCLLKEWPAIRPEQAME
LLDFNYPDRIVRSFAVSCLEKYLTDDKLSQFLIQLVQVMKYEQYLDNHLVRFLLKRALVN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSKQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMKRPDFMDALQGFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSEMLFLNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRCSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGETYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDNGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGIQECTKTRDFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKHL
>A0A1S3GKR9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dipodomys ordii|TrEMBL
MSPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHHAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRVKMRQFCEEAAVHRQQLGWEAWLQYSFPLQLEPSSRSWGA
GSPRTPNRTLLVNVKFEGSEESFTFQVSSKDKPVALMACALRKKATVFRQRLAERPEDYA
LRVNGKQEYLYGSHALCQFQPSSVSLWSLEQAFCVELVQGSKVNADERMKLVVQAGLFHG
SEMLCKTVSSSEVSVSSEPVWQQRLEFDISVCDLPRMARLCFALYAVVEKTKKARSTKKK
SKKADCPIAWANLMLFDYKNQLKTGEHCLYMWPSVPDEKGELLNPVGTVRSNPNTESAAT
LLICLPEVSPHPVYYPALEKILELGRPGERMRATEEEQLQLREILERRGSGELYEHEKDL
VWKLRHEVLERFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDC
HVGSFAIKSLRKLTDDELSHYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWH
LRSEMHVPSVALRFGLIMEAYCRGCTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQ
TKELMHLCMRQDAYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSNEEAGS
AGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLH
SDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLG
IGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGRTNNS
EKFERFRGYCEKAYSILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEE
ALKHFRVKFNEALRESWKTKVNWMAHNVSKDNRQ
>A0A674MRL3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
MPPGKYGMQEEWEKEGDQRIVMDFLLPTGIFLKFPVSRNDTIRTIKKMVWKNAQSEALYA
ALGDPDSYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVARVGDRVEKLTNTQISQL
TGKGLHEFEAQKNHEVDEFRAKMRTFCEEKAQERQVLPWLQWMECNFPCELEPCSSPVEC
GGVKSKNTKIFINVKFEASDESFMLQQDPQDLPAALMRAALKKKATVFRSVRQEPEDYTL
QVNGRWEYIYGRHPLSQFKYIFSCLRNSQNPHLTMVHHSTIRKYQEEQGRACSQAYKCHR
PSRPPPLPLKKNTSSLWSINEPFHIRLLHGSRVNAAEGMKLVVQAGLFHGSELLCKMVTS
TEVAVCSEPVWDQKLEFDINFSDLPRMSRLCFALYAVIEKNKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIQFPNVRP
HPLYYPPLEKVPVPAQVRRLRKTKEIMDNKNYTEIFEDEKELLWKLRSVVCDHYPESLSK
LLLITKWNKREDVVQMVGLLRYWSDLPAIHALELLDYSFPDPAVRAFTIRCLRKLSDEEL
LQYLIQLVQVLKYESYLDCDLTTFLLERALSNSRIGHFLFWHLKSEIHVPSVSLRFSLIL
EAYCRGNIWHIKLLIKQNEALLKMKTLSDIVKSGSQKMTVDDLKLCIKQESYLETLSDLL
SPLNPSVVLAEICADKCRFMDSKMKPLWLMYKSPWAQGDMMGIIFKNGDDLRQDMLTLQM
IRLMEILWKKEGLDLRGKLEKAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFH
IDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCR
NGMLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKT
KVNWMMHSLAKDNRP
>A0A7K6I067|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dasyornis broadbenti|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSNFRTKMCQFCEEKAAKRQQLSWVAWMEYNFPLQLEPMAKGLGS
GPLQIPTKNIFVNVKFQSGGESFTFQISPSEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLDFDINICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQLRAAPEDSEEKQQLREILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEQTGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKREGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L1GJ01|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Indicator maculatus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHIPTKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWRQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAP
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKQQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGQVASLLFKEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A674H0Q8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MPPAVTDSLDIWAVDSQIAADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQETVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVEAGLFHGTELLCKTIVSTEIS
GRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKYQTIRKAGKV
HYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIR
FQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMERDPLSQLCEN
EMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPREALELLDFN
YPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQM
LFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAMKQ
SKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKPLWIVYNNK
MFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATGDHSGLIEA
VSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSCAGYCVATY
VLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKT
GNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSIKDIQYLKDSLALGKS
EEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A674GMJ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MEINVTFSALRYVPIFWFCFFFPSFISLFSLQLLWKQAHSYPLFHLLMEIDSYMFSCVNQ
TAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKIGVLIGKGLHEFDALQDPEV
NDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQETVIPESFQDKLYSGNLVVAVHFDN
CQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPADYVLQVSGRLEYVFGDHPLI
QFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAINRKSSNLPLPLPPKKTRATT
SVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLCKTIVSTEISGRSDHVWNEV
LEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKYQTIRKAGKVHYPVAWVNTM
VFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIRFQEYSKQPIN
YPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMERDPLSQLCENEMDLIWTLRY
DCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPREALELLDFNYPDQYVREYA
VGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQMLFWHLRSEVH
IPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAMKQSKAKGKDAMH
TCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKPLWIVYNNKMFGGDLVGII
FKNGDDLRQDMLTLQILRLMDILWKEAGLDLRDDLDRAIEEFTLSCAGYCVATYVLGIGD
RHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKF
GRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSIKDIQYLKDSLALGKSEEEALK
QFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A1A7WBF2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Iconisemion striatum|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREAALNTIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDSTGPHSRALYVYPPNVESTQELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYTQLPTD
SFVMPSYSRRISTATSYMNGEAASKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSVCSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPEMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNFPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHALHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNI
>A0A8C2H618|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLHH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSADLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKIAHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDEYFLEKHPLSQYKYIRSCITLGRLPHLMLVSKDSLYSQLPSS
GFMAPSYSRRTPQPSPCPGGADPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDEQQIEEHANWSISRELGYSYCLGLSSRLACDSSISQADAEQLRTLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQIYCLLKDWPLMQPESAL
ELLDCNFPDPMVRDFALRCLIQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIREKNKGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFERCEHTHTHTHTHICICGLQELSIGVMVFILYKLYFLLLYTN
PTPNPTPYRKLTIFEFLKTPFCIFFKAFCFTGTQEVSS
>A0A8C2E6V9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSLQ
INGRWEFIYGKYPLCQFKLISFFPLLQYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLS
NQVSRSRAQSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGS
ELLCKVVISNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNK
RADCPLAWVNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLL
IRFPNIRPHPLYYPPIEKLNDLGMNGEKTTKEEHMKLREIVDNKNYTEFFEDEKELLWKL
REEVRQRYPESLPKLLLITKWNKHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARS
FTIRCLRKLSDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSE
MHVPSVSLRFGLILEAYCRGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTED
MKVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQ
RNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMISETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRE
CCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVK
FNEALRESWKTKVNWMMHTFAKDNR
>A0A8C1DK00|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
IFRLRSDRCRKVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQT
LDCIRYWKALRKEVGKIHLVVRTQPNEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRR
KLLTPRKIELSDRDPKLYSMDPWITPKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSID
DTPVQRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKNGEEIHLVLEHP
PDPELDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRKFRVKILGIDI
PVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIKIKDLPKGARLS
LQVSCGKAQTQTSKENECKNKSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPEKSEDNSS
VNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERGQREMPNHLRKQ
FEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEAVMITHHLLERC
TVWDRSSLDVGLAIQLLDCHFSDEKVRTMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHD
SALARFLLKRALRSQRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGEAMLQDFRK
QVEMTEALQKVTREIKLMSAEKYDVSQQVVLQLRQKLEGLQTSGLPDSFKVPYDPGLRAG
ALVIEQCKVMASKRNPCGCSSNEPTPQHSVMTNIISAISQTDHCSSQILLIMESIWELES
LDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDEILSQWLREKCVNED
KHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNYCYYWNLSAMKWLLKEYFRF
SLPCFYFRYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKFCN
FAFKTKGGFSHPFPITTHMQMHTKHFKTIL
>A0A8C1PJW4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLHH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSADLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKIAHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQEGCNLVQELRLDDARFAADFRLDRVLCSYHIINSLSSETSAICLPASF
>A0A3P8U060|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amphiprion percula|TrEMBL
MDGQQIQVSDEEPEVLREESRRRRRRKKAITSSPCTSMDQISVEFVLPTVARGGNGPDSL
LLEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQQFSPDHCILLYQKKGNVCEIYDKHQVFQ
TLDCIRYWRALKKDVGRIQLVPRPQPSEESQQYQSYLNCLIGYDVTDVSNVHDDELEFTR
RKLLTPRRIELSDRDPKLYSMDPWVTRKPLHEHLRTKINNSHILVVIHISTASQTIKVSI
DDTPTQVLASFFAKTANKRVLLGIPENKCETDFVLRVCGREEYLYGEKPLQNFNWVRQCL
KNGEEIHLVLETPPDPELDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDC
NRKFRVKVLGIDIPSLPKVPEFVVFIEASIFHGQQLLAQERTTSKSFNEEVLWNCWLEFN
IKIKDLPKGARLNLQVICGKQPQTSNSKGGKTKSRLLYYVNLLLIDHRSLLRQGEFILHM
WKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDYGAAG
EEAEGGERGQREMPNHLKKQFEAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLG
SVRWGKQEDVLATHHLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDD
DVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYA
VLLEAYLRGCGENMLQDFRKQVEMTEALQKVTCEIKAMSDDKYHVTAQVVFQLRQKLETL
QASGLPESFRVPYDPGLRAGVLLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKD
GDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQS
VVGSTGAFKDELLCQWLRDKCVSEEKFQQAVERFLFSCGGYCVATYVLGIGDRHNDNIMI
TESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCV
KAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDDAQRHLLDQIEI
CREKGWMVQVNWFVHLVLGIKQGVEKRST
>A0A1A8PC15|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius rachovii|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREAALNTIKHELFKEVRKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDSSGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYTQLPTD
SFVMPSYSRRISTATSYMNGEAASKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSVCSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVASKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNFPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFW
>A0A670J8D9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podarcis muralis|TrEMBL
MPPGIACPVEFWSKEANQSIQVDFLLPTGIYLTLSISCNASLNTIKQMVWHHAQFEPLFH
MLSGPESYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDALSDPEVNDFRTKMHQFCEERVTRRQQLSWKAWMEYSFPVQLEPSSSSLGR
KSPLQVPNKNIFVNVKFESGGVNPFTFQISPKEFPVTLMSYAVKKQATIFRHQRMNSPEE
YALQVNGKCEYLYGNYPLYQFQVCAPLAYLSAHGLSAWRTHAQSCEVGWLCSPLSFISLS
QLVVQAGLYHGHEMLCKMVSSSEVNVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVE
KAKKGSLHWPGSTPRNKTRWCNQLKTGECCLPMWSSFPDEKGELLNPTGTVRTNPNTESA
AALVIRFPGILLYPVYYPSFEQVRRWWFAPLSLASLVCFLGQWKKVSHLHSLKEILERRS
HTELYEHEKDLVWKMRHQVRDQYPGALAKLLVVTKWNKHEDVAQMIHLLQSWPELPVLNA
LELLDFNFPDRYVGSFTVNSLKKLTDAELFQYLLQLVQVLKYESYLDCKLTTFLLDRALS
NRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKSLMRQSEALNKMKALNGIV
KLSALKNPKPQTKEFMHTCLRQETYLEALSNLQSPLNPSVILAKVSVELCTFMDSKMKPL
WIVFNNEEIGGTSNVGIIFKNGDDLRQDMLTLQMIQLMDILWKKEGLDLRMTPYGCLSTG
DKTGLIEVVMDSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALDRAIEEFTLSC
AGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFV
HVIQQGKTSNSEKFERFREYCERAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLK
DSLALGKTDEEARKHFQLKFNEALRESWKTKVNWLAHNVSKDNRQ
>S9YDK0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Camelus ferus|TrEMBL
MSSYGSRIGLGQEDRWIGGKKLESEGSTEMFEKTKPQRLGSSIPGREAGQQQQRGQEEKT
EQDDWYLRSKSRMPPGVDCPMEFWTKEENQDVAVDFLLPTGVYLNFPVSRNANLSTIKKV
LWHRAQYEPLFHMLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDR
VKKLINSQISLLIGKGLHEFDSLQDPEVNDFRAKMRQFCEEAAVRRQQLSWEAWLQYSFP
LQLEPSARSWGPGTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVF
RQPLVEQPEDYTLRVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDE
QSNPASQVQKPRTKPPPIPMKKLASCLHPAQPSSVSLWSLEQPFCIELIQGSKVNADERM
KLVVQAGLFHGNETLCKTVSSSEVSVCSEPVWKQRLEFDINDCPIAWANLMLFDYKDQLK
TGECRLYMWPSVPDEKGELLNPSGTVRSNPNTESAAALVIFLPEVAPHPVYYPALDKILE
LGRHGEHGRFTEEEXXXXXXXXXXXXXXXXXXXXXXXSVEQCTFMDSKMKPLWVMYSNEE
AGSDGSVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEV
VLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATY
VLGIGDRHSDNIMVRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKT
NNSEKFERFRGYCERAYSILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKT
EEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8B8U9U3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Camelus ferus|TrEMBL
MPPGVDCPMEFWTKEENQDVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEAAVRRQQLSWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LRVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPASQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECRLYMWPSVPDEKGELLNPSGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTPKPQTKELMHMCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYSILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7L0G4V0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Herpetotheres cachinnans|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSSLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFINIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIVGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRVTSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A670J8R3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podarcis muralis|TrEMBL
MPPGIACPVEFWSKEANQSIQVDFLLPTGIYLTLSISCNASLNTIKQMVWHHAQFEPLFH
MLSGPESYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDALSDPEVNDFRTKMHQFCEERVTRRQQLSWKAWMEYSFPVQLEPSSSSLGR
KSPLQVPNKNIFVNVKFESGGESFTFQISPKEFPVTLMSYAVKKQATIFRHQRMNSPEEY
ALQVNGKCEYLYGNYPLYQFQYIRDCLHRGLLPHLTMVHSTSIMALWEEQTNGITHPSKA
SPKPPPVPKKKPNSISLWSLEQPYYIDLVQGSKVNADERMKLVVQAGLYHGHEMLCKMVS
SSEVNVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIA
WVNIMLFDYQDQLKTGECCLPMWSSFPDEKGELLNPTGTVRTNPNTESAAALVIRFPGIL
LYPVYYPSFEQGERGRLKQQLKEILERRSHTELYEHEKDLVWKMRHQVRDQYPGALAKLL
VVTKWNKHEDVAQMIHLLQSWPELPVLNALELLDFNFPDRYVGSFTVNSLKKLTDAELFQ
YLLQLVQVLKYESYLDCKLTTFLLDRALSNRKIGHFLFWHLRSEMHVPSVALRFGLILEA
YCRGSTHHMKSLMRQSEALNKMKALNGIVKLSALKNPKPQTKEFMHTCLRQETYLEALSN
LQSPLNPSVILAKVSVELCTFMDSKMKPLWIVFNNEEIGGTSNVGIIFKNGDDLRQDMLT
LQMIQLMDILWKKEGLDLRMTPYGCLSTGDKTGLIEVVMDSDTIANIQLNKSNMAATAAF
NKDALLNWLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHI
DFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFREYCERAYMILRCH
GLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEARKHFQLKFNEALRESWKTK
VNWLAHNVSKDNRQ
>A0A2K6GVR8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Propithecus coquereli|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSCNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARGWGA
GTLRLPNRAFLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGRHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQGQKPR
TKPPPIPVKKPSSASLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRGNPNTESAAALVICLPEVAP
HPVYYPALEKILELGRHGECGRVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEQAGGNSCVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A1U7RNE7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alligator sinensis|TrEMBL
MAHLLLLISSGMELGNHEQPVVMREENKRRRRRMKPYCTANNLSSMELIPIEFVLPTSPK
HTKTPEIVTLEIAGNCTVEQMKAQIWMHAIEMSQTSDFCHKYTPDQFILQYQKKGQWYEI
YDKHQVIQTLDCILYWKVLQKKVGRIYVVQKQKPSVEVQEFQKQLNDLIGYDVTDVSNVH
DDELEFTRRRLVTPRMIEVACRDPKLYSMHPWITSKPLPEYLFKKITNNNIFINIHRGTT
SQKIKISIDDTPDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPVKD
FHCIRQCLKNGEEIHLVLDTPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERV
FTISLWDCNRKFRVKIIGIDIPVLPRNTDITVFVEANIQHGQQLLSQRRTASKPFTEEVL
WNTWLEFDIKIKDLPKGALLNLQVYCGKTQSLSTKANLQSHDSPSSDSKCKTQLLYYVNI
LLIDHRFLLRSGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAVSIVLDKYCHP
IALPKHRITSDTQGDGARTEMPNQLRKQLEEIIATDPLNPLTAEDKELLWHFRYESIKHP
KAYPKLLSSVKWGQQDLVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQ
KLECLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQS
MHYQQRFAVILEAYLKGCGKAMLCDFMKQVQVIELLHTVTMEIKSVSAEKYDVTSQVITQ
LKQKLEKLQNNKLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNE
TIGIIFKHGDDLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDAT
TIAKIQQSTVGNTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGD
RHNDNIMITESGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSQHF
HKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKK
YFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3Q0GTS0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alligator sinensis|TrEMBL
MAHLLLLISSGMELGNHEQPVVMREENKRRRRRMKPYCTANNLSSMELIPIEFVLPTSPK
HTKTPEIVTLEIAGNCTVEQMKAQIWMHAIEMSQTSDFCHKYTPDQFILQYQKKGQWYEI
YDKHQVIQTLDCILYWKVLQKKVGRIYVVQKQKPSVEVQEFQKQLNDLIGYDVTDVSNVH
DDELEFTRRRLVTPRMIEVACRDPKLYSMHPWITSKPLPEYLFKKITNNNIFINIHRGTT
SQKIKISIDDTPDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPVKD
FHCIRQCLKNGEEIHLVLDTPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERV
FTISLWDCNRKFRVKIIGIDIPVLPRNTDITVFVEANIQHGQQLLSQRRTASKPFTEEVL
WNTWLEFDIKIKDLPKGALLNLQVYCGKTQSLSTKANLQSHDSPSSDSKCKTQLLYYVNI
LLIDHRFLLRSGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAVSIVLDKYCHP
IALPKHRITSDTQGDGARTEMPNQLRKQLEEIIATDPLNPLTAEDKELLWHFRYESIKHP
KAYPKLLSSVKWGQQDLVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQ
KLECLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQS
MHYQQRFAVILEAYLKGCGKAMLCDFMKQVQVIELLHTVTMEIKSVSAEKYDVTSQVITQ
LKQKLEKLQNNKLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNE
TIGIIFKHGDDLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDAT
TIAKIQQSTVGNTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGD
RHNDNIMITESGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSQHF
HKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTTPLAF
>A0A7L3G5K9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anhinga rufa|TrEMBL
MDLGDYEQPVVMREENKRRRRRMKPHCTSSSLSSMELISIEFILPTSNKHTKVPEMMVLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPILPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHTKENVRAMAVQK
LESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSM
HYQQRFAVILEAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQL
RQKLEKLQNSKLPESFRVPYDPGLRAGALVV
>A0A8C5KRA0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Jaculus jaculus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEEWLQYSFPLQLEPSARGWGA
GTLRIPNRTLLVNVKFEGSEESFTFQVSTKDLPLALMACALRKKATVFRQPLLDRPEDYA
LQVNGRHEYLYGGYPLCQFQYICSCMHSGLTPHLTMVHSSSILAMRDEQSNPTPQVQKQR
TKPPPIPAKKPSCVSLWSLEQPFFIELVEGSRVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRMEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
QPVYYPALEKILELGRHGERGRVTEEEQLQLREILERRGCGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQSAQMIYLLCSWPELPVLSALELLDFSFPDCYVGSFAI
RSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHV
PSIALRFGLIMEAYCRGSTHHMKVLMRQGEALSKLKALNDFVKVSSQKTTKPQTKELMHL
CMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSTGSVGII
FKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANI
QLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFR
GYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRV
KFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C5P598|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Jaculus jaculus|TrEMBL
MCVNVIMPPAMADVLDIWVVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISFIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEEKIQSLVGLSWIDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIHGKEDE
ASPYDYVLQVSGRIEYVFGDHPLIQFQYIRTCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWDNNNPFQIILVKGSKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANMSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A091SVA3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pelecanus crispus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNHPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQANCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRTGEPPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQHPQALAKLLIITKWNKHDDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLR
>A0A8C9YXE8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSSVKYPDMNAIEEHANWTISRELGFNYNLSGQSNRSARDHALTENDTEQMRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPSTRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8D0AIU7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
LLRRGVHLSAYGQPKALREDTRRRRRKKAIMSSSCTSMDQISVEFVLPTAARGGNNPDTL
LLEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQ
TLDCIRYWRALKKDVGRIQLAPRPQPSDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRRIQLADRDAKLYSMDPWVTRKPLPEHLLSKISNGHILVVIHIGTASQTIKVSI
DNTPAQVTNVLQLESKLLGVCQHREEYLYGDKPLQDFNWIRQCLKNGEEIHLVLEAPPDT
DLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVLGIDIPSL
PKIPEFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLEFNIKIKDLPKGARLNLQC
FLKPNMTSSRKIKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEESSSSINADKLT
SATNPDKASAMAVAILLDKYCYPVVLPKSRDVGRDAATGCEEAEGGERGQREMPNHLKKQ
FAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRWGKQEDVLATHRLLERS
SAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHD
SALVRFLLKTALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRK
QVEMTEALQKVTREVKAMSADKCDITAQVVFQLRQKLETLQSSGLPESFRVPYDPGLRAG
ALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQDMLILQILLIMESI
WETESLDLCLLPYGCISTGNKIGMIETVKDATTIANIQQSVVGSTGAFKDEILCQWLRDK
CVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKS
FMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMM
LMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQINWFVHLVLGI
KQGVEKRST
>A0A7K8UD26|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oceanites oceanicus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVLWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCHFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRRETVQNPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRCLTPHLTMVHSSAIIAMRDEQTNCIASPPKTA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFNFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMRSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A4W3K916|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPAMTDPLDIWAVDSQIPADNSITVDFLLPTGIYIQLDVPREATIDQIKMLLWRQAQTY
PLYTVLGEKDSYMFQCVNQSAVHEELEDESRRLCDVRPFLPVLKLVARNCNRSERLLDSK
IGVLIGKGLHEFDALTDPEVREFRSKMRMFNEEKMLKLQGLSWMDWLKHSFPPELESTAF
NNFEDKLPKENLVVAVQFDSCQENFSFQISPNLNPLDLNELAIRKQLTIHGKENEEFNPR
DFVLRVSGKQEYLFGEQPLIQFRYIRNCVLKGSNPQLTLVDCCTIKEMCDREMSAIGVAL
HRKISNAPLPLPPKRRTISVSTQSLRTSLAGIFHGTELLSKSVVSTEVSGKNDLVWNEIL
DFEINLCDLPRMSRLCFAVYGVMDKVKKQKSTKNASKYQTIRKHYPIAWVNTMVFDFRAQ
LKSGDLDLHCWSSFPDEMEDMLNPMGTVQTNPYSENAASLHIQFQEYSKSVIYYPAFDKG
RGGKKLHIELKEIMERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDV
AQLQALLQIWIKLCPRDALELLDFNYPDQYVREYAVKCLKEMSDEELSQYLLQLVQVLKY
EPYFDCALSRFLLERAQANRRIGHFLFWHLRSEMHLPATSLQFGLILESYCRGSFTHIKE
LSKQMEALSKLKAINNLVKLSYLKVTRTKVKEVMNTCLKQPVYTEALSDLQSPLNPSVIL
SKLNVDKCKFMDSKMKPLWILYNNKMSGGEPVGIIFKNGDDLRQDMLALQILRLMDMLWK
EAGLDLRIVPYGCLATGDKSGLIEVVSASETIANIQLTNSNVAATAAFNKDALLNWLKEK
NTGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRETGQLFHIDFGHILGNFKSK
FGIKRERVPFILTHDFIHVIQQGKPGNAEKFGRFRQCCEEAYLILRKNGNLFITLFALML
TAGLPELSSVKDIQYLKDSLALGKSDDEALKQFRQKFDEALRESWTTKVNWMAHIVAKDN
RS
>A0A4W3KJ21|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MESLNRDGHSQANTSSGKVEEEYNQCEFNSFMNLSTVVFDCVLPTKKLNDDQNEVITVEI
PGNSTVRHLRILTWMQATRDSASPSIYTLTHPNSYQFLYKKGLRWYEIYDDHQIIQTLDS
VRYWKNSGMKKGSIYIKSNPKETEESDKLQKKLTYLIGYDIRNIVTHRRNELSFAQRKLA
SSRQVELSSRDVRAYAMEPWVVSSPLSKSLMDLTGEGLVIAIHYNDSSHKMKVGITDTPV
EIIHSYMQKMADKGWPIHHPEDNLAFKVCGREEHITGGRPLIDFIWIRRCIKNKEDIRLM
LVLAPCTEDDEVDTDDWPLVDQHTGLCGTHDELTLRNKDIDQILVLSLWDCNSRFRVKVV
GIDCPALPHKSLPHIYVEACILHAKTILSSARSQPLPFTEEVIWNIWLQFDILVKNLPRG
SRLSFFIYGMDFESLSTRDAKTPPQRVEDGGFYKGRTKLLYFVSFLLIDHRSFLQQGEHI
LHMWPYADREEDLFTHEADKLSSKTNPDVDNSMAICIMLDTYSHPLVLPTGRTSRSSCIN
QMSEDAELTSTMNIRCKKLPLPLTVSEKNLQFTEQCSQYGNSLPNILSSVKWGKLEAVEE
AHCLCEHWNSQQLDIAIALELLSISFADEKVRNLAVQRLEELDNNELLRYLLQLVQALKF
EPYHDSALARFLIRCGLRSKRIGHFFFWYLRSEITGSPYFCDRFAVILEAYLLGCGKSML
DEFYKQVQVVESLHQVATDIKKIIPEKNDLPPNAASLLQDMLRKADLPQSFLVPYDPRIK
TSGILLERCRIMASKKKPLWLEFSCGDEDSAHCQPVGIIFKHGDDLRQDMLIIQTLVIMD
SIWQENSLDLNLVPYGCISTGYNIGMIEIVRDATTIAAVQRSQGGTTAAFKNEALHEWLR
SRLQVEESYYQAMETFVTSCAGYCIATYILGIGDRHNDNIMVTAQGNLFHIDFGHILGNT
KRFLGVNRERAPFVLTPDFLFVMGKVNKRSSLYFQRFKDICIEAYLSLRAHSKLLVNLFS
LMTLTGIPELTSTKSIQYLKEALAMEKDEKMAQEHILNQIEMCESLGWTVQANWWIHMFM
GVKQTKS
>A0A674JF79|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Terrapene carolina triunguis|TrEMBL
MPPAMTDILDIWAVDSQIGADGLISVDFLLPTGTYINLDVPRDATICHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVKEFRSKMRRISEDKLLSLVGLSWVDWLKHSYPPEQEPSIPE
NFQDKLYGGNLVVAIHFDKCQDVFSFQVSPNINPVKLNELAIRKRLTIHGKDDEVDPSDY
VLQISGRLEYIFGDHPLIQFQYIRKCVMNRTLPHLTLVEYCSIKKMCEQEMIAIEAAINR
KSSNLPLPLPPKKTRTVTQLTQSVWDISNPFKIMLLKGNKLNTEETAKVHVRAGLFHGTE
LLCKPIVSPEISGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKTINP
SKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDLLLHSWTSFPDELEEMLNPMGTVRTN
PYTENATALHIKFQEYSKLPIYYPPFDKILEKAAEIAKSSENAGMAGRGGKKFYIELKEI
MERDPLTQLCENEMDLIWTLRYDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWSKL
PPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLV
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGVILEAYCRGSIAHMKVLSKQVEALNKLKT
LNSIIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSIILSELYVEKCKYMDS
KMKPLWIVYNNRMFGGDLLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGC
LATGDHSGLIEAVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKTEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A2G9QNF1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lithobates catesbeianus|TrEMBL
LEAGMALENYDQPVVLRDENKRRRRKMRPHSAATSNVFSMELIPIEFILPTSHKNSKVPD
TILLEIAGNCTVEQMKAQVWMNAIEKSHNSDFYHRLSPDQFLLQYQKKGQWYEIYDKHQV
IQTLDCIMYWKVLQKTVGKIYIIQKQKSSEETVEYQKKLNYLIGYDVTDVSNVHDDELEF
TRRRLVTPRMIELVKRDARLYSMDPWVTSMPLSEHLSKKLTSNNIFIIIHKGMTSHTIRV
SIDDTPDEVLQSFFTKMAKKKSLLDISEEHSEQDFVLRVCGRDEYIIGNSPLKDFFYIRQ
CIKSADEIHFVLDLPPDPSEDIVQKEEWPLVDDCTGVTGYHEQLTIEGKDHEKIFTISLW
DCNRKFRVKIIGIDIPVLPRNTELIVFVEANIQHGQQVLSQRRTSCKPFTEEVLWNTWLE
FDIKIKDLPKGALLNLQIICCKAQTVSNKGTPHAADATGSDSKCKNQLLYYVNLLLIDHR
FLLRQGEFVLHMWKIPGKGEEQGSINADKLTSATNPDKDTSMAISLSLDKYCHPVALPKH
KSVSDPELDRARSEMPNQLRKQLEEIISTDPLHPLTPEDQELMWHFRYEVMKHPEAYPKL
LNSVKWGDQEMVAKTYQLLNKREAWDDCSLDVGLTIQLLDCNFSDENVRAMAVQKLECLQ
NDEVLHYLLQLVQAVKFEPYHDSALSRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQR
FAVILEAYLRGCGTAMLNDFIKQVQTTEVLHKVTMEIKSVSAEKYDVTSQGKC
>A0A3B4EI78|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pygocentrus nattereri|TrEMBL
MEPHISDDEPPVVHREENKRRRRKMKAFTSASSVAMDHLAMEFVLPTTNKTTRSPDSLQL
DVVGNWTVEQVKAQLWLRAVTTNLCPEFYQKYSPDHCILLYQKKGSWCEIYDKHQVFQTL
DCIRYWKALKKDVGKIHVVLRPQPSDESVQYQKFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELADRDPKLYSMDPWITTKSLPDYLLSKVTNNYILLVIHVYTSSQTIKVSIDD
TPVQVLQSFFTKIANKRALLGIPEEVNESNFVLRVCGREEYIYGNYAIKDFHWIRQSLKS
GEEIHLVLEPPPNPEQDVVQKEDWSQVDDCTGVAGTHEQLTIDEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTSPKPFTEEVLWNTWLEFNIK
IKDLPKGARLNLQVLCSKGQTQTSRDSATHDCRNKSRLLYYVNLLVVDHRSLLRQGEFIL
HMWKMPEKSEDNSSVNADKLTSATNPDKTSSMAIAVLLDKYCYPVALPKSRDSRDSSEMD
GERGKREMPNHLRKQFEQIVATDPLHPLSSEDKELLWHFRQECMRHPTAYPKFLGSVKWG
KQEAVMATHQLLERSTTWDRSPLDVGLAMQLLDCHFSDANVRTMAVRKLETLGDDDVLRY
LLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEA
YLRGCGGAMLQDFSKQVEITEALQKVTREIKAVSAEKYDVSAQVILQLRQKLEALQTSGL
PESFKVPFDPGLRAGALVCFFCDSKEPLWAGQYEHILIILVIMESIWETESLDLSLLPYG
CISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDEILNQWLRDKCVNEDKYQQAVERF
VYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLT
PDFLYVMGTTGKKSSPNFLKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDI
EYIREALTVGCTEDEAQRHFLDQIEICRDKGWTVQFNWFLHLVLGIKQGVEKRSA
>A0A8B7JYX1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Apteryx mantelli mantelli|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWQHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRIKMRQFCEERAAKRQQLSWAAWMEYNFPLQLEPLATGLGT
GPLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMNYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCLANPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSIAS
HPVYYPSFEQLLELGRNGEQPRTALEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDGELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTREMMHV
CMKQETYVEALSDLQSPLNPNIILTEVCVEQCTFMDSKMKPLWIVFNNEETDGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LTKSNMVATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALAKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C6UT83|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neogobius melanostomus|TrEMBL
LNSPVALVAKRASMVWKNAKSEALFSALGDPDAYVFTCINQTAEREELEEESRRISDVRP
FMCVLRLVAREGDRVEKLTNAQISLLIGKGLHEFEAQKNHEVNEFRTKMRAFCEEKALER
QLLPWRLWMEYSFPCDLEPCCSPHEEGNNKKKNTKIFVNIKFEASEVSGFSLGCYSGILS
HEPQASSLTFQHYLFDKEQLCFEPEDYTLQVNGRWDFIYGDHPLCQFKVSLSNIHNLIFV
LNGQAPQLTMVHHSTISKYQEEQGRMSNQLFQSRSLSRPPPLPLKKVRQQVVSGNTKMII
ILSFPVSLQLVVQAGLFHGSELLCKVVTSSEVTVRSEPLWDQKLEFDISVSDLPRMSRLC
FALYAVIEKTKKPRGTKKKNKRADCPIAWVNTMVFDYKDQLKTGEFLLSAWPSVPDDKSD
LLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPLDKKNGDSNGDFALLVFRLQLLRL
KEIMDNKNYTEFFEDEKELLWKLRYEVRERYPESLSKLLLITKWNKREEVVLVLLRNWPD
LPAIQALELLDYSFPDPSVRSFTIRCLKKLSDPELLQCLIQLVQVLKYESYLDCDLTTFL
LERALSNQRIGHFLFWHLRSEIHVSSVGLRFGLILEAYCRGNIHHIKLLTKQNEALTKMK
ALSDIVKSGSHKMTVDDLKLCIRQESYMEALSDLLSPLNPSIILTQICADKCRFMDSKMK
PLWMMYRNPCFQGEMVGIIFKNGDDLRQDMLTLQMIHLMENLWKKEGLDLRMIPYGCLST
GNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPGDRLEQAIEEFTLS
CAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDF
VHVIQQGRTNNSEKFERFREYCEWAYKILCHNGILFVNLFAMMKAAGLPELTSSKDIQYL
KDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A7K6RMC2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhynochetos jubatus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWVAWMEYNFPLQLEPMAKGLGT
GPLHTSTKNIFVNVKFQSGGESFTFQISPEEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTILAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVFEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRNHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKSLNELVKVSSQKATKPQTKEMMHV
CMKQETFLEALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKIKVNWLAHNVSKDNRQ
>A0A8C9L966|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pavo cristatus|TrEMBL
DLCYCVFLTSGMFVHLLWKQAHTYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDV
RPFLPVLKLVTRNCDPGEKLDSKIGVLIGKGLHEFDALQDPEVNDFRSKMRRISEEKIQS
LVGLSWMDWLKHTYPPEQEPVVPENFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIK
LNELAIRKRLTIHGKEDEEIDPADYVLQVSGRLEYVFGDHPLIQFQYIHNCVMNRTLPQL
TLVECCTIKKMCEQEMIAIEVAINRKSSNLPLPLPPKKTRATTSELCNVNHSVWDFCFYF
LLLKIYPSWISSLKCNKNGSFHETFNKCFNGLLYQIVFLSSYFNCNLIVFFLKQLQALLQ
IWPKLLPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCAL
SRFLLERALANRRIGQMLFWHLRSEIHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEAL
NKMKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKC
KYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRI
LPYGCLATGDHSGLIEAVSGSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDR
ATEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERV
PFILTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELT
SVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A094L304|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Antrostomus carolinensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSSELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGTLALDKTEQEALE
YFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A4W4GXA0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MEQGSDDEPPIVLRKEDKRRRRKMKAFTSNSCMEMDHLAMEFLLPTTNKITKNPDMLQLS
VTGNWTVEQVKTQVWLRAVTTNLCPEFYQKYSPDHCILLYQKKGSWCEIYDKHQVFQTLD
CIRYWKALKKDVGKIHLVLRPQPSEESIQYQKFLNYLIGYDVTDVSNVHDDELEFTRRKL
LTPRKIELADRDPKLYSVDPWITTKPLPDYLLSKITNSHILVVIHKDTSSQTIKVSIEDT
PVQVLHSFFLKTANKRALLGLPEDVSESDFVLRVCGREEYIFGNYAIKDFHWIRQCLKSG
EEIHLVLETPPNPDQDVVPKEDWSQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRK
FRVKILGIDIPVLPRNSELIVFVEASIYHGQQLLAQERTLPKPFTEEVLWNVWLEFNIKI
RDLPKGSRLNLQVSCGKAQTQASKDSTGHDGRNKGRLLYYVNLLVVDHRSLLRQGDFILH
MWKMPEKTEDNSSVNADKLTSATNPNKTTSMAITVLLDKYCYPVALPKSRDSRESSDGEE
ERGNREMPNHLRKQFEQIVVTDPLHPLSIEDKELLWHFRQECTRLPTAYPKFLGSVKWGK
QEDVMITHRLLERSTAWERSSLDVGLAMQLLDCHFSDANVRTMAVRKLETLGDDDILRYL
LQLVQAVKFEPYHDSALARLLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAY
LRGCGEAMLQDFRKQVEITEALQKVTRDIKAVSAEKYDVSPQVVFQLRQKLESLQVSGLP
NSFKVPYDPSLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLTNDSIGIIFKDGDDLRQ
DMLILQILLIMESIWDTESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTG
AFKDEILNQWLRDRCVSEDKFQQAVERFVYSCGGYCVATYVLGIGDRHNDNIMITESGNL
FHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTTGKKTPFTVFLWVTSVWWMLC
>A0A6P4WXV9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera pardus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GPLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLLERPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSAILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSAPDEKGELLNPAGTVRSNPNTESAAALVICLPEVSP
YPVYYPALDKILELGRHGEHGRFSEEELQLREILERRGSGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPDLPVLSALELLDFSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMRQGEALSKLKALNDFVKVSSQKTTRPQTKELMHLCMRQ
ETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDSSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGPLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A1L8G3Z7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus laevis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMVVVLECLREATLVNIKHELFKEARKYPLYH
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVVEPVGNREEKILNREIGFA
IGMPVCEFDMVKDSEVQDFRKNILNVCKDSVELRDANGPISRALYVYPPNVESSSELPKH
IESKLDKGQIIVVIWVIVSPNNEKQKYSLKINHDCVPEHVIAEAIRKKTRSMLLSTEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKDSLYSQLPMD
SFTMPSYSRRISMAAPYMNGEASAKSLWAINSTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGVEPLCDNVNTQRVPCSNPRWNEWLLYDMFIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVSGSNPNKETPCLELEFDCF
SSPVKFPDMTAIEDHANKVLEREMGYNYSHSGLSNRIVRENEVRESDKEQLKAISNRDPL
SEITEQEKEFLWSHRLYCRNVPEILPKLLLSVKWNCRDDVSQMYCLLKEWPAIRPEQAME
LLDFNYPDRIVRSFAVSCNEKYLTDDKLSQYLIQLVQVMKYEQYLDNHLVRFLLKKALVN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSKQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMKRPDFMDALQGFTSPLNPAHQLGNLRLEECRLMSSAKRPLW
LNWENPDIMSEMLFLNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRCSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDNGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGMQECTKTRDFERFQEMCYKAYLAIRQHANLFINLFSMMLGCGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKHL
>A0A3B1IC70|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MPPAMTDQLDVWSDPGLDGDDQVAVDFLLPTGVYIQMDVPRESTIQQIKQILWKQAQDYP
LFSLLGAIDDHIFECVNQAAVHEELEDESRRLCDVRPFLPVLKLIARDCGRAERLLESKI
GVLIGKGLHELDALQDQEVKDFRSKMQRNSEEKMQCVQMMSWGEWLQSCFSPQIEPGPID
EIYDARNENDIKITMHYNQSQDTASLRVPLSCTVAELTEQALRKWLTTHGSEEDGGSLAD
YVLRVSSKLEFLFGEHALIHYKYIRMCLLAQEIPHLTLVHCSEVKSMFERELTSIGAMLT
RKTSNPPLPLPPKRRGMSQMHMCVWEINSIFKITLVRGIKVNAEETAKVQVRAGLFHGTE
LLCKPAVSSESSGRSEYIWNTSLEFDISVSDMPRMTRLCFAIYAVMDKGKKQKSTKNTAM
NKYQTIRKAGKVHYPIAWVNTMVFDYRGHLKTGDIILHTWSSFPDELEEMLNPIGTIQTN
PYTENATALQISFPEYSQCPVVFPPFDKILEKAAEIAGASDSMSMGRGGKKFHIELKEIM
ERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLS
PRDALELLDFNYPDQYVREYAVGCLKYMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLE
RAQTNRKIGHFLFWHLRSEMHMPAVTVQFALILEAYCRGCIPHIEVLKKQVEALSKLKAV
NELIKLGTIKSKNKTKDAQLKEAMMKCLRQTGFIETLSDLHSPLNPHILLAGVHVERCKY
MDSKMKPLWIVYHNKLLVGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVP
YGCLATGDRTGLIEVVSSADTIANIQKNSSNMAAAAAFNKDALLNWLKDKNPGDALEKAI
EEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPF
ILTHDFIHVIQQGKTGNTEKFGSFRQYCEDAYLILRKNGNLFITLFALMLTAGLPELTSV
KDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAHRS
>A0A7K9AV43|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dromaius novaehollandiae|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFSPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIISD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCAKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3Q1CFR8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amphiprion ocellaris|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRCKMLRISEERMQQVQMMTCTEWLQACFSPQLEPA
AGTAIMDGVNDRPSDLKVIIHFDQSQDSASLKVPSSSTPTELIEMALRKWLTTHRPEEEA
WKGQYMLRVSRCLDFLCGDHPLIQYKYIRTCLQAKEPPRLTLVHTSAVKAIFDKEISAIG
AVVSRKSSNPPLPLPPKRRVPTQVQTCVWDVSSPFKIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESSRRSDHTWKDSTLEFDISVCDLPRMTRLCIAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TVQTNPYTENATELHIHFLEYSSHSIIFPPFDKILEKAAEIARANDCAPVGRGGKKFHIE
LKEIMDRDPLSQLCENEKDLIWTLRHDCHENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLSPRAALELLDFNYPDQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAQGNRRIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALS
KLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGI
NVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAN
LDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSG
DDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A341BU53|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neophocaena asiaeorientalis asiaeorientalis|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
AKPPPIPLKKPASVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMQLCLR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKLPVEKAKPPAFGAKTSGLKLA
SYFEDGAGRGPPWLGSERRALPGEVLGRCPPGSLGAVLLGGSVTCPERVEVQGDGAPC
>A0A6P5JXC9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phascolarctos cinereus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVHAPHSRALYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASTKSLWGINSALRIRILCATYVNVNIRDIDKIYVRTGI
CHGGEPLCDNVNTQRVPCSNPRWNEWLMYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMSVIEEHANWTVSRELGFNYSHAGLSNRIARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C2IQE8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGSHSRALYVYPPNVESSSELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLSRLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTEADIEQLRQLSNRDPL
SEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNTLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSTTLHQWLKDKNRGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A8C2AC15|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVAQS
GKSRSVKKILVNVKFEGSEETFVLQQDPQDLPMLLKRNALRKKSTVFRAAKQEKPEDYTL
QVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQMSRTRA
PSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGMNGEKVVTTKEEMVGLLRKWPELPAIHALELLDYSFPDPHVRSFT
IRCLRNLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRSEMH
VPSVSLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMK
VCIKQDTYMEALSDVVSPLNPSIVLCELCTDKCKFMDSKMKPLWLMYKNKYDHVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRN
NSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECC
EQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIHGWNFSLE
>A0A6P6C3E6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pteropus vampyrus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQITSDGSILVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKLSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIILVKGSKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCLAVYAVLDKVKTKKSTKTM
NASKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIVLHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALYIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLVELKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQTLRKWSPLTP
LSIMRTAGSLGPWGRQGGGPINEKKWGKLQALLQIWPKLPPREALELLDFNYPDQYVREY
AVECLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEV
HIPAVCIQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAM
HTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGV
IFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIAD
IQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHS
DNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRF
RQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFK
QKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6P5BQK9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos indicus|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASMSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8C0T7K1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>E1BE66|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos taurus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPFLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLSSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A6P7RCB3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus caroli|TrEMBL
MPPAMADNLDIWAVDSQIASDGTISVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRRKMRKFSEAKIQSLVGLSWIDWLKHTYPPEHEPSVLE
NLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEDEASPCDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINR
NSSNLPLPLPPKKTRVISHIWDNNNPFQIILVKGNKLNTEETVKVHVRAGLFHGTELLCK
TVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQ
TIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVTLHSWSSFPDELEEMLNPMGTVQTNPYAE
NATALHIKFPENKKQPYYYPPFDKIIEKAAELASGDSANVSSRGGKKFLAVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALD
NRRIGQFLFWHLRSEVHTPAVSIQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLI
KLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPL
WLVYSSRAFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGD
RSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCA
GYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A671FLU0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinolophus ferrumequinum|TrEMBL
MELENDEQPVVLREDNRRRRRRMKPRGSAASLSSMELVPIEFVLPTSQRTSKTPETALLH
VASHANVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQIHVVQRHSPSEDTLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPRLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVLADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKIG
EEIHLVLDTPPDPAQDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGK
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVRVIEMLQKVTIDIKSLSAEKYDVSSQVVLQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVVEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLREKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKMSLHFQKFQDVCAKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A6J0V797|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pogona vitticeps|TrEMBL
MELDSGESPVVMRDDNKRRRRRMKPHSTASLSSTELISIEFVLPTGYMLIDIPSNCTVEQ
MKTQVWMRAIERNQNSDYYHKFTPDQFVLQYQKKGQWYEIYDKHQIIQTLDCMLYWKVLQ
KKVGKIHVVQKQKPTKEVQEFQKQLNYLIGYDVTDVSNVHDDELEFARRRLVTPRTIEVS
CRDPKLYSMHPWTTSKPLPQYILSRIINNNIFINIHRGTTSQKIKVGIDDTPDIILQSFF
AKMAKKKSLMNIPEDHCELDFVLRVSGRDEYIVGDMPIKNFHWIRQCLKNGDEIHLVLND
PPDPKEDEVQKEEWLLVDDCTGVSGYHEQLTIDGKDHERVFTISLWDCNRKFRVKIIGID
IPVLPRNTDLTVFVEANIQHGQQLLSQKRTTAKPFTEEVLWNVWLEFDIKIKDLPKGALL
TLQIYCGKAPALSTKANLQSPDPPSSDSKCKTQLLYYVNILLIDHRSLLRTGDYVLHMWK
ISGKAEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHKIASDPQGDRARAE
MPNQLRKQLEEIIATDLLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQEIVAE
TYQLLAKRDAWDHSTLDVGLPMQLLDCNFSDENVRAMAVQKLEVLDDDEVLHYLLQLVQA
VKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGK
AMLQDFLKQVQVIELLQKVTLEIKSLSADKYDVTPQVITQLKQKLEKLQDSKFPECFRVP
YDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTSVSSETIGIIFKHGDDLRQDMLILQ
ILRIMESIWEEESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEI
LNQWLKEKCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITEAGNLFHIDFG
HILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSPRFQNFQEICVRAYLALRNHTNL
LIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNDEDAKKYFLDQIEVCRDKGWTVQFNW
FLHLVLGIKQGVEKHSA
>A0A6P9DGW7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pantherophis guttatus|TrEMBL
MPPRPSSGELWGMHLMPPKILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVELRDANAPHSRALYVCPPNIESSDLPKHI
YNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDNVPEQVIAEAIRKKTRSMLLSPEQLKL
CVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMTKESLYAQLPLDT
FAMPSYSRRISTATPYMNGEASAKSLWAINSHLRIKILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLQYDMLVLDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFS
SPVKFPDMSVIEEHAIWIISREQGFNYNHAGLSNRIARDNELRDNDKEQLRAICTRDPLS
EITEQEKDFLWSHRHYCVSMPEILPKLLLSVKWNSRDEVVQMYCLIKDWPQIRPEQAMEL
LDCNYPDPMVRAFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQ
RIGHFFFWHLKSEMHNKNVSQRFGLLLDSYCRACGMYLKHLSRQVEAMEKLINLTDILKQ
EKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLWL
NWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSI
GDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDPAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAY
IRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C4U3Y7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Falco tinnunculus|TrEMBL
MPPGIYCPTEFWAKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLHISTKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQTTPKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADER
MKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVI
EKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGT
VQCNPNTESAAALVICFPSVASHPVYYPSFEQVGDTDAFLGRHRNSLALLVPGTWLVPSF
LLLPGTRLYGQLSPGYALSCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQY
PQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFFLQVHLD
HDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFG
LILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHVCMKQETYL
EALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQ
DMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVA
TAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQ
LFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMI
LRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRES
WKTKVNWLAHNVSKDNRQ
>A0A091JPP9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Egretta garzetta|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPSSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSHEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>Q4RYW3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tetraodon nigroviridis|TrEMBL
MPPAMTDLLDIWATHTPLAGHAPDQITVDFLLPTGIYIQFDVPREATIQEIKQLLWKEAH
SFPMFSKLGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELSAINDQEVKDFRCKMARISEERMRKIERMTYAEWLQASYSPQLELT
ADPAVMEGNDRPADLKVIIHFDQSQDSASLKISSTCSPKDLIAQAVRKWLTTHGPEEETL
KGQYVLRVSHCLEFLCGDHPLIQHKYIRTCLQAKEPPHVTLIHNNTVRAMFNREISAIEA
ALTPKSSNLPLPLPPKKRAPTTCVWDVSSPFRIVLVNASKVNAEETAKVQVRAGLFHGTE
LLCKPAHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTVQTNPYTENA
TALHISFPEFSSHPIIFPPFDKVIVVSPNQPFHSHHVFKGRGGKKFHIELKEIMERDALS
QLCENEKDLIWTLRCDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPRLSPRDALE
LLDFNYPDQYVREYAVNCLRDMSNDELSQYLLQLVQVLRYEPYYDCALTHFLLERAQSSR
KIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALNKLKAVNELIKL
GTIKNARSKTKEAMLTKEAMMTCLRQSGFSETLSDLHSPLNPNILLSGINVEKCRYMDSK
MKPLWIVYNNKLLLGDMLGIIFKNGDDLRQDMLTLQILRLMDTLWKEANLDLRIVPYGCL
ATGDRAGLIEVVSSADTIANIQLTSSNMAAAAAFNKDALLNWLKERNSGDALERAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMVRSNGQLFHIDFGHILGNFKSKFGIKRERVPFILTH
DFIHVIQQGKTGQAEKFGSFRQYCEKAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQ
YLKDSLALGKSDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A671L1H8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCFFIAVLPFWLCSKWHKTFSTGHHEFDSQKN
HEVNEFRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQSGKSHSGKKILVNV
KFEGSEETFVLQQDPQDLPMFLKRNALRKKSTVFRPAKQEKPEDYTLQVNGRWEFIYGKY
PLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRTRAQSKPPPLPLKRQN
TSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSNEVSVCSEPVWD
QKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLK
TGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKLNE
LGMNCEKVVATKEEMVCLLRKWQELPAIHALELLDYSFPDPHVRSFTIRCLRNLRNDELF
QYLLQLVQVLKYESYLDCDLTCFLLERALSNKKIGHFLFWHLRSEMHVPSVSLRFGLILE
AYCRGSIFLIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALS
DVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKDKYDHVGIIFKNGDDLRQDMLTLQM
IQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKD
ALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFG
HFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTL
FVNLFALMKAAGLPELSSSKDIQYLKVRIAQTVIIYYP
>A0A6J2AFY9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acinonyx jubatus|TrEMBL
MPPFHCLARPIRVDIHKVPAIALQVVQGMELDNYEQPVVLREDNRRRRRRMKPRSTTASL
SSMELIPIEFVLPTSQRNSKTPETALLHVAGHGNVEQMKAQVWLRALETSVATDFYRRLG
PDHFLLLYQKKGQWYEIYDKYQVVQTLDCLRYWQVLHRSPGQIHVVQRRAPSDETLAFQR
QLTALIGYDVTDVSNVHDNELEFTRRRLVTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLL
KKITNNCIFIVIHRSTTSQTIKVSADDTPGAILQSFFTKMAKKKSLMDIPESQSEQDFVL
RVCGRDEYLVGETPIKNFQWVRQCLKNGEEIHLVLDTPPDPALDEVRKEEWPLVDDCTGV
TGYHEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNADLTVFVEANIQHGQQ
VLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPRGALLNLQIYCSKAPVLAGKTSAETPSS
ESKGKTQLLYYVNLLLIDHRFLLRHGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKEN
SMSISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDK
ELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLD
CNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIG
HFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTDQVQVIEMLQKVTLDIKSL
SAEKYDVSSQVISQLKQKLENLQNSNLPKSFRVPYDPGLKAGALVIEKCKVMASKKKPLW
LEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCIST
GDKIGMIEIVKEATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSC
AGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFL
FVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIR
DALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>H3CB06|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tetraodon nigroviridis|TrEMBL
AMAPRPSSGELWGLHLMPPRILVDCCLPNAGMMVSLECLRETPLVSIKQQLFSEARKFPL
HHLLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIG
FAIGMPVCEFEMLKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNLESSPQLP
QHIYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQ
LRLCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCITVGRLPHLMLVSKDSLYSQLP
ASGFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTPLRVRLLCATYVNVNIRDIDKIYV
RTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAK
EEHCPLAWGNVNLFDYKDILVSGKVALSLWPVPHGLENALNPIGVASNPNKETPCVELEF
SWFNQTVVFLRAEIEETHDIRESGTSRCGQSTRLACDSSVSAGDAEQLRSLCSRDPLYEL
SEQEKDFLWRHSRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWSLMEPELALELL
DCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKSLTNQR
IGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQE
KKDETQKTQMKFLVEHMSRPDYMDALQGFVSPLNPVHQLGNLRQLEECRIMSSAKRPWLN
WENPDIMSELLFTNNEIIFKNGDADLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSI
GDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWLKDKNRGEAYDRAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAY
LRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPN
>A0A671SJ15|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPSAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYTMPLEAGSLE
SLIDKHEDVIKITMHYDQSQVSSVNLVCITELMDQALKKWQTTHGPEEDIGFRSDYVLRV
SGKLEFLFEDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIGSVIARKTSN
PPLLLPPKKRLPTASTLIVCHVRAGLFHGTELLCKTAVSSESSSRSEHVWNKTLEFDIAV
CDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHYPIAWVNTMVFDYRGQ
LKTGDIILHYELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVFPVFDKILEKAAE
IAGASDSMTMGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLL
LSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVYCLRDMSDDELLQ
YLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMFMPAVSVHFALILEA
YCRGCIPHIEVLKKQVEALSKLKAVNELIKFGTIKTKTKQAHLKEAMMTCLRQTGFIETL
SDLHSPLNPNILLAGINVERCKYMDSKMKPLWIVYNNKLLEGETVGIIFKNGDDLRQDML
TLQILRLMDLLWKEANLDLRIVPYGCLATGDHAGLIEVVSSADTIANIQKTSSNMAAAAA
FNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFH
IDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRK
NGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTT
KVNWMAHIVAHPS
>H3CN55|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tetraodon nigroviridis|TrEMBL
IQLSDEDLQGVPADHSRRRRRKKAISSASRSSMDQISVEFVLPSGARGKSGSDKLLLDVA
ANWTVEQVKTQVWLRAVTLNVCPDFYQRFSPDQCILLYQKKGSVCEIYDKQQVFQTLDCV
CYWKALKKDVGRIQLVLRPQQLDESRQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLT
PRRIELADRDPKLYSMDPWVTGKPLPEHLLSKVSNGYILAVIHIGTVSQTIKVCIQDSPA
QVLASFFAKTSNKRVLLGIPENVCEADFVLRVCGREEYLYGDKPLQDFNWIRQCLKNGED
IHLVLESPPNPDLDLVQKEDWAQVDDCTGAAGTHEQLTIDGKDHERVFTISMWDCNRRFR
VKVLGIDIPSLPKIPDFVVFVEASIFHGQQLLAQERTSSKTFTEEVLWNCWLEFNIKIKD
LPKGARLSLQVVCRKQAQTPNSKDSAASPGSHDGKAKSRLLYYVNLLLVDHRSLLRQGEF
ILHMWKMPEKSEESGSGSVNADKLTSATNPDRVSSMAIAVLLDKYCCPVVLPKSRAARGG
GEEAAGGERGRREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECTRDPRAYPKLL
SSVRWGRQEDVSETHRLLERSSAWDSSRLDVGLALQLLDCHFSDAQVRSMAVRKLETLED
DDVLRYLLQLVQAVKFEPYHDSSLVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRF
AVLLEAYLRGCGEDMLQDFRKQVEITEALQKVTREIKAVSAEKYDITAQVVFQLRQKLEA
LQSSGLPEDFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADGSTLSKDPIGIIFK
DGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQ
SVVGSTGAFKDEILCQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIM
ITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPNFQKFQNVC
VKAYLTLRHHTNLLIILFSHFLFAGMPQLTSKEDIEYIREALTVGRSEDEARHLLDQIEI
CREKGWMVQINWFVHLVLGIKQGVEKRSI
>A0A851IUJ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Donacobius atricapilla|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPVAKGLGS
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQRPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKAA
SKPPPLPKKKPNHGTLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
WEVAVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGVIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A851J1C5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Donacobius atricapilla|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQVWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSISAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3B5LFG1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xiphophorus couchianus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
NFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDGINDQEVKDFRSKMFRLSEEKMQRVQMMTCNEWLQACFSPQLEPA
ALTTITDGLNDRPADLKVIIHFDQSQDSTSLKVLSSSTPSELMEMAVKKWLITHAPEEEE
WSGQYVLRVSHCLEFLCGDHPLIQYKYIRTCLQAKEPPHLTLVHTSTIKELFDKEMSAIS
AVVSRKSSNPPLPLPPKRRIPTVSPVQLWTIVLSFQIVLVKGSKVNAEESAKVQVRAGLF
HGTELLCKPAVSSETSGRSEHTWRDNALEFDISISDLPRMTRLCFAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSPYPIVFPPFDKILEKAAQIARASDSMSIGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLCPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAERNRKIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALT
KLKSVNELIKLGTLKNARSKTKEAMLTKEAMITCLKQSGYSEALSDLSSPLNPSVLLSDI
SVEKCRYMDSKMKPLWIVYNNKLLNGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAN
LDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTNSNVAATAAFNKDALLNWLKERNSG
DALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEDAYLILRKNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A663F4N8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aquila chrysaetos chrysaetos|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMV
AKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAL
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3B4ZUT5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Stegastes partitus|TrEMBL
MDGQQIQVSDEEPEVLREENRRRRRRKKAITSSSCSSMDQISVEFVLPTAARGGNGPDSL
LLEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQ
TLDCIRYWRALKKDVGRIQLVPRPQPSDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRRIELSDRDPNLYSMDPWVTRKPLPEHLHAKINNSHILVVIHISTASQTIKVSI
DDTPTQVLASFFAKTTNKRVLLGIPEHMCETDFVLRVCGREEYLYGEKPLQDFNWVRQCL
KNGEEIHLVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDC
NRKFRVKVLGIDIPSLPKVPEFIVFIEASIFHGQQLLAQERTTSKSFNEEVLWNCWLEFN
IKIKDLPKGARLNLQVICGKQPQTPNSKGGSYQDNTAGTASLDGKTKSRLLYYVNLLLID
HRSLLRQGEFILHMWKMPEKSDESSSSTNADKLTSATNPDKASSMAIAILLDKYCYPVVL
PKSRDVSRDYGAVGEEAEGGERGQREMPNHLKKQFGAIVATDPLHPLSPEDKELLWHFRH
ECMRDPRAYPKLLGSVRWGRQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQV
RSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLR
SEIAQSMHYQQRYAVLLEAYLRGCGENMLQDFRKQVEMTEALQKVTREIKAISTEKSDVT
PQVVFQLRQKLETLQASGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADP
TTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIE
IVKDATTIANIQQSVVGSTGAFKDEILCQWLRDKCVSEDKFQQAVERFLYSCGGYCVATY
VLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGK
KSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRS
EDEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A803XUF1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Meleagris gallopavo|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQVNSIANPPKMA
VKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNVAS
HPVYYPSFEQLLELGRNGEQPRSQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYP
QALAKLLTITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKL
TDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALR
FGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQET
YLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDL
RQDMLTLQMIQLMDVLWKQEGLDLSDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
EKAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C7HCC2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPRPSSGELWGMHLMPPSIMVDCLLPNGMILTLECTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDAEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVSIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A401T832|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chiloscyllium punctatum|TrEMBL
ITPGMDQPKNDNDNDNPIVLREENRRRRRKMRANTTRTMQYYSLEQLAIEFVLPTRNKLN
NVHEKLSLEVAGNYTVEQLKAKVWVKAGGMSVCPDFYQKLSPDQFRLMYQKKGQWYEIYD
KHQVIQTLDCINYWKTLQRNNGKIHLAQKTKTSKESLQLQNDLNYLIGYDVTDVSNVHDD
ELEFTRRKLITPQLNEVASRDPRLYSMDPWIISKSLPEYLLNKICNNNIFIVIHRGTTSL
TIKVSIDETPQSILKNFFKKVANKKGLLEISENHNEEHFVLRVCGREDYIVGNNPIKDFH
WVRNCLKNGEEIHFVLDVPPDPAMDEVQKEEWPLVDDCTGVTGSHQQLTLEGRDHDKVFT
ISLWDCDRKFRVKIIGIDIPVLPRNTELTVFVEASILHGQQVLAQQRTLTKAFTEEVLWN
VWLEFDIKVKDLPRGARLNLQVYCGKAPVQSMKSTFQSQDDNAWDTKSKNHMLYYVNLLV
IDHRSLLRQGEYVLHMWKIPDKGEEQGTIEADKLTSATNPDKQNSMAICILLDRYNYPIT
LPRSCQSQDAELERVGHEMHSQLRKQFEEIISTDPLNPLSTEDKELLWHFRHECMRQPKA
YPKFLSSVKWGQQDVVLKTQQLLDKQEMWNSSPLDVGLAMQLLDCRFSDERVRALAVEKL
ETLDNSEVLRYLLQLVQVK
>A0A5F4VXG4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callithrix jacchus|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSAAASLSPMELIPIEFVLPTSQRNCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRAPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKYLMDIPESQSERDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKVPAESPSSESKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCYPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEML
QKVTLDIKSLSAEKYDVSSQVIAQLKQKLENLQNSHLPKSFRVPYDPGLKAGALAIEKCK
VMASKKKPLWLEFKCADPTALSKETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDL
CLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKSPTEEKFQ
AAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKER
VPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQL
TSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>F7F3S0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca mulatta|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>G3MWH3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos taurus|TrEMBL
MCFYFMMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISCIKQMLW
KQVTNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPEL
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHSLIQFQVHVRAGLFHGTELLCKTVVSSEISGKNDHIWNE
PLEFDINTCDLPRMTRLCFAVYAVLDKVKTKKSTKTMNPSKYQTIRKSGKVHYPVAWVNT
MVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIKFPENKKQPY
YYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQ
DCRENFPHALPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYA
VGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVH
IPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMH
TCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVI
FKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADI
QLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSD
NIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFR
QCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTEEEALKQFKQ
KFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3P9KC36|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MPPAMTDLVDIWAAHSPLDGQAPVHVTMDFLLPTGIYIQMEVPREATIQHIKLLLWKQAK
SFPLSSFLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVFRLVTRNCGRAERLLD
SKIGVIIGKGLHELDGINDQEVKDFRSKMQRLSEERMQRVQMMSFTEWLQACFSPQLEPS
AGTAIADGANDWPADLKVIIHFDQSQDSTSLKVPSSCTPSVLIEIALKKWQTTHAPEEET
NKDKHILRVSQCLDFLCGDHPLIQYKYIRSCLQAKESPHLTLVHINAVKAIFDKENAAIG
AVVSRKSSNPPLPLPPKKRAPTQVQTCVWDVSRPFKVVLVKGSTVNADENAKVQVRAGLF
HGTELLCKPAVSSESSGRSNHSLENNTLEFEISVCDLPRMTRLCFAIYAIMEKVKKKSYK
NPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDMILHCWSSFPDELEEMLNPIGT
VRINPYPENATALHIHFPDYGPHPIVFPPFDKILEKAAEIAGSSDSTPIGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRLDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVSCLRDMSDEELLQYLLQLVQVLRYEPYYDCALTH
FLLERAQKNRKIGHFLFWHLRSEIHMPAVSIQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNTRSKTKEAMLTKEAMITCLKQSGYSEALSDLHSPLNPNVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLMSSDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLVLRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKSDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>H2ML76|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MPPAMTDLVDIWAAHSPLDGQAPVHVTMDFLLPTGIYIQMEVPREATIQHIKLLLWKQAK
SFPLSSFLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVFRLVTRNCGRAERLLD
SKIGVIIGKGLHELDGINDQEVKDFRSKMQRLSEERMQRVQMMSFTEWLQACFSPQLEPS
AGTAIADGANDWPADLKVIIHFDQSQDSTSLKVPSSCTPSVLIEIALKKWQTTHAPEEET
NKDKHILRVSQCLDFLCGDHPLIQYKYIRSCLQAKESPHLTLVHINAVKTIFDKENAAIG
AVVSRKSSNPPLPLPPKKRAPTVQVRAGLFHGTELLCKPAVSSESSGRSNHSLENNTLEF
EISVCDLPRMTRLCFAIYAIMEKVKKKSYKNPHINKYQTIRKAGKVHYPIAWVNTMVFDY
KGQLKTGDMILHCWSSFPDELEEMLNPIGTVRINPYPENATALHIHFPDYGPHPIVFPPF
DKILEKAAEIAGSSDSTPIGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRLDCREN
FPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVSCLR
DMSDEELLQYLLQLVQVLRYEPYYDCALTHFLLERAQKNRKIGHFLFWHLRSEIHMPAVS
IQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNTRSKTKEAMLTKEAM
ITCLKQSGYSEALSDLHSPLNPNVLLSDINVEKCRYMDSKMKPLWIVYNNKLMSSDTLGI
IFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIAN
IQLTSSNVAAAAAFNKDALLNWLKERNSGDALERAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSF
RQYCEEAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSDEEALKQFR
QKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7K6IUV5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Machaerirhynchus nigripectus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAAKRQQLSWAAWMECNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQARAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6J0U1V1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pogona vitticeps|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNIESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMTKESLYEQLPLD
TFTMPSYSRRISTATPYMNGEASVKSLWQINSNLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLQYEMHVLDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMSVIEDHANRTISRELGFNYGHAGLSNRLARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNMPEILPKLLLSVKWNSRDEVSQMYCLIKDWPYIKPEQAME
LLDCNYPDPMVRAFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDMLK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEVIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDPAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A6J0SNE2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pogona vitticeps|TrEMBL
MTLGIYCPVEFWSKETNQSIPVDFLLPTGIFLTLPISCHATLRTIKKVLWQHAQYEPLFH
MLSDPESYVFTCINQTAERQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQVSLL
IGKGLHEFDSLGDPEVNDFRTQMQQFCEERAARRQQLSWKAWMEYSFPVQLEPVANGLGK
KSPLQIPNKNLFVNVKFESGGESFTFQISPKEVPATLMSYAIKKQATIFRHQKVNSPEDY
ALQVNGKYEYLYGNYPLYQFQYVRHCLHRGLLPHLTMVHSSSILALWEEQTNGITSPPKA
GTRPPPVPKKKPTSVSLWSLEQPYYIDLIQGSKVNADERMKLVVQAGLYHGHEMLCKMVS
SPEVSVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKTKKARSTKKKSKKADCPIA
WVNVMLFDFQDQLKAGECSLPMWSSFPDDRGELLNPMGTVQTNPNTESAAALVIRFPSIS
SYPVYYPSFEQILEQGRNEPSPSYGLEDPEEMQQLREILERRSHTELYEHEKDLMWKMRQ
QIRDHYPGALAKLLVVTKWNKHEDVAQMIHLLQSWPELPVLSALELLDFSFPDRYVGSFT
VNSLKKLTDAELFQYLLQLVQVLKYESYFDCELTRFLLDRALSNRKIGHFLFWHLRSEMH
VPSVSIKFGLILEAYCRGSIHHMKALMKQIEALNKMKALSDIIKASAQKNTKPQTKEFMH
TCMRQETYLEALSNLQSPLNPSVILAKVSVDLCTFMDSKMKPLWIVFNNEEMGGSTVGVI
FKNGDDLRQDMLTLQMIQLMDILWKKEGLDLRMTPYGCLSTGDKTGLIEVVMNSDTIANI
QLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFR
GYCETAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKPEVARWGASPLPGGNP
>A0A7K8VYQ6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sclerurus mexicanus|TrEMBL
MELEDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTTNKHTKVPEIILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRLKIVGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNVWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIPSD
AQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKEKCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C5NGS4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
MPPGKYGMQEEWEKEGDQEILMDFLLPNGIFLNFLVSPNDTIKTIKKMVWKNARNEALFN
GLGDPEGYVFTCINQTAVREELEEESRRIRDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRSKMRSFCEEKAQKRQGLPWQQWMEYSFPCDLEPCSAKSKN
KKKIFINVKFEASDESFMLQQEPQDLPLALMRSALKKKATVFRSLRQEPEDYTLQVNGRW
EFIFGKHPLCQFKYIFSCLRNDENPQLTMVHHSTISKYQEEQGRMCNHIYRSCAMSRPPP
LPQKKQNTSSLWAINKPFNIHLLQGSRVNADEGMKLVVQAGLYHGSELLCKVVTSSEVTV
CSEPLWDQKLDFDINVADLPRMSRLCFALYAIIEKAKKPRGTKKKNKKADCPIAWVNTMV
FDHKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFPNILPHPLYY
PPLDKVLYTKLKEIMDNKNHTEFFEDEKELLWKLRTDIRDCYPESLSKLLLITKWNKRED
VVQMVSLLESWPELPAIHALELLDYSFPDPAIRSFTIRCLRKLSDDELLQYLIQLVQVLK
YESYLDCVLTTFLLERALANRRIGHFLFWYLRSEIHVASVSLRFGLILEAYCRGNIHHMK
VLTKQNQALVKMKALNDFVKSGSQKMTVEDLRLCVKQESYMEALSDLLSPLNPSVILAEI
CADKCRFMDSKMKPLWLMYRNPWPHADMLGIIFKNGDDLRQDMLTLQMIQLMENLWKKEG
LDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQLNSSTSAATAAFNKDALLNWLKSKNPE
DKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGI
NRERVPFILTYDFVHVIQQGKTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAG
LPELTSFKDIQYLKDSLALGKSEDEALKNFKVKFTEALRESWKTKVNWMMHSLAKDNRP
>A0A8C5EJS6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
MPPAMTDLLDIWAPHSPLAGHTLAQITVDFLLPTGIYIQMSVPREATIQHIKLLLWKQAQ
MFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRISEERMQQVQMMTCTEWLQACFSPQLEPA
ASAIISDGVSDRPTDLKVTIHFDQSQDSASLKVSWSCTSAELMELALRKWLSTHGPEEDA
CRGQYVLRVSHCLEFLCGDHPLIQYKYIRSCLQAKESPHLTLVHTRTIQAMFDKEISAIG
SVVSRKTSNPPLPLPPKRRVPTQVQTCVWDVSSPFKIVLVKGSKVNAEESAKVQVRAGLF
HGTELLCKPSVSSESNFRSDHTWKDSTLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKST
KNAHINKYQTIRRAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYLSHPIIFPPFDKILEKAAEIARASDCVSIGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQVLLQI
WPKLSPRDALELLDFNYPDQYVREYAVGCLRDISDEELLQYLLQLVQVLRYEPYYDCALT
HFLIERAHGNRVIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALS
KLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSIQLSGI
NVERCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAN
LDLRVVPYGCLATGDRAGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSG
DALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGYTEKFCNFRQNCEDAYLILRKNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKSDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7L2JRI2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cinclus mexicanus|TrEMBL
MEVRDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIVLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEDVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFLIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKSQGPSKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRSG
DYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSDP
QGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVKW
GQQDIVAKTYQLLAKKEAWDQSALDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVLH
YLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILE
AYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGSK
LPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDL
RQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGN
TGAFKDEILNQWLKERCMIEEKFQEAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETG
NLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTYGKKTSLHFHKFQDVCVKAYL
ALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDK
GWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6A4T9C4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MILTLECLREATLITIKHELFKEARKYPLHHLLQEETSYIFVSVTQEAEREEFYDETKRL
CDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPEVQDFRRNILNVCKD
SVELRDASGPHSRALYVYPPNIESTPDLPKHIYSKLDKGQIIVVIWVIVSPNNDKQKYTL
KINHDCVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQGKYILKVCGCDEYLLEKYAISQ
YKYIRSCIMLGRMPNLMLMAKDSLYTQLPTDNFVMPSYSRRISTATSYMNGEGAAKSLWA
INGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQMCDNVNTQRVPCSNPRWNEWLTY
DMYIPDVPCAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTHVLVANKMALNLWPVP
HGLEDLLNPIGVTGSNPNKETPCLELEFDHFSSQVKYPEMNAVEDHANWIISRELGFNYN
LSGQSNRVARDHALTDSDTEQLRQLSNRDPLSEITEQEKDFLWRHRHYCMNIPEILPKIL
LAVKWNSRDEVAQMYCLLKEWPSIRPEQAMELLDCNYPDPVVRHFAVRCLDKYLTDDKLS
QYLIQLVQVLKYEQYLDNPLARFLLKKALTNQKIGHFFFWHLKSEMHNKTVSQRFGLLLE
AYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKIQCKGGLKGALQFNSNTLHQ
WLKDKNKGEMYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLD
HKKKKFGYKRERVPFVLTQDFLIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFI
NLFSMMLGSGMPELQSFDDIAYIRKTLALEKSEQGKGLYPDRLTGRLIVL
>A0A673G9K2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVEMRDASGPHSQIIVVIWVIVSPNNDKQKY
TLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLKMCVQEYQGKYILKVCGCDEYLLEKYPI
SQYKYVRSCIMLGRLPNLISTISSLPCQSLTRFYVSFSTIKTKKIESNREIKTQPYYLQC
FNSACFINEHLNDLLQEHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGV
TGSNPNKETPCLELEFDHFSSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDH
AMTEADIEQLRQLSNRDPLSEITEQEKDFLWRHRQYCVNIPEVLPKILLAVKWNSRDEVA
QMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVRLI
YSVIDYKCPYCVYFRIGYIYNVCKAKIYTESEMHNKTVSQRFGLLLESYCRACGMYLKHL
SRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLG
NLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMEN
IWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLK
DKNKGEMYDMAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKK
KKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINL
FSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHT
IRHHAQN
>A0A444V2C4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acipenser ruthenus|TrEMBL
MDSIFQETQFFKDDDDIADLKTIGQGNTLTFDCVLPTKKANHDANEIIAVKVNSQANVRQ
LRLHIWIQAKEKSSHPEIYHITDPESYQLLYKKGEEWYEIYDDYQILKTLDSVRYWGLQG
MNKGTIIVKANPKDTEDRLRFEKDLSYMIGHDISMALENRLDEFSFARRKLASIRRLEIR
NRDYWAYATEPWASSTPIPKDLEAMLNYEVATTVHYNGMSHKFKADIKEPPTSLIKSFLN
MMAENGIPVGHAESGFVLKVCGREEYLTGDRPLSDFLWIRQCLKTKQEIQLSVLPTPTLQ
EDEVLVEDWPLVEDYTGLANTHEELDLENKDINQILMISLWDCNQKFRVKLLGIDIPELP
SKVPPNVYIEASILHGRTVLSSVQSKPMPFTDEVLWNVWLEFDFLLKNVPRGARLVFTVN
GIVNEGNTMREARSQPQGTKTADYKGKARTLYFVNLLLIDHRSLLCQGEHILHMWPFPEK
EEDLFTYDADKMSSKTNPDTANSMAISIIMDSYRFPVVLPHSRASNPSCINPTSSDLSSE
ENSLPTPGLTNKDLLRGFTEVCSQYGVSLPKFLSTINWGDPTAVQDIHWLVSHWNPVDLD
ISIALELLSIHFADEHIRRMSIKRLERLHNDELLRYLLQLVQALKVEPYHDSILARFLIK
RALQSKRIGHFFFWYLRSEITASPYFRDRFAVILEAYLLGCGQSMLEGFLKQVQVVESLQ
KVVIDIKKIIPEKSDLPANAALKLQEMLRSISLPKDFLVPYDPRIRAGEIMVEKCKVMAS
KKKPLWLEFNSSDSEGASGSTIAIIFKHGDDLRQDMLVLKTMAIMDSIWQGSSLDLNLIP
YGCISTGYNIGMIEVVRDAMTIASVQRSKGGTTGAFKNDALFEWIREKCQVEEITMAIMD
SIWQGSSLDLNLIPYGCISTGYNIGMIEVVRDAMTIASVQRSKGGTTGAFKNDALFEWIR
EKCQVEEIEICIRAYLDLRSNSNLLITLFSLMMLTGIPELSSTDDIKYLKEALQLGKDDS
SAQEHFLNQISICENQGWTVQANWWIHMVAGIK
>A0A444U640|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acipenser ruthenus|TrEMBL
MPPAMTDILDIWAVDSHLVNDACITVDFLLPTGIFIQMDVPREATLQHIKLLLWKQAQSY
PLFTFLGQMEAYMFECVNQAAVHEELEDESRRLCDVRPFLPALKLVTRNCGRAEKLLDSK
IGVLISKGLHELDALQDPEVKEFRAKMLRISEEWMEWLQCSFCPLLEPSVPDNILDKLHG
GQIVIAVRFDNSQIVSLKVSPHTSPSALTEQALRKWLTTHGKEEEEANSNNFVLRVSGRL
EYLFGDHPLIQFKYIRNCVTNNESPHLTLIDSCTVKEVFEKELSTIGAVVNRKSSNPPLP
LPPKRRATSQISTCVWDVMVPFTIVLVKGSKVNAEETVKVQVRAGLFHGTELLCKPAVSA
ETFGKNEHVWDKTLEFEINVCDLPRMTRLCFAVYAVMDKVKKQKSTKNIHAKYQTIRKAG
KVHYPIAWVNTMVFDYRGQMKTGEIILHSWSSFPDELEEMLNPIGTVQTNPYTENATALH
IKFPAYSRSTVFYPPFDKILEKAAQIARNSDCVTMAGRGGKKFHIELKEIMERDPLYQLC
ENEKDLIWTLRYDCRENFPQSLPKLLLSVKWNKHEDMAQLQALLQIWPKLSPRDALELLD
FNYPDHDEELSQYLLQLVQVLRYEPYYDCALSRFLLERAQANRRIGHFLFWHLRSEIHMP
AVSVQFALILEAYCRGSIPHIEVLKRQVEALTKLKAVNELIKLGTIKNTKSKAKEAMMTC
LKQSAYTETLSNLQSPLNPSVILSGLNVEKCRFMDSKMKPLWIVYENKLLGGESLGIIIK
NGDDLRQDMLTLQILRLMDMLWKEANLDLRIVPYGCLATGDKSGLIEVVSASETIANIQL
TNSNVAATAAFNKDALLNWLKEKNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRQVSF
WFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEDALKQ
FRQKFDEALRESWTTKVNWMAHNVAKDNRSAPAPTQGPLSGSANPETGGPPPPPNTTSNR
RIQQSQAQVDEVVDVMRMNMEKVMERDTKLSELDDRADALQAGASQFETSAAKLKRKNWW
KNCKMMIILGGVCAIILIIIISKYI
>A0A673IL60|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSAELPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKITHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDERHQA
>A0A093BGT1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chaetura pelagica|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELIPIEVILPTSNKHTEVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDISNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCSRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIRI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHDSPNTDSKCKIQLLYYVNLLLIDHRFLLRT
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIVQLRQKLEKLQSS
KLPGSFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADQTALSSETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDICVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A0A0ATP7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Charadrius vociferus|TrEMBL
MELGDDEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQMTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K6PWN4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ifrita kowaldi|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEILLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAVSIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A093C9H0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pterocles gutturalis|TrEMBL
SRMPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGL
GTGPLQTPTRNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPED
YTLQVNGKCEYLYGNYPLFQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPK
MAAKPPPLPKKKPNCGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVITA
PKGASFFALQDCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPN
TESAAALVICFPSVASHPVYYPSFEQVGDTGHTVVSGSRLSPVYALSCDSHEQKLQLKEI
LERRSHTELYEHEKDLVWKMRHNIRDQFPQALAKLLIITKWNKHEDVAQMISLLQTWPEL
PVLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLL
DRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKA
LNDFVKVSSQKATKPQTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDS
KMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGC
LSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILT
YDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDI
QYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNR
>A0A669AY85|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKSKNIKKIFINVKFEASDESFMLQQDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTITKYQEEQGRMCSQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPSVPGTFQPCLFLHFPPLQKIKKTPPPQHFELKEIMDN
KNYTEFFEDEKELLWKLRTEVRDHYPESLSKLLLITKWNKREDVVQMVNLLRNWPDLPAI
HALELLDYSFPDPAVRSFTIRCLRKLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLERA
LSNRRIGHFLFWHLRSETHVASVGLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSD
FVKLGSQKVTAEDLKQCIRQESYLEALSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWL
MFKNPAVEGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKM
GLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGY
CVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVI
QQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSL
ALGKTEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A669D3P1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPFHQLLVF
LSCHDFMLQQDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQVNGRWDFIYGKHPLCQ
FKYIFSCLRNGQNPHLTMVHYSTITKYQEEQGRMCSQVYKMLKSSASKPHVLPPSNHYCV
SVVPLQLVVQAGLFHGSELLCKVVTSSEVTVSSEPLWNQKLEFDINVADLPRMSRLCFAL
YGVIEKTKKPRGTKKKNKKAPDGRKDCPIAWVNTMVFDYKDQLKTGEFHLSTWPDLLNPM
GTVEKNPNVDSAAELLIHFPNIRTHMWQILHSYNFCFLKEIMDNKNYTEFFEDEKELLWK
LRTEVRDHYPESLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAVR
SFTIRCLRKLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRS
ETHVASVGLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQ
CIRQESYLEALSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIF
KNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQ
RNSSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDN
IMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRE
YCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVK
FNEALRESWKTKVNWMMHSLAKDNRP
>A0A3R7MRK8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Trypanosoma rangeli|TrEMBL
MSSSSAFFDAGEVDFREDLEADDIYGSENSEEFERLFEKSKQAKRNVTLLSTTLQTLIFE
QNDIGTEAEIEAIVEYVLGAAPHGYGGSVEAREFRRELIASFEYEWHKFQRENPNVSLSQ
AMRILPYRFILLPMEKTQLEMLTELNSRKMGSGELGIVLLRIWYIDLAGCTCSTLRGFPL
DMKASEAILITMERLFSITNFDNSKHQGLTHVFKVQGRREYVYGDEILINFRYIRECVTQ
QLEINVLVEPHEKTFLNDPIFVPLYSYPSKFSGEHCANIYGGDTSEDVSAGMSVWNIHEK
LGIQFEGSLCNLVFSLERAKEEGVRAGDTLYLAMLVEVYYGAKVVCPPQMTNWVMCNELV
ASSETNSFSSVKWGNKNKLTFDILLSDAPRELKLCITLMATCGERLGAVTSLSAEDIVQK
AKERFGVRKPDEYHMRPVFFLGIASVQLFNYLTYMQTGKLEMRLWGTRKKANPMCPIPSN
LNKNDMGVSLVFPTFDKPVLIPNVAPPTTKRHDWEQQFFASELCLDENLRESNIEQLKQL
KRILASDPLTELTASDKVLLWKHREELLMRPRALSKFLLAVNWLQPYAAYEAHSLLKRWT
PPEPMDVLELLDIRFVDLVVREYAVKYLNGMTDYELKGCVLQLVQVLKHEPYHDSALFRF
LLKRSLQSPNMIGHYVFWYLVSEMGNTSVSERYGLLLEELICRMPERRGYLHQLYVADQL
FESAMRVKDAPKKDRIDHLRGHLKGLRLPRRFTLPLNPAMECCGLDIGKCKVMDSKKSPL
WLVFRNFQEECEPFYVIFKAGDDLRQDVLTLQLLELMDSLWKSCGLYLHIIPYGCIATGE
GVGMIEVVLNSDTVANITRKYGGAQAAFREEPLMNWLRQFNRERDEVERCLCNFICSVAG
YTVATYVLGIGDRHNDNIMLRQDGTLFHIDFGHFLGNFKRKFGIKRETAPFIFTPMYVYM
LGGQSSPIYVYFVDLACHAYNVVRRVGGTLMTLFMLMLSTGIPELQNVEDISWLRTVLRI
DSSNEEAKEHYKQQISLAMANFRALFNDYIHIVTH
>A0A671WHM2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MDGKQIQVSDEEPRVVREETRRRRRKKAITSSSCSSMDQITVEFVLPTTARGGNSPDTVL
LDVAGNWTVEQVKAQVWLKAVTLNLCHDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTRKLLPDHLLSKVSNNHILVVIHIGTVSQTIKVSID
DPPAQVLASFFAKTANKRVLLGIPDDMCEEDFVLRVCGREEYLYGEKPLHNFNWIRQCLK
NGEEIHLVLESPPDPELDQVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVNTPLYLSHPGGKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMP
EKSEESSSSINADKLTSATNPDKASAMAIAILLDKYCYPVVLPKSRDVGRDVGAGGEEAE
GGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRW
GKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLR
YLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLE
AYLRGCGEDMLQDFRKQVEMTEALQKVTREVKAMSADKYDITAQVVFQLRQKLENLQSSG
LPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDL
RQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGS
TGAFKDEILYQWLRDKCVSEDKFQQAVEKFLYSCGGYCVATYVLGIGDRHNDNIMITESG
NLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQVQKM
>A0A5F8H8Q0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodelphis domestica|TrEMBL
MPPGVDCPMEFWSKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVARQGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAAHRQQLGWEAWMHYNFPLQLEPSSHGWGA
GTLRAPNRNLFVNVKFEGNEESFTFQVSPNDLPLALMACALKKRATVFRQSGLERPEDYT
LQVNGKYEYLYGNHPLFQFQYICHCLHKGLTPHLTMVHSSSILAMRDEQSNPPAQAPKLR
AKPPPIPVKKPSSVSLWSLEQPFCIELVQGSKVNADERMKLVVLAGLFHGNEMLCKTVSS
SEVTVCSEPVWRQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWSSVPDEKGELLNPMGTVRSNPNTESAAALVICIPEVAP
HPVYYPTLEKILELGKNGEHARFTEDEQQQLREILERKVAGELYEHEKDLVWKMRREIQE
QFPEALARLLLVTKWNRHEDVAQMLFLLRSWPELPVLSALELLDFSFPDRHVGSFAIQSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSNHHMKVLMKQGEALNKMKALNDFVKVSSQKTTKPQTKELMHVCMR
QETYLEALSNVQSPLNPSTLLSEVCVEQCTFMDSKMKPLWIVYSNEEAAGGADSHVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVSHSDTIANIQ
LNKSNMAATAAFNRTPCSLAQSXLSFPCLELL
>A0A1A8MK57|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius pienaari|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLDCLRETPLISIKQQLFVEARKFPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDSEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIVSPTNSKQKYTLKVSHDSLPEQLIAESIRKKTRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIVVGRLPHLMLVSKDSLYSQLPAS
GYITPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYINVNIRDIDKIYVRT
GIYHGGEPMCDNVNTQRVPCSHPRWNEWLTYDLYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYSYCHGLSSRLACDSTVSASDAEQLRSLCSKDP
LYELSEQEKDFLWRHRHYCINIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMESESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKVQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEGYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQTFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A6Q2Z788|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPVEYGMLGEWEKEGDLEIMMDFLLPTGIFLKFSVSHNDTIGAIKKMVWSNASNEPLYG
ALSDMDAYVFTCINSTAEREELEDETRRLCDVRPFMPVLRLVAREGDRVEKLTNTQISLL
IGKGRNYYYYSLHKLMKIVNEFRAKMRSFCEERALERQQLPWYQWMEYSFPCELEPCVLL
AEPGGIKTKCKKIFVNVKFEASDESFMLQHEPQDLPVTLMRSALKKKATVFRSVHQEKPE
DYTLQVNGRWEFIYGKYPLCQFKYIFSCMRGGQTPHLTMVHHTTIVKYQEEQGRLASQVS
RCRSLSKPPPLPLKKNTSSLWSIEEPFNIHLIQGNRVNADEGMKLMVQAGLFHGSEMLCK
VVTSGEVNVCSEPLWDQKLVFDINVSDLPRMSRLCFALYAVIEKNKKPRSTKKKNKKADC
PLAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNIDSAPGLLIRFP
NIRPYPLYYPPLEKMSELERKGEKLKATKEEHMKLMEIVDNKNYTEFFEDDKELLWNLRG
VVRQRYPESLSKLLLITKWNKREDVAQMVDLLHKWPELPALHALELLDYCFPDPRVRSFT
IRCLRKLSDEELLQYLLQLVQVLKYESYLDCDLTTFLLERALANKRIGHFLFWHLRSEMH
VSSVSLRFGLILEAYCRGNICHIKSLWKQNEALNKMKAVNDFVKSGWQKTSRQQMTDDMK
LCIKQEAYIWALSNLLSPLNPSIILSEICADRCKFMDSKMKPLWLMYKNKCVQGEAAGII
FKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSETIANI
QRNNSNSAATAAFNKDALLNWLKSKNPEDKLDNAIEEFTLSCAGYCVATYVLGIGDRHND
NIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFR
AYCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKV
KFNEALRESWKTKVNWMMHSLAKDSRL
>A0A6Q2XMI3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPVEYGMLGEWEKEGDLEIMMDFLLPTGIFLKFSVSHNDTIGAIKKMVWSNASNEPLYG
ALSDMDAYVFTCINSTAEREELEDETRRLCDVRPFMPVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRAKMRSFCEERALERQQLPWYQWMEYSFPCELEPCVLLAEP
GGIKTKCKKIFVNVKFEASDESFMLQHEPQDLPVTLMRSALKKKATVFRSVHQEKPEDYT
LQVNGRWEFIYGKYPLCQFKYIFSCMRGGQTPHLTMVHHTTIVKYQEEQGRLASQVSRCR
SLSKPPPLPLKKQNTSSLWSIEEPFNIHLIQGNRVNADEGMKLMVQAGLFHGSEMLCKVV
TSGEVNVCSEPLWDQKLVFDINVSDLPRMSRLCFALYAVIEKNKKPRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNIDSAPGLLIRFPNI
RPYPLYYPPLEKMSELERKGEKLKATKEEHMKLMEIVDNKNYTEFFEDDKELLWNLRGVV
RQRYPESLSKLLLITKWNKREDVAQMVDLLHKWPELPALHALELLDYCFPDPRVRSFTIR
CLRKLSDEELLQYLLQLVQVLKYESYLDCDLTTFLLERALANKRIGHFLFWHLRSEMHVS
SVSLRFGLILEAYCRGNICHIKSLWKQNEALNKMKAVNDFVKSGWQKTSRQQMTDDMKLC
IKQEAYIWALSNLLSPLNPSIILSEICADRCKFMDSKMKPLWLMYKNKCVQGEAAGIIFK
NGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSETIANIQR
NNSNSAATAAFNKDALLNWLKSKNPEDKLDNAIEEFTLSCAGYCVATYVLGIGDRHNDNI
MIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRAY
CEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKF
NEALRESWKTKVNWMMHSLAKDSRL
>A0A2K5E2J8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aotus nancymaae|TrEMBL
MLNGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRTKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHFSSILAMRDEQSNPAPQVQKPR
TKPPPIPAKKPSSVSLWSLDQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISISDLPRMARLCFALYAVIEKARKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
YPVYYPPLEKILELGRHSECVRVTEEEQLQLREILERRGCGELYEHEKDLLWKLRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLGALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEASSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A1A8FLF7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius korthausae|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLDCLRETPLISIKQQLFVEARKFPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDSEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKTRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIVVGRLPHLMLVSKDSLYSQLPAS
GYITPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYINVNIRDIDKIYVRT
GIYHGGEPMCDNVNTQRVPCSNPRWNEWLTYDLYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYSYCHGLSSRLACDSTVSASDAEQLRSLCSKDP
LYELSEQEKDFLWRHRHYCINIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMESESAL
ELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKVQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEGYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQTFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A8C3X0G1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Catagonus wagneri|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3Q3BBK1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Kryptolebias marmoratus|TrEMBL
MPPGKYGMQEEWEKEGGQEINMDFLLPTGIFLKFPVSRNETIRNIKKMVWKNARSEALYC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNAQISLL
IGKGLHEFEAQKNHEVDEFRNKMRTFCEEKAQERQSLPWQQWMEYSFPCDLEPCGSPPLY
GSVKSKNTKKLFVNVKFEACEESFMLQQDPQDLPVALMKSALKKRATVFRSVRLEPEDYT
LQVNGTMEFLYGNHPLRQFKYIFSCLRNGQNPQLIMVHHSTIIKYQEEQGRLCSQACKTR
SLSRPPPLPMKKLVVQAGLFHGSELLCKVVTSSEVTVCSEPLWNQRLEFDMNVSDLPRMS
RLCFALYAVIEKTKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDD
KSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPLDKVLSPERNGDAVSTTKEEV
HQLKEIMDNKNYTEFFEDEKELLWKLRTEVRDYYPESLSKLLLITKWNKREDVVQMVSLL
KHWPDLPAIHALELLDYSFPDPAVRSFTVRCLRKLSDDELLQYLIQLVQVLKYESYLDCD
LITFLLERALSNRRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIFHIKLLSRQNEA
LGKMKALSDIVKSGSQKMMVDDLKLCIRQESYKEALSDLLSPLNPSVILSEICADKCRFM
DSKMKPLWLIYRNGTEQGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRDKLD
QAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRER
VPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPEL
TSSKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A8D0C421|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salvator merianae|TrEMBL
MPPGIYCPVEFWSKEANRNIQVDFLLPTGIYLNLLVPCSATLSTIKKAVWHHAQYEPLFH
MLSDPDSYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSSGDPEVNDFRAKIHQFCAERAAQRQQLSWRAWMEYSFPVQLEPLAGSPER
KNSLRIPNKNIFVNVKFESGGESFTFHISPKELPMTLMSYAVKKQATVFRHQRINSPEDY
TLQVNGKCEYLYGNYPLYQFQYIHDCLHHGLLPHLTMVHSSSIMALWEEQANGIAHSPKS
VARPPPIPKKKPTSASLWSFDQPYYIDLVQGSKVNADERMKLVVQAGLYHGNEMLCKMVS
SSEVSVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIA
WVNVMLFDYKDQLKTGECSLPMWSSFPDEKGELLNPMGTVQTNPNTESAAALVIHFPSLS
AYPLLTEEEPLWEILERRSHAELYEHEKDLLWKMRYQIRDHYPGALAKLLVVTKWNKHED
VAQVSSLMVHLLQSWRELPVLNALELLDFNFPDRCVSSFTVNSLKKLTDVELLQYLLQLV
QVLKYESYLDCDLTKFLLDRALSNRKIGHFLFWHLRSEMHVPSVAIKFGLILEAYCRGSP
YHMKALMKQSEALSKMKALNDIVKLSSQKISKLQTKEYMHACMRQETYMEALSNIQSPLN
PHIILSKVSVELCTFMDSKMKPLWIVFSNKNMGGSNMGLIFKNGDDLRQDMLTLQMIHLM
DILWKKEGLDLRMTPYGCLSTGDKMGLIEAVMDSDTIANIQLNKSNMAATAAFNKDALLN
WLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLG
NFKTKFGINRERVPFILTYDFVHVVQQGKTNNSEKFERFRDYCERAYMILRSHGLLFLHL
FALMKAAGLPELSCSKDIQYLKDSLALGKTDEEARKHFQLKFNEALRESWKTKVNWLAHN
VSKDNRQ
>A0A8C3PA28|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysemys picta bellii|TrEMBL
MPPAMTDILDIWAVDSQIGADGLISVDFLLPTGTYINLDVPRDATICHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVCEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVKEFRSKMRRISEEKLLSLVGLSWVDWLKHSYPPEQEPSVPE
NFQDKLYGGNLVVAIHFDKCQDVFSFQVSPNINPVKLNELAIRKRLTIHGKDNEVDPSDY
VLQISGRLEYIFGDHPLIQFQYIRKCVMNRTLPHLTLVECCSIKKMCEQEMIAIEAAINR
KSSNLPLPLPPKKTRTVTQLTQSVWDISNPFKIMLLKGNKLNTEETAKVHVRAGLFHGTE
LLCKPIVSPEISGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKTINP
SKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDLLLHSWTSFPDELEEMLNPMGTVRTN
PYTENATALHIKFQEYSKLPIYYPPFDKILEKAAEIAKSSENAGMAGRGGKKFYIELKEI
MERDPLTQLCENEMDLIWTLRYDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWSKL
PPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLV
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGVILEAYCRGSIAHMKVLSKQVEALNKLKT
LNSIIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELYVEKCKYMDS
KMKPLWIVYNNKMFGGDLLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGC
LATGDHSGLIEAVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRMGFTCMVRRTTKERSTDKEENTWDSRRTWDSSQ
>A0A812DX62|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sepia pharaonis|TrEMBL
MPDVSAKVKPNGEISLDFLMPNGILIPMSVDFYCSTFEKIKQDLWLESVNFPLYNLLRHC
DTYTFLFVNSRGQKEEVLSESQSLSEIKPSVTFLKLIEKEPNSERCYSFDRRITSLIGAP
IVDLTDYQSLEVSDFKLRIKYETEKIIQERDLMGWEERMRYLYPLRLINDQLLNKISLKL
KHGSGCIDVCREQKSFKEIVDMNSTPKSLIIHLLKKFSNLWKLPDTDPSNFMLKVKGYEE
YLYGDYCLLHFKYIYECLQKDIIPSIFLVTRSEIVIPAPVVPPHRRLAPPLLSPSPSRVG
SQKSSIYSWNISSNVNIFVKSVSQVQTTESRVKLVTGLYHGPDILCAAAKTEETLLYDQS
CTWNSNLNFDHLIKDLPEMTRVCFMLMAVGGVKKKQKDTTPLAWVNISLFDFRSQLRQGE
YELYMWSVTEDESIPEEESCFPIGTVTPNPAGKNATTLTIGQYSLHPCNIFFLPFFVSLS
LSLSPSPFLCLPLPFFVSSPFFVSSPFFVSLSPFLLPLPLISIYPHSFLPKF
>A0A4W5QSY1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHEVFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKCPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGESSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMTTVEGHANWTISRELGFNYCQSGQSNRVARDHALTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNIRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCMS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDLAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFER
>A0A2U4B9A2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tursiops truncatus|TrEMBL
MPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKQTYPPEHEPSIPE
NLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDEVSPYDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAIEAAINR
NSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKAINPSKYQ
TIRKSGKVDYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALA
NRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLKTLNSLI
KLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYIEKCKYMDSKMKPL
WLVYNNKVFDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDHSGLIEVVSTSET
IADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGD
RHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKF
GRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALK
QFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C7SJE4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRTKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVV
TSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPHFDKPTSYICNHYTCNHLLKEIVDNKNYTEFFEDEKELLWKLRGVVRERYPE
SLSKLLLITKWNKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLR
DEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRF
GLILEAYCRGNIYHIKSLCKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAY
MEALSYLLSPLNPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDTVGIIFKNGDDLR
QDMLTLQMIQLMEILWKKEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMI
KETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCE
QAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNE
ALRESWKTKVNWMMHSLAKDSRL
>A0A8C9RHC4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MAPGVYCLPNMWEGGVQQVKMDFLLPTGIYLSFGVSGNDTIGAIKKTLWRNAKNEPLFFA
LSDPDAYVFTCINHTAEQEELEDEQRRLCDVRPMMPILRLVAREGDRVEKLITSQISLLI
GKGVHEFDTMKNHEVNEFRTKMRTFCEELAMDRQRLPWQKWIEYSFPCDLEPCALLSHSG
NLRNRASKKIIVNVKFEASDESFTLQVEPQEVPLTLMKSALKKKATVFRPMKQEKPEDYA
LQVNGRWEFIYGNFPLCQFKYIFNCLHSGVTPHLTMVHYSTITKYQEEQGGISREISKNR
SSSKPPPLPLKKTMSSLWSIQDAFSIHLMHGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SSEVNVCSEPVWDQKLEFDINVCDLPRMTRLCFALYAVIEKSKKPRSTKKKNKKADCPLS
WVNTMVFDYKDQLKTGEYYLSTWPSVPGNSLGLEKMFQANKMSMSTNANQNSYLSVVLPH
HSVFFCYMGMWLRQVHCVQYQSLSEIVENKNYTEFFEDDKEILWKLRYEVREKYSESLSK
LLLITKWNKHEDVAQMVSLLQKWPDLPALHALELLDYSFPDRNVRSFTIRCLRKLSDDEL
FQYLLQLVQVLKYESYLDCDLTKFLLERALSNKKIGHFLFWHLRSEMHVPSVNLRFGLIL
EAYCRGSIYHMKTLMKQNEALNKMKSLNDFVKSASQKGTRTQTTGEMKKCIKQETFMEAL
SDLLSPLNPSLILSEICPDRCKYMDSKMKPLWLVYKNEKVQGDPLGIIFKNGDDLRQDML
TLQMIQLMEILWKKEGLDLRDKLEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENG
QLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYK
ILCRNGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRE
SWKTKVNWMVHSVSKDNR
>A0A8B9QE09|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Apteryx owenii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWSINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A5C6NC22|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu flavidus|TrEMBL
MDAEQAQLSDEDSAIVTGDHSRRRRRRRKAVSSAPHSSMDQISVEFVLPAAARCKSGSDK
LLLDVAANWTVEQVKTQVWLRAVTLNICPDFYQRFSPDQCILLYQKKGSVCEIYDKHQVF
QTLDCVCYWRALKKEVGRIQLVLRPQPSEESLQYQRYLNYLIGYDVTDVSNVHDDELEFT
RRKLLTPRRLELMERDPKLYSMDPWVTCKNLPEHLLSKVSNGSILVVIHVSTVSQTIKVS
IDDSPAQVLTSFFAKTSSKRVLLGIPENLSETDFVLRVCGREEYLYGDKPLQNFNWVRQC
LKNGEEIHLVLETPPNPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDGKDHERVFTISMWD
CNRKFRVKVLGIDIPSLPKIPDFLVFVEASIFHGQQLLAQERTSSKTFTEEVLWNCWLEF
NIKIKDLPKGARLSLQVVCRKQPQTLNSKGGSAQQDGPAAAAAAAGGHDGKTKSRLLYYV
NLLLVDHRSLLRQGEFILHMWKMPEKSDESSSSINADKLTSATNPDRASSMAVAILLDKY
CYPVVLPKSRAASREARGGVEEAQGGERGQREMPNHLRKQFAVIVRTDPLHPLSPEDKEL
LWHFRHECTRDPRAYPKLLSSVSWGKQEDVLETHRLLERSSAWDSSGLDVGLAMQLLDCH
FSDAQVRSLAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSSLVRFLLKRALRSKRIGHF
LFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRKQVETTEALQKVTREIKTVSA
DKYDITAQVVFQLRQKLEALQSSGLPQDFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQ
FKRADSTTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGN
RIGMIEIVKDATTIANIQQSVVGSTGAFKDEILCQWLRDKCVNEDKFQQAVERFLHSCGG
YCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYV
MGTSGKKSSPNFQKFQNVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREA
LTVGRSEDEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRSA
>A0A5C6P3R6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu flavidus|TrEMBL
MPPRPSSGELWGMHLMPPSILVECLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDCNGPHSRALYVYPPNVESSPELPRH
IYNKLDKGQIIVVIWVIVSPTNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
IFTIPSYARRISTATPYMNGETATKALWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLSYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEHF
GCPVKYPDMTIIEEHANWNISRELGFNYCHTGLSSRLARDNPVTDADNDQLRQVCTRDPL
SEITEQEKDFLWRHRQDCLNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIRPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A7K6UVD0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Notiomystis cincta|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVLNSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPSTLMSYAIKKQATVFRHETVQKAEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSS
SEVSVCSEPVWKQRLDFDINICDLPRMARLCLALYAVIEKARKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEPPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
SSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P3RIK5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pteropus vampyrus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQFEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLSLMACALRKKATVFRQSLVEQPEDYA
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHCSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIQLIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVNVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEELQLREILERRASGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELAKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPQTKELLHLCMRQ
ETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSEGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A672ZVQ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
GKLEHRKYDEEPVVLREENRRRRRKKAITSSSCTSMDQIAVEFVLPTAARGGNSPDTLQL
EVAGNWTVEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTL
DCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTQRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVCNGFILVVIHISTASQTIKVSIDD
TPAQVLSSFFTKTANKRVLLGIPENTGEKDFVLRVCGRYKEYLYGDKPLQNFNWIRQCLK
NGDEIHLVLETPSDPEADLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPELVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIRDLPKGARLNLQVNSICCLSGKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKS
EESSSSSINADKLTSATNPDKASSMAITILLDKYCYPVVLPKSRDVCRDGGTWGEEAEGG
ERGQREMPNHLKKQFEAIVATDPLHPLSPEDKELLWHFRHECMRHPRAYPKLLGSVRWGK
QDDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYL
LQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAY
LRGCGEAMLQDFRKQVEMTEALQKVTREIKAMSADKYDVTAQVVFQLRQKLETLQLSGLP
ESFRVPYDPGLRAGTLLIEQCKVMASKKKPLWLQFKRADPSTLSKDPIGIIFKDGDDLRQ
DMLILQILLIMESIWETESLDLCLLPYGCISTGNRIG
>A0A670ZS09|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pseudonaja textilis|TrEMBL
MPPRPSSGELWGMHLMPPKILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVELRAANAPHSRALYVCPPNIESSDLPKHI
YNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLKL
CVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMTKESLYAQLPLDT
FAMPSYSRRISTATPYMNGEASAKSLWAINSHLRIKILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLQYEMLVHDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFS
SPVKFPDMSVIEEHANWIISREQGFNYNHAGLSNRIARDNELRDNDKEQLRAICTRDPLS
EITEQEKDFLWSHRHYCVSMPEILPKLLLSVKWNSRDEVAQMYCLIKDWPQIRPEQAMEL
LDCNYPDPMVRAFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQ
RIGHFFFWHLKSEMHNKNVSQRFGLLLDSYCRACGMYLKHLSRQVEAMEKLINLTDILKQ
EKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLWL
NWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSI
GDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDPAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAY
IRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8B9TUC5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GLLHTPTKNIFVNVKFQSGGESFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANTPKMS
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPNVAS
HPVYYPSFEQLLELGRNGEPPRTQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYP
QALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFITNCSKYL
LQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYC
RGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCMKQETYLEALSHLQ
SPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIFKNGDDLRQDMLTLQM
IQLMDVLWKQEGLDLSDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFH
IDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRR
HGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKT
KVNWLAHNVSKDNRQ
>A0A7N6BME2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
VEEQIQVSDEEPVVLREEIRRRRRKKAITSSSSISMDQITVEFVLPTATWGSNPDSLQLE
VAGNWTVEQVKAQVWLKAVTSNLCPEFYQRFSPDHCILLYQKKGNLCEIYDKHQVFQTLD
CIRYWRALKKDVGKIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKL
LTPRRIELCDRDPKLYSMDPWVTRKPLPEHLLSKVCVKIDLKVFPKKTPISHLIFYPRLV
LASFFNKTANKRVLLGIPDNVCETDYVLRVCGREEYLYGDKPLQNFNWIRQCLKNGEEIH
LVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVK
VLGIDIPTLPKVPEFVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKIKDLP
KGARLSLQVVCGKQPQTPNSKGSSYQDNTTKSRLLYYVNLLLIDHRSLLRQGEFILHMWK
MPEKSEESSSSINADKLTSATNPDKESSMAIAILLDKYCYPVVLPKSRDVGRDVGAVGEE
SEGGERGQREMPNHLKKQFEAIVTTDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSV
KWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDV
LRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVL
LEAYLRGCGEAMLQDFRKQVEMTEALQKVTREIKTMSADKYDVTAQVVFQLRQKLEILQS
SGLPDNFRVPYDPGLRAGALMIEQCKVMASKKKPLWLQFKKADPTTLSKDPIGIIFKDGD
DLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVV
GSTGAFKDEILYQWLRDKCVSEEKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITE
SGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKA
YLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICR
EKGWMVQINWFVHLVLGIKQGVEKRST
>A0A8C3KDE8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calidris pygmaea|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMTKGLGA
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGDQPRQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQ
ALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYGDCEQDNELFQYL
LQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYC
RGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHVCMKQETYLEALSHLQ
SPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQM
IQLMDILWKQEGLDLSDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFH
IDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRR
HGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKT
KVNWLAHNVSKDNRQ
>A0A672R8T3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MEHHASDDEPPVVRREENKRRRRKMKAFTSTSAVSTDHIAVEFVLPTTNKNSRNLDTLHI
DVTGNWTVEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVVRTQPTEDSLQYQQFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDPKLYSMDPWMTTKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFAKITNKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKN
CEEIHLVLERPPDPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTFKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVLCGKAQTQTSKENECKNKSRLLYYVNLLMVDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDQYCYPVALPKSKDSPDSEMEGERG
QREMPNHMRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEA
VTITHRLLERSTVWDRSSLDVGLALQLLDCHFSDENVRTMTVRKLETLAGDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRG
CGEAMLQDFRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDSF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFMGISKERVPFVLTPDFLYVMSTTGKKSSTHFLQFQSICLKAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQ
FNWFLHLVLGIKQGVEKRSA
>A0A556U5K0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bagarius yarrelli|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLVTIKHELFKEARKFPLHH
LLQEEASYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESSPELPKH
IFGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMD
TFTMPSYSRRISTATPYMNGEASSKSLWTINSNLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLMYDMYIHDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SCPVKFPDKATIEDHAIKMLSRETGYNYFQSGQSSRQARDHHIMESDLEQLRQIANRDPL
SEITEQEKDFLWRHRQYCKAIPEILPKILLAVKWNARDEVAQMYCLLKGWPQIKPEQAME
LLDCNYPDPMIREFAVQCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLGRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDLAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A8C2NU62|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Capra hircus|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASLNSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPRLYAMHPWVTSKPLPEYLLKKITNNCVFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIA
KIQQSTVGNTGAFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHN
DNIMISETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKF
QDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFL
DQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A7L1J707|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Smutsornis africanus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSSELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLK
>A0A8C2NX13|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Capra hircus|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASLNSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPRLYAMHPWVTSKPLPEYLLKKITNNCVFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLRDFTQQVQVIDML
QKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLPQSFRVPYDPGLKAGALVIEKCK
VMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDL
CLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLSHWLKEKCPIEEKFQ
AAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKER
VPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQL
TSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A672I685|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salarias fasciatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSSVKYPDMNAVEDHANWTISREMGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRYRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKIMFSFICKFMYRCGCECMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIM
SSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLR
MLPYGCLSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDM
AVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERV
PFVLTQDFLIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPE
LQSFDDIAYIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A7N9AYH9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSRNDTIKLVWKNARSEALFTALGD
PDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFEAQKNHEVNEFRTRMRQFCEEKSQERQMLPWQQWMEYSFPCDLEPCCSLPSTKSRN
TKKIFINIKFEACDESFMLQQDPQDLPVALMKSALKKKATVFRSVRLEPEDYTLQVNGSW
DFIYGKHPLRQFKYIFSCLRNGQNPHLIMVHRSTISKHQEEQERMCNQVYKSRSQSRPPP
LPLKKNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSSEVTVC
SEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVNTMVF
DYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYP
PLEKVLTPYMVGLLRNWPDLPAIHALELLDYSFPDPAVRFFTIRCLKKLSDNELLQYLIQ
LVQVLKYESYLDCDLTTFLLERALANRRIGHFLFWYLRSEIHVASVSLRFGLILEAYCRG
NIHHIKLLTKQNEALGKMKILSDIVKSGSQKMTVDDLKLCIRQESYLEALSDLLSPLNPS
IILAEICAHKCRFMDSKMKPLWLMYGNPWAQGEMVGIIFKNGDDLRQDMLTLQMIQLMEN
LWKKEGLDLRMSPYGCLSTGNKMGLIEAVKNSDTIANIQRNSSNSAATAAFNKDALLNWL
KSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRENGQLFHIDFGHFLGNF
KRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGMLFVNLFA
MMKAAGLPELSSFKDIQYLKVCNNADYYDNAAATNEVDDNVDFLVSCFKKGLLSFGQIRG
>A0A7N8XRX8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSRNDTIKLVWKNARSEALFTALGD
PDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFEAQKNHEVNEFRTRMRQFCEEKSQERQMLPWQQWMEYSFPCDLEPCCSLPSTKSRN
TKKIFINIKFEACDESFMLQQDPQDLPVALMKSALKKKATVFRSVRLEPEDYTLQVNGSW
DFIYGKHPLRQFKYIFSCLRNGQNPHLIMVHRSTISKHQEEQERMCNQVYKSRSQSRPPP
LPLKKNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSSEVTVC
SEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVNTMVF
DYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYP
PLEKISDMERNDDTVTATKEEHQKLKEIMDNKNYTEFFEDEKELLWKLRYEVCSLYPESL
SKLLLITKWNKREDVVQMVGLLRNWPDLPAIHALELLDYSFPDPAVRFFTIRCLKKLSDN
ELLQYLIQLVQVLKYESYLDCDLTTFLLERALANRRIGHFLFWYLRLDTFAFWADPGSLL
LKLLDDLKLCIRQESYLEALSDLLSPLNPSIILAEICAHKCRFMDSKMKPLWLMYGNPWA
QGEMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRDKLDQAIEEFTLSCAGYCVA
TYVLGIGDRHNDNIMIRENGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQG
RTNNSEKFERFREYCERAYKILCRNGMLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALG
KSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A6I9KE44|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysochloris asiatica|TrEMBL
MPPGVDCPMEFWTKEETQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAALRRQQLGWEAWLQYSFPLQLEPAARGWGA
GTLRIPNRVLLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVERPEDYT
LQVNGKQEYLYGSYPLCQFQYVCSCLHSGLTPHLTMVHSSSILAMRDEQSNPTSQVQKPR
SKPPPIPVKKPSSLSLWFLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVSVCSGPVWNQRLEFDINICDLPRMARLCLALYAVIEKARKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
HPVYYPALEKILELGRHVEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHQVQE
LFPEALARLLLVTKWNKHEDVAQMIYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPAV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFIKVSSQKTTKPQTKELMHVCMR
QETYLEALSHLQSPLDPSTLLADVCVEQCTFMDSKMKPLWIMYSNEEAGSEGSVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVTKDNRQ
>A0A2D0T592|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ictalurus punctatus|TrEMBL
MEQHVSDDESPVVRRGDTRRRRRKMKAFTSNSSTAMDHLALEFVLPTTNKTTKNPDTLRL
DVIGNWTVEQVKAQLWLRAVTTNVCPEFYQKYSPDHCILLYQKKGSWYEIYDKHQVFQTL
DCIRYWKALKKEVGKIYLVLRPQPSEESIQYQKFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTTRKIELADRDPKLYSMDPWITTKPLPDYMLSKVANNNILIVIHKDTSSQTIKVSIDD
TPFQVLQSFFIKTTNKRALLGIPEDADESDFVLRVCGRDEYLFGNYPIKDFHWIRQSLKT
GEEIHLVLESPPDPEQDVVPKEDWSQVDDCTGVAGTHEQLTINEKDHEKVFTVSLWDCNR
KFRVKILGIDIPVLPRNSDLIIFVEASIFHGQQLLAQERTSSKPFTEEVLWNTWLDFNIK
IKDLPKGARLNLQVSCGKAQTQTSKDSASHDCKNKNRLLYYVNLLVVDHRSLLRQGEFIL
HMWKMPEKSEDNSSVNADKLTSATNPDKTSSMAIAVLLDKYCYPVALPKSRDSRDAPEME
GERGKKREMPNHLRKQFDQIVATDPLHPLSVEDKELLWHFAHECVRHPTAYPKFLGSVKW
GKQEAVMATHRLLERSTAWDQSPLDVGLAMQLLDCHFSDANVRTMAVRKLETLGDDDVLR
YLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILE
AYLRGCGDEMLQDFRKQVEITEALQKVTREVKAISAEKYDVSAQVVFQMRQKLESLQMQG
LPESFKVPYDPGLRAGSLVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDL
RQDMLILQILLIMESIWETESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGN
TGAFKDEILNQWLRDKCLNEDKYQQAVERFVYSCGGYCVATYVLGIGDRHNDNIMITESG
NLFHIDFGHILGNYKSFLGITKERVPFVLTPDFLYVMSTTGKKTSQNFLLFQNICVKAYL
ALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGCTEDVAQRHFLDQIEICRDK
GWTVQFNWFLHLVLGIKQGVEKRSA
>F1RIH5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPGVDCPMEFWTKEENQSVDVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKVSQRLALPLPSSPSSPCRRPTREPIGQHSGPGAGPGPLTQAPWLVHVKSR
AFEHLWPTGPVCGGGALRPPLSSQDLLPARLAEFHSLGSSEVSGPSGTCAAGLPVTAGVV
GSTELYRKPAKPPPTPPAMTTGLVTGASLLRIPLLQWPCFSVHLHTQPSSVSLWSLEQPF
CIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSVCSDPVWKQRLEFDINVCD
LPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWP
SVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAPHPVYYPSLDKILELGRHGEHGRF
TEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNRHEDVAQ
MLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYES
YLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLM
KQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDPSILLAE
VCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQ
EGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKN
PGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKF
GINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYAILRRHGLLFLHLFALMRA
AGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNR
Q
>A0A8D0PRW7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPGVDCPMEFWTKEENQSVDVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSDPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNRHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRYSEMHVPS
VALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCM
RQETYLEALSHLQSPLDPSPAPDGCAPGSVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGI
IFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLREALDRAIEEFTLSCAGYCVATYVLGIG
DRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEK
FERFRGYCERAYAILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEAL
KHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P8UHD0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gymnodraco acuticeps|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAIDLRDCNGPHSRALYVYPPNVESSVELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNSQRVPCSNPRWNEWLNYEMYIPDIPCAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGMEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMTIIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPTIKPEQAME
LLDCNFPDPMVRDFAVKCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A6P8V8N0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gymnodraco acuticeps|TrEMBL
MDGQQTQVSDEEPKVLREEPRRRRRKKAITSSSGSSMDQTSVEFILPTVVRGGSSPDSLL
LEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWKALKKEVGRIQLLPLPQPSDESLQYQRYLNYLIAYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKVLPERLLNKVSNGNILLVIHIGTASQTIKVSIS
DTPAQVLLSFFAKTASKKALLGIPEDTCEADFVLRVCGREEYLYGDTSLQDFNWVRQCLK
NGEEIHLALEDAPDPDLDLVQKENWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPELIVFIEASIFHGQQLLAQERTSSKNFNEEVLWNCWLEFNI
KIRDLPKGARLNLQVICGKRPLTPTSKGTLSYQDTAASTGSHEGKTKSRLLYYVNLLLID
HRSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASAMAIAILLDKYCYPVVL
PKSRDVCRDGGGGGEEAEGERGQREMPNHLKKQFAAIVNTDPLHPLSPEDKELLWHFRTE
CMRDPRAYPKLLASVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQMLDCHYSDAQVR
SMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKKALRSKRIGHFLFWFLRS
EIAQSMHYQQRYAVLLEAFLRGCGQEMLQDFRKQVEMTEALQKVTREMKAMYADKYDITA
QVVFQLRQKLETLQSAGSLKSFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPT
TLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVCEDKFQQAVEKFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGFSKEWVPFVLTPDFLYVMGTSGKK
SSPHFLKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSE
EEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A3Q2W4C5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Haplochromis burtoni|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVRLSVCVYLSAPTPDDSPVSLPVCLSGVWLR
>A0A851LKE3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Corythaeola cristata|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSTLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITEA
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDICVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A2I3GXF8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nomascus leucogenys|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMHKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6G0HFS0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Larimichthys crocea|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKLIEPLGNREEKILNREIGFA
IGMPVCEFEMLKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKD
SLYSQLPASGFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIR
DIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSV
KGRKGAKEEHCPLAWGNVNLFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKE
TPCVELEFSWFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDAEQ
LRSLCSRDPLYELSEQEKDFLWRHR
>A0A6G0IIH5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Larimichthys crocea|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSTDLPKH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHEYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMTIIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDTEQLRQVCNRDPL
SEITEQEKDFVWRHRQDCVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8B9W6R5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus grunniens|TrEMBL
MCFYFMMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISCIKQMLW
KQVTNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPEL
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHSLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMVAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEPLEFDINTCDLPRMTRLCFAVYAVLDKVKTKKSTKTM
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPHALPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKTEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A0S7GKF9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poeciliopsis prolifica|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRNASGPHSRALYVYPPNVESTQELPKH
IHSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLTRMPNLMLMAKDSLYTQLPTE
>A0A852H4A7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Larus smithsonianus|TrEMBL
KMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLY
QLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGF
AIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSSELPK
HIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQL
KLCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPL
DTFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTG
IYHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEH
CPLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDW
FSNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDP
LSEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAM
ELLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDIL
KQEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGD
>A0A3R7NTW2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Trypanosoma conorhini|TrEMBL
MSSSGAFLEAGEVSFKEELEEDDIYGFENSEEFERVFAKSKKSKRSVTQLSTTLQALIFQ
NNGIDAEAEFEAIVEYILGAGSHSYGGSLEAREYRRALLASFEYEWQEFQQEHPSVSLAQ
AMRILPYRFTLPPMEKTQLEMLTDLNPRKMGSGNLGTVLLRIWYIDLAGCTCSTLRGFPF
DMKASEAILTTMERLFSITNFDKSKRQGLTHVFKIQGRREYVYGDEILINFRYIRDSVTQ
QREINVVVEPHEKTVLTYPVFVPSYSYPSNSSGKHRAGINRSDAPDGVSAGISVWDIHGK
LGIKIKGRLCNLVFTSERAKEEGVREGDSLYLAMLVEVYYGAKLVCPPQMTNWVICNDLV
GSSELNGFSSVTWGKKTKLAFDIQLSNAPRELKLCITLLATCGDRFGAVNSLSAEELVQK
AEDHSGLKRTDEYHVSPVFFLGVASVQLFDYLSYMQTGKVNLRLWGTKKKANPMCLIPNN
LNKNDMLFSLTFPTFNKPVLIPNAAPPDSKRNEWEHRLLESELCLHENLRESKIEQLKQL
KRILASDPLTELTTSDKVLLWKHREELIMRPRALAKFLLAVNWLQPYAVYEAHSLLKRWA
PLQPMDVLELLDIRFVDILVREHAVKYLNGMTDYELKGCVLQLVQVLKHEPYHDSTLSRF
LLKRSLQSPNMIGHYVFWYLVSEMGNTSVSERYGILLEELIRRMPERRGYLHQLYVADQL
FESAMRVKEAPKRDRIDCLREHLKSLSLPPRFTLPLNPAMECCGLDIGKCKVMDSKKFPL
WLVFRNFQEECEPFYVIFKAGDDLRQDLLTLQLLELMDSLWKSCGLYLHIIPYGCIATGE
GVGMIEVVPNSDTVANITRKYGGAQAAFRDEPLMNWLRQFNRERDEVERCLWNFICSVAG
YTVATYVLGIGDRHNDNIMLRQDGTLFHIDFGHFLGNFKTKFGIKRETAPFIFTPMYAYM
LGGQSSPIYVYFVDLACHAYNVLRRFGGTLMTLFMLMLSTGIPELQKVEDIGWLRTVLLI
DRSSEEATEHYKLQISLAMANFRALFNDYIHIVTH
>A0A8I3S5T6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNDFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPNDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKMRIISVHVRAGLFHGTELLCKTIVSSEISGKNDHIWNEPLE
FDINTCDLPRMARLCFAVYAVLDKVKTKKSTKNINPCKYQTIRKSGKVHYPVAWVNTMVF
DFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIKFPENKKQPYYYP
PFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQDCR
ENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGC
LRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVHIPA
VSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNKAKGKEAMHTCL
KQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKN
GDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLN
SSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIM
VKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCC
EDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFD
EALRESWTTKVNWMAHTVRKDYRS
>A0A091HXK2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calypte anna|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRTTTSVWDISNPFKIVLLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSSEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQSINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQMLRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A091UEY8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phoenicopterus ruber ruber|TrEMBL
SRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGI
GTGPLHTSTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPED
YTLQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPK
MAAKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYSVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQVGDMDAFFWEAQKFPSLAGAGAYSVTKLQLKEILERRSHTELYEHEKD
LVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPD
RYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFW
HLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKP
QTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETG
GGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMH
SDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGYVGLPFTQGCFTASFQLETFLLLCF
GYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVH
VIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKD
SLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNR
>A0A8C4E332|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAIEDHANWTISRELGFNFNLSGQSKRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A667H7N0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lynx canadensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C4DP43|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MTPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMLKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEGYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A834B0E8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phyllostomus discolor|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
SFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKVLCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSTRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A667XJV2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
YFLENSPVVLREESRRRRRKKAITPSSCASMDQITVEFVLPSAARGGSGPDTLLLEVAAN
WTVEQVKAQVWLRAVASNLCPDFYQRFSPDHCILLYQKKGSVCEIYDKHQVFQTLDCIRY
WRALKKEVGRIQLVPRPQPTDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPR
RIELSERDAKLYSTDPWLTDRPLTEHLLSKVSNGHILLVIHVGSNSQTIKVSIDDTPAQV
LASFFTKTANKKALLGIPDSVCEADFVLRVCGREEYLYGDKPVQNFHWIRQCLKNGEEIH
LVLETPPDPALDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVK
VLGIDIPSLPKNPELTVFVEASIFHGQQLLAQERTTSKPLSEEVLWNCWLEFNIRIRDLP
KGARLNLQVTAQKTQRELFSSAQTPNSKTKSRLLYYVNLLLVDHRSLLRQGEFILHMWKM
PEKSEESSSSVNADKLTSATNPDKASSMAVSVLLDRYCFPVVLPKSREAGRDAAAPDEAE
GGERGQREMPNHLRKQFEAIVATDPLHPLSPEDKELLWHFRHECMRHPRAYPKLLSSVRW
GKQEDVLITHRLLERSTAWDSSRLDVGLAMQLLDCHYSDAQVRSMAVRKLETLGDDDVLR
YLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIVQSMHYQQRYAVLLE
AYLRGCGEAMLQDFRKQVEVTEALQRVTREIKAMSADKYDVSAQVVFQLRQKLETLQSSG
LPDSFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSRDAIGIIFKDGDDL
RQDMLILQILLIMESIWETENLDLSLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGS
TGAFKDEILHQWLRDRCVSEDKKLCCVCVCVCVCVCVCVCVCVCVCAGNLFHIDFGHILG
NYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFHKFQFVGCDVCVCVCVCVCVCV
>A0A667X4G3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
IDEEPVVLREESRRRRRKKAITPSSCASMDQITVEFVLPSAARGGSGPDTLLLEVAANWT
VEQVKAQVWLRAVASNLCPDFYQRFSPDHCILLYQKKGSVCEIYDKHQVFQTLDCIRYWR
ALKKEVGRIQLVPRPQPTDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPRRI
ELSERDAKLYSTDPWLTDRPLTEHLLSKVSNGHILLVIHVGSNSQTIKVSIDDTPAQVLA
SFFTKTANKKALLGIPDSVCEADFVLRVCGREEYLYGDKPVQNFHWIRQCLKNGEEIHLV
LETPPDPALDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVL
GIDIPSLPKNPELTVFVEASIFHGQQLLAQERTTSKPLSEEVLWNCWLEFNIRIRDLPKG
ARLNLQVSCGKSAQTPNSKASSTKSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPEKSEE
SSSSVNADKLTSATNPDKASSMAVSVLLDRYCFPVVLPKSREAGRDAAAPDEAEGGERGQ
REMPNHLRKQFEAIVATDPLHPLSPEDKELLWHFRHECMRHPRAYPKLLSSVRWGKQEDV
LITHRLLERSTAWDSSRLDVGLAMQLLDCHYSDAQVRSMAVRKLETLGDDDVLRYLLQLV
QAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIVQSMHYQQRYAVLLEAYLRGC
GEAMLQDFRKQVEVTEALQRVTREIKAMSADKYDVSAQVVFQLRQKLETLQSSGLPDSFR
VPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSRDAIGIIFKDGDDLRQDMLI
LQILLIMESIWETENLDLSLLPYGCISTGNRIGQPARTHTHTHTHTHTHTYTHTHMHRLI
SVNLSVLRLQV
>A0A674BZT3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MVWRNASSEPLYGALSDADAYVFTCINSTAEREELEDETRRLCDVRPFMSVLRLVAREGD
RVEKLTNTQISLLIGKGLHEFDSQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSF
SCDLEPCVSLAEPGGIKTKGTKKIFVNVKFEASDVSQEPQDLPMILMRSALKKKATVFRS
VRQEKPEDYTLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTIVKYQEEQG
CLGSQVSKSRSLSKPPPLPVKKVRGQPLGTTLVVQAGLFHGSELLCKVVTSGEVNVCSEP
LWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPLAWVNTMVFDYK
DQLKTGEFLLSTWPSVPGDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPHFDKVH
LILKKWREGYSHQGGGKGLSILKEIVDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKL
LLITKWNKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLRSPQFI
DEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLKSEMHVSSVSLRF
GLILEAYCRGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAY
MEALSYLLSPLNPSIKLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIFKNGDDLR
QDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSA
ATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETG
QLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYK
ILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDSRL
>A0A7J6A5L2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ameiurus melas|TrEMBL
MPPGFNCDLQDVWEKEGREQVTMEFLLPTGIYLSFPVACSDTIANIKKMLWKNARSEPLF
CILSDPDAYVFTCINRTAEREDLEDEQRRLCEVRPFLPVFRLVAREGDRVEKLINTQISL
LLGKGLHEFDTQKNHEVNEFRTKMRSFCEEKAQERQRLPWHHWMEYNFPCDLEPISVVAQ
SGKLHTNVKKIFINVKFEASEESFMLQLDPQDLPLVLMKSALRKKATVFRPVKQEKPEDY
TLQVNGRWEFIYGKYPLFRFKYIFSCLYGGLTPHLTMVHHSTIAKYQEEQGGLSNQVSKS
RSQSKPPPLPLKKQNTSSLWSIQEPFYIHLLHGTRVNADESMKLVVQAGLFHGSELLCKV
VTSGEDCPLAWVNTMLFDYKDQLKTGDIFLSTWPSAPDDKGDLLNPMGTVEKNPNMDSSA
GLLIHFGTFKPHPLYYPPLEKLTEINGEKAHATKEENLKLKEIVDNKNHTEFFEDEKELL
WKLRGEVRAKYPESLSKLLLITKWNKHEEVAQIVALLRKWPDLPALHALELLDYSFPDPH
VRSFTIRCLRKLCDDELFQYLLQLVQVLKYEPYLDCDLTTFLLERALSNKRIGHFLFWHL
RSELHVPSVSLKFGLILEAYCRGSIYHMKSLMKQNEALSKMKALNDFVKSGSQKSASRSQ
ITEDMKLCIKQDTYLEALSGVVSPLNPSIILSEICTESCKFMDSKMKPLWLMYKNKCVQS
DTLGVIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMIPYGCLSTGNKTGLIEVVKNS
DTIANIQRNKSNSAATAAFNKDALLDWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGI
GDRHSDNIMIRENGQLFHIDFGHFLGNFKAKFGINRERVPFILTYDFVHVIQQGRTNNSE
KFERFRECCEQAYKILCRNGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGRSEEEA
LKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A226MDE6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callipepla squamata|TrEMBL
MEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYHMLSDPEAY
VFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHEF
DSVQDLEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPVTKGLGAGLLHTPIK
NIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYTLQVNGKYE
YLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINSIANPPKTAVKPPPLPK
KKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVNVCSE
PVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKAVSKANVRLSQACQS
CRAQDSILSQVPIAFR
>A0A2K5U222|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca fascicularis|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K4Q4B8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Melospiza melodia|TrEMBL
MPPGIYCPTEFWSKGENQSIQVDFLLPTGIYLNISVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRTKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPNKNIFVNIRFQSGGESFMFQISPWEFPIALMTCAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPYYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKMGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLVITKWNRHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A6P6GZT6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Puma concolor|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A2I0TTF6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Limosa lapponica baueri|TrEMBL
MQLRNQFPVKSKSSVSHPERGLWHFGERHKESCTLLASMIVAKWEIIFNLNSCVAALSAS
GSQEVSRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHA
QYEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVI
NSQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEP
MAKGLGTGPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPVTLMSYAIKKQATVFRHETV
ENPEDYTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSTIIAMRDEQTNCI
ASPPKMAPKPPPLPKKKPNYGSLWSLEQPFYVELVQGSKVNADERMKLVVQAGLFHGNEM
LCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKK
ADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVI
CFPSVASHPVYYPSFEQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAINSLKKLKDH
ELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRMTPYGCLSTGDKTG
LIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYC
VATYVLGIGDRHSDNIMIRETGQVWESLLL
>A0A3B4GWU3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pundamilia nyererei|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKVTADPVASLHLSQFVLHLTYLLPIVHMSR
TGQVRLSNVSLKCHPGLGDLQFLTCVSAVHPLLHHRGTSSSPDARVQRQPLLSASRLRLR
HAFLQVWPSRCHTCRYHRTGGDLSCVCFSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVR
LLCATYVNVNIRDIDKVSRYSLPGPAASHVGSNRCYHDQASALTQVTITCFEKL
>A0A8C5J3A9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Junco hyemalis|TrEMBL
MPPGIYCPTEFWSKGENQSIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPNKNIFVNIRFQSGGVNFMFQISPWEFPITLMSYAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKVRGDRDPWAPLLGTRWLVVQAGLFHGTEMLCKTVSSSEVSVCSEPVWRQRLE
FDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWANVMLFDYRDQLKTGE
CCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHPVYYPSFEAPVGWLS
PECALAVQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNRHE
DVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDDDVFQYLLQLVQVL
KYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPAVSLRFGLILEAYCRGSTHHM
KVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMWTDLVDQCTFMDSKMKPLWIVF
NSEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGL
IEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCV
ATYVLGIGDRHSDNIMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQ
GKTNNNEKFERFRGYCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLAL
GKTDEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C8BKB1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Otus sunia|TrEMBL
MLAGTCRMLLGEFWVMSLISSGMELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELI
SIEFILPTSNKHTKVPEMILLEIAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFIL
QYQKKGQWYEIYDKHQVLQTLDCILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLI
GYDVTDVSNVHDDELEFTRRRLVTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNN
NIFIIIHRGTTSQKIKVSIDDTPDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRD
EYITGETPIKDFHWIRQCLKNGEEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQ
LTIDGKDHERVFTISLWDCNRKFRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRR
TSSKPFTEEVLWNIWLEFDIKIKDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSK
CKTQLLYYVNLLLIDHRFLLRSGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMA
ISIVLDKYCHPIALPKHRITSDPQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELL
WHFRYESIKHPKAYPKLLSSVKWGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNF
SDENVRAMAVQKLESLDDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFL
FWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLHDFMKQVQVIESLHKVTMEIKSVSAE
KYDVTSQVIAQLRQKLEKLQSSNLPESFRVPYDPGLRAGTLVIEKCKVMASKKKPLWLEF
KCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNK
IGMIEIVKDATTIAKIQQSTVGNTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGY
CVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVM
GSSGKKTSLHFHKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDAL
TVGKSEEDAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K5QRY5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Prunella himalayana|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKEKCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0JNZ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|TrEMBL
MPPAMADNLDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRRKMRKFSEAKIQSLVGLSWIDWLKHTYPPEHEPSVLE
NLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEDEASPCDY
VLQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINRNSSNLPLPLPPKKTRVIS
HIWDNNNPFQITLVKGNKLNTEETVKVHVRAGLFHGTELLCKTVVSSEISGKNDHIWNEQ
LEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTM
VFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQTNPYAENATALHITFPENKKQPCY
YPPFDKIIEKAAELASGDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQD
CRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAV
GCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALDNRRIGQFLFWHLRSEVHT
PAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLSRAKGKEAMHT
CLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYSSRAFGEDSVGVIF
KNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQ
LNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDN
IMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQ
CCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQK
FDEALRESWTTKVNWMAHTVRKDYRS
>A0A2K6MH81|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinopithecus bieti|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRRQLSWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
TEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKCKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVHSNPNTDSAAALLICLPEVAP
HPVYYPTLEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>Q9EQL1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|TrEMBL
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLD
CLHYWKLMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIANNCIFIVIHRGTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMNISESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
DEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFAEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPSLSSKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRHGDY
VLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSXHYQQRFAVILEAY
LRGCGTAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSNLP
ESFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLVVMGSSGKKTSPHFQKFQDCCVSTLQYY
GDVCVRAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFL
DQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A665UL24|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
LSLCNHHLPPLQLCREEIRRRRRKKAITSSSGTSMDQITVEFILPTVARGGNSPDSLQLE
VAGNWTVEQVKAQLWLKAVTSNLCPDFYQRFSPDHCILLYQKKGNLYEIYDKHQVFQTLD
CIRYWRALKKDVGRIQLVPRPQPSDESLHYQRYLNYLIGYDVTDVSNVHDDELEFTRRKL
LTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVSNGHILVVIHIATASQTIKVSIDDT
PAQVLASFFTKTANKRVLLGIPENMCETDYVLRVCGREEYLYGDKPLQNFNWIRQCLKNG
EEIHLVLETPPDPNQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTVSMWDCNRK
FRVKVLGIDIPSLPKVPEFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNSWLEFNIKI
KDLPKGARLNLQVVCGKQPQTPNSKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSE
ESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKTEGGERGQREMPNHLKKQFA
AIVATDPLHPLSPEDKELLWHFRQECMRDPRAYPKLLSSVRWGKQEDVLTTHHLLERSSA
WDSSGLDVGLAMQMLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSA
LVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEAMLQDYKKQV
EMTEALQKVTREMKTMSADKYDVTAQVVFQLRQKLETLQLSGLPESFRVPYDPGLRAGGL
MIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWE
TESLDLCLLPYGCISTGNRIGRSRNWTGVERKRVQTAQLFCDV
>A0A1S3GMI7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dipodomys ordii|TrEMBL
MSPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHHAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRVKMRQFCEEAAVHRQQLGWEAWLQYSFPLQLEPSSRSWGA
GSPRTPNRTLLVNVKFEGSEESFTFQVSSKDKPVALMACALRKKATVFRQRLAERPEDYA
LRVNGKQEYLYGSHALCQFQVQKPRTKPPPIPAKKPSSVSLWSLEQAFCVELVQGSKVNA
DERMKLVVQAGLFHGSEMLCKTVSSSEVSVSSEPVWQQRLEFDISVCDLPRMARLCFALY
AVVEKTKKARSTKKKSKKADCPIAWANLMLFDYKNQLKTGEHCLYMWPSVPDEKGELLNP
VGTVRSNPNTESAATLLICLPEVSPHPVYYPALEKILELGRPGERMRATEEEQLQLREIL
ERRGSGELYEHEKDLVWKLRHEVLERFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELP
VLSALELLDFSFPDCHVGSFAIKSLRKLTDDELSHYLLQLVQVLKYESYLDCELTKFLLD
RALSNRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGCTHHMKVLMKQGEALSKLKAL
NDFVKVSSQKTTKPQTKELMHLCMRQDAYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSK
MKPLWIMYSNEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGC
LPTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILT
YDFVHVIQQGRTNNSEKFERFRGYCEKAYSILRRHGLLFLHLFALMRAAGLPELSCSKDI
QYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWMAHNVSKDNRQ
>H2SZ19|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
MPPAMTDLLDIWATHAPLAGHDPDQITMDFLLPTGIYIQCDVPRVATIKEIKQLLWKEAH
SFPMFSKLGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRGERLLD
SKIGVLIGKGLHELSAINDQEVKDFRSKMTRISEERMQTIERMTCTEWLQASYSSQLDVP
ADTTTMDGTDRPADLKIIIHFDQSLDSASLKMASTCTPRDLITQAVRKWLTTHGPEEDAL
RGQYVLRVSHCLEFLCGDHPLIQYKYIRTCMQAKEPPHVTLVHNNTIKTMFERDICAIRA
ALTPKSCSLPLPLPPKKRAPTQVQTCVWDVSSPFKIVLVNASKVNAEETAKVQVRAGLFH
GTELLCKPAVSSESSGRSDHAWKDTTLEFELPVCDLPRMTRLCFAIYAVMDKVKKQKSTK
NTHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGT
IQTNPYTENATALHISFPEYSSHPIIFPLFDKILEKAAEIAGASDCASMGRGGKKFHIEL
KEIMERDALSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PRLCPRDALELLDFNYPDQYVREYAVNCLRDMSNDELSQYLLQLVQVLRYEPYYDCALTH
FLLERAQSSRKIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALNK
LKAVNELIKLGTLKNARSKTKEAMLTKEAMMTCLRQTGFSETLSDLHSPLNPNILLSGIN
VEKCRYMDSKMKPLWIVYNNKLLVGDMLGIIFKNGDDLRQDMLTLQILRLMDRLWKEANL
DLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNMAAAAAFNKDALLNWLKERNSGD
ALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSNGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGQAEKFGSFRQYCEKAYLILRKNGNFFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKSDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C5FTQ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MPPRPSSGELWGMHLMPPRILVDCLLPNGMFLTLECLREATLITVKHELFKEARKHPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDTNGPHSRALYVYPPNVETSTELPKH
IFNKLDKGQIIVVIWVIVTPSNDKQKYTLKINHDYVPEQVIAEAIKKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
TFTMPSYARRISTATPYMNGETATKCLWAINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMASIEEHANWNISRELGYNYCHTSLSNRLARDNPLTDSDNEQLHLVCSRDPL
SEITEQEKDFLWRHRHYCFNIPDILPKLLLAVKWNSRDESAQMYCLLKDWPAIKPEQAME
LLDCNFPDPKIREFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEHMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKEDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEAVDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A1A7W7Z9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Iconisemion striatum|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLDCLRETPLISIKQQLFVEARKFPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKTRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIVVGRLPHLMLVSKDSLYSQLPAS
GYITPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPMCDNVNTQRVPCSNPRWNEWLTYDLYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYSYCHGLSARLACDSTVSASDAEQLRSLCSKDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMESESAL
ELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKVQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEGYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQTFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A674HML5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGV
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGRTPHLTMVHSSAIIAMRDEQTNGITSPPKAA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKAGLFHGTEMLCKTVSSSEVS
VCSEPVWRQRLDFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAWVNVM
LFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHPVY
YPSFEQLLELGRNGEQPRAAPEDSEEKLQLREILERRSHTELYEHEKDLVWKMRYDIRDQ
YPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAVNSLK
KLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPAVA
LRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCMKQ
ETYREALSHLQNPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGD
DLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKS
NMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVR
ETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCER
AYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFNEA
LRESWKTKVNWLAHNVSKDNRQ
>A0A8C4ZAT4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Atlantic cod|TrEMBL
HPYENYKHDNYNHGDREEPQRGSRTRRRRKGITSASLSAMDQITIEFILPTTPKNGLSPH
TTLLEVPGNWTVEQVKAQVWLRAVASNFSPDFYHKFSPDHCILLYMKKGTLCEIYDKHQV
FQTLDCIRYWRALKKDVGRISLVFRPPQQDEALRYQRFLNQLIGYDVTDVSNVHDDELEF
TRRKLLTPRRNELQERDPRLYAVDPWLTDRPLRDHLLSKVMNGHLLVVIHIFTTSQTIKV
SIDSTPEQVLASVFAKTANKRALVGIPDDVCESDFVLRVCGRYEYLYGDRPLQDFSWIRR
CLKNGEEIHLVLEKLPDTDLDQVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMW
DCNRKFRVKVLGIDIPLLPRNPDLTVYIEASIFHGQQLLAQERTTSKPFMEEVLWNTWLE
FDIKIRDLPKGARLNLQVGSKSKTRLQYYVNLLLVDHRSLLRQGEFVLHMWKIPEKGEES
SSSVNADKLTSATNPDKASSMAVAVSLDKYCYPVVLPKKDSGEPGGERGQREMPNHLRKQ
FEAILAKDPLHPLSPEDKELLWHFRHECMRHPRAYPKLLASVRWGRQEDVQAAHAMLERS
SAWDSSGLDVGLALQMLDCNYSDAQVRSMAVRKLETLGGDDVLRYLLQLVQAVKFEPYHD
SALVRFLLKRALRSKRIGHFLFWFLRSEIVQSLHYQQRYAVLLEAYLRGCGDAMLTDFHK
QVEVTEALQKVTREMKAMLADKYDVSSQVVFQLRQTLEALQSSGLPQTFRVPYDPGLRAG
TLMIEQCKVMASKKRPLWLQFKRADPSSLSSDPIGIIFKDGDDLRQDMLILQILLIMESI
WETESLDLYLLPYGCISTGNRIGMIEIVKDAATIANIQQSVVGSRGAFKDEILNQWLRDK
CVNEDRFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKS
FMGISKEWVPFVLTPDFLYVMGTAGKKSSPHFQKFQDVCVKAYLALRHHTNQLIILFSMM
LMTGMPQLTSKEDIDYIREALTVGRSEEEAERHLLEQIEICREKGWMVQINWFVHLVLGI
KQGVEKRST
>A0A8C4ZAT4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
HPYENYKHDNYNHGDREEPQRGSRTRRRRKGITSASLSAMDQITIEFILPTTPKNGLSPH
TTLLEVPGNWTVEQVKAQVWLRAVASNFSPDFYHKFSPDHCILLYMKKGTLCEIYDKHQV
FQTLDCIRYWRALKKDVGRISLVFRPPQQDEALRYQRFLNQLIGYDVTDVSNVHDDELEF
TRRKLLTPRRNELQERDPRLYAVDPWLTDRPLRDHLLSKVMNGHLLVVIHIFTTSQTIKV
SIDSTPEQVLASVFAKTANKRALVGIPDDVCESDFVLRVCGRYEYLYGDRPLQDFSWIRR
CLKNGEEIHLVLEKLPDTDLDQVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMW
DCNRKFRVKVLGIDIPLLPRNPDLTVYIEASIFHGQQLLAQERTTSKPFMEEVLWNTWLE
FDIKIRDLPKGARLNLQVGSKSKTRLQYYVNLLLVDHRSLLRQGEFVLHMWKIPEKGEES
SSSVNADKLTSATNPDKASSMAVAVSLDKYCYPVVLPKKDSGEPGGERGQREMPNHLRKQ
FEAILAKDPLHPLSPEDKELLWHFRHECMRHPRAYPKLLASVRWGRQEDVQAAHAMLERS
SAWDSSGLDVGLALQMLDCNYSDAQVRSMAVRKLETLGGDDVLRYLLQLVQAVKFEPYHD
SALVRFLLKRALRSKRIGHFLFWFLRSEIVQSLHYQQRYAVLLEAYLRGCGDAMLTDFHK
QVEVTEALQKVTREMKAMLADKYDVSSQVVFQLRQTLEALQSSGLPQTFRVPYDPGLRAG
TLMIEQCKVMASKKRPLWLQFKRADPSSLSSDPIGIIFKDGDDLRQDMLILQILLIMESI
WETESLDLYLLPYGCISTGNRIGMIEIVKDAATIANIQQSVVGSRGAFKDEILNQWLRDK
CVNEDRFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKS
FMGISKEWVPFVLTPDFLYVMGTAGKKSSPHFQKFQDVCVKAYLALRHHTNQLIILFSMM
LMTGMPQLTSKEDIDYIREALTVGRSEEEAERHLLEQIEICREKGWMVQINWFVHLVLGI
KQGVEKRST
>A0A674GYL0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCASSSFSSMELISIEFILPTSNKHTKAPETMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQELQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKIINNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
DEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSSLDVGLTMQLLDCNFSDENVRAMAVQKLESLDDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCIIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTRCMCEGLFSSPTPHK
PADHPVLYDADDWNAPINQQRRY
>A0A452RJZ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus americanus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRQEYLYGGYPLCQFQYICGCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKVTHPACTSQQLQLREILERRGSGELYEHEKDLVWKMRHEVQERFPEALAR
LLLVTKWNKHEDVAQMLYLRAPGPELPVLSALEAAGLQLPRPHVASFATSTLRKDDELFR
YLLQLVQVLKYESYLDCELAKFLLARALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEA
YCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHVCMRQETYLEALSN
VQSPLDPSTLLAEVCVEQCTFMDSKMKPLWLVYSSEEAGSDGSVGIIFKNGDDLRQDMLT
LQMIQLMDVLWKQEGLDLREALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQ
LFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTI
LRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRES
WKTKVNWLAHNVSKDNRQ
>A0A8C1ZZ05|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWVESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQNIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKRISEEKMQCMQLMSWGEWLRSCYSMTLEAGSLE
NLIDKHEGVIKITMHYDQSQVSSVNLVCRVLQISLKYIGFRSDYVLRVSRKLEFLFEDHH
LNQCKYIRDCLLTNESPHLTLVHCDVVKAMFEKEISTIGSVLAWKTSNPPLPLPPKKRLP
TASTLFPLHTCVWKVHSLFRIHLVKGNKVNAEDAIQVRAGLFHGTELLCKTAVSSESSSR
SEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHY
PIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFP
EYSTQPVVFPAFDKVYEIAQNKRAKANGRGGKKFYIELKEIMERDPLSQLCENEKDLIWT
LRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVR
EFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRS
EMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFGTIKTKTKQAHL
KEAMMTCLRQTGFIETLSDLHSPLNPNILLAGVNVERCKYMDSKMKPLWIVYNNKLLGGD
TVDIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSAD
TIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIG
DRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTSNTEK
FGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKVNRHEKENCNLLF
LRLCDPI
>A0A8C1X1M2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
SVLSAMPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKE
AQTYPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERI
LDSKIGVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLE
TESVENLIDKHEGVIKITMHYDQSQVCSVILALKKWQTTHGPEEDIGTRSDYVLRVSCRL
EFLLEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAIFEKEICTIGSVLARKASNPPLP
LPPKKRTPTVRTLSVFPALQLIKGALSFVPLAVRAGLFHGTELLCKTAVSSESSSRSEHV
WNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHYPIAW
VNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYST
QPVVFPAFDKILEKAAEIAGASDSMTIGRGGKKFYIELKEIMERDPLSQLCENEKDLIWT
LRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVR
EFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRS
EMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKLGTIKTKTKQAHL
KEAMMTCLRQTGFIETLSNLHSPLNPNILLAGVHVERCKYMDSKMKPLWIVYHNKLLGGD
TVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSAD
TIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIG
DRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEK
FGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEAL
KQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A8C1LSI5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLETESVE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDY
VLRVSCRLEFLLEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAIFEKEICTIGSVLAR
KASNPPLPLPPKKRTPTVRTLSLHTCVWKVHSLFRINLVKGNKVNAEDAIQVRAGLFHGT
ELLCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTH
LNKYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQT
NPYTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTIGRGGKKFYIELKEI
MERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKL
SPRDALELLDFNYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLL
ERAQSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKA
VNELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSNLHSPLNPNILLAGVHVERCKYM
DSKMKPLWIVYHNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPY
GCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFI
LTHDFIHVIQQGKTGNTEKFGNFFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSV
KDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A8C2HHQ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLETESVE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDY
VLRVSCRLEFLLEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAIFEKEICTIGSVLAR
KASNPPLPLPPKKRTPTVRTLSLHTCVWKVHSLFRINLVKGNKVNAEDAIQVRAGLFHGT
ELLCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTH
LNKYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQT
NPYTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTIGRGGKKFYIELKEI
MERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKL
SPRDALELLDFNYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLL
ERAQSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKA
VNELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSNLHSPLNPNILLAGVHVERCKYM
DSKMKPLWIVYHNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPY
GCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFI
LTHDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVK
DIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A8C1CYV4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSPELPKQ
KYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLKMCVQEYQGKYILKVCGCDEYLLEKY
PISQYKYVRSCIMLARLPNLMLMSKDSLYSQLPMDNFTMPSYARRISTATPYMNGEASTK
SLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGIYHGGEQLCDNVNTQRVPCSNPRWNE
WLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLASGKCQPVDYTHTLVSGKMALNL
WPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSSPVKFPDMATIEDHANWIISREMG
YNYCQSGQSSRLARDHAMTEADIEQLRQLSNRDPLSEITEQEKDFLWRHRQYCVNIPEIL
PKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTD
DKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFG
LLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYM
DALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFHNGD
GKIFFRPNIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNS
STLHQWLKDKNRGEMYDMAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDF
GHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQ
HANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTT
KMDWIFHTIRHHAQN
>A0A8C2VXG3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chinchilla lanigera|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7L1MF88|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bombycilla garrulus|TrEMBL
MELGDHEQPVVMREENRRRRRRMKPHCASSSFSSMELIPIEFILPTSKKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVTCRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNDDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKGQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRT
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTHQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A670HZK2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podarcis muralis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNIESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWAINSNLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLQYEMHVLDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMSVIEDHANWTISRELGFNYSHAGLSNRLARDNELRDCDKEQLRSICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLIKDWPPIKPEQAME
LLDCNYPDPMVRAFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K8AJ79|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cnemophilus loriae|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSLSSMELISIEFILPTSNKHTKAPEIMLLE
VAGNCTVEQMKAQIWMRAIEISQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKNVGKIYVVQKQKPSEVVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYSMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPAEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPVALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESVKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDICVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6G1RTU2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hypotaenidia okinawae|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPSD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAVN
RKSSNLPLPLPPKKTRAMTSVWDISSPFKITLLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYA
ENATALHIRFQEYSKQPINYPAFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSHLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A668REL3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MAPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLTTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYSKLDKGQIIVVIWVIVSPTNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPME
FFTMPSYARRISTATPYMNGETATKNLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLTYDMYIPEVPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHY
SSPVKFPDMSTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHDCINMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMVREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTILKFHLLSS
>A0A668UH72|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRSKMFRISEERMQQIQMMTFSEWVQACYSPQLEPA
AVTAITAGVNDAPFPFLQDSASLKVSLSCTPNELMEQALRKWLTTHGSEDAVWRGQYILR
VSQCLEFLGGDHPLIQYKYIRSCLQAKETPHLTLVHTSAVKTMFDKEISAIGAVVSRKSS
NPPLPLPPKRRAPTVSPNIMHDSVNNIISIFMILVKGSKVNAEETVQVRAGLFHGTELLC
KPAVSNESSGRSEHTWKDNTLEFEISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNPHINK
YQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPY
TENATALHIHFPEYSSHPIVFPPFDKVTQHSIVIFSFFDSMSLGRGVKKFYMELKEIMER
DPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPR
DALELLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERA
QRNRQIGHFLFWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQVEALSKLKSVNE
LIKLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDINVEKCRY
MDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVP
YGCLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAI
EEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPF
ILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSV
KDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A668W1N0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MDRQQIQVSDEESQVPREESRRRRRKKAITSSCSNSMDQITVEFVLPTAARGGSGSDTLQ
LDVAGNWTVEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTCKPLPEHLLSKINNGHILVVIHIGTASQTIKVSID
DTPTLVLVSFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLK
NGEEIHLVLEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKQPQIPNSKGKQSFILRLLYYVNLLLIDHRSLLRQGEFILHM
WKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDWAVGG
EDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHECMRVPRAYPKLLG
SVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDD
DVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSKHYQQRYA
VLLEAYLRGCGENMLQDFRKQVTQALQKVTREIKTMSADKYDVTPQVVFQLRQKLENLQS
SGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADSTTLSKDPIGIIFKDGD
DLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIANIQQSVV
GSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITE
SGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKA
YLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICR
EKGWMVQINWFVHLVLGIKQGVEKRST
>A0A668W2B1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
GNSKSQVPREESRRRRRKKAITSSCSNSMDQITVEFVLPTAARGGSGSDTLQLDVAGNWT
VEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDCIRYWR
ALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPRRI
ELSERDPKLYSMDPWVTCKPLPEHLLSKINNGHILVVIHIGTASQTIKVSIDDTPTLVLV
SFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLKNGEEIHLV
LEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVL
GIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNIKIKDLPKG
ARLNLQVICGKQPQIPNSKGSSYQESTAGSSSLDGKSRLLYYVNLLLIDHRSLLRQGEFI
LHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDWA
VGGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHECMRVPRAYPK
LLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETL
EDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSKHYQQ
RYAVLLEAYLRGCGENMLQDFRKQVDMTEALQKVTREIKTMSADKYDVTPQVVFQLRQKL
ENLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADSTTLSKDPIGII
FKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIANI
QQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDN
IMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQV
GVLWHLETGW
>A0A7L4HPM9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scopus umbretta|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQANCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRTGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLRYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A4W3H1W4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMIVTLECLREATLVSVKHDLFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDHEVQDFRRNILSVCKEAVELRDVNGANSRALYVYPSNVESSPELPKH
ISNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCMPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQSKYILKVCGCDEYLLEKYPLSQYKYVKSCIILGRMPNLMLMTKDSLYTQLPLD
TFTIPSYARRISTATPYMNGEASAKFLWAINSVLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGDPLCDNVNTQRVPCSNPRWNEWLTYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTDTLVSSKMALNLWPVPHGMEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPSMSMIEDHANWTMSRELGYNYCLVGLSNRIACDSNLTEGDIEQLRSIGSRDPL
SEITEQEKDFLWRHRHYSVNVPEILPKLLLSVKWNSRDEVAQMYCLLKDWPPIKPEQAME
LLDCNYPDPMVRDFAVKCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQGFMSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQIQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEGYDGAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEICYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHTLN
>B0EQA4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Entamoeba dispar (strain ATCC PRA-260 / SAW760)|TrEMBL
MFCSCGMDLSPNSISSENNTTTIIGWTDIYLFDYRKLMISGNYSQAIMLPPVIPIGIPVT
EFGNLNQLNGKIQFKLPTGPTIQFDNSTVDITKELNEKCELNEEEQKKINTLIVTTNLLK
EIEKEDKELIWRGRQFILNEETLHLHPSSIVLLCQSVPWDKPKEVKVFEQLIQKWPKVSH
IIALRLLHFSFANSFIRQYAVNCLVECNDEHLSTIMMQLIQSLKFEATPLSDLAIFLIHR
ALNKRSTIGRIFFWLIKSELHIPETQRRFALLLEAFLMVCGAQRTVIKNQLDLCKKLTSL
YTQQNQTWKNDINQLTKELNNIILPQITYVPFKSSLKFTKIVAENCKVLDSLRKPLFLTF
KNEDPEGDPIYIIFKKDDDLRQDMTSCSY
>A0A4W3H472|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPGMQYHQDLWSEDENPDVEVEFLLPTGIYLNFYVPRSSTISYIKKLLWQQAQQQPLFH
TLNEPDAYVFTCINHTAEREELEDERRRLCDVRPFLPVLKLVAREGDRAEKLINSQISLL
IGKGLHEFDCMQDYEVAEFRLKMRQFCEDKESERLRMSWQDWMEYSFPRELEPIQEAPDN
NMIRTLSNRNIVINVKFQYNEESFSFQISPQSHPGTLMQMAVKKKATVFRHKTVEHTEDY
TLQVNGTEEYIYGNYPLGQFKHIWNCMYSSSTPHLTMVHSSTINSLKGEQSNSIAQVPKS
RTYSKPPPLPIKKVIIALQELRSLLVVQAGLFHGSEMLCKTVSSHEVSVCSEPAWDQALE
FDIHFSDLPRMTRLCFALYGVIDKAKKARSTKKKSKKADCPIAWVNTMVFDYKDQLKTGD
VWLHMWPSIPDEKGELLNPMGTVQGNPNTDSAAALYVRFRNMGSYPIYYPSFDKILELGK
NGDHSKASPTEQQQLKEIMERKSCTEFFEDEKDLVWKLRWESRDHYSDALAKLLSITKWN
KHEDVAQMIYLLQSWPELPALHALELLDYSYPERYVRSFAINCLKNLRYEELFQYLLQLV
QVLKYEPYLDSELTKFLLNRALANKKIGHFLFWHLRSEMHVPAVSLRFGLILEAYCRGNN
YHMKSLMKQCESLKKMKALNDFVKSSSQKTTKPKTKEALHLFMRQEAYMEALSNLHSSLN
PSSLLTDLWVDKCKFMDSKMKPLWIVYKNEKYDGDPMGVMFKNGDDLRQDMLTIQMIQLM
DVLWKRQGLDYRMIPYACLSTGDKTGLIEVVSRSETIANIQLNKSNMAATAAFNKDALLN
WLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLG
NFKSKFGINRERVPFILTHDFVHVIQQGKTSNSEKFERFRKYCEHAYMILRKHCPLFINL
FALMRAAGLPELSSSKDIQYLKDSLALGKTEEEALKHFKMKFDEALRESWKTKVNWMAHN
VAKDNRS
>B0EPD2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Entamoeba dispar (strain ATCC PRA-260 / SAW760)|TrEMBL
MCSRLTRTTFSVPRVTGTTSVLRKNIPVIRVIVENEGKTFTPINTPQQIINFYYDPKKTK
EKYYFCLNHQPYYFDRLSEPFFECKFCIYCNSYGYWPTFTLVKVEQCINYKPINSFLNFL
ESNKMTFDCIGNEFLLVLKANTDECRDFRATLARILQEKIVLFESDVIDKFGDDTQSQQD
AKDIYEENEYVYVESEPPIPTNCIELKINGRYGVDMSMKTIVQKPTDTIAKVINNLFTKL
YTMKPKIFDKNSKATDFVLKVRGSNEFLIPYNNDKIEYTLNDFDYIRKCVRLNQNIDVVL
FNRKKMYQYMFDKEKIVLLKQFNTFVGNDYWSKLQKNTNDLSQRAAQIQFSIQIISIENI
KYLKIIKKEDKKETISITSFRAYFALSLHYGIRYLEKEKFTNVFQVSEGKLLLKEPFNVS
FETLLSSLPKETKMIISLYMTELPVGISVNEINKKDICLATINCKLVDHHKYFMKGLFNV
GMWERTEPNPIMMCCENTSPETCKLRYCVIEFDKPIKMDTFIGTEEEMNVPINTSQKLDL
NDTKIFKEAVEADPLTVLSQEDCRLLWKYRYLVEKTKPGSLARLVSAVDFTQQSEVLELH
RLLNKWPLLKPTQALELLDFRFPDEQVRLFALKCLDAMKDYELVNFLPQLVQALKFELHH
QSNLAYFLLRRALRNKNIIGHQFFWFLKAEMHDNRVTERYGVLLEAFLNGCENYRTELYN
EVTFQNQLVVIANKVKQIEVKEEQKQLLKDSLAKLKYPEEMSLPLDSRFRIKKPVPNTGN
VFSSKKKPLMLVLENVDPLGDNIMVIQKVGDDLRQDVLSLQMIQLMNNIWKSAGLDLRML
PYHCTATGNEIGMLELVQDSETYGKIIADEGGQGTLRICKEDLLTKWLKKQCSRKESKVT
FEQAVENFTYSCAGYCVATYILGVGDRHSDNVMIRRDGRFFHIDFGHFLGHFKSKFGVKR
ERTPFKFTQHFAHVMGGKGSTQFSIFEDLCIRAFACIRKQGSLFIYLFRLMLATGIPELQ
HEKDIEYMRDTFMFDKKDDEAKEAFRQLIYECLEAKSQTLNDMIHDFVHYK
>A0A2G9QH29|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lithobates catesbeianus|TrEMBL
LLWEKAQQEPMFHTLGSPSSYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGD
RAEKLLNSQISLLINKGLHDFDSLNDAEVNDFRTKMRLFCEQIASQRQHMNWEIWMESNF
PLQLEPSTTLFSKPFSSKTIMINVKFENSEESFTLQVSPRDLPISVIRMALRKKSKVSGQ
HCPGGAEEYTLQINGLLAYIYGNYPLCQFKGEALSKLKGLNDFVRSSVQKTKDKAQAKEA
MHMCLRQETYLEPLSHLYSPLDPNLILTDVWVTPYGCLSTGDKTGLIEVVMRSDTIANIQ
RNKSNMAATAAFNKDALLNWLKSKNPGFLRF
>A0A2U3ZTU9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Odobenus rosmarus divergens|TrEMBL
MFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKIG
VLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEHEPSILEN
LEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDEVSPYDYV
LQVSGRVEYVFGDHPLIQFQHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHGTELL
CKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTINPCK
YQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPY
TENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDR
DPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPR
EALELLDFNYPDQYVREYAVDCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNS
LIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMK
PLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLAT
GDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLS
CAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A851Q073|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anhinga anhinga|TrEMBL
MDLGDYEQPVVMREENKRRRRRMKPHCASSSLSSMELISIEFILPTSNKHTKVPEMMVLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>F7EIC3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus tropicalis|TrEMBL
MKKETLLCRGNMLASGMELDSYEQPVVLRDENQRRRRRMRPHSATSNMFPMEQIPIEFIL
PTSNRCSKVQETMLLEVAGNCSVEQMKAQIWMHAIEKSHNSDFYQRLTPDQFLLQYQKKG
QWYEIYDKHQVIQTLDCIMYWKVLQKTVGKIHIVQKEKIPEEMIEYQKTLNYLIGYDVTD
VSNVHDDELEFTRRRLVTPRMIELSRRDARLYSMDPWVTCKSLPEYLCQRIISNSIFIII
HKGMTSHTIRVSIDDTPDVILHSFFTKMAKKKSLLDISEENSELDFVLRVCGRDEYIIGN
APIKDFHWIRQCIKNGQEIHLVLEKPPDPLMDEVQKEQWPLVDDCTGVTGYHEQLTIEGK
DHEKIFTISLWDCNRKFRVKIIGIDIPVLPKNTELIAFVEANIQHGQQVLSQRRTTCKPF
TEEVLWNSWLEFDIKIKDLPKGALLNLQIFCGKAPTASNKSIVQSPESTASDSKCKNQLL
YYVNLLLIDHRFLLRQGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKETSMAISISLD
KYCHPVALPKHKLVCDPELERPRTEMPNQLRKQLEEIIATDPLHPLTPEDKELLWHFRSE
IVKHPEAYPKLLSSVKWGQQEMVAKTYQLLSKREAWDDCSLDVGLTIQLLDCNFSDENVR
AMAVQKLESLQDDDVLHYLLQLVQSKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRG
CGKAMLDDFTRQVQVTEILHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQNSKLPDKL
PDSFRVPYDPGLRAGSLVVEKCKVMASKKKPLWLEFKCSDTTALSNETIGIIFKHGDDLR
QDMLILQILRIMGSIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAQIQQSTVGNT
GAFKDEVLSQWLKEKCPIEEKFSAAVERFVYSCAGYCVATFVLGIGDRHNDNIMVTESGN
LFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSQYFNKFQDVCVKAYLA
LRHHTNLMIILFSMMLMTGMPQLTSKEDIEYIRDSLTVGKNEESAKKHFLDQIEVCRDKG
WTVQFNWFLHLVLGIKQGVEKHSA
>A0A3P4MV42|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gulo gulo|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSEETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFAKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPLRNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCSKAPALSGKVAADSPSSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDHGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVHVIETLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNANLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSSETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A852DUV5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vidua macroura|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGA
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETAGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8J7NKB8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Atractosteus spatula|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCCLPNGMLVNLECLREATLLSIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPELPQH
IYCKLDKGRLIVTIWVIVSPSNDKQKYTLKTPHDSLPEQLIAEAIRKKTRSMHLSPEQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCITIGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCLGGADPSPPRPLWAFSSPLRVRLLCATYVNVNIRDIDKGTGAV
KPRGVRVQEQYSPVRSGYKSSTPSEIRLQEQYSSVRSGYRSSTAQLDCSAVRSPLPRCAE
PDCPVLCFPRWNEWLTYDIPLFDLPRSARLCLSICSVKGRKGAKEDQTPTRWVGVLYYTS
YYNIVHCTSLCCCVVLHCMMMMMMKPVVRAQETPCVELEFPWFSHAVRFPDEQQVEEHAN
WTISRELGYNCCLLGMSNRLACDSSVSQTDVDQLRSICSRDPLYELSEQEKDFLWRHRHY
CVNIPESLPKLLLSVKWNSRDEVSQMYCLLRDWPLIQPELALELLDCNFPDPVVREFALR
CLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFFWHLKSEMHN
KTVSRRFGLLLEAFCRGCGMYLKHLNRQVEAMEKLINLTDTLKQEKKDETQKTQMKFLVE
HMSRPDYMEALQGFVCPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFTNN
EIIFKNGDVCSAVRDTAVDKGYLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDC
VGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEACSALSLLTHLAVTLS
NPCLSSLRYDRAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHK
KKKFGYKRERVPFVLTQDFLIVISKGTPECTKTKEFESVIMCLINSARFQEMCYKAYLAI
RQHANLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGW
STKMDWIFHTIRHMPNDH
>A0A4W4EW00|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MPPAMTDLLDLWVEPGLDGDDQVTVDFLLPTGVYIKMDVPRQSSLQCIKQMLWKQAQGYP
LFTLLGEMDSHIFECVNQAAVHEELEDESRRLCDVRPFLPVLRLIARNCGRAERLLDSKI
GVLIGKGLHELDALQDQEVKDFRSKMQRISEENMQCVHMMSWGEWLQSCFSPQIEAGPVN
GYCDGSEGEVKIIMHYSESQDTASLKVPLSCTVAELMEQALRKWLTTHGSEEDEGCLGDY
VLRVSAKLEFLFGDHPLHHYRKKRKYKSCALLQSCLTIIFIKIQKLISKTIKFYVRSCIR
SQLNIFVWVILNDTYLKVNRGCSCSSWSCVCMQVQVRAGLFHGTELLGKVAVSSESSGRS
EHVWNKALEFDLSICDIPRMSRLCFAIYAVMDKVKKQKSTKSVQMNKHQTIRKSGKLLYP
IAWVNTMVFDYRGQMKTGDITLHTWSSFPDELEEMLNPIGTIQTNPYRENATALHIRFPE
YSPQPVVFPPFDKILEKAAEIAGASDTLSMGRGGKKFYVELKEIMERDPLSQLCENEKDL
IWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQ
YVREYAVNCLQDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLRRAQANRKIGHFLFWH
LRSEMHMPAVCVQFALILEAYCRCSVPHIEVLKKQVEALSKLKAVNELIKLGTIKTKKMK
EAQLKDAMMKCLRQTGFIETLSDLHSPLDPQVLLAGVNVERCRYMDSKMKPLWIVYNNKL
LVGDTMGIIFKNGDDLRQDMLTLQILRLMDILWKEANLDLRIVPYGCLATGDRTGLIEVV
SYSETIANIQKNSSNMAAAAAFNKDALLNWLKDKNPGDALEKAIEEFTLSCAGYCVATYV
LGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTG
NTEKFGSFRQNCEDAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTD
EDALKQFRQKFDEALRESWTTKVNWMAHNVAHPS
>A0A6J0X1S7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Odocoileus virginianus texanus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSMSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
SLRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGAVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A2U3WRQ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Odobenus rosmarus divergens|TrEMBL
MSGMELKHHEQPVVLREDNGRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRNSKTPETA
LLHVAGHGNVEQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQ
TLDCLRYWQVLHRSPGQIHVVQRRAPSEETLVFQRQLTALIGYDVTDVSNVHDNELEFTR
RRLVTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSA
DDTPGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCL
KNGEEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDC
DRKFRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFS
IKIKDLPRGALLNLQIYCSKAPALSGKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRH
GEYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPD
PEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVK
WGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVIL
EAYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNS
NLPESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLYFQKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGEKHSA
>A0A1A7Y575|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Iconisemion striatum|TrEMBL
MPPGKYGMQEEWEKEGDLNIIMDFLLPTGIFLKFPVSRNDTIKTIKKMVWRNAKTEALYC
GLGDPEGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNSHICSL
IGKGLHEFEAQKNHEVDEFRSKMRTFCEEKALERQNLPWQQWMEYSFPCDLEPCCSPPVH
GGTKSKNTKKLFINVKFEACDESFMLQQDPQDLPVALMKSALKKRATVFRSVRQESEDYT
LQVSGRWEFIYGSHPLGQFKYIFSCVRNGQNPQLTMVHHSTISKYQEEQGQLCSQMGKTR
SQSRPPPLPMKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSDPLWDQKLDFDINVSDLPRMSRLCFALYAVIEKNKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFILSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLICFPNI
RPHPLYYPPLEKIIVMEGNGDAGFATKVERMKLKEIMDNKNSTEFFEDEKELLWKLRTDV
RDCYPESLSKLLLITKWSKREDVAQMVSLLRNWPDLPAIQALELLDYSFPDPAVRSFTIR
CLRKLSDNELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVA
SVSLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDIVKSGCQKMTVEDLKLCIRQE
SYMEALSNLMSPLNPSIILLEICADKCRFMDSKMKPLWMMYKNPSEHADMVGIIFKNGDD
LRQDMLTLQMIHLMEDLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSN
SAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEWA
YKILCKNGTLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEEEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A6P6D5C5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Octodon degus|TrEMBL
MPPGVDCPMEFWTKEENQSVMVDFLLPTGIYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVDQTAEQQELEDEQRRLCDVQPFLPVLRVVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRTKMRQFCEDAAARRQQLGWEDWLQYSFPLQLEPSARSGGP
GALLVPNRALLVNVKFEGSEESFTFQVSTKDVPLALVACALRKKATIFRKLLVEQPEDYA
LQVNGRHEYLYGSHPLCRFQYICSCLHNGLTPHLTMVHSSSILAMRDEQDDPTPQVQKPR
PKPPPIPSKKPSSVSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWKQRLEFDISICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANIMLFDYRDQLKTGERCLYMWPSAPDEKGELLNPAGTVRGNPNTESAATLVICLPEVAS
HPVYYPALEKILELGRHGEQRGHITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQ
ENFPEALARLLLVTKWHKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKS
LRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPS
VALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQAKELMHLCM
RQETYLEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEASSTGSVGIIFK
NGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQL
NKSNMAATAAFNKDALLNWLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGY
CERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKF
NEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C2DI89|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVAQS
GKSRSVKKILVNVKFEGSEETFVLQQDPQDLPMLLKRNALRKKSTVFRAAKQEKPEDYTL
QVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQMSRTRA
PSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGMNGEKVVTTKEEHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQ
RYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHVRSFTIRCL
RNLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRSEMHVPSV
SLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIK
QDTYMEALSDVVSPLNPSIVLCELCTDKCKFMDSKMKPLWLMYKNKYDHVGIIFKNGDDL
RQDMLTLQMIQLMDVLWKTEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECC
EQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFN
EALRESWKTKVNWMMHTFAKDNR
>A0A6J0D2A5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Peromyscus maniculatus bairdii|TrEMBL
MPPGVDCPMDFWTKEESQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEVAAHRQQLGWEDWLQYSFPLQLEPSARSWRA
SILRVTNRALLVNVKFEGSEESFTFQVSTNDMPLALMACALRKKATVFRRPLVEQPEDYA
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPAKKPSSVSLWSLEQPFCIELIEGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVICLPEVAP
HPVYFPALEKILELGRHGERGRVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
RFPEALARLLLVTKWNKHEDVAQLSQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAI
KSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHM
CMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGSVGII
FKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANI
QLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFR
GYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRV
KFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C2D5P4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLHH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSADLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKIAHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDEYFLEKHPLSQYKYIRSCITLGRLPHLMLVSKDSLYSQLPSS
GFMAPSYSRRTPQPSPCPGGADPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDEQQIEEHANWSISRELGYSYCLGLSSRLACDSSISQADAEQLRTLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQIYCLLKDWPLMQPESAL
ELLDCNFPDPMVRDFALRCLIQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIREKNKGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKNQQDALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A8C4R831|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eptatretus burgeri|TrEMBL
MVRRIPKENHTCDRVYSPFHLVKTSQMGETDKNPLASHLSFKSRHHRQGMRPHTFNHFAG
VEVLTLEFVLPSDGQSENAGETLRLDIPGNITVAQMKAHVWSQAMDKNVLAKLYQNASVN
AFVMMYQKKGQWYEIYDSQQIVQTLDCVAYWKALRSQSCRIHIKERMKESDESCRFQAEL
DHMLGIAMHDLCSSNDDELEFTRRKLTTARRLEVLNRDRMQYAADPWIVTTALPSYLQER
IPNNELFLTLHRGNSSQKIKIKADVFPGTILRMFLQKVDKKKELYDVPEGCTADSFMLKV
CGREDYLLGDVSIRDFHWVRCCLRNKQEIQLEVVIPPDPTNDRVEVEDWPLVDDCTGMTG
MHEQLTLIDKDHEQVFTISLWDCSHKFRLKLVGVDIMVLPRELEASEVYVEASICHGLNV
LATVCTPVQPSAEEVVWNMWLEFDIKVRDLPRGARLNLSLWGRKGSCKSRLLYYVNLLLI
DHRSLLRQGEFILYMWRHPDKGEAQGSIEADKISSATNPDNEDSMAVRFVLNTYCFPVAL
PKGRISEPPAERPAVLHPGSNEHQRLEEIVESDPLRPLSNEDRALLWQQRYQCISRPKAL
PKLLRSVDWGSVEAVLETCMLLERCEDSCLDVEVAMELLDCHLVDEGVRTIAVQRLDELA
NDHVLRFLLQLVQALKFEPYHDSALARFLIKRSLRSKRIGHFLFWYLRSEVADSPHYRQR
FAVVLEAYLRGCGHAVLQDLHNQIKVISCLQDVAVRIKAMIPDRNDIPASVTSYLRELLH
EAPFPDCFRVPYDPCLIAGKLQVEKCKIMASKKKPLWLEFSCVGLSSFSEGSIGIIFKHG
DDLRQDMLILQILVLMEAIWESQSLHLYLLPYGCISTGNNIGMIQIVQDGTTIAKIQQSK
VGNTGAFKDEVLHQWLQEKSPNQDQLVLEKFVHSCAGYCVATYVLGIGDRHNDNIMITGS
GNLFHIDFGHILGNTKSILGVNRERVPFVLTPDFLYVMGASRKETSACFNNFQEICMKAY
LALRQHTDLLITLFSMMALTGMPELSCKKDIEYMREALMVSRREGDAKKHFLEQIEICRD
KGWTVQLNWFIHLFLGIKQGSPGKNNLL
>A0A2K5PUT8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cebus imitator|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLNGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRTKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHFSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLDQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISISDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLHMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
YPVYYPPLEKILELGRHSECIRVTEEEQLQLREILERRGCGELYEHEKDLLWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLGALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSSGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A3P8RK47|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amphiprion percula|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRCKMLRISEERMQQVQMMTCTEWLQACFSPQLEPA
AGTAIMDGVNDRPSDLKVIIHFDQSQDSASLKVPSSSTPTELIEMALRKWLTTHRPEEEA
WKGQYMLRVSRCLDFLCGDHPLIQYKYIRTCLQAKEPPRLTLVHTSAVKAIFDKEISAIG
AVVSRKSSNPPLPLPPKRRVPTQVQTCVWDVSSPFKIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESSRRSDHTWKDSTLEFDISVCDLPRMTRLCIAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TVQTNPYTENATELHIHFPEYSSHSIIFPPFDKILEKAAEIARANDCAPVGRGGKKFHIE
LKEIMDRDPLSQLCENEKDLIWTLRHDCHENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLSPRAALELLDFNYPDQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAQGNRRIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALS
KLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGI
NVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAN
LDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSG
DDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A6P7Z6I1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcaecilia unicolor|TrEMBL
MPPAMTDSFDIWAVDSQITADGPITVDCLLPTGIYVQLDVRRETTISHIKQLLWKEAQTY
PLFHLLMAIDSYMFECVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSKI
GVLIGKGLHEFDALEDPEVKEFRSKMRKISEEKIQSLLGLSWLDWLKRTFPPELEPSIPE
NFQDKLYGGNLVVAIHFDNCQDVFSFQVSPNMNPVKVNELAIRKRLTIHGREDENINPSD
YVLQVSGKLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCNIKKMCEQEMNAIEAAIK
RKPTNLPLPLPPKTRTMSLMAQSVWNFCSPFKILLVRGSKVNAEENVKVQARAGLFHGTE
LLCKTAVSSEIPAGNDYIWNETLEFDINVCDLPRMARLCFAVYAVMDKMKTKKSTKTTNT
KYPTIRKAGKVHYPVAWVNTMVFDFKGQLKTGDITLHCWSSFPDELEEMLNPMGTVRTNP
YPENATALYIKFQEYSKLAIYYPPFDKILEKAAEIARQSDSMNMSGRGGKKFYIELKEIM
ERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWSKLP
PREALELLDFNYPDQYVREYAVNCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLE
RALANRRIGQFLFWHLRSEVQIPQISVQFGVILEAYCRGSVAHMKVLTKQVAALNKLRTL
NNLIKLNAVKLSRAKGKETMQTCLKQSTYREALSDFQSPLNPSVILSEMNVEKCKYMDSK
MKPLWIVYSNKVFGGDPVGIIFKNGDDLRQDMLTLQLLRLMDMLWKESGLDLRIVPYGCL
ATGDRSGLIEVVSAAETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFT
YSCAGYCVATYVLGIGDRHNDNIMVRKTGQLFHIDFGHILGNFKSKFKIKRERGPFILTY
DFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQ
YLKDSLALGKTEDEALKQFRQKFDEALRESWTTKVNWMAHTMRKDYRS
>A0A1S3LVG7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo salar|TrEMBL
MPPRPSSGELWGMHLMPPSIMVDCLLPNGMILTLECTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDAEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVSIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8C6K7F8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Melopsittacus undulatus|TrEMBL
MELEDELHEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMML
LEIAANCTVEQMKAQIWVRALEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQT
LDCILYWKVLQKKVGKIYVVQKQSPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRR
RLVTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLRKITNNNIFIIIHRGTTSQKVKVSID
DTPDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLK
NGEEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCN
RKFRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDI
KIKDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDPKCKTQLLYYVNLLLIDHRFLL
RSGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIT
SDPQGDRARAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSS
VKWGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMRLLDCNFSDENVRAMAVQKLESLEDDD
VLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAV
ILEAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQ
SSKLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHG
DDLRQDMLILQILKIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQST
VGNTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMIT
ETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVK
AYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVC
RDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6J2LMC8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phyllostomus discolor|TrEMBL
MPPGVDCPMEFWTSEENQNVAVDFLLPTGVYLNFSVSRNANLSTIKKALWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYCFPLQLEPSARTWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDMPLALMTCALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHRGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGEYCLYMWPSVPDEKGELLNPTGTVCSNPNTESAAALIICLPEVAP
YPVYYPALDKILELGRHGEHGRFTEEELQLREILERRGSGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLCLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSIHHMRVLMKQGEALSKLKALNDFVKVSSQKTPKPQAKELLHVCMRQ
ETYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVMYCNEEAGSNGSVGIMFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>V8NRF8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ophiophagus hannah|TrEMBL
MELETSDQAVVMRDDNKRRRRRRMKPYCTANTLSSTELISIEFVFPTTSIVLDVPTNCTV
EQMKAQVWMRAVEGHQTSDLFRRITPDQFLLLYQKKGQWYEIYDKHQIIQTLDCILYWKV
LQKKVGKIHVVEKPNPSEEVQEFQNQLNYLIGYDVTDVSNVHDDELEFARRRLVTPRTIE
VSCRDPKLYSMSPWTTSKPLPEYLLSRIANSNIFINIHRGTTSQKIKVAVDDTPDVILQS
FFTKMAKKKSLMNIPEDYSEQDFVLRVSGRDEYIIGETPIKNFHWIRQCLKKGDEIHLVL
DEPPDSNQDEVQKEEWPLVDDCTGVSGYHEQLTIHGKDHERVFTISLWDCNRKFRVKIIG
IDIPILPRNTDLTVFVEANIQHGQQLLSQRRTTAKPFTEEVLWNIWLEFDIKIKDLPKGA
LLTLQIYCGKTPPPSAKGNPHPQDSPSSDPKYKTQLLYYVNLLMIDHRSLLRTGDYVLHM
WKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHKIAADPPGGRAR
VEMPNQLRKQLEEIIATDLLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWGEQKLV
AETYQLLAKREAWDQSALDVGLPIQLLDCNFSDETVRTMAVQKLEGLEDDDVLHYLLQLV
QNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLKDFLKQVQVTELLHKVT
REIKAISAEKYDVTPQVIAQLKQKLERLQDNKFPECFRVPYDPGLKAGALVVSIIFFSLS
KVR
>A0A8B9J6Z5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MKAFTSATSVPVDHLVMEFVLPTTNKTTKNPDTVQLEVLGNWTVEQVKAQLWLRAVATNL
CPEFYQKFSPDHTILLYQKKGSWCEIYDKHQVFQTLDCIRYWKALKKEIGKIHLVLRPQS
SEESVQYQKFLNHLIGYDVTDVSNVHDDELEFTRRKLLTPRKIELADRDPKLYSMDPWIT
TKTLPDYLLSKITNGYILLVIHIGTSSQTIKVSIDDTPVQVLQSFFTKIANKRALLGIPE
EVNESDFVLRVCGREEYIYGNYAIKDFHWIRQSLKSGEEIHLVLEPPPNPEQDGVQKEDW
SQVDDCTGVAGTHEQLTIDEKDHEKVFTISLWDCNRKFRVKILGIDIPVLPRNSELIVFV
EASVFHGQQQLAYERTSPKPFTEEVLWNTWLEFNIKIKDLPKGARLNLQVSCSKAQTQTS
RDSAVHDCKTKSRLLYYVNLLVIDHRSLLRQGEFILHMWKMPEKSAEDSSVNADKLTSAT
NPDKTSSMAIAVLLDKYCYPVALPKSRDSRDSSDMEGERGKREMPNHLRKQFEQIVATDP
LHPLSSEDKELLWHFRQDCMRHPSAYPKFLGSVKWGKQEDVMATHQLLERSTTWDRSPLD
VGLAMQLLDCHFSDAKVRTMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALAQFLLK
RALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAFLRGCGEVMLQDFSKQVEITEALQ
KITREIKAMSAEKYDVSPQGELMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQD
MLILQILLIMESIWETESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGA
FKDEILNQWLRDKCVSEEKYQQAVDRFVFSCGGYCVATYVLGIGDRHNDNIMITESGNLF
HIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTTGKKSSPNFLKFQDVCVRAYLALR
HHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGCSEDEAQKHFLDQIEICRDKGWT
VQFNWFLHLVLGIKQGVEKRSA
>A0A8B9J9A6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLISVKQQLFAEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPSVESSPQLPQH
IYCKLDKGRLIVTIWVVVSPSNAKQKYTLKIAHDCLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCITVGKLPHLMLVSKDSLYSQLPAS
GFVAPSYSRRTPQPSPCPGGSDPSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLTDLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
SFNQMVVFPDEQQIEEHANWIVSRELGYNYSLSLSNRLACDSTISQAELEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLAVKWNSRDEVSQMYCLLRDWPLMQPESAL
ELLDCNFPDPMVREFALRCLIQGLTDDKISQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KHEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKEKNKGEGYDKAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGMQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A671SHH9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
VCINDVVCAMPSAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLL
LWKEAQTYPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGR
AERILDSKIGVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYT
MPLEAGSLESLIDKHEDVIKITMHYDQSQVSSVNLVCITELMDQALKKWQTTHGPEEDIG
FRSDYVLRVSGKLEFLFEDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIG
SVIARKTSNPPLLLPPKKRLPTLHTCVWKVHSLFRINLVKGNKVNAEDAAKIQVRAGLFH
GTELLCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKN
THLNKYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHYELEEMLNPIGTIQTNPYT
ENATELHISFPEYSTQPVVFPVFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMERD
PLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRD
ALELLDFNYPDQYVREFAVYCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQ
SSRKIGHFLFWHLRSEMFMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNEL
IKFGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGINVERCKYMDSKM
KPLWIVYNNKLLEGETVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLA
TGDHAGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTL
SCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHD
FIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A671T2F3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPAKTDQLDLWAESGLDGDVQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSCGEWLRSCYSTQLGTGSLE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDY
VLRVSGRFEFLFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLAR
KTSNPPLPLPPKKRPPTQLHTCVWKVHSLFRINLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWTFQNPSRSVSVHFALILEAYC
RGCIPHIEVLKKQVEALNKLKAVSELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSD
LQSPLNPNILLAGVHVERCKYMDSKMKPLWIVYNNKLLGGDTVGIIFKNGDDLRQDMLTL
QILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFN
KDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHID
FGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNG
NLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKV
NWMAHIVAHPS
>A0A671SH37|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
AMPSAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTY
PLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSK
IGVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYTMPLEAGSL
ESLIDKHEDVIKITMHYDQSQVSSVNLVLSLHCTVTELMDQALKKWQTTHGPEEDIGFRS
DYVLRVSGKLEFLFEDHPLNQCKVRYVARNGFESSNYIFQGFVNMVKIQHSTTYCFRAMC
SLKFQKLHTCVWKVHSLFRINLVKGNKVNAEDAAKIQVRAGLFHGTELLCKTAVSSESSS
RSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIPWVNTMV
FDYRGQLKTGDIILHYELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVFPVFDKG
RGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDM
AQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVYCLRDMSDDELLQYLLQLVQVLRY
EPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMFMPAVSVHFALILEAYCRGCIPHIEV
LKKQVEALSKLKAVNELIKFGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNI
LLAGINVERCKYMDSKMKPLWIVYNNKLLEGETVGIIFKNGDDLRQDMLTLQILRLMDLL
WKEANLDLRIVPYGCLATGDHAGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLK
DKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFK
SKFGIKRERVPFILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFAL
MLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAH
PS
>A0A7J8DCZ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Molossus molossus|TrEMBL
MCFNFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISSIKKMLW
TQIHNYPMFNLLMEIDSYRFACVNQTAVYEELEDETRRLCDVRPFLPVLKVVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWIDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQISGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAISRNSSNLPLPLPPKKRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGT
ELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTIN
ASKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQT
NPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEI
LDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKL
PPREALELLDFNYPDQYVREYAVGCLRQMRFLLERALANRRIGQFLFWHLRSEVHIPAIS
IQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMHTCLKQ
NAYREALSDLQSPLNPCVILSELYIEKCKYMDSKMKPLWLVYNNQVFGEDSVGVIFKNGD
DLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSS
NVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVK
KNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCED
AYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEA
LRESWTTKVNWMAHTVRKDYRS
>A0A671S5C7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDATGSHSRALYVYPPNVESSSELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTEADIEQLRQLGNRDPL
SEITEQEKDFLWRHRQYCVNIPEVLPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKISSF
CSLFCQGFTYTDLNIMIIRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYM
DALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGD
DLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGG
LKGALQFNSSTLHQWLKDKNKGEMYDMAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKD
DGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMC
YKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMN
DAHHGGWTTKMDWIFHTIRHHAQN
>A0A2K6PG88|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinopithecus roxellana|TrEMBL
MELENYEQPVVLREDNCRRRRRMKPRSAATSLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVASDFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFTIKI
KDLPKGALLNLQIYCGKAPAVSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDTCVKAYLAL
RHHTSLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8C0HLR9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Buteo japonicus|TrEMBL
LNPVLLPVGVIPLFYKASSQQVLTHAQYEPLYHMLSDPEAYVFTCINQTAEQQELEDEQR
RLCDIQPFLPVLRLVAREGDRVKKVINSQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFC
EERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGTGPLHTPAKNIFVNVSFTFQISPKEFPI
TLMSYAIKKQATVFRHETVENPEDYTLQVNGKCEYLYGNYPLYQFQVSLVSCLINDPLPI
WPRLAGRPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSEV
NVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWVNV
MLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVALHPV
YYPSFEGPAEYITYTWAVRGQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQAL
AKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDH
ELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGL
ILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCMKQETYLE
ALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQD
MLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAAT
AAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQL
FHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMIL
RRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESW
KTKVNWLAHNVSKDNRQ
>A0A7K7KS41|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Asarcornis scutulata|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPYCTSSNLSSMELIAIEFILPTSNKHTKIPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYQAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHDSPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A1V4KNZ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Patagioenas fasciata monilis|TrEMBL
MEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYHMLSDPEAY
VFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLLIGKGLHEF
DSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKALGTGPLHTPTK
NIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYTLQVNGKCE
YLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMPVKPPPLPK
KKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVNVCSE
PVWRQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDY
KDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVASHPVYYPPF
EQLLELGRNGEPPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQA
LAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTD
HELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFG
LILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCMKQETYL
EALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQ
DMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVA
TAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQ
LFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCERAYMI
LRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRES
WKTKVNWLAHNVSKDNRHERVKISTLPYDFLSARGQSVLKLNQNPKNP
>A0A061IHE6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cricetulus griseus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
SFTMPSYSRRISTATPYMNGETTTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPL
SEITEQEKDFLWSHRQVGGGRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIK
PEQAMELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLL
KKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLIN
LTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSS
AKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRML
PYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAI
DLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPF
VLTQDFLIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQ
SFDDIAYIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN
>Q4JLV4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cricetulus griseus|TrEMBL
QMLWKHVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSC
DPAEKLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEDKIQSLVGLSWIDWLKHTY
PPEHEASVLENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNLTPIKINELAIQKRLTIHG
NEDEVSPYDCVLQVSGRVEYVFGEHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQE
MIAIEAAINRNSSNLPLPLPPKKTRVISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAG
LFHGTELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKS
TKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPM
GTVQTNPYAENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANMSSRGGKKFLA
VLKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQ
IWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCAL
SRFLLERALNNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEAL
NKLKTLNSLIKLNAMKLNRAKGKEAMHTCLRQNAYREALSGLQSPLNPCVILSELYVEKC
KYMDSKMKPLWLVYSNRGFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRM
LPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDR
AIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERV
PFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELT
S
>A0A7K5VRA4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Platysteira castanea|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAANCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEATIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEVVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K9XPP7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Psophia crepitans|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNVSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLIKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDSPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKTQGLSTKTNLQSHESPSSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVISQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A672U2P6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVHDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQVCKSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFH
GTELLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKH
YPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIRF
QEYAKQPINYPPFDKGFLKVCSSIKFTEVALLWLRMSRTEAYVWNTSDVLPGIGFLVFEL
KYKSLSGKKFYVVLKEIMERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNK
LEDVAQLQALLQIWPKLLPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQ
VLKYEPFLDCALSRFLLERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVA
HMKVLAKQVEALNKMKTLNSLIKLNAMKQSKAKGKDAMQTCLKQNAYREALSDLQSPLNP
SVILSELHVEKCRYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMD
ILWKEAGLDLRILPYGCLATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNW
LKEYNLGDDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGN
FKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLF
ALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTV
RKDYRS
>A0A8C4B0F7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPTMMDVLDLWAELGEVEHVSVDFLLPTGLYIQMEVPREATIQHIKQLLWKEAAGYPLF
TLLGAMEGHMFECVNQTAVHEELEDETRRLCDVRPFLPVLRVVTRSGGHNERLLDSKIGV
LIGKGLHELDSLQDQEIKDFRTKMQQISKEKIQRIQVMSWEEWLRTHFSPQLEVGQVDGM
IEKLCEDGIKVTMNFYKLALRKWANTHGHNNSSCLSDYILRISSKLEILFEEHPLIQYKY
IRECLLAQESPHLTVMHSSVLRGMFERELGCIASVCGHKQSNAPLPLPPKKRPPSVSTCQ
MHTCVWDVQSQFKITLVRGIKVNTEESVYVRAGLFHGAELLGKPAVSSDSSGRLEHLWNT
TLEFDVAVSDLPRMSRLCFAIYAVMDKVKKQPKSIKTPHSKYQTIRKAGKVHYPIAWVNT
MVFDYKGLLKTGDVVLYCWSSFPDELEEMLNPIGTVQTNPYTENATAIHITFPEYSQISV
IFPPFDKILEKAAEMARGSDCPPMVGRGGKKFHIELKEIMDREPLSQLCENEKDLIWTLR
YDCRENFPQSLPKLLLSVKWNKHEDMAQLQALLQIWPTLSHRDALELLDFNYPDQYVREY
AVNCLRDMSDEELSQYLLQLVQVLRYEPYYDCALSRFLLERSQLNRNIGHFLFWHLRSEM
HMPAVSVQFALILEAYCRSSIPHIEVLKKQVEALNKLKAVNALVKTGAVKSKARTKDSHL
KEAMLTCLRQSGFTETLSDIHSPLNPSVLLAEVKCKYMDSKMKPLWIVYNNKLLGGETLG
IIFKNGDDLRQDMLTLQILKLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADTIA
NILKTSSNMAATAAFNKDALLNWLKEKNSGDTLERAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTANTEKFGS
FRQYCEEAYLVLRRNGNLIITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQF
RQKFDEALRESWTTKVNWMAHHIHVFAA
>A0A3P9LWL3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MPPAMTDLVDIWAAHSPLDGQAPVHVTMDFLLPTGIYIQMEVPREATIQHIKLLLWKQAK
SFPLSSFLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVFRLVTRNCGRAERLLD
SKIGVIIGKGLHELDGINDQEVKDFRSKMQRLSEERMQRVQMMSFTEWLQACFSPQLEPS
AGTAIADGANDWPADLKVIIHFDQSQDSTSLKVPSSCTPSVLIEIALKKWQTTHAPEEET
NKDKHILRVSQCLDFLCGDHPLIQYKYIRSCLQAKESPHLTLVHINAVKAIFDKENAAIG
AVVSRKSSNPPLPLPPKKRAPTVQVRAGLFHGTELLCKPAVSSESSGRSNHSLENNTLEF
EISVCDLPRMTRLCFAIYAIMEKVKKKSYKNPHINKYQTIRKAGKVHYPIAWVNTMVFDY
KGQLKTGDMILHCWSSFPDELEEMLNPIGTVRINPYPENATALHIHFPDYGPHPIVFPPF
DKILEKAAEIAGSSDSTPIGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRLDCREN
FPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVSCLR
DMSDEELLQYLLQLVQVLRYEPYYDCALTHFLLERAQKNRKIGHFLFWHLRFPQKKTKLK
SVNELIKLGTIKNTRSKTKEAMLTKEAMITCLKQSGYSEALSDLHSPLNPNVLLSDINVE
KCRYMDSKMKPLWIVYNNKLMSSDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDL
RIVPYGCLATGDRAGLIEVVSSADTIANIQLTSNDPPSSIEEFTLSCAGYCVATYVLGIG
DRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEK
FGSFRQYCEEAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSDEEAL
KQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A2I0M316|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Columba livia|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKALGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMP
VKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWRQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K8WI13|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sclerurus mexicanus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAARRQQLGWAAWMEYNFPLQLEPVAKGFGT
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPVTLMSYAIKKQATVFRHETLQKAEDYT
LQVNGKWEFLYGSYPLYQFQYIRSCLLRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEKPFYIELLQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAP
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMIFLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8D3BTE1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
FGENPSPSALQLLWKQAQTLPFFAALGDMESHMFECVNQAAVHEELEDETRRLCDVRPFL
PVMKLVMRNCGRAERLLDSKIGVLIGKGLHELDAMNDQEVKDFRSKTFRISEERMQGVQM
MTCTEWLQSCFSPQLEPDVADGAADWSADLKVIIHFDHLKVPSSCTTTELMELAVRKWLT
THGPEEEAWRSQYVLRLSQCLEFLCGNHPLIQYKYIRTCVQAKESPHLTLVHNSTVKALF
DKELSTIGAVVSRKSSNPPLPLPPKRRVPTVSPASRMLFPFKIVLVNASKVNAEETAKVQ
VRAGLFHGTEVLCKTAVSSESSGRSDHTWKESTLEFDIPVSDLPRMTRLCFAIYAIMDKV
KKQKSTKNTHINKTGLHYPIAWVNTMVFDYKGQLKTGDINLHCWSSFPDELEEMLNPIGT
IQTNPYTENATALYIHFPEYSSHPVIFPPFDKGRGGKKFHIELKEIMERDPLSQLCENEK
DLIWTLRWDCLVNFPQSLPKLLLSVKWSKHEDMAQLQALLQMWPKLSPRDALELLDFNYP
DQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGNRKIGHFLF
WHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGPTKNAR
SKTKDAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSGINVERCRYMDSKMKPLWIV
YNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRSG
LIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNTGDALERAIEEFTLSCAGYC
VATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQ
QGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLA
LGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A091TQQ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phaethon lepturus|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSVSVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLLEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVDKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A2U9C0P7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPGKYGMQEEWEKEGVQEIMMDFLLPTGILLKFPVSRNDTIKSIKKMVWKNARSEALFC
GLGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRAEKLINTQISLL
IGKGLHEFEAQKNHEVNEFRTKMCIFCEEKAQERQMLPWQQWMEYNFPCDLEPCCTPPHS
GSLKSKNTKKFFINVKFEACDESFMLQQDPQDHPVALMRSALKKKANVFRSVRQEPEDYT
LQVNGRWEYIYGKHPMCQFKYIFSCLRNGQNPHLTMVHHSTISKFQEEQGQMCSQEYKSR
SLSRPPPLPLKKLNTSSLWSITEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFANI
RPHPLYYPPLDKINDIERNGDAASVTKEEYMKLKEIMDNKNYTEFFEDEKELLWHLRTEV
RDRYPENLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAIRSFTIR
CLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVA
SVTLRFGLILEAYCRGNIHHIKLLTKQNEALSKMKTLSDFVKSGSQKLTAEDLKLCIRQE
SYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNNWAPEDMVGIIFKKGDD
LRQDMLTLQMIQLMETLWKREGLDLRMIPYGCLSTGNKMGLIEVVENSDTIANIQRNNSN
SAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERQQDCQSSP
PSKTSSI
>A0A6A4SUN8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MESFNQITLEYPVLMYVGVGVTAFLAGGALIYKIATRKKPTHANVNCWFCNENTVVPYGN
RNCWDCPSCEQYNGFQENGDYNKPIPAQDRANLNHGVSGSLPPSEMDKMQQWVNCQMLLC
KKCNNNQSLKIKLLAAYMPRDDENYDEEIEAYRHHLEQIYKLCMPCQTVVEYYIKYQNRQ
LRTVLLSHQLQRSRDSVKSFEKSSNSLSSPIGVTLLRALAVLLCAFLVGTYFLDFQDQPS
LSSGPQTLSGGVPPPKPLNESNSSGDVPVWQGLLELIPNGTIESAQLMWQHGRDNQLAVV
SVGLLTCLTSIFLAGATRLRRIDAVASVLWFLILCLYLSESYFTGASDWMDTAKHSSASL
CCLVSFTAAVATRKPQGLRRGKYRRYLAGSSAAPPFSNQPTLLSPNLAESFIPTPPPNLS
KLISCKQSRHKCNDSPSSLSGRLSRGLCLGTMPSLKRTDSGYLFSGSRPASQYKDSPPSD
YFSLKSGSRPSSPTPSIAGSCTSSLCSARQRRPLISPARFNICSQKMGLFSAEPEPMLPP
PPVSPLYSTVPPSPIYSGSFSPDISPFQSQNDLSLRDGSVFDKEERSDNGSSSGSSTCMV
GTTTQEPENTPPKARTELGDEVTVAIFALKMVWKNARSEALFCGLGDPDAYVFTCINQTA
EREELEEESRRINDVRPFMCVLRLVAREGDRAEKLINTQISLLIGKGKQPPLLSDRADLL
LQSQRFWCLVVLLLLLLRKGAGFCQRQNKEESFISLRLHEFEAQKNHEVNEFRTKMCIFC
EEKAQERQMLPWQQWMEYNFPCDLEPCCTPPHSGSLKSKNTKKFFINVKFEACDESFMLQ
QDPQDHPVALMRSALKKKANVFRSVRQEPEDYTLQVNGRWEYIYGKHPMCQFKYIFSCLR
NGQNPHLTMVHHSTISKFQEEQGQMCSQEYKSRSLSRPPPLPLKKLVVQAGLFHGSELLC
KVVTSSEVTVCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKAD
CPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRF
ANIRPHPLYYPPLDKINDIERNGDAASVTKEEYMKLKEIMDNKNYTEFFEDEKELLWHLR
TEVRDRYPENLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAIRSF
TIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEI
HVASVTLRFGLILEAYCRGNIHHIKLLTKQNEALSKMKTLSDFVKSGSQKLTAEDLKLCI
RQESYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNNWAPEDMVGIIFKK
GDDLRQDMLTLQMIQLMETLWKREGLDLRMIPYGCLSTGNKMGLIEVVENSDTIANIQRN
NSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIM
IRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYC
ERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEDEALKNFKVKFN
EALRESWKTKVNWMMHSLAKDNRP
>A0A2J8TTI9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pongo abelii|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSILVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQ
>A0A673IZ96|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMRDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWDQWMEYNFTCDLEPCSVVAQS
GKSCSDKKIFVNVKFEGSEETFVLQQGPQDLPMFLKRNALRKKSTVFRSAKQEKPEDYTL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSINEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCIALYGVIEKTKKRPTKKKNKSSDCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGMNGEKTVATKEEHLKLREIVDNKNYTEFFEDEKELLWKLREEVRQ
RYPESLPKLLLITKWNKHEDVAQMVGLLQKWPELPAIHALELLDYSFPDPHARSFTIRCL
RKLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVSSV
SLRFGLILEAFCRGSIFHIKNLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIK
QDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDTLGIIFKNGDDL
RQDMLTLQMIQLMDVLWKTEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECC
EQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFN
EALRESWKTKVNWMMHTFAKDNR
>A0A673GID0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVEMRDASGPHSRALYVYPPNVESSPELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLISTISSLPCQSLTRF
YVSFSTIKTKKIESNREIKTQPYYLQCFNSACFINEHLNDLLQEHCPLAWGNVNLFDYTH
TLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSSPVKFPDMATIED
HANWIISREMGYNYCQSGQSSRLARDHAMTEADIEQLRQLSNRDPLSEITEQEKDFLWRH
RQYCVNIPEVLPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDF
AVRCLEKYLTDDKLSQYLIQLVQVRLIYSTSPVDFIFFCDYQRFGLLLESYCRACGMYLK
HLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQ
LGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIM
ENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQW
LKDKNKGEMYDMAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDH
KKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFI
NLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIF
HTIRHHAQN
>A0A673IRY7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMRDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWDQWMEYNFTCDLEPCSVVAQS
GKSCSDKKIFVNVKFEGSEETFVLQQGPQDLPMFLKRNALRKKSTVFRSAKQEKPEDYTL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSINEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCIALYGVIEKTKKRPTKKKNKSSDCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGMNGEKTVATKEEHLKLREIVDNKNYTEFFEDEKELLWKLREEVRQ
RYPESLPKLLLITKWNKHEDVAQMVGLLQKWPELPAIHALELLDYSFPDPHARSFTIRCL
RKLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVSSV
SLRFGLILEAFCRGSIFHIKNLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIK
QDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDTLGIIFKNGDDL
RQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNS
AATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRET
GQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAY
KILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKVNWMMHTFAKDNR
>A0A6D2YC34|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan troglodytes|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A315UWQ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gambusia affinis|TrEMBL
MDRQQIQVSDEDCEVAREGNRRRRRKKAITSASSASMDQISVEFVLPTVARGGNSPDSLL
LEVAGNWTVEQVKAQVWMKAVSLNLCPDFYQRFCPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPTDESQQYQRYLNYLIDYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPNLYSMDPWVTRKPLPEHLLSKVNNGYILVVIHVSTSSQTIKVSID
DTPSQVLASFFAKTANKRVLLGIPEHLTEEDFVLRVCGRYAVCGNSLGNFTEEYLYGEKA
LQSFNWIRQSLKNGEEIHLVLETPPDPELDLVQREDWAQVDDCTGVAGTHEQLTIAEKDH
ERVFTISMWDCNRKFRVKVLGIDIPTLPKVPELTVFIEASIFHGQQLLAQERTTSKTFNE
EVLWNCWLEFNIKIKDLPKGARLNLQVICGKQPQTSNPKSSYHDNTAGSSTLEGKTKNRL
LYYVNLLLIDHRSLLRQGEFILHMWKMLEKSEESSSSINADKLTSATNPDKASSMAIAIL
LDKYCYPVVLPKSREVGRDCGAGGEEGDGGERGQREMPNHLKKQFAAIVSTDPLHPLSPE
DKELLWHFRHECMRDPRAYPKLLGSVRWGKQEDVLATHRLLDRSNAWDTSGLDVGLAMQL
LDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKR
IGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGENMLLDFRKQVEMTEALQKVTREMK
AMSADKYDVTQQVVIQLRQKLETLQLSGLPESFRVPYDPGLRAGTLLIEQCKVMASKKKP
LWLQFKRADPTTLSKDPVGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCI
STGNKIGMIEIVKDATTIATIQQSVVGSTGAFKDEILYQWLRDKCVSEEKFQQAVERFLY
SCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPD
FLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEY
IREALTVGRSEDEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRSTFNVQLLI
V
>A0A850UT68|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chloropsis hardwickii|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIETSQSTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQVLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K4XU86|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Regulus satrapa|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKIINSQISLL
IGKGLHEFDSVRDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGS
LQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYTLQ
VNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAACK
PPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGAEMLCKTVSSSE
VSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAWVN
VMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAVNS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIFLAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7L1RBA8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Locustella ochotensis|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPNPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSISAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A4W6FXU5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MDGQQTQVSDEEPKYLREETRRRRRKKAITSSSSASMDQISVEFILPTVARGGNSPDSLQ
LDVAGNWTVEQVKAQVWLKAVTSNLCPEFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVSNSHILVVIHIGTASQTIKVSID
DTPAQVLASFFTKTANKRVLLGIPDNMCEADYVLRVCGREEYLYGDKPLQNFNWIRQCLK
NGEEIHLVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDGKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVVCGKQPQTPNSKGSSYQDNTAGGGSHDGKTKSRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLP
KSRDVGRDVAAVGEDVEGGERGQREMPNHLKKQFAAIVSTDPLHPLSPEDKELLWHFRHE
CMRDPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVR
SMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSMHYQQRYAVLLEAYLRGCGEAMLQDYRKQVEMTEALQKVTREMKAMSADKYDVTA
QVVFQLRQKLETLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPT
TLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKK
SSPHFQKFQK
>A0A7K5G9S3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chunga burmeisteri|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYSFPLQLEPMAKGLGA
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAVKKQATVFRHETVENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGRTPHLTMVHSSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVVS
HPVYYPSFEQLLELGRSGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6F9B0N6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coregonus sp. 'balchen'|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGSIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRPFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRAKMRSFCEERAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDKKATVFRSVRQEKPEDYTLQVNGRWEFIYGKYPLCQFKY
IFSCLRGGQTPHLTMVHYSTIVKYQEEQGCLGSQVSKSRSLSKPPPLPVKKLVVQAGLFH
GSELLCKVVTSGEVNVCSEPLWDQKLVFDISVSDLPRMSR
>A0A669CEU9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MDRQQIQVSDEESQVPREESRRRRRKKAITSSCSNSMDQITVEFVLPTAARGGSGSDTLQ
LDVAGNWTVEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTCKPLPEHLLSKINNGHILVVIHIGTASQTIKVSID
DTPTLVLVSFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLK
NGEEIHLVLEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKQPQIPNSKGSSYQESTAGSSSLDGKTKSRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLP
KSRDVGRDWAVGGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHE
CMRVPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVR
SMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSKHYQQRYAVLLEAYLRGCGENMLQDFRKQVDMTEALQKVTREIKTMSADKYDVTP
QVVFQLRQKLENLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADST
TLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKK
SSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGTISS
>A0A8C8JDT8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPRPSSGELWGMHLMPPSIQVDCLLPNGMILTLVCTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANCNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCGTIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A7F8QNG1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptonychotes weddellii|TrEMBL
MELEHYEQPVVLREDNGRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVPRHAPSEETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCSKAPALSGKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHHQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETE
>M3WP72|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Felis catus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKSNRLARDNELRE
NDKEQLRAICTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYC
LVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYL
DNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQ
VEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLR
LEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQ
NQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKN
KGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKF
GYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMM
LGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQH
ALN
>A0A2Y9GHI7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neomonachus schauinslandi|TrEMBL
MELEHYEQPVVLREDNGRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVQRHAPSEETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCSKAPALSGKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHHQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLYFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7K5AQX5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Furnarius figulus|TrEMBL
MPPGIYCPTEFWSKGENQSIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAARRQQLGWAAWMEYNFPLQLEPVAKAFGT
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPLTLMSYAIKKQATVFRHETLQRPEDYT
LQVNGKWEFLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVTVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAP
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMIFLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C9PIM3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Spermophilus dauricus|TrEMBL
MPLGIDCPMEFWTEVEKNQSVVVDFLLPTGIYLSFPVSRNANLSTIKQMLWHEAQNEPLF
HMLRDPEAYVFTCVNQTAEQQELEDKQQRLCDVQPFLPMLRLVTRQGDRMEKLINSQISL
LIGKGLHEFDCLQDPEVNDFRTKMCQFSEEAAAHRQQLGWEAWLQYSFPLQLEPSTRSWG
DSNTSQISNPDLLVNVKFEGSRESFTIQVSTKDVPLALMACALQKKAKVYQHLTMEQPED
YVLQVNGRHEYLYGSYLLCQFKYICSCLHSGQTPHLTMVHSSSILAMRDEQSKPAPQVQK
PHTKLPPIPMKKPSSVSLWSLGQPFCIELIQGSKINADEQMKLVVQAGLFHGNEMLCKTM
SSLEVSVCSEPMWKQHLEFDINICDLPRMARLCFALYAVMEKAKKVYSRKKKSKKEDCPI
ARANLMLFDYKDQLKTGELCLYMWPSMRKETLEVLNPMGTVHSNPNTESAVTLVIYLPEM
APHPVYYPALEKILELGHHWEHGPTTKEEKLQLQGILEQRGSGELYEHEKDLVWKMRHEV
QEHFPEALAHLLLVTKWNKHEDVAQMLYLLCSWPELPVLNSLELLDFSFPNCHVGSFAIR
SLQKLTDDELLQCLLQLVQVLKYKSYLDCELTQFLLDRALANRKIGHFLFWHLRSEMHVP
SVALRFGLIMEAYFRGSTHHMKVLMKQVEALSKLKALSDFVKVSSQKTTKPQTKELMHLY
MRQDTYLEALSHLQSPLDPSTMLAEVCVERCTFMDSKMKPLWIMYSSEEAGSADSVGIIF
KNGDDLRQDMLTLQMIQLMDALWKQEGLDLRMTPYGCLPTGDCMGLIEVVQHSDTIANIQ
LNQSNLAAMAAFNKDALLNWLKSKNSGDNIMIRENGQVRGTVFSCPVSLSYMPGPGASLT
SLCEACSVAALHSPQLFHIDFGHFLGNFKTKFGIKRERVPFILTHDFVHMIQQGKTSDNE
KFERFRGYCEQAYSILQCHGLLFLQLFALMQAAGLSELSSSKDIQYLKDTLALGKTEEEG
LKHFRVKFNEALRESWKTKVNWLAHNLTKDNRQ
>A0A8C9PGL2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Spermophilus dauricus|TrEMBL
MPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRRKMRIFSEEKIQSLVGLSWIDWLKQTYPPEHEPSTLE
NLEDKLYGGKLIVAVHFENCQDVFSFQVSPEMNPIKINELAIQKRLTIHGKEDEASPYDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECSKIKKMYEQEMIAIEAAINR
NSSNLPLPLPPKKTRVISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TIVSSEISGKNDHIWNELLEFDINICDLPRMARLCLAVYAVLDKVKTKKSTKTINPSKYQ
TIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVASRGGKKFLAVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLSPRDA
LELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALA
NRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLI
KLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPL
WLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGD
RSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCA
GYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A5F8H240|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodelphis domestica|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISHIKQMLW
KQAHSYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKVVTRNCDPGE
KLDSKIGVLIGKGLHEFDALEDPEVMEFRSKMRQFSEEKIQSLIGLSWMDWLKHTYPPEQ
EPSIPENLEDKLYGGNLVVAVHFENCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDE
VDPYDYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPKLTLVECCNIKKMCEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISNVWENTQPFQIVLVKGTKLNTEETVKVHVRAGLFHG
TELLCKPVVSSEISGRNDHVWSEPLEFDINICDLPRMARLCFAVYAVDKVKTKKSTKAIN
PSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDIILHSWSSFPDELEEMLNPMGTVQT
NPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSGNVSSRGGKKFHVVLKEI
MERDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSVKWNKLEDVAQVSSSSIWPKLP
PREALELLDFNYPDQYVREYAVGCLKQMRLVGQKIDEELSQYLLQLVQVLKYEPFLDCAL
SRFLLDRALANRRIGQFLFWHLRSEVHIPAFSVQFGVILEAYCRGSVGYMKVLSKQVEAL
NKLKTLNSLIKLNAMKLNKAKGREAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKC
KYMDSKMKPLRIVYNNKVFGGDPVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRM
LPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDR
AIEEFTLSCAGYCVASYVLGIGDRHSDNIMVRKTGQLFHIDFGHILGNFKSKFGIKRERV
PFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELT
SVKDIQYLKDSLALGKSDEEALKQFKQKFDEALRESWTTKVNWMAHTMRKDYRS
>A0A5F8GLB5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodelphis domestica|TrEMBL
MPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISHIKQMLWKQAHSY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKVVTRNCDPGEKLDSKI
GVLIGKGLHEFDALEDPEVMEFRSKMRQFSEEKIQSLIGLSWMDWLKHTYPPEQEPSIPE
NLEDKLYGGNLVVAVHFENCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEVDPYDY
VLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPKLTLVECCNIKKMCEQEMIAIEAVHVR
AGLFHGTELLCKPVVSSEISGRNDHVWSEPLEFDINICDLPRMARLCFAVYAVDKVKTKK
STKHYPVAWVNTMVFDFKGQLKSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATAL
HIKFPENKKQPYYYPPFDKVSRGGKKFHVVLKEIMERDPLSQLCENEMDLIWTLRQDCRE
NFPQSLPKLLLSVKWNKLEDVAQVTTGSSSIWPKLPPREALELLDFNYPDQYVREYAVGC
LKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLDRALANRRIGQFLFWHLRSEVHIPA
FSVQFGVILEAYCRGSVGYMKVLSKQVEALNKLKTLNSLIKLNAMKLNKAKGREAMHTCL
KQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLRIVYNNKVFGGDPVGVIFKN
GDDLRQDMLTLQMLRLMDLLWKEAGLDLRDDLDRAIEEFTLSCAGYCVASYVLGIGDRHS
DNIMVRKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRF
RQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSDEEALKQFK
QKFDEALRESWTTKVNWMAHTMRKDYRS
>A0A7K5ZPG4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Onychorhynchus coronatus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GSLQTPTKNIFVNVKFQCGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6Q2XXH0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLTSIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFEQVKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESAPELPQH
IYCKLDKGRLIVTIWVIVSPSNSKQKYTLKISHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYVRGCITMGRLPHLMLVSKDSLYSQLPGS
GFVAPSYSRRTPQPSPCPGGGDPSTPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDTLVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKKPCGQLRLTA
FSLSCCSNACHTHRNNSIRLACDSSVSVADGEQLRSLCSRDPLYELSEQEKDFLWRHRHY
CVNIPESLPKLLLSVKWNSRDEWSQMYCLLRDWPLMQPESALELLDCNFPDPMVREFALR
CLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFFWHLKSEMHN
KTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQKTQMKFLVE
HMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWDNPDIMSELLFTNN
EVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVKNSYTI
MQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTRSCAGYCVATFILGIGDRH
NSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQECTKTKEF
ERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKSQQEALE
YFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A6Q2ZEZ6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MAKQVSDEDLHSVVHREENRRRRRKMKAFTSTFSVIMDQISIEFVLPTSTKSSRSPDTLL
LEVAANWTVEQVKAQVWLRAVASNLCPEFYQKFSPDHCILLYQKKGNWCEIYDKHQVFQT
LDCIRYWKALKKDVGKIHLTCRPQPSEDSVRYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLFSPRRIELSDRDPKLYSMDPWITSKPLPDISCLTVTNNHILLVIHKSTASQTIKVSID
DTPVQVLQTFFAKIANKRALLGIPDDMCEADYVLRVCGREEYIYGNHPVRDFHWIRQCLK
NGEEIHLVLESAPNPEQDQVQREDWAQVDDCTGVAGTHEQLTIEEKDHERVFTISLWDCS
RKFRVKVLGIDIPTLPRNPELIVFVEASIFHGQQLLAQERTTSKAFTEEVLWNTWLEFNI
RIRDLPKGSRLSLQVSCGKAQTQPTKGNSSYHEIGAGGGGGHDKTKSRLLYYVNLLLVDH
RSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMALAILLDKYCYPVALPK
SRESKEPGGDGRSAEGGERGLREMPNHLRKQFEAIIETDPLHHLSPEDKELLWHFRQECM
RHPSAYPKLLSSVRWGRQEAVLATHRLLERSTVWDRSPLDVGLAMQLLDCHYSDANVRSM
AVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEI
ATSMHYQQRYAVLLEAYLRGCGDDMLQDFRHQVEMTEALQKVTREIKTMSAEKYDVSAQV
VFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTR
SSDTIGIIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVK
DATTIANIQQSVVGSTGAFKDEILNQWLQDKCVNEEKFQQAVERFVFSCGGYCVATYVLG
VGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSS
PHFLKFQDVCVRAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGHPEEE
AQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVEKRSA
>A0A803SS60|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anolis carolinensis|TrEMBL
MLPGIYCPVEFWSKEANQSIQVDFLLPTGIYLTLSVSCNATLGTIKQLVWHHAQCEPFFH
MLSDPESYVFTCINQTAERQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLISSQISLL
IGKGLHEFDSLGDLEVDDFRVKMQHFCEERAARRQQLSWKAWMEYSFPVQLEPLANGLGG
RSLVNVAIDHFDYFTFQISPKEYPATLMSYAIKKQATVFRHQKINSPEDYALQINGKYEY
LYGNHPLYQFQYIRDCLCRGLLPHLTMVHASSISALWEEQTNGISYPIKAASKAPPVPKK
KLCRSSILPCLPFQLVVQAGLYHGHEMLCKMVSSSEVSVCSEPVWGQRLEFEINVCDLPR
MARLCLALYAVVEKAKKARSTKKKSKKADCPIAWVNVMLFDFRDQLKTGECCLPMWSSFP
DEKGELLNPMGTVQTNPNTESAASLVIRFPTISSNPLYYPTFEQVRSDSITSLWVAVSFP
EAFSPDISPTSMAGILRGCEKQQLKEILERRSHTDLYEHEKDLVWKMRHQIRDQFPHALA
KLLVVTKWNKHEDVAQMIYLLQSWPELPVLNALELLDFSFPDRYVGAFTVNSLKKLTDAD
LFQYLLQLVQVLKYESYLDCELTKFLLGRALSNRKIGHFLFWHLSSQKNAKPQTKEFMHT
CMRQETYLEALSNLQSPLNPSVILAKVSVELCTFMDSKMKPLWIVFNNEDAGGGHVGVIF
KNGDDLRQDMLTLQMIQLMDILWKKEGLDLRMTPYGCLSTGDKTGLIEVVMDSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRE
YCERAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEARRHFQLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A096NGU7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Papio anubis|TrEMBL
MELENYEQPVVLREDNCRRRRRMKPRSVAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVASDFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPAVSSKASAESHSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDTCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A851RN90|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Certhia familiaris|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVRFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKVA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKVQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKTTKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7N4NJD1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sarcophilus harrisii|TrEMBL
MPPGVDCPMEFWSKEENQIVEVDFLLPTGVYLNFPVSRNANLSSIKEVLWHNAQSEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVARQGDRVKKLINSQISLL
IGKGLHEFDSLGDPEVNDFRTKMGQFCEEAAAHRQQLGWEAWMHYNFPLQLEPSARGLGA
GALRGPSRTLFVNVKFEGNEESFTFQVSPNDFPLALMACALKKRVTVFRQPALERPEDYT
LKVNGKYEYLYGSYPLYQFQYICRCLHNGQTPHLTMVHCSSILAMRDEQSNFPAQTPKLR
TKPPPIPMKKPSSVSLWALEQPFCIELIQGSKVNADERMKLVVLAGLFHGNEMLCKTVSS
SEVTVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWSSVPDEKGELLNPMGTVWSNPNTESAAALVICIPEVAP
HPVYYPTMEKILELGKNGEHGRFTEDEMLFLLSSWPELPVLSALELLDFSFPDRHVGSFA
IQSLRKLTDDELFQYLLQLVQVLARVPPDRVTVPAGRPHRKIGRSSLSSEMHVPSVALRF
GLIMEAYCRGSNHHMKALMKQGEALNKMKALNDFVRVSSQRTTKPQTKELMHVCLRQEIY
MEALSNLQSPLNPSTLLSEVCVEQCTFMDSKRSRGSQAAGEAAGSCSPGIIFKNGDDLRQ
DMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSMGDRTGLIEVVSHSDTIANIQLNKSNMAA
TAAFNKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQ
LFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRSYCERAYTI
LRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKVGLGAGARSGLGAPARCPGLSQG
>A0A7J8HTN2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rousettus aegyptiacus|TrEMBL
MPPAMADILDIWAVDSQIASDGSILVDFLLPTGIYIQLEVPREATISSIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRIKMRKLSEEKIQSLVGLSWMDWLKQTYPPEHEPSILE
NLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDEVSPCDY
VLQVSGRVEYVFGDHPLIQFQVCVLTIILREKGVCIYLTI
>A0A2R9B627|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan paniscus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVRPPRPSPCFPGPQPSSVSLWSLEQPFRIELIQGSKVNAD
ERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYA
VIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPT
GTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKLPGGMLLASCEWRPELLWMRLHAEDS
APSRMIGVAMPGLGVLPGLVQAPGDAECSCLLQILELGRHSECVHVTEEEQLQLREILER
RGSGELYEHEKDLVWKLRHEIQEHFPEALARLLWLPTTLTPANPHPDPAAPKPDLGSPQM
LYLLYFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALA
NRKIGHFLFWHLRYSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDF
VKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKP
LWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPT
GDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDF
VHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYL
KDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q3A1Y1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Kryptolebias marmoratus|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFMEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMLKDPEVQDFRRSILSVCREAVEEREGGGAHSQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
SFVPPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVLFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDNSVSAADAEQLRSLCAKDP
LYELSEQEKDFLWRHRHYCINMPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQSLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGETFQEMCYKAYL
AIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKSQQEALEYFTKQMNDAHHG
GWSTKMDWIFHTIRHMPNEH
>A0A3Q2ZM32|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Kryptolebias marmoratus|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFMEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMLKDPEVQDFRRSILSVCREAVEEREGGGAHSQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
SFVPPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVLFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDNSVSAADAEQLRSLCAKDP
LYELSEQEKDFLWRHRHYCINMPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQSLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVRHLHTTQMKFLVE
HMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFTNN
EIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVKNSFTI
MQIQCKGGLKGALQFNSNTLHHWIKDKNRGETYDRAIDLFTRSCAGYCVATFILGIGDRH
NSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQESTKTKEF
ERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKSQQEALE
YFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A3B3D6B6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias melastigma|TrEMBL
MPPAMTDLVDIWGAHSPLDGQAPVHVTMDFLLPTGIYIQMEVPREATIQHIKLLLWKQAK
SYPLSSFLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVFRLVTRNCGRAERLLD
SKIGVIIGKGLHELDGINDQEVKDFRSKMQRLSEERMQRVQMMSFSEWLQACFSPQLEPA
AGTAITDGANDWPADLKVIIHFDQSQDSTSLKVLSSCSPFVLIEIALRKWQTTHAPEEET
KKDQYILRVSQCLEFLYGDHPLIQYKYIRSCLQTKESPHLTLVHINTVKAMFDKESSAIG
AVVSRKSSNPPLPLPPKKRAPTQVQTCVWDVSSPFKVVLVKGSTVNADENAKVQVRAGLF
HGTELLCKPAVKKKSYKNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDMILHC
WSSFPDELEEMLNPIGTVRTNPYPENATALHIHFPEYSSHPIIFPPFDKILEKAAEIAGS
SDSTPIGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVK
WSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVSCLRDMSDEELLQYLLQ
LVQVLRYEPYYDCALTHFLLERAQRNRKIGHFLFWHLRSEIHMPAVSIQFALILEAYCRG
SIPHIEVLKKQVEALSKLKSVNELIKLGTIKNTRSKTKEAMLTKEAMITCLKQSGYSEAL
SDLHSPLNPNVLLSDINVEKCRYMDSKMKPLWIVYNNKLMSSDTLGIIFKNGDDLRQDML
TLQILRLMDLLWKEANLDLRVVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAA
FNKDALLNWLKERNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFH
IDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLVLRK
NGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSDEEALKQFRQKFDEALRESWTT
KVNWMAHNVAKDNRS
>A0A7L1KC97|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rynchops niger|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDHPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQPHESPNADSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIMSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEIWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVRVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3B3C1I5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias melastigma|TrEMBL
MDRRSIQVSDEEPEAPHCRRRRRKKAITPSSCASMDQITIEFVMPSVARGGNSPDVLLLD
VAGNWTVEQVKAQVWMKAVTLNLCPDFYQRLSPDHCILLYQKKGTVCEIYDKHQVFQTLD
CIPYWRALKKGVGRIQMVPRPQPSEESLQYQRYLNCLIGYDVTDVSNVHDDELEFTRRKL
LTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVNNGHILVVIHIGMVSQTIKVSINDT
PSQVLASFFAKTANKRVLLGIPDDVCEADFVLRVCGREEFLYGEKPLQNFNWIRQCLKNG
EEIHLLLEKPPDPELDVVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRK
FRVKVLGIDIPTLPKVPELVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKI
KDLPKGARLNLQVNSTGKGSSHYDNSGGTGKTKNRLLFYVNLLLVDHRSLLRQGEFILHM
WKMPEKSDESSSSINADKLTSATNPDKSSSMAIAILLDKYCYPVVLPKSRDVGRDCGAGE
ETEGGERGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRQECMRDPRSFSCPGKL
LSSMFCGLDVGLAMQLLDCHYSDSHVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHD
SALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGESMLQDFRK
QVEMTMALQRVTREVKAMSADKYDVSAQVVFQLRQKLETLQSSGLPETFRVPYDPGLRAG
ALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQDMLILQILLIMESI
WETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQRVVGSTGAFKDEILHQWLRDK
CVSEDKFQQAVERFLLSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKS
FMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFLKFQDVCVKAYLALRHHTNLLIILFSMM
LMTGMPQLTSKEDIEYIREALTVGRSEEEAQRHLLDQIEICREKGWMVQINWFVHLVLGI
KQGVEKRST
>A0A4W5LU45|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MLAACLYRLSPMVWRNASSEPLYGALSDADAYVFTCINSTAEREELEDETRRLCDVRLFM
SVLRLVAREGDRVEKLTNTQISLLIGKGLHEFDTQKNHEVNEFRAKMRSFCEEKAQDRQR
LPWYQWMEYSFSCDLEPCVSLPEPGGNKTKGTKKIFVNVKFEASDVSALFLWPFLLLFLM
FVLVNQSVTFLRQEKPEDYTLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHS
TVVKYQEEQGCLGSQVSKSRSLSKPPPLPVKKVRGQPLGTTLVVQAGLFHGSELLCKVVT
SCEVNVCSEPLWDKKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPLA
WVNTMVFDYKDQLKTGEFLLSTWPSVPGDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHP
LYYPHFDKGPRKKWREGYSHQGGGKGLSILKEIVDNKNYTEFFEDEKELLWKLRGVVRER
YPESLSKLLLITKWNKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLR
KLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHVSSVS
LRFGLILEAYCRGNIYHIKNLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQ
EAYMEALSYLLSPLNPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIFKNGD
DLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNS
NSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIK
ETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQ
AYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNEA
LRESWKTKVNWMMHSLAKDSRL
>A0A7L1C5J1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Illadopsis cleaveri|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHAKTPEILLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKISNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C2XNN2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MDVPREATIQHIKLLLWKQAQSFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDIR
PFLPVLKLVTRNCGRAERLLDSKIGVLISKGLHELDAINDQEVKDFRSKMFRLSEERMQQ
VQMMTCTEWLQACFSPQLEPPAGTAITDGLNDRPADLKIIIHFDQSQDSASLKVPSSCVP
SELMELALKKWLTTHGPEEEEAWRGQYVLRVSSLPPHPPPPPPVEYIFSHAALASSSLQQ
VQTCVWDVSSSFKIVLVNGSKVNAEETAKVNVRAGLFHGTELLCKPAVSSESSGRSDHTW
KDSTLEFDLSVCDLPRMTRLCFAIYAVMDKVKKQKSTKNHYPIAWVNTMVFDYKGQLKTG
DIILHCWSSFPDELEEMLNPIGTIQTNPYTENATSLHINFPEYSSHSIVFPPFDKVRVLS
HFFLFAGIRASAHFLFCCFLQILEKGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLR
YDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREY
AVGCLRDMSEEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGNRKIGHFLFWHLRSEI
HMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKTARSKTKEAM
LTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGINVERCRYMDSKMKPLWIVYNNKLLG
GDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSS
ADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALERAIEEFTLSCAGYCVATYVLG
IGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYT
EKFGSFRQYCEEAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDED
ALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C7UYA9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
IELQVSDEEESQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFN
IRIRDLPKGARLSLQISKGTSSYQDNGGSPVGGGSGSHDCNKTKSRLLYYVNLLLVDHRS
LLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYPVALPKSR
EGERGQREMPNHLRKQFEAIVETDPLHPLSQEDKELLWHFREECMRHPRAYPKLLGSVRW
GRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLETLGDDDVLR
YLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLE
AYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQVVFQLRQKLENLQTSG
LPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTTLSSDTIGVIFKDGDDL
RQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSVVGS
TGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLGVGDRHNDNIMITESG
NLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVRAYL
ALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEEAQRHLLDQIEICRDK
GWTVQFNWFLHLVLGIKQGVDKRSA
>A0A8C5PBF4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptobrachium leishanense|TrEMBL
MPPAVLDPMDIWAVDAQLHSEISVDVLLPTGIYVQMEVRRDASISHIKQLLWKHAPSYPL
YHLLLEMDSYMFECVNQTAVHEELEDETRRLCDVRPFLPVLKLVSRNCNPAEKLDSKIGV
LIGKGLQEFDALNDNEVKEFRSKMRKISEDKAQSLLRLTWMEWLKCTFPPELEPCVQENI
QDKLYSGNLVVAIHFDNCQDVFSFQVSPNMTPTKVNELAIRKRLTIHGREEEEVDPEDYV
LQVSGRQEYVFGDHPLIQFQYIKSCVMNKSLPRLILVECCNIKKMFDQEISAVELAVKRK
TTGPPLPLPPKTRASVVVRAGLFHGTELLCKPMSAELSGKSDSLWNAPVEFEINVCDLPR
MARLCLAIYTVDKTQKKKGNKTGNPKYQTIKKAGKMHYPVAWVNTMVFDYKGQLKAGEHV
LHGWSSFPDELEEMLNPMGTVRTNPYIENATALHIKFRDHAKAVYYPPFDKILEKAAEIA
RHSDSLTMSGRGGKKFNIELKEIMERDPLCQLCENEKDLIWTLRYDCRENFPCSLPKLLL
SVKWNKLEDVAQLQALLQIWSKLPPRDALELLDFNYPDQYVREYAVNCLKNMSDEELSQY
LLQLVQVLKYEPFLDCALSRFLLQRALANRRIGQFLFWHLRSEVHISTVSVQFGLLLEAY
CRGSVAHMKVLSRQVEALNKLRTLNSLIKLNAMKQSKVKNKESMHACLKQNAYKEALTDI
QSPLNPSVTLSELVVEKCKYMDSKMKPLWIVYSNRGFGGESMGIIFKNGDDLRQDMLALQ
LLRLMDMLWKESGLDLRIVPYGCLATGDRCGLIEVVSAAETIADIQLDCSNLAAAAAFNK
DALLNWIKEFNAGDDLERAIEEFTLSCAGYCVATYVLGIGDRHNDNIMVRKTGQLFHIDF
GHILGNFKSKFKIKRERGPFILTYDFIHVIQQGKPGNTEKFGRFRQYCEDAYLILRRNGN
LIITLFALMLTAGLPELSSVKDIQYVKDSLALGKTEDDALKQFRQKFDEALKESWTTKVN
WMAHTVRKDYNKS
>A0A087Y3F9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia formosa|TrEMBL
MDRQQIQVSDEEREVAREESRRRRRKKAITSASSTSMDQISVEFVLPTVARGGSSPDSLL
LEVAGNWTVEQVKAQVWMKAVSLNLCPDFYQRFCPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPTDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPNLYSMDPWVTRKPLPEHLLSKVNNGYILVVIHVSTSSQTIKVSID
DTPSQVLASFFAKTANKRVLLGIPEHLSDEDFVLRVCGREEYLYGEKALQSFNWIRQSLK
NGEEIHLVLETPPDPELDLVQREDWAQVDDCTGVAGTHEQLTIAEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPEFMVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKQPQTPNSKSSYHDNTSGSSTLEGKTKNRLLYYVNLLLIDHR
SLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPK
SREVGRDCGAGSEEGDGGERGQREMPNHLKKQFAAIVSTDPLHPLSPEDKELLWHFRHEC
MRDPRAYPKLLGSVRWGKQEDVLATHRLLDRSNAWDTSGLDVGLAMQLLDCHYSDAQVRS
MAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGENMLQDFRKQVEMTEALQKVTREMKAMSADKYDVTQQ
VVIQLRQKLETLQLSGLPESFRVPYDPGLRAGTLLIEQCKVMASKKKPLWLQFKRADPTT
LSKDPVGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIV
KDATTIATIQQSVVGSTGAFKDEILYQWLRDKCVSEEKFQQAVERFLYSCGGYCVATYVL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKS
SPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSED
EAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A8C2TQ33|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coturnix japonica|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGAIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLSHTPVKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQVSLLSCFDKRVCPPCTHFSGRVVDGSADEMSSARQVTFLA
MPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSS
EVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWV
NVMLFDYKDQLKTGECCLHMWSSFPGMSGANRWDLPLTYCPLYALCCDSHEQKLQLKEIL
ERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLTITKWNKHEDVAQMISLLQTWPELP
VLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLD
RALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKAL
NEFVKLSSPKATKPQAKEMMHVCMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSK
MKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
STGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCEKAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQ
YLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C5R828|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptobrachium leishanense|TrEMBL
MMESHDFFKEPEVIIVHMLHLLLSKQQYKIASGMELDNNDQPVVLRDENKRRRRKMRPHS
ATINIFSMELIPIEFILPTSHKNNKAPDTILLEIAGNCTVEQMKAQVWMNAIEKSHNSDF
YHRLAPDQFLLQYQKKGQWYEIYDKHQVIQTLDCIVYWKVLKKTVGKIYVVQKEKNSDET
LEYQKQLNYLIGYDVTDVSNVHDDELEFTRRRLVTPRMIELAKRDARLYSMDPWVTSKFL
PEYLGRKISSNTIFIIIHKGMTSHTVKVSINDTPDEILQSFFTKMAKKKSLLDISEENSE
LDFVLRVCGRDEYIFGNTPIKDFHWIRQCIKNGDEIHLVLDAPPDPTDDKVQKEEWPLVD
DCTGVTGYHEQLTIEEKDHEKIFTISLWDCNRKFRVKVIGIDIPVLPRNSELTVFVEANI
QHSQQLLAQKRTTSKPFTEEVLWNTWLEFDIKIKDLPKGALLNLQIFCGKAVTPSNKTSL
QSPDSSSSDSKCKNQLLYYVNLLLIDHRFLLRQGEYVLHMWKIPGKGEEQGSINADKLTS
ATNPDKDTSMAISISLDKYCHPVALPKNKSVVDAEQDRSRGEMPNQLRKQLEEIMATDPL
HPLTPEDQELLWHFRYEIIKHPEAYPKLFTSVKWGQQEIVTKTYQLLSKREAWDDCSLDV
GLTIQLLDCNFSDENVRAMAVQKLDSLPDDDVLHYLLQLVQAVKFEPYHDSSLSRFLLKR
ALRSKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGTAMLKDFMKQVQVTELLHK
VTMEIKSLSAEKYDVTSQVITQLRQKLEKLQGSKLPESFRVPYDPGLRAGLLMVEKCKVM
ASKKKPLWLEFKCADPTALTNETIGIIFKHGDDLRQDMLILQILRIMGSIWEAESLDLCL
LPYGCISTGNKIGMIQIVKDATTIAQIQQSTVGNTGAFKDEVLSQWLKEKCPLEEKYNAA
VERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVP
FVLTPDFLYVMGTSGKKTSLYFHKFQDVCVKAYLALRHHSNLMIILFSMMLMTGMPQLTS
KEDIEYIRDSLTVGKNEESAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A5N5LWZ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pangasianodon hypophthalmus|TrEMBL
MGPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDSEVQDFRRSILSVCREAMEEREGGGPHTHALYVYPPSVESSPQLPQH
IYAKLDKGRLIVTIWVVVSPSNAKQKYTLKIAHDCVPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGKLPHLMLVSKESVYDQLPCS
GFVTPSYSRRTPQPSPSPGVGDPANPRSLWTFNAHTLLRIRLICATYVNVNIRDIDKIYV
RTGIYHGGEPLCDNVNTQRVPCSNPR
>A0A670YII7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pseudonaja textilis|TrEMBL
MRYCRLSLPPAKSSILISSRLTQPSIGWQNEDPPSTWYISLRLLLSSFQVVWHQAQYEPF
FQMLSAPDSYVFTCINQAAELQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLLNSQIS
LLIGKGLHEFDSLADPEVNDFRVQMQDYCEQKAAQRQQLSWKDWMEYSFPVQLEPALSGL
GRRPSLPMPGKTIFVNVKFQSGGVNNLYAVKKQATIFRHQRVSPADEYTLQVNGKYEYIY
GEYPLYQFQYIRECLHRRFVPHLIMVHRSSLLTLREEQSNGLGHPPKTNWIGSSLGWINL
LPSPIYLLFFQLVVQAGLYHGHEMLCKMMTSTEANVCSEPTWDQTLKFDIHVCDLPRMAR
LCLVLYSVVEKAKKARSTKKKSKKADCPLAWVNVMLFDYQDQLKAGECVLPMWSAFPDEK
GELLNPTGTIQTNPNAESAATLFIRFPGISLYPIYYPSMRQVRLLKEILERRSCIELYEH
EKDLVWKMRYQIRDQYPGALAKLLMVTKWNKHEDVAQMIFLLQSWPELPVLNALELLDFN
FPDPHVSRFTVNSLKKLTDAELFQYLLQLVQVLKYQSYLDCELTKFLLGRALSNRKIGHF
LFWHLRSEMHFPSLALRFGLILEAYCRGNADHIKALMKQSEALNKLKALNDLIKVSAQKN
TKPQTKEFMHTCMRQETYLEALSHLQSPLDPRIFLARVSVELCTVMDSKMKPLWIMFNNG
EAGGPNTGLIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKMGLIEV
VMNSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATY
VLGIGDRHSDNIMVRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKT
SNSEKFERFRDYCERAYMILRGHGLLFLHLFSLMKAAGLPELSCSKDIQYLKDSLALGKT
DEEARKQFHLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A835NPV7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lamprotornis superbus|TrEMBL
ESVMNADGNAVQQGKEMSSLESPVWEAVPSSLSDLGGAPKDDAGMFLTYLESLLVFMVDS
LDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSYPLFHLLME
IDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKIGVLIGKGL
HEFDALQDPEVNDFRAKMRRISEEKIQSLDVFSFQVSPNMNPIKLNELAIRKRLTIHGKE
DEEVDPADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEM
IALEAAINRKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNRLNTEENAKVHVRAGL
FHGTELLCKTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKST
KAMNPSKYQTIRKAGKVHYPVAWVNTMVFDYKGQLRSGELVLHSWSSFPDELEEMLNPMG
TVQTNPYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYV
VLKDIMERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQ
IWPKLLPREALELLDFNYPDQYVREYAVGCLRQMRRARNSERNILITKGEIFLESNTVTP
GTQPPPLWLYHLMSCSIDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQML
FWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAMKQS
KAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKPLWIVYNNKM
FGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATGDHSGLIEAV
SSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLSCAGYCVATYV
LGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTG
NTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSE
EEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A822HB79|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ranitomeya imitator|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPID
SFTMPSYSRRISTATPYMNGETATKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A670YFS5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pseudonaja textilis|TrEMBL
MPPGMYCPSEFWSKESNYTIHVDFLLPTGIYLPLPVSCHASLAAIKKVVWHQAQYEPFFQ
MLSAPDSYVFTCINQAAELQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLLNSQISLL
IGKGLHEFDSLADPEVNDFRVQMQDYCEQKAAQRQQLSWKDWMEYSFPVQLEPALSGLGR
RPSLPMPGKTIFVNVKFQSGGESFTFQISLKEFPITLMSYAVKKQATIFRHQRVSPADEY
TLQVNGKYEYIYGEYPLYQFQVLHPRMPPPAFRPPPHYGPQILSSDFLTCVSLWSLDQPY
YIELLHCSKVNADEGMKLVVQAGLYHGHEMLCKMMTSTEANVCSEPTWDQTLKFDIHVCD
LPRMARLCLVLYSVVEKAKKARSTKKKSKKADCPLAWVNVMLFDYQDQLKAGECVLPMWS
AFPDEKGELLNPTGTIQTNPNAESAATLFIRFPGISLYPIYYPSMRQVRLVLMCSLHLSW
ENSVQLPLLSLCVCVLLFQILEKGQNGHCACGTGEDPEEQLKEILERRSCIELYEHEKDL
VWKMRYQIRDQYPGALAKLLMVTKWNKHEDVAQMIFLLQSWPELPVLNALELLDFNFPDP
HVSRFTVNSLKKLTDAELFQYLLQLVQVLKYQSYLDCELTKFLLGRALSNRKIGHFLFWH
LRSEMHFPSLALRFGLILEAYCRGNADHIKALMKQSEALNKLKALNDLIKVSAQKNTKPQ
TKEFMHTCMRQETYLEALSHLQSPLDPRIFLARVSVELCTVMDSKMKPLWIMFNNGEAGG
PNTGLIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKMGLIEVVMNS
DTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGI
GDRHSDNIMVRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSE
KFERFRDYCERAYMILRGHGLLFLHLFSLMKAAGLPELSCSKDIQYLKDSLALGKTDEEA
RKQFHLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7N6AED2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPGKYGMQGEWEKEGDHEIMMDFLLPTGIFLKFPVSRNDTIKTIKRMVWKNARSEALFT
ALGDPDAYVFTCINHTAEREELEEESRRISDVQPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEVQKNHEVNEFRTKMRVFCEEKAQERQRLPWHQWMEYSFPCDLEPCCSPQCG
SSRSKNTKKILINIKFEASDVSRSTDVDPQDPPLVLMRSALKKKATVFRSVRQEPEDYTL
QVNGRWEFIYGNHPLCQFKYIFSCLRNGQNPHLIMVHHSTISKYQEEQGRMCNQVYKSCS
LSRPPPLPLKKVRGQRTVASACVFPLQLVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQ
KLEFDINVADLPRMGRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLK
TGEFLLSTWPSVPDDKSDLLNPMGTVERNPNVDSAAGLLIRFANIRPYPLYYPPLDKVLV
LKTLYQSLKCLFVLLCQKQTKSFVKLKEIMDNKNYTEFFEDEKELLWKLRAEVRSSYPES
LSKLLLITKWNKREDVVQMVSLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLRNLSD
DELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVSLRFG
LILEAYCRGNIHHIRLLTKQNEALAKMKSLSDFVKSGSQKMTVEDLKLCIRQESYLEALS
DLLSPLNPSIILSGICADKCRFMDSKMKPLWLMYKNPGTQGDMVGIIFKNGDDLRQDMLT
IQMIQLMENLWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNCSNSAATAAF
NKDALLNWLKSKNPGDKLDQAIEVFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHI
DFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRN
GTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLCLGKSDDEALKNFKVKFNEALRESWKTK
VNWMMHSLAKDNRP
>K7FEW9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pelodiscus sinensis|TrEMBL
MELGNYEQRVVMREENKRRRRRMKPFSAASNLSSMELIAIEFILPTSNKHTKVPETMILE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHKFTPDQCILQYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGKIYVIQKQNPTEVVQEFQSQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYSMHPWITSKPLPEYVFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPVKDFHWIRQCLKNG
EEIHLVLDDPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIVGIDIPVLPRNTELTVFVEANIQHGQQLLSQRRTTSKPFTEEVLWNTWVEFDIKI
KDLPKGALLNLQIYCGKAQALSTKATIQSHDSPNSESKCKTQLLYYVNILLIDHRSLLRS
GEYVLHMWKISGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEAIIDTDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVSKTYQLLAKREAWDHSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQIIKLLHKVTMDIKSVSAEKYDVTAQVITQLKQKLEKLQNS
KLPESFRVPYDPGLRAGTLVIEKCKIMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQKAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTAGKKTSLHFHKFQDICVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKNEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8J5ZXP8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Galemys pyrenaicus|TrEMBL
MPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISFIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWIDWLKQTYPPEHETSILE
NLEDKLYGGKLIVAVHFENCQDVFSFQVSPAMNPIKINELAIQKRLTIHGKEDEVRPNDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFTLVECCKIKKMYEQEMIAIEAAINR
NSSNIPLPLPPKKTRIISHVWENNNPFQILLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TIVSSEISGKNDHIWNEPMEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQ
TIRKAGKVFKNNLLKNQNYFHVLEELEEMLNPMGTVQTNPYTENATALHIKFPETKKQPY
YYPPFDKIIEKAADIASSDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQ
DCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYA
VGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVH
IAAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMH
TCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVI
FKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADI
QLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSD
NIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFR
QCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQ
KFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7L0Z155|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ploceus nigricollis|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRSKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPLAKGLGT
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEMLQLKEILERRSHTELYEHEKDLVWKMRYE
IRDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGVGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>H2YGB1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ciona savignyi|TrEMBL
EEESIYDEWGYHNSLNVSVDFFLPTGIYIPLDIPRNYTIKQVKHVLWEEAIHYPLFSKLL
NPESYIFTYITSFGLTEEIVDELRHLSEVRIDFHWSTPLVGYQIVTMKKLMSAEILLNIS
DDNELNIDHESSSFRKDMREMAIQVSKQRDALHWKVGTIYCSWLFFHVTKIRQFLNVLIS
TSVINTNFLSIFMTVYTIKINPGWTTDTLTREALAAWRQKTKSRLPSDNDDDYVLKGGGK
EYLVGNHPIYMFKFLRKALVCRQLTPNVTTFNNSSYLSKTDDDLNKTDSSSFQNNLAPPV
PEKHRPVWSLWQLDVMFKLRVIRAGNVNAAQERDKKLVIHIGLYHGSETLCPTTYTKEPV
KETAAGDMRNEYQWDEECFFDINAVNLPRNAMLCFAVCSSKRGVGGKTKKDKKKYIQAAT
PIAWVNMMVFDFKRFLKAGLYRLNCWPVNLDNLDSNNLFPRGGLMTNPDVEQATFIEIAM
TEYQAAIMYPSLPEVREAARQAVVRESNLMTSAASKLHMTQLEEVIRKDRFDDLYDDDKS
LLWRLRIDCREHFPDALSKVLASANWSSYKSVAMVQAMLNSWKPLSPEHAMELLDSQYAD
EHVRDFAVKCLESLRDDELQQYLMQLVQVLKFDSYLSSSLVRFILRRAWNNRKIGHFLFW
HLKSEISQKTLNLRFSLILEAYLYGNLPHMKTLCKQHEALNKMRTLNDRVSFSPKDIKVR
ARQALKDTANQDSFREALTSVECPLEPNIDMQELLVDKCKVMNSKMRPLWLVFKNSDMQD
GSIAVIYKNGDDLRQDMLTLQTISIMDVLWKSEGLDLRMIPYGCLATGEGTGMIEVVTHA
NTIANIQKTRGGKMAAFRHQTLIEWLEQNNTTKSEFDQAIENFTYSCAGYCVATFVLGVG
DRHSDNIMVTEKGQLFHIDFGHILGNFKTKFGIKRERVPFVLAHDFVHVINKGKNNNKAD
FDKFRKLCDNAFCILRRKGYLFITLFALMVHSGLPELNSLDHLEYLRETLALHLTEQKAL
QQFRSKFNKALTDAWATSVNWFFHNVTRDNT
>A0A6J2VNV2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chanos chanos|TrEMBL
MPPAMTDQLDMWADSGLDGDDQVLVDFLLPTGIYIQMEVPRESTIQHIKLLLWKQAQEYP
FFSLLGEMEGHMFECVNQAAVHEELEDESRRLCDVRPFLPVLKLITRNCGRAERLLDSKI
GVLIGKGLHELDALQDPEVKDFRLKMQRMSEEKMQHAQMMSWREWLMSYFSPPLEAGPVN
GLIDKAETIKIIMHYDQSQDTASLKVSVSCTVMELMEVAYRKWLTTHGPEEDGSYLGDYV
LRVSSKLEFLFGEQALVQYKYIRSCLLAQECPHLTLVHCSVVKSMFEREMSVIGAVLPRK
SSNPPLPLPPKKRGQSMQLQQQTCVWDVHTPFRITLVKGIKVNAEETAKVQVRAGLFHGT
ELLCKPAVSSESSGRTEHVWNRMMEFDIPVCDLPRMTRLCFAIYAVMDKVKKQKSTKNTH
LNKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHTWSSFPDELEEMLNPIGTVQT
NPYTENATALHFSFPEYSSYPVIFPPFDKILEKAADIAGSSDSVPMVGRGGKKFHIELKE
IMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWNKHEDMAQLQALLQIWPK
LSPRDALELLDFNYPDQYVREYAVNCLRDMSDEELSQYLLQLVQVLRYEPYYDCALSRFL
LERAQNNRKIGHFLFWHLRSEIHMPAVCVQFALILEAYCRGSIPHIEVLKKQVEALSKLK
AVNELIKLGTIKAKTKTKELKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGVHVEKCRY
MDSKMKPLWIVYHNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVP
YGCLATGDRSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKEKNSGDALEKAI
EEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPF
ILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSV
KDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAHRS
>A0A672LAQ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLVCLLWKEAQT
YPLFSLLGEMEGHMFECVNQAAVHEELEDGTRRLCDVRPFLPVLKLITRNCGRAERILDS
KIGVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYSMPLEAGS
LENLIDKHEGIIKITMHYDQSQVSSVNLSYDSLISFSLFRTQPALKKWQTTHCPEEDIGF
RSDYVLRVSGKLEFLFEDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIGS
VLARKTSNPPLPLPPKKRLPTASTLFPALQLMQGVLSFAYLAVRAGLFHGTELLCKTAVS
SESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIPW
VNTMVFDYRGQLKTGDIILHCWTSFPDELEEMLNPIGTIQTNPYTENATELHIINNSMLG
QTAIESLSLWFAGVVPNSAPLPISTLLKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQ
SLPKLLLSVKWSKHEDMTQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVYCLRDMS
DDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMFMPAVSVHF
ALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFGTIKTKTKQAHLKEAMMTCLRQT
GFIETLSDLHSPLNPNILLAGINVERCKYMNSKMKPLWIVYNNKLLEGDTVDIIFKNGDD
LRQDMLTLQILRLMDLLWKEAKLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQKTSSN
MAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRS
TGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTSNTEKFGNFRQYCEEA
YLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEAL
RESWTTKVNWMAHIVAHPS
>A0A672LIG2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDGTRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYSMPLEAGSLE
NLIDKHEASLKVSLHCTVTELMDQALKKWQTTHCPEEDIGFRSDYVLRVSGKLEFLFEDH
PLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIGSVLARKTSNPPLPLPPKKRL
PTASTLFPALQLMQGVLSFAYLAVRAGLFHGTELLCKTAVSSESSSRSEHVWNKTLEFDI
AVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIPWVNTMVFDYRGQLKTGDIIL
HCWTSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVFPAFDKHVFYKQHLT
CLRFTWQLKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMTQ
LQALLQIWPKLSPRDALELLDFNYPDQYVREFAVYCLRDMSDDELLQYLLQLVQVLRYEP
YYDCALSRFLLERAQSSRKIGHFLFWHLRSEMFMPAVSVHFALILEAYCRGCIPHIEVLK
KQVEALSKLKAVNELIKFGTIKTKTKQAHLKEAMMTYLCVCTYMNSKMKPLWIVYNNKLL
EGDTVDIIFKNGDDLRQDMLTLQILRLMDLLWKEAKLDLRIVPYGCLATGDHSGLIEVVS
SADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVL
GIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTSN
TEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDE
EALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A226PR53|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Colinus virginianus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVSNILTASSLCRSEMHNKTVSQR
FGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPD
FMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKN
GDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCK
GGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMV
KDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEM
CYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQM
NDAHHGGWTTKMDWIFHTIKQHALN
>A0A452EUC1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Capra hircus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7N8XDW0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPAMTDLLDIWAAHSPLAGQAPAHITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINEQEVKDFRSKMFRFSEERMQRVQMMTCTEWLQSCFSPQLEPA
AGSAITDGVNDRPSDLKVIIHFDLSQDSISLKVPSSSTTMELIELAVRKWLTTHGPEEET
RRGQYVLRVSHCLEFLCGDHPLTHYKYIRICMQAKESPHLTLVHISTIKGMFDKEISTIR
AVVTRKSCNLPLPLPPKRRVPTQVQTCVWDVSSPFKIVLVNCSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESSGRSEHTWKESTLEFEISVSDLPRMTRLCFAIYAVMDKVKKQKST
KNAYINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHILFPEYSSHPIVFPPFDKILEKAAEIAGASDCAPMGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLSPRDALELLDFNYPDQYVREYAVCCLRDMSDEELLQYLLQLVQVLRYEPYYDCALT
HFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRCNIPHIEVLKKQVEALS
KLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVMLSDI
NVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAS
LDLRIVPYGCLATGDRAGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSG
DALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKSDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A673TRE0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Suricata suricatta|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
DAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAIYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYAENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPRDALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7N8XH69|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSRNDTIKVIKKLVWKNARSEALFT
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTRMRQFCEEKSQERQMLPWQQWMEYSFPCDLEPCCSLPST
KSRNTKKIFINIKFEACDVSQDPQDLPVALMKSALKKKATVFRSVRLEPEDYTLQVNGSW
DFIYGKHPLRQFKVSDLKEQDFIGKSDCVCLFTFQLVVQAGLFHGSELLCKVVTSSEVTV
CSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKPFYLYITARKEG
IAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFPN
IRPHPLYYPPLEKVLTPYKLKEIMDNKNYTEFFEDEKELLWKLRYEVCSLYPESLSKLLL
ITKWNKREDVVQMVGLLRNWPDLPAIHALELLDYSFPDPAVRFFTIRCLKKLSDNELLQY
LIQLVQVLKYESYLDCDLTTFLLERALANRRIGHFLFWYLRSEIHVASVSLRFGLILEAY
CRGNIHHIKLLTKQNEALGKMKILSDIVKQESYLEALSDLLSPLNPSIILAEICAHKCRF
MDSKMKPLWLMYGNPWAQGEMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMSP
YGCLSTGNKMGLIEAVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDQAI
EEFTLSCAGYCVATYVLGIGDRHNDNIMIRENGQLFHIDFGHFLGNFKRKLGINRERVPF
ILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGMLFVNLFAMMKAAGLPELSSF
KDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A3Q2W2T5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Haplochromis burtoni|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKSIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRAFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKTKNSKKIFINVKFEASDESFMLQQDPHDLPLVLMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNSQNPHLTMVHYSTVTKCQEEQGRMCNQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPCVPDEKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKICDMERNGDLSLATKDEYFKLKEFMDNKNYTEFFEDEKELLWKLRTEVRD
HYPESLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCL
RKLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASV
GLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESY
LEALSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLR
QDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSA
ATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYK
ILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDNRP
>A0A6P8TP44|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gymnodraco acuticeps|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVEMRDASGPHSRALYVYPPNIESTQELPKH
IESKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKIYVRTGIYHGGEQMCDNVNTQRVPCSNPR
WNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNINMFDYTHTLVANKMA
LNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSSLVKYPEMNAVEDHANWTISR
ELGFNYNLSGQSNRSARDHALTDSDTEQMRQLSNRDALSEITEQEKDFLWRHRHYCMNIP
EILPKILLSVKWNSRDEVAQMYCLLKEWPSTRPEQAMELLDCNYPDPMVRHFAVRCLEKY
LTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQ
RFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMRFLVDQMKRP
DYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFK
NGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRSSHTIMQIQC
KGGLKGALQFNSNTLHQWLKDKNKGEMYDLAVDLFTRSCAGYCVATFILGIGDRHNSNIM
VKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECAKTKEFERFQE
MCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKSEQEALDYFMKQ
MNDAHHGGWTTKMDWIFHTIRQHALN
>A0A3B5QBX4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xiphophorus maculatus|TrEMBL
RGGEDIDEEREVAREDSRRRRRKKAITSASSASMDQISVEFVLPTAARGGSSPDSLLLEV
AGNWTVEQVKAQVWMKAVSLNLCPDFYQRFCPDHCILLYQKKGTVCEIYDKHQVFQTLDC
IRYWRALKRDVGRIQLAPRPQPTDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLL
TPRRIELSDRDANLYSMDPWVTRKPLPEHLLSKVNNGYILVVIHVSTSSQTIKVSIDDTP
SQVLASFFAKTANKRVLLGIPEHLSDEDFVLRVCGRYEYLYGEKALQSFNWIRQSLKNGE
EIHLVLETPPDPELDLVQREDWAQVDDCTGVAGTHEQLTIAEKDHERVFTISMWDCNRKF
RVKVLGIDIPTLPKVPELTVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKIK
DLPKGARLNLQNPLSSRLFVCLSGKTKNRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEK
SEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSREVGRDCGAGGEEGDGG
ERGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVKWGK
QEDVLATHCLLDRSNAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYL
LQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAY
LRGCGENMLQDFRKQVEMTEALQKVTREMKAMSADKYDVTQQVVIQLRQKLETLQLSGLP
ESFRVPYDPGLRAGTLLIEQCKVMASKKKPLWLQFKRADPTTLSKDPVGIIFKDGDDLRQ
DMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIATIQQSVVGSTG
AFKDEILYQWLRDKCVSEEKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNL
FHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGW
MVQINWFVHLVLGIKQGVEKRST
>A0A8D1YWM7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQKLESLEDDDVLHYLLQLVQAVKFEPYHDSAL
ARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQ
VIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLPQSFRVPYDPGLKAGALV
IEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWET
ESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLSHWLKEKCPI
EEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLG
INKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMT
GMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQG
EKHSA
>A0A851LCD2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Corythaeola cristata|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAVKKQATVFRHETVENPEDYT
LQVKGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKMA
PKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKTLNDIVKMSSQKATKPQTKEVMHV
CMKQETYLEALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A341CRG8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neophocaena asiaeorientalis asiaeorientalis|TrEMBL
MKGDPEKRKSLEAHWVAEGMELETHEQHVVLREDNRRRRRRMKPRSAAASLSSMELIPIE
FVLPTSQRNTKTPETALLHVAGHGNVEQMKAQVWLRALETSVAADFYHRLSPDHFLLLYQ
KKGQWYEIYDKYQVVQTLDCLRYWKVLHRSPGQIHVVQRLAPSEETLAFQRQLTALIGYD
VTDVSNVHDDELEFTRRRLVTPRVAEVAGRDTKLYAMHPWVTSKPLPECLLKKITNNYIF
IVIHRSTTSQTIKVSADDTPGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYL
VGETPIRNFQWVRQCLKNGEEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTI
HGKDHESVFTVSLWDCDHKFRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSP
KPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLL
YYVNLLLIDHRFLLRHGEYVLHMWQLSGKAEDHGSINADKLTSATNPDKENSMSISILLD
NYCHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYE
SLKDPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCSFSDENVR
AIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRS
EIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIDMLQKVTMDVKSLSAEKYDVSS
QVISQLKQKLEILQNLNLPQSFRVPYDPGLKAGALVIERCKVMASKKKPLWLEFKCADPT
ALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEI
VKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFV
LGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKK
TSRHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSE
EDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>G1QWH0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nomascus leucogenys|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMHKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMRYLLAKFKEGKRLMGDEELSQYLLQLVQVL
KYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHM
KVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCV
ILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLL
WKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLK
EYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFK
SKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFAL
MLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRK
DYRS
>A0A6G1B7K7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crocuta crocuta|TrEMBL
MCFSFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPCILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMSPIKINELAIQKRLTIHGKEDE
VSPSDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAIYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K5JU92|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mionectes macconnelli|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPVTLMSYAIKKQATVFRHEMLQKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>D2I0M7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ailuropoda melanoleuca|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSVLENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPETKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C4I9F3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MPPGKYGMQEEWEKEGDQGILMDFLLPTGIFLKFPVSRNDTIKSIKKMVWRNARSEALFS
GLGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPMS
GSMKSKSTKKIFINVKFEACDESFMLQQDPQDFPVALMRSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGKHPLCQFKYIFSCLRNGQNPHLTMVDHTTISKYQEEQGRMCSQVYKSR
SLSRPPPLPLKKNTSSLWSINEPFYINLVQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SPEVAVSSEPLWDQNLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFHNIR
PHPLYYPPLDKVHIPKRQKHILKAIFVSQSYMKLKEIMDNKNYTEFFEDEKELLWKLRTE
VRNHYPESLSKLLLITKWNKREDVVQMVSLLRKWPDLPAIHALELLDYSFPDPAVRSFTI
RCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLSERLQP
FGKHSPHQALNQTGNLTHLYTLTSSSEMCVFNEALGKMKALSDFVKSGSQKMTVDDLKLC
IRQESYLEALSDLLSPLNPSIVLSEICADKCRFMDSKMKPLWLLYKNPQAQGDMVGIIFK
NGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYACLSTGNKMGLIEVVKNSDTIANIQR
NSSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNI
MIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREY
CERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKF
NEALRESWKTKVNWMMHSLAKDNRP
>A0A8B9CZT0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anser brachyrhynchus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPYCTSSNLSSMELIAIEFILPTSNKHTKIPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHDSPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8B9I4E0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anser brachyrhynchus|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
NFQDKLYSGNLVVAIHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEIDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRTTTSVWDVCSPFKITLLKGNKLNTEENAKVHVRAGIFHGTELLC
KTIVSTEISGRSDHIWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGEFVLHSWSSFPDELEEMLNPMGTVQTNPYI
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSIQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A667X7R8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MPPAMTDLLDMWAAHSPLAGHATDVITMDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TYPLFPALGEMEGHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQKMTWTEWLQACFSPQLENG
GGAITDGLNDRPADLKVIIHFDQSQDTASLKVSPSCTPTELMELALRKWLTTHGPEDEAR
RGQYVLRVSQRLEFLCGDHGLIQYKYIRSCTQAKESPHLTLVHTSTVKAMFEKEISAIGA
VVTRRSSNPPLPLPPKRRIPTVIQTCVWDVSSQFKIVLVKGSKVNAEESAKVQVRAGLFH
GTELLCKTAVSSESSGRSEHTWSDGTLEFDICVCDLPRMTRLCFAVYAVMDKVKKQKSTK
NTHLNKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPIGT
IQTNPYTENATALHIHFPEYSSHPIVFPLFDKILEKAAEIVKASDCAPVGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRHDCHENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVRCLRDMSKPLIICLSLFLPIPPPPPTSDEELSQY
LLQLVQVLRYEPYYDCALTRFLLDRAQSNRKIGHFLFWHLRSEIHMPAVSVQFALILEAY
CRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYT
ETLSDLHSPLNPSVLLSGINVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQ
DMLTLQILRLMDMLWKEASLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAA
AAAFNKDALLNWLKEKNSGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQ
LFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLI
LRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRES
WTTKVNWMAHNVAKDNRS
>A0A7K5URF4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cephalopterus ornatus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKVKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDTKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSALDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A226NAP4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callipepla squamata|TrEMBL
MPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQLLQDESSYIFVSVTQ
EAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPICEFDMVKDPE
VQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKHIYNKLDKGQIIVVIW
VIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVC
GCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLDTFTMPSYSRRISTAT
PYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQR
VPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINMFDYTDT
LVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSNPVKFPDMTVIEEH
ANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPLSEITEQEKDFLWSHR
HYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRAFA
VRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTNQRIGHFFFWHLKSEM
HNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFL
VEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQ
NNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRYDAAIDLFTRSCAGYCVATFILG
IGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECT
KTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTE
QEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>G5C538|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Heterocephalus glaber|TrEMBL
MPPGVDCPMEFWTKEENQNVVVDFLLPTGIYLNFPVSLNANLRTIKQVLWYRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDIRPFLPVLRVVAREGDRVKKLINSQISLL
IGKGLHEFDSLGDPEVNDFRAKMRQFCEEAAARRQQLGWEDWLQYSFPLQLEPSAGSWGP
STLRLPNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEDYV
LQVNGRLEYLYGSYPLCQFQVQKPHPKPPPVPTKKPSSVSLWSLEQLFCIELIQGSKVNA
DERMKLVVQAGLFHGHEMLCKTVSSSEVSVCSEPVWKQRLEFDISICDLPRMARLCFALY
AVVEKAKKARSTKKKSKKADCPIAWANIMLFDYRDQLKTGERRLYMWPSVPGGAWLRREP
RWGGVVHGNPNTESAAALVIFLPEVAPHPVYYPALEKVMGGMPLACSSQRCPAWPPRAGQ
AGALRAGQFISDPGAGETRGAARTRHGGGGERGPWARRGAGPSWGPHAARPSAAAILERR
GSGELYEHEKDLVWKMRHEVQEHFPDALARLLLVTKWHKHEDVAQMLYLLCSWPELPILS
ALELLDFSFPDCHVGSFAIRSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRAL
ANRKIGHFLFWHLRYSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALNKLKALND
FVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMK
PLWIMYSSKEAGTTGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLP
TGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALERAIEEFTL
SCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYD
FVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQY
LKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A091H5W3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Buceros rhinoceros silvestris|TrEMBL
SRMPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCSASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPTAKGF
GVGSLHTPSKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQSSCIASPPK
AAAKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQGFSGLRLSPVYALSCDSHGQKLQLKEILERRSHTELYEHEKDLVWKMR
YDIRDLYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSF
AINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEM
HVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDLVKVSSQKATKPQTKEMM
HVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEEMGGGGVGI
IFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIAN
IQLNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERF
RGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFR
LKFNEALRESWKTKVNWLAHNVSKDNR
>A0A3Q1GIJ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acanthochromis polyacanthus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAYLKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWIISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVGNRDPL
SEITEQEKDFLWRHRHDCINMPEILPKILLAVKWNSRDEVSQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8C5J3C9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Junco hyemalis|TrEMBL
MPPGIYCPTEFWSKGENQSIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPNKNIFVNIRFQSGGESFMFQISPWEFPITLMSYAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPYYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEHPECALAVQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQ
YPQALAKLLIITKWNRHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLK
KLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPAVS
LRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCMKQ
ETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKNGD
DLRQDMLTLQMIQLMDILWKQEGLDLRDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>L5KYZ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pteropus alecto|TrEMBL
MCFSFIMPPAMADILDIWAVDSQITSDGSILVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKLSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISVHVRAGLFHGTELLCKTIVSSEISGKNDHIWNEPLE
FDINTCDLPRMARLCLAVYAVLDKVKTKKSTKTMNASKYQTIRKSGKVHYPVAWVNTMVF
DFKGQLRSGDIVLHSWSSFPDELEEMLNPMGTVQTNPYTENATALYIKFPENKKQPYYYP
PFDKIIEKAAEIASSDSANVSSRGGKKFLVELKEILDRDPLSQLCENEMDLIWTLRQDCR
ENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVEC
LQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVHIPA
VCIQFGVILEAYCRGSVGHMKVLSKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSK
MKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCL
ATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFT
LSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTY
DFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQ
YLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A1A6GHI4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neotoma lepida|TrEMBL
MELENYEQPVVLREDNLRRRRRMKPRSAVGSLSSMELIPIEFVLPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDHFLLLYQKKGQWYEIYDRYQVVQTLD
CLRYWKMMHKSPGQIHVVQRHAPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIANNCIFIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMNIPESLSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
DEIHLVLDTPPNPALDAVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPALSSKASAEMPGSESKGKSQLLYYVNLLLIDHRFLLRHGDY
VLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSE
IAQSRHYQQRFAVILEAYLRGCGMAMLQDFTQQVQVIEMLQKVTIDIKSLSAEKYDLKHK
LETLQNSGLPKSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTVLSNETIGI
IFKHGDDLRQDMLILQ
>A0A6P5PCC3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus caroli|TrEMBL
MPPGVDCPMEFWTKEESQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLRVCNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYA
LQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHFSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMKLIVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGHITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMR
QETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A1W2P8F6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|TrEMBL
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLD
CLHYWKLMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIANNCIFIVIHRGTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMNISESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
DEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFAEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPSLSSKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRHGDY
VLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSNLP
ESFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGSSGKKTSPHFQKFQDCCVYFTVLW
GCLC
>A0A2K6C9I6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca nemestrina|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3Q3VYB7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mola mola|TrEMBL
MPPAMTDLLDIWAAHSPLAGHALDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPMFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGQAERLLD
SKIGVLIGKGLHELEAINDQEVKEFRSKMFRFSEERMQKVHMMTCTEWLEACFSPHLEPM
PETAITDGTNDRPADLKVIIHFDQSQDSASLKVSSSCTPTELMGLAVRKWLTTHGPEDET
LRGQYVLRVGHCLEFLIGDHPLVQYKYIRTCMQAKEPPHLTLVHNSTIKAMFDKEIAAIG
AVVSPKSSNPPLPLPPKRRVPTVSPLNLYDCVQVRAGLFHGTELLCKTAVSSESSGRSDH
TWKDSTLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNAHINKYQTIRKAGKVHYPI
AWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATALHISFPEY
SSHSIIFPPFDKILEKAAEIAGSSDCASMGRGGKKFHIELKEIMERDALSQLCENEKDLI
WTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLCPRDALELLDFNYPDQY
VREYAVSCLRDMSNEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQASRKIGHFLFWHL
RSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALNKLKAVNELIKFGTIKNARSKT
KEAMLTKEAMMTCLRQSGFSETLSDLHSPLNPNVLLSGINVEKCRYMDSKMKPLWIVYNN
KLLGGDMLGIIFKNGDDLRQDMLTLQILRLMDRLWKEANLDLRIVPYGCLATGDRAGLIE
VVSSADTIANIQLTSSNMAAAAAFNKDALLNWLKERNSGDALERAIEEFTLSCAGYCVAT
YVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGK
TGYPEKFGSFRQYCEKAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGK
TDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A091QT93|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Merops nubicus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEVILLE
IAGNCTVEQMKAQIWMRAIETSQTTEFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFLIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVVAQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGESEENAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C4Z071|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MPPRPSSGELWGMHLMPPRILVDCLLPNGMFLTLECLREATLITVKHELFKEARKHPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDTNGPHSRALYVYPPNVETSTELPKH
IFNKLDKGQIIVVIWVIVTPSNDKQKYTLKINHDYVPEQVIAEAIKKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
TFTMPSYARRISTATPYMNGETATKCLWAINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMASIEEHANWNISRELGYNYCHTSLSNRLARDNPLTDSDNEQLHLVCSRDPL
SEITEQEKDFLWRHRHYCFNIPDILPKLLLAVKWNSRDESAQMYCLLKDWPAIKPEQAME
LLDCNFPDPKIREFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEHMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKEDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERYFVISFNKSDVCFVCL
>A0A8C3QIL1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyanoderma ruficeps|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C3NY65|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyanoderma ruficeps|TrEMBL
MEINSSDNIFCLLNADKISSGMELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIS
IEFILPTNNKHTKAPEILLLEIAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQ
YQKKGQWYEIYDKHQVLQTLDCILYWKVLQKKVGKIYVVQKQKPSEQVQEFQQQLNDLIG
YDVTDVSNVHDDELEFTRRRLVTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNN
IFIIIHRGTTSQKIKVSIDETPDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDE
YITGETPIKDFHWIRQCLKNGEEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQL
TIDGKDHERVFTISLWDCNRKFRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRT
SSKPFTEEVLWNIWLEFDIKIKDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKC
KTQLLYYVNLLLIDHRFLLRSGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAI
SIVLDKYCHPIALPKHRISSDPQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLW
HFRYESIKHPKAYPKLLSSVKWGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFS
DENVRAMAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLF
WFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEK
YDVTSQVIVQLRQKLEKLQGSKLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFK
CADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKI
GMIEIVKDATTIAKIQQSTVGNTGAFKDEILNQWLKEKCLIEEKFQAAVERFVYSCAGYC
VATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMG
TSGKKTSLHFHKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALT
VGKSEEDAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A1A7YKJ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Iconisemion striatum|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLDCLRETPLISIKQQLFVEARKFPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKTRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIVVGRLPHLMLVSKDSLYSQLPAS
GYITPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPMCDNVNTQRVPCSNPRWNEWLTYDLYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYSYCHGLSARLACDSTVSASDAEQLRSLCSKDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMESESAL
ELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKVQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMEN
>A0A8C5CT08|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MPPGNYGMEEEWEAEGNADIMVDFLLPTGIFLEFPVSRNDTILVWRRASSEPLFNALGDP
ASYVFVCISSAAERLELEAEHRRLADVRPFACFLQLVAREGDRAEKLANAQISLLIGKGI
NEFEAQKNHEVSEFRARLRAFCEEKALQQQALPWFQWMECNFPCDLEPCRALPSRGGGAK
APKKIFINIQFEGSDESFMLQQDPQEPPLALIRSALKKKATVFRWVRQEAEDYTLRVNGR
WDFLYGDHPMCQFKYIFSCLRDGQNPQLTMVYHSTIRAYQEDQGSAWRQGSKSSTSASKP
PPLPLKKVGRRGGLCLSLEPLCIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKLVTSSE
VAVGSDPVWNQRLEFDINVADLPRMSRLCIALYAVVEKAKKPRGTKKKSKRADCPIAWVN
TMVFDYKDQLKTGEFLLSMWPSIPDDKSELLNPMGTVEKNTNVDSAAALLIHFPSVRPQP
LYYPPHDKVTGGGGSRAPHRSSDEPNQKLKEIMDNKNHTEFFEDEKELLWKLRGAVQSLY
PESLSKLLVITKWNKREDVAQMVGLLRAWPELSGLHALELLDYSFPDPSVRAFTVKCLKK
LGDRELMQYLIQLVQVLKYESYLDCDLTSFLLERALSNKRIGHFLFWHLRSEMHVSSVSL
RFGLILEAYCRGNIHHIRSLTKQNEALGKLKALSDIVKSGSQKMSADDLKLCIKQDSYME
ALSDLLSPLNPSIILSEICVEKCKYMDSKMKPLWLMYKNQWVPGDLMGIIFKNGDDLRQD
MLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRDNSNSAAT
AAFNKDALLNWLKSKNPEHKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQL
FHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRDYCERAYKIL
CRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKTEEEALKSFKVKFNEALRESW
KTKVNWMMHSLAKDKRP
>A0A8C1LRU3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLETESVE
NLIDKHEGVIKITMHYDQSQVCSVILALKKWQTTHGPEEDIGTRSDYVLRVSCRLEFLLE
DHPLNQCKYIRDCLLANESPHLTLVHCDVVKAIFEKEICTIGSVLARKASNPPLPLPPKK
RTPTVRTLSVFPALQLIKGALSFVPLAVRAGLFHGTELLCKTAVSSESSSRSEHVWNKTL
EFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHYPIAWVNTMV
FDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVF
PAFDKILEKAAEIAGASDSMTIGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRYDC
RENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVN
SVRDDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMYMPAV
SVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKLGTIKTKTKQAHLKEAMMTC
LRQTGFIETLSNLHSPLNPNILLAGVHVERCKYMDSKMKPLWIVYHNKLLGGDTVGIIFK
NGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQK
TSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGNFFRQ
YCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQK
FDEALRESWTTKVNWMAHIVAHPS
>A0A8C1J8V5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGLCHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVA
QSGKSRSVKKILVNVKFEGSEVSEFMLIYHSFMLSGNSFLWYNAIKKSTVFRAAKQEKPE
DYTLQVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQMS
RTRAPSKPPPLPLKRVRMHFYTGTRSVINRGTTCHLSLVLVVQAGLFHGSELLCKVVISN
EVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRDCPLAWVNT
MVFDYKDQLKTGEFSLSTWPSVPDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPP
IEKVHFCVIAFCCFQLNELGMNGEKVHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQR
YPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHVRSFTIRCLR
NLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRSEMHVPSVS
LRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQ
DTYMEALSDVVSPLNPSIVLCELCTDKCKFMDSKMKPLWLMYKNKYDHVGIIFKNGDDLR
QDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSA
ATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETG
QLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYK
ILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRE
SWKTKVNWMMHTFAKDNR
>A0A8C2B049|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MVNAGNKLIAVTFVVRREENKRRRRKMKAFTSTSAVSTDHIAVEFVLPTTNKNSKYPDTL
HLDVTGNWTVEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQ
TLDCIRYWKALRKEVGKIHLVIRQQPNEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITPKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSI
DDTPVQVLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAISDFHWIRQCL
KNGEEIHLVLEHPPDPELDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDC
NRKFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFN
IKIKDLPKGARLSLQVSCGKAQTQTSKENECKNKTRLLYYVNLLMVDHRSLLRQGEFILH
MWKMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGE
RGQREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQ
EAVAITHCLLERSTVWDRSSHDVGLALQLLDCHFSDENVRTLAVRKLETLEDDDVLRYLL
QLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYL
RGCGEAMLQDLRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPD
SFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSRDTIGIIFKDGDDLRQD
MLILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGA
FKDEILSQWLSEKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLF
HIDFGHILGNYKSFMGISKERVPFVLTPDFLYVMCTTGKKSSPYFLQFQNVCLKAYLALR
HHTNLLIILFSMMLMTGMPQLSSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWT
VQFNWFLHLVLGIKQGVEKRSA
>A0A8C2HRL3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWVESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQNIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKRISEEKMQCMQLMSWGEWLRSCYSMTLEAGSLE
NLIDKHEGVIKITMHYDQSQDTSSLKVSLHCTVTELMDLALKKWQTTHVPEEDIGFRSDY
VLRVSRKLEFLFEDHHLNQCKYIRDCLLTNESPHLTLVHCDVVKAMFEKEISTIGSVLAW
KTSNPPLPLPPKKRLPTQLHTCVWKVHSLFRIHLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSP
RDALELLDFNYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLER
AQSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVN
ELIKFGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGVNVERCKYMDS
KMKPLWIVYNNKLLGGDTVDIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGC
LATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
HDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A8C1NIJ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
NCLIDRISCHTIKQTKYTLNEPLFSALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLF
LPILRLVAREGDRVEKLITTQISLLIGKGLCHHEFESQKNHEVNEFRTKMRTFCEERAQV
RQMLPWDKWMEYNFPCDLEPCSVVAQSRKLCSGKKIFVNVKFEGSEVSKVHINIQFFYAT
IQLNALRKKSTVFRSAKQEKPEDYSLQINGRWEFIYGKYPLCQFKVSLKITTSSRLHSYI
FFKIHMKASHFQTPGCMSFYILSYRFQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQ
AGLFHGSELLCKVVISNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKR
PTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFSMSTWPSVPDLLNPMGTVEKNPNIDSTA
GLLIRFPNIRPHPLYYPPIEKLNDLGMNGEKTTKEEVRNNMHRSFFEDEKELLWKLREEV
RQRYPESLPKLLLITKWNKHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIR
CLRKLSDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVP
SVSLRFGLILEAYCRGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVC
IKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGD
DLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNS
NSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIS
ETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQ
AYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEA
LRESWKTKVNWMMHTFAKDNR
>A0A8C2AM12|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
LNSSDDEPPVVRREENKRRRRKMKAFTSTSAVSTDNIAVDFVLPTTNKNSRNPDTLHIDV
TGNWTVEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTLDC
IRYWKALRKEVGKIHLVVRTQPNEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRKLL
TPRKIELADRDPKLYSMDPWITPKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDDTP
VQVLQSFFAKIKKKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKNGE
EIHLVLEHPPDPELDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRKF
RVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFHIKIK
DLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLLVDHRSLLRQGEFILHMWKM
PEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERGQR
EMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEAVM
ITHHLLERCTVWDRSSLDVGLAIQLLDCHFSDEKVRTMAVRKLETLEDDDVLRYLLQLVQ
AVKFEPYHDSALARFLLKRALRSQRIGHFLFWFLRSEIAQSMHYQQRYAGVVEAYLRGCG
EAMLQDFRKQVEMTEALQKVTREIKLMSAEKYDVSQQVVLQLRQKLEGLQTSGLPDSFKV
PYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDMLIL
QILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDE
ILSQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDF
GHILGNYKSFMGISKERVPFVLTPDFLYVMSTTGKKSSPHFLQFQNVCLKAYLALRHHTN
LLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLEQIEICRDKGWTVQFN
WFLHLVLGIKQGVEKRSA
>A0A8C2A990|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVAQS
GKSRSVKKILVNVKFEGSEETFVLQQDPQDLPMLLKRNALRKKSTVFRAAKQEKPEDYTL
QVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQMSRTRA
PSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGMNGEKVVTTKEEHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQ
RYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHVRSFTIRCL
RNLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRSEMHVPSV
SLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIK
QDTYMEALSDVVSPLNPSIVLCELCTDKCKFMDSKMKPLWLMYKNKYDHVGIIFKNGDDL
RQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNS
AATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRET
GQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAY
KILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKVNWMMHTFAKDNR
>A0A094L8V2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podiceps cristatus|TrEMBL
NSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMEWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISSPFKIILLKGNKLNTEENAKVHIRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SRYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALNIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K8S3N2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhodinocichla rosea|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGAIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPATKGLSS
LQIPTKNIFVNIRFQSGGESFMFQISPWEFPITLMSYAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7K9ZYU5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicrurus megarhynchus|TrEMBL
MELGDHEQPVVMREENKRRRRKMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEVVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRPRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLEGLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A668UD05|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRSKMFRISEERMQQIQMMTFSEWVQACYSPQLEPA
AVTAITAGVNDAPVDLKVIIHFDQSQDSASLKVSLSCTPNELMEQALRKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKETPHLTLVHTSAVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRRAPTTCVWDVPKPFRIVLVKGSKVNAEETAKVQVRAGLFHGT
ELLCKPAVSNESSGRSEHTWKDNTLEFEISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNP
HINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQ
TNPYTENATALHIHFPEYSSHPIVFPPFDKIKCTFSSYRPSTENPLMGGRGVKKFYMELK
EIMERDPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIWP
KLSPRDALELLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTHF
LLERAQRNRQIGHFLFWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQVEALSKL
KSVNELIKLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDINV
EKCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLD
LRIVPYGCLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDA
LDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKR
ERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLP
ELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8D0CNI3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MPPGKYGMQEEGDQEIMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNARSEALFSALGD
PDAYVFTCINQTAEREELEEESRRISDVRPFMGVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFEAQKNHEVNEFRAKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPECGSVK
SKNTKKIFINVKFEACDESFMLQQDPQDFPVALMKSALKKKATVFRSVRQEPEDYTLQVN
GRWEFIYGNHPMCQFKVSDRSRLKPQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQA
GLFHGSELLCKVVTTSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPR
GTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNV
DSAAGLLIRFPNIRPHPLYYPPLDKVRILKSDMEKNGDAAIVTKEERMKLKEIMDNKNHT
EFFEDEKDLLWKLRTEVRDHYHESLSKLLLITKWNRREDVWKCFLLRTWRDLPAIHALEL
LDYSFPDPVVRSFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWR
IGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDFVKSG
SQKMTADDLKLCIRQESYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPIWLMYNPC
TQEDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVV
KNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDRAIEEFTLSCAGYCVATYV
LGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTN
NSEKFERFREYCERAYKILCRNGMLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSE
EEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A8D0AIM5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MVVPREATIQHIKLLLWKQAQSHPLFSSLGEMESHMFECVNQAAVHEELEDETRRLCDVR
PFLPVLKLVTRSCGRAERLLDSKIGVLIGKGLHELDAINDQEVKDFRSKMFRLSEERMQQ
VQMMTCTEWLQACFSPQLEPLAGTAITDGLKVPSSCIPSDLMELAVKKWLTTHAPEEEVW
LGQYILRVSHCLEFLCGEQPLIQYKYIRTCMQAKESPHLTLVHTSTVKGMFDKEISAIRA
VVSRKSSNPPLPLPPKRRVPTYVWDVSSPFKIVLVNGSKVNAEETAKVQVRAGLFHGTEL
LCKPAVSSESSGRSDHTWKDSTLEFDLSVCDLPRMTRLCFAIYAVMDKVKKQKSTKNHYP
IAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATALHIHFPD
VPCMSLQHVTLKSQFPAFLDLGRSMLHLKEIMERDPLSQLCENEKDLIWTLRYDCRENFP
QSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLRDM
SDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQ
FALMLEAYCRGNIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMT
CLRQSGYSETLSDLHSPLNPNVLLSGINVERCRYMDSKMKPLWIVYNNKLLGGDTLGIIF
KNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQ
LTSSNVAAAAAFNKDALLNWLKERNTGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQ
YCEEAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEDALKQFRQK
FDEALRESWTTKVNWMAHNVAKDNRS
>A0A3S2PAA0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias javanicus|TrEMBL
MPPRPSSGELWGMHLMPPSIVVDCLLPNGMILSLECLREATLVTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILSREIGFA
IGMPICEFELVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSADLPRH
IYNKLDKGQIIVVIWVIISPSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPSD
NFTMPSYARRISTATSYMNGETSSKNLWTINGMLKIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLSYDMYILEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEQF
SSPVKFPDMAYVEEHANWNISRELGFNYSHTGLSNRLARDNPLTDNDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHSCINIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKEDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>C3XYJ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Branchiostoma floridae|TrEMBL
MPPVEAFMLDIWAKEADSPTIQVDCLLPTGIYIPLTCSRDATIEQIKRDLWQEARTYPLY
SELAEVQSYVFMCINQTAEQEELHEEQRRLCDVRPFRPILKLVQKKKDPAAVEKLLNSQI
SVLIGKGLHEFDSMKDPEVDEFRGRMRQMVRDIADSRKEKSWVERLQYQFPPRLESSEDL
PKHMQPANNNLVVNIRFHNTDMSYSFQVHVMAFPIELHQLALKKKASFLRQPEEDPADFT
LKVCGQFDYLIGEFPISRFKYVRKCLSKATTPQLMLVNLDNIDLEPVTSPTTPDPEGPPP
LPCKQEKMVSLWNIEARVKITVVFVKAGLYHGGETLCSISTTKEASCVGGDASWSEVLEF
DLDVNDLPRMARICLAIYEAGKKGRKSKKGRESRESYPKDSIPLGWVNITMFDYRDHLRS
GTFVLHTWPWPDSGAEVLNPIGTVVSNPNFGATALQVELHSYHACPIIYPPFDKNQLQCI
LDRELMAPMFDQDMEMIWQLREKIHELFPHALAKLLSSVKWNNHRDVAQMQALLNAWSPL
LPHAAMELLDYNYADQAVRAFAVKCLNQLTDEELSQYLLQLVQVLKYEAYLDCELARFLL
MRGLNNQRIGHYLFWHFRSEMHNPAVSVRFGLLLEAYCRGCSTHMKALSRQMEALSKLKT
VNELVKKQAIKNEKHKQLSLEAMKACLKQTSYHDALSHIHNPVEPQFKLLQLSNDHCKFR
DSKMRPLWLVFENEDRFGDHVTLMFKDGDDLRQDMLTLQIIQVMEMLWQAEGIDLRMSPY
GCLSTGNKVGLVEVVLNADTIANIQKDKGSTATAGFKKGSLFMWLKEKNPEKESLNKAVQ
EFTLSCAGYCVATYVLGVGDRHSDNIMIKETGQLFHIDFGHFLGNFKTKFGIKRERVPFV
LTHDFVHVITKGQSTQGSQEFAAFRQHCEGAYLSLRKYGNLLISLFAMMLSSGLPELTSP
SDINYLKDKLALEMTQEEALRHFREEFDNALKQSWKTSVNWWLHNIAKDNK
>A0A7K7M4E0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Brachypodius atriceps|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPETMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKANLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDESVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A4W3H5L2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPGMQYHQDLWSEDENPDVEVEFLLPTGIYLNFYVPRSSTISYIKKLLWQQAQQQPLFH
TLNEPDAYVFTCINHTAEREELEDERRRLCDVRPFLPVLKLVAREGDRAEKLINSQISLL
IGKGLHEFDCMQDYEVAEFRLKMRQFCEDKESERLRMSWQDWMEYSFPRELEPIQEAPDN
NMIRTLSNRNIVINVKFQYNEESFSFQISPQSHPGTLMQMAVKKKATVFRHKTVEHTEDY
TLQVNGTEEYIYGNYPLGQFKHIWNCMYSSSTPHLTMVHSSTINSLKGEQSNSIAQVPKS
RTYSKPPPLPIKKVPPPRPFSLSLYLFLSPFIRPTLRCGGGGELVVQAGLFHGSEMLCKT
VSSHEVSVCSEPAWDQALEFDIHFSDLPRMTRLCFALYGVIDKAKKARSTKKKSKKADCP
IAWVNTMVFDYKDQLKTGDVWLHMWPSIPDEKGELLNPMGTVQGNPNTDSAAALYVRFRG
VLFFLPQILELGKNGDHSKASPTEQQQLKEIMERKSCTEFFEDEKDLVWKLRWESRDHYS
DALAKLLSITKWNKHEDVAQMIYLLQSWPELPALHALELLDYSYPERYVRSFAINCLKNL
RYEELFQYLLQLVQVLKYEPYLDSELTKFLLNRALANKKIGHFLFWHLRSEMHVPAVSLR
FGLILEAYCRGNNYHMKSLMKQCESLKKMKALNDFVKSSSQKTTKPKTKEALHLFMRQEA
YMEALSNLHSSLNPSSLLTDLWVDKCKFMDSKMKPLWIVYKNEKYDGDPMGVMFKNGDDL
RQDMLTIQMIQLMDVLWKRQGLDYRMIPYACLSTGDKTGLIEVVSRSETIANIQLNKSNM
AATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIREN
GQLFHIDFGHFLGNFKSKFGINRERVPFILTHDFVHVIQQGKTSNSEKFERFRKYCEHAY
MILRKHCPLFINLFALMRAAGLPELSSSKDIQYLKDSLALGKTEEEALKHFKMKFDEALR
ESWKTKVNWMAHNVAKDNRS
>A0A7K8YDV6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sakesphorus luctuosus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCASSSFSSMELISIEFILPTSNKHTKVPEIILLE
IAGNCTVEQMKAQIWMRAIEMSQTSDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSQEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDSPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKEKCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K8QIC0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Smithornis capensis|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLDTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGP
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K8QI16|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Smithornis capensis|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSAKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTTLSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8D2L4A8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Varanus komodoensis|TrEMBL
MMPPAMADALDIWAGDSQIAADGSISLDCLLPTGIYISLDVPRDATICYIKQLLWKQAHS
YPLFHLLLESDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVFQLITRSCDPGEKFDSK
IGVLIGKGLHEFDALQDPEVKEFRIKMRRISEEKMQSLVGLSWMDWLKYTYPAELEPSIQ
DNLQDKLYGGNLVVAIHFDSCQDVFSFQVSPNINPIKLNEMAIRKRLTIHGKEDEEVDPY
EYVLQVSGRLEYIFGDHPLIQFQYIHHCVLNRALPQLTLVECSTIKKMCDQEMVATEAAI
NRKQLNPPLPLPPKKLRAIQSVWDISHPFKVILVNGNKLNTEETAKVHVRAGLFHGTELL
CKPIVSSEISGRNDHVWNEPLEFDISVCDLPRMARLCFVVYAVMKNKKSGRPLNPPKYQT
IRKAGKVHYPVAWVNTMVFDFKGQLKTGDFTLHSWSSFPDELEEMLNPMGTVQTNPYTEN
ATALQIRFQEYSKMPIYYPPFDKGRGGKKFHIELKEIMERDPLSQLCENEMDLIWTLRYD
CRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWSKLPPREALELLDFNYPDQYVREYAV
GCLRQMSDEELAQYLLQLVQVLKYEPFLDCALSRFLLEKALANRRIGQMLFWHLRSEVHI
PAISVQFGVILEAYCRGSIAHMKVLYRQVEALNKMKTLNNLIKLNAVKQSRAKGKDTMHT
CLKQRAYKEALSNIQSPLNPSVLLSELHVEKCKYMDSKMKPLWIVYNNKVFGGSLVGIIF
KNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRILPYGCLATGDHSGLIEVVSSSETIADIQ
LNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEAFTLSCAGYCVATYVLGIGDRHSDN
IMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQ
CCEEAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQK
FDEALRESWTTKVNWMAHTVRKDYRS
>A0A6P8G389|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Clupea harengus|TrEMBL
MPPAMTDVLDLWAELGQVEAELVSVDFLLPTGLYIQMDVPREATIQHIKLLLWKQAALYP
LFSALGQMEGCVFECVSAAAVHEELDDESRRLCDVRPFLPVLRLLRRGCADNQRVLSSKI
GTLIGKGLQELDSLQDQEVKDFRLKMQRISEEKLLRLQMMSYGEWLQASFSPQLEAGPTD
DVIDKLTEGGVKITIHYDQSQDTASVRVCVSSNVEQLVDHALKKWSSTHQQQGCHDDYIL
RVSGKLEFLYGKHPLIQYKYIRSCVLAQEAPHLTLVHVDVIKSMFQKELNVVSAALSQRP
ANPPLPQKKRATSQVQVCVWDVQCPFKVILVRGIKVNAEETAKVQVRAGLFHGAELLCVP
SVSEEVSGRAEHVWRHTLEFDISVCDLPRMSRLCFALYAVSHKKKQKSTKHSHKYQTIRK
AGKVHYPIAWVNTMVFDYKGHLKTGDILLHCWSSFPDELEEMLNPIGTVQTNPYTENATT
LHIQIPDYSSQPIIFPPFDKILEKAAEVAKGSDCPPMTGRGGKKFHIELKEIMDREPLAQ
LCENEKDLIWTLRYDCRENFHQSLPKLLLSVKWNKHEDMAQLQALLQIWPKLSPRDALEL
LDFNYPDQYVREYAVNCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLERAQNNRF
IGHFLFWHLRSEIHMPAVTVQFALLLEAYCRGSIPHIEVLKKQVDALSKLKAVNSLVKTG
AVKSKARSKDGHLKEAMLTCLRQSGFTEALADIHNPLNPSVLLATVNVDKCKYMDSKMKP
LWIVYDNKLLGGDTLGIIYKNGDDLRQDMLTLQILKLMDKLWKEANLDLRILPYGCLATG
DRSGLIEVVLLADTIANIQKTSSNMTATAAFNKDALLNWLKEKNSGDALERAIEEFTLSC
AGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFI
HVIQQGKTANTQKFGSFRQYCEEAYLVLRRNGNLIITLFALMLTAGLPELTSVKDIQYLK
DSLALGKTDDDALKQFRQKFDEALRESWTTKVNWMAHHLAHAS
>A0A7L4L4A2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callaeas wilsoni|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFITIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSV
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C6SY65|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neogobius melanostomus|TrEMBL
DIQVPDGMSLSGASLVPHASGCLREATLITIKHELFKEARKYPLHQLLQEETSYIFVSVT
QEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVIEFELVKDS
EVQDFRRNILNVCKDSVELRDSSGPHSRALYVYPPNVESSQELPKHIYSKLDKGQIIVVI
WVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQGKYILKV
CGCDEYLLEKYPISQYKYIRSCIMLGRMPNMMLMAKDSLYTQLPTDTFVMPSYSRRISTA
TSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQMCDNVNTQ
RVPCSNPRWNEWLTYDMYIPDVPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTH
TLVANKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHFSSPVKYPDMNAVED
HANWTISRELGFNCNFSGQSNRVARDHALTESDSEQLRQLSNRDPLSEITEQEKDFLWRH
RHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAMELLDCNYPDPMVRHF
AVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSE
MHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMRF
LVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMSEMLF
QNNEIIFKTEMDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRSSHTIM
QIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRSCAGYCVATFILGIGDRHN
SNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLMVISKGSQECTKTKEFE
RFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKTEQEALDY
FMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A7K4W5B2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tachuris rubrigastra|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GCLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEPPRGAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C5WVN7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Laticauda laticaudata|TrEMBL
MPPRPSSGELWGMHLMPPKILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVELRDANAPHSRALYVCPPNIESSDLPKHI
YNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLKL
CVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMTKESLYAQLPLDT
FAMPSYSRRISTATPYMNGEASAKSLWAINSHLRIKILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLQYEMLVHDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFS
SPVKFPDMSVIEEHANWIISREQGFNYNHAGLSNRIARDNELRDNDKEQLRAICTRDPLS
EITEQEKDFLWSHRHYCVSMPEILPKLLLSVKWNSRDEVAQMYCLIKDWPQIRPEQAMEL
LDCNYPDPMVRAFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQ
RIGHFFFWHLKSEMHNKNVSQRFGLLLDSYCRACGMYLKHLSRQVEAMEKLINLTDILKQ
EKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLWL
NWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSI
GDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDPAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGAQECTKTREFERWVSWNRNAIWSDQISVAGRC
>A0A1U7SS21|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carlito syrichta|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAVRRQQLGWEAWLQYSFPLQLEPSARSWGA
GGLRLPSRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPPVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYIRSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPVKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISVCDLPRMARLCFALYAMIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
HPVYYPALEKILELGRHSGCGHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLGALELLDFSFPDCHVGSFAIKSL
RKLKDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMRVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7L3N6W8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreotrochilus melanogaster|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPETMLLE
IAGNCSVEQMKAQIWLRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKIKVSIDDS
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHDRVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEVNIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHDSPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLTKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVHVIELLHKVTMEIKSASAEKYDVTSQVITQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8D2NPR7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zosterops lateralis melanops|TrEMBL
MPPGIYCPTDFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWQQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPLTLMSYAIKKQATVFRHETVQKAEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKVP
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVAVCSEPVWRQRLDFDIGICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAPPPSTFHPSGPVCALCWEQKLQLKEILERRSHTELYE
HEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDF
SFPDRYVGSFAINSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGH
FLFWHLRSEMHVPAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQK
ATKPQTKEMMHMCMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNN
EETGRGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIE
VVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVAT
YVLGIGDRHSDNIMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGK
TNNNEKFERFRGYCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGK
TDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A1W7RET4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Agkistrodon contortrix contortrix|TrEMBL
MELESSDQAVVMRDDNKRRRRRRMKPYCTANTFSSTELISIEFVFPTTSIVLDVATNCTV
EQMKAQVWMQAVEGHQTSELFRKITPDQFLLLYQKKGQWYEIYDKHQIMQTLDCILYWKV
LQKKVGKIHVIEKPSPSEEVQEFQRQLNYLIGYDVTDVSNVHDDELEFARRRLVTPRTIE
VSCRDPKLYSMHPWTTSKPLPEYLLSRIVNNNIFINIHRGTTSQKIKVGVDDTPEVILQS
FFTKMAKKKSLMNIPEDYSELDFVLRVSGRDEYIVGETPIKNFHWIRQYLKKGEEIHLVL
DEPPDPNQDEVQKEEWPLVDDCTGVSGYHEQLTIQGKDHERVFTISLWDCNRKFRVKVIG
IDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTTAKPFNEEVLWNVWLEFDIKIKDLPKGA
LLTLQIYCGKTPAPSTKGNLHSYDSPNSDPKYKTQLLYYVNLLLIDHRSLLRTGDYVLHM
WKIPGKGEEQGSINADKLTSATNPDKENSMAVSIVLDKYCHPIALPKHKIASDPQGDRAR
AEMPNQLRKQLEEIIATDLLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQELV
AETYQLLAKRDAWDQSALDVGLPMQLLDCNFSDETVRTMAVQKLEGLEDDEVLHYLLQLV
QAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGC
GKAMLKDFLKQVQVTELLHKVTRDIKAASAEKYDVTPQVIAQLKQKLERLQENKFPECFR
VPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTSLSSETIGIIFKHGDDLRQDMLI
LQILRIMASIWEEDSLDLCLLPYGCISTGNKIGIIEIVKDANTIAKIQQSTVGNTGAFKD
EILNQWLKEKCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITGSGNLFHID
FGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLRFQNFQDICVRAYLALRKHS
NLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKHEDDAKKYFLDQIEVCRDKGWTVQF
NWFLHLVLGIKQGVEKHSA
>A0A093L1B2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eurypyga helias|TrEMBL
SRMPPGLYCPMEFWSKEENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPL
FHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGL
GTGPLHTSTKNIFVNVKFQSGGESFTFQISPEEFPVTLMNYAIKKQATVFRHETLENPED
YTLQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTILAMRDEQTNCIASPPK
MAAKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQVGDTDTFLGRPRNCSFAGAGASSVTKLQLKEILERRNHTELYEHEKDL
VWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDR
YVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWH
LRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKSLNELVKVSSQKATKPQ
TKEMMHVCMKQETFLEALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFSNEETGG
AGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHS
DTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGLSCAGYCVATYVLGIGDRHSDNIMIR
ETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEK
AYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEA
LRDSWKIKVNWLAHNVSKDNR
>A0A8C9FRV8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pavo cristatus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELITIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAIEVSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDLFPLVLSLLDCRALHMLLTRLLCIFQAVKFEPYH
DSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLHDFM
KQVQVIELLHKVTMEIKSVSAEKYDVTSQGLSAFKLKELNTSQLRNTEVLSIEKCKVMAS
KKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWEAESLDLCLLP
YGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEILNQWLKDRCVIEEKFQAAVE
RFVYSCAGYCVATFVLGIGDRHNDNIMITETGESGSRCLFDGVTASVDEGRAIDVVYLDL
CKAFAMVLHHTLVSKL
>A0A2P4THR7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bambusicola thoracicus|TrEMBL
MPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQLLQDESSYIFVSVTQ
EAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPICEFDMVKDPE
VQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKHIYNKLDKGQIIVVIW
VIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVC
GCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLDTFTMPSYSRRISTAT
PYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQR
VPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINMFDYTDT
LVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSNPVKFPDMTVIEEH
ANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPLSEITEQEKDFLWSHR
HYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRAFA
VRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTNQRIGHFFFWHLKSEM
HNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFL
VEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQ
NNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRYDAAIDLFTRSCAGYCVATFILG
IGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECT
KTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTE
QEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C5TMS9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Malurus cyaneus samueli|TrEMBL
LCFNSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLW
KQAHSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGE
KLDSKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQ
EPVIPESIQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDE
EVDPADYVLQVSGRLEYVFGDHPLIQFQYIRTCVMNRTLPQLTLVECCTIKKMCEQEMIA
IEAAINRKSSNLPLPLPPKKTRSVWDICNPFKIVLLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNT
SKYQTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLRQMSYSNCFYVPHSSDEELSQYLLQLVQVLKYEP
FLDCALSRFLLERALGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLA
KQVEALNKMKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSE
LHVEKCRYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEA
GLDLRILPYGCLATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNL
GEDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFG
IKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTA
GLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6I8PK17|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ornithorhynchus anatinus|TrEMBL
MDPEAPEPPVLLREAAKRRRRRMKAYGTPGPPVPPAPSELIPIEFTLPARRRDSPETPET
VTLDVPGNGSVEQMKAQLWAHAAELGPVGAFFQRSCPDQFLLLYQKRGQWYEVYDRHQAV
QTLDCVLHWKVTRLPVGHIRVAPRPQPTPEVLDFQRRLTELIGYDVTDVSNVHDDELEST
RRRLLAPRAAEVAGRDPGLYAMHPWVTSKPLPAYLQGKVANGHVLLVIHRGTTSQTVKVS
VDETPGAILRGFFTRMAKKKSLMGIPEGLGERDFVLRVCGRDEYLVGETPVKNFQWVRQC
LKNGEDIHLVLDAPPDPALDRVREEEWPLVDDGPGATGYHDQLTVAGKSHERVLTVSLWD
CDRRFRVKIRGFDGPAAPPRGPEPTVFVEAKVQHGQQLLSQSRTTSKPWAEEVLWNQWLE
FGIRIKDLPRGALLNLQIYCGRAQGGPPPAPGSPGPGSDPRARHQLLYYVNLLLVDHRSL
LRRGGYVLHMWKTSGKEDGRGSLNADKLTSATNPDKENSVAISVLLDDYCHPVALPKHRP
ASGPDGAGAGAGGRAEMPNQLRKQLEEIVATDPLHPLSAEDKELLWHFRHESLKHPEAYP
KLFSAVDWGRQETVAVAYRLLARREVWDRSALDVGLTLQLLDCNFSDENVRAMAVQKLES
LEDDDVLHFLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSPHYQ
QRFAVLLEAYLRGCGQAMLQDFTRQVQVTRLLHKLTLEIKSLSADKYDVTPQVVAQLKEK
LENLQNSHLPDSFRVPYDPGLKAGKLVIEKCKVMASKKKPLWLEFQCADPTALSSETIGV
IFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAK
IQQSTVGNTGAFKDEVLHHWLREKCPIEEKLQAAVARFVYSCAGYCVATFVLGIGDRHND
NIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLFVMGTAGKKTSKHFQKFQ
EVCVRAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIAYIRDALTVGKSEEEAEKYFLD
QIEVCRDKGWTVQCNWFLHLVLGIKQGEKHST
>A0A7K8GIX8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Orthonyx spaldingii|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVPKGLGT
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAVKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDHKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAAEHSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEDTGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKLPFNPFLALSRDALDQAIEEFTLSCAGYCVATYVLGIG
DRHSDNIMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEK
FERFRGYCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEAL
KHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K8GMG1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Orthonyx spaldingii|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTPSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQSTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQMYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A4W4HIG7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MPPGVCYGMQDVWEKGGREQVTLEFLLPTGIYLSFPVARNDTIGTIKKMVWKNARSEPLF
SVLSDPDAYVFTCINLTAEREELEDESRRLCDVRPFMPVLRLVAREGDRVEKLINTQISL
LIGKGLHEFDTQKNHEVNEFRAKMRSFCEENAQDRQRLPWHQWMKCNFPCDLEPFSMVVQ
SGKSCSVKKLLVNVKFEASEESFMLQLDPQDFPVVLMQNALRKKATVFRPLKQEKPENYT
LQVNGRWQFIYGNSPLCQFKYIFSCLYGGIKPHLTMVHHSTIIKYQEEQGGLSNQVSKSR
SLSKPPPLPLKKQNTSSLWSIKEPFFIQLVHGTRVNTDEGMKLVVQAGLFHGGELLCKVV
TSSEVSVCSDPVWDQKLVFDINLCDLPRMSRLCFTLYGVLEKTKKQRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSAPDDKGDLLNPMGTVERNPNIDSTAGLLIRFPSF
RPHPLYYPPLEKVNRTSVRIHKTEGIGQHLKLKEIVDNKNHTEFFEHEKELLWKLRLDVR
AHYPESLSKLLLITKWNKHEDVAQMVCLLRTWRDLPPLHALELLDYTFPDPHVRSFTIRC
LKKLGDEELFQYLLQLVQVLKYESYLDCDLTTFLLERALSNKKIGHFLFWHLRSEMHVAS
VSLRFGLILEAYCRGSIYHIKSLMKQIEALNKMKALNDFVKSGSQKSASRLQITEDMKLC
IKQDTYMEALSDVISPLSPSIVLSEICPDRCKFMDSKMKPLWLMYKNKWDHLDTVGIIFK
NGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMVPYGCLSTGNKTGLIEVVKNADTIANIQR
NSSNNAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRENGQLFHIDFGHFLGNFKAKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREC
CEQAYKILCRNGTLFVNLFALMRAAGLPELSCSKDIQYLKDSLALGRSEEEALKNFKVKF
NEALRESWKTKVNWMMHTVAKDNR
>A0A8C6H7D4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus spicilegus|TrEMBL
MPPAMADNLDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRRKMRKFSEAKIQSLVGLSWIDWLKHTYPPEHEPSVLE
NLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEDEASPCDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINR
NSSNLPLPLPPKKTRVISHIWDNNNPFQITLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQ
TIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQTNPYAE
NATALHIKFPENKKQPCYYPPFDKIIEKAAELASGDSANVSSRGGKKFLAVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALD
NRRIGQFLFWHLRSEVHTPAVSIQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLI
KLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPL
WLVYSSRAFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGD
RSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCA
GYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6J1ZGV1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acinonyx jubatus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLLERPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPLWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSAPDEKGELLNPAGTVRSNPNTESAAALVICLPEVSP
YPVYYPALDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPDLPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMRQGEALSKLKALNDFVKVSSQKTTRPQTKELMHLCMR
QETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDSSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGPLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C2ECC9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVI
SNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKTLILTDGTVFFQHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQRYPES
LPKLLLITKWNKHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLSD
DELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSLRFG
LILEAYCRGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYM
EALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQDML
TLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAA
FNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMISETGQLFH
IDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCR
NGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKT
KVNWMMHTFAKDNR
>A0A8C1X4A7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLETESVE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDY
VLRVSCRLEFLLEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAIFEKEICTIGSVLAR
KASNPPLPLPPKKRTPTVRTLSVFPALQLIKGALSFVPLAIQVRAGLFHGTELLCKTAVS
SESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRK
AGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATE
LHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTIGRGGKKFYIELKEIMERDPLSQL
CENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELL
DFNYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKI
GHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKLGT
IKTKTKQAHLKEAMMTCLRQTGFIETLSNLHSPLNPNILLAGVHVERCKYMDSKMKPLWI
VYHNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHS
GLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGY
CVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVI
QQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSL
ALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A673JN71|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGSHSRALYVYPPNVESSSELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKYPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTEADIEQLRQLGNRDPL
SEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A4W2DQB3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos indicus x Bos taurus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>K7BKN5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan troglodytes|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A2Y9NZC3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Delphinapterus leucas|TrEMBL
MPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKQTYPPEHEPSIPE
NLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDEVSPYDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAIEAAINR
NSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TVVSSEISGKNDHIWNEPLEFDISTCDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQ
TIRKSGKVDYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALA
NRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLKTLNSLI
KLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYIEKCKYMDSKMKPL
WLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGD
HSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCA
GYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>U3E7X7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callithrix jacchus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGTIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDGLKDPEVNEFRRKMRKFSEETILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
ISPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIILVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEVSGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKAKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6J3DHK5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aythya fuligula|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
NFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEDIDPAD
YVLQVSGMLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDVCSPFKITLLKGNKLNTEENAKVHVRAGIFHGTELLC
KTVVSTEISGRSDHIWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGEFVLHSWSSFPDELEEMLNPMGTVQTNPYI
ENATALHIKFQEYSKHPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFFVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSIQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3Q0G067|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alligator sinensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWSLNSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMFILELPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMTVIEEHANWAIARELGCNYSHAGLSNRLARDIEVRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHNCVNTPEILPKLLLSVKWNSRDEVTQMYCLIKDWPPIKPEQAME
LLDCNYPDPMVRSFAVQCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQRANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A6J2H9S2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pipra filicauda|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P9D1H5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pantherophis guttatus|TrEMBL
MELESSDQAVVMRDDNKRRRRRRMKPYCTANTLSSTELISIEFVFPATSIVLDIPTNCTV
EQMKAQVWMRAVEGHQTSDLFRKITPDQFLLLYQKKGQWYEIYDKHQIIQTLDCILYWKV
LQKKVGKIHVVEKPNPSEEVQEFQKRLNYLIGYDVTDVSNVHDDELEFARRRLVTPRTIE
VSCRDPKLYSMPVWTTSKPLPEYLLSRIVHNNIFLNIHRGTTSQKIKVAVDDMPDVILQS
FFTKMAKKKSLMNIPEDYSEQDFVLRVSGRDEYIVGETPIKNFHWIRQCLKKGDEIHLLL
DEPPDPNQDEVQKEEWPLVDDCTGVSGYHEQLTIHGKDHERVFTISLWDCNRKFRVKIIG
MDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTTAKPFTEEVLWNVWLEFDIKIKDLPKGA
LLTLQIYCGKTPAPSAKGNLHPHDSPSSDPKYKTQLLYYVNLLLIDHRSLLRTGDYVLHM
WKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHKIASDSQGDRAR
VEMPNQLRKQLEEIIATDLFNPLTPEDKELLWHFRYESIKHPKGYPKLLSSVKWGQQEQV
AETYQLLAKREAWDQSALDVGLPIQLLDCNFSDETVRTMAVQKLEGLEDDDVLHYLLQLV
QAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGC
GRAMLKDFLRQVQVTELLHKVTREIKTISAEKYDVTPQVIAQLKQKLERLQDNRFPECFR
VPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTSLSSETIGIIFKHGDDLRQDMLI
LQILRIMESIWEEESLDLCLLPYGCISTGNKIGMIEIVKDANTIAKIQQSTVGNTGAFKD
EILNQWLKEKCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITGSGNLFHID
FGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLRFQNFQDICVRAYLALRKHT
NLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKHEEDAKKYFLDQIEVCRDKGWTVQF
NWFLHLVLGIKQGVEKHSA
>A0A8C4U2F7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Falco tinnunculus|TrEMBL
MPPGIYCPTEFWAKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLHISTKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKTT
PKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQ
ALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFFLQVHLDHD
VFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLI
LEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHVCMKQETYLEA
LSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDM
LTLQMIQLMDILWKQEGLDLSDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRET
GQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAY
MILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALR
ESWKTKVNWLAHNVSKDNRQ
>H0UUY5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cavia porcellus|TrEMBL
MPPAMADILDIWAVDSQIASDGSISVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGKGLHEFDALEDPEVNEFRRKMRKFSEDKIQSLVGLSWIDWLKQTYPPEHDPSILE
NFEDKLYGGKLIVAVHFENSQEVFSFHVSPNMNPIKVNELAIQKRLTIHGKDDEASPGNY
VLQVIGRIEYVFGDYPLIQFQYIRNCVVNRTLPHFVLVECCKIKQMYEQEMIAIEAAINR
NSSNFPLPLPPKKTRIISHVWDNNKPFQIVLVKGNKLNTEEAVKVHVRAGLFHGTELLCK
TIISSEISGKNDHIWNETLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQ
TIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYIE
NATALHIKFPENKKQPCYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLSPREA
LELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALA
NRRIGQFLFWHLSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCIILSEL
YIEKCKYMDSKMKPLWLVYTNKVFGEDSVGVIFKNGDGKYSGFYSTKFLRRKYDLLCPFF
PFRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKECNSGD
DLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEEAYLILRRHGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKTDEEALKQFKQKFDEALRESWTTKVNWMAHTVRRDYRS
>A0A7J8I218|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Molossus molossus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTAAPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A671SHC1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPSAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYTMPLEAGSLE
SLIDKHEDDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGFRSDYVLRVSGKLEFLF
EDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIGSVIARKTSNPPLLLPPK
KRLPTASTLFPALQLIQGVLSFAYLAVRAGLFHGTELLCKTAVSSESSSRSEHVWNKTLE
FDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIPWVNTMVFDYRGQLKTGN
VLRKCLFFLCVADELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVFPVFDKGRGG
KKFYIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQL
QALLQIWPKLSPRDALELLDFNYPDQYVREFAVYCLRDMSDDELLQYLLQLVQVLRYEPY
YDCALSRFLLERAQSSRKIGHFLFWHLRSEMFMPAVSVHFALILEAYCRGCIPHIEVLKK
QVEALSKLKAVNELIKFGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLA
GINVERCKYMDSKMKPLWIVYNNKLLEGETVGIIFKNGDDLRQDMLTLQILRLMDLLWKE
ANLDLRIVPYGCLATGDHAGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKN
SGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKF
GIKRERVPFILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLT
AGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>Q4RVP5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tetraodon nigroviridis|TrEMBL
MPPGKYGMQEEWEKEGDQRIMMDFLLPTGIFLKFPVSRNDTIKIIKKMVWKNAQNEALYA
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCFLRLVAREGDRVEKLTNTQISQL
TGKGLHEFEAQKNHEVDEFRAKMRAFCEEKAQERQMLPWLEWMEYNFPCDLEPCCSPVDC
GATKSKNTKIFINVKFEACDESFMLQQDPQDLPVALMKAALKKKATVFRSVRQEPEDYTL
QVNGRWEFIYGRHPLSQFKVSGHEHPYAQCPQYIFSCLRNGQNPHLTMVHHSTIRKHQEE
QGHMCSQVYKGRSQSRPPPLPLKKNTSSLWSINEPFYIRLLHGSRVNAAEGMKLVVQAGL
FHGSELLCKVVTSSEVAVCSEPVWDQRLEFDISVSDLPRMSRLCFALYAVIEKNKKPRGT
KKKNKKAVGAFKVQLDCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTV
EKNPNVDSAAGLLIHFPNVRPHPLYYPSPEKILKQPQLLLFTFGACLCSLQHMKLKEIMD
NKNYTEIFEDEKELLWKLRDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNSRIGH
FLFWHLNLMLEAYCRGNIWHIKLLIKQNEALLKMKTLSDIVKTGSQKMTVDDLKLCIKQE
SYVETLSDLLSPLNPSVFLAEICADKCRFMDSKMKPLWLMYKSPWAQGDMMGIIFKNGDD
LRQDMLTLQMIRLMENLWKKEGLDLRMIPYGCLSTGDKMGLIEVVKNSDTIANIQRNSSN
SAATAAFNKDALLNWLKSKNPEGKLEKAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERA
YKILCRNGMLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEEEALKNFKVKFNEAL
RESWKTKVFPKNQAATVGPTAPPAAAGGTEPPAGRAALVLRSSADWRDVTPEQDASFSNT
PFKRSTEERKPGPGGMLAVPGLVSSVCAAAPPNHRSSQYREVMHIQCACIITINVGRATG
EAGMNREEAPGKSPEDMYIQQKVRVLLMLKKMGSNLTPSEEAFLRNYAGVVHSQMSQLPQ
HNIDQGKALKVPQVCTA
>A0A671L7M2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLFLPFWLCSKWHKTFSTGHHEFDSQKNHEVNE
FRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQSGKSHSGKKILVNVKFEGS
EETFVLQQDPQDLPMFLKRNALRKKSTVFRPAKQEKPEDYTLQVNGRWEFIYGKYPLCQF
KYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRTRAQSKPPPLPLKRQNTSSLW
SIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSNEVSVCSEPVWDQKLVF
DIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFS
LSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKLNELGMNC
EKVVATKEEHLKLREIVDNKNYTEFFEDEKELLWKLRKEVRQRYPESLPKLLLITKWNKH
EDVAQMVCLLRKWQELPAIHALELLDYSFPDPHVRSFTIRCLRNLRNDELFQYLLQLVQV
LKYESYLDCDLTCFLLERALSNKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSIFL
IKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPS
IVLCELCADKCKFMDSKMKPLWLMYKDKYDHVGIIFKNGDDLRQDMLTLQMIQLMDVLWK
TEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSK
NPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSK
FGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMK
AAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSFAKDN
R
>A0A671T7E7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPGVYGMQDVWEREGWQQVNMEFLLPTGIYLNFPVTCSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVCQMLPWDQWMEYNFPCDLEPCSVVAQS
GKSCSDKKIFVNVKFEGSEETFVLQQGPQDLPMFLKRNALRKKSTVFRSAKQEKPEDYAL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLEFDISVSDLPRMSRLCIALYGVIEKTKKRPTKKKNKSSDCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGMNGEKTVATKEEMVGLLRKWPELPAIHALELLDYSFPDPHARSFT
IRCLRKLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMH
VSSVSLRFGLILEAFCRGSIFHIKNLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMK
VCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDTLGIIFKN
GDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRN
NSNSAATAAFTNLTPRHSPDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQ
LFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKI
LCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKVRIAQTGIIYYP
>A0A3L8SEF3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chloebia gouldiae|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>Q4JLV3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cricetulus griseus|TrEMBL
FDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFVIGMPVCEFDMVKDPEVQDFRRN
ILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNN
DKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFL
EKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDSFTMPSYSRRISTATPYMNGET
TTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPR
WNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMA
LNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSR
EAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPLSEITEQEKDFLWSHRHYCVTIP
EILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRSFAVRCLEKY
LTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQ
RFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQP
DFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFK
NGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQC
KGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIM
VKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQEYTKTREFERFQE
MCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFTKQ
MNDAHHGGWT
>A0A7L2BWJ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alaudala cheleensis|TrEMBL
MELEDHEQPVVMREENKRRRRRMKPHCTPSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNPDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6P6M9U6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carassius auratus|TrEMBL
MQDVWEREGRQQVNMEFLLPTGIYLNFPVACNETISTIKKMVWKNARNEPLFSALSDPDA
YVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLINTQISLLIGKGHHE
FESQKNHEVNEFRMKMRTFCEERAQVRQMLPWNQWMEYNFPCDLEPCSVVAQSGKSCSVK
KIFVNVKFEGSEETFVLQQDPHDLPVLLKQNALRKKSTVFRSTKQEKPEDYSLQINGRWE
FIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRAQSKPPPL
PLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVISNEVSVC
SDPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFD
YKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPP
IEKLNDLGMNGEKASKEEHLKLKEIVDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKL
LLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLSDDELF
QYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVSSVSLRFGLILE
AYCRGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALS
DVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQDMLTLQM
IQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKD
ALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFG
HFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRQCCEQAYKILCRNGIL
FVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNW
MMHTFAKDNR
>A0A2K5RDM5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cebus imitator|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSAAASLSPMELIPIEFVLPTSQRSCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKAMHRSPGQIHLVQRRAPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKYLMDIPESQSERDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKAPAESPSSESKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCYPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIETLQKVTLDIKSLSAEKYDVSSQVIAQLKQKLENLQNSHLP
KSFRVPYDPGLKAGALAVGIIWMSPCGLLYREAVESVDGFLLSPCLITGYKSLNTRQFPF
HIILNQLEIFLITQ
>A0A672UU23|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
TRDRSTVPDYSRFSRFHPAVALAQVVWKHAQYEPLYHMLSDPEAYVFTCINQTAEQQELE
DEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLLIGKGLHEFDSVQDPEVNDFRTKM
CQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGTGPLHIPTKNIFVNSFTFQISPNE
FPITLMSYAIKKQATVFRHETLEKPEDYTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLT
PHLTMVHSSTIIAMRDEQTNCITSPPKTATKPPPLPKKKVKGGSDPAGSTSNHPLMEMLS
LCGNNTGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIE
KAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTV
QCNPNTESAAALVICFPSVASHPVYYPSFEQVGTFPTLSYDSHEQKLQLKEILERRSHTE
LYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALEL
LDFSFPDRYVGSFAVNSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRK
IGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKAS
SLKATKPQTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIV
FNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTG
LIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYC
VATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQ
QGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLA
LGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKNNRQ
>G1MY67|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Meleagris gallopavo|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQVNSIANPPKMA
VKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVSKDCP
IAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPN
VASHPVYYPSFEQLLELGRNGEQPRSAPEDPEEQKLQLKEILERRSHTELYEHEKDLVWK
MRYDIRDQYPQALAKLLTITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVG
SFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRS
EMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKE
MMHVCMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGV
GIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTI
ANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDR
HSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFE
RFRGYCEKAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKH
FRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>G1NLQ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Meleagris gallopavo|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQVRYFNQSSGSDQTNPKFIFNFHLLSVSLFWYWHCLVSFSLHLVSTTICYVVN
A
>A0A851Y9E2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eolophus roseicapilla|TrEMBL
MELEDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAANCTVEQMKAQIWMRALEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVIQKQNPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKVKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDPKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWRIPGKGEEQGSINADKLTSATNPDKENSMAISVVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGISGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C7HDP9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHEVFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKCPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGESSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNRETPCLELEFDYF
SSPVKFPDMTTVEGHANWTISRELGFSYYHALTDSDNEQLRQVCNRDPLSEITEQEKDFL
WRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMI
RDFAVRCLEKYLTDDKLSQYLIQLVQVVKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHL
KSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQ
MKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNIRLEECRIMSSAKRPLWLNWENPDIMSE
LLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCMSLGDCVGLIEVV
RSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDLAVDLFTRSCAGYCVATFIL
GIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQEC
TKTREFERCLPVT
>A0A7K4LPR1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crypturellus undulatus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSGNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHVFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIVGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
LPGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSALDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITEA
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSAHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A5F7ZR11|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca mulatta|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSLQALLQIWPKLPP
REALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLER
ALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLN
SLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKM
KPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLA
TGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTL
SCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYD
FIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C7HDB5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
QQSCLFILFDLDVLNKDTVGSLLQRFCFPLSGFIYRHLDFPLNASSEPLYGALSDADAYV
FTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLLIGKGLHEFD
SQKNHEVNEFRVKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEPGGIKTKGTK
KIFVNVKFEASDVSALFLWPFLLLISMFVLVNQSVTFLRQEKPEDYTLQVNGRWEFIYGK
YPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQLSKSRSLSKPPPLPVKKV
SGQPLGTTLVVQAGLFHGSELLCKVVTSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCF
ALYAVIEKAKKPRSTKKKNKKADCPLAWVNTMVFDYKDQLKTGEFLLSTWPSVPGDLLNP
MGTVEKNPNVDSAAGLLIHFPNIRPHPLYYPHFDKVHLILDLEKNGGKVIATKLKEIVDN
KNYTEFFEDEKELLWKLRGVVRERYPESLSKLLLITKWNKHEDVAQMVTFLQKWPDLPAL
HALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERA
LSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGNIYHIKSLWKQNEALNKMKALND
FVKSGWQKTSRQQMTDDMKLCIKQEAYKDALSYLLSPLNPSIKLSEICADRCKFMDSKMK
PLWLMYKNKWVQGDAVGIIFKNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLST
GNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLS
CAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDF
VHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYL
KDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDSRL
>A0A8C0FUM8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
ICLRLSRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHA
QYEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVI
NSQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEP
MAKGLGTVYAVLLALQESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYTLQVN
GKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMAAKPP
PLPKKKVKESSDPVGSSPCGFMVFPYFSFPQLVVQAGLFHGNEMLCKTVSSSEVNVCSEP
VWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVSEASDCPIAWVNVM
LFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVASHPVY
YPSFEGPAEHITYTWAVRGQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALA
KLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDQYVGSFAINSLKKLTDHE
LFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLI
LEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHVCMKQETYLEA
LSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDM
LTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATA
AFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLF
HIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILR
RHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWK
TKVNWLAHNVSKDNRQ
>A0A3Q1M2L5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos taurus|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASMSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A3P9KTS2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MHPGIYGMLEEWEDGDQEINMDFLLPTGIFLKFPVSRNDTIKHIKEMVWRNARSEALFSG
LGDPDGYVFTCINQTAEREELEEEFRRIRDVKPFMCVLRLVAREGNRQEKLTNTQITQLI
GKGLHEFETQKNHEVNEFRTKMRTFCEEKALERQYLPWQRWLEYSFPCDLEPCRTPSGFG
SVKMKSSKIFINVKFEASDESFMLQQDCHDLPLALMKSALKKKATVFRSLRQEPEDYILQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPQLTMVHHSTVSRFQEEQSRMCNQMFKSRSL
SRPPPLPLKRQNTSSLWSINEPFYIQLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTS
LDVTVCSEPLWDQRLEFDINVCDLPRMSRLCFALYAVIEKTKKPKSTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSMWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRP
HPLYYPSLEKIIDFEKNGDMACTHKEEHLKLKEIMDNKHYTEFFEDEKDLLWKLRTEIRE
HYPENLSKLLLVTKWNKREDVVQMVSLLKKWPDLPAIHALELLDYSFPDPAVRSFTVRCL
RKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASV
SLRFGLILEAYCRGNIHHIKILNKQNEALAKMRALSDFVKSGSQKMTVEDLKLCIRQETY
MEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNPSTPGDMVGIIFKNGDDLR
QDMLTLQMIQLMENMWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQLNSSNSA
ATAAFNKDALLNWLKSKNPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYK
ILCRNGMLFVNLFAMMKAAGLPELTCFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDNRA
>A0A7K6JG67|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Machaerirhynchus nigripectus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQVWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTPSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHECSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPVALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIVATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>H2LYJ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETCYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDFEVQDFRRNILNVCKDAVELRDANGPHSRALYVYPPNVESSQDLPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYSQLPTD
SFVMPSYCRRISTATSYMNGEAAPKSLWTISGGLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLNYDMYILDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYNHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEHF
SSPVKYPDMNAVEEHANWTISRELGFNYNTSGQSNRVARDHALTDSDSEQLKQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKFLADDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNRGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKGEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A3Q7SE35|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vulpes vulpes|TrEMBL
MEPQGREPRVVLREDRRRRRRMKARGPAAGLPSMELIPIEFVLPTSQRGSKAPETALLHV
AGHGNVEQMKAQVWLRALETSAAADFYQRLGPDHFVLLYQKKGQWYEIYDRYQVVQTLDC
LRYWQLLRRSPGQIHVVQRRAPSAATRAFQRQLTALIGYDVTDVSNVHDNELEFTRRRLV
TPRMLEVAGRDPRLYAMHPWVTSKPLPDYLRKRIPNNCVFIVIHRGTTSQTVKVSADDTP
GAILRGFFAKMAKKKALMGIPEGQSERDFVLRVCGRDEYLVGDTPLQNFQWVRQCLKNGE
EMHLVLDAPPDPALDEVRKEEWPLVDDCTGATGYHEQLTIHGKDHESVFTVSLWDCDRRF
RVKIRGIDIPVLPRHADLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFSIKIK
DLPRGALLNLQVYCSKAPTPAAKASADAPGPGSEARGKAQLLYYVNLLLIDHRFLLRRGE
YVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPE
ADRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWG
QQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHY
LLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLEA
YLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNL
PESFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLR
QDMLILQILRIMESIWETESLDLYLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNT
GAFKDEVLNHWLKEKCAIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGN
LFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLA
LRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKG
WTVQFNWFLHLVLGIKQGEKHSA
>A0A8C4RMT2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Erpetoichthys calabaricus|TrEMBL
MEQLNEDKEPVIVREDKKRRRGKMKAFVSSTNIITMDQIVVEFILPSYGKFSKTQESILL
DLTGNCTVEQVKTQLWMKAIEISECPDFYQKITPDQCILLYQKKGQWYEIYDKHQVFQTL
DCIRYWKALKKDVGKIQLVHRTQLSEESRQYQSYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRIVELANRDAKLYSMDHFITNKPMPEFLLSKISNNNILIVIHRERASQTIKVDLDD
TPKQILENFFTKIAKKRALLGISEEDSESDFILRVCGRDEYIFGDVPIKNFHWVRQCLKN
SDEVHLVLESPPDPDKDIVQKEDWSLVDDCTGVAGSHEQLTIEEKDHEKLFTISLWDCNR
KFRVKILAIDIPVLPRNSELIVFVEASIFHGQQLLAQQRTSSKPFTEEVLWNIWLEFDIK
IKDLPKGARLSLQVFCGKIQSQISKSNFQDSINFDSKSKNRLLYYVNLLLIDHRSLLRQG
EYILHMWKMPEKSEDHSSVNADKLTSATNPDKESSMAIVIMLDKYAYPVVLPKSLDSSGA
ESGRSARDMPNHLRKQFEDIVKTDPLYPLSPEDKELLWHFKNECMKCPKAYPKFLNSVQW
GKQAAVYTTHCLLENEDTWDRNKLDVGLAMQLLDCNFSDEKVRTMAVRKLENLEDDDVLR
YLLQLVQAVKFEPYHDSSLARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILE
AYLRGCGEAMLQDFKKQVEVTKALQKVAKEIKTVSAEKYDVSAQVVYQLRQKLEKLQSTG
FPDNFKVPYDPGVRAGQLVIEQCKVMASKKKPLWLEFRHADPTTISSDTIGIIFKDGDDL
RQDMLILQILLIMESIWETESLDLSLLPYGCISTGNKIGMIEIVKNATTIANIQQSTVGN
TGAFKDEVLNQWLRDKCLTEEKFQVAVERFVHSCAGYCVATYVLGIGDRHNDNIMIAESG
NLFHIDFGHILGNYKSFMGINKERVPFVLTPDFLYVMGSFGKKTSPLFQKFQEVCVKAYL
ALRHHTNLLIVLFSMMLMTGMPQLTSKEDIEYIREALTVGKNEEDAEKHFLDQIEICRDK
GWTVQFNWFLHLVLGIKQGVEKRSA
>A0A7J5ZAC3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dissostichus mawsoni|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAIDLRDCNGPHSRALYVYPPNVESSVELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNSQRVPCSNPRWNEWLNYEMYIPDIPCAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGMEDLLNPIGVTGSNPNKDHANWNISRELG
FNYCHTGLSNRLARDNPLTDTDNEQLRQVCNRDPLSEITEQEKDFLWRHRQDCVNMPEIL
PKILLAVKWNSRDEIAQMYCLLKDWPTIKPEQAMELLDCNFPDPMVRDFAVKCLDKYLTD
DKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFG
LLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLKQEKKDEAQKVQMKFLVEQMRRPDYM
DALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWENPDMMSELLFQNNEIIFKNGD
DLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGG
LKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKD
DGQLFHIDFGHFLDHKKKKFGYKRRVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYK
AYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDA
HHGGWTTKMDWIFHTIRQHAMN
>A0A8C8XKM4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera leo|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K8PCV4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cochlearius cochlearius|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKDNSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8D2ZCU7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQIPVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TLPFFAALGDMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVMKLVMRNCGRAERLLD
SKIGVLIGKGLHELDAMNDQEVKDFRSKTFRISEERMQGVQMMTCTEWLQSCFSPQLEPD
VADGAADWSADLKVIIHFDQSQDSASLKVPSSCTTTELMELAVRKWLTTHGPEEEAWRSQ
YVLRLSQCLEFLCGNHPLIQYKYIRTCVQAKESPHLTLVHNSTVKALFDKELSTIGAVVS
RKSSNPPLPLPPKRRTCVWDMSSPFKIVLVNASKVNAEETAKVQVRAGLFHGTEVLCKTA
VSSESSGRSDHTWKESTLEFDIPVSDLPRMTRLCFAIYAIMDKVKKQKSTKNTHINKYQT
IRKAGKVHYPIAWVNTMVFDYKGQLKTGDINLHCWSSFPDELEEMLNPIGTIQTNPYTEN
ATALYIHFPEYSSHPVIFPPFDKILEKAAEIAGASDCFPGRGGKKFHIELKEIMERDPLS
QLCENEKDLIWTLRWDCLVNFPQSLPKLLLSVKWSKHEDMAQLQALLQMWPKLSPRDALE
LLDFNYPDQYVREYAVPAQLPSLTLPSLPFSLSLPSSDEELSQYLLQLVQVLRYEPYYDC
ALTHFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVE
ALSKLKSVNELIKLGPTKNARSKTKDAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLL
SGINVERCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWK
EANLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKER
NTGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSK
FGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALML
TAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDN
RS
>A0A091Q7G8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptosomus discolor|TrEMBL
DFIMPPAVTDSLDIWAVDSQIGADGSVSVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEMDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRTTTSVWDVSSSFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAIYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHTWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEI
MGRDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8B6BQM7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mytilus galloprovincialis|TrEMBL
MPPVIVSPDLDVTSFQNDLGQLDIDFLLPNGICVPLQVDIDRPLDQIKQELWKQAANYPL
FQQLATFDKYGFLYISGEGQKEDVMDESVGISELRLAASFLKVVEKPADDKRKTIDRQIN
SLIGMKGSNYIQAQHSVSKAEISEFRQKMTTYCNNDVLKQANQDPTGLVYFEYKHPCRLR
STSELPPDVENMVIDYIVLTVIVQETGTSYKLRVKKLSTPDELVKMTVDKWSSKSGQKTI
NCNDYVLQVLGMNDFLYGDNPLVMFKYVYSCIVKNTAPEFWLKNKSSVLEKQEVSQPHKS
SRTSFQEERRNTVRSEKRSGHCVWDIHQNFYITLHTACNVQVPENCRNLVRLCVGVFHGP
DPLCSIQETKEVFVSQDGLCSFNDCINFDIKVQDLPQMSRLCFGLHCKKGKEPLLLAWAN
IPIFDYKSNLQKGKLKLPLWPRSELIQQEESYCFPVGTVATNPQGDCSMIEFSVPDFTKK
GSIYYPPIEKVLQCASDHMEEPGKCGSPTWRPNKNIVQQLDSILRANQYTILQTLDEQQK
QLIWWMRYDIRDKCSEFPHALLYVLYSVSWDNHIEVSKMQALLQTWPTLEADQALTLLDF
TFPDKYVRKKATEWLDELPDEELAQYLLQLVQALKYENYLNCDLVKFLLRRALQNRNIGH
KLFWLLKSDMHEPSVTVQYGLIIEIYLKANPSHMSILDRQQIILQKLKSITDIHTKAANL
KKKAKEKDDSPLQKVMQQSAYKEAFCKIYSPITLMYKLDKIVEKSCKVMDSKKKPFWLEW
TNDDEKGQNIQLIYKCGDDLRQDMLTLQILEVMDTIWQSEGYDLRLNPYGCVATGCEEGM
IEVVQKSLTLAGIQKWRKLGLDKRSLYDWLKHKNPSEHSLQRAVEEFKLSCAGYAVATYI
LGVGDRHNDNIMMKETGQLFHIDFGHFLGNKKTKFNINRERVPFILTSHFEYIIKDGEKK
PQNFTDFKEICERAYLIIRSRAHLLIQLFMMMLSSGIPQLNNVSDIDYIKEVLALNSTQE
EALEKFRKKFKEAQDNSWSTTVNWWFHMRVH
>A0A7L3TPR4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Uria aalge|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPLKMA
AKPPPLPKKKPNYGSFWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPHALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K8JUI1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lophotis ruficrista|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMEQISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTEFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQALSTKTNLQAHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTLQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A673J358|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMRDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGLCHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWDQWMEYNFTCDLEPCSVVA
QSGKSCSDKKIFVNVKSPGYAFHIFTLKKSTVFRSAKQEKPEDYTLQINGRWEFIYGKYP
LCQFKVSLKITPSSRLHSYIFFKLHIKASHFQTPGCIKCLKLNADEGMKLVVQAGLFHGS
ELLCKVVTSNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCIALYGVIEKTKKRPTKKKNK
SSDCPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPDLLNPMGTVEKNPNIDSTAGLLIRFP
NIRPHPLYYPPIEKTLILTNGTVFFQHLKLREIVDNKNYTEFFEDEKELLWKLREEVRQR
YPESLPKLLLITKWNKHEDVAQMVGLLQKWPELPAIHALELLDYSFPDPHARSFTIRCLR
KLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVSSVS
LRFGLILEAFCRGSIFHIKNLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQ
DTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDTLGIIFKNGDDLR
QDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSA
ATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETG
QLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYK
ILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRE
SWKTKVNWMMHTFAKDNR
>A0A2I3SG60|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan troglodytes|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFER
>A0A315UZW2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gambusia affinis|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFIEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIMSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLENFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCENVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVSLFDYMDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKVTVLLGFQAT
ELTETPCVELEFSRFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAT
DAEQLRSLCSRDPLYELSEQEKDFLWRHRHYCLNIPESLPKLLLSVKWNSRDEVSQMYCL
LKEWPLMEPESALELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLD
NPLARFLIKKALTNQRIGHFFFWHLKSEMHNKTISRRFGLLLEAFCRACGMYLKHLNRQK
ETCSQVEAMDKLVNLTDTLKQEKKDETQKTQMKFLVEHMSRPDYMESLQGFVSPLNPVHQ
LGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIM
ENIWQNQGLDLR
>A0A7K4XAD2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Regulus satrapa|TrEMBL
DSIMPPAVTDSIDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQA
HSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYTVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALGNRRIGQMLFWHLRSEIHIPAVSVQFSLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8J6GUA4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microtus ochrogaster|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
SFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWSEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPTKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPL
SEITEQEKDFLWSHRQVHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQA
MELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKAL
TNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDI
LKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRP
LWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGC
LSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFT
RSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQ
DFLIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDD
IAYIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A4W6CFA6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TLPLFSALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRISEERMQRVQMMTCAEWLQACFSPQLEPT
AGTAITDGVNDRLADLKVTIHFDQSQVRVCNLQQILLLMELALKKWLTTHGPEEEAWRGQ
YVLRLSQRLEFLCGDHPLIQYKYIRTCMQAKESPHLTLVHTSAVKAMFDKEISTIGAVVS
RKSSNPPLPLPPKRRVPTVSHTTCVWDVSNSFKIVLVNASKVNAEENAKVQVRAGLFHGT
ELLCKPAVSTESSGRSDHTWKESTLEFDISICDLPRMTRLCFAIYAVMDKVKKQKSTKNP
HINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDINLHCWSSFPDELEEMLNPIGTIQ
TNPYTENATALYINFPEYSSHPVVFPPFDKVRQLSVIGRGGKKFHIELKEIMERDPLSQL
CENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELL
DFNYPDQYVREYAVCCLRDMSSKLENILMLLSLILLSFLTSDEELSQYLLQLVQVLRYEP
YYDCALTHFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLK
KQVEALNKLKSVNELIKLGTTKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNP
NVLLSGINVERCRYMDSKMKPLWIVYNNKLMGGDTLGIIFKNGDDLRQDMLTLQILRLMD
LLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNW
LKERNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGN
FKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLF
ALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNV
AKDNRS
>A0A4W6FYL2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MDGQQTQVSDEEPKYLREETRRRRRKKAITSSSSASMDQISVEFILPTVARGGNSPDSLQ
LDVAGNWTVEQVKAQVWLKAVTSNLCPEFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVSNSHILVVIHIGTASQTIKVSID
DTPAQVLASFFTKTANKRVLLGIPDNMCEADYVLRVCGREEYLYGDKPLQNFNWIRQCLK
NGEEIHLVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDGKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQLICLSFHLSGKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEK
SEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDVAAVGEDVEGG
ERGQREMPNHLKKQFAAIVSTDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRWGK
QEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYL
LQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAY
LRGCGEAMLQDYRKQVEMTEALQKVTREMKAMSADKYDVTAQVVFQLRQKLETLQSSGLP
ESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQ
DMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGQLYQKTGVEDQ
>A0A7K9KAR0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicaeum eximium|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGSIKQVLWKQAQHEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAARRQQLSWAAWMEYNFPLQLEPMAKGPGT
ASLQIPNKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETLQKPEDYT
LQVNGKCEYLYGNHPLYQFQHIRRCLQRGRTPQLTMVHSSAIIAMRDEQSNAITSPPKAA
CKPPPLPKKKPNSGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVSDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKSGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAAEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRFVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHADTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A484CRF2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Perca flavescens|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMLLTLECLREATLITVKHELFKEARKYPLYN
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESCAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPCAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMTIIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDIDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQHCVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A484D283|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Perca flavescens|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRAIYVYPPNVESTQELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSSVKYPDMNAIEEHANWTISRELGFNYNLSGQSNRSARDHALTENDTEQMRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPSTRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A091MWZ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acanthisitta chloris|TrEMBL
MELEDYEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDRHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNTDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQDS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L2LTQ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hippolais icterina|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTNNKHTKAPEIILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQNPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A669D155|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MDRQQIQVSDEESQVPREESRRRRRKKAITSSCSNSMDQITVEFVLPTAARGGSGSDTLQ
LDVAGNWTVEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTCKPLPEHLLSKINNGHILVVIHIGTASQTIKVSID
DTPTLVLVSFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLK
NGEEIHLVLEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKQPQIPNSKGSSYQESTAGSSSLDGKTKSRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLP
KSRDVGRDWAVGGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHE
CMRVPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVR
SMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSKHYQQRYAVLLEAYLRGCGENMLQDFRKQVDMTEALQKVTREIKTMSADKYDVTP
QVVFQLRQKLENLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADST
TLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKK
SSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSE
DEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A669C342|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKSKNIKKIFINVKFEASDESFMLQQDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTITKYQEEQGRMCSQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKVPSPKRLHKTVTVKRNYFKLKEIMDNKNYTEFFEDEKELLWKLRTEVRDH
YPESLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLR
KLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASVG
LRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESYL
EALSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLRQ
DMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAA
TAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQ
LFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKI
LCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEALRES
WKTKVNWMMHSLAKDNRP
>A0A093GUX3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dryobates pubescens|TrEMBL
DFIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDTLQDPEVNDFRTKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVE
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISNPFKITLLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPIHYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8B7TYB8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Castor canadensis|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPMLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRIPNRALLVNVKFEGSEVSTKDMPLALMACALRKKATVFRQSLAEQPEDYALQVNGR
HEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPTPQVQKPRTKPPPV
PAKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVSVC
SEPVWKQRLEFDINICDLPRMVRLCFALYAVVEKTKKARSTKKKSKKADCPIAWANLMLF
DYKDQLKTGERCLYMWPSVPDDKGELLNPVGTVRSNPNTESAAALVICLPEVAPHPVYYP
ALEKILELGHHEERGRITEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQEHFPEAL
ARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTDD
ELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGL
LMEAYCRGSTHHMKVLMKQGEALSKLKSLNDFVKVSSQKTTKPQTKELMHLCMRQEAYLE
ALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYGGEEAGSAGSVGIIFKNGDDLRQ
DMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMAA
TAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQ
LFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTI
LRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRES
WKTKVNWLAHNVSKDNRQ
>A0A671WNR8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MDGKQIQVSDEEPRVVREETRRRRRKKAITSSSCSSMDQITVEFVLPTTARGGNSPDTVL
LDVAGNWTVEQVKAQVWLKAVTLNLCHDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTRKLLPDHLLSKVSNNHILVVIHIGTVSQTIKVSID
DPPVLASFFAKTANKRVLLGIPDDMCEEDFVLRVCGREEYLYGEKPLHNFNWIRQCLKNG
EEIHLVLESPPDPELDQVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRK
FRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLEFNIKI
KDLPKGARLNLQVNTPDNTAGTGKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKS
EESSSSINADKLTSATNPDKASAMAIAILLDKYCYPVVLPKSRDVGRDVGAGGEEAEGGE
RGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRWGKQ
EDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLL
QLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYL
RGCGEDMLQDFRKQVEMTEALQKVTREVKAMSADKYDITAQVVFQLRQKLENLQSSGLPE
SFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQD
MLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGA
FKDEILYQWLRDKCVSEDKFQQAVEKFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLF
HIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALR
HHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWM
VQINWFVHLVLGIKQGVEKRST
>A0A7K9G124|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Stercorarius parasiticus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTIFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSE
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A1A8QKC1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius pienaari|TrEMBL
MPPGKYGMQEEWEKEGDQNILMDFLLPTGIFLKFPVPRNDTIKNIKKMVWRNAKTEALYF
GLGDPEGYVFTCINDTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNSHISSL
IGKGLHEFEAQKNHEVDEFRSKMRTFCEEKALERHNLPWQQWMEYSFPCDLEPCCSPPVH
GGAKSKHTKKLFINVKFEACDESFMLQQDPLDIPVALMKSALKKRATVFRSVRQEPEDYT
LQVSGRWEFIYGNHPLG
>F6Q3H7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodelphis domestica|TrEMBL
MPPGVDCPMEFWSKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVARQGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAAHRQQLGWEAWMHYNFPLQLEPSSHGWGA
GTLRAPNRNLFVNVKFEGNEESFTFQVSPNDLPLALMACALKKRATVFRQSGLERPEDYT
LQVNGKYEYLYGNHPLFQFQYICHCLHKGLTPHLTMVHSSSILAMRDEQSNPPAQAPKLR
AKPPPIPVKKPSSVSLWSLEQPFCIELVQGSKVNADERMKLVVLAGLFHGNEMLCKTVSS
SEVTVCSEPVWRQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWSSVPDEKGELLNPMGTVRSNPNTESAAALVICIPEVAP
HPVYYPTLEKILELGKNGEHARFTEDEMLFLLRSWPELPVLSALELLDFSFPDRHVGSFA
IQSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMH
VPSVALRFGLIMEAYCRGSNHHMKVLMKQGEALNKMKALNDFVKVSSQKTTKPQTKELMH
VCMRQETYLEALSNVQSPLNPSTLLSEVCVEQCTFMDSKMKPLWIVYSNEEAAGGADSHV
GIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVSHSDTI
ANIQLNKSNMAATAAFNRTLSSILDVQGGEAQERAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERF
RSYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIHCISWHVLMPEPVSVGMGGL
>G1KBQ4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anolis carolinensis|TrEMBL
MMPPAMADTLDIWAVDSQIAADGSISVDCLLPTGIYISLDVPRDATICHIKQLLWKQAHS
YPLFHLLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLQLITRSCDPGEKLDSK
IGVLIGKGLHEFDALQDPEVKEFRIKMRRISEEKMQSLVRLSWMDWLKHTYPPELEPAVQ
ENLQDKLYGGNLVVAVHFDNCQDVFSFQVSPNIIPIKLNELAIRKRLTIHGREDEEVDPS
NYVLQVSGRLEYVFGDHPLIQFQYLHRCVMSRTLPQLTLIECSTIKKMCEQEMIAIEAAI
NRKPSNLPLPLPPKKSRVTQSVWDISQPFKVLLVNGSKLNTEETAKVHVRAGLFHGTELL
CKPIVSSEISGRNDHLWNEPLEFDINVCDLPRMARLCFVVYAVMDKMKNKKSAKSLNPSK
YQTIRKAGKVHYPVAWVNTMVFDFKGQFKTGDLVLHSWSSFPDELEEMLNPMGTVQTNPY
TENATSLQIKFQEYSKFPIYYPPFDKILEKAAEIARSSDSSGMAGRGGKKFYIELKEIME
RDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPP
REALELLDFNYPDQYVREYAVSCLRQMSDEELAQYLLQLVQVLKYEPFLDCALSRFLLEK
AMANRRIGQMLFWHLRSEVHIPAISVQFGVILEAFCRGSIAHMKVLSKQVEALNKMKTLN
NLIKLNAMKQSRAKGKEAMHTCLKQRVYKEALSDLQSPLNPSVLLSELYVEKCKYMDSKM
KPLWIVYNNKVFGGDLVVIMFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLA
TGDLSGLIEVISASETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEAFTL
SCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYD
FIHVIQQGKTGNTEKFGRFRQCCEEAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKNDEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C4MT30|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Equus asinus asinus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLV
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPLAGNWGA
STLRFPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRLEYLYGSYPLCRFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPTPQVQKPR
TKPPPIPVKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRNNPNTESAAALVISLPEVAP
HPVYYPALDKILELGRPGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKATKPHTKELMHLCMR
QETYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A3B3UU00|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia latipinna|TrEMBL
MPPGKYGTQEEWEQDGDREIYMDFLLPTGIFLKFPVSRNDTIRNIKKMVWKNASREPLFF
GLGDPDLYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRSEKLTNAQISLL
IGKGLHEFEAQKNHEVDEFRTKMRTFCEEKSLERQNLPWQRWMEYSFPCELEPCSSPATG
GSSKSKHGKKLFVNIKFESSDESFMLQQDSQDLPVALMKSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGQHPLCQFKYIFFCMRNGQNPQLTMVHHSTISKYQEDQGRVCSQMYKTR
SLSRPPPLPLKKQNTSSLWSINEPFYIHLVQGSKVNADEGMKLVVQAGLFHGSELLCKMM
TSSEVTVCSEPLWDQRLEFDINVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGDFLLSMWPSVPDDKSDLLNPMGTVQKNPNVDSAAGLLIRFPNI
RPHPLYYPPLEKTIDPEMNGNTDFPSKDEYLKLKEIMDNKNYTEFFEDEKELLWKLRIEV
RDYFPECLSKLLLITKWNKREDVVQMVSLLKSWPELPAIQALELLDYSFPDPAVRYFTIR
CLKKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALTNRRIGHFLFWHLKSEIHVA
SVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDIVKTGSQKMTVDDLKLCIRQE
SYLEALSDLLSPLNPSVILFEICADKCRFMDSKMKPLWLMYKNPLEQADMVGIIFKNGDD
LRQDMLTLQMIRLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEIVKSSDTIANIQRNNSN
SAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEKA
YKILCRNGTLFVNLFAMMKAAGLPELSSSKDIQYLKDSLALGKSEDEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A8B7F1Y3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcebus murinus|TrEMBL
MELENYEQPVVLREDNVRRRRRMKPRSAAASLSPMELIPIEFVLPTSQRHSKSPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQIHLVQRRAPSEETQVFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPSVTSKPLPEYLSKKIANNCIFIIIHRSTTSQTIKVSAEDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDGVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPILSGRVSADTSGPESKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPSPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPIEEKVRSCFSPTLKTPHELSSCLGSNSGCRFSKDLPTSCLLPYW
>A0A2R9B610|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan paniscus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C3YD83|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Catagonus wagneri|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLVSSQISLL
IGKGLHEFDSLHDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPVPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRHGEHGRFTEEEHLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNRHEDVAQMLHLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGDALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q2ZR79|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Kryptolebias marmoratus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGSHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPTD
NFTMPSYARRISTATPYMNGETATKCLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMSIVEEHANWNISRELGSNYGHTGLSNRLARDNPLTESDNEQLRQVCNKDPL
SEITEQEKDLLWSHRYHCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMMREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHALHQWLKDKNKGEMYDQAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A7K9DYY0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Baryphthengus martii|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEIILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNTWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITTD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCIIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGESEENAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A812CJN6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sepia pharaonis|TrEMBL
MFINMFSCKEKKDKGRNYCERKGWNKKKKIRKKFDYALAWGNLQMFDFNHRLLSDKGRIH
LWPMPQGMDDLLNPIGIPGSNPNQDCPCLDIEFDKFSHSVTFDMEKFDEYCRRNSQDGYT
QDSYVEHRPPDEKQMKQLEELVSRDPLSELSEQEKDFVWKLRNTCLVLPHSLPKLLNSVK
WNDRGDVAEIYRLLQKWPTLSPEDALELLDCSYMDTNIRNFAVDCLNKGLTNDKLSQYLL
QIVQALKYEPYLDNCLTRFLLKRALLNQRIGQFFFWHLRSEMHETSIRLRFGLILEAYCR
GCGAFLRNLLKQLEALDKLAKLSDKMKSDFMREEDQKRFLTEQLSQADYQEALQRFISPL
NNSHMLGDILVQHCYLKSSKKRPLWLVWQNPDPLAEYWLSYYKLIFKNGDDLRQDMLTLQ
VIRIMDSIWKNEGIDLRMIPYGCLSTGKEMGLIEVVPAAKTVMAIQHRGGKAASMQLDSS
QLHKWIRERNPKEQYDVAIDTFTKSCAGYCVATFVLGIGDRHSENIMLTEEGQVFHIDFG
HFLNHKKKKFGINRERVPFVLTEDFIKVIAKGADQPQKNKLFEDIPELQSLDDIGYLRKT
LAVEKSEQEAATYFQEHSGWHHHLYAGHFCLLNVSTKSCSLLIPSSLFFIHFFFSVLLSL
SLSLFLPLFSLSLSLLSLSLLSLSSLSLSLPLFSLSLSASLLSLSLCLSSLSLSLCLSSL
SLSLSLFSLSLSLSLSLSPLSLSLSLSLSLSLLSLLFFSLSLSFSLSLLSLSLSLSLSLS
LCLSLSSLSLSLLSSLSLFLSSLSLFSLLSLSL
>A0A7L1JMY3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rynchops niger|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVTS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C8RIK9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pelusios castaneus|TrEMBL
MPPAMTDIFDIWAVDSQIGGDGLISVDFLLPNGTYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVQEELEDETQRLCDVRPFLPVLKLITKNCDPGEKLDSKI
GVLIGKGLHEFDALEDPEVKEFRSKMRRISEEKLQSLVGLSWVDWLTHTYPPEQEPSIPE
NFQDKLYGGNLVVAIHFDKCQDVFSFQVSPNINPIKLNEMAIRKRLTIHGKADEVDPSGY
VLQISGRLEYVFGDRPLIQFQYIRNCVINRTLPHLTLVECSSIKKMCEQEMITIEAAINR
KSSNLPLPLPPKKTRSATQLTQSVWDISNSFKIMLLKGNKLNTEETAKVHVRAGLFHGTE
LLCKPIVSAEISGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKTINP
SKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDLLLHSWTSFPDELEEMLNPMGTVRTN
PYTENATVLHIKFQEYSKLPTYYPPFDKILEKAAEIAKSSDNVGMAGRGGKKFYIELKEI
MERDPLTQLCENEIDLIWTLRYDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWSKL
PPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFFDCALSRFLT
ERALANRRIGQMLFWHLRSEMHIPAVSIQFGVILEAYCRGSVAHMKVLSKQVEALNKLKT
LNNLIKLNSMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILAELYVEKCKYMDS
KMKPLWIVYNNKMFGGDLVGVIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRVLPYGC
LATGDHSGLIEAVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEEAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3B4U5Q8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Greater amberjack|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKANTHCNKTTIIYFTNTFSVNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLS
QEQLKMCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYS
QLPMDNFTMPSYARRISTATPYMNGETATKALWTINGTLRIRILCATYVNVNIRDIDKIY
VRTGIYHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGA
KEEHCPLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLEL
EFDHFSCPVKFPDMTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVC
NRDPLSEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKP
EQAMELLDCNFPDPMIRDFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLK
KALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINL
TDLLKQEKKDEAQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRMMSSA
KRPLWLNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLP
YGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAID
LFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFV
LTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQS
FDDIAYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A3B4U5Q8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola dumerili|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKANTHCNKTTIIYFTNTFSVNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLS
QEQLKMCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYS
QLPMDNFTMPSYARRISTATPYMNGETATKALWTINGTLRIRILCATYVNVNIRDIDKIY
VRTGIYHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGA
KEEHCPLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLEL
EFDHFSCPVKFPDMTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVC
NRDPLSEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKP
EQAMELLDCNFPDPMIRDFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLK
KALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINL
TDLLKQEKKDEAQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRMMSSA
KRPLWLNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLP
YGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAID
LFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFV
LTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQS
FDDIAYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A4W5RCS3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MEIILSDEEEPQPVVLREENRRRRRKMKAFTSTFSVTMDQIPIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKQLPEYLLTKVTNSHILLVIHRNKASQTIKMSV
DDTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNQPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERIFTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFN
IRIRDLPKGARLSLQVSCGKAQTQISKGTYQDNGGSPTKSRLLYYVNLLLVDHRSLLRQG
EFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMVVAILLDKYCYPVALPKSREGKER
GQREMPNHLRKQFESIVETDPLHPLSQEDKELLWHFREECMRHPRAYPKLLGSVRWGRQE
AVLTTHGLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLETLGDDDVLRYLLQ
LVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLR
GCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQVVFQLRQKLENLQTSGLPES
FRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTTLSSDTIGVIFKDGDDLRQDM
LILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSVVGSTGAF
KDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLGVGDRHNDNIMITESGNLFH
IDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVRAYLALRQ
HTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEEAQRHLLDQIEICRDKGWTV
QFNWFLHLVLGIKQGVDKRSA
>A0A8C2Z1D4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MPSGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNASSEALFG
ALGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRMFCEEKAQERQMLPWQQWMKYSFPCDLEPCCSPPEY
GIIFVKFETNQRMIQDPQDLPVALMRSALKKKATVFRSLRQEPEDYTLQVNGRWDFIYGK
HPMCQFKYIFSCLRNGQNPYLTMVHHSTIHKYQEDQGSMYNQVYKSRSLSRPPPLPLKKV
RVQRTTVLVVQAGLFHGSELLCKVVTTSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFA
LYAVLEKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDKSDLLN
PMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPLDKYMKLKEIMDNKNSTEFFEDEKELL
WKLRTEVRDHFHESLSKLLLITKWNRHEDVVQLVSLLKNWRDLPGIHALELLDYSFPDPA
VRSFTIRCLRKLSDNELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHL
RSEIHVASVSLRFGLILEAYCRGNIHHIRLLTKQNEALGKMKALSDFVKSGSQKMTADDL
KLCIRQESYLEALSDLLSPLNPSIILAEICADKCRFMDSKMKPLWLMYNPGAQEDMVGII
FKKGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANI
QRNSSNSAATAAFNKDALLNWLKSKNPEDKLDPAIEEFTLSCAGYCVATYVLGIGDRHND
NIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFR
EYCERAYKILCRNATLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKV
KFNEALRESWKTKVNWMMHSLAKDNRP
>A0A3Q1BA85|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amphiprion ocellaris|TrEMBL
MPPGKYGMQEEWEKEDQQITMDFLLPTGIFLKFPVSRNDTIKSIKKMVWKNARSEALYSA
LGDPDGYVFTCINQTAEREELEEESRRLSDVRPFMCVLKLVAREGDRVEKLTNTQISQLI
GKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERESLPWQQWMEFSFPCELEPCCAPPESS
SVKPKNSKKIFIQIKFESCQESFMLQQDPQDLPVALMKSALKKKATVFRSVRQEPEDYTL
QVNGRWEFIYGKHPLCQFKYIFSCLRNGQNPHLTMIHHSTIVKYQEEQSKVCSQVSKSGS
LSRPPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
TSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNIDSAAGLLIRFPNIR
PHPLYYPPLDKISDMEKNGDAVYATKDEYTKLKEIIDNKNSTEFFEDEKELLWKLRTEVR
DRYPESLSKLLLITKWNKREDVVQMVSLLRHWPDLPAISALELLDYSFPDPAVRSFTIRC
LKKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVAS
VSLRFGLILEAYCRGDIHHIKLLTKQNEALGKMKALSDIVKSGSQKMTVDDLKLCIRQES
YLDALSDLYSPLNPSIFLADICVEKCRFMDSKMKPLWLMYLNPSLQGDMMGIIFKNGDDL
RQDMLTLQMIQLMENLWKTEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNS
AATAAFNKDALLNWLKSKNPEDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRET
GQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAY
KILCRNGTLFVNLFTMMKAAGLPELTSFKDIQYLKDSLALGKSEDEALKNFKVKFNEALR
ESWKTKVNWMMHSLAKDNRP
>A0A8C2ZW33|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
RELDEEPKVLREDTRRRRRKKAISSSSGASMDQITVEFVLPTAARGGSGPDTLPLEVAGN
WTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDCIRY
WRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPR
RIELSDRDAKLYSMDPWVTRKPLPEHLLTKVSNAHVLMVIHIRTASQTIKVSIDDTPTLC
SVCVEGSWEVETDHSCSYVEMVEEYLYGDEPLQDFNWIRQCLKNGDEIHLVLEMPPDTDL
DLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVLGIDIPSLPK
IPEFIVFIEASIFHGQQLLAQERTSSKTFSEEVLWNCWLEFNIKIKDLPKGARLNLQVVC
GKQPLTPNSKGTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEESSSSINADKLT
SATNPDKASAMAVAILLDKYCYPVVLPKSRNAGNRDDGGRDREMPNHLKKQFAAIVATDP
LHPLSPEDKELLWHFRHECIRDPRAYPKLLGSVRWGRQEDVLATHRLLERSSAWDSSGLD
VGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLK
RALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRKQVEMTEALQ
KVTREMKAMSADKCDITAQVVFQLRQKLETLQLSGLPESFRVPYDPGLRAGALMIEQCKV
MASKKKPLWLQFKRADPTTLSRDPIGIIFKDGDDLRQDMLILQILLIMESIWETETLDLC
LLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFKDEILSQWLRDKCVSEDKFQQ
AVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWV
PFVLTPDFLYVMGTSGKKSSPHFQKFQVSTGLFTWCWGSSRVWRKGPLRTLGLSACFFSI
>I3ME19|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ictidomys tridecemlineatus|TrEMBL
MASKADHNHSSQMLWHEAQNEPLFHMLSDPKAYVFTCVNQTAEQQELEDEQQRLCDVRPF
LPMLRLVTREGDRMEKLINSQISLLIGKGLHEFDCLQDPEVNDFRTKMRQFSEEAASRRQ
QRGWEAWLQYSFPLQLEPSTRSWGDSNTSQISNPDLLVNVKFEGSRESFTIQVSTKDVPL
ALMACALQKKAKMYQNLTMEQPEDYVLQVNGRHEYLYGSYLLCQFKVRGYKPRGAQSLGD
TAHGSPWKLSPNGLGEQCPVVSSKSTFMAPLHLEPPAEVDLLSHFWEERIGTLDGMGPSL
PHPCPVPLPQLVVQAGLFHGNEMLCKTMSSLEVSVCSEPMWKQHLEFDIHICDLPRMARL
CFALYAVMEKAKKVHSSKKKPKKEVGWCLWMLGVKIQAARKGSFWLNYLNSGRKEIAGPS
PPPGSNLETFHAVWIFSPGWPGDWFHSQVYLLQILELGRHREHGPTTKEEKLQLQGILEQ
RGLGELYEHEKDLVWKMRHEVKEALAHLLLVTKWNKHKDVAQMLYLLCSWPELPVLNALE
LLDFSFPDCHVGSFAIRSLQKLTDDELLQCLLQLVQVLKYKSYLDCELTQFLLDRALANR
KIGHFLFWHLRSEMHVPSVALHFGLIMEAYFRGSTHHMKVLMKQAEALSKLKALSDFVKV
SSQKTTKPQTKELMHLYMRQDTYLEALSHLQSPLDPSTMLAEVCVERCTFMDSKMKPLWI
MYSSEEADSGDSVSIIFKNGDDLRQDMLTLQMIQLMDALWKQEGLDLRMTPYGCLPTGDC
TGLIEAVQHSDTIANIQLKQSNLAAMAAFNKDALLNWLKSKNPG
>A0A8C2XBA5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MPSGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNASSEALFG
ALGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRMFCEEKAQERQMLPWQQWMKYSFPCDLEPCCSPPEY
GSVKSKNNKKIFINVKFEACDESFMLQQDPQDLPVALMRSALKKKATVFRSLRQEPEDYT
LQVNGRWDFIYGKHPMCQFKYIFSCLRNGQNPYLTMVHHSTIHKYQEDQGSMYNQVYKSR
SLSRPPPLPLKKQNTSSLWCISEPFYIHLLQGSRVNAGEGMKLVVQAGLFHGSELLCKVV
TTSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVLEKAKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIR
PHPLYYPPLDKISGGNMENNGDTTIATKEEYMKLKEIMDNKNSTEFFEDEKELLWKLRTE
VRDHFHESLSKLLLITKWNRHEDVVQLVSLLKNWRDLPGIHALELLDYSFPDPAVRSFTI
RCLRKLSDNELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLRSEIHV
ASVSLRFGLILEAYCRGNIHHIRLLTKQNEALGKMKALSDFVKSGSQKMTADDLKLCIRQ
ESYLEALSDLLSPLNPSIILAEICADKCRFMDSKMKPLWLMYNPGAQEDMVGIIFKKGDD
LRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSN
SAATAAFNKDALLNWLKSKNPEDKLDPAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERA
YKILCRNATLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A8C7V002|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
IELQVSDEEESQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIEGAALWATLCCLPVTNSHILLVIHRNKASQTIKVSIDDTPVQVLQTFFTKI
SNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCLKNGEEIHLVLESAPN
PGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDCHRKFRVKVLGIDIPA
LPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFNIRIRDLPKGARLRSP
VGGGSGSHDCNKTKSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLT
SATNPDKASSMAVAILLDKYCYPVALPKSREGERGQREMPNHLRKQFEAIVETDPLHPLS
QEDKELLWHFREECMRHPRAYPKLLGSVRWGRQEAVLATHRLLERSSVWDRSVLDVGLAM
QLLDCHYSDAHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRS
KRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTRE
IKAMSAEKYDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKK
RPLWLQFKRADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYG
CISTGNKIGMIEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERF
VFSCGGYCVATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLT
PDFLYVMGTSGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDI
EYIREALTVGRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A852MLH8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pteruthius melanotis|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSNSFSSMELISIEFILPTSNKHTKTPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTADFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRMCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDSPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERIFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNIQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVRVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRIPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIVFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDAATIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C9RRB8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHQ
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKESVDLRDASGPHSRALYVYPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKESLYSQLPTD
TFAMPSYARRISTATPYMNGEASAKSLWTINGTLRLRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIADIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGITGSNPNKETPCLELEFDYF
GSPVKFPDMATIEEHANWSISRELGFNYCHAALSNRLARDNTLTDIDSEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPVIKPEQAME
LLDCNFPDPMIREFAVHCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEAVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDLAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVICKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHLCST
>A0A3N0Y0Y0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabarilius grahami|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSPDLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKIAHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYFLEKYPLSQYKYIRSCITLARLPHLMLVSKDSLYSQLPAS
GFMAPSYSRRTPQPSPCPGGGDPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDEQQIEEHANWSISRELGYSYCLGLSSRLACDSTISQADAEQLRVLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQVRISISTQLYPSIRSSL
IRVCAQIYCLLKDWPLMQPESALELLDCNFPDPMVREFALRCLIQGLTDDKLSQYLLQLV
QVLKYEMYLDNPLARFLIKKALTNQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACG
MYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQKTQMKFLVEHMSRPDYMEALQGLEECRI
MSSAKRPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDL
RMLPYGCLSIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIKEKNKGEAYD
RAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRER
VPFVLTQDFLIVISKGVQECSKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMP
ELQSFDDIAYLRKTLALEKNQQDALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A8C2SZ42|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coturnix japonica|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
NFQDKLYSGNLVVAIHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEIDPAD
YVLQVSGRLEYVFGDHPLIQFQYIHNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEVAIN
RKSSNLPLPLPPKKTRATTSVWDICSPFKIVLLKGNKLNTEENAKVHVRAGIFHGTELLC
KTIVSTEISGRSDHAWNEVLEFEINVCDLPRMARLCFAVYAVMDKTKTKKSTKSMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGEFILHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCKYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A087VG60|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balearica regulorum gibbericeps|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSSELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSKLQSFDDIAYIRKTLAL
DKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K6V726|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Notiomystis cincta|TrEMBL
MELGDPEQPVVMREENKRRRRRMKPHCASSSFSSMELIPIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAVETSQTADFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVEEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKYKTQLLYYVNLLLIDHRFLLRT
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISVVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A672ZT80|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
SWCTNYFLQCPVVLREENRRRRRKKAITSSSCTSMDQIAVEFVLPTAARGGNSPDTLQLE
VAGNWTVEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLD
CIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKL
LTQRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVCNGFILVVIHISTASQTIKVSIDDT
PAQVLSSFFTKTANKRVLLGIPENTGEKDFVLRVCGRYKEYLYGDKPLQNFNWIRQCLKN
GDEIHLVLETPSDPEADLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNR
KFRVKVLGIDIPSLPKVPELVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIK
IRDLPKGARLNLQSHKGKFQVYSSKAQNLIPVCCLSGKTKSRLLYYVNLLLIDHRSLLRQ
GEFILHMWKMPEKSEESSSSSINADKLTSATNPDKASSMAITILLDKYCYPVVLPKSRDV
CRDGGTWGEEAEGGERGQREMPNHLKKQFEAIVATDPLHPLSPEDKELLWHFRHECMRHP
RAYPKLLGSVRWGKQDDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVR
KLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQS
MHYQQRYAVLLEAYLRGCGEAMLQDFRKQVEMTEALQKVTREIKAMSADKYDVTAQVVFQ
LRQKLETLQLSGLPESFRVPYDPGLRAGTLLIEQCKVMASKKKPLWLQFKRADPSTLSKD
PIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDAT
TIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGD
RHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHF
QKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRCEDDAQR
HLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A8B9TW56|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GLLHTPTKNIFVNVKFQSGGESFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANTPKMS
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPNVAS
HPVYYPSFEQLLELGRNGEPPRTQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYP
QALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFITNCSKYL
LQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYC
RGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCMKQETYLEALSHLQ
SPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIFKNGDDLRQDMLTLQM
IQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKD
ALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFG
HFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLL
FLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNW
LAHNVSKDNRQ
>A0A8C4R4J0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eptatretus burgeri|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMFVTIECVREATLASIKRELFREARKYPLGH
LLQAEGTYIFVGVTQEAEREEFYDETRRLCDLRLFQAILKVVEPVGNREEKMLNREIGFA
IGMPVCEFDLLKDPEVQEFRRNVLAVCKDAVEARDANGTHSLALYVYPPDIESSPDLPQH
ILNRLDKGYIIIVIWVIVSPSNDKQKYTVRVPHDATPEQVIAEAIRKKTRSMALSAEQLR
LCVNEYQGKYILKVCGCDDYLLERFPLSQYKYIRSCMALTRLPNLMLMTKESLHTQLPST
AFSLPWYARRVSVAPAYMNGESSAKSLWMVTGPLRLRVLCATYVNVNVRDIDKIYVRTGI
FHGGEPLCDNVNTQRVPCSNPKWNEWLTYDIYVADLPRAARLCLSICSVKGRKGGAKEEH
CPLAWGNVNLFDYMATLVAGKMALHLWPVPHGLEDLLNPIGISGSNPNKQETPCLEVEFE
WYNGVVKFPDIAMIEDHGRRSLQRDLHSLSSLGSRGGKDGEPSEPDREQLRSICNRDALS
DITEQEKDLLWRYRQHYHNIPEVLPKLLLAVKWYSRDETAQVYWLLKDWPLLRPELALEL
LDCNYPDPRAREFAGKCLEAGLTDDRLSQYLIQLVQVLKYEQYLDNHLARFLLKKALTNQ
RIGHFFFWHLKSEMHLKYVCQRFGLLLEAYCRTCGMYLKHLNRQVEAMDKLTNLTDMLKQ
EKKDETQKVQMRFLAEQMRQPDFMEALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLWL
NWENPDIMAELLFQNNEVIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRYEDMYTTKL
WQCFMTFMLSFFKLPCVRANICYHNNRDKRFNPILNSSSLGWSLFFLPECSHTAAYPLGT
VWDSSRWCRTRVPSCRSNAKVVLRVLSSSLATLCTNG
>A0A8B9VJY6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas zonorhyncha|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GLLHTPTKNIFVNVKFQSGGVNFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYT
LQVNGNHGSFVNGSNPRGLTVFSYFFSPQLVVQAGLFHGNEMLCKMVSSSEVNVCSEPVW
KQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVSKDCPIAWVNVMLFDY
KDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPNVASHPVYYPSF
DKPFGLRLSPLYALFCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQAL
AKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDN
ELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGL
ILEAYCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCMKQETYLE
ALSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIFKNGDDLRQD
MLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVAT
AAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQL
FHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMIL
RRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESW
KTKVNWLAHNVSKDNRQ
>A0A7N5ZQ93|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
YLSSSPNDEEPVVLREEIRRRRRKKAITSSSSISMDQITVEFVLPTATWGSNPDSLQLEV
AGNWTVEQVKAQVWLKAVTSNLCPEFYQRFSPDHCILLYQKKGNLCEIYDKHQVFQTLDC
IRYWRALKKDVGKIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLL
TPRRIELCDRDPKLYSMDPWVTRKPLPEHLLSKVSNGHILVVIHMSTASHTIKVSIDDTP
VLASFFNKTANKRVLLGIPDNVCETDYVLRVCGRYEYLYGDKPLQNFNWIRQCLKNGEEI
HLVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRV
KVLGIDIPTLPKVPEFVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKIKDL
PKGARLSLQVNSNINLKADRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEESSSSIN
ADKLTSATNPDKESSMAIAILLDKYCYPVVLPKSRDVGRDVGAVGEESEGGERGQREMPN
HLKKQFEAIVTTDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVKWGKQEDVLATHR
LLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKF
EPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEAML
QDFRKQVEMTEALQKVTREIKTMSADKYDVTAQVVFQLRQKLEILQSSGLPDNFRVPYDP
GLRAGALMIEQCKVMASKKKPLWLQFKKADPTTLSKDPIGIIFKDGDDLRQDMLILQILL
IMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFKDEILYQ
WLRDKCVSEEKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHIL
GNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTNLLII
LFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQINWFVH
LVLGIKQGVEKRST
>A0A7K7QL05|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecile atricapillus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDSPPDPNEDEVRKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEIWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6J2BD80|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zalophus californianus|TrEMBL
MWLSTRFRQNLFQVMSGMELKHHEQPVVLREDNGRRRRRMKPRSSAASLSSMELIPIEFV
LPTSQRNSKTPETALLHVAGHGNVEQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQKK
GQWYEIYDKHQVVQTLDCLRYWQVLHRSPGQIHVVQRRAPSEETLAFQRQLTALIGYDVT
DVSNVHDNELEFTRRRLVTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFII
IHRSTTSQTIKVSADDTPGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVG
ETPIKNFQWVRHCLKNGEEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHG
KDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKP
FTEEVLWNVWLEFSIKIKDLPRGALLNLQIYCSKAPALSGKASAETPGSESKGKAQLLYY
VNLLLIDHRFLLRHGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNY
CHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESL
KHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAI
AVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEI
AQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQV
ISQLKQKLENLQNSSLPESFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTAL
SNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVK
DATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLG
IGDRHNDNIMITETGCLRQGLPSPSSPHKPADHPVLHDADDGNAPVNKQRRYRIYSGRPN
SGEE
>A0A8C3KDC2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calidris pygmaea|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMTKGLGA
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQMTAKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADER
MKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVI
EKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGT
VQCNPNTESAAALVICFPSVASHPVYYPSFEQVGDGDAVLGAQKFPSFAGAGTYGVTGNE
EPFSDSLLSPVYALSCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQAL
AKLLIITKWNKHEDVAQVRMLGWASWPELPVLNALELLDFSFPDRYGDCEQDNELFQYLL
QLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCR
GSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHVCMKQETYLEALSHLQS
PLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMI
QLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDA
LLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGH
FLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLF
LHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWL
AHNVSKDNRQ
>A0A6J2UXV9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chanos chanos|TrEMBL
MPPGVYGMQDVWENEGREQVTVDFLLPTGIYLSFPVSHSDTIGAIKKMVWKNARSEPLFS
ALGDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPVLRLVAREGNRVEKLINTQISLL
IGKGLHEFDAQKNHEVDEFRTKMRLFCEERALERQLLPWYQWMEYSFPCDLEPCSIVTQS
GKNRNVKKIFVNVKFEASEESFMLQLEPHDLPVTLVKSALKKKATVFRPVKQEKPEDYTL
QVNGRWEFIYGKYPLCQFKYIFSCLHGGLTPHLTMVHHSTIVKYQEEQGIINNHISKSRS
SSKPPPLPLKKQNTSLLWSIQEPFYVQLVQGARVNADEGMKLVVQVGLFHGSELLCKVVT
SNEINVSSEPLWDQKLQFDIGVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPLA
WVNTMVFDYKDQLKTGEFWLSTWPSVPDDKGDLLNPMGTVERNPNIDSTAGLLIRFPNIR
PHPLYYPPLEKINELGTNGERVATTKEEHLKLKEIVDNKNYTEFFEDEKELLWKMRSVVR
EKYPESLSKLLLITKWNKHEDVVQMVCLLRKWPDLPALHALELLDYSFPDPHVRSFTIRC
LRKLRDDELFQYLLQLVQVLKYESYLDCDLTSFLLERALSNKRIGHFLFWHLRSEMHVSS
VSLRFGLIMEAYCRGSIYHMKSLMKQNEALNKMKALNDFVKSGCQKASRSQTTEEMKVCI
KQDTYLEALSDLLSPLNPSIILSEICADNCKFMDSKMKPLWLMYKNKWMQTDTVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKTESLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRN
NSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYC
EQAYKILCRNGILFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFN
EALRESWKTKVNWMMHSFAKDNR
>K7F3A1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pelodiscus sinensis|TrEMBL
MPPAMADILDIWAVDSQIGADGLISVDFLLPTGTYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVKEFRSKMRRISEEKLLSLVGLSWVDWLNHTYPPEQEPSIPE
NFQDKLYGGNLVVAVHFDKCQDVFSFQVSPNINPVKLNELAIRKRLTIHGKEDEVDPYDY
VLQISGRLEYIFGDHPLIQFQYIRNCVMNRTLPHLTLVECCSIKKMCDQEMIAIEAAINR
KSSNFPLPLPPKKTRTVTLLTQSVWDISYPFKIILFKGNKLNTEETAKVHVRAGLFHGTE
LLCKPIVSAEVFGRSEHIWSETLEFEINVCDLPRMARLCFAIYAIMDKMKTKKSTKTINP
PKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDLLLHSWTSFPDELEEMLNPMGTVQTN
PYTENATALHITFQEYSKFPIYYPPFDKILEKAAEIAKSSENVGMAGRGGKKFYIELKEI
MERDPLTQLCENEMDLIWTLRYDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWSKL
PPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSQFLL
ERALANRRIGQILFWHLRSEVHIPAVSVQFGVILEAYCRGSIAHMKVLSKQVEALNKLKT
LNSLIKLNSIKQSKTKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELYVEKCKYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEEAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A672TDP8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
VGWSASDDEPPVVRREENKRRRRKMKAFTSTSAVLTDQIAVEFVLPTTNKNSKNPDILHL
DVTGNWTIEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVVRQQPTEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDPKLYSMDPWITTKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKN
GEEIHLVLERPPDPEQDVVQKEEWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVNHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERG
QREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEA
VAITHCLLERSTIWDRSSLDVGLALQLLDCHFSDENVRTMAVRKLETLEDDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALGSMRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRG
CGEAMLQDFRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDSF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLCEKCVNEEKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFLGISKERVPFVLTPDFLYVMCTTDKKSSPNFLQFQNVCLKAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQ
FNWFLHLVLGIKQGVEKRSA
>A0A672MF58|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQS
GKSHSGKKILVNVKFEGSEETFVLQQDPQDLPMFLKRNALRKKSNVFRPAKQEKPEDYTL
QVNGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKFQEEQGGLSNQVSRTRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKVKLLILFTCLFIYLHLYID
CPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRF
PNIRPHPLYYPPIEKLNELGMNGEKVVATKEEHLKLREIVDNKNYTEFFEDEKELLWKLR
EEVRQRYPESLPKLLLITKWNKHEDVAQMVGLLRKWQDLPAIHALELLDYSFPDPHVRSF
TIRCLGNLRNDELFQYLLQLVQVLKYESYLDCDLTCFLLERALSNKKIGHFLFWHLRSEM
HVPSVSLRFGLILEAYCRGSIFLIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDM
KVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKDKYDHVGIIFK
NGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQR
NNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFREY
CEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKF
NEALRESWKTKVNWMMHSFAKDNR
>A0A672M1V3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSAELPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKITHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDEYLLEKHPLSQYKYIRSCITLGRLPHLMLVSKDSLYSQLPSS
GFMAPSYSRRTPQPSPCPGGGDPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDEQQIEEHANWSISRELGYSYCLGLSSRLVCDSSISPADAEQLRTLCSRDP
LYEISEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQIYCLLKDWPLMQPESAL
ELLDCNFPDPMVREFALRCLIQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIRDKNKGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFERCFCLF
>A0A672RQ50|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDATGSHSRALYVYPPNVESSSELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEVMI
CFFVVLLCFSSDLQNSRLARDHAMTEADIEQLRQLGNRDPLSEITEQEKDFLWRHRQYCV
NIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCL
EKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKT
VSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQM
RRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEI
IFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQ
IQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAIDLFTRSCAGYCVATFILGIGDRHNS
NIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFE
RFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDY
FMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A672MNK1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQS
GKSHSGKKILVNVKFEGSEETFVLQQDPQDLPMFLKRNALRKKSNVFRPAKQEKPEDYTL
QVNGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKFQEEQGGLSNQVSRTRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKVKLLILFTCLFIYLHLYIV
SWIIFFFYQLFISSLSHDCPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMG
TVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKLNELGMNGEKVVATKEEHLKLREIVDN
KNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVGLLRKWQDLPAI
HALELLDYSFPDPHVRSFTIRCLGNLRNDELFQYLLQLVQVLKYESYLDCDLTCFLLERA
LSNKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSIFLIKSLMKQNEALNKMKALND
FVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMK
PLWLMYKDKYDHVGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNK
TGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAG
YCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHV
IQEGRTNNSEKFERFREYCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDS
LALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSFAKDNR
>A0A834UTL0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Marmota monax|TrEMBL
MLSDPKAYVFTCVNQTAEQQELEDEQQRLCDVRPFLPMLRLVTRQGDRMEKLINSQISLL
IGKGLHEFDCLQDPEVNDFRTKMRQFSEEAPAHRQELGWEAWLQYSFPLQLEPSTRRWGD
SNTSQISNPDLLVNVKFEGSRESFTIQVSTKDVPLALMACALQKKAKVYQHLTMEKPEDY
VLQVNGRHEYLYGSYLLCQFKYICSCLHSGLNPHLTMVHSSSILAMRDEQSKPAPQVQKP
HTKPPPIPMKKPSSVSLWSLGQPFCIELIQGSKINADEQMKLVVQAELFHGNEMLCKTMS
SLEVSMCSEPMWKQHLEFDTNICDLPRMARLCFALYVVMEKAKKARSSKKKSKKVAGTLR
TGVLGEPGDPSLSARPSLAP
>A0A672H486|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salarias fasciatus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQLDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRIKMFRLSEERMQRVQMMTCTEWLQACFSPQLEPP
AATAVTDGVNDRAADLKVIIHFDQSQDSASLKVPSCYTPAELMEQALRKWVTTHGPEEEA
WGGQHVLRVSHCLEFLCGDHPLIQYKYIRSCLQAKEPPHLTLVHTNTVKAMFDKEMTAIG
AVVSRRSSNPPLPLPPKRRVPTVSPETHQVQTCVWDVSSPFKIVLVKGSKVNAEETVQVR
AGLFHGTELLCKPAVSSESSGQRASSEHTWRDNTLEFDISVCDLPRMTRLCFAIYAVMDK
VKKQKSTKNSHINKYQTIRKAGKVHYPIAWVNTMVFDFKGQLKTGDITLHCWSSFPDELE
EMLNPIGTIQTNPYTENATALHIHFPEYSSHPIIFPPFDKVRQTDGRPSRDLARGGKKFY
IELKEIMERDPLSQLCENEKDLIWTLRHDCWENFPQSLPKLLLSVKWSKHEDMAQLQALL
QIWPKLSPRDALELLDFNYPDQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYYDCA
LTHFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEA
LSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPNVQLS
GINVERCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKE
ANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERN
SGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKF
GIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLVLRKNGNLFITLFALMLT
AGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNR
S
>A0A3Q3NEX5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MDRQQIQVSDEEPEIVHEEFRRRRRKKAFTSSSSTSMDQITVEFVLPTAGWAGNSPDTLQ
LEVAGNWTVEQVKGQVWLKAVTMNLSPDFYQRFSPDQCILVYQKKGSVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESQQYQRYLNHLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDSKLYSMDPWVTRKPLPEHLLSKVSNGHILLVIHTGTARQTIKVSIN
DTPVQVLASFFTKTTNKRGLLGIPENMCEADYVLRVCGREEYLYGDQPLQNFNWIRQCLK
NGEEIHLVMEMPPDPDLDLVQKEDWALVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPELIVFIEASIFHGQQLLAQERTISKTFNEEVLWNCWLEFNI
KIRDLPKGARLNLQVVCGKQSQTPNSKGSFYQDNTAGVTSHDGKTKSRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLP
KSRDVGRDVGAAGEESEGGERGQREMPNHLKKQFEAIVATDPLHPLSPEDKELLWHFRHE
CMRDPRAYPKLLGSVRWGKQEDVLITHHLLERSNAWDTSDLDVGLAMQLLDCHYSDAQVR
TMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EISQSMHYQQRYAVLLEAYLRGCGEAMLQDYRKQVDMTEALQKVTREIKAMSADKYDVTA
QVVFQLRQKLETLQISGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPT
TLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETEALDLCLLPYGCISTGNRIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKK
SSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRTE
DEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A2D0T995|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ictalurus punctatus|TrEMBL
MPPAMTDQLDVWADPILDGNDQVAVDFLLPTGIYIQMDVPRESTIHQIKQMLWKQAQVYP
LFSLLGEMDGHIFECVNQAAVHEELEDESRRLCDVRPFLPVLRLIIRNCGRAERLLDSKI
GVLIGKGLHELDALQDQEVKDFRSKMQRISEEKMQSVQMMSWAEWLQSCFSPQIEVAPVD
GLCDRNEGFIKITMHFNQSQDTTSIKVTLSCTVHELMNQALRKWLTTHGLGEDEDCIGNY
VLRVSDKLEFLFGEHQLMYYRYIRSCLLSQESPHLTLVHCDIVKAMFEHEISSIGAVLAR
KSSNPPLPLPPKRRGPSQLHTCIWEVQSLFKITLVKGIKVNAEETAKVQVRAGLFHGTEL
LCKPAVSNESSGRSEHIWNRTLEFDISVCDLPRMARLCFAIYAVMDKVKKQKSTKNMQMN
KYQTIRKAGKVHYPIAWVNMMVFDYRGQLKTGDIILHTWSSFPDELEEMLNPIGTIQTNP
YTENATALHIRLTEYSVNPLTFPPFDKILEKAADIAGSTDSISIGRGLKKFYIELKEIME
RDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHDDMAQLQALLQIWPKISP
RDALELLDFNYPDQYVREYAVSCLQDMSDEELLQYLLQLVQVLRYEPYYDCALSQFLLQR
AQTNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALGKLKAVN
ELIKLGTIKSKNKTKEAQLKEAMMKCLRQTGFIEILSDLHSPLNPQILLADVNVEKCRYM
DSKMKPLWIVYNNKLLLGDTLGIIFKNGDDLRQDMLTLQILRLMDMLWKEANLDLRIVPY
GCLATGDRTGLIEVVSSADTIANIQKNSSNMAAAAAFNKDALLSWLKDKNPGEALEKAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFI
LTHDFIHVIQQGKTGNTEKFGSFRQYCEDAYLILRKNGNLFITLFALMLTSGLPELTSVK
DIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAHPS
>A0A8D0TV23|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKSPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8D1F2Q0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPGVDCPMEFWTKEENQSVDVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKVSQRLALPLPSSPSSSCRRPTREPIGQHSGPGAGPGPLTQAPWLVHVKSR
AFEHPWPTGPVCGGGALRPPLSSQDLLPARLAEFHSLGSSEVSGPSGTCAAGLPVTAGVV
GSTELYRKPAKPPPTPPAMTTGLVTGASLLRIPLLQWPCFSVHLHTQPSSVSLWSLEQPF
CIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSVCSDPVWKQRLEFDINVCD
LPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWP
SVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAPHPVYYPSLDKILELGRHGEHGRF
TEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNRHEDVAQ
MLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYES
YLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLM
KQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDPSILLAE
VCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQ
EGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKN
PGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKF
GINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYAILRRHGLLFLHLFALMRA
AGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNR
Q
>A0A6P8STZ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gymnodraco acuticeps|TrEMBL
MSLWLRWCLLPLAMPPAMTDLLDIWAAHSPLAGHALDHISVDFLLPTGIYIQLDVPREAT
IQHIKLLLWKQAQSFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKL
VTRNCGRAETLLDSKIGVLIGKGLHELDAMNDQEVKDFRSKMFRLSEERMQQVQMMSCNE
WLQACFSPQLEPPAGAAAIAEPVDLKIIIHLDQSQDSASLKVSSSCTPPELIELAVRKWL
TTHGPEEEAWRGQHVLRVSHCLEFLCGQQPLIQYKYIRTCMQAKESPHLTLVHSSTIKVM
FDKEICAIGAVVSRKSSNPPLPLPPKRRVPTQVQTCVWDVATPFKIVLVNGSKVNAEETA
KVQVRAGLFHGTELLCKPAVSSESSGRSDHTWKDSTLEFDLSVCDLPRMTRLCFAIYAVM
DKVKKQKSTKNSHSNKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDE
LEEMLNPIGTIQTNPYTENATALHIHFPEYSSHSIIFPPFDKILEKAAEIAGASDSVPMG
RGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDM
AQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRY
EPYYDCALTHFLLQRAQGNRKIGHFLFWHLRSEIHMPAVCVQFALMLEAYCRGSIPHIEV
LKKQVEALSKLKSVNELIKLGTLKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPL
NPNILLSGINVERCRYMDSKMKPLWIVYNNKLMGGDTLGIIFKNGDDLRQDMLTLQILRL
MDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALL
NWLKERNTGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHIL
GNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFASFRKYCEEAYLVLRKNGNLFIT
LFALMLTAGLPELTSVKDIQYLKDSLALGKTDDDALKQFRQKFDEALRESWTTKVNWMAH
NVAKDNRS
>A0A8D0IJ15|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLDVVKFPD
MSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPLSEITEQEK
DFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPD
PMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFF
WHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQ
KVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDI
MSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLI
EVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVAT
FILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGA
QECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLAL
DKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A6P8PUW2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MPPGVYFPADFWAKEQNKNILIDFLLPTGIYITFSVPRNASLGNIKQSLWHHAQYEPFYH
MLSEPQAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVQKLINSHISLL
IGKGLHDFDSVGDLEVRDFRSKMRQFCEEKAAERQQLGWEAWMEYSFPLQLEPSARLLKM
GIFHINSKNIIVNIKFESSEESFTLQISAKEFPLALVRSALKKKAIVFRQQNKEEPEDYT
LKVNGCSDYIYGQYPLCQFKYISGCLYHNLTPHLTLVPTKSIKELRDEQENLSLQVSKLR
SKPPPPPLPVKKLSPVSLWNFEQAFCVKILQGSNVNADECLKLVVHAGLFHGNEMLCKAV
RTAEVSESSEPIWNQMMEFDIGICDLPRMSRLSFILYAVEKTKKARSTKKKSKKADCPIA
WVNTMVFDWKDMLKTGECCLYMWSSAPDDKGELLNAMGTVQSNPNTESAVALRICFPSIS
QHPVYYPPFEKILELGKAGEQQCSTVDEQQQLKELLERRGSVELYEHEKDMLWKLRHEIR
EQYSEALARLLLITKWNRHEDVAQMLYLLQSWPELPVLFALELLDYNFPDRCVRAFTVNC
LKKLSDEELCRYLLQLVQVLKYESYLDCELTTFLLERALANRKIGHYFFWHLRSEIHVPA
VALRFGLLLEAYCRGSHYHMKVLVKQVEALTKMKALNDIVKISSQKATKPQTKEVMHVCL
KQENYLEALLNLQSPLNPSVILGNVCVDLCTFMDSKMKPLWIMYNNEMNQNHVGIIFKNG
DDLRQDMLTLQMIHLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEIVGNSDTIANIQLNK
SNMVATAAFNKDALLNWLKSKNPGVALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKPNNNEKFERFRNYCE
KAYMVLRLHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFKIKFDE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A6P8Q179|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCIPNGMIVTLECLREATLLGIKHNLFKEARKYPLFH
LLQDESSYIFVGVTQEAEREEFYDETRRLCDLRLFQPILKVIEPVGNREEKILNREIGFA
IGMPICEFEMVKDPEVQEFRRNILSVCKEALDLREASGPHSQALYVYPPNVESTPELPKH
IYNKLDKGLIIVTIWVIVFPNNDKQKYTLKIPHDCLPEQVIADAIRKKTRSMHLSPEQLK
LCVQEYQGKYILKVCGCDEYLLEKYPFSQYKYIRNCITIGRLPHLMLMSKESLYGQLPAN
IFIMPSYARRSVTSCYMNGDVPTKSLWSINSLLRIRILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYLTDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINLFDYKDTLVAGKMALNLWPVPHGLEDLLNPIGVGGSNPNKETPCLELEFSWYT
HAVKFPDTPQIEEHANWSMSRELGLNYCLVGLSNRLARDSSLIENEMEQLRNICNRDPLS
EITEQEKDFLWRHRHYCINIPETLPKLLLSVKWNSRDEVTQMYCLLREWPLIKPELSLEL
LDCNFPDPMVREFALKCLVKGLTDDKLSQYLIQLVQVLKYEQYLDNILARFLIKKALTNQ
RIGHFFFWHLKSEMHSKTVSQRFGLMLEAFCRGCGMYLKHLNRQVEAMEKLINLTDILKQ
EKKDETQKMQMKFLMEQMRRPAYMEALQGFICPLNPVHQLGNLRLEECRIMSSAKRPLWL
NWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIRIMENMWQNQGLDLRMLPYGCLSI
GDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWLKDKNKGEGYDAAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGIQECTKTKEFERRFQEMCYKAYLVIRQQANLFINLFSMMLGSGMPELQSFDDIA
YLRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPLSEAGHD
>A0A341BSP5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neophocaena asiaeorientalis asiaeorientalis|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
AKPPPIPLKKPASVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEEVSWGPWAVGRGPGCSPHRPPTSTCAPQQLQLRE
ILERRGSGELYEHEKDLVWKMRHEIQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPE
LPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFL
LDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLK
ALNDVVKVSSQKTTKPQTKELMQLCLRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMD
SKMKPLWVMYSNEEAGSDGTVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPY
GCLSTGDHTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFI
LTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSK
DIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A341BVN2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neophocaena asiaeorientalis asiaeorientalis|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
AKPPPIPLKKPASVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKQLQLREILERRGSGELYEHEKDLVWKMRHEIQEHFPEALARLLLVTKWNK
HEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQ
VLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTH
HMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMQLCLRQETYLEALSHLQSPLDP
STLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKNGDDLRQDMLTLQMIQLM
DVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLN
WLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLG
NFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHL
FALMRAAGLPELSCSKDIQYLKLPVEKAKPPAFGAKTSGLKLASYFEDGAGRGPPWLGSE
RRALPGEVLGRCPPGSLGAVLLGGSVTCPERVEVQGDGAPC
>L8IQ23|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus|TrEMBL
TMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLH
QLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGF
AIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPK
HIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQL
KLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPM
DCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTG
IYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEH
CPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDW
FXXXXXXVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAIC
TRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKP
EQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLK
KALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINL
TDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSA
KRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLP
YGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAID
LFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFV
LTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQS
FDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3M0IQ61|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hirundo rustica rustica|TrEMBL
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGFGS
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
WEVAVCSEPVWRQRLDFDINICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEMLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIVLAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A852GDT9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Larus smithsonianus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQPFYVELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFRYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K7EEX1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sylvia atricapilla|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEILLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A091G5P1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cuculus canorus|TrEMBL
SRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQNEPL
FHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYSFPLQLEPMAKGF
GTGLLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHQGLTPHLTMVHCSTIIAMRDEQTNCIASPPK
MTAKPPPLPKKRPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYSVVEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTDSAAALVICFPSV
ASHPVYYPSFEQKTLRSSSGLTLSPVYALSCGSHEQKLQLKEILERRSYTELYEHEKDLV
WKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRY
VGSFAINSLKKLTDHELLQYLLQLVQVLKYESYFDCELTKFLLDRALSNRKIGHFLFWHL
RSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKSLNDFVKSSSQKTTKPQT
KEMMHVCMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGRG
GVGVIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSD
TIANIQLNKSNMAATAAFNKDALLNWLKSKNPGAGYCVATYVLGIGDRHSDNIMIRETGQ
LFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMI
LRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRES
WKTKVNWLAHNVSKDNR
>A0A8C4D8Q2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHDLFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMTIIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNEQLRQVCNRDPL
SEITEQEKDFVWRHRQACVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRVLCDMLTLQIIRIME
NIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWL
KDKNKGEMYDQAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHK
KKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINL
FSMMLGSGMPELQSFDDIAYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHT
IRQHAMN
>A0A8D2MGC1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zonotrichia albicollis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRLARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8B9BS92|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anser brachyrhynchus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GLLHTPTKNIFVNVKFQSGGESFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANTPKMS
PKPPPLPKKKPNYSSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPNVAS
HPVYYPSFEQLLELGRNGEPHRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L4K0B7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ceuthmochares aereus|TrEMBL
MPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQNEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYSFPLQLEPMAKGFGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHQGLTPHLTMVHCSTIISMRDEQTNCIASPPKMT
AKPPPLPKKRPNYGSLWSLEQPFYVELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTDSAAALVICFPSVAS
HPVYYPSFEQLLEVGRNGEQPRAAPEDPEEKLQLKEILERRSYTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELLQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKSLNDFVKSSSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGRGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFESRFR
GYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRL
KFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6J2L0G0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phyllostomus discolor|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
SFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKVLCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSTRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVCXQMKFLVEQMRRPDFMDGYQGFLSGPLKSPPAHQXGNLRLEECRIMSSA
KRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLP
YGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAID
LFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKFGYKRERVPFXL
TQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSF
DDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A673W4I1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
LYTLLHLYTLLHLYTLLHLYPLLHLYTLLHLYPLLHLYTLLHLYTLLHLEEFYDETRRLC
DLRLFHPILKVIEPLGNREEKILNREIGFAIGMPICEFEQLKDPEVQDFRRSILSVCREA
LYVYPPNVESAPELPQHIFCKLDKGRLIVTIWVIVSPSNSKQKYTLKISHDSLPEQLIAE
AIRKKTRSMHLSAQQLRLCVQEYQGHQYKVGQRERHTQAHNNEFSHIHVHTHTHTQTTTH
THTHTLFS
>A0A667WCE7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MPPGKYGMQAEWEKEGDHKIMMDFLLPTGIFLKFPVSRNETIKNIKKMVWRNAATEPLFS
ALGDSDAYVFTCINQTAEREELEDESRRISDVLPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHDFEAQKNHEVNEFRSKMRSFCEEKALERQLLPWHQWIEYSFPCELEPCSSLPES
GNTKSKNTKKIFVNIKFEASDESFMLQQDPHDFPVSLMKNALKKKATVFRLVRQEPEDYT
LQVNGRWDFIYGKHPLCQFKYIFSCLRNSQNPHLIMVHSSTINKYQEEQGTMCSQVSKSG
SLSRPPPLPLKKNTSSLWSINEPFYIHLVQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SSEVAVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIR
PHPLYYPPHDKVLNPKHLYLSLKEIMDNKNYTEFFEDEKELLWKLRAEVRDRYPESLSKL
LLITKWNKREDVAQMLSLLRNWPDLPALHALELLDYSFPDPTVRAFTIRCLRKLSDDELL
QYLIQLVQVLKYESYLDCDLTTFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILE
AYCRGNIYHIKVLSKQNEALGKMRALSDFVKTGSQKMTAEDLKLCIRQESYLEALSDLLS
PLNPSIILSEICADKCRFMDSKMKPLWLMYKNQWVQGDMVGIIFKNGDDLRQDMLTLQMI
QLMENLWKKEGLDLSRDKIDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFH
IDFGHILGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCERAYKILCR
NGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFTEALRESWKT
KVNWMMHSLAKDNRP
>A0A667X8G4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
LYSINKKILILILIKPKLLLWKQAQTYPLFPALGEMEGHMFECVNQAAVHEELEDETRRL
CDIRPFLPVLKLVTRNCGRAERLLDSKIGVLIGKGLHELDALQDQEVKDFRSKMFRISEE
KMQRVQKMTWTEWLQACFSPQLENGGGAITDGPALLSPCISVWSFPLLQDTASLKVSPSC
TPTELMELALRKWLTTHGPEDEARRGQYVLRVSQRLEFLCGDHGLIQYKYIRSCTQAKES
PHLTLVHTSTVKAMFEKEISAIGAVVTRRSSNPPLPLPPKRRIPTVSFEICFKIVLVKGS
KVNAEESAKVQVRAGLFHGTELLCKTAVSSESSGRSEHTWSDGTLEFDICVCDLPRMTRL
CFAVYAVMDKVKKQKSTKNTHLNKYQTIRKHYPIAWVNTMVFDYKGQLKTGDIILHSWSS
FPDELEEMLNPIGTIQTNPYTENATALHIHFPEYSSHPIVFPLFDKGRGGKKFHIELKEI
MERDPLSQLCENEKDLIWTLRHDCHENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKL
SPRDALELLDFNYPDQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLL
DRAQSNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKS
VNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEK
CRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDMLWKEASLDLR
IVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALE
RAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRER
VPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPEL
TSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A674AG08|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
IELQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIEGAALWATLCCLPVTNSHILLVIHRNKASQTIKVSIDDTPVQVLQTFFTKI
SNKRALLGVPEDVCEGDYILRVCGREEYIYGNHPVRDFHWVRQCLKNGEEIHLVLESAPN
PGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDCHRKFRVKVLGIDIPA
LPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFNIRIRDLPKGARLSLQ
DNGGSPSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKA
SSMAVAILLDKYCYPVALPKSREGERGQREMPNHLRKQFESIVETDPLHPLSQEDKELLW
HFREECMRHPRAYPKLLGSVRWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYS
DAHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLF
WFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEK
YDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFK
RADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKI
GMIEIVRDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYC
VATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMG
TSGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALT
VGRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGGDKRSA
>A0A673ZDP5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPAMPDDLDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFCPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQACFSPQLEPGGG
ATPLTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSSVQAMFEKEISA
IGAVVNRKSSNPPLPLPPKRRGPSQVNTCVWEVSTQFKIVLIKGSKVNAEESVQVRAGLF
HGTELLCKPVVSSESSGRSEHVWNRTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKSTK
NAHINKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPIGT
IQTNPYTENSTALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCSTMSRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTR
FLLNRAQCNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGIN
VEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGD
ALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGL
PELTSVKDIQYLKVSLSKIMYTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A3Q3DJ44|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hippocampus comes|TrEMBL
MPPAMTDLLDIWADHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATFQHIKLLLWKQAQ
TFPLFPALGEMESHMFECVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCSQAERLLD
SKIGILIGKGLHELDGMNDQEVKDFRSKMSRISEERMQRLQMMTWTEWLRACFSPQLEPR
IINDGLNDRSAHLKVIIHVDQSQDSASVKVPASCNAAELMELAVRKWLTTHGHEEEAWRG
QYVLRVSHCMEFLCGDHALCEYKYIRTCMQAKESPHLTLVSSSTVKAMFEKEICAIGAVI
NRKSSNPPLPLPPKRRIPMQAQTCVWDVPSPFKIVLLKGSKVNAEETAKVQVRAGLFHGT
ELLCKPAVSSESNGRSEHTWKESTLEFEISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNA
HPNKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKMGDIVLHCWSSFPDELEEMLNPIGTIQ
TNPYTENATALHINFLEYSPYPIIFPPFDKILEKAAEIAGASDCAPMGRGGKKFHIELKE
IMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPR
LCPRDALELLDFNYPDQYVREYAVRCLYDMSNEELSQYLLQLVQVLRYEPYYDCALTHFL
LERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALMLEAYCRGSIPHIEVLKKQVEALSKLK
SVNELIKLGTMKNARGKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGMNVE
KCRYMDSKMKPLWIVYNNKLLAGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDL
RIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAATAAFNKDALLNWLKERNSGDAL
DRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRE
RVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPE
LTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A663MMK5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Athene cunicularia|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A663LSK0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Athene cunicularia|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQVSLVSRFINEPPNYGSLWSLEQSFYIELVQGSKVNADERM
KLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIE
KAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTV
QCNPNTESAAALVICFPSVASHPVYYPSFEQVGDVDFFWGARSAEKRRSLSHSLFVSQLL
ELGRNGEQPRQKLQLREILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWN
KHEDVAQVRMLGLATWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQYLLQL
VQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGS
THHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHVCMKQETYLEALSHLQSPL
NPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQL
MDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALL
NWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFL
GNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLH
LFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAH
NVSKDNRQ
>A0A6I9Q4X6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Notothenia coriiceps|TrEMBL
MDGQQTQVSDEEPKVLREEPRRRRRKKAITSSGSSMDQISVEFILPTVVRGGSSPDSLLL
EVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTL
DCIRYWRALKKEVGRIQLLPRPQPSDESLQYQRYLNYLIAYDVTDVSNVHDDELEFTRRK
LLTPRRLELSDRDPKLYSMDPWVTRKVLPERLLNKVSNGKILLVIHIGTASQTIKVSISD
TPAQVLLSFFAKTASKKALLRIPEDTCEADFVLRVCGREEYLYGDKPLQDFNWVRQCLKN
GEEIHLALEDAPDPELDLVQKENWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNR
KFRVKVLGIDIPSLPKVPGLIVFIEASIFHGQQLLAQERTSSKNFNEEVLWNCWLEFNIK
IRDLPKGARLNLQVICGKQPLTPTSKGTLSYQDTAPSTGSHEGKTKSRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASAMAIAILLDKYCYPVVLP
KSRDVCRDGGGGGEEAEGERGQREMPNHLKKQFAAIVNTDPLHPLSPEDKELLWHFRTEC
MRDPRAYPKLLASVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQMLDCHYSDAQVRS
MAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKKALRSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGEEMLQDFRKQVEMTEALQKVTREMKAMYADKYDITTQ
VVFQLRQKLETLQSSISLKSFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTT
LSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIV
KDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVCEDKFQQAVEKFLYSCGGYCVATYVL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKS
SPHFLKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEE
EAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A6J3JMS3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sapajus apella|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLNGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRTKMCQFCEEAAACRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHFSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDISISDLPRMARL
CFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLHMWPSVPDEKG
ELLNPTGTVRSNPNTDSAAALLICLPEVAPYPVYYPPLEKILELGRHSECVRVTEEEQLQ
LREILERRGCGELYEHEKDLLWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCS
WPELPVLGALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELT
KFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALS
KLKALNDFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCT
FMDSKMKPLWIMYSNEEAGSSGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRM
TPYGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDR
AIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERV
PFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELS
CSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L1VV79|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Certhia brachydactyla|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCASSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSQEVQEFQQQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDQVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIGTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C6JZS6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Melopsittacus undulatus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKAYAV
LLVLQESFTFQISPNEFPITLMSYAIKKQATVFRHETVEKPEDYTLQVNGKCEYLYGNYP
LYQFQVSLMSCFVNESVPIAGRKSLLCLFLIGGTLFSSQPNYGSLWSLEQSFYIQLVQGS
KVNADEGMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWQQRLDFDINICDLPRMARLC
FALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGE
LLNPMGTVQCNPNTESAAALVICFPSVASHPVYYPSFEQVRNMFFGGLHTRLQLKEILER
RSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVL
NALELLDFSFPDRYVGSFAVNSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRA
LSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALND
FVKASSLKATKPQTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMK
PLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLST
GDKTGLIEVVMQSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDF
VHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYL
KDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKNNRQ
>A0A8C5J5U9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Junco hyemalis|TrEMBL
MPPGIYCPTEFWSKGENQSIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPNKNIFVNIRFHFMFQISPWEFPITLMSYAIKKQATVLRPETVQQPEDYTLQVNGKC
EYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASKPPPLP
KKKVRGDRDPWAPLAQAVPRAHGAVLAVPQLVVQAGLFHGTEMLCKTVSSSEVSVCSEPV
WRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWANVMLFDYRD
QLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHPVYYPSFDP
ECALAVQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNRHED
VAQMISLLQTWPELPVLNALELLDFSFPDRYVGCVSCFLSVLRDDDVFQYLLQLVQVLKY
ESYLDCELTKFLLERALSNRKIGHFLFWHLRGYLNVFNLSPGISYLLTLFHPSHVQGEAL
NKMKALNDFVKVSSQKATKPQTKEMMHMCMKQETYREALSHLQSPLNPNIILAEVCVDQC
TFMDSKMKPLWIVFNSEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRM
TPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALDQ
AIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRETGQLFHIDFGHFLGNFKTKFGINRERV
PFILTYDFVHVIQQGKTNNNEKFERFRGYCERAYMILRRHGLLFLHLFALMKAAGLPELS
CSKDIQYLKDSLALGKTDEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P5PIV6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus caroli|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPID
SFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A1A6HR53|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neotoma lepida|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
SFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPL
HYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRSFA
VRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEM
HNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFL
VEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQ
NNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRNSHTIMQIQCKGGLKGALQFNSH
TLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFG
HFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHA
NLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKM
DWIFHTIKQHALN
>A0A7R5KEG3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pipra filicauda|TrEMBL
MRPRRGQGPGPGAPGPRRGRGGRGGPTAGSLFARRVIGGGSRAASPAGHGASPPAPGPRC
FLLRRTPVRSRGRGRRCGVMEFDGKAADEAAGTLKQYEANDHTRQWQQFPWVLRSISSGM
ELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMMLLEI
AGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLDC
ILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRLV
TPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKIINNNIFIIIHRGTTSQKIKVSIDDTP
DMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYIIGETPVKDFHWIRQCLKNGE
EIHLVLDDPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRKF
RVKIIGIDIPILPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKIK
DLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDTKCKTQLLYYVNLLLIDHRFLLRSG
EYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRIASDP
QGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVKW
GQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVLH
YLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILE
AYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSSK
LPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDL
RQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGN
TGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETG
NLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDICVKAYL
ALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDK
GWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3Q2CV98|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinodon variegatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLIAIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRNASGPHSRALYVYPPNVESTKELPKH
ISSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTQDQLK
MCVQEYQGKYILKVCGCDEYLLENYPLSQYKYIRSCIMLNRMPNLMLMSKDSLYTQLPTD
NFVMPSYARRISTATSYMNGEASSKLLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEKCL
IGVFFTTPVWVVVVGKNVVFQCVAFVRFQSSRTARDHALTESDSEQMRQLSNRDPLSEIT
EQEKDFLWRHRQYCIHIPAILPKILLAVKWNSRDEVAQMYCLLEELPYIPPEQAMELLDC
NYPDPRVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDSPLARFLLQKALTNQRIG
HFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKK
DETQKVQMKFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLWLNWE
NPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDC
VGLIEVVRNSHTIMKIQCKGGLKGALQFNSNTLHQWLKDNNKGEMYDMAVDLFTRSCAGY
CVATFILGIGDRHNSNIMVKEDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVI
SKGCQEYTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRK
TLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHTLN
>A0A8C7XZB6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias sinensis|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETCYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDFEVQDFRRNILNVCKDAVELRDANGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYSQLPTD
SFVMPSYCRRISTATSYMNGEAAPKSLWTISGGLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLNYDMYILDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYNHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEHF
SSPVKYPDMNAVEEHANWTISRELGFNYNTSGQSNRVARDHALTDSDSEQLKQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKFLADDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNRGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKGEQVSRHFMGNQSLRSFEASPHQLKRLFHVAGSIGLLYETDERCSPWRVD
HQDGLDIPHD
>A0A7L0KRF7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sylvietta virens|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTEAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTPDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CMLYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMQPWTTSKPLPEYLFKKIINNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERIFTVSLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAQTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQGAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C7Z8Y3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias sinensis|TrEMBL
MPPAMTDLVDIWAAHSPLDGQAPVHVTMDFLLPTGIYIQMEVPREATIQHIKLLLWKQAK
SFPLSSFLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVFRLVTRNCGRAERLLD
SKIGVIIGKGLHELDGINDQEVKDFRSKMQRLSEERMHRVQMMSFTEWLQACFSPQLEPS
AGTAIADGANDWPADLKVIIHFDQSQDSTSLKVPSSCTPSVLIEIALKKWQTTHAPEEET
NKDKHILRVSQCLDFLCGDHPLIQYKYIRSCLQAKESPHLTLVHINAVKAIFDKENAAIG
AVVSRKSSNPPLPLPPKKRAPTQVQTCVWDVSRPFKVVLVKGSTVNADENAKVQVRAGLF
HGTELLCKPAVSSESSGRSNHSLENNTLEFEISVCDLPRMTRLCFAIYAIMEKVKKKSYK
NPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDMILHCWSSFPDELEEMLNPIGT
VRINPYPENATALHIHFPDYGPHPIVFPPFDKILEKAAEIAGSSDSTPIGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRLDCRENFPQSLPKLLLSVKWSKHEDMAQVSLLFSYR
IVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALE
RAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRER
VPFILTHDFIHVIQQGKTGYTEKFGRCVPLFHSCGSHVPIQVQDSLALGTTQKPASPVQV
HVTPYRCM
>A0A665UKS5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
HLSDDEPKFQREEIRRRRRKKAITSSSGTSMDQITVEFILPTVARGGNSPDSLQLEVAGN
WTVEQVKAQLWLKAVTSNLCPDFYQRFSPDHCILLYQKKGNLYEIYDKHQVFQTLDCIRY
WRALKKDVGRIQLVPRPQPSDESLHYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPR
RIELSDRDPKLYSMDPWVTRKPLPEHLLSKVSNGHILVVIHIATASQTIKVSIDDTPVLA
SFFTKTANKRVLLGIPENMCETDYVLRVCGREEYLYGDKPLQNFNWIRQCLKNGEEIHLV
LETPPDPNQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTVSMWDCNRKFRVKVL
GIDIPSLPKVPEFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNSWLEFNIKIKDLPKG
ARLNLQVVCGKQPQTPNSKVNSFQDNAGGGKTKSRLLYYVNLLLIDHRSLLRQGEFILHM
WKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVSRDVPAGA
EEAEGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRQECMRDPRAYPKLLS
SVRWGKQEDVLTTHHLLERSSAWDSSGLDVGLAMQMLDCHYSDAQVRSMAVRKLETLEDD
DVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYA
VLLEAYLRGCGEAMLQDYKKQVEMTEALQKVTREMKTMSADKYDVTAQVVFQLRQKLETL
QLSGLPESFRVPYDPGLRAGGLMIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKD
GDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQS
VVGSTGAFKDEILYQWLRDKCISEDKFQQAVERFLFSCGGYCVATYVLGIGDRHNDNIMI
TESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCV
KAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRVEDEAQRHLLDQIEI
CREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A1S3GR37|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dipodomys ordii|TrEMBL
MEFWTKEENQSVMVDFLLPTGVYLNFPVSRNANLSTIKQVLWHHAQYEPFFHMLSDPEAY
VFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVARECDHVKKLINSQISLLIGKGLHEF
DSLRDPEVNDFRDKMRQFCEEAVAHRQQLGWEAWLRYSFPLQLEPLARSLGAGTPKTPNQ
TMLVNVKFEGNEESFTFQVSSKDKPLALMACALRKKAKMFSQCLVEQPEDYALRVNGRHE
YLYGSYPLCQFQYICSCLHSGRTPHLTMVHSSSILTMRDEQSNPTPQVQKPCTKPPPIPA
KKPSLVSLWSLEKAFCIDLIQGSKVNADERMKLVVQAGLFHGNELLCKTVCSSEVSMCSE
PVWQQRLEFEINVCDLPRMTRLCIMLYAVVEKTKKARSTKKKSKKADCPIAWANLMLFDY
KNQLKTGECCLYMWPSVPGEKGELLNPVGTVCSNPNTKSASTLLICLPEVAPHPVYYPAL
EKILELGHHGERAHATEEEQLQLREILERQGSGELYEHEKDLVWKLRHKVQEHFPEALAR
LLLVTKWNKHEDVAQMLYLLRSWPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTDDEL
SQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSVALRFGLIL
EAYCRGCTHHMKMLMKQGEALSKLKALNDFVKVSSQKMTKPQTKELMHLCMRQDTYMEAL
SHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEETGYAGNMGIIFKNGDDLRQDM
LTLQMIQLMDILWKKEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNNSNMAATA
AFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLF
HIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILR
RHGLLFLHLFALMRAAGLPDLSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWK
TKVNWMAHNVSKDNRQ
>A0A665VYF0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TLPLFPALGEMESYMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRLSEERMQRVQKMSFSEWLQACFSPQLEPA
GTTITDGVNEQFSLLVFQDSASLKVSSSCTPTELMEQAVRKWLTTHGPEEEAWRGQYVLR
LSHCLEFLFGDHPLIQYKYIRTCMQAKESPHLTLVHNSTVKAMFDKEMSTIGAVVNRKSS
NPPLPLPPKRRHPTVNKMNKLILQSFLLVQVQVRAGLFHGTELLCKPAVSSESSGRSDHM
WKENTLEFDISVSDLPRMTRLCFAIYAVMDKVKKQKSTKNPHINKYQTIRKAGKVHYPIA
WVNTMVFDYKGQLKTGDINLHCWSSFPDELEEMLNPIGTIQTNPYTENATALYIHFPEYS
SHPVVFPPFDKILEKAAEIARASDCGTMGRGGKKFHIELKEIMERDPLSQLCENEKDLIW
TLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYV
REYAVRCLRDMSNEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGNRKIGHFLFWHLR
SEIHMPAVSIQFALILESYCRSCIPHIEILKKQVEALSKLKSVNELIKLGTTKNARSKTK
EAMLTKEAMMTCLRQSGYSETLSDLHSPLNPHILLSGINVERCRYMDSKMKPLWIVYNNK
LMTGDNLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRAGLIEV
VSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFTLSCAGYCVATY
VLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKT
GYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKT
DDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A665T4X1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKALWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWNISRELGFNYCHTGLSNRLARDNPVTDSDNDQLRQVCNRDPL
SEITEQEKDFLWRHRHDCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A665VYN6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MNLTSVAETCFNSHLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKL
LLWKQAQTLPLFPALGEMESYMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCG
RAERLLDSKIGVLIGKGLHELDAINDQEVKDFRSKMFRLSEERMQRVQKMSFSEWLQAFV
YQNNHFTFKSEEFSLLVFQDSASLKVSSSCTPTELMEQAVRKWLTTHGPEEEAWRGQYVL
RLSHCLEFLFGDHPLIQYKYIRTCMQAKESPHLTLVHNSTVKAMFDKEMSTIGAVVNRKS
SNPPLPLPPKRRHPTTCVWDVSRPFKIVLVNASKVNAEETAKVQVRAGLFHGTELLCKPA
VSSESSGRSDHMWKENTLEFDISVSDLPRMTRLCFAIYAVMDKVKKQKSTKNPHINKYQT
IRKAGKVHYPIAWVNTMVFDYKGQLKTGDINLHCWSSFPDELEEMLNPIGTIQTNPYTEN
ATALYIHFPEYSSHPVVFPPFDKILEKAAEIARASDCGTMGRGGKKFHIELKEIMERDPL
SQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDAL
ELLDFNYPDQYVREYAVRCLRDMRKRFEKMKANEIRFCPPASNEELSQYLLQLVQVLRYE
PYYDCALTHFLLERAQGNRKIGHFLFWHLRSEIHMPAVSIQFALILESYCRSCIPHIEIL
KKQVEALSKLKSVNELIKLGTTKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLN
PHILLVERCRYMDSKMKPLWIVYNNKLMTGDNLGIIFKNGDDLRQDMLTLQILRLMDLLW
KEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKE
RNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKS
KFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALM
LTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKD
NRS
>H2SUG3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
MPPRPSSGELWGMHLMPPSILVECLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDCNGPHSRALYVYPPNVESSPELPRH
IYNKLDKGQIIVVIWVIVSPTNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
IFTIPSYARRISTATPYMNGETATKALWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLSYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEHF
GCPVKYPDMTIIEEHANWNISRELGFNYCHTGLSSRLARDNPVTDADNDQLRQVCTRDPL
SEITEQEKDFLWRHRQDCLNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIRPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A674P803|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
MPPGKYGMQEEWEKEGDQRIVMDFLLPTGIFLKFPVSRNDTIRTIKKMVWKNAQSEALYA
ALGDPDSYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVARVGDRVEKLTNTQISQL
TGKGLHEFEAQKNHEVDEFRAKMRTFCEEKAQERQVLPWLQWMECNFPCELEPCSSPVEC
GGVKSKNTKIFINVKFEASDESFMLQQDPQDLPAALMRAALKKKATVFRSVRQEPEDYTL
QVNGRWEYIYGRHPLSQFKYIFSCLRNSQNPHLTMVHHSTIRKYQEEQGRACSQAYKCHR
PSRPPPLPLKKLVVQAGLFHGSELLCKMVTSTEVAVCSEPVWDQKLEFDINFSDLPRMSR
LCFALYAVIEKNKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDK
GDLLNPMGTVEKNPNVDSAAGLLIQFPNVRPHPLYYPPLEKVPVPAQVRRLRKTKEIMDN
KNYTEIFEDEKELLWKLRSVVCDHYPESLSKLLLITKWNKREDVVQMVGLLRYWSDLPAI
HALELLDYSFPDPAVRAFTIRCLRKLSDEELLQYLIQLVQVLKYESYLDCDLTTFLLERA
LSNSRIGHFLFWHLKSEIHVPSVSLRFSLILEAYCRGNIWHIKLLIKQNEALLKMKTLSD
IVKSGSQKMTVDDLKLCIKQESYLETLSDLLSPLNPSVVLAEICADKCRFMDSKMKPLWL
MYKSPWAQGDMMGIIFKNGDDLRQDMLTLQMIRLMEILWKKEGLDLRMIPYGCLSTGNKM
GLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEGKLEKAIEEFTLSCAGY
CVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVI
QQGRTNNSEKFERFREYCERAYKILCRNGMLFVNLFAMMKAAGLPELTSSKDIQYLKDSL
ALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A452RJX8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus americanus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRQEYLYGGYPLCQFQYICGCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKLVVQAGLFHGNETLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARL
CFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGECCLYMWPSVPDEKG
ELLNPTGTVRSNPNTESAAALVICLPEVAPYPVYYPTLDKVTHPACTSQQLQLREILERR
GSGELYEHEKDLVWKMRHEVQERFPEALARLLLVTKWNKHEDVAQMLYLRAPGPELPVLS
ALEAAGLQLPRPHVASFATSTLRKDDELFRYLLQLVQVLKYESYLDCELAKFLLARALAN
RKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVK
VSSQKTTKPQTKELMHVCMRQETYLEALSNVQSPLDPSTLLAEVCVEQCTFMDSKMKPLW
LVYSSEEAGSDGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGD
RTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCA
GYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVH
VIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKD
SLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C1CG39|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MYIYIYTHTHTHTHTHTHTHIYIYIYTHVHCQNIVMVVCGGFSHMCMRKKASLVLCVKKP
LSFSNLALVMEHQASDDEPPVVRREENKRRRRKMKAFTSSSAVSTDHIAVEFVLPTTNKN
SKYPDTLHLDVTGNWTVEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIY
DKQQVFQTLDCIRYWKALRKEVGKIHLVIRQQPNEDSLQYQRFLNHLIGYDVTDVSNVHD
DELEFTRRKLLTPRKIELSDRDPKLYSMDPWITPKPLPEYLLSKISNNHILVVIHKDTTS
QTIKVSIDDTPVQVLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAISDF
HWIRQCLKNGEEIHLVLEHPPDPELDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVF
TISLWDCNRKFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLW
NTWLEFNIKIKDLPKGARLSLQVSCGKAQTQTSKENECKNKTRLLYYVNLLMVDHRSLLR
QGEFILHMWKMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSP
DSEMEGERGQREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLS
SVKWGKQEAVAITHCLLERSTVWDRSSHDVGLALQLLDCHFSDENVRTLAVRKLETLEDD
DVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYA
VILEAYLRGCGEAMLQDLRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGL
QTSGLPDSFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSRDTIGIIFKD
GDDLRQDMLILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQS
TVGNTGAFKDEILSQWLSEKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMI
TETGNLFHIDFGHILGNYKSFMGISKERVPFVLTPDFLYVMCTTGKKSSPYFLQFQNVCL
KAYLALRHHTNLLIILFSMMLMTGMPQLSSKEDIEYIREALTVGRSEDEAKQHFLDQIEI
CRDKGWTVQFNWFLHLVLGIKQGVEKRSA
>A0A669R8N6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phasianus colchicus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINSIANPPKMA
VKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALLICFPNVAS
HPVYYPSFEQVGNTDQKLQLKEILERRSHTELYEHEKDLVWKMRHDIRDQYPQALAKLLT
ITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQY
LLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAY
CRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQETYLEALSHL
QSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQ
MIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNK
DALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDF
GHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYMILRRHGP
LFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVN
WLAHNVSKDNRQ
>A0A8C1A308|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWVESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQNIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKRISEEKMQCMQLMSWGEWLRSCYSMTLEAGSLE
NLIDKHEGVIKITMHYDQSQDTSSLKVSLHCTVTELMDLALKKWQTTHVPEEDIGFRSDY
VLRVSRKLEFLFEDHHLNQCKYIRDCLLTNESPHLTLVHCDVVKAMFEKEISTIGSVLAW
KTSNPPLPLPPKKRLPTQLHTCVWKVHSLFRIHLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHL
NKYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTN
PYTENATELHISFPEYSTQPVVFPAFDKCLSDMAGRGGKKFYIELKEIMERDPLSQLCEN
EKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFN
YPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHF
LFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVQHFHWSNLSLLGQLLVTKFL
YVKGNSVKNNKNKCLTWTHCISKEEQYLKYKAC
>A0A670J8S5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podarcis muralis|TrEMBL
MPPGIACPVEFWSKEANQSIQVDFLLPTGIYLTLSISCNASLNTIKQMVWHHAQFEPLFH
MLSGPESYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDALSDPEVNDFRTKMHQFCEERVTRRQQLSWKAWMEYSFPVQLEPSFNPQHL
QVGLDSLAASCVLLIIFPSLQESFTFQISPKEFPVTLMSYAVKKQATIFRHQRMNSPEEY
ALQVNGKCEYLYGNYPLYQFQYIRDCLHRGLLPHLTMVHSTSIMALWEEQTNGITHPSKA
SPKPPPVPKKKVSCVGWLCSPLSFISLSQLVVQAGLYHGHEMLCKMVSSSEVNVCSEPVW
GQRLEFEINVCDLPRMARLCLALYAVVEKAKKGSLHWPGSTPRNKTRWYQLKTGECCLPM
WSSFPDEKGELLNPTGTVRTNPNTESAAALVIRFPGILLYPVYYPSFEQVRRWWFAPLSL
ARGKNQYQQLKEILERRSHTELYEHEKDLVWKMRHQVRDQYPGALAKLLVVTKWNKHEDV
AQMIHLLQSWPELPVLNALELLDFNFPDRYVGSFTVNSLKKLTDAELFQYLLQLVQVLKY
ESYLDCKLTTFLLDRALSNRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKS
LMRQSEALNKMKALNGIVKLSALKNPKPQTKEFMHTCLRQETYLEALSNLQSPLNPSVIL
AKVSVELCTFMDSKMKPLWIVFNNEEIGGTSNVGIIFKNGDDLRQDMLTLQMIQLMDILW
KKEGLDLRMTPYGCLSTGDKTGLIEVVMDSDTIANIQLNKSNMAATAAFNKDALLNWLKS
KNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKT
KFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFREYCERAYMILRCHGLLFLHLFALM
KAAGLPELSCSKDIQYLKDSLALGKTDEEARKHFQLKFNEALRESWKTKVNWLAHNVSKD
NRQ
>A0A2F0BKP5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eschrichtius robustus|TrEMBL
VAEGMELESHEQHVVLREDNHRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRNTKTPET
ALLHVAGHGNVEQMKAQVWLRALETSVAADFYHRLSPDHFLLLYQKKGQWYEIYDKYQVV
QTLDCLRYWKVLHRSPGQIHVVQRLAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFT
RRRLVTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNYIFIVIHRSTTSQTIKVS
ADDTPGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQC
LKNGEEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWD
CDRKFRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEF
SIKIKDLPKGALLNLQIYCGKAPALSGKASAEAPAPESRGKAQLLYYVNLLLIDHRFLLR
HGEYVLHMWQLSGKAEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTP
DPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSV
KWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDV
LHYLLQLVQSNISYLDGTLKAPLFRQVWYCVSTPLHMPFPGVQRD
>A0A485PCT9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lynx pardinus|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINICDLPRMARLCFAIYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7J7WM98|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pipistrellus kuhlii|TrEMBL
MELESSHEQPPPVVLREDNRCRRRRMKPRGSSAASLSSMELIPIEFVLPTSQRSSASSSG
GGSGKAPETALLHVAGHGNVEQMKAQVWLRALETSSAADFYQRLGPDHFQLLYQKKGQWY
EIYDRHQVVQTLDCLRYWQALRRSPGQIHVVQRRCPSEDTLAFQRQLTALMGYDVTDVSN
VHDDELEFTRRRLVTPRLAEVAGRDPQLYAMHPWVTSKPLPEYLLRKIAPNHCIFIVLHR
GTTSQTVKVSADDTPGAVLRGFFAKMAKKKSLMDIPESQSERDFVLRVCGRDEYLVGETP
LKNFQWVRHCLKHGEEIHLVLDTPPDPARDAVRKEEWPLVDDCTGVTGYHEQLTIHGKDH
ESVFTVSLWDCDRKFRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTE
EVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSGKASAETPESKGKAQLLYYVNLLL
IDHRFLLRHGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKDSSMSICILLDNYCHPIA
LPKHRPSSDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKA
YPKLFSSVKWGQQEMVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKL
ESLEDDDVLNYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRH
YQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLK
QKLENLQNLNLPKSFRVPYDPGLIAGALVVEKCKVMASKKKPLWLEFKCADPTALSNETI
GIIFKHGDDLRQDMLILQILRIMESIWEIESLDLCLLPYGCISTGDKIGMIEIVKDATTI
AKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRH
NDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQK
FQDVCAKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYF
LDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A091P438|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Haliaeetus albicilla|TrEMBL
SRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVRDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGL
GTGPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGQTPHLTMVHSSTIIAMRDEQTNCIASPPK
MAAKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
AFHPVYYPSFEQGFSGLNKSSGLRLSPVYALSCDSHEQKLQLKEILERRSHTELYEHEKD
LVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPD
RYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFW
HLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKP
QTKEMMHMCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETG
GGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMH
SDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLG
IGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNN
EKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALSKTDEE
ALKHFRLKFNEALRESWKTKVNWLAHNVSKDNR
>A0A7K7NJY1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Haliaeetus albicilla|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLPSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIESLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
RLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A668TM27|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDSEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRYPLSQQIWHYSGLLRTLFRANMYCLLKEWPSIRPEQAMELLDCNY
PDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHF
FFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDE
TQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLWLNWENP
DIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVG
LIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRSCAGYCV
ATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISK
GSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTL
ALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A2K5K6F9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Colobus angolensis palliatus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDGPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSHPLCQFQVRPLRPPCLPGPQPSSVSLWSLEQPFCIELIQGSKVNADE
RMKLVVQAGLFHGNEMLCKTVSSTEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAV
IEKAKKARSTKKKCKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTG
TVHSNPNTDSAAALLICLPEVAPHPVYYPALEKLLGGMLWACRGWRPELLWMCLHARDSA
PSRMIGEMIGVVTPWLGVLPGLVQAPGDAECNRLLQILELGRHSECVHVTEEEQLQLREI
LERRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPEL
PVLSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLL
DRALANRKIGHFLFWHLRYSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLK
ALNDFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMD
SKMKPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPY
GCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFI
LTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSK
DIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C9X1X7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
QYFLNMLLSKLVNLIVLCAFDSSWSFDATIREGATAFLLGIHIQLSAEADLLLNVNVPAL
FSALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMGVLRLVAREGDRVEKLTNTQIS
LLIGKGLHEFEAQKNHEVNEFRAKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPP
ECGSVKSKNTKKIFINVKFEACDVSLSAVVDPQDFPVALMKSALKKKATVFRSVRQEPED
YTLQVNGRWEFIYGNHPMCQFKVSDRSRLKPVFLYDTFLYFEQGRMCSQGYKTRSLSRPP
PLPLKKVRVQRQLSSFINRAAPLSLSPHHSCSSTRLRTLLVVQAGLFHGSELLCKVVTTS
EVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKAVSLSKTS
ADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLI
RFPNIRPHPLYYPPLDKVRILKRLFFMSTNLQRGKTFYISHFTSLTQLKFFEDEKDLLWK
LRTEVRDHYHESLSKLLLITKWNRREDAVQMMSLLRTWRDLPAIHALELLDYSFPDPVVR
SFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLRS
EIHVASVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDFVKSGSQKMTADDLKL
CIRQESYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPIWLMYNPCTQEDMVGIIFK
NGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQR
NSSNSAATAAFNKDALLNWLKSKNPEDKLDRAIEEFTLSCAGYCVATYVLGIGDRHNDNI
MIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREY
CERAYKILCRNGMLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKF
NEALRESWKTKVNWMMHSLAKDNRP
>A0A6J2PIM8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cottoperca gobio|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNIESTQELPKH
FYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTG
IYHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEH
CPLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDH
FSSLVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRSARDHALTESDTEQMRQLSNRDP
LSEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSTRPEQAM
ELLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDIL
KQEKKDETQKVQMRFLVDQMKRPDYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>B0EKX1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Entamoeba dispar (strain ATCC PRA-260 / SAW760)|TrEMBL
MFTYPYCTTPQYSFQPIYSTQNQQSIPMYLPQQNNFIYFQDIPSYQQSYQQPNQPIQQTQ
QTQSINNQIKPNEVVISSDFFQSPQHLKETNQPHSNTLFIPSLMESSVDDFAYFEEQSVI
KPFKDHTYTPSISTVCRYVLTPSDKEYAPKYSYSSDELYVRVLVDYSIHLKNKYPYPVQR
AIMKTSSQGEKICIDRILKIDNDVIHNNFLSFIVSFNKVSYNEAACGVIPVGPNKIKIKV
SVTLTIKDIFRLLEIKDVNAVIAIEDSSTLFCMDDRLIESEYLYDCITHNRIPQFTIIPF
SYCFYKPLPLNKFGNIVNYSNEEFPVCALIKKPFIFNINTVYYNTHVTDEIRVKCVLRCG
DQTLSCPIEKVSFKPIIVTRPLSSNDEKYIYKFSIDEEVDSNLRICDIPLDCEIILFVFI
GQKSIGCASVKVFNAWGVLKRGVQLVHLEEGRRPIGNGIVSGPIVEIDFGSIRAAYHIEG
VEDSKLMNIQKELDTFDSVKNREEFEMMVKMDELKVHEEEIANPVKKMVIDGVDIFQVLR
SPSFITRSPPDYIKSVLIEQMENIPAEFIGQIAHSIDWTDHLQVARFVKYLWTQQIKPLD
ALMLLGYRCPYRAVRAYCISVLDKQPDNVLQFYAIHLSEALRYEEGLTPLTDFLLRRSIA
SPATVGYSLFKMIVGDNSMTKRSIQHSRFIEALLSADPVFASQMTKECEFALNIQTINST
LIRMDSEKRQICRSALLKSISVAVPIPFKPGVIGGLSCEKSKVYTSNAVPLLIDFSGYKM
IFKLGDDLRQDCLILRAFKLFDNLWRMNGLDWRITPFRVISTGNTAGYIEFVRDSRSIGS
IHNDSKIPGVYKVTAIYDWIKNNKTAPLGQCIENFYRSCVGYCVASYVLGLADRHNDNLM
VDKSGHFLHIDFAHFLGNKLKVAGVINREPAPFVLTESMIYVFAGERGTPKYKLKYQEFC
EDCVRAYHVLRQNASLIVSFFTNMISSKLSQLNEIKDAEYLFTSLQLGKQDSLSDLEFVK
LIHDSLNSEQTNMNFFIHSLVQKTKK
>A0A4W3H5L0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPGMQYHQDLWSEDENPDVEVEFLLPTGIYLNFYVPRSSTISYIKKLLWQQAQQQPLFH
TLNEPDAYVFTCINHTAEREELEDERRRLCDVRPFLPVLKLVAREGDRAEKLINSQISLL
IGKGLHEFDCMQDYEVAEFRLKMRQFCEDKESERLRMSWQDWMEYSFPRELEPIQEAPDN
NMIRTLSNRNIVINVKFQYNEESFSFQISPQSHPGTLMQMAVKKKATVFRHKTVEHTEDY
TLQVNGTEEYIYGNYPLGQFKHIWNCMYSSSTPHLTMVHSSTINSLKGEQSNSIAQVPKS
RTYSKPPPLPIKKVIIARCFISWCCWCQRGSVGTAEGLRERLVVQAGLFHGSEMLCKTVS
SHEVSVCSEPAWDQALEFDIHFSDLPRMTRLCFALYGVIDKAKKARSTKKKSKKADCPIA
WVNTMVFDYKDQLKTGDVWLHMWPSIPDEKGELLNPMGTVQGNPNTDSAAALYVRFRNMG
SYPIYYPSFDKVCTELIPRGLLCLDGQQQLKEIMERKSCTEFFEDEKDLVWKLRWESRDH
YSDALAKLLSITKWNKHEDVAQMIYLLQSWPELPALHALELLDYSYPERYVRSFAINCLK
NLRYEELFQYLLQLVQVLKYEPYLDSELTKFLLNRALANKKIGHFLFWHLRSEMHVPAVS
LRFGLILEAYCRGNNYHMKSLMKQCESLKKMKALNDFVKSSSQKTTKPKTKEALHLFMRQ
EAYMEALSNLHSSLNPSSLLTDLWVDKCKFMDSKMKPLWIVYKNEKYDGDPMGVMFKNGD
DLRQDMLTIQMIQLMDVLWKRQGLDYRMIPYACLSTGDKTGLIEVVSRSETIANIQLNKS
NMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIR
ENGQLFHIDFGHFLGNFKSKFGINRERVPFILTHDFVHVIQQGKTSNSEKFERFRKYCEH
AYMILRKHCPLFINLFALMRAAGLPELSSSKDIQYLKDSLALGKTEEEALKHFKMKFDEA
LRESWKTKVNWMAHNVAKDNRS
>A0A7J6BSD2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Onychostoma macrolepis|TrEMBL
MPPGVYGMQDVWEREGRQHINIEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQERQMLPWEPWMKFNFPWDLEPCSVVAQS
GKSRSVKKILVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSNVFRSTKQEKPEDYTL
QVNGTWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRTRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELCTNGEKVVATKEEHLKLKEIVDNKNYTEFFEDEKELLWKLREEVRQ
RYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPALHALELLDYSFPDPHVRSFTIRCL
RKLCDDELFQYLLQLVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRSEMHVPSV
SLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSASQKATRIQTTEDMKVCIK
QDTYMEALSDVFSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDHVGIIFKNGDDL
RQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNS
AATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRET
GQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAY
KILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKELNQQRRVYALESLQRCRLSGCDPGTGRLLIHNTALRYNKNDIILDQESSASGA
GGMNREEAPGKSPEEMYIQQKVRVLLMLKKMGSNLTPNEEAFLRNYAGVVHSQMSQLPQH
PIDQGAEDVVMAFSRSETEDRRQ
>A0A7J6D7C2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Onychostoma macrolepis|TrEMBL
MGAAAESVMRDQMVRGGETRFSFTRPPSGSLALRLLNALVMEHQASDDEPPVVRREENKR
RRRKMKAFTSTSAVSTDNIAVEFVLPTTNKNSRNPDTLHIDVTGNWTVEQVKVQIWHRAV
TTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTLDCIKYWKALRKEVGKIHLVV
RTQPIEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRKLLTPRKIELSDRDPKLYSMD
PWMTSKPLPEYLMSKISNNHILVVIHKDTTSQTIKVSIDDTPVQVLQSFFAKITKKRAIL
GISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKNGEEIHLVLEHPPDPEQDVVQ
KEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRKFRVKILGIDIPVLPRNSEL
IVFVEASIFHGQQLLAQERTISKPFTEEVLWNTWLEFNIKIKDLPKGARLSLQVSCGKAQ
TQTSKENECKNKSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPEKSEDNSSVNADKLTSA
TNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERGQREMPNHLRKQFEQIIATDP
LHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEAVMITHCLLERSTIWDRSSLD
VGLALQLLDCHFSDENVRTMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALARFLLK
RALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGEAMLQDFRKQVEMTEALQ
KVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTLGLPDSFRVPYDPGLRAGALVIEQCKV
MASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDMLILQILLIMESIWELESLDLS
LLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDEILSQWLCEKCVNEDKHQQ
AVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFMGISKERV
PFVLTPDFLYVMSTTGKKSSPHFLQFQNVCLKAYLALRHHTNLLIILFSMMLMTGMPQLT
SKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQFNWFLHLVLGIKQGVEKRSA
>A0A7K8YK30|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sakesphorus luctuosus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQHEPMFQ
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVRKIINSQISLL
IGKGLHEFDSIQDPEVNDFRTKMCQFCEERAARRQQLGWAQWMEYNFPLQLEPMAKGFGP
GSLQTPTKNIFVNVKFQAGGESFTFQISPREFPLTLMSYAIKKQATVFRHETVQRAEDYT
LQVNGKCEYLYGNYPLFQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTLCIATPPKAA
PKPPPLPKKKPNYGSLWSLDQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVSDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLVVTKWNKHEDVAQMIFLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSIHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKELMHM
CMKQETYREALSHLQSPLNPNTILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMLRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K6RKZ4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhynochetos jubatus|TrEMBL
MELGDYDQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEIACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDTKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPSSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A091EED9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Corvus brachyrhynchos|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPIKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINELQSFDDIAYIRKTLALDKT
EQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A1S3QYV3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo salar|TrEMBL
MPPRPSSGELWGMHLMPPSIQVDCLLPNGMILTLVCTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANCNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCGTIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A7L4DUB7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eurystomus gularis|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWTAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQNNCIASPPKMT
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAAEDPEEKLQLKEILERRTHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6I8RCH0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus tropicalis|TrEMBL
MPPIMDHMDIWTADTPLPPDICVDVLLPTGIYVQMDVPRDASISHIKQLLWKHAQSYPLF
HLLLEIDSYMFQCVNHNAVHEELEDETQRLCDVRPFLPVLKLVSRSCNPAEKLDSKIGVL
IGKGLQEFDALKDNEVMEFRSKMRSISEAKIQSLLGLTWVEWLKRTFPPELEPSIQDNIQ
GKLYGGNIVVAIHFENCQDVFSFQVSPNMVPVKVNELAIRKRLTIHGREAEEVDPEDFVL
QVNGRLEFVFGDHPLIQFQYIRNCVMNKALPHLTLVECCNIKKLFDQEMSEIEHAVRRKS
SMHPALPMPLPPKKRGASMKTLNMRDIVWNIVQPYKIILSKGSRLNTEDSVLVRAGLFHG
TELLCKPTMTPEVQGKNDHVWNETLEFEINVCDLPRMARLCFAIYAVLDKPRNKNKTKYQ
TIKKSGKMHFPVAWVNTMVFDYKGQLRSGDHVLHCWSSFPDELEEMLNPMGTVRTNPYTE
NTTTLHIKFHDYSKEPISYPPFDKILEKAAEIARNSDSLSTSGRGGKKLNIELKEIMERD
PLCQLCENEKDLIWTLRYDCRENFPGSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPRD
ALELLDFNYPDQYVREYAVNCLKPMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLQRAL
DNRRIGQFLFWHLRSEVHNPAVSVQFGLLLEAYCRGSVAHMKVLSRQVEALNKLRTLNGL
IKLNAVKLSKVKNKDNMHTCLRENAYKEALMHIQSPLNPSITLSELVVEKCKYMDSKMKP
LWIVYNNRGFGSDSLGIIFKNGDDLRQDMLALQLLRLMDMLWKEAGLDLRIVPYGCLATG
DRCGFIEVVSAAETIADIQLDSSNLAAAAAFNKDALLNWIKECHSGDDLERAIEEFTLSC
AGYCVATYVLGIGDRHNDNIMVRKTGQLFHIDFGHILGNFKSKFKIKRERGPFILTYDFI
HVIQQGKPGNTEKFGRFRQCCEDAYLILRRNGNLIITLFALMLTAGLPELSSVKDIQYVK
DSLALGKKEEDALKQFRQKFDEALKESWTTKVNWMAHTMRKDYKA
>A0A8C3NL21|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geospiza parvula|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQVWMRAIETSQTTDFYHSFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSSSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>F7DUD6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ornithorhynchus anatinus|TrEMBL
MPPRPSSGELWGIHLMPPRIIVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLMYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMTVIEEHANWTVSRELGFNYSHAGLSNRIARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPRVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A851W662|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Corvus moneduloides|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTVDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHDSSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAVSIVLDRYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKLVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A5E4C9N6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Marmota monax|TrEMBL
MRLEPRNLEEPRAFLLWNSHTSNFLNVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVG
NREEKILNREIGFVIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYV
YPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIR
KKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLM
LMAKESLYSQLPMDCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNV
NIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSI
CSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNP
NKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELREN
DKEQLRAICTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCL
VKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLD
NLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQV
EAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRL
EECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQN
QGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNK
GEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFG
YKRERVPFVLTQDFLIVISKGAQECTKTREFER
>A0A3Q2WG94|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Haplochromis burtoni|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVMRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRSKMFRISEERMQQIQMMAFSEWVQACYSPQLEPA
AVTAITAGVNDAPVDLKVIIHFDQSQDSASLKVSLSCTPNELMEQALKKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKEAPHLTLVHTSTVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRRAPTQVQTCVWDVPKPFRIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSNESSGRSEHTWKDNTVEFEISVCDLPRMTRLCFAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHPIVFPPFDKILEKAAEMVSADCVSIGRGVKKFYMEL
KEIMERDPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVRCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTH
FLLERAQRNRQIGHFLFWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRIVPYGCLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSNGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKVRQSQVAMQGEHKNCSSVTVCMYRYGVVVVECTNISVFYKD
>A0A8C8J8R8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRVKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQLSKS
RSLSKPPPLPVKKLVVQAGLFHGSELLCKVVTSGEVNVCSEPLWDQKLVFDISVSDLPRM
SRLCFALYAVIEKAKKPRSTKKKNKKADCPLAWVNTMVFDYKDQLKTGEFLLSTWPSVPD
DKGDLLNPMGTVEKNPNVDSAAGLLIHFPNIRPHPLYYPHFDKPTSYICNHYTCNHLLKE
IVDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKLLLITKWNKHEDVAQMVTFLQKWPD
LPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFL
LERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGNIYHIKSLWKQNEALNKMK
ALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLLSPLNPSIMLSEICADRCKFMD
SKMKPLWLMYKNKWVQGDTVGIIFKNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYG
CLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEE
FTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFIL
TYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKD
IQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDSRL
>A0A8D2C921|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIDML
QKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLPQSFRVPYDPGLKAGALVIEKCK
VMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDL
CLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLSHWLKEKCPIEEKFQ
AAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKER
VPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQL
TSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A6P8S8J2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MELETYEQPVVLREENKRRRRRMRPHSAAHNLSSMELISIEFFLPTFSKLTKTQDTLVLE
IAGNCTVEQMKAQVWMRAIETNLNSDFYHKLTPDHFLLHYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKSVGKIHIVEKQKMTDEVVEFQKQLNYLIGYDVTDVSNVHDDELEFTRRRL
VTPRVIELASRDPRLYSMDPWITSKPLPEYLFKKIASSNIFIVIHRGTTSQTIKVSIDDT
PNMILQTFFTKIAKKKSLLDIPEDHSELDFVLRVCGRDEYIIGDTPIRDFHWIRECHKNG
EEIHLVLDIPPDPALDEVQKEEWPLVDDCTGVTGYHEQLTIEGKDHEKVFTISLWDCNRK
FRVKVIGIDIPVLPRNTELMVFVEANIQHGQQLLAQKRTTCKPFTEEVLWNTWLDFDIKI
KDLPKGALLNLQIYCGKSPSLTTKTNVQPHDTLSSDSKCKNQLLYYVNLLLIDHRFLLRQ
GDYVLHMWKIPGKGEEQGSINADKLTSATNPDKETSMAISIVLDRYCHPIALPKHRTVSD
LEADRTRTEMPNQLRKQLEEIIATDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLASVK
WGHQETVAKTYQLLAKKEAWDRSSLDVGLTMQLLDCNFPDENVRAMAVQKLESLQDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRFAVLL
EAYLRGCGKAKLHDFMKQVQVTEMLHKVTMEIKSISAEKYDITSQVITQLRQKLDKMQNS
KFPESFRVPYDPGLRAGTLVVEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEVLNQWLKEKCPVEEKFLASVERFVYSCAGYCVATYVLGIGDRHNDNIMITES
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSQHFHKFEDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGRSEDDAKRHFLDQIEICRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>E7F251|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Danio rerio|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERLLDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKRISEEKMQQMQMMSWGQWLRSSYSPQLDTSSLD
NLIERHEGIIKITMHYDQSQDTASLKVSLNCTVSEVMDHALKKWQTTHGPEEDIGARSNY
VLRVSDRLEFLFEDYPLIQYKYIRACLSTGENPHLTVVHFDIVKSMFEKEIATVGSVLAR
KTSNPPLPLPPKKRQTTVRTSSMSASQLPQQLHTCVWKVHSLFRINLVKANKVNAEDAAK
IQVRAGLFHGTELLCKTAVSNESSSRSEHVWNKTLEFDIPVCDLPRMARLCFAIYAVMDK
VKKQRSTKNTHLNKYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELE
EMLNPIGTIQTNPYTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMSMGRG
GKKFYIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQ
LQALLQIWPKLSPRDALELLDFNYPDQYVREFAVSCLKDMSDDELLQYLLQLVQVLRYEP
YYDCSLSRFLLERAQTSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLK
KQVEALNKLKAVNELIKLGTIKTKTKQAHLKEAMMSCLRQTGFIETLSDLHSPLNPNILL
AGVSVEKCKYMDSKMKPLWIVYNNKLLGGETVGIIFKNGDDLRQDMLTLQILKLMDLLWK
EANLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDK
NSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSK
FGIKRERVPFILTHDFIHVIQEGKTGNTEKFGNFRQYCEEAYMILRKNGNLFITLFALML
TAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>F1QAD7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Danio rerio|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGAHSRALYVYPPNVESSPELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMD
NFTMPSYSRRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRVARDHAMTEADIEQLRQLGNRDPL
SEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSTTLHQWLKDKNKGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A2J8US96|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pongo abelii|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNP
TGTVRSNPNMDSAAALLICLPEVAPHPVYYPALEKLLGGMLLASRGWRPELLWMCLHAQD
SAPSRTIGVAMPCLGVLPRLVQAPGDAECSCLLQILELGRHSECVHVTEEEQLQLREILE
RRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPV
LSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDR
ALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A1A8ECH8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius kadleci|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREAALNTIKHELFKEVRKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDSSGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYTQLPTD
SFVMPSYSRRISTATSYMNGEAASKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSVCSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVASKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNFPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSPECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8B8YCH2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balaenoptera musculus|TrEMBL
MELESHEQHVVLREDNRRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLSPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRLAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNYIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAEAPAPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKAEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEEAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A671T135|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPAKTDQLDLWAESGLDGDVQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSCGEWLRSCYSTQLGTGSLE
NLIDKHEGDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDYVLRVSGRFEFLF
EDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLARKTSNPPLPLPPK
KRPPTVSTLSVFPALQLIKGVPSFVHLAVRAGLFHGTELLCKTAVSSESSSRSEHVWNKT
LEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIPWVNTMVFDYRGQLKT
GDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVFPAFDKFLSS
VEHKECVLKNVENQTVLKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVK
WSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVICLRDMSDDELLQYLLQ
LVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRG
CIPHIEVLKKQVEALNKLKAVSELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLQ
SPLNPNILLAGVHVERCKYMDSKMKPLWIVYNNKLLGGDTVGIIFKNGDDLRQDMLTLQI
LRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKD
ALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFG
HILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNL
FITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNW
MAHIVAHPS
>A0A7L4EZE5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hirundo rustica|TrEMBL
DSIMPPAVADSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQA
HSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHVRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7L2C232|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alaudala cheleensis|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLDTIKQVLWKQAQHEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRARKVLNSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETLQKPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCISSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVAVCSEPVWRQRLDFDISICDLPRMARLCLALYAVIEKARKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLREILERRSHTELYEHEKDLVWKMRHE
IRDQHPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQRATKPHTKEMMHM
CMRQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3L8S5Q8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chloebia gouldiae|TrEMBL
MPPAVTDNLDIWAVDSQIASDGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDISNPFKITLLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKVKTKKSTRAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHAGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6P6MHH1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carassius auratus|TrEMBL
MEHQASDEEPPVVRREENKRRRRKMKAFTSNSAVSTDQIAVEFVLPTTNKNSRNPDTLQI
DVTGNWTVEQVKVQIWHRAVTTKLCPEFYQKYSPDNCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVVRTQPSEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDPKLYSMDPWMTTKPLPEYLMSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFAKISKKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKN
GEEIHLVLEHPPNPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLLVDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKDNSMAVAILLDKYCYPVALPKSKDSPDSEKEGERG
QREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEA
VMITHHLIERCTVWDRSSLDVGLALQLLDCHFSDENVRTLAVRKLETLEDDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALRSQRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRG
CGEAMLQDFRKQVEITEALQKVTREIKQMSAEKYDVSAQVVLQLRQKLEVLQTSGLPDSF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITESGNLFHI
DFGHILGNYKSFMGISKERVPFVLTPDFLYVMSTTGKKNSPHFLQFQNVCLKAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEEEAKQHFLDQIEICRDKGWTVQ
FNWFLHLVLGIKQGVEKRSA
>A0A672U5V2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVHDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAVN
RKSSNLPLPLPPKKTRTTTNSIGSVASLKFLITLLQVHVRAGLFHGTELLCKTIVSTEIS
GRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKHYPVAWVNTMVFDYKG
QLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIRFQEYAKQPINYPPFDK
VRVAEHWNRLPRAVGRGGKKFYVVLKEIMERDPLSQLCENEMDLIWTLRYDCRENFPQSL
PKLLLSLKWNKLEDVAQLQALLQIWPKLLPREALELLDFNYPDQYVREYAVGCLKQMSDE
ELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQMLFWHLRSEVHIPAVSVQFGL
ILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAMKQSKAKGKDAMQTCLKQNAYRE
ALSDLQSPLNPSVILSELHVEKCRYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQD
MLTLQILRLMDILWKEAGLDLRILPYGCLATGDHSGLIEAVSSSETIADIQLNSSNVAAA
AAFNKDALLNWLKEYNLGDDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQL
FHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLIL
RKHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESW
TTKVNWMAHTVRKDYRS
>A0A672US85|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
VYAVLLGLQESFTFQISPNEFPITLMSYAIKKQATVFRHETLEKPEDYTLQVNGKCEYLY
GNYPLYQFQVSLVSSFSNESVPIAGRSSPRGFMAFSSFSFPQLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQVGTFPTLSYDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQ
YPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAVNSLK
KLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVA
LRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMMHVCMKQ
ETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGD
DLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKS
NMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIR
ETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEK
AYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEA
LRESWKTKVNWLAHNVSKNNRQ
>G3UQL7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Meleagris gallopavo|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQVNSIANPPKMA
VKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNVAS
HPVYYPSFEQLLELGRNGEQPRSQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYP
QALAKLLTITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKL
TDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALR
FGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQET
YLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDGK
SLRICFLGMIVSRFQQKGFFRLCRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMA
ATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETG
QLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYM
ILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRE
SWKTKVNWLAHNVSKDNRQ
>A0A5F8AGD6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca mulatta|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKSRGGKKFLPVLKEILDRDPLSQLCENEMDL
IWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQ
YVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWH
LRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNRAK
GKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGE
DSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTS
ETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGI
GDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTE
KFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEA
LKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8I3VYH1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callithrix jacchus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFESTQGECFQLFPIQYDIGLGFVI
>A0A4U1EGU0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodon monoceros|TrEMBL
MADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNYPMFN
LLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKIGVLI
GRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKQTYPPEHEPSIPENLED
KLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKDDEVSPYDYVLQV
SGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAIEAAINRNSSN
LPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKDYPVAWVNTMVFDFKGQLRS
GDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIRFPENKKQPYYYPPFDKIIEK
AAEIASSDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLP
KLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLQQMSDEE
LSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLSIEKCKYMDSKMKPLW
LVYNNKVFGEDSVGVIFKNGD
>G7MGT3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca mulatta|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKVLLAMGPGALGMEGWGFELGKPTQLTSVLGREPVGPLWPFSVSLWSLEQP
FCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDIHIC
DLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMW
PSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKILELGRHSECVH
VTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVA
QMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYE
SYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVL
MKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLA
EVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWK
QEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSK
NPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQDSLALGKTEEEALKHF
RVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C7GZ24|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPAMTNLMDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQACFSPQLEPGGG
ATPVTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTIPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISA
IGAVVNRKSSNPPLPLPPKRRGPSQVNTCVWEVSTHFKIVLIKGSKVNAEETAKIQVRAG
LFHGTELLCKPAVSSESSGRSEHVWNRTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKS
TKNAHINKYQTIRKSGKVHYPVAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPI
GTIQTNPYTENTTALHIHLPDYNPHTILFPPFDKILEKAAEIAGSSDCLPMGRGGKKFHI
ELKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQVHTVPR
EPVLCIDSGNKLVDEELSQYLLQLVQVLRYEPYYDCALTRFLLNRAQCNRNIGHFLFWHL
RSEMHMPAVAVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSKT
KEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMDSKMKPLWIVYNN
KLLGGDTLGIIFKNGDGTRGLDLTLTWCISMLLMMIHWNKMCLCRIVPYGCLATGDRSGL
IEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKAIEEFTLSCAGYCV
ATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQ
GKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLAL
GKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A8C4BF31|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPGVFGMQDVWEKDGQQVTVEFLLPTGIYLTLEVSCSDTIGTIKKMLWRAARGEPLFGA
LSDPDAYVFTCINLTAEREDLEDEQRRLCDVRPFLPILRLVAREGDRVEKLINTQISHLI
GKGLHEFDSQKNHEVSEFRTKMRAFCEERAQERQRLPWYEWMESSFPCDLEPCSGLLKSS
KFHNFKKVFVNVKFEGSESFMLQLDPQDLPVMLMKNALKKKATVFRPVRQEKPEDYTLQV
LGRWEFIYGKHPLCQFKYIWCCMHEAQTPYLTMVHHSTITKYQEEQSCLTNQVTKTRSSS
KPPPLPLKKQNTTSLWTIQEPFYVQLVQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSN
EVNVSSEPLWDQKLVFDISVGDLPRMTRLCLALYAVVGTTKKARSTKKKNKRADCPLAWV
NTMVFDYKDQLKTGDFSLSAWPSVPDEKSDLLNPMGTVEKNPNIDSAAGLLIRFPNIRPH
PLCYPPLDKEQEEDHMKLKEIVDNKNQTEIFEDEKELLWKLRVEMRDHYPESLSKLLLIG
KWNKHEDVAQMVWLLRKWPDLPVLHALELLDYRFPDPYVRSFTIKCLRKLRDDELFRYLL
QLVQVLKYESYLDCDLTTFLLERALSNKNIGHFLFWHLRSEMHVSSASLRFGLILEAYCR
GNLYHIKSFMKQNEALNKMKALNDFVKSGSQKATRSQTIEDMKVCIRQEAYMEALSDMLS
PLSPSIILSEICTEKCKFMDSKMKPLWLMYKSKVAQADTVGIIFKNGDDLRQDMLTLQML
ELMDVLWKREGLDLRMVPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDA
LLNWLKSKNPGDKLEEAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGH
FLGNFKTKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYKILCRNGTLF
VNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKIFKVKFNEALRESWKTKVNWM
MHSVAKDNR
>A0A851BXB9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calyptomena viridis|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKALGP
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHCSAIIALRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>H2LYJ4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MPPRPSSGELWGMHLMPPSIVVDCLLPNGMILSLECLREATLVTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILSREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDNNGPHSRALYVYPPNVESSTDLPRH
IYNKLDKGQIIVVIWVIISPSNDKQKYTLKISHDCVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPSD
NFTMPSYARRISTATSYMNGETSSKNLWTINGMLKIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLSYDMYILEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEQF
SSPVKFPDMAYVEEHANWNISRELGFNYSHTGLSNRLARDNPLTDNDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHSCINIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWIKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKEDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A3P9H599|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETCYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDFEVQDFRRNILNVCKDAVELRDANGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYSQLPTD
SFVMPSYCRRISTATSYMNGEAAPKSLWTISGGLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLNYDMYILDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYNHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEHF
SSPVKYPDMNAVEEHANWTISRELGFNYNTSGQSNRVARDHALTDSDSEQLKQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKFLADDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNRGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKGEQVSRHFMGNQSLRSFEASPHQLKRFFHVAGSIGLLYETDERCSPWRVD
HQDGLDIPHN
>A0A7L4MEN3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Glareola pratincola|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQGI
>A0A7J5XFH3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dissostichus mawsoni|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVEMRDASGPHSRALYVYPPNIESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYSQLPTD
NFVMPSYSRRISTATSYMNGEASAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSLVKYPEMNAVEDHANWTISRELGFNYNLSGQSNRSARDHALTDSDTEQMRQLSNRDAL
SEITEQEKDFLWRHRHYCMNIPEILPKILLSVKWNSRDEVAQMYCLLKEWPSTRPEQAME
LLDCNYPDPMVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKKETDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDC
VGLIELPTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDLAVDLFTRSCAGYCVAT
FILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGS
QECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLAL
EKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8B9IWI8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amazona collaria|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GPLHIPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKTA
AKPPPLPKKKPNYGSLWSLEQSFYIQLVQGSKVNADEGMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWQQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAAEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMQSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKNNRQ
>A0A4Y6GPC7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVDQEAELEEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDCNGPHSRALYVYPPNVESSVELPRH
IYNKLDKGQIIVVIWVIVSPCNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKPLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYVMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVGNRDPL
SEITEQEKDFLWRHRQDCANMPEVLPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQDLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDV
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A2U9B1I1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MDGQQILVSDEEPKVLREEARRRRRKKAITSSPSTSMDQIAVEFVLPTAARAGNGPDTLL
LEVAGNWTVEQVKAQVWLKAVTSNLCPDFYQRFSPDHCILLYPKKGNMCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESAQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRVELSDRDPRLYSVDPWVTRKPLPEHLLSKVSNNHILLVIHISTVSQTIKVSID
DTPAQVLASFFAKMANKRLLLGIPEDVCEADYVLRVCGREEYLYGGKPLQNFNWIRQSMK
NGEEIHLVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPEFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVVCGKQPQMSNSKGSSYQDNTAGGGGSSHDAKTKSRLLYYVNLLLI
DHRSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAVAILLDKYCYPVV
LPKSRDASRAAPAAAEDAEAGERGQREMPNHLKKQFEAIVATDPLHPLSPEDKELLWHFR
HECLRDPRAYPKLLSSVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQ
VRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFL
RSEIAQSMHYQQRYAVLLEAYLRGCGEAMLQDYRKQVEMTEALQKVTREMKAMSADKYDI
TAQVVFQLRQKLETLQSSGLPENFRVPYDPGLRAGALMIEQCKVMASKKKPLWLQFKRAD
PTTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMI
EIVKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVNEDKFQQAVERFLYSCGGYCVAT
YVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSG
KKSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGR
NEDEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVDKRST
>A0A673HQC2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MCFNDSLIVLSAMPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHI
KLLLWKEAQTYPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRN
CGRAERILDSKIGVLIGKGLHELDALQDQQVKDFRSKMKRVSEEKMQRMQLMSCGEWLRS
CYSTQLGTGSLENLIDKHEGVIKITMHYDQSQVCSVILICKEDIGTRSDYVLRVSGRFEF
LFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLARKTSNPPLPLP
PKKRPPTVSTLSVFPAHQLIKGVLSFVHLVRAGLFHGTELLCKTAVSSESSSRSEHVWNK
TLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHYPIAWVNT
MVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPV
VFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRY
DCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLKVQAFTWYFNMLMQKLEFMIAC
VVHYRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVSELIKLGTIKTK
TKQAHLKEAMMTCLRQTGFIETLSDLQSPLNPNILLAGVHVERCKYMDSKMKPLWIVYNN
KLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIE
VVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVAT
YVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGK
TGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGK
TDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A673J1Q1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMRDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWDQWMEYNFTCDLEPCSVVAQS
GKSCSDKKIFVNVKFEGSEETFVLQQGPQDLPMFLKRNALRKKSTVFRSAKQEKPEDYTL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSINEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCIALYGVIEKTKKRPTKKKNKSSDCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKHLKLREIVDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITKWNK
HEDVAQMVGLLQKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLRDDELFQYLLQLVQ
VLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVSSVSLRFGLILEAFCRGSIF
HIKNLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNP
SIVLCELCADKCKFMDSKMKPLWLMYKNKYDTLGIIFKNGDDLRQDMLTLQMIQLMDVLW
KTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKS
KNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKS
KFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALM
KAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKD
NR
>A0A673HU73|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
SISLLWKEAQTYPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITR
NCGRAERILDSKIGVLIGKGLHELDALQDQQVKDFRSKMKRVSEEKMQRMQLMSCGEWLR
SCYSTQLGTGSLENLIDKHEGDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSD
YVLRVSGRFEFLFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLA
RKTSNPPLPLPPKKRPPTVSTLSVFPAHQLIKGVLSFVHLAVRAGLFHGTELLCKTAVSS
ESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIPWV
NTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQ
PVVFPAFDKVCIYSQYEQHLSCYRICIIVFLFLKEIMERDPLSQLCENEKDLIWTLRYDC
RENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVI
CLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMYMP
AVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVSELIKLGTIKTKTKQAHLKEAMM
TCLRQTGFIETLSDLQSPLNPNILLAGVHVERCKYMDSKMKPLWIVYNNKLLGGDTVGII
FKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSSADTIANI
QKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGNFR
QYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQ
KFDEALRESWTTKVNWMAHIVAHPS
>A0A7L0MX52|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Formicarius rufipectus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKIGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNFQSHESSNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIPSD
AQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQTAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K5MC58|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cardinalis cardinalis|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPTKNIFVNIRFQSGGESFMFQISPWEFPITLMSYAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7L1RRK2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Locustella ochotensis|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWQQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGS
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKAA
SRPPPLPKKKPNHGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
WEVAVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A4W6CSP7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLQH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYCKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCITVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLSDLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYQDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKDWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFMRFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A4W6CSQ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLQH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYCKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKGPTALRHLRQRQHQGH
>A0A4W6CES4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TLPLFSALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRISEERMQRVQMMTCAEWLQACFSPQLEPT
AGTAITDGVNDRLADLKVTIHFDQSQDSASLKVPSSCTSTELMELALKKWLTTHGPEEEA
WRGQYVLRLSQRLEFLCGDHPLIQYKYIRTCMQAKESPHLTLVHTSAVKAMFDKEISTIG
AVVSRKSSNPPLPLPPKRRVPTHTTCVWDVSNSFKIVLVNASKVNAEENAKVQVRAGLFH
GTELLCKPAVSTESSGRSDHTWKESTLEFDISICDLPRMTRLCFAIYAVMDKVKKQKSTK
NPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDINLHCWSSFPDELEEMLNPIGT
IQTNPYTENATALYINFPEYSSHPVVFPPFDKVRQLSVIGRGGKKFHIELKEIMERDPLS
QLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALE
LLDFNYPDQYVREYAVCCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGNR
KIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALNKLKSVNELIKL
GTTKNARSKTKEAMLTKEAMMTCLRQSDNTNRCRYMDSKMKPLWIVYNNKLMGGDTLGII
FKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANI
QLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFR
QYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQ
KFDEALRESWTTKVNWMAHNVAKDNRS
>A0A4W6BVQ4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLQH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYCKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLH
LCVQEYQGQCNPGAVRGVQVCVNSAAATE
>A0A4W6FXK4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MDGQQTQVSDEEPKYLREETRRRRRKKAITSSSSASMDQISVEFILPTVARGGNSPDSLQ
LDVAGNWTVEQVKAQVWLKAVTSNLCPEFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVSNSHILVVIHIGTASQTIKVSID
DTPAQVLASFFTKTANKRVLLGIPDNMCEADYVLRVCGREEYLYGDKPLQNFNWIRQCLK
NGEEIHLVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDGKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQLICLSFHLSGKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEK
SEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDVAAVGEDVEGG
ERGQREMPNHLKKQFAAIVSTDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRWGK
QEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYL
LQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAY
LRGCGEAMLQDYRKQVEMTEALQKVTREMKAMSADKYDVTAQVVFQLRQKLETLQSSGLP
ESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQ
DMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTG
AFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNL
FHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQVCCHDVTSDT
EDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLL
DQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A852A374|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calcarius ornatus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPTKNIFVNIRFQSGGESFMFQISPWEFPITLMSYAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>U3K146|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ficedula albicollis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3Q3G568|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Labrus bergylta|TrEMBL
MPPGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSRNNTISIIKKMVWKNARSEALFG
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNQEVDEFRTKMRTFCEEKAQERQLLPWQQWMEYSFPCDLEPCCSPPTS
AKSKSSKKIFINVKFEACDESFMLQQDPQDPPAALMKSALKKKATVFRSLRQEPEDYTLQ
VNGRWDFIYGKHPLSQFKYIFWCLRNGQNPHLTMVHYSTISKYQDEQGRMCNQVFKSRSS
SRPPPLPLKKQKTSSLWSINEPFCIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVAVSSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEVLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAVLLIRFHNIRP
HPLYYPPLDKYMKLKEIMDNKNYTEFFEDEKEILWKLRAEVRDCFPDSLSKLLLITKWNK
HEDVVQMVSLLRNWPDLPAIHALELLDYSFPDPVVRSFTIRCLRKLSDNELLQYLIQLVQ
VLKYESYLYCDLTTFLLERALSNRKDRTLSVLASQIHVASVSLRFGLILEAYCRGNIHHI
KLLTKQNEALGKMKALSDFVKSGSQKMTVDDLKLCIRQESYLEALSDLLSPLNPSIILAE
ICADKCRFMDSKMKPLWLMYKNPCIQGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKE
GLDLRMIPYGCLSTGNKMGLIEAVKHSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNP
DDKLDKAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKMG
INRERVPFILTYDFVHVIQQGKTNNSEKFERFRECCEQAYKILCRNWSLFVNLFAMMKAA
GLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A7L3VE19|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Molothrus ater|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A669CXT5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
YTTGQPCSAVVMLNTESRRRRRKKAITSSCSNSMDQITVEFVLPTAARGGSGSDTLQLDV
AGNWTVEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDC
IRYWRALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLL
TPRRIELSERDPKLYSMDPWVTCKPLPEHLLSKINNGHILVVIHIGTASQTIKVSIDDTP
TLVLVSFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLKNGE
EIHLVLEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKF
RVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNIKIK
DLPKGARLNLQVICGKQPQIPNSKGSSYQESTAGRKTKSRLLYYVNLLLIDHRSLLRQGE
FILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRD
WAVGGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHECMRVPRAY
PKLLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLE
TLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSKHY
QQRYAVLLEAYLRGCGENMLQDFRKQVDMTEALQKVTREIKTMSADKYDVTPQVVFQLRQ
KLENLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADSTTLSKDPIG
IIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIA
NIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHN
DNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKF
QDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLL
DQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A669DC28|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDSEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEITFSLYDMAVDL
FTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVL
TQDFLIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSF
DDIAYIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>I3JM92|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRCKMFRISEERMQQIQMMTFSEWVQACYSPQLEPA
AVTAITAGVNDAPADLKVIIHFDQSQDSASLKVSLSCTPNELMEQALKKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKDTPHLTLVHTSAVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRRAPTQVQTCVWDVPKPFRIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSNESSGRSEHTWKDNTLEFEISVCDLPRMTRLCFAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHPIVFPPFDKVTQHSIMVSADCVSIGRGVKKFYMELK
EIMERDPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIWP
KLSPRDALELLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTHF
LLERAQRNRQIGHFLFWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQVEALSKL
KSVNELIKLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDINV
EKCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLD
LRIVPYGCLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDA
LDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKR
ERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLP
ELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C8H603|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MEQQVGDEEEPQPVVLRAEIRRRRRKMKAFTSTLSVAVDQIAVEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCVRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELSDRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPENVCEADYVLRVCGREEYIYGNHPVRNFHWVRQCL
KNGEEIHLVLELAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVYTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNAWLEFN
IRIRDLPKGARLSLQVNCQHLCCGGGSGSGSGSHDGSKTKSRLLYYVNLLLVDHRSLLRQ
GEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYPVALPKSRDGKA
AGGEGREAEGGERGQREMPNHLRKQFEVIVETDPLHPLSQEDKELLWHFREECMRHPRAY
PKLLGSVLWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLE
TLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHY
QQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQVVFQLRQ
KLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTTLSSDTIG
VIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTIA
NIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLGVGDRHN
DNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFQKF
QDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEEAQRHLL
DQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A3P9QIB4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia reticulata|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRNSSGPHSRALYVYPPNVESTQELPKH
IYSKLDKGHIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKHQRDSANTNPLRHLRQREYTGHRQGGDKTTSVLLHLVINGAKPNLCF
RAESLD
>A0A2K5NKZ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cercocebus atys|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSSGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C8JFI9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPRPSSGELWGMHLMPPSIQVDCLLPNGMILTLVCTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEETP
CLELEFDHFSNPVKFPDMPAIEEHANCNISRELGFNYCHTGLSNRLARDNPLTDSDNEQL
RLVCNRDPLSEITEQEKDFLWRHRHYCGTIPEILPKILLAVKWNSRDEVAQMYCLLKDWP
AIKPEQAMELLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLAR
FLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEK
LINLTDLLKQEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRM
MSSAKRPLWLNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDL
RMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYD
QAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRER
VPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMP
ELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A7F8RWJ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptonychotes weddellii|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTMRVPTRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFRVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLNMWPSVPDEKGELLNPTGTVRSNPNTESAAALIICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEELQLREILERRGSGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALSDFVKVSSQKTTKPQTKELMHLCIRQ
ETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDTQYLKCGRSWGVGRVVGHEPLCGAWFM
HNDAAPSSAPPVQKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A5F5XD52|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Felis catus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRMLPYGCLSIGDCVGL
IEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVA
TFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKG
AQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLA
LDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K6YBJ4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alca torda|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQATDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPLLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K8DP91|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eulacestoma nigropectus|TrEMBL
MELEDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PGMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENAMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A671U1R8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MPPGKYGMQEEWEKEGDQGIVMDFLLPTGIFLKFPVSRHDTIKSIKKMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEVKAQERQALPWQQWMEYSFPCDLEPCSSPPVC
GSVKSKNTKKIFINVKFEACDESFMLQQDPQDLPVALMRSALKKKATVFRSVRQEPEDYT
LQVNGSWEFIYGNHPMCQFKYIFSCLRNGQNPHLTMVHHSTISKYQEEQGRMCSQVFKSR
SLSRPPPLPLKKNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SSEVTVSSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFSNIR
PHPLYYPPLDKISDVERNGDAAIATKEEVISYFLILTRSRSGLLLFFEDEKELLWKLRTE
VRDRYPESLSKLLLITKWNKREDVVQMVSLLRNWPDLPAIHALELLDYSFPDPAVRSFTI
RCLRKLSDDELLQYLIQLVQVLKYESYLDCDLATFLLERALSNRRIGHFLFWHLRSEIHV
ASVSLRFGLILEAYCRGNIQHIKLLTKQNEALGKMKALSDFVKSGSQKMTVDDLKLCIRQ
ESYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNTCAQGDMVGIIFKNGD
DLRQDMLTLQMIRLMENLWKKEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDN
IMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRE
YCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVK
FNEALRESWKTKVNWMMHSLAKDNRP
>A0A851VMV7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Copsychus sechellarum|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWQHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVRDPEVSDFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPMAKGLGA
GSQQIPSKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIRKQATVFRHETLQRPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAILAMRDEQNSCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKQQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A671TP29|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSSVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTDQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A671VTQ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MPPAMTDLLDIWAAHSPLAGHALDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRMSEERMQRVQMMTYTEWLQACFSPQLEPT
AGTAITDGLNDRPADLKVIIHFDQSQDSASVKVQSSCTPMELMELAVRKWLTTHGPEEET
WRGQYVLRVSHCLEFLCGDNPLIQYKYIRTCMQAKEPPHLTLVHTSNVKAMFDKDITAIG
AVVTHKSSNPPLPLPPKRRVPTQVQTCVWDVSIPFKIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESSGRSDHTWKDSTLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKST
KNAHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGELILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSPHSIIFPPFDKILEKAAEILKANDCVPLTRGGKKFHIE
LKEIMERDALSQLCENEKDLIWTLRHDCIENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLCPRDALELLDFNYPDQYVREYAVRCLRDMSNEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALS
KLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQISYSETLSDLYSPLNPNVLLSGI
NVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDRLWKEAN
LDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSG
DALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A6J0D2B0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Peromyscus maniculatus bairdii|TrEMBL
MPPGVDCPMDFWTKEESQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEVAAHRQQLGWEDWLQYSFPLQLEPSARSWRA
SILRVTNRALLVNVKFEGSEESFTFQVSTNDMPLALMACALRKKATVFRRPLVEQPEDYA
LQVNGRHEYLYGSYPLCQFQPSSVSLWSLEQPFCIELIEGSKVNADERMKLVVQAGLFHG
NEMLCKTVSSSEVSVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKK
SKKADCPIAWANLMLFDYKDQLKTGECRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAA
LVICLPEVAPHPVYFPALEKILELGRHGERGRVTEEEQLQLREILERRGSGELYEHEKDL
VWKLRHEVQERFPEALARLLLVTKWNKHEDVAQLSQMLYLLCSWPELPVLSALELLDFSF
PDCYVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFL
FWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTT
KPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEE
AGSAGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEV
VLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATY
VLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKT
NNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKT
EEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>F7E9G2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodelphis domestica|TrEMBL
MDLEDHEPVVLREDHRGRRRRMKPQSAGISSSSMERIPIEFILPTSHQNTKATETVILEA
AGNCNVEQVKAQVWMQAMETSTTMQFYHQSSPEQFLLLYQKKGQWYEIYDKYQLIQTLDC
VKYWKALQKNMGQIHVVQRQPPTEETREFQQQLNDLIGYDVTNMSNVHDDELEFTRRRLV
TPRMMEVARRDPKLYAMHPWVTSKPLPTYLLKKIVNNCIFIVIHRSTTSQTIKVSADDTP
GTILQSFFTKMAKKKSLMDIPESQSELDFVLRVCGRDEYIVGETPIKNFQWIRHCLKNGE
EIHLVLDAPPDPGQDEVRKEEWPLVDDCTGVTGYHEQLTINGKNHERVFTLSLWDCDQRF
RVKIRGIDIPVLPRNTELTVFVEANIQHGQQVLCQRRTTSKPFTEEVLWNVWLEFGIKIK
DLPKGAILNLQIYCGKATAQSSKAEISSFETKGKTQLLYYVNLLLIDHRFLLRHGEYVLH
MWKISGKGEDQGSINADKLTSATNPDTENSMSISILLDNYCHPIALPKHRPTPDPEGDRV
RGEMPNQLRKQLEEIIATDPLNPLTAKDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEI
VAKTYQLLARREAWDQSDLDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQL
VQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRG
CGMAMLEDFTKQVQVIRMLQKVTIDIKSLSAEKYDVTSQVIAQLKQKLENLQNSNLPKNF
RVPYDPGLRAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDML
ILQILRIMGSIWEAESLDLCLQPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFK
DEVLNHWLKEKCPIEEKFQAAVEKFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKSSLHFQKFQDICVKAYLALRQH
TNLLIILFSMMLMTGMPQLTSKEDIEYIRDTLTVGKNEEDAKKYFLDQIEVCRDKGWTVQ
FNWFLHLVLGIKQGEKHSA
>A0A7L2ML59|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhadina sibilatrix|TrEMBL
QLLWKQAHSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNC
DPGEKLDSKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTY
PPEQEPVIPESFQDKLYGGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHG
KEDEEVDPADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQ
EMIAIEAAINRKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRA
GLFHGTELLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKK
STKTMNPSKYQTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNP
MGTVQTNPYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKF
YVVLKDIMERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQAL
LQIWPKLLPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDC
ALSRFLLERALGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVE
ALNKMKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVE
KCRYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDL
R
>A0A2I3LHT4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Papio anubis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7N4V7Y6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sarcophilus harrisii|TrEMBL
MPPGVDCPMEFWSKEENQIVEVDFLLPTGVYLNFPVSRNANLSSIKEVLWHNAQSEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVARQGDRVKKLINSQISLL
IGKGLHEFDSLGDPEVNDFRTKMGQFCEEAAAHRQQLGWEAWMHYNFPLQLEPSARGLGA
GALRGPSRTLFVNVKFEGNEESFTFQVSPNDFPLALMACALKKRVTVFRQPALERPEDYT
LKVNGKYEYLYGSYPLYQFQVSCPCPPQPSSVSLWALEQPFCIELIQGSKVNADERMKLV
VLAGLFHGNEMLCKTVSSSEVTVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAK
KARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWSSVPDEKGELLNPMGTVWSN
PNTESAAALVICIPEVAPHPVYYPTMEKVSGGPAQGSPLGSGPGGGLYRGLPRLLLAGRL
ILELGKNGEHGRFTEDELQQLREILERKVAGELYEHEKDLVWKMRHEIQEQFPEALARLL
LVTKWNKHEDVAQVALPSPSSWPELPVLSALELLDFSFPDRHVGSFAIQSLRKLTDDELF
QYLLQLVQVLARVPPDRVTVPAGRPHRKIGRSSLSSEMHVPSVALRFGLIMEAYCRGSNH
HMKALMKQGEALNKMKALNDFVRVSSQRTTKPQTKELMHVCLRQEIYMEALSNLQSPLNP
STLLSEVCVEQCTFMDSKRSRGSQAAGEAAGSCSPGIIFKNGDDLRQDMLTLQMIQLMDV
LWKQEGLDLRMTPYGCLSMGDRTGLIEVVSHSDTIANIQLNKSNMAATAAFNKDALLNWL
KSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNF
KTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRSYCERAYTILRRHGLLFLHLFA
LMRAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFNEALRESWKTKVNWLAHNVS
KDNRQ
>A0A2R9A4C9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan paniscus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKRTAQKQFLHEIL
SLKITEQEKDFLWSHRWLIHNYLSPLNMIYCLSHTQMYCLVKDWPPIKPEQAMELLDCNY
PDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHF
FFWHLKSEMHNKTVSQRFGLLLESYCRACGVYLKHLNRQVEAMEKLINLTDILKQEKKDE
TQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENP
DIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVG
LIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRPCAGYCV
ATFISGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISK
GAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTL
ALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A2R9AJY1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan paniscus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRALPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3Q3A7A2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Kryptolebias marmoratus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLNTIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKIHHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKHPISQYKYIRSCIMLSRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEASSKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTEADTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A3B3C2I1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias melastigma|TrEMBL
MDRRSIQVSDEEPEAPHCRRRRRKKAITPSSCASMDQITIEFVMPSVARGGNSPDVLLLD
VAGNWTVEQVKAQVWMKAVTLNLCPDFYQRLSPDHCILLYQKKGTVCEIYDKHQVFQTLD
CIPYWRALKKGVGRIQMVPRPQPSEESLQYQRYLNCLIGYDVTDVSNVHDDELEFTRRKL
LTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVNNGHILVVIHIGMVSQTIKVSINDT
PSQVLASFFAKTANKRVLLGIPDDVCEADFVLRVCGREEFLYGEKPLQNFNWIRQCLKNG
EEIHLLLEKPPDPELDVVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRK
FRVKVLGIDIPTLPKVPELVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKI
KDLPKGARLNLQVICGKPTQTPAGKGSSHYDNSGGTGSSEGKTKNRLLFYVNLLLVDHRS
LLRQGEFILHMWKMPEKSDESSSSINADKLTSATNPDKSSSMAIAILLDKYCYPVVLPKS
RDVGRDCGAGEETEGGERGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRQECMR
DPRAYPKLLGSVKWGKQEDVLATHRLLERNNAWDTSGLDVGLAMQLLDCHYSDSHVRSMA
VRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIA
QSMHYQQRYAVLLEAYLRGCGESMLQDFRKQVEMTMALQRVTREVKAMSADKYDVSAQVV
FQLRQKLETLQSSGLPETFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLS
KDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKD
ATTIANIQQRVVGSTGAFKDEILHQWLRDKCVSEDKFQQAVERFLLSCGGYCVATYVLGI
GDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSP
HFLKFQDVCVKAYLALRHHTNLLIILFSMMLMTGTGPGLAVGM
>A0A8C8RNI3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pelusios castaneus|TrEMBL
MELGNYEQPVVMREEKKRRRRGMKPYCAASNLSSMELISIEFVLPTSNIHTKVPETMLLE
IAGNCTVEQMKAQIWIRAIEMSQTTDFYRKFTPDQFILQYQKKGQLYEIYDKHQVIQTLD
CILYWKMLQKKIGKIFVVQKQKPTEVVQEFQTQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRIIEVARRDPKLYSMHPWITSKPLPEYVLKKITNDNIFIIIHRGTTSQKIKVSIDDT
PDVILQRFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDDPPDPNEDEVQKEEWPLVDDCTGVSGYHEQLTIDGKDHERVFTISLWDCNRK
FRAKIVGIDIPVLPRNTELTVFVEANIQHGQQLLSQRRTMSKPFTEEVLWNMWLEFDIKI
KDLPKGALLNLQIYCGKAQALSTKPSLQSHDSPNSDSKCKTQLLYYVNILLIDHRSLLRS
GEYVLHMWKISGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQRDRTRAEMPNQLRKQLEEIIATDPLNPLTPEDKELLWHFRYESIKHPKAYPKMLSSVK
WGQQEIVAKTYQLLAKKEAWDHSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMEQVQIIKLLHKVTMDIKSVSAEKYDVTSQVITQLKQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCAIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITES
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQETCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C9GC41|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Piliocolobus tephrosceles|TrEMBL
MPPGVDCPMEFWTKEENQSIVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSTEVSVCSEPVWKQRLEFDINICDLPRMARLCFALY
AVIEKAKKARSTKKKCKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNP
TGTVHSNPNTDSAAALLICLPEVAPHPVYYPALEKLLGGMLWACRGGRPELLWMCLHARD
SAPSSMIGVVTPCLGVLPGLVQAPGDAECNCLLQILELGRHSECVHVTEEEQLQLREILE
RRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQDALPAVSWPELPV
LSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDR
ALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A4W5RCH6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MEQQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVTMDQIPIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKGAALWVTLCCLPAPSLFCVTNSHILLVIHRNK
ASQTIKMSVDDTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNQPVR
DFHWVRQCLKNGEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHER
IFTISLWDCHRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEV
LWNTWLEFNIRIRDLPKGARLSLQVSCGKAQTQISKGTYQDNGGSPTKSRLLYYVNLLLV
DHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMVVAILLDKYCYPVAL
PKSREGKEAGGEGREAEGGKRGQREMPNHLRKQFESIVETDPLHPLSQEDKELLWHFREE
CMRHPRAYPKLLGSVRWGRQEAVLTTHGLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVR
SMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRS
EIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSA
QVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPT
TLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYV
LGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKK
SSPHFQKFQDVCVRAYLALRQHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPE
EEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A8C6ZTK2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothoprocta perdicaria|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRVSEEKIQSLVGLSWMDWLKHTYPPEQEPVIQE
SFQDKLYSGNLVVAIHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAAN
RKSSNLPLPLPPKKTRATTSVWDICNPFKIVLLKGYKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNETLEFEINVCDLPRMARLCFAVYAVMDKVKTKKSTKAMNPPKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELILHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIAKSSDNAAMAGRGGKKFYVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRESFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLPPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCKYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEDAYLILRKHGNLFITLFALMLTAGLPELTSIKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C7TFZ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MLFRNSWVLVPAMPPAMTDDLDLWAAHSQLCGEDLVTVDFLLPTGIYIQMDVPREATIQH
IKLLLWKQAQSYPLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFCPMLKLVTR
NCGRAERLLDSKIGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQ
ACFSPQLEPGGGATPVTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQAL
RKWLTTHGPEEEGRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVS
TVQAMFEKEISAIGAVVNRKSSNPPLPLPPKRRGPSVSSPFKIVLIKGSKVNAEETAKVQ
VRAGLFHGTELLCKPAVSSESSGRSEHVWNRTLEFDITVSDLPRMARLCFAVYAVMDKVK
KQKSTKNAHINKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEM
LNPIGTIQTNPYTENSTALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCSSMGRGGK
KFHIELKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQ
ALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYY
DCALTRFLLNRAQCNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYSRGSIPHIEVLKKQ
VEALSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSV
LLSGINVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLL
WKEANLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLK
EKNSGDALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFK
SKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFAL
MLTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVK
DNRS
>A0A8C3A2Y1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFAEARKYPLYH
LLQEESSYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSHALYVYPPNVESSSQLPQH
IYRKLDKGRLIVTIWVIVSPSNSKQKYTLKVNHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLAYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGVSSRLACDSRTSAADAEQLHSLSSRDP
LYELSEQEKDFLWRHRHYCVNMPESLPKLLMSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A8C2ZWD2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MDGQQTQVSDEEPKVLREDTRRRRRKKAISSSSGASMDQITVEFVLPTAARGGSGPDTLP
LEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDAKLYSMDPWVTRKPLPEHLLTKVSNAHVLMVIHIRTASQTIKVSID
DTPAQVLVSFFAKTANKRVLLGIPDSMCEADFVLRVCGREEYLYGDEPLQDFNWIRQCLK
NGDEIHLVLEMPPDTDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFSEEVLWNCWLEFNI
KIKDLPKGARLNLQVVCGKQPLTPNSKGASTYQDNTAGTGGHDGKTKSRLLYYVNLLLID
HRSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASAMAVAILLDKYCYPVVL
PKSRNAGNRDDGGRDAGGEEAEGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLW
HFRHECIRDPRAYPKLLGSVRWGRQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYS
DAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLF
WFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTREMKAMSADK
CDITAQVVFQLRQKLETLQLSGLPESFRVPYDPGLRAGALMIEQCKVMASKKKPLWLQFK
RADPTTLSRDPIGIIFKDGDDLRQDMLILQILLIMESIWETETLDLCLLPYGCISTGNRI
GMIEIVKDATTIANIQQSVVGSTGAFKDEILSQWLRDKCVSEDKFQQAVERFLYSCGGYC
VATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMG
TSGKKSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALT
VGRSEDEAERHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A8C9RTL6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MPPAMTDILDIWAADSQLSNEDYVTVDFLLPTGIYIQMEVPREATIQHIKLLLWKQASTY
PLFAFLGEMESHMFECVNQSAVHEALEDETRRLCDVRPFLPVLKLVPRNCGRAERLNSKI
GTLIGKGLHELDALQDQEVKDFRVKMFRISEEKMQRVQMMTWMEWLQSCFSPQLENGVID
GLQEKLFDGALKVIMHFDQSQDTASLMVSPTITPRELTEQAVRKWITTHGPEEDESSCGE
FLLRVSNKLEFLYGEHPLIHYKYVRACVIGKDTPHLTLVHCGMVQAMFEKELSAIGAVVN
RKTSNPPLPLPPKRRGPSVSFKIVLVKGSKVNAEETAKVQVRAGLFHGTELLCKPSVSTE
SSGRSEHVWNHTLDFDIAVCDLPRMARLCFAIYAVMDKVKKQKSTKNAHINKYQTIRKAG
KVHYPIAWVNTMVFDYRGHLKTGDNILHCWSSFPDELEEMLNPIGTVRTNPYTENATALH
IYFPEYSSCPVVFPPFDKVRTGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCR
ENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVRC
LKDMSGKSEFGWMNNDDELSQYLLQLVQVLRYEPYYDCALTRFLLERAQTNRKIGHFLFW
HLRSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKAVNELIKLGTIKNARK
TKEAMLTKEAMLTCLRQTGFTETLSDLHSPLNPSVVLSGINVEKCRYMDSKMKPLWIVYN
NKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLI
EVVSAAETIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALDRAIEEFTLSCAGYCVA
TYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQG
KTGNTEKFGNFRQYCEDAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALG
KTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAHNRS
>A0A7J7UE06|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myotis myotis|TrEMBL
MCFNFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
TQIHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
ESSILENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMNPIKINELAIQKRLTIHWKEDE
VSPYDYVLQISGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGT
ELLCKTIVSSEISGKNDHVWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTIN
ASKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQT
NPYTENATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEI
LDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKL
PPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQFLFWHLRSEVHIPAISIQFGVILEAYCRGSVGHMKVLSKQVEALNKLKT
LNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCIILSELYVEKCKYMDS
KMKPLWLVYNNKVFGEDPVVVMFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGC
LATGDRSGLIEIVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEF
TLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDCRS
>A0A7J8A031|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myotis myotis|TrEMBL
MPPGVDCPMEFWANEESQSVAVDFLLPTGVYLNFPVSRNANLSAIKKALWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRVKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKQEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKSR
TKPPPIPMKKPSSVSLWALEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVCSNPNTESAAALVICLPEVAP
HPVYYPALDKILELGRHGEHGRATEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RWPEALARLLLVTKWNRHEDVAQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPQTKELMHLCMR
QETYLEALSHLQSPLDPRILLAEVCVEQCTFMDSKMKPLWVMYSNEEAGGDGSVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A087YMR4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia formosa|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRNSSGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKISHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLTRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEASSKSLWSINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLPYDMYIPDVPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMNAVEDHANWIISRELGFNFNLSVNHSGTQQSSRAARDHALTESDGEQMRQL
SNRDPLSEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDDVAQMYCLLKEWPSIR
PEQAMELLDCNYPDPVVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDSPLARFLL
KKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLIN
LTDILKQEKKDETQKVQMKFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLEECRIMSS
AKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRML
PYGCLSLGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGETYDLAV
DLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPF
VLTQDFLIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQ
SFDDIAYIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8C3LLP5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysolophus pictus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVNFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYTLQVNGKY
EYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINSIANPPKMAVKPPPLP
KKKVKGSSPCGFTVSYSFSSPQLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFD
INICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVMNPFKCYTVCDCPIAWVNVMLFD
YKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALLICFPNVASHPVYYPS
FDLTASLWAEQGLWLRLSSLYALCCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRHD
IRDQYPQALAKLLTITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHV
CMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLACAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCEKAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8B9ZY56|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas zonorhyncha|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKAPMC
AGDSAYTGLEVLHFQPCESFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYTLQV
NGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANTPKMSPKP
PPLPKKKVKGHIFSYFFSPQLVVQAGLFHGNEMLCKMVSSSEVNVCSEPVWKQRLDFDIN
ICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVSKDCPIAWVNVMLFDYKDQLKTGEC
CLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPNVASHPVYYPSFETTPHCTRR
SRGGEFLRSSHLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNK
HEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDNELFQYLLQLVQ
VLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTH
HIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCMKQETYLEALSHLQSPLNP
SIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIFKNGDDLRQDMLTLQMIQLMD
VLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNW
LKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGN
FKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLF
ALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNV
SKDNRQ
>A0A7N6BIT4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPGKYGMQGEWEKEGDHEIMMDFLLPTGIFLKFPVSRNDTIKTIKRMVWKNARSEALFT
ALGDPDAYVFTCINHTAEREELEEESRRISDVQPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEVQKNHEVNEFRTKMRVFCEEKAQERQRLPWHQWMEYSFPCDLEPCCSPQCG
SSRSKNTKKILINIKFEASDQDPQDPPLVLMRSALKKKATVFRSVRQEPEDYTLQVNGRW
EFIYGNHPLCQFKSACVFPLQLVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQKLEFDI
NVADLPRMGRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLL
STWPSVPDDKSDLLNPMGTVERNPNVDSAAGLLIRFANIRPYPLYYPPLDKVLVLKTLYQ
SLKCLFFVKLKEIMDNKNYTEFFEDEKELLWKLRAEVRSSYPESLSKLLLITKWNKREDV
VQMVSLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLRNLSDDELLQYLIQLVQVLKY
ESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIRL
LTKQNEALAKMKSLSDFVKSGSQKMTVEDLKLCIRQESYLEALSDLLSPLNPSIILSGIC
ADKCRFMDSKMKPLWLMYKNPGTQGDMVGIIFKNGDDLRQDMLTIQMIQLMENLWKKEGL
DLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNCSNSAATAAFNKDALLNWLKSKNPGD
KLDQAIEVFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGIN
RERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGL
PELTSFKDIQYLKDSLCLGKSDDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A3Q1J7B1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPGKYGMQGEWEKEGDHEIMMDFLLPTGIFLKFPVSRNDTIKTIKRMVWKNARSEALFT
ALGDPDAYVFTCINHTAEREELEEESRRISDVQPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEVQKNHEVNEFRTKMRVFCEEKAQERQRLPWHQWMEYSFPCDLEPCCSPQCG
SSRSKNTKKILINIKFEASDESFMLQQDPQDPPLVLMRSALKKKATVFRSVRQEPEDYTL
QVNGRWEFIYGNHPLCQFKYIFSCLRNGQNPHLIMVHHSTISKYQEEQGRMCNQVYKSCS
LSRPPPLPLKKNTSSLWSINEPFCIHLVQGSRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVCSEPLWDQKLEFDINVADLPRMGRLCFALYAVIEKAKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVERNPNVDSAAGLLIRFANIRP
YPLYYPPLDKVLVLKTLYQSLKCLFFVKLKEIMDNKNYTEFFEDEKELLWKLRAEVRSSY
PESLSKLLLITKWNKREDVVQMVSLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLRN
LSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVSL
RFGLILEAYCRGNIHHIRLLTKQNEALAKMKSLSDFVKSGSQKMTVEDLKLCIRQESYLE
ALSDLLSPLNPSIILSGICADKCRFMDSKMKPLWLMYKNPGTQGDMVGIIFKNGDDLRQD
MLTIQMIQLMENLWKKEGLDLRDKLDQAIEVFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERA
YKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLCLGKSDDEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A8C6RJQ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nannospalax galili|TrEMBL
MELENYEQPVVLREDNLRRRRRMKPRSAVGSLSSMELIPIEFVLPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVMADFYHRMGPDNFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHKSPGQIHVVQRHGPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDARLYAMHPWVTSKPLPDYLSKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFAKMAKKKSLMNIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCGKAPALSGKASAETQGSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKAEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQRVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMETIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPYFQKFQDVCVRAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEGDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A6J2DKJ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zalophus californianus|TrEMBL
MPPGLDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRGPTRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLYQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFRVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEELQLREILERRGSGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALSDFVKVSSQKTTKPQTKELMHLCMRQ
ETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDTQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A6J8C2C2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mytilus coruscus|TrEMBL
MRYIITIEGFQLTAICYHSTYRLNVLSGWLNVDDSLHELQTANDLGQLDIDFLLPNGICV
PLQVDIDRPLDQIKQELWKQAANYPLFQQLATFDKYGFLYISSEGLKEDVMDESVGIAEL
RLAASFLKVVEKPADDKRKTIDRQINSLIGMKGSNYIQAQHSVSKAEISEFRQKMTTYCN
NDILKQANQDPTGLVYFEYKHPCRLRSTRDLPPDVENFVINHIVLTVIVEEIGASYKLKV
NKMSTPDELVKMTVDKWSSKSGLKTKDCNDYILQVLGMKDFLYGDNPLVMFKYVYSCIVK
NTAPEFWLKTKSSVVEKQEVSQPHKSSRSSFQEERRNTVRSEKRSGHCVWDIHNNFYITL
HTACNVQVPENCRSLVRLCVGVFHGPDPLCSIQETKEVSVSQDGLCSFNDCINFDIKVQD
LPQMSRLCFGLHSKKGKEPLLLAWANIPIFDYKSNLQKGKLKLPLWPRSELIQQEESYCF
PVGTVATNPQGDCSMIEFSVPDFTKKGSIYYPPIEKVLELASTHIEVPGMPGSTTWRPNK
NIVQQLDSILKANQYTVIQMLDEQQKQLIWWMRYDIRDKFHEFPHALLYVLYSVSWDNHI
EVSKMQALLQTWPTLEADQALTLLDFTFPDKYVRKKATEWLDELTDEELAQYLLQLVQAL
KYENYLNCDLVKFLLRKALQNRNIGHKLFWLLKSDMHDPSVTVQYGLIIEIYLKANPSHM
SILDRQQIILQKLKSITEIHTKATNLKKKGKEKDDSPLQKVMQMGAYKEAFCNIYSPITL
MYKLDKIVEKSCKVMDSKKKPFWLEWTNADEKGQNIQLIYKCGDDLRQDMLTLQILEVMD
TIWQSEGYDLRLNPYGCVATGNEEGMIEVVQKSLTLAGIQKWRKQGLDKNSLYDWLKHKN
PSEHSLQRAVEEFKLSCAGYAVATYILGVGDRHNDNIMMKETGQLFHIDFGHFLGNKKTK
FNIRRERVPFILTSHFEYVIKDGEKKPQNFHDFKDICERAYLIIRSRAPLLIQLFMMMLS
SGIPQLNNVSDIDYIKEVLALNSTQDEALEKFRKKFKEAQDNSWSTTVNWWFHMRAH
>A0A672MKA5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQS
GKSHSGKKILVNVKFEGSEETFVLQQDPQDLPMFLKRNALRKKSNVFRPAKQEKPEDYTL
QVNGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKFQEEQGGLSNQVSRTRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKVKLLILFTCLFIYLHLYID
CPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRF
PNIRPHPLYYPPIEKLNELGMNGEKVVATKEEMVGLLRKWQDLPAIHALELLDYSFPDPH
VRSFTIRCLGNLRNDELFQYLLQLVQVLKYESYLDCDLTCFLLERALSNKKIGHFLFWHL
RSEMHVPSVSLRFGLILEAYCRGSIFLIKSLMKQNEALNKMKALNDFVKSGSQKATRIQT
TEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKDKYDHVG
IIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIA
NIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFER
FREYCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQTLWHWGNLRRKH
>A0A7L2SZB0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pomatostomus ruficeps|TrEMBL
DSIMPPAVTDSLDIWGVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQA
HSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPMKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISNPFRIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGHLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMTGRGGKKFYVVLKDI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7L2TCT2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pomatostomus ruficeps|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
ITGNCTVEQMKAQVWMRALETSQSTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEDQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLARKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A672TCA7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MEHQASDDEPPVVRREENKRRRRKMKAFTSTSAVLTDQIAVEFVLPTTNKNSKNPDILHL
DVTGNWTIEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVVRQQPTEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDPKLYSMDPWITTKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKN
GEEIHLVLERPPDPEQDVVQKEEWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVNHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERG
QREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEA
VAITHCLLERSTIWDRSSLDVGLALQLLDCHFSDENVRTMAVRKLETLEDDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALGSMRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRG
CGEAMLQDFRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDSF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLCEKCVNEEKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFLGISKERVPFVLTPDFLYVMCTTDKKSSPNFLQFQNVCLKAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQ
FNWFLHLVLGIKQGVEKRSA
>A0A672MAW2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSAELPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKITHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDEYLLEKHPLSQYKYIRSCITLGRLPHLMLVSKDSLYSQLPSS
GFMAPSYSRRTPQPSPCPGGGDPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDEQQIEEHANWSISRELGYSYCLGLSSRLVCDSSISPADAEQLRTLCSRDP
LYEISEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQIYCLLKDWPLMQPESAL
ELLDCNFPDPMVREFALRCLIQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIRDKNKGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKNQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A672LHX8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDGTRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYSMPLEAGSLE
NLIDKHEGIIKITMHYDQSQVSSVNLVCITELMDQALKKWQTTHCPEEDIGFRSDYVLRV
SGKLEFLFEDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIGSVLARKTSN
PPLPLPPKKRLPTASTLFPALQLMQGVLSFVRAGLFHGTELLCKTAVSSESSSRSEHVWN
KTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHYPIAWVN
TMVFDYRGQLKTGDIILHCWTSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQP
VVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLR
YDCRENFPQSLPKLLLSVKWSKHEDMTQLQALLQIWPKLSPRDALELLDFNYPDQYVREF
AVYCLRDMRNLIRNAEFPNVCFCVCVSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERA
QSSRKIGHFLFWHLRSEMFMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNE
LIKFGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGINVERCKYMNSK
MKPLWIVYNNKLLEGDTVDIIFKNGDDLRQDMLTLQILRLMDLLWKEAKLDLRIVPYGCL
ATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTH
DFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQ
YLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A556VWE9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bagarius yarrelli|TrEMBL
MPPAMTDQLDLWAEPVTDGSDQVAVDFLLPSGIYIQMDVPRESTIQQIKQMLWKQAQVYP
LFSLLGEMDGHIFECVNQAAVHEELEDETRRLCDVRPFLPVLRLITRNCGRAERLLDSKI
GVLIGKGLHELDALQDQEVKDFRSKMQRISEEKMQSVQMLSWVEWLHSFFSPQIEVGPVD
GFSDKNDGWIKITMHYNLSQDTTSLKVLLSCTAPELMNQALKKWLTTHGLGEDEDCVGNY
VLRVSDRLEFLFGEHPLMYHRQMHTCVWDVQAPFKITLVKGIKVNAEETAKVQVRAGLFH
GTELLCKPAVSSESSGRAEHIWNKTLEFDISVCDLPRMARLCFAIYAVMDKVKKQKSTKN
MQINKYQTIRKAGKVHYPIAWVNMMVFDYRGQLKTGDIILHTWSSFPDELEEMLNPIGTT
QTNPYTENATALHIRLPEYSTHPLTFPPFDKILEKAADIAGSADSMSMGRGGKKFYIELK
EIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWP
KISPRDALELLDFNYPDQYVREYAVSCLQDMSDDELLQYLLQLVQVLRYEPYYDCALTQS
EIHMPAVSVQFALLLEAYCRGSIPHIEVLKKQVEALGKLKAVNELIKLGTIKAKNKNKEA
QLKEAMMKCLRQTGYSEILTDLQSPLNPQILLADVIVEKCRYMDSKMKPLWIVYHNKLLV
GNTLGIIFKNGDDLRQDMLTLQILRLMDMLWKEANLDLRIVPYGCLATGDRTGLIEVVSS
ADTIANIQKNSSNMAAAAAFNKDALLNWLKDKNPGEALEKAIEEFTLSCAGYCVATYVLG
IGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNT
EKFGSFRQYCEDAYLILRKNGNLFITLFALMLTSGLPELTSVKDIQYLKDSLALGKTDEE
ALKQFRQKFDEALRESWTTKAKNALAHAVQSARHDSDLLREQYEEEQEAKAELQRSLTKA
NAEVAQWRTKYETDAIQRTEELEEAKSNGAATTCCKLRNLSSLVSSCSIARAKGNEVFQS
PPWHYQQVRTGKRGTEYQPNNIKRKKTHGWIKRISTQGGIEVILRRMLKGRKSLSH
>A0A5E4CMU4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Marmota monax|TrEMBL
MCFSFIMPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRIFSEEKIQSLVGLSWIDWLKQTYPPEH
EPSTLENLEDKLYGGKLIVAVHFENCQDVFSFQVSPEMNPIKINELAIQKRLTIHGKEDE
ASPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECSKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNELLEFDINICDLPRMARLCLAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVASRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LSPRDALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLR
>A0A2K8FKR1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSAQTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARL
CFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKG
ELLNPTGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKILELGRHSECVHVTEEEQLQ
LREILERRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCS
WPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELT
KFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALS
KLKALNDFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCT
FMDSKMKPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRE
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGIN
RERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGL
PELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A7E2E0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSAQTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPCSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A2K5ZJY1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mandrillus leucophaeus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3Q2X562|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Haplochromis burtoni|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKSIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRAFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKTKNSKKIFINVKFEASDESFMLQQDPHDLPLVLMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNSQNPHLTMVHYSTVTKCQEEQGRMCNQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPCVPDEKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKVLSPKRLHKKFMDNKNYTEFFEDEKELLWKLRTEVRDHYPESLSKLLLIT
KWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLRKLSDDELLHYLI
QLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASVGLRFGLILEAYCR
GNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESYLEALSDLLSPLNP
SIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLRQDMLTLQMIQLME
NLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNW
LKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGN
FKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLF
AMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEALRESWKTKVNWMMHSL
AKDNRP
>A0A8D0Y7A7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRFGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIDML
QKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLPQSFRVPYDPGLKAGALVIEKCK
VMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDL
CLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLSHWLKEKCPIEEKFQ
AAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKER
VPFVLTPDFLFVMGTSGKKTSLHFQKFQVNGFPFDHLLGIPTRGACSPHLSLPFEAPLPC
AHLLPISSVPSPSPK
>A0A6P8PT01|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MPPGVYFPADFWAKEQNKNILIDFLLPTGIYITFSVPRNASLGNIKQSLWHHAQYEPFYH
MLSEPQAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVQKLINSHISLL
IGKGLHDFDSVGDLEVRDFRSKMRQFCEEKAAERQQLGWEAWMEYSFPLQLEPSARLLKM
GIFHINSKNIIVNIKFESSEESFTLQISAKEFPLALVRSALKKKAIVFRQQNKEEPEDYT
LKVNGCSDYIYGQYPLCQFKLSPVSLWNFEQAFCVKILQGSNVNADECLKLVVHAGLFHG
NEMLCKAVRTAEVSESSEPIWNQMMEFDIGICDLPRMSRLSFILYAVEKTKKARSTKKKS
KKADCPIAWVNTMVFDWKDMLKTGECCLYMWSSAPDDKGELLNAMGTVQSNPNTESAVAL
RICFPSISQHPVYYPPFEKILELGKAGEQQCSTVDEQQQLKELLERRGSVELYEHEKDML
WKLRHEIREQYSEALARLLLITKWNRHEDVAQMLYLLQSWPELPVLFALELLDYNFPDRC
VRAFTVNCLKKLSDEELCRYLLQLVQVLKYESYLDCELTTFLLERALANRKIGHYFFWHL
RSEIHVPAVALRFGLLLEAYCRGSHYHMKVLVKQVEALTKMKALNDIVKISSQKATKPQT
KEVMHVCLKQENYLEALLNLQSPLNPSVILGNVCVDLCTFMDSKMKPLWIMYNNEMNQNH
VGIIFKNGDDLRQDMLTLQMIHLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEIVGNSDT
IANIQLNKSNMVATAAFNKDALLNWLKSKNPGVALEQAIEEFTLSCAGYCVATYVLGIGD
RHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKPNNNEKF
ERFRNYCEKAYMVLRLHGPLFLHLFALMKAAGLPELSCSKDIQYLKVKQCSG
>A0A093QC44|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phalacrocorax carbo|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8B9WDQ4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus grunniens|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A0S7K1Y2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poeciliopsis prolifica|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLINIKQQLFIEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIMSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLENFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYR
>A0A8C0SKA6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYCFPLQLEPSARSWGP
GTLRVPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMR
QEAYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKVNARQMVAPTSPRPTSGHCGL
WSPEHGGAHRASPVWLPHATCDPTAGSGGDNLVLLHMCWDLPWATLLWLLLYKRAELVTL
PLCLKCFSSLCLFSLGEAGGS
>A0A8C0TWC3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNDFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPNDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKNI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMRSEVHIPAVSVQFGVILEAYCRGSVGHMKV
LSKQVEALNKLKTLNSLIKLNAVKLNKAKGKEAMHTCLKQNAYREALSDLQSPLNPCVIL
SELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWK
EAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEY
NSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSK
FGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALML
TAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDY
RS
>G3R1S6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gorilla gorilla gorilla|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A5A9NC53|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Triplophysa tibetana|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDVGGPHSRALYVYPPNVESTLELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIKVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDVPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKYPDMAMIEDHANWIISREMGYNYCQSGPSSRLARDHAMTDVDIEQLRQLSNRDPL
SEMTEQEKDFLWRHRQYCVNIPEVLPKILLAVKWNSRDEVAQMFCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDLAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKEDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A7L1P7Z7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oriolus oriolus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVRFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYVELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C4F585|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MDGKQIQVSDEEPRVLREENRRRRRKKAITSSSSSSMDQIAVEFVLPTTARGGNSPDTLQ
LEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRLSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQMVPRPQPSDESLQYQRYLNNLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVGNGNILVVIHIGTASQTIKVSID
DPPAQVLASFFTKTANKRALLGIPENMCEEDFVMRVCGREEYLYGDKPLQNFNWIRQCLK
NGEEIHLVLESPPDPELDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKSFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVVCGKQPQTPNSKGGSTYQDNTAVTGSHDGKTKSRLLYYVNLLLID
HRSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASTMAIAILLDKYCYPVVL
PKSRDVGRDIGAGGEEAEGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRH
ECMRDPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQV
RSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLR
SEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTRDIKAMSADKYDVT
AQVVFQLRQKLEALQLSGLPKSFRVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADP
TTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIE
IVKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATY
VLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGK
KSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRS
EDEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A3B3QLK8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Paramormyrops kingsleyae|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLNQ
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKESVDLRDANGAHSRALYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
TFTMPSYARRISTATGYMNGEASAKCLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDIYICDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMATVEEHANWTISRELGFNYCHAGLSNRLARDNALTESDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEAVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDLAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A6I9HMR7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geospiza fortis|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSSLPLPLPPKKRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLCK
TVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKYQ
TIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMERD
PLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPRE
ALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERAL
GNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSL
IKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKP
LWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATG
DHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLSC
AGYCVATYVLGIGDRHSDNIMVRKNGQLFHIHIGHILGNFKSKFGIKRERVPFILTYDFI
HVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K7ILB8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Loxia curvirostra|TrEMBL
MELGDHDQPVVMRDENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQRQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRMKIIGIDIPVLPRNTDLTVFVEANIQHGQQILSQRRTSSKPFTEEVLWNMWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A673XB88|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPAMTNLMDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQQVQLMTWSEWLQACFSPQLEPGGG
ATPVTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISA
IGAVVNRKSSIPPLPLPPKRRGPSQVNTCVWQVSTHFKIVLIKGSKVNAEETAKVQVRAG
LFHGTELLCKPAVSSESSGRSEHVWNSTLEFDITVSDLPRMTRLCFAVYAVMDKVKKQKS
TKNAHINKYQTIRKSGKVHYPVAWVNTMLFDYKGQLKTGDIILHSWSSFPDELEEMLNPI
GTIQTNPYTENTTALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCLPMGRGGKKFHI
ELKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQ
IWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCAL
TRFLLNRAQCNRNIGHFLFWHLRSEMHMPAVAVQFSLILEAYCRGSIPHIEVLKKQVEAL
SKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSG
INVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEA
NLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNS
GDALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFG
IKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTA
GLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A667XJF1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MDQQQVQVSDEEPVVLREESRRRRRKKAITPSSCASMDQITVEFVLPSAARGGSGPDTLL
LEVAANWTVEQVKAQVWLRAVASNLCPDFYQRFSPDHCILLYQKKGSVCEIYDKHQVFQT
LDCIRYWRALKKEVGRIQLVPRPQPTDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDAKLYSTDPWLTDRPLTEHLLSKVSNGHILLVIHVGSNSQTIKVSID
DTPVLASFFTKTANKKALLGIPDSVCEADFVLRVCGREEYLYGDKPVQNFHWIRQCLKNG
EEIHLVLETPPDPALDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRK
FRVKVLGIDIPSLPKNPELTVFVEASIFHGQQLLAQERTTSKPLSEEVLWNCWLEFNIRI
RDLPKGARLNLQVTAQKTQRELFSSPSSPDTKSRLLYYVNLLLVDHRSLLRQGEFILHMW
KMPEKSEESSSSVNADKLTSATNPDKASSMAVSVLLDRYCFPVVLPKSREAGRDAAAPDE
AEGGERGQREMPNHLRKQFEAIVATDPLHPLSPEDKELLWHFRHECMRHPRAYPKLLSSV
RWGKQEDVLITHRLLERSTAWDSSRLDVGLAMQLLDCHYSDAQVRSMAVRKLETLGDDDV
LRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIVQSMHYQQRYAVL
LEAYLRGCGEAMLQDFRKQVEVTEALQRVTREIKAMSADKYDVSAQVVFQLRQKLETLQS
SGLPDSFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSRDAIGIIFKDGD
DLRQDMLILQILLIMESIWETENLDLSLLPYGCISTGNRIGMIEIVKDATTIANIQQSVV
GSTGAFKDEILHQWLRDRCVSEDKKLCCVCVCVCVCVCVCVCVCVCVCAGNLFHIDFGHI
LGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFHKFQDVCVKAYLALRHHTNLLI
ILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQINWFV
HLVLGIKQGVEKRSA
>A0A8C3T233|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelydra serpentina|TrEMBL
MPPAMTDILDIWAVDSQVGADGLISVDFLLPTGTYINLDVPRDATICHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVKEFRSKMRRISEEKLLSLVGLSWLDWLKHSYPPEQEPSIPE
NFQDKLYGGNLRYLRVSVCALLDVFSFQVSPNINPVKLNELAIRKRLTIHGKEEEVDPYD
YVLQISGRLEYIFGDHPLIQFQYIRKCVMNRTLPHLTLVECCSIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRTVTVTLMFLSKYSWHVFGYFSVTPLLQVHVRAGLFHGTELLCKP
IVSAEIFGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKTINPSKYQT
IRKHYPVAWVNTMVFDFKGQLKSGDFLLHSWTSFPDELEEMLNPMGTVRTNPYTENATAL
HIKFQEYSKLPIYYPPFDKGRGGKKFYIELKEIMERDPLTQLCENEMDLIWTLRYDCREN
FPQSLPKLLLSIKWNKLEDVAQVGQMALLQIWSKLPPREALELLDFNYPDQYVREYAVGC
LKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLVERALANRRIGQMLFWHLRSEVHIPA
VSVQFGVILEAYCRGSIAHMKVLSKQVEALNKLKTLNSLIKLNAMKQSKAKGKDAMHTCL
KQNAYREALSDLQSPLNPSVILSELYVEKCKYMDSKMKPLWIVYNNKMFGGDLLGIIFKN
GDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGCLATGDHSGLIEAVSASETIADIQLN
SSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCC
EDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFD
EALRESWTTKVNWMAHTVRKDYRS
>A0A8C3RUF8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelydra serpentina|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVCPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWAINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMTVIEEHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYSVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNIFTFHLLILLFNSTISIDLFTRSCAGY
CVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVI
SKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRK
TLALDKSEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C3T151|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelydra serpentina|TrEMBL
YCSIMPPAMTDILDIWAVDSQVGADGLISVDFLLPTGTYINLDVPRDATICHIKQLLWKQ
AHSYPLFHLLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLKLVTRNCDPGEKL
DSKIGVLIGKGLHEFDALQDPEVKEFRSKMRRISEEKLLSLVGLSWLDWLKHSYPPEQEP
SIPENFQDKLYGGNLVVAIHFDKCQDVFSFQVSPNINPVKLNELAIRKRLTIHGKEEEVD
PYDYVLQISGRLEYIFGDHPLIQFQYIRKCVMNRTLPHLTLVECCSIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRTSVWDNSNPFKIMLLKGNKLNTEETAKVHVRAGLFHGTELL
CKPIVSAEIFGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKTINPSK
YQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDFLLHSWTSFPDELEEMLNPMGTVRTNPY
TENATALHIKFQEYSKLPIYYPPFDKILEKAAEIAKSSENAGMAGRGGKKFYIELKEIME
RDPLTQLCENEMDLIWTLRYDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWSKLPP
REALELLDFNYPDQYVREYAVGCLKQMRQFRSILLSPSSDEELSQYLLQLVQVLKYEPFL
DCALSRFLVERALANRRIGQMLFWHLRSEVHIPAVSVQFGVILEAYCRGSIAHMKVLSKQ
VEALNKLKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELY
VEKCKYMDSKMKPLWIVYNNKMFGGDLLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGL
DLRMLPYGCLATGDHSGLIEAVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGD
DLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIK
RERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A151N3V4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alligator mississippiensis|TrEMBL
MPGARSGSPAWDGRWSRAGQVVAKNLGTIKEVVWQHAQYEPLYHMLNDPEAYVFTCINQT
AEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHEFDSVSDPEV
SDFRTKMRQFCEERAAKRQQLSWMAWMEYSFPLQLEPLAKGLGTSPLHVSHKNIFVNVMF
ESGGESFTFQISPREYPITLMSYAIKKQATVFRHQTVESPEDYTLQVNGKCEYLYGNYPL
YQFQYIRSCLHQGLMPHLTMVRFSTIIAMRDEQTNCIAHPPKMGAKPPPLPKKKPNSGSL
WSLEQPFYIDLVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSSSEVNVCSEPVWKQRLD
FDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKAGE
CCLHMWSSFPDEKGELLNPMGTVQSNPNTESAAALVICFPNVSVHPVHYPAYEQLLDLGR
NGEHSRATLDDPEEKQQLKEILERRSHTELYEHEKDLMWKMRYHIRDQYPEALAKLLIIT
KWNKHEDVAQMISLLHTWPELPVLNALELLDFSFPDRYVGFFTINSLKKLTDEELFQYLL
QLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCR
GSTHHMKVLMKQGEALNKMKALNDFVKVSSQRATKPQTKEMMHVCMKQETYLEALSNLLS
PLNPNIILAEVCVEQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMI
QLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDA
LLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGH
FLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRDYCEKAYMILRRHGLLF
LHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWL
AHNVSKDNRQ
>A0A0P6J9T8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Heterocephalus glaber|TrEMBL
MPPGVDCPMEFWTKEENQNVVVDFLLPTGIYLNFPVSLNANLRTIKQVLWYRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDIRPFLPVLRVVAREGDRVKKLINSQISLL
IGKGLHEFDSLGDPEVNDFRAKMRQFCEEAAARRQQLGWEDWLQYSFPLQLEPSAGSWGP
STLRLPNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEDYV
LQVNGRLEYLYGSYPLCQFQYVCSCLHSGLTPHLTMVHSSSILAMRDGQGNPDPQVQKPH
PKPPPVPTKKPSSVSLWSLEQLFCIELIQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWKQRLEFDISICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANIMLFDYRDQLKTGERRLYMWPSVPDEKGELLNPAGSVHGNPNTESAAALVIFLPEVAP
HPVYYPALEKILELGRHGEQRGQGTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQ
EHFPDALARLLLVTKWHKHEDVAQMLYLLCSWPELPILSALELLDFSFPDCHVGSFAIRS
LRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPS
VALRFGLIMEAYCRGSTHHMKVLMKQGEALNKLKALNDFVKVSSQKTTKPQTKELMHLCM
RQETYLEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSKEAGTTGSVGIIFK
NGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQL
NKSNMAATAAFNKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGY
CERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKF
NEALRESWKTKVNWLAHNVSKDNRQ
>G1PAN1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myotis lucifugus|TrEMBL
MPPGVDCPMEFWANEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKALWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRKCDIQPFLPVLPLAREGDRVKKLINSQISLLIG
KGLHEFDSLRDPEENDFRVKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGAGT
LRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYTLQ
VNGKQEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKSRTK
PPPIPMKKSSGCWALGRLRHVFWLTVLTQGIKMIAVGRIKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVCSNPNTESAAALVICLPEVAP
HPVYYPALDKILELGRHGEHGRATEEEQLQLREILERRGSGSGSGELYEHEKDLVWKMRH
EVQERFPEALARLLLVTKWNRHEDVAQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFA
IKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMH
VPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPQTKELMH
LCMRQETYLEALSHLQSPLDPRILLAEVCVEQCTFMDSKMKPLWVMYSNEEAGGDGSVGI
IFKNGDGAGGTDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLRS
DTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGI
GDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSE
KFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEA
LKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C9BJD5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phocoena sinus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
AKPPPIPLKKPASVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTK
PQTKELMQLCLRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEA
GSDGTVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDHTGLIEVV
LHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYV
LGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTN
NSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTE
EEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q1GIC1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acanthochromis polyacanthus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>G1T3Z0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryctolagus cuniculus|TrEMBL
MELESSEQPVVLREDHGRRRRRMKPRSPAASLSSMELIPIEFVLPTSQRDSKTPETALLH
VAGHGNVEQMKGQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKLLHRSPGQIHVVQRHAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
LTPRMAEVASRDPRLYAMHPWVTSKPLPEYLARKITNNCIFIVIHRSTTSQTIKVSADDT
PGNILHSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIRNFQWVRQCLKNG
EEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKVRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSAKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASADTPGAESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENAMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYETLKHPKAYPKLFSSVKWGQ
QETVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDLTQQVLVIEMLQKVTIDIKSLSAEKYDVSSQVILQLKQKLENLQNSNLP
TSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTALSKETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEDKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVKAYLAL
RHHTNLLIVLFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8C7WNJ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias sinensis|TrEMBL
MDRQSIQVSDEEPEVPREECRRRRRKKAITSSSCVSMDQITIEFVMPSAARGGSGPDILT
LDVAGNWTVEQVKAQVWMKAVTLNLCPDFYQRLSPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIPYWRALKKGVGRIQMVTRPQLSEESLQYQRYLNGLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLAKVNNGHILVVIHIGTVSQTIKVSIN
DTPSQVLASFFAKTSNKRVLLGIPDDVCEADFVLRVCGREEFLYGEKPLQNFNWIRQCLK
NGEEIHLLLEKPPDPELDVVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPTLPKVPELVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKPTQTPASKGSSHHDNSAGTGSLEGKTKNRLLFYVNLLLVDH
RSLLRQGEFILHMWKMPEKSDESSSSINADKLTSATNPDKSSSMAVAILLDKYCYPVVLP
KSRDVGRDSGAGEEMEGGERGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRQEC
MRDPRAYPKLLGSVKWGKQEDVLATHRLLERSNAWDTSGLDVGLAMQLLDCHYSDSHVRS
MAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGESMLQDFRKQVEMTMALQKVTREIKAIAADKYDVSAQ
VVFQLRQKLETLQSSGLPETFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTT
LSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETECLDLCLLPYGCISTGNKIGMIEIV
KDATTIANIQQRVVGSTGAFKDEILHQWLRDKCVSEDKFQQAVERFLLSCGGYCVATYVL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKS
SPHFLKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEE
EAQRHLLDQIEICREKGWMVQVNWFVHLVLGIKQGVEKRST
>A0A452TQG7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus maritimus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKVRNPMLRVGVFL
FSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDP
LSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAM
ELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDIL
KQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C7X0E5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias sinensis|TrEMBL
MPPRPSSGELWGMHLMPPSIVVDCLLPNGMILSLECLREATLVTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILSREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDNNGPHSRALYVYPPNVESSTDLPRH
IYNKLDKGQIIVVIWVIISPSNDKQKYTLKISHDCVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPSD
NFTMPSYARRISTATSYMNGETSSKNLWTINGMLKIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLSYDMYILEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEQF
SSPVKFPDMAYVEEHANWNISRELGFNYSHTGLSNRLARDNPLTDNDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHSCINIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWIKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKEDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>Q3V1C0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|TrEMBL
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVQPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLD
CLHYWKLMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIANNCIFIVIHRGTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMNISESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
DEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFAEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPSLSSKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRHGDY
VLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSNLP
ESFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGSSGKKTSPHFQKFQDVCVRAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A2K6KMK9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinopithecus bieti|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLDVFSFQVSP
NMNPIKVNELAIQKRLTIHGKEDEVSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNR
TLPHFILVECCKIKKMYEQEMIAIEAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIV
LVKGNKLNTEETVKVHVRAGLFHGTELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPR
MARLCFAIYAVLDKVKTKKSTKNINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGD
IMLHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAA
EIASSDSANVSSRGGKKFLPVLKEILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKL
LLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELS
QYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWHLSLIKLNAVKLNRAKGKEA
MHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVG
VIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIA
DIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRH
SDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGR
FRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQF
KQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A2K6L2S0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinopithecus bieti|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVSQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKRMKHKRCVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A6P9DUE8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pantherophis guttatus|TrEMBL
MPPGMYCPPEFWSKESNYTIHVDFLLPTGIYLPLPVSCHASLAAIKKVVWHQAQYEPFFQ
MLSTPDSYVFTCINQAAELQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLLNSQISLL
IGKGLHEFDSLADPEVDDFRVQMQEYCEEKAAQRQQLSWKDWMEYSFPVQLEPSLSGLGR
RQTLPMAGKTVFVNVKFQSGGESFTFQVSLKEFPITLMSYAVKKQATIFRHQRVNPVDEY
TLQVNGKYEYIYGEHPLYQFQYIRECLHRRFVPHLIMVHRSSLLSLREEQSNGLGHPPKT
APKLSLSPKQKLTCVSLWSLEQPYSIELLHCSKVNADEGMKLVVQAGLYHGHEMLCKMMT
STEANVCSEPAWDQTLKFDIHVCDLPRMARLCLALYSVVEKAKKARSTKKKSKKADCPLA
WVNVMLFDYQDQLKTGECVLPMWSAFPDEKGELLNPTGTIQTNPNTESAATLFIRFPGIS
LYPIYYPPMRQILEKGQNGHGACGTGEDPEEKQQLKEILERRSCIELYEHEKDLVWKMRY
QIQDQYPGALAKLLMVTKWNKHEDVAQMIFLLQSWPELPVLNALELLDFNFPDPYVSRFT
VNSLKKLTDAELFQYLLQLVQVLKYQSYLDCELTKFLLGRALSNRKIGHFLFWHLRSEMH
FPSLALRFGLILEAYCRGNAHHIKALMKQSEALNKLKALNDLIKVSAQKNTKPQTKEFMH
TCMRQETYVEALSNLQSPLDPRIFLAKVSVELCTVMDSKMKPLWIMFNNGEAGGNGTGLI
FKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKMGLIEVVRNSDTIANI
QLNKSNMAATAAFNKDALLNWLKSKNPGDALERAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMVRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFR
DYCETAYMILRGHGLLFLHLFSLMKAAGLPELSCSKDIQYLKDSLALGKTDEEARKQFQL
KFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3B4WAV4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola lalandi dorsalis|TrEMBL
MPPGKYGMQEEWAKEGVREIMMDFLLPTGIFLKFPVPPNDTIKNIKKMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERQLLPWQQWMEYSFPCDLEPCCSPCGS
AKSKNTKKIFINVKFEACDESFMLQQDPQDHPGALMRSALKKKATVFRSLRQEPEDYTLQ
VNGSWEFIYGKHPLRQFKYIFSCLRNGQNPHLTMVHHSTISKYQEEQGRMCSQGYKSRSM
SRPPPLPLKKLVVQAGLFHGSELLCKVVTSSEVTVGSEPLWDQKLEFDINVADLPRMSRL
CFALYAVIEKTKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKS
DLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPLDKVLLKKKSSYLKLKEIMDNKN
YTEFFEDEKELLWKLRTDVRDHYPESLSKLLLITKWNKREDVVQMVSLLKNWPDLPAIHA
LELLDYSFPDPTVRSFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALS
NRRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDFV
KSGSQRMTAEDLKTCIKQDSYVEALSDLMSPLNPSIILAEICIDKCRFMDSKMKPLWLMY
KNHWTQGDMVGIIFKNGDDLRQDMLTLQMIQLMETLWKKEGLDLREKLDQAIEEFTLSCA
GYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVH
VIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKD
SLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A665UAH5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MSPGKYGMQEDWEKDGVQEIMMDFLLPTGILLNFPVSRNDTIKNIKRMVWKNARSEALFN
ALGDSDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNHEVNEFRSKMRTFCEEKAQERQQLSWQQWMEYSFPCDLEPCCFPCGS
AKSKNTKKIFINIKFEACDHDLLLSQESFMLQQDPQDLPEALIRNALKKKATVFRSVRQE
PGDYTLRCNGTWEFIYGNHPLCQFKVSSHKTPSLVKCPTFTDQYDQQHMYNKNPPQPTNQ
NTSSLWSINEPFYIHLVQGNRVNADEGMKVWCGFAGLFHGSELLCKVVTSSEVTVCSEPL
WDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKAVSLAVTYGIFRPSCTT
HRDCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLL
IHFPNIRQYPLYYPPLDKICDLEKNGDTHISFFSGTKEEYLKLKEIMDNKNYTEFFEDEK
ELLWKLRADVREYYPESLSKLLLITKWNKREDVVQMVSLLRNWPDLPVIQALELLDYSFP
DPAVRSFTVRCLRKLSDDEILQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLF
WHLRSETHVASVSLRFGLILEAYCRGNIHHIKLLAKQNEALGKMKALSDFVKSGSQKMTA
EDLKLCIRQESYLEALSDLLSPLNPSIILEEICADKCRFMDSKMRPIWLMYKNQWAQGDM
MGIIFKNGDDLRQDMLTLQMIQLMETLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDT
IANIQRNNSNSAATAAFNKDALLNWLKSKNPEEKLDQAIEEFTLSCAGYCVATYVLGIGD
RHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTSNSEKF
ERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALK
NFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A665U9L0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MSPGKYGMQEDWEKDGVQEIMMDFLLPTGILLNFPVSRNDTIKNIKRMVWKNARSEALFN
ALGDSDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNHEVNEFRSKMRTFCEEKAQERQQLSWQQWMEYSFPCDLEPCCFPCGS
AKSKNTKKIFINIKFEACDSFMLQQDPQDLPEALIRNALKKKATVFRSVRQEPGDYTLRC
NGTWEFIYGNHPLCQFKVSSHKTPSLVKCPTFTDQYDQQHMYNKNPPQPTNQNTSSLWSI
NEPFYIHLVQGNRVNADEGMKLVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQRLEFDI
NVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLL
STWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIHFPNIRQYPLYYPPLDKYLKLKEIMD
NKNYTEFFEDEKELLWKLRADVREYYPESLSKLLLITKWNKREDVVQMVSLLRNWPDLPV
IQALELLDYSFPDPAVRSFTVRCLRKLSDDEILQYLIQLVQVLKYESYLDCDLTTFLLER
ALSNRRIGHFLFWHLRSETHVASVSLRFGLILEAYCRGNIHHIKLLAKQNEALGKMKALS
DFVKSGSQKMTAEDLKLCIRQESYLEALSDLLSPLNPSIILEEIWLVRTHKCRFMDSKMR
PIWLMYKNQWAQGDMMGIIFKNGDDLRQDMLTLQMIQLMETLWKKEGLDLRMIPYGCLST
GNKMGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEEKLDQAIEEFTLS
CAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDF
VHVIQQGRTSNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYL
KDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A1S3GVM2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dipodomys ordii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7L1GHB9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Indicator maculatus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEIILLE
IAGNCTVEQMKAQIWMRAIEMSQVTDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNSIFIIIHRGTTSQKIKVSIDDT
PEMILQSFFTKMAKKKSLMDIPEDHSEMDFVLRICGRDEYITGETRIKDFQWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVVWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNILLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPVALPKHRITSD
SQGDRTRVEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEIWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTCQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILTQWLKEKCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSVHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C5A5C1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MPPGNYGMEEEWEAEGNADIMVDFLLPTGIFLEFPVSRNDTIADIKKLVWRRASSEPLFN
ALGDPASYVFVCISSAAERLELEAEHRRLADVRPFACFLQLVAREGDRAEKLANAQISLL
IGKGINEFEAQKNHEVSEFRARLRAFCEEKALQQQALPWFQWMECNFPCDLEPCRALPSR
GGGAKAPKKIFINIQFEGSDESFMLQQDPQEPPLALIRSALKKKATVFRWVRQEAEDYTL
RVNGRWDFLYGDHPMCQFKYIFSCLRDGQNPQLTMVYHSTIRAYQEDQGSAWRQGSKSST
SASKPPPLPLKKVGRRGGLCLSLEPLCIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKL
VTSSEVAVGSDPVWNQRLEFDINVADLPRMSRLCIALYAVVEKAKKPRGTKKKSKRADCP
IAWVNTMVFDYKDQLKTGEFLLSMWPSIPDDKSELLNPMGTVEKNTNVDSAAALLIHFPS
VRPQPLYYPPHDKVTGGGGSRHVRLKEIMDNKNHTEFFEDEKELLWKLRGAVQSLYPESL
SKLLVITKWNKREDVAQMVGLLRAWPELSGLHALELLDYSFPDPSVRAFTVKCLKKLGDR
ELMQYLIQLVQVLKYESYLDCDLTSFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGL
ILEAYCRGNIHHIRSLTKQNEALGKLKALSDIVKSGSQKMSADDLKLCIKQDSYMEALSD
LLSPLNPSIILSEICVEKCKYMDSKMKPLWLMYKNQWVPGDLMGIIFKNGDDLRQDMLTL
QMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRDNSNSAATAAFN
KDALLNWLKSKNPEHKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHID
FGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRDYCERAYKILCRNG
TLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKTEEEALKSFKVKFNEALRESWKTKV
NWMMHSLAKDKRP
>A0A8C5CAP7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MPPAMTDILDMWSPLAGHATELVPVDFLLPTGIYIQLEVPSEATIQHIKLLLWKQAQTYP
LFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLRLVTRNCGRAERLLDSKI
GVLIGKGLHELDALQAQEVKDFRAKMLRVSEARMQFYHAMTWSEWLQACFSPQMETTGAA
PPAASSYSQEDYLKITIHFDQSQDAASLRVSPAFTPTEVMEQGLKKWLTTHGPEDDSRQG
PYVLRVSQRLEFLCGDHPLIQYKYIKECIQAREPPHLTLVLTSTIRTMFEKEISAIGAVV
SRKSSNPPVPLPPKRRAPTVSLLQTCVWDVSSQFKIILLKASKVNAEETAKVQVRAGLFH
GTELLCKPAVSSESSGRSEHAWSDGTLEFDIVASDLPRMTRLCFAVYAIMDKVKKQKSTK
NTHSNKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDVILHSWSSFPDELEEMLNPIGT
IQTNPYTENATELHVHFQEYSSQPIVFPPFDKILEKAAEIAKANDLVPMGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRHDCHLKFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PRLSPRDALELLDFNYPDQYVREYAVRCLREMSDEELSQYLLQLVQVLRYEPYYDCALTR
FLLERAQANRKIGHFLFWHLRSEIHMPAVSIQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKTARSKTKEAMLTKEAMMTCLRQSGYSETLSDLNSPLNPSIQLSGIN
VERCRYMDSKMKPLWIVYHNKLLRGDSLGIIFKNGDDLRQDMLTLQILRLMDLLWKENSL
DLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEDAYLILRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A674GZN2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGV
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGRTPHLTMVHSSAIIAMRDEQTNGITSPPKAA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEELREILERRSHTELYEHEKDLVWKMRYDIRD
QYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAVNSL
KKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPAV
ALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCMK
QETYREALSHLQNPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNG
DDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNK
SNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMV
RETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCE
RAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A674H6E3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGV
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGRTPHLTMVHSSAIIAMRDEQTNGITSPPKAA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEELQLREILERRSHTELYEHEKDLVWKMRYDI
RDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAVN
SLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVP
AVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMC
MKQETYREALSHLQNPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFK
NGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQL
NKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGY
CERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKF
NEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L0D663|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rostratula benghalensis|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLFQFQYIRSCLHRGLTPHLTMVHCSTIIAMRDEQTNCIASPPKVA
AKPPPLPKKKPNYGSLWSLEQPFHIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAL
HPVYYPSFEQLLELGRNGDQSRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNDETGRGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRS
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A669QZD4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phasianus colchicus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINSIANPPKMA
VKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALLICFPNVAS
HPVYYPSFEQLLELGRNGEQPRSQKLQLKEILERRSHTELYEHEKDLVWKMRHDIRDQYP
QALAKLLTITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAINSLKKL
TDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALR
FGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQET
YLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDL
RQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNM
AATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRET
GQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAY
MILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALR
ESWKTKVNWLAHNVSKDNRQ
>A0A669QWP9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phasianus colchicus|TrEMBL
FCFMSRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQ
YEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLIN
SQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPM
AKGLGTGLLHTPTKNIFVNVKFQSGGVNFTFQISPNEFPITLMSYAVKKQATVFRHETME
NPEDYTLQVNGKYEYLYGNYPLYQFQVSLLSCFDKRKSPNYGSLWSLEQSFYIELVQGSK
VNADERMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCF
ALYAVIEKAKKARSTKKKSKKAVSKDCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEK
GELLNPMGTVQCNPNTESAAALLICFPNVASHPVYYPSFEQVGNTDSLASKLQLKEILER
RSHTELYEHEKDLVWKMRHDIRDQYPQALAKLLTITKWNKHEDVAQMISLLQSWPELPVL
NALELLDFSFPDRYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRA
LSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNE
FVKLSSPKATKPQAKEMMHVCMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMK
PLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLST
GDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDF
VHVIQQGKTNNSEKFERFRGYCEKAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYL
KDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C1J9U2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVAQS
GKSRSVKKILVNVKFEGSEETFVLQQDPQDLPMLLKRNALRKKSTVFRAAKQEKPEDYTL
QVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQMSRTRA
PSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVI
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGMNGEKVVTTKEEMVGLLRKWPELPAIHALELLDYSFPDPHVRSFT
IRCLRNLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRSEMH
VPSVSLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMK
VCIKQDTYMEALSDVVSPLNPSIVLCELCTDKCKFMDSKMKPLWLMYKNKYDHVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRN
NSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECC
EQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIHGWNFSLE
>A0A1A8RFX8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius rachovii|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREAALNTIKHELFKEVRKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDSSGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYTQLPTD
SFVMPSYSRRISTATSYMNGEAASKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSVCSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVASKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNFPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFW
>A0A8C2VMN9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chinchilla lanigera|TrEMBL
MAPGVDCPMECWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRVVAREGDRVKKLINSQISLL
IGKGLHDFDSLRDPEVNDFRAKMRQFCEEAAVRRQQLGWEAWLQYSFPLQLEPSARSGGP
GAPLIPNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGRHEYLYGSYPLCQFQYICSCLHNGLTPHLTMVHSSSILAMRDEQGDPAPQVQKPR
PKPPPIPSKKPSSMSLWALEQPFCIELIQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANIMLFDYRDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVICLPEVAA
HPVYYPALDKILELGRHGEQRGHITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQ
EHFPEALARLLLVTKWHKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKS
LRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPS
VALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCM
RQETYLEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSTGSVGIIFK
NGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQL
NKSNMAATAAFNKDALLNWLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGY
CERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKF
NEALRESWKTKVNWLAHNVSKDNRQ
>A0A1A8AG66|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius furzeri|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLDCLRETPLISIKQQLFVEARKFPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDSEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKTRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIVVGRLPHLMLVSKDSLYSQLPAS
GYITPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYINVNIRDIDKIYVRT
GIYHGGEPMCDNVNTQRVPCSHPRWNEWLTYDLYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYSYCHGLSSRLACDSTVSASDAEQLRSLCSKDP
LYELSEQEKDFLWRHRHYCINIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMESESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKVQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEGYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQTFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A087QQL2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aptenodytes forsteri|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRSCVMNRTLPQLTLVECCTIKKMCEQEMIAVEA
AINRKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEILEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEI
MERDPLSQLCENEMDLIWTLRYDCRESFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A668VX94|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
GNSKSQVPREESRRRRRKKAITSSCSNSMDQITVEFVLPTAARGGSGSDTLQLDVAGNWT
VEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDCIRYWR
ALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPRRI
ELSERDPKLYSMDPWVTCKPLPEHLLSKINNGHILVVIHIGTASQTIKVSIDDTPTLVLV
SFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLKNGEEIHLV
LEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVL
GIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNIKIKDLPKG
ARLNLQVICGKQPQIPNSKGSSYQESTAGSSSLDGKSRLLYYVNLLLIDHRSLLRQGEFI
LHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDWA
VGGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHECMRVPRAYPK
LLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETL
EDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSKHYQQ
RYAVLLEAYLRGCGENMLQDFRKQVDMTEALQKVTREIKTMSADKYDVTPQVVFQLRQKL
ENLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADSTTLSKDPIGII
FKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIANI
QQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDN
IMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQD
VCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQ
IEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A2K5JME1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Colobus angolensis palliatus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNSPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAIYAVLDKVKTKKSTKNI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIMLHSWSSFPGKIYILILKPKFIF
FNFFKQIIEKAAEIASSDSANVSSRGGKKFLPVLKEILDRDPLSQLCENEMDLIWTLRQD
CREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLAPREALELLDFNYPDQYVREYAV
GCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEVHI
PAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHT
CLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIF
KNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQ
LNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDN
IMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQ
CCEDAYLILRRHGNLFITLFALMLTAGLPELTSDKDIQYLKDSLALGKSEEEALKQFKQK
FDEALRESWTTKVNWMAHTVRKDYRS
>A0A8D0D775|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLLSIKQQLFTEARKYPLYH
LLQEESSYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNLESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPARSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLAYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDGEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMLKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELKTLALE
KSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>C3YMZ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Branchiostoma floridae|TrEMBL
MPPSSGELWGMHLMPPKVPVDCLLPTGIMITLDVPREATLEHIKGDLWREARKYPLFHKL
QDETMYIFISITQEAEKEEFYDETRRFCDLRLFQPWLKVTEPRGNREEKILNSEISLAIS
MPVTEFGTVKDPEVIDFRRNILTTCLQSVQERDQDGQSGQSLYVYPPIIETDPSLPKNLD
AKLDIGHIIVTIWVLTRENERQKYTVKVSKSSLPEDVIAGAIKKKTRTMGLTPEQQQQCI
EGYQSSYVLKVCGAEEYMLGRYPIIQYKYIRMCLSRSRFPNLMLMSKEGVYASLPESTFH
LPSYARRGSSAVLNPSNGTAQIRCIYDIQSPLRIKILCATYVNVKEHDKIYVRSGVYHGG
EPLCTPVNTNRVQCSNPLWTEWLEYEIMIPDIPRSARLCLSICSVNRKKGKKEDHCCLAW
GNINLFDYQGNLQNGKYQLNMWSVPHGMDDLLNPIGSTGSNPSKDTPCLDLEFDRFAHVV
KYPDDQQIEEYAKWIANVNSEGNILRGTTSSASNVSLHSRGKYLELEQLNEILRKDPLSD
FSEQEKDLVWKMRKRCQEIQDSLPRLLQSCKWSSREDVSQMYMLLENWPQVSPETALELL
DCTYADLKVRNFAVDCLRKTMTDDQLSQYLLQLVQVLKYEPYLDNPLARVLLERSLLNQR
IGHFFFWHLKAEMSNKNVRIRFGLLLEAYCRACGAYLKSLVRQVEAQEKLTMLTETLQER
EREKKDTTQRERLKFLGEKINQEDYLEALQNFPCPLNPSHLLGKLLIKECKVMKSAKRPL
WLNWENPDPMADLYFLNQMIIFKNGDDLRQDMLTIQMIRIMDNIWQTEGLDLRMLPYQCL
SAGNCVGMIEVVRNAKTVMQIQRMSGITGTLQLRSDSLHEWIKSKNKGDRYDRAIEAFTL
SCAGYCVATFILGIGDRHNDNIMVNEEGQIFHIDFGHFLGHFKKKFGYKRERVPFVLTED
FLKVIARGGDYQKSKEFKSFQELCGRAYLYLRKHANLFIVLFTMMLSTGIPELQSFDDIE
YLRKTLAVEMTDTEALQYFSSCFNEAYSRSYSTKVDWMFHGIKQSR
>A0A3P9C6Q7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Maylandia zebra|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKSIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRAFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKTKNIKKIFINVKFEASDESFMLQQDPHDLPLVLMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTVTKCQEEQGRMCNQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPCVPDEKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKICDMERNGDLSLATKDEYFKLKEFMDNKNYTEFFEDEKELLWKLRTEVRD
HYPESLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCL
RKLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASV
GLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESY
LEALSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLR
QDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSA
ATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYK
ILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDNRP
>A0A6P7HZM2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Parambassis ranga|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWIISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A4W3K913|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPAMTDPLDIWAVDSQIPADNSITVDFLLPTGIYIQLDVPREATIDQIKMLLWRQAQTY
PLYTVLGEKDSYMFQCVNQSAVHEELEDESRRLCDVRPFLPVLKLVARNCNRSERLLDSK
IGVLIGKGLHEFDALTDPEVREFRSKMRMFNEEKMLKLQGLSWMDWLKHSFPPELESTAF
NNFEDNNSRGWVKFFCRSVISPNLNPLDLNELAIRKQLTIHGKENEEFNPRDFVLRVSGK
QEYLFGEQPLIQFRYIRNCVLKGSNPQLTLVDCCTIKEMCDREMSAIGVALHRKISNAPL
PLPPKRRTISQMATNVWDINSPFKMLLIRGNKINADEAVQVRAGIFHGTELLSKSVVSTE
VSGKNDLVWNEILDFEINLCDLPRMSRLCFAVYGVMDKVKKQKSTKNASKYQTIRKAGKV
HYPIAWVNTMVFDFRAQLKSGDLDLHCWSSFPDEMEDMLNPMGTVQTNPYSENAASLHIQ
FQEYSKSVIYYPAFDKILEKAAEIARSNDTLSMSGRGGKKLHIELKEIMERDPLSQLCEN
EMDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDVAQLQALLQIWIKLCPRDALELLDFN
YPDQYVREYAVKCLKEMSDEELSQYLLQLVQVLKYEPYFDCALSRFLLERAQANRRIGHF
LFWHLRSEMHLPATSLQFGLILESYCRGSFTHIKELSKQMEALSKLKAINNLVKLSYLKV
TRTKVKEVMNTCLKQPVYTEALSDLQSPLNPSVILSKLNVDKCKFMDSKMKPLWILYNNK
MSGGEPVGIIFKNGDDLRQDMLALQILRLMDMLWKEAGLDLRIVPYGCLATGDKSGLIEV
VSASETIANIQLTNSNVAATAAFNKDALLNWLKEKNTGDALDRAIEEFTLSCAGYCVATY
VLGIGDRHSDNIMVRETGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKP
GNAEKFGRFRQCCEEAYLILRKNGNLFITLFALMLTAGLPELSSVKDIQYLKDSLALGKS
DDEALKQFRQKFDEALRESWTTKVNWMAHIVAKDNRS
>A0A6P3VSA5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Clupea harengus|TrEMBL
MEQQFSDDESPVVRREDTKRRRRKMKAFTSNAAVAMDQIAVEFVLPTTNKSSKSPDTLHL
EVAGNCTVEQVKAQVWLRAVASHICPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQTL
DCIRYWKALKKDSGKIHLAKRPLPSDESIQYQKYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELADRDAKLYSMDPWVTTKPLPEYLMGKISNSNVLLVIHRNTSSQTIKVSIDD
TTVQVLQSFFTKIAKKRALFNIPEDVSEADYVLRVCGREEYIFGNYAIKDFHWVRQCLKD
GDEIHLVLEMPPDPDSEEVHKEDWAQVDDCTGVAGTHEQLTIDEKDHEKVFTISLWDCNR
KFRVKVLGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTPKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQSSKSSNLDNGGYDGKSKSRLLYYVNLLLIDHRSLLRQG
EFILHMWKIPDKSEDNSSVNADKLTSATNPDKTSSMAVAILLDKYCYPVALPKCRESKEA
SDLEGERGQRDMPNHLRKQFEQIVATDPLHPLSPEDKELLWHFRQECMRHPRAYPKFLGS
VKWGKQEAVMATHQLLERTTTWDRSSLDVGLAMQLLDCNFSDANVRSMAVRKLETLDEDV
VLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAV
ILEAYLRGCGDAMLQDFKKQVEITEALQKVTREIKAVSAEKYDVSAQVVFQLRQKLESLQ
VSGLPQSFKVPYDPGLRAGGLVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDG
DDLRQDMLILQILLIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDARTIANIQQSI
VGNTGAFKDELLNQWLREKCVCEDKFQQTVERFVYSCAGYCVATYVLGIGDRHNDNIMIT
ETGNLFHIDFGHILGNYKSFMGISKERVPFVLTPDFLYVMGTTGKKSSPYFQKFQDTCVK
AYSALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEEEAQRHFLDQIEIC
RDKGWTVQFNWFLHLVLGIKQGVEKRSA
>A0A8B7JQL0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Apteryx mantelli mantelli|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHTY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEERIQSLVGLSWMDWLKHTYPPEQEPVIQE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRTATNVWDICNPFKIILLKGYKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGGSDHVWNEILEFEINVCDLPRMARLCFAVYAVMDKVKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELILHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLPPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCKYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQCCEDAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C6WX38|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neogobius melanostomus|TrEMBL
MAKLLIQPFLCFLFALFSALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLV
AREGDRVEKLTNAQISLLIGKGLHEFEAQKNHEVNEFRTKMRAFCEEKALERQLLPWRLW
MEYSFPCDLEPCCSPHEEGNNKKKNTKIFVNIKFEASEVSGFSLGCYSGILSHEPQASSL
TFQHYLFDKEQLCFPEDYTLQVNGRWDFIYGDHPLCQFKVSLTFFKTVIYHNSVSYCAAL
NGINYSIMTLTYLLNCCLNISLVFCLQQNTSSLWSINEPFYIQLLHGSRVNADEGMKLVV
QAGLFHGSELLCKVVTSSEVTVRSEPLWDQKLEFDISVSDLPRMSRLCFALYAVIEKTKK
PRGTKKKNKRADCPIAWVNTMVFDYKDQLKTGEFLLSAWPSVPDDKSDLLNPMGTVEKNP
NVDSAAGLLIRFPNIRPHPLYYPPLDKKADVEKNGDASAVSKDEVNVSSNCLLRLKEIMD
NKNYTEFFEDEKELLWKLRYEVRERYPESLSKLLLITKWNKREEVVLVLLRNWPDLPAIQ
ALELLDYSFPDPSVRSFTIRCLKKLSDPELLQCLIQLVQVLKYESYLDCDLTTFLLERAL
SNQRIGHFLFWHLRSEIHVSSVGLRFGLILEAYCRGNIHHIKLLTKQNEALTKMKALSDI
VKSGSHKMTVDDLKLCIRQESYMEALSDLLSPLNPSIILTQICADKCRFMDSKMKPLWMM
YRNPCFQGEMVGIIFKNGDDLRQDMLTLQMIHLMENLWKKEGLDLRMIPYGCLSTGNKMG
LIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPGDRLEQAIEEFTLSCAGYC
VATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQ
QGRTNNSEKFERFREYCEWAYKILCHNGILFVNLFAMMKAAGLPELTSSKDIQYLKDSLA
LGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A7L4H953|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podargus strigoides|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTSTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMVSLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A091EBU2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fukomys damarensis|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSILVDFLLPTGIYIQLEVPREATISSIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEEKIQSLVGLSWIDWLKQTYPPEH
DPSILENMEDKLYGGKLIVAVHFENSQDVFSFHVSPNMNPIKINELAIQKRLTIHGKEDE
ASPGDYVLQVIGRVEYVFGDHPLIQFQYIRNCVVNRALPHFVLVECCKIKKMYEQEMIAI
EAAINWNSSNFPLPLPPKKTRIISHVWDNNNPFQVVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHTWNEALEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVKQNYLLVLDELEEMLNPMGTVQTNPYTENATALYIKFPENKKQPYY
YPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQD
CRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAV
GCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSDEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7F8K7E6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Delphinapterus leucas|TrEMBL
MLWKQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCD
PGEKLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKQTYP
PEHEPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGK
EDEVSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEM
IAIEAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGL
FHGTELLCKTVVSSEISGKNDHIWNEPLEFDISTCDLPRMARLCFAVYAVLDKVKTKKST
KTINPSKYQTIRKSGKVDYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMG
TVQTNPYTENATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAV
LKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQI
WPKLPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALS
RFLLERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALN
KLKTLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYIEKCK
YMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRML
PYGCLATGDHSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRA
IEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVP
FILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTS
VKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A1S3SFT5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo salar|TrEMBL
MEQQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKHLPEYLLSKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPEDVCEGDYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFN
IRIRDLPKGARLSLQVSCGKAQTQISKGTSSYQDNGGSPVGGGSSSHDGNKTKSRLLYYV
NLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYC
YPVALPKSREGKEAGGEGREAEGGERGQREMPNHLRKQFESIVETDPLHPLSQEDKELLW
HFREECMRHPRAYPKLLGSVRWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYS
DAHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLF
WFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEK
YDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFK
RADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKI
GMIEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYC
VATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMG
TSGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALT
VGRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGGDKRSA
>A0A1W7RF17|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Agkistrodon contortrix contortrix|TrEMBL
MPPAMADILDIWAVDSHIAADSSISVDCLLPTGIYISLDVPRDATICYIKQLLWKQAHSY
PLFHLLLEIDSYMFSCVNQTAVREELEDETRRLCDIRPFLPVLQLITRSCDPGEKLDSKI
GVLIGKGLHEFDALQDPEIKEFRIKMRQISEEKMQSLMGLSSMNWLKHTYPPELGPAIQD
NFQDKLYGGNIVVAVHYENSQDVFSFQVSPNINPIKLNEMAIRKWLTIHGKEDEVDPYDY
VLQVNGRLEYVFGDHPLIQFQYIHRCVINRALPQLTLIECGTIKTMYEQEMIAIETAVNR
KSNNLPLPLPPKKSRVTQSVWEIGQPFKILLVNGSKLDAEETAKVHIRAGLFHGNELLCK
PIVSSEIAGRNDHVWNEPLEFDINVCDLPRMARLCFVVYAVMDKMKNKKSAKALNPSKYQ
TMRKAGKVHYPVAWVNTMVFDFKGQLKTGDLLLHSWSSFPDELEEMLNPMGTVQTNPYTE
NATTLQIRFQEYSKCPIYYPPFDKILEKAAEIARNSDCSGMAGRGGKKFFIELKEIMERD
PLSQLCENEIDLIWTLRFDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPRE
ALELLDFNYPDQYVREYAVGCLRQMSDEELAQYLLQLVQVLKYEAFLDCALSRFLLEKAL
ANRRIGQMLFWHLRSEMHISAVSLQFGVILEAYCRGSITHMKVLSKQVEALNKMKTLNSL
IKLNAMKQSKAKGKDAMHTCLKQRAYKEALSHLQSPLNPSVLLSELCIEKCKYMDSKMKP
LWIVYSNKAFGGDLVGIIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRLLPYGCLATG
DYSGLIEVVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNTGEDLDQAIEAFTLSC
AGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFI
HVIQQGKTGNTEKFGRFRQYCEEAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKSDEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A1S3A2N0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Erinaceus europaeus|TrEMBL
MELEKYDQPVVLREDNCRRRRRMKPRSSTAGLSSMELIPIEFVLPTSQRNSKTPETALLY
VAGHGNVEQMKAQVWLRALETSVAADFYHRFGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLSYWKLLHRSQGQIHVVQRHAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPAYLSKKISNNCIFIIIHRSTTSQTIKVGPDDT
PTTILQSFFTKMAKKKSLMDIPESLNELDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHDSVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQKRTSSKPFTEEVLWNVWLEFNIKI
KDLPKGALLNLQIYCGKAPPLSGKAETPNSESKGKAQLLYYVNLLLIDHRFLLRHGEYVL
HMWQISGKAEDQGSFNADKLTSATNPDKDNSMSISILLDNYCHPIALPKHRPTTDPEGDR
VRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQE
IVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQ
LVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFSVILEAYLR
GCGTAMLQDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQTSNIPQS
FRVPYDPGLKAGGLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDM
LILQILRIMETIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAF
KDEVLNHWLKEKCPIDEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFH
IDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRH
HTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTV
QFNWFLHLVLGIKQGEKHSA
>A0A8C9L964|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pavo cristatus|TrEMBL
VLISLLWKQAHTYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVT
RNCDPGEKLDSKIGVLIGKGLHEFDALQDPEVNDFRSKMRRISEEKIQSLVGLSWMDWLK
HTYPPEQEPVVPENFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLT
IHGKEDEEIDPADYVLQVSGRLEYVFGDHPLIQFQYIHNCVMNRTLPQLTLVECCTIKKM
CEQEMIAIEVAINRKSSNLPLPLPPKKTRATTVITNKFEQLLLIVILLKIYPSWISSLKC
NKNGSFHETFNKCFNGLLYQIVFLSSYFNCNLIVFFLKQLQALLQIWPKLLPREALELLD
FNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIG
QMLFWHLRSEIHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAM
KQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCKYMDSKMKPLWIVYN
NKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLATGDHSGLI
EAVSGSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRATEEFTLSCAGYCVA
TYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQG
KTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALG
KSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A4W4HIW0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MPPGVCYGMQDVWEKGGREQVTLEFLLPTGIYLSFPVARNDTIGTIKKMVWKNARSEPLF
SVLSDPDAYVFTCINLTAEREELEDESRRLCDVRPFMPVLRLVAREGDRVEKLINTQISL
LIGKGLHEFDTQKNHEVNEFRAKMRSFCEENAQDRQRLPWHQWMKCNFPCDLEPFSMVVQ
SGKSCSVKKLLVNVKFEASEESFMLQLDPQDFPVVLMQNALRKKATVFRPLKQEKPENYT
LQVNGRWQFIYGNSPLCQFKYIFSCLYGGIKPHLTMVHHSTIIKYQEEQGGLSNQVSKSR
SLSKPPPLPLKKQNTSSLWSIKEPFFIQLVHGTRVNTDEGMKLVVQAGLFHGGELLCKVV
TSSEVSVCSDPVWDQKLVFDINLCDLPRMSRLCFTLYGVLEKTKKQRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSAPDDKGDLLNPMGTVERNPNIDSTAGLLIRFPSF
RPHPLYYPPLEKLNDPEINGEKVVATKEEHLKLKEIVDNKNHTEFFEHEKELLWKLRLDV
RAHYPESLSKLLLITKWNKHEDVAQVRTQMVCLLRTWRDLPPLHALELLDYTFPDPHVRS
FTIRCLKKLGDEELFQYLLQLVQVLKYESYLDCDLTTFLLERALSNKKIGHFLFWHLRSE
MHVASVSLRFGLILEAYCRGSIYHIKSLMKQIEALNKMKALNDFVKSGSQKSASRLQITE
DMKLCIKQDTYMEALSDVISPLSPSIVLSEICPDRCKFMDSKMKPLWLMYKNKWDHLDTV
GIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMVPYGCLSTGNKTGLIEVVKNADTI
ANIQRNSSNNAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDR
HSDNIMIRENGQLFHIDFGHFLGNFKAKFGINRERVPFILTYDFVHVIQQGRTNNSEKFE
RFRECCEQAYKILCRNGTLFVNLFALMRAAGLPELSCSKDIQYLKDSLALGRSEEEALKN
FKVKFNEALRESWKTKVNWMMHTVAKDNR
>A0A6P7M6J5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Betta splendens|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQSKYILKVCGCDEYLLEKYPISQYKYIRSCMMLGRLPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHSNWTISREMGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRYRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNALHQWLKDKNKGEMYDSAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8D1MMF6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFH
IDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRH
HTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTV
QFNWFLHLVLGIKQGEKHSA
>A0A341BV14|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neophocaena asiaeorientalis asiaeorientalis|TrEMBL
MPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKQTYPPEHEPSIPE
NLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDEVSPYDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAIEAAINR
NSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TVVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKAINPSKYQ
TIRKSGKVDYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALA
NRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLKTLNSLI
KLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYIEKCKYMDSKMKPL
WLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGD
HSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCA
GYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A2Y9G8Q1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neomonachus schauinslandi|TrEMBL
MCFSFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECFKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
HPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDTILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVDCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6P6J9K8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carassius auratus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLHH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQEFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSADLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKIAHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDEYFLEKHPLSQYKYIRSCITLGRLPHLMLVSKDSLYSQLPSS
GFMAPSYSRRTPQPSPCPGGADPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDEQQIEEHANWSISRELGYSYCLGLSSRLACDSSISQVDAEQLRTLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQIYCLLKDWPLMQPESAL
ELLDCNFPDPMVREFALRCLIQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIREKNKGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKNQQDALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A8C1NIF9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVI
SNEVSVCSEPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLWLAEHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLI
TKWNKHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLSDDELFQYL
LQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYC
RGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVV
SPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQDMLTLQMIQL
MDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALL
NWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMISETGQLFHIDFGHFL
GNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVN
LFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMH
TFAKDNR
>A0A2K5CF92|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aotus nancymaae|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGTIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDGLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIILVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEVSGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKAKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYIENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A1A8AFJ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius furzeri|TrEMBL
MDRQQIQVSDEECEVPREEIRRRRRKKAITSSSSISMDQITVEFVLPSAARGGSSSDSLQ
LEVAGNWTVEQVKAQLWMKAVTLNFCPDFFQRLSPDHCILLYQKKGTICEIYDKHQVFQT
LDCIRYWRALKKEVGRIQLVPRPQPTDESLQYQRYLNHLIGYDVTDVSNVHDDELEFTRR
KLLTPRRVELSDRDPKLYSMDPWVTHKQLPEHLLTKVNNGYILVVIHVSTSSQTIKVSID
DTPSQVLTSFFAKTQNKRVLLGIPDNMCESDFVLRVCGREEYLYGEKPLQDFNWIRQCLK
GGEEIHLVLETPPDPELDMVQKEDWAQVDDCTGVTGTHEQLTITEKDHERVFTISMWDCN
RKFRMKVLGIDIPTLPKVPDFTVFVEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGTRLNLQVICGKQPQMSSSRGGSYYEATSGTCCPEGKTKNRVLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAVAISLDKYCYPVVLP
KSRDVGRDCGAMGEESEGGERGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRHE
CMRHPRAYPKLLGSVRWGKQEDVLSTHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVR
SIAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTREVKTMSADKCDITA
QVVFQLRQKLETLQLSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPT
TLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLFVMGTSGKK
SSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSE
DEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>B7Q6K8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ixodes scapularis|TrEMBL
MLWFLCARTLQMQALLQIWKLLKPEQALELLDYSYPDNYVRSFAVRCLRQMSDEELSLYL
LQLVQALKHESFLDCDLVKFLLERALKNRHIGHQMFWLLRCEMQVAALSVKFGLILEAYC
HGAPDHREALLKQAEALFKLRALGNQIHESSKKKDSREKMVATMREHMSKEAFRATFRNL
CSPLDPCHVFSQIKPELCRFMDSKMKPLWLVFENSDAVAEDIAIIFKHGDDLRQDMLTLQ
MIRIMDKLWKDEGYDFRMIPYQCLSTDQNVGLIEVVRNASTIANIQKLHNSSATSAFKKG
SLFAWIKEHNKTQESLRRAVENFTLSCAGYCVATYVLGVADRHSDNIMIKANGELFHIDY
GHILGKFKEKFGIKRERVPFVLTHDFVHVITHGHRRKATAFNRFQEYCERAFLILRRQGS
LMISLFAMMLTTGMPELTSEKDLDYLRDALVLDYSEADALAHFRAKFEEALNNSWTTSIN
WFAHNISKDNK
>A0A6J8CQF4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mytilus coruscus|TrEMBL
MPPSSGELWGHHLMPSTIQVDCLLPTGIIIQVDVSRDETLERIKADLWVKAKLYPLYERL
LEPASYIFVSITQDARKEEFYDETRRFCDLRLFQPILKIVEPVGNREEKMLNFEIGVTIG
VSINEFNEMKDLEVMTFRRNILDICKNAIEDRQRRGKASEALYAYPPDIESSPILPSHLQ
TKIKEMKNDVVACVWVVSEDNSRSKFSVKVPHDAYPIDVIAGTIRRRSRMMGISKEHAER
CIEEYSDTYALKVCGCDQFLLEEHPLSQYKFLLEEHPLSQYKYVRECIARDNIPQFMLLT
KESLYAAISPNVFITPSYTQKGMQLLTEINQQKTLSLWEIHAKLRIKILCATYVNVKELG
KIYVKAGIYHGTEALCEFQDTKLVDSNNPQWHEWLEFLYIQDLPRSAKLCLSICYTSKKR
REPLSLGWANLQLFDFNDRLMNEKVSLNLWPLPQGMDDLLNYVGLPGSNPDQETPCLEIE
FDRLSHPVSYPPEKQIEDLALYAIGKESPLIYLDTPQIQTKERAMVDDITSRDPLSEISE
QEKDILWKLREYCIQVPQSLPKLLQSVKWNEREYVAQLYMLLRRWPRLMPEFAMELLDCS
YPDLCVRQYAVTCLDHGFSDDKLQQYMLQLVQALKFEPYLDSPITRFLLKRALQNQKTGQ
LFFWHLKSEIHNTSIQLRFGLVLEAFCRGCGSNLKMLLRQVEALDKLTKLTNMIKNEVKD
DINEIMKFLANQLQQPDYQDGLKNFLSPLDNSHILGDLDISHCSVMTSKKKPLWLVFSNP
DVMADIWFTDYKLIFKNGDDLRQDMLTVQLFKIMDTLWKNEGLDLRLIPYSVISTGKDVG
VIEIVRDSSTIMSIQQKNGIRAAVQMDSLGLYNWIMYHNKDREEQAISNFTRSCAGYCVA
TFILGIKDRHSGNIMVRKNGQVFHIDFGHFLDHRKKKFGITRERVPFVLTMDFIRVIARG
SDQPLKHKEFKKFQQLCCEAYLIIRKNAYLFINLMTMMLSCGIPELQSLDDISYLRKTLA
VEEKDDEKALKYFIAKFNSAYSDAWTVKTDWLFHYMKNR
>A0A091JR64|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Egretta garzetta|TrEMBL
SRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGL
GTGFLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPK
MAAKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQGLSGLSKSSGLRLSPLYDLSCDSHEQKLQLKEILERRSHTELYEHEKD
LVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPD
RYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFW
HLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKP
QTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETG
GGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMH
SDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGLSCAGYCVATYVLGIGDRHSDNIMI
RETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCE
KAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNE
ALRESWKTKVNWLAHNVSKDNR
>A0A7J8FAM9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Molossus molossus|TrEMBL
MPPGVDCPMEFWANEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPSRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRKPLVEQPEDYA
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPCSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVCSNPNTESAAALVICLPEVAS
CPVYYPALDKILELGRHGEHGRATEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQLPQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAI
KSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPQTKELMHL
CMRQETYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSGGSVGII
FKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANI
QLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFR
GYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRV
KFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A671T3A9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPAKTDQLDLWAESGLDGDVQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGDAYEHSSHCTCDYVLDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRS
DYVLRVSGRFEFLFEDHPLNQCKVRYVARNSLEMSNYIFQGSLLLIWQKYSTLHTVFKAM
GSLVSSFIQVRAGLFHGTELLCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFA
IYAVMDKVKKQRSTKNTHLNKYQTILCSGNAFFFLCVADELEEMLNPIGTIQTNPYTENA
TELHISFPEYSTQPVVFPAFDKGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRYDC
RENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVI
CLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMYMP
AVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVSELIKLGTIKTKTKQAHLKEAMM
TCLRQTGFIETLSDLQSPLNPNILLAGVHVERCKYMDSKMKPLWIVYNNKLLGGDTVGII
FKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADTIANI
QKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGNFR
QYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQ
KFDEALRESWTTKVNWMAHIVAHPS
>A0A671RDC3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSPELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTEADIEQLRQLSNRDPL
SEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMSLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A8C0B8P6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Buteo japonicus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPAKNIFVNVRFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGQTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAL
HPVYYPSFEQLLELGRNGEQPRQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQ
ALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLT
DHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRF
GLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCMKQETY
LEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLR
QDMLTLQMIQLMDILWKQEGLDLSDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCE
KAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A1V4K1I8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Patagioenas fasciata monilis|TrEMBL
MAWQPGTGTCGRPLLYKQISSGMELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELI
SIEFILPTSNKHTKVPEMMLLEIAGNCTVEQMKAQIWMRAIEMSQTADFYHAFTPDQFIL
QYQKKGQWYEIYDKHQVLQTLDCILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLI
GYDVTDVSNVHDDELEFTRRRLVTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNN
NIFIIIHRGTTSQKIKVSIDDTPDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRD
EYITGETPIKDFHWIRQCLKNGEEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQ
LTIDGKDHERVFTISLWDCNRKFRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRR
TSSKPFTEEVLWNIWLEFDIKIKDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSK
CKTQLLYYVNLLLIDHRFLLRSGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMA
ISIVLDKYCHPIALPKHRITSDPQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELL
WHFRYESIKHPKAYPKLLSSVKWGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNF
SDENVRAMAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFL
FWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLHDFMKQVQVIEWLHKVTMEIKSVSAE
KYDVTSQVIAQLRQKLEKLQSSKLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEF
KCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNK
IGMIEIVKDATTIAKIQQSTVGNTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGY
CVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVM
GTSGKKTSLHFHKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDAL
TVGKSEDDAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3B5LG20|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xiphophorus couchianus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHDLFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGSHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMSKESLYSQLPME
NFTMPSYARRISTATPYMNGETATKCLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYVTEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMSMIEDHANWNISRELGFNYSHPGLSNRLARDKPLTESDNEQLRQVCNRDPL
SEITEQEKDFLWSHRHYCINIPDILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVTRQPAAASLSSTLEECRMMSSAKRPLWLNWENPDMMSELLFQNNEIIFKN
GDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCK
GGLKGALQFNSHALHQWLKDKNKGEMYDQAIDLFTRSCAGYCVATFILGIGDRHNSNIMV
KDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEM
CYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQEALDYFMKQM
NDAHHGGWTTKMDWIFHTIRQHAMN
>A0A3L7IA30|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cricetulus griseus|TrEMBL
MPPGVDCPMEFWTKEESQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVDDFRTKMRQFCEEVAAHRQQLGWEDWLQYSFPLQLEPSARSWRA
GILRVTNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGRHEYLYGNYPLCQFQYICSCLHSGLTPHLTMVHASSILAMRDEQSNPAPPVQKPR
TKPPPIPAKKPSSVSLWSLEQPFCIELMEGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWRQRLEFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSRKADCPIAW
ANLMLFDYKDQLKTGERRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEILE
LGRHGEQRGRITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQEHFPEALARLLLV
TKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRKLTDDELFQYL
LQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYC
RGSTHHMKVLMKQKTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTF
MDSKMKPLWIMYSSEEAGSAGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMT
PYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRA
IEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVP
FILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGKTEEEA
LKQFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A672UWK0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GPLHIPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAIKKQATVFRHETLEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKTA
TKPPPLPKKKPNYGSLWSLEQSFYIQLVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRMISLLQTWPELPVLNALELLDFSFPDRYVGSFAVNSLK
KLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVA
LRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMMHVCMKQ
ETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGD
DLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKS
NMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIR
ETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEK
AYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYWH
>A0A2K5RDK8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cebus imitator|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSAAASLSPMELIPIEFVLPTSQRSCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKAMHRSPGQIHLVQRRAPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKYLMDIPESQSERDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKAPAESPSSESKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCYPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIETLQKVTLDIKSLSAEKYDVSSQVIAQLKQKLENLQNSHLP
KSFRVPYDPGLKAGALAVGIIWMSPCGLLFVPYMDIPQFVFHSFLSKCLTVG
>F7INV3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callithrix jacchus|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSAAASLSPMELIPIEFVLPTSQRNCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRAPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKYLMDIPESQSERDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKVPAESPSSESKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCYPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVIAQLKQKLENLQNSHLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSKETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8C7MHV9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPRPSSGELWGMHLMPPSIMVDCLLPNGMILTLECTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDAEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKAQPRTAYICINLQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLKMCVQE
YQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPIDTFTMP
SYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGE
QLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWG
NINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHFSNPVK
FPDMPAIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPLSEITE
QEKDFLWRHRHYCVSIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCN
FPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGH
FFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLKQEKKD
EAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWEN
PDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCV
GLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRSCAGYC
VATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVIS
KGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKT
LALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A6J3DGX4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aythya fuligula|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A850XHM5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Piaya cayana|TrEMBL
MPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQNEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYSFPLQLEPMAKGFGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLLQGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMS
AKPPPLPKKRPNYGSLWSLEQPFYVELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTDSAAALVICFPSVAS
HPVYYPSFEQLLEVGRNGEQPRAALEDPEEKLQLKEILERRSYTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELLQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKSLNDFVKSSSQKTTKPQTKEMMHV
CMKQETYREALSRLQSPLNPNVILAEVCVDQCTFMDSKMKPLWIVFNNEETGRGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFESRFR
GYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRL
KFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K9Q680|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Irena cyanogastra|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGN
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKEKCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C4G6U0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MEQQCSDDESPLVPSRRRRRKMKAFTSSSAVGSEQLTVEFVLPTTSKTSNAPDTLNLEVA
GNCTVEQVKAQVWLKAVADQISPQFYEKYSPDHCILCYQKKGSWCEIYDRHQVFQTLDCI
RYWKVLKKDVGKIHMYRRPQPSEESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLT
PRKIELSDRDARLYSMDPWVTTKPLPEYLTSRISNGHVLLVIHRNTSSQTIKVSIDDTPF
QVLQSFFTKIANKKALLDIPENVTESDYVLRVCGREDYVFGNYAIKDFHWVRQCLKNGEE
IHLVLESAPNPDQDVVEKEDWSQVDDCTGVAGTHEQLTIDEKDHDKVFTISMWDCNRKFR
VKVLGIDIPSLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNAWLEFNIKIRD
LPKGSRLSLQVSCGKAQTQTSKVSNLDGSFDGRCKSRLLYYVNLLLVDHRSLLRQGEFVL
HMWKMPDKSEDNSSVNADKLTSATNPDKTSSMAVVIMLDKYCYPVALPKSPESRDSEAEG
DRGQREMPNHLRKQFQQIVSTDPLHPLSPEDKELLWHFKQECLRNPKAYPKFLGSVKWGK
QEAVMTTHQLLERSTTWDRSQLDVGLAMQLLDCHFSDTNVRSMAVRKLETLDDDDVLRYL
LQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAY
LRGCGNAMLQDFKKQVEITEALQNVTREIKAISVEKYDVSAQVVLQLRQKLESLQSSGLP
ESFRVPYDPGLRAGGLVIEQCKVMASKKKPLWLQFKPADPTTLSSDTIGIIFKDGDDLRQ
DMLILQILLIMESIWEAESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSIVGNTG
AFKDEILSQWLRDKCVSEDKFQQTVERFVYSCSGYCVATYVLGIGDRHNDNIMVTEAGNL
FHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFLKFQEVCVKAYLAL
RQHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEDDAQRHFLDQIEICRDKGW
TVQFNWFLHLVLGIKQGVEKRSA
>A0A8C4FWR9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPTMMDVLDLWAELGEVEHVSVDFLLPTGLYIQMEVPREATIQHIKQLLWKEAAGYPLF
TLLGAMEGHMFECVNQTAVHEELEDETRRLCDVRPFLPVLRVVTRSGGHNERLLDSKIGV
LIGKGLHELDSLQDQEIKDFRTKMQQISKEKIQRIQVMSWEEWLRTHFSPQLEVGQVDGM
IEKLCEDGIKVTMHYDQSQDTVSVRVDVSCTVRTLLELALRKWANTHGHNNSSCLSDYIL
RISSKLEILFEEHPLIQYKYIRECLLAQESPHLTVMHSSVLRGMFERELGCIASVCGHKQ
SNAPLPLPPKKRPPSQMHTCVWDVQSQFKITLVRGIKVNTEESAKVYVRAGLFHGAELLG
KPAVSSDSSGRLEHLWNTTLEFDVAVSDLPRMSRLCFAIYAVMDKVKKQPKSIKTPHSKY
QTIRKAGKVHYPIAWVNTMVFDYKGLLKTGDVVLYCWSSFPDELEEMLNPIGTVQTNPYT
ENATAIHITFPEYSQISVIFPPFDKILEKAAEMARGSDCPPMGRGGKKFHIELKEIMDRE
PLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWNKHEDMAQLQALLQIWPTLSHRD
ALELLDFNYPDQYVREYAVNCLRDMSDEELSQYLLQLVQVLRYEPYYDCALSRFLLERSQ
LNRNIGHFLFWHLRSEMHMPAVSVQFALILEAYCRSSIPHIEVLKKQVEALNKLKAVNAL
VKTGAVKSKARTKDSHLKEAMLTCLRQSGFTETLSDIHSPLNPSVLLAEVNVDRCKYMDS
KMKPLWIVYNNKLLGGETLGIIFKNGDDLRQDMLTLQILKLMDLLWKEANLDLRIVPYGC
LATGDHSGLIEVVSSADTIANILKTSSNMAATAAFNKDALLNWLKEKNSGDTLERAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
HDFIHVIQQGKTANTEKFGSFRQYCEEAYLVLRRNGNLIITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFRQKFDEALRESWTTKVNWMAHHIAHAS
>A0A093HGP8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Struthio camelus australis|TrEMBL
DSTMPPAMTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQVKPNGQ
LNDGLIYIQKENLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDP
GEKLDSKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPP
EQEPVIQESFQDKLYSGNLVVAIHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKE
DEEVDPADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEM
IAIEAAVNRKSSNLPLPLPPKKTRITTSVWDICNPFKIVLLKGNKLNTEENAKVHVRAGL
FHGTELLCKTVVSTEISGRSDHVWNEILEFEINVCDLPRMARLCFAVYAVMDKVKTKKST
KAMNPSKYQTIRKAGKVHYPVAWVNTMIFDYKGQLKNGELMLHSWSSFPDELEEMLNPMG
TVQTNPYTENATALQIRFQEYSKQPISYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYV
VLKDIMERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQ
IWPKLLPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCAL
SRFLLERALANRRIGQMLFWHLRSEIHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEAL
NKMKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKC
KYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRI
LPYGCLATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDR
AIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERV
PFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRKHGNLFITLFALMLTAGLPELT
SVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A850X4A4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Piaya cayana|TrEMBL
MELQDYEQPVVMREENKRRRRRMKPHCTSSNLSSMEMISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQPPSEVVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGVSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSILDVGLTMQLLDCNFSDENVRAMAVQKLESLDDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSASAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C4AYC8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPTMMDVLDLWAELGEVEHVSVDFLLPTGLYIQMEVPREATIQHIKQLLWKEAAGYPLF
TLLGAMEGHMFECVNQTAVHEELEDETRRLCDVRPFLPVLRVVTRSGGHNERLLDSKIGV
LIGKGLHELDSLQDQEIKDFRTKMQQISKEKIQRIQVMSWEEWLRTHFSPQLEVGQVDGM
IEKLCEDGIKVTMHYDQSQVCTVRTLLELALRKWANTHGHNNSSCLSDYILRISSKLEIL
FEEHPLIQYKVYIFFFSIPLLCLSLSSQQQMHTCVWDVQSQFKITLVRGIKVNTEESAKV
YVRAGLFHGAELLGKPAVSSDSSGRLEHLWNTTLEFDVAVSDLPRMSRLCFAIYAVMDKV
KKQPKSIKTPHSKYQTIRKHYPIAWVNTMVFDYKGLLKTGDVVLYCWSSFPDELEEMLNP
IGTVQTNPYTENATAIHITFPEYSQISVIFPPFDKVLSFFFYLYLCTLGMFVFLLDSGES
CRDGQRKRLSPHGSECLHHSYNKDSLKEIMDREPLSQLCENEKDLIWTLRYDCRENFPQS
LPKLLLSVKWNKHEDMAQLQALLQIWPTLSHRDALELLDFNYPDQYVREYAVNCLRDMSD
EELSQYLLQLVQVLRYEPYYDCALSRFLLERSQLNRNIGHFLFWHLRSEMHMPAVSVQFA
LILEAYCRSSIPHIEVLKKQVEALNKLKAVNALVKTGAVKSKARTKDSHLKEAMLTCLRQ
SGFTETLSDIHSPLNPSVLLAEVNVDRCKYMDSKMKPLWIVYNNKLLGGETLGIIFKNGD
DLRQDMLTLQILKLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADTIANILKTSS
NMAATAAFNKDALLNWLKEKNSGDTLERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVR
STGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTANTEKFGSFRQYCEE
AYLVLRRNGNLIITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFRQKFDEA
LRESWTTKVNWMAHHIAHAS
>W5P3X5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ovis aries|TrEMBL
MGNCSKGGPSFGGDEEPYQVTQGMELENHEQPVVLREDNCRRRRRMKPRSTAASLSSMEL
IPIEFVLPTSQRNTKTPETALLHVAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFL
LLYQKKGQWYEIYDKYQVVQTLDCLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTAL
IGYDVTDVSNVHDDELEFTRRRLVTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITN
NCIFIIIHRSTTSQTIKVSADDTPGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGR
DEYLVGETPIKNFQWVRQCLKNGEEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHE
QLTIHGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQR
RTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGK
AQLLYYVNLLLIDHRFLLRHGEYVLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSIS
ILLDNYCHPIALPKHQPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWH
FRYESLKDPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSD
ENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFW
FLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKY
DVSSQVIFQLKQKLEILQNLNLPQSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKC
ADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIG
MIEIVKDATTIAKIQQSTVGNTGAFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCV
ATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGT
SGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTV
GKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A091RSG5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nestor notabilis|TrEMBL
MELEDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAANCTVEQMKAQIWMHALEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQNPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMRPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIRDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSAKTNLQSHESPNSDPKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQGI
>A0A7L2GRP2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nyctibius grandis|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKALGT
GPLQTTTKNIFVNVKFQSGGESFTFQISPKEFPVTLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGQTPHLTMVHSSTIIAMRDEQTNCIASPPKMI
AKPPPLPKKKPNYGSLWSLEHPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLPMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHDDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8B9F0S4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amazona collaria|TrEMBL
MPVGSAAGRGDFVWCPWPSLTTGCCGCGRARALQWIFSGMELEDYEQPVVMREENKRRRR
RMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLEIAANCTVEQMKAQIWMRALEM
SQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLDCILYWKVLQKKVGKIYVVQKQ
NPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRLVTPRMIEVACRDPKLYAMHPW
TTSKPLPEYLLKKITNNNIFIIIHRGTTSQKVKVSIDDTPDMILHSFFTKMAKKKSLMDI
PEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNGEEIHLVLDNPPDPSEDEVQKE
EWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRKFRVKIIGIDIPVLPRNTDLTV
FVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKIKDLPKGALLNLQIYCGKAQGL
STKTNLQSHESPNSDPKCKTQLLYYVNLLLIDHRFLLRSGEYVLHMWKIPGKGEEQGSIN
ADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSDPQGDRIRAEMPNQLRKQLEEI
IATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQEIVAKTYQLLAKKEIWD
QSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALA
RFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLQDFMKQVQV
IELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSSKLPESFRVPYDPGLRAGALVI
EKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWEAE
SLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEILNQWLKERCMIE
EKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGI
NKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAYLALRHHTNLLIILFSMMLMTG
MPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGV
EKHSA
>A0A6A5E4K5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Perca fluviatilis|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMLLTLECLREATLITVKHELFKEARKYPLYN
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESCAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPCAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMTIIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDVDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQHCVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8C3TRR0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hylocichla ustulatus|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKSMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLRSGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPVNYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C3TRR0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Catharus ustulatus|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKSMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLRSGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPVNYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C3UGK2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Catharus ustulatus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVRDPEVSDFRAKMCQFCEEKAAKRQQLGWAAWMEYNFPLQLEPVAKGLGT
GSQQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIRKQATVFRHETVQRPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCVQRGLTPHLTMVHSSAILAMRDEQNSCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVSDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8D3DUX2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNLESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYRYSTAARGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRTGIYHGG
EPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARICLSICSVKGRKGAKEEHCPLAW
GNVNLFDYKDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFSWFNQTV
VFPDEQQIEEHANWTISRELGYNYCPGLTSRLACDVSVSAADAEQLRCLCSKDPLYELSE
QEKDFLWRHRHYCVNIPESLPKLLMSVKWNSRDEASQMYCLLKEWPLMEPESALELLDCN
FPDPMVREFALRCLVKGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGH
FFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQEKKD
ETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWEN
PDIMSELGVVGNVVCTVCVSDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCV
GLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTRSCAGYC
VATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVIS
KGVQESTKTKEFERSRLHCALGQYIIKGFVCEVQGFESFSEFYRDVSTGEI
>H2PN59|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pongo abelii|TrEMBL
MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGFLLLYQKKGQWYEIYDKYQVVQTLDCLR
YWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGLVTP
RMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDTPGT
ILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGEAPIKNFQWVRHCLKNGEEI
HVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRKFRV
KIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDL
PKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEYVLH
MWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEGDRV
RAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEI
VAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQL
VQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRG
CGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPKSF
RVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDML
ILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFK
DEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQ
FNWFLHLVLGIKQGEKHSA
>A0A673HUE6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MVWTRCCLGVWQKESGTVGGARGGTEGGDCLLWKEAQTYPLFSLLGEMEGHMFECVNQAA
VHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKIGVLIGKGLHELDALQDQQVK
DFRSKMKRVSEEKMQRMQLMSCGEWLRSCYSTQLGTGSLENLIDKHEGVIKITMHYDQSQ
VCSVILILSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDYVLRVSGRFEFLFEDHPLNQ
CKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLARKTSNPPLPLPPKKRPPTVS
TLSVFPAHQLIKGVLSFVHLAAPNSNAKIQVRAGLFHGTELLCKTAVSSESSSRSEHVWN
KTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIPWVNTMVFDYRGQL
KTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVFPAFDKVC
IYSQYEHDSQMYTYTHKCTHVKLKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPK
LLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVICLRDMSDDEL
LQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMYMPAVSVHFALIL
EAYCRGCIPHIEVLKKQVEALNKLKAVSELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIE
TLSDLQSPLNPNILLAGRCKYMDSKMKPLWIVYNNKLLGGDTVGIIFKNGDDLRQDMLTL
QILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQKTSSNMAAAAAFN
KDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHID
FGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNG
NLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKV
NWMAHIVAHPS
>A0A4W2GB16|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos indicus x Bos taurus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAILELGR
LGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQEHFPEALARLLLVTKWN
KHEDVAQMLYLLSSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLV
QVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGST
HHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLD
PSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKNGDDLRQDMLTLQMIQL
MDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALL
NWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFL
GNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLH
LFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAH
NVSKDNRQ
>A0A673IBW2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYSMPLEAGSLE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGFRSDY
VLHVSGKLEFLFEDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIGSVLAR
KTSNPPLPLPPKKRLPTQLHTCVWKVHSLFRINLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKPRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWTSFPDELEEMLNPIGTIQTNP
YTENATELHINFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSP
RDALELLDFNYPDQYVREFAVYCLQDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLER
SQSSRKIGHFLFWHLRSEMFMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVN
ELIKFGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGINVERCKYMDS
KMKPLWIVYNNKLLEGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGC
LATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
HDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A673HQD1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRVSEEKMQRMQLMSCGEWLRSCYSTQLGTGSLE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDY
VLRVSGRFEFLFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLAR
KTSNPPLPLPPKKRPPTQLHTCVWKVHSLFRINLVKGNKVNAEDTAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWTFQNSLCCAPSRSVSVHFALI
LEAYCRGCIPHIEVLKKQVEALNKLKAVSELIKLGTIKTKTKQAHLKEAMMTCLRQTGFI
ETLSDLQSPLNPNILLAGVHVERCKYMDSKMKPLWIVYNNKLLGGDTVGIIFKNGDDLRQ
DMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQKTSSNMAA
AAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQ
LFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGNFRQYCEEAYLI
LRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRES
WTTKVNWMAHIVAHPS
>A0A2J8KXT1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan troglodytes|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSSGATVKGPTP
SCGATGFSSSTSLP
>A0A0A0A465|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Charadrius vociferus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A4W6CSU3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLQH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYCKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCITVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLSDLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYQDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKDWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFMRTPGGQVEYDRRTTNRLRQK
>A0A7K7DLF8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pheucticus melanocephalus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPTKNIFVNIRFQSGGESFMFQISPWEFPITLMSYAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7K5G5A2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chunga burmeisteri|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCMSSSLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTAEFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSAKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVVAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A1A8BWE9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius kadleci|TrEMBL
MPPGKYGMQEEWEKGGDQNILMDFLLPTGIFLKFPVPRNDTIKNIKKMVWRNAKTEALYC
GLGDPEGYVFTCINDTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNSHISSL
IGKGLHEFEAQKNHEVDEFRSKMRTFCEEKALERHNLPWQQWMEYSFPCDLEPCCSPPVH
GGTKSKHTKKLFINVKFEACDESFMLQQDPLDIPVALMKSALKKRATVFRSVRQEPEDYT
LQVSGRWEFIYGNHPLRQFKYIFSCLRNGQNPQLIMVHHSTISKYQEEQGQLCSQVGKIR
SQSRPPPLPMKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQKLDFDINVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKRADCPI
AWVNTMVFDYKDQLKTGEFILSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPPLDKMIVMERNGDAVFATKVERMRLKEIMDNKNSTEFFEDEKELLWKLRTEV
RDCYPESLSKLLLITKWSKREDVVQMVSLLRNWPDLPAIQALELLDYSFPDPAVRSFTIR
CLRKLSDNELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVA
SVSLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDIVKSGCQKMTVEDLKLCIRQE
SYMEALSNLMSPLNPSIILVELCADKCRFMDSKMKPLWMMYKNPSEHADMVGIIFKNGDD
LRQDMLTLQMIHLMEDLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKHSDTIANIQRNNSN
SAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEWA
YKILCKNGTLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEDEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A484DJK8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Perca flavescens|TrEMBL
MPPAMTDLLDIWAAHSPLAGHALDQITVDFLLPTGIYIQMEVPREATIQHIKLLLWKQAQ
SFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRSCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRLSEERMQQVQMMTCTEWLQACFSPQLEPL
AGTAITDGLNDRPADLKVIIHFDQSQDSASLKVPSSCIPSDLMEMAVKKWLTTHGPEEEA
WLGQYILRVSHCLEFLCGEQPLIQYKYIRTCMQAKESPHLTLVHTSTVKGMFDKEISAIR
AVVSRKSSNPPLPLPPKRRVPTQLQKCVWDVSSPFKIVLVNGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESSGRSDHTWKDSTLEFDLSVSDLPRMTRLCFAIYAVMDKVKKQKST
KNVHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHSIVFPPFDKILEKAAEIAGASDSVPMGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALMLEAYCRGSIPHIEVLKKQVEALS
KLKSVNELIKLGTIKNARNKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGI
NVERCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAN
LDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNTG
DALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLALRKNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDEDALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C3DS23|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Corvus moneduloides|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSVSVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTTVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRVSLHLFQHQRLW
>A0A4D9DZW3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Platysternon megacephalum|TrEMBL
MPPAMTDVLDIWAVDSQIGADGLISVDFLLPTGTYINLDVPRDATICHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVKEFRSKMRRISEEKLLSLVGLSWVDWLKHSYPPEQEPSIPE
NFQDKLYGGNLVVAIHFDKCQDVFSFQVSPNINPVKLNELAIRKRLTIHGKEDEVDPSDY
VLQISGRLEYIFGDHPLIQFQYICKCVMNRTLPHLTLVECCSIKKMCEQEMIAIEAAINR
KSSNLPLPLPPKKTRTVTQLTQSVWDISNPFKIMLLKGNKLNTEETAKVHVRAGLFHGTE
LLCKPIVSAEISGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKTINP
SKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDLLLHSWTSFPDELEEMLNPMGTVRTN
PYTENATALHIKFQEYSKLPIYYPPFDKILEKAAEIAKSSENAGMAGRGGKKFYIELKEI
MERDPLTQLCENEMDLIWTLRYDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWSKL
PPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFFDCALSRFLV
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGVILEAYCRGSIAHMKVLSKQVEALNKLKT
LNSIIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELYVEKCKYMDS
KMKPLWIVYNNKMFGGDLLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGC
LATGDHSGLIEAVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGR
>A0A669EI13|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRCKMFRISEERMQQIQMMTFSEWVQACYSPQLEPA
AVTAITAGVNDAPFPFLQDSASLKVSLSCTPNELMEQALKKWLTTHGSEDAVWRGQYILR
VSQCLEFLGGDHPLIQYKYIRSCLQAKDTPHLTLVHTSAVKTMFDKEISAIGAVVSRKSS
NPPLPLPPKRRAPTVSPNIMHDSVNNIISIFMILVKGSKVNAEETVQVRAGLFHGTELLC
KPAVSNESSGRSEHTWKDNTLEFEISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNPHINK
YQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPY
TENATALHIHFPEYSSHPIVFPPFDKVTQHSIVIFSFFDSMSLGRGVKKFYMELKEIMER
DPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPR
DALELLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERA
QRNRQIGHFLFWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQVEALSKLKSVNE
LIKLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDINVEKCRY
MDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVP
YGCLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAI
EEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPF
ILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSV
KDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A093GHE1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dryobates pubescens|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSTEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTISSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANPYIRKTLALDKTEQEALEYFMKQM
NDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C8JFP7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPRPSSGELWGMHLMPPSIQVDCLLPNGMILTLVCTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANCNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCGTIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERYSFTILCYVSFPISEY
>A0A8C8JZJ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MVWRNASSEPLYGALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGD
RVEKLTNTQISLLIGKGLHEFDSQKNHEVNEFRVKMRSFCEEKAQDRQRLPWYQWMEYSF
SCDLEPCVSLAEPGGIKTKGTKKIFVNVKFEASDVSAFNDIFDWKIQNFYQCIDQVKIWR
MTLGIKKYKKLRQEKPEDYTLQVNGRWEFIYGKYPLCQFKVSKHNNTTHVLFLSYYQQNT
SSLWSIEEPFHIHLLQGYRVNADEGMKVGVAGLFHGSELLCKVVTSGEVNVCSEPLWDQK
LVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPLAWVNTMVFDYKDQLKT
GEFLLSTWPSVPGDLLNPMGTVEKNPNVDSAAGLLIHFPNIRPHPLYYPHFDKVIATKVE
VRDSLLFFFEDEKELLWKLRGVVRERYPESLSKLLLITKWNKHEDVAQMVTFLQKWPDLP
ALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLE
RALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGNIYHIKSLWKQNEALNKMKAL
NDFVKSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLLSPLNPSIMLSEICADRCKFMDSK
MKPLWLMYKNKWVQGDTVGIIFKNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCL
STGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFT
LSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTY
DFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQ
YLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDSRL
>M3XAA6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Felis catus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLLERPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSAPDEKGELLNPAGTVRSNPNTESAAALVICLPEVSP
YPVYYPALDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPDLPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMRQGEALSKLKALNDFVKVSSQKTTRPQTKELMHLCMR
QETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDSSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGPLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>F1QVE6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Danio rerio|TrEMBL
MEQQASDDEPPVVRREENKRRRRRMKAFTSASAVSMEHIAVEFVLPTTNKNSKTLDTLQL
DVTGNWTVEQVKVQLWHRAVTSKLCPEFYQKYSPDYCILLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKDVGKIHLVVRQQPAEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDPNLYSMDPWMTTTPMPEYLLSKISNNHILMVIHKETTSQTIKVSIDD
TPVQVLQSFFAKITNKRALLGISEDVSESDFVLRVCGREEYLYGNNAIKDFHWIRQCLKN
GEEIHLVLEHPPNPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTSSKPFTEEVIWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKETECKNKSRLLYYVNLLLVDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKNNSMAVAILLDKYCYPVALPKSKDSPDIEGERGQR
EMPNHLRKQFEQIIATDPLHPLTSEDKELLWHFRQECMRDPKAYPKFLSSVKWGKQEAVA
ITHYLLERSTIWDRSVLDVGLVLQLLDCHFSDENVRTIAVRKLETLGDDDVLRYLLQLVQ
AVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCG
EEMLQDFRKQVEITEALQKVAREIKQISAEKYDISAQVVFQLRQKLEGLQVLGLPDSFKV
PYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDMLIL
QILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDE
ILSQWLREKCVNEDKHQQAVDRFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDF
GHILGNYKSFLGISKERVPFVLTPDFLYLMGTTGKKSSPNFLQFQNVCLKAYLALRHHTN
LLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQFN
WFLHLVLGIKQGVEKRSA
>A0A7K8BLL5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhagologus leucostigma|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTTNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPNPDEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPVALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVVAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A851F9F2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pitta sordida|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGP
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYSSLWSLEQPFHIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSIHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEESGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A5F8GSW7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodelphis domestica|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGQI
IVVIWVIVSPNNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKY
ILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLDTFTMPSYSRR
ISTATPYMNGEASTKSLWVVNSALRIRILCATYVNVNIRDIDKIYVRTGICHGGEPLCDN
VNTQRVPCSNPRWNEWLMYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLF
DYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSNPVKFPDMA
VIEEHANWTVSRELGFNYSHAGLSNRIARDNELRENDKEQLRAICTRDPLSEITEQEKDF
LWSHRHYCVSIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPM
VRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWH
LKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKV
QMKFLVEQMRRPDYMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMS
ELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEV
VRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFI
LGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQE
CTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDK
TEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A2Y9F6Y3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Physeter macrocephalus|TrEMBL
MELENHEQHVVLREDSRRRRRRMKPRSAAASASSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLSPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRLAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDTKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PDTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIRNFQWVRQCLKNG
EEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKAEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSAKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>G1KDE7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anolis carolinensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVCPPNIESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGESSAKSLWAINSNLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLQYEMQVLDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMSVIEDHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLHAICTRDPL
SEITEQEKDFLWSHRHYCVNMPEILPKLLLSVKWNSRDEVAQMYCLIKDWPPIKPELAME
LLDCNYPDPMVRSFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMKRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDPAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A6Q2YMG7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPTD
CFSMPSYARRISTATAYMNGETSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLAYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSAVKFPDMATVEEHANRTISRELGFNYSQSGQSKRVARDHALTDIDNEQLRQVSAVNCL
APLKPTLAYLHTLANIHCLLLFRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPA
IKPEQAMELLDCNYPDPMIRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRF
LLKRALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKL
INLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNIRLEECRIM
SSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLR
MLLYGCMSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDM
AVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERV
PFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPE
LQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A3P9A3E6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPVEYGMLGEWEKEGDLEIMMDFLLPTGIFLKFSVSHNDTIGAIKKMVWSNASNEPLYG
ALSDMDAYVFTCINSTAEREELEDETRRLCDVRPFMPVLRLVAREGDRVEKLTNTQISLL
IGKGRNYYYYSLHKLMKIVNEFRAKMRSFCEERALERQQLPWYQWMEYSFPCELEPCVLL
AEPGGIKTKCKKIFVNVKFEASDESFMLQHEPQDLPVTLMRSALKKKATVFRSVHQEKPE
DYTLQVNGRWEFIYGKYPLCQFKYIFSCMRGGQTPHLTMVHHTTIVKYQEEQGRLASQVS
RCRSLSKPPPLPLKKLMVQAGLFHGSEMLCKVVTSGEVNVCSEPLWDQKLVFDINVSDLP
RMSRLCFALYAVIEKNKKPRSTKKKNKKADCPLAWVNTMVFDYKDQLKTGEFLLSTWPSV
PDDKGDLLNPMGTVEKNPNIDSAPGLLIRFPNIRPYPLYYPPLEKVRLSFPAHSQTLFSN
WYLDNKNYTEFFEDDKELLWNLRGVVRQRYPESLSKLLLITKWNKREDVAQMVDLLHKWP
ELPALHALELLDYCFPDPRVRSFTIRCLRKLSDEELLQYLLQLVQVLKYESYLDCDLTTF
LLERALANKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGNICHIKSLWKQNEALNKM
KAVNDFVKSGWQKTSRQQMTDDMKLCIKQEAYIWALSNLLSPLNPSIILSEICADRCKFM
DSKMKPLWLMYKNKCVQGEAAGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPY
GCLSTGNKTGLIEVVKNSETIANIQRNNSNSAATAAFNKDALLNWLKSKNPEDKLDNAIE
EFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFI
LTYDFVHVIQQGRTNNSEKFERFRAYCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFK
DIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDSRL
>A0A851B3V2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Picathartes gymnocephalus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGT
GSLQIPIKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKVA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLDFDINICDLPRMARLCLVLYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3B3TQ81|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia latipinna|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEENSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDNNGSHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDSVPEQVIAEAIRKKTRSMLLTQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMSKESLYSQLPME
NFTMPSYARRISTATPYMNGETATKCLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYVTEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMSMIEDHANWNISRELGFNYSHPGLSNRLARDKPLTESDNEQLRQVCNRDPL
SEITEQEKDFLWSHRHYCINIPDILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHALHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A3Q3RAC7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monopterus albus|TrEMBL
MPPAMTDLLDIWVTHSPLAGQASDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
KFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRGKMCRVSEERMQRVQMMTCTEWLQSCFSPQLEPA
GGTAITDGVSDRPADLKVIIHFDQSQVRVCNSLLEMMKTLMELAVRKWLTTHGPEEETWR
GQYVLRVSHCLEFLLGDHPLIWYKYIRTCIQAKESPHLTLVHTSTVKAMFEQEISTISAV
VSRKSSNPPLPLPPKRRPPTVIQTCVWDMSSLFKIVLVNCSKVNAEETAKVQVRAGLFHG
TELLCKPAVSGESSGRSDHTWKESTLEFEIAVCDLPRMTRLCFAIYAVMDKVKKQKSTKN
AHINKYQTIRKAGKVHYPIAWINTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTI
QTNPYTENATALHIHFPDYSYHPIVFPPFDKVRDPSVIGRGGKKFHIELKEIMERDPLSQ
LCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPRLSPRDALEL
LDFNYPDQYVREYAVDCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQRNRK
IGHFLFWHLRSEIHMPAVSVQFALILEAYCRCNIPHIEVLKKQVEALNKLKSVNELIKLG
TIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPLVLLSGINVERCRYMDSKM
KPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDSLWKEANLDLRIVPYGCLA
TGDRTGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFTL
SCAGYCVATYVLGIADRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHD
FIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7K7KBH9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Agelaius phoeniceus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPNKNIFVNIRFQSGGESFMFQISPWEFPITLMSYAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPNCGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFDIR
DQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREAFSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7L3C034|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pelecanoides urinatrix|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPTTLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIQSCLHRGRTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKREDVAQMISLLQTWPELPVLNALELLDFSFPDCYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A1A8G1L1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius korthausae|TrEMBL
MDRQQIQVSDEEREVPREETRRRRRKKAITSSSSISMDQITVEFVLPSAARDRSSSDSLQ
LEVAGNWTVEQVKAQLWMKAVTLNFCPDFFQRLSPDHCILLYQKKGTICEIYDKHQVFQT
LDCIRYWRALKKEVGRIQLVPRPQPTDESLQYQRYLNHLIGYDVTDVSNVHDDELEFTRR
KLLTPRRVELSDRDPKLYSMDPWVTHKQLPEHLLTKVNNSYILVVIHVSTSSQTIKVSID
DTPSQVLASFFAKTQNKRVLLGIPDNMCESDFVLRVCGREEYLYGEKPLQDFNWIRQCLK
GGEEIHLVLEAPPDPELDLVQKEDWAQVDDCTGVTGTHEQLTITEK
>A0A834C2L7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias melastigma|TrEMBL
MDRRSIQVSDEEPEAPHCRRRRRKKAITPSSCASMDQITIEFVMPSVARGGNSPDVLLLD
VAGNWTVEQVKAQVWMKAVTLNLCPDFYQRLSPDHCILLYQKKGTVCEIYDKHQVFQTLD
CIPYWRALKKGVGRIQMVPRPQPSEESLQYQRYLNCLIGYDVTDVSNVHDDELEFTRRKL
LTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVNNGHILVVIHIGMVSQTIKVSINDT
PSQVLASFFAKTANKRVLLGIPDDVCEADFVLRVCGREEFLYGEKPLQNFNWIRQCLKNG
EEIHLLLEKPPDPELDVVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRK
FRVKVLGIDIPTLPKVPELVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKI
KDLPKGARLNLQVICGKPTQTPAGKGSSHYDNSGGTGSSEGKTKNRLLFYVNLLLVDHRS
LLRQGEFILHMWKMPEKSDESSSSINADKLTSATNPDKSSSMAIAILLDKYCYPVVLPKS
RDVGRDCGAGEETEGGERGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRQECMR
DPRAYPKLLGSVKWGKQEDVLATHRLLERNNAWDTSGLDVGLAMQLLDCHYSDSHVRSMA
VRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIA
QSMHYQQRYAVLLEAYLRGCGESMLQDFRKQVEMTMALQRVTREVKAMSADKYDVSAQVV
FQLRQKLETLQSSGLPETFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLS
KDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKD
ATTIANIQQRVVGSTGAFKDEILHQWLRDKCVSEDKFQQAVERFLLSCGGYCVATYVLGI
GDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSP
HFLKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEEEA
QRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A8C3F186|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysemys picta bellii|TrEMBL
MELGNYEQPVVMREETKRRRRRMKPYSAASNLSSMELISIEFILPTSNKHTKVQETMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHKFTPDQFILQYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGKIYVVQKQNPAEAVQEFQTQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYSMHPWITSKPLPEYVFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDDPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIVGIDIPVLPRNTELTVFVEANIQHGQQLLSQRRTISKPFTEEVLWNTWVEFDIKI
KDLPKGALLNLQIYCGKAQALSTKVSLQSHDSPNSDSKCKTQLLYYVNILLIDHRSLLRS
GEYVLHMWKISGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEAIVDTDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKREAWDHSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQIIKLLHKVTMDIKSVSAEKYDVTSQVITQLKQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKDRCVIEEKFQAAVERFVYSCSGYCVATFVLGIGDRHNDNIMITES
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTAGKKTSLHFSKFQIGELNPP
SKKDLNRT
>A0A3Q0T472|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amphilophus citrinellus|TrEMBL
MDRRRIQVSDEESQVPREESRRRRRKKAITSSSSNSMDQITVEFVLPTATRGGNSPDTLQ
LDVAGNWTVEQVKAQVWMKAVTSNLCPEFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIGYWRALKKDVGRIQLAVRPQPMQESVEYQCYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKINNGHILVVIHVSKASQTIKVSID
DTPTQVLASFFAKTTNKRALLGIPDNVCEADFVLRVCGRDEYLYGEKPLQNFNWIRQCLK
NGEEIHLLLEMPPDPNLDLVRKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPELIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFSI
KIKDLPKGALCLSGKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEESSSSINA
DKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDWGVGGEEAEGGERGQREMPNH
LKKQFEAIVGTDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRWGKQEDVLATHRL
LERSSAWDTSGLDVGLAMQLLDCHYSDSQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFE
PYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSKHYQQRYAVLLEAYLRGCGENMLQ
DFKKQVDVTEALQKVTREIKTMSADKYDVTPQVVFQLRQKLENLQSSGLPESFRVPYDPG
LRAGPLLIEQCKVMASKKKPLWLQFKRADTTTLSKDPIGIIFKDGDDLRQDMLILQILLI
MESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIANIQQSVVGSTGAFKDEILYQW
LRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILG
NYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQNFQDVCVKAYLALRHHTNLLIIL
FSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQINWFVHL
VLGIKQGVEKRST
>A0A8C2X6A4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MPSGKYGMQEEWEKEGDQEIMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNASSEALFG
ALGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRMFCEEKAQERQMLPWQQWMKYSFPCDLEPCCSPPEY
GSVKSKNNKKIFINVKFEACDESFMLQQDPQDLPVALMRSALKKKATVFRSLRQEPEDYT
LQVNGRWDFIYGKHPMCQFKYIFSCLRNGQNPYLTMVHHSTIHKYQEDQGSMYNQVYKSR
SLSRPPPLPLKKNTSSLWCISEPFYIHLLQGSRVNAGEGMKLVVQAGLFHGSELLCKVVT
TSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVLEKAKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRP
HPLYYPPLDKSFIFSHHGIHALELLDYSFPDPAVRSFTIRCLRKLSDNELLQYLIQLVQV
LKYESYLDCDLTTFLLERALSNWRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHH
IRLLTKQNEALGKMKALSDFVKSGSQKMTADDLKLCIRQESYLEALSDLLSPLNPSIILA
EICADKCRFMDSKMKPLWLMYNPGAQEDMVGIIFKKGDDLRQDMLTLQMIQLMENLWKKE
GLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNP
EDKLDPAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLG
INRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNATLFVNLFAMMKAA
GLPELTSFKDIQYLKVCNN
>A0A8C7WJT5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
TNVSDEEESQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTLLL
EVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQTL
DCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELADRDPKLYSMDPWITSKHLPEYLLFCIGHILLVIHRNKASQTIKVSIDDTP
VQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCLKNGE
EIHLVLESAPNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDCHRKF
RVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFNIRIR
DLPKGARLSLQVSCGKAQTQISKGTSSYQDNGGSPVGGGSGSHDCNKTKSRLLYYVNLLL
VDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYPVA
LPKSREGKEAGGEGREAEGGERGQREMPNHLRKQFEAIVETDPLHPLSQEDKELLWHFRE
ECMRHPRAYPKLLGSVRWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHV
RSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLR
SEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVS
AQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVVKQCKVMASKKRPLWLQFKRADP
TTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIE
IVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATY
VLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGK
KSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRP
EEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A8C7WDI5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MEQVSDEEEPQPVVLREEIRRRRRKMKAFTSTFSVAVDQIAVEFVLPTTTKSSRSPDTLL
LEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQT
LDCVRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRKIELSDRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSID
DTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCLK
NGEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVYTISLWDCH
RKFRVKILGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNAWLEFNI
RIRDLPKGARLSLQVFCGKAQTQISKGGSSSHDGSKTKNRLLYYVNLLLVDHRSLLRQGE
FILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYPVALPKSREGERGQ
REMPNHLRKQFEVIVETDPLHPLSQEDKELLWHFREECMRHPRAYPKLLGSVLWGRQEAV
LATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLETLGDDDVLRYLLQLV
QAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGC
GEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQVVFQLRQKLENLQTSGLPESFR
VPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTTLSSDTIGVIFKDGDDLRQDMLI
LQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSVVGSTGAFKD
EILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLGVGDRHNDNIMITESGNLFHID
FGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFQRFQDVCVRAYLALRHHT
NLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEEAQRHLLDQIEICRDKGWTVQF
NWFLHLVLGIKQGVDKRSA
>A0A8C7W856|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MPPAMTDDLDLWAAHSQLCGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFCPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQACFSPQLEPGGG
ATPVTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISA
IGAVVNRKSSNPPLPLPPKRRGPSQVNTCVWEVSSPFKIVLIKGSKVNAEETAKVQVRAG
LFHGTELLCKPAVSSESSGRSEHVWNRTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKS
TKNAHINKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPI
GTIQTNPYTENSTALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCSSMGRGGKKFHI
ELKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQ
IWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMRYSTHTRTYVFLVHLLDEELSQYLLQ
LVQVLRYEPYYDCALTRFLLNRAQCNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYSRG
SIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETL
SDLHSPLNPSVLLSGINVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDML
TLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAA
FNKDALLNWLKEKNSGDALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFH
IDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRR
NGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTT
KVNWMAHNVVKDNRS
>A0A2U4B9B3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tursiops truncatus|TrEMBL
MPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKQTYPPEHEPSIPE
NLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDEVSPYDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAIEAAINR
NSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKAINPSKYQ
TIRKSGKVDYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALA
NRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLKTLNSLI
KLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYIEKCKYMDSKMKPL
WLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGD
HSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCA
GYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3N0XFU3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabarilius grahami|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGSHSRALYVYPPNVESSPELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTEADIEQLRQLGNRDPL
SEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A8C5PC33|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptobrachium leishanense|TrEMBL
MKVNYKKIKLGTCLLCLVRNPALSTYTFLDRSGQCSSGSTQPFTMPPAVLDPMDIWAVDA
QLHSEISVDVLLPTGIYVQMEVRRDASISHIKQLLWKHAPSYPLYHLLLEMDSYMFECVN
QTAVHEELEDETRRLCDVRPFLPVLKLVSRNCNPAEKLDSKIGVLIGKGLQEFDALNDNE
VKEFRSKMRKISEDKAQSLLRLTWMEWLKCTFPPELEPCVQENIQDKLYSGNLVVAIHFD
NCQDVFSFQVSPNMTPTKVNELAIRKRLTIHGREEEEVDPEDYVLQVSGRQEYVFGDHPL
IQFQYIKSCVMNKSLPRLILVECCNIKKMFDQEISAVELAVKRKTTGPPLPLPPKTRAST
ISQSVWSLLEPYKITLIKGSKLSTEDTTVVVRAGLFHGTELLCKPMSAELSGKSDSLWNA
PVEFEINVCDLPRMARLCLAIYTVDKTQKKKGNKTGNPKYQTIKKAGKMHYPVAWVNTMV
FDYKGQLKAGEHVLHGWSSFPDELEEMLNPMGTVRTNPYIENATALHIKFRDHAKAVYYP
PFDKILEKAAEIARHSDSLTMSGRGGKKFNIELKEIMERDPLCQLCENEKDLIWTLRYDC
RENFPCSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPRDALELLDFNYPDQYVREYAVN
CLKNMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLQRALANRRIGQFLFWHLRSEVHIS
TVSVQFGLLLEAYCRGSVAHMKVLSRQVEALNKLRTLNSLIKLNAMKQSKVKNKESMHAC
LKQNAYKEALTDIQSPLNPSVTLSELVVEKCKYMDSKMKPLWIVYSNRGFGGESMGIIFK
NGDDLRQDMLALQLLRLMDMLWKESGLDLRIVPYGCLATGDRCGLIEVVSAAETIADIQL
DCSNLAAAAAFNKDALLNWIKEFNAGDDLERAIEEFTLSCAGYCVATYVLGIGDRHNDNI
MVRKTGQLFHIDFGHILGNFKSKFKIKRERGPFILTYDFIHVIQQGKPGNTEKFGRFRQY
CEDAYLILRRNGNLIITLFALMLTAGLPELSSVKDIQYVKDSLALGKTEDDALKQFRQKF
DEALKESWTTKVNWMAHTVRKDYNKS
>A0A5N5LTZ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pangasianodon hypophthalmus|TrEMBL
MPPGVYCDLQDVWEKEGLEQVTMEFLLPTGIYLSFPVARNDTIATIKKMLWRNARSEPLF
SILSDPDAYVFTCINRTAEREDLEDEQRRLCDVRPFLPVFRLVAREGDRVEKLINTQISL
LLGKGLHEFDTQKNHEVNEFRTKMRSFCEEKAQERQRLPWHQWMEYNFPCDLEPISVVAQ
SGKSHTSVKKIFINIKFEASEESFMLQLDPQDLPVVLMKSALRKKATVFRSAKQEKPEDY
TLQVNGRWEFIYGKYPLCRFKYIFSCLYGGLTPHLTMVHHSTISKYQEEQGGLSNQVSKS
RSQSKPPPLPLKKQNTSSLWSIHEPFHINLLHGTRVNADESMKLVVQAGLFHGSELLCKV
VTSSEVNVCSDPVWDQKLSFDINLCDLPRMTRLCFALYGVLDKPRKQRSTKKKNKKADCP
LAWVNTMLFDYKDQLKTGEIFLSTWPSAPDDKGDLLNPMGTVERNPNIDSSAALFIRFPS
FRPYPLYYPPLEKLNEVNGEKAVATKEEHLKLKEIVDNKNHTEFFEDEKELLWKLRGEVR
ANYPESLSKLLLITKWNKHDEVAQIVALLRKWPDLPALHALELLDYSFPDPHVRSFTIRC
LRKLRDEELFQYLLQLVQVLKYEPYLDCDLTTFLLERALSNKRIGHFLFWHLRSELHVPS
VSLKFGLILEAYCRGSIYHMKSLMKQNEALSKMKALNDFVKSGCQKSASRSQITEDMKLC
IKQDTYMEALSGVVSPLNPSIILSEICTDRCKFMDSKMKPLWLMYKNKCVQSDTLGIIFK
NGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQR
NKSNSAATAAFNKDALLDWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRENGQLFHIDFGHFLGNFKAKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREC
CEQAYKILCRNGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGRCEEEALKNFKVKF
NEALRESWKTKVNWMMHTFAKDNR
>A0A8C5PBY6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptobrachium leishanense|TrEMBL
MPPAVLDPMDIWAVDAQLHSEISVDVLLPTGIYVQMEVRRDASISHIKQLLWKHAPSYPL
YHLLLEMDSYMFECVNQTAVHEELEDETRRLCDVRPFLPVLKLVSRNCNPAEKLDSKIGV
LIGKGLQEFDALNDNEVKEFRSKMRKISEDKAQSLLRLTWMEWLKCTFPPELEPCVQENI
QDKLYSGNLVVAIHFDNCQDVFSFQVSPNMTPTKVNELAIRKRLTIHGREEEEVDPEDYV
LQVSGRQEYVFGDHPLIQFQYIKSCVMNKSLPRLILVECCNIKKMFDQEISAVELAVKRK
TTGPPLPLPPKTRASTISQSVWSLLEPYKITLIKGSKLSTEDTTVVVRAGLFHGTELLCK
PMSAELSGKSDSLWNAPVEFEINVCDLPRMARLCLAIYTVDKTQKKKGNKTGNPKYQTIK
KAGKMHYPVAWVNTMVFDYKGQLKAGEHVLHGWSSFPDELEEMLNPMGTVRTNPYIENAT
ALHIKFRDHAKAVYYPPFDKGRGGKKFNIELKEIMERDPLCQLCENEKDLIWTLRYDCRE
NFPCSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPRDALELLDFNYPDQYVREYAVNCL
KNMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLQRALANRRIGQFLFWHLRSEVHISTV
SVQFGLLLEAYCRGSVAHMKVLSRQVEALNKLRTLNSLIKLNAMKQSKVKNKESMHACLK
QNAYKEALTDIQSPLNPSVTLSELVVEKCKYMDSKMKPLWIVYSNRGFGGESMGIIFKNG
DDLRQDMLALQLLRLMDMLWKESGLDLRIVPYGCLATGDRCGLIEVVSAAETIADIQLDC
SNLAAAAAFNKDALLNWIKEFNAGDDLERAIEEFTLSCAGYCVATYVLGIGDRHNDNIMV
RKTGQLFHIDFGHILGNFKSKFKIKRERGPFILTYDFIHVIQQGKPGNTEKFGRFRQYCE
DAYLILRRNGNLIITLFALMLTAGLPELSSVKDIQYVKDSLALGKTEDDALKQFRQKFDE
ALKESWTTKVNWMAHTVRKDYNKS
>R0LBG6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos|TrEMBL
KMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLY
QLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGF
AIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPK
HIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQL
KLCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPL
DTFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTG
IYHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEH
CPLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDW
FSNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDP
LSEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAM
ELLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDIL
KQEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C3L980|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysolophus pictus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRMTSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKDRCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A822GMP7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ranitomeya imitator|TrEMBL
MPPTVSDPMDFWADDTQLSPKVSVDILLPTGIYVQMKVPRDASISQIKQLVWKDAETYPL
FHLLLEIESYRFQCINQTAVHEELEDESRRLCDVRPFLPVLKLVTRSCNPADKLDSKIGV
LIGKGLHEFDALKDNEVKEFRSKMRKISEDKIQSMLSLTWMEWLKCTFPPELEPAGQHLG
QDNIQDKLFGGNLVVAVHFENCQDVFSFQVSPNLTPIKLIELAIRKRLTIHGREDEDVDP
EDYVLQVIGRLEYVFGDYPLIQFQFSQLRCIEKKPPRLTLVECCNIKKMFDQEMSAIELA
VRRKPSAPPLPLPPKTRMVSKSVWDLNETYKITLIKGSKLNTEDTVRVVVRAGLFHGTEL
LCKSFMTSEIAGKNDHLWNETLEFDIYVCDLPRMARLCLAIYAVLDKTKTKKNIKASNPK
YQTIKKAGKVHSPVAWVNTMVFDYKGQLKTGEHVLHGWSSFPDELEEMLNPMGTVRTNPF
TENATALHIKFTEYSKVGIYYPPFDKILEKAAEIARHSDSLNMSGRGGKKFNIELKEIME
RDPLCQLCENEKDLIWTLRYDCRENFPCSLPKLLLSVKWNKLEDVAQLQALLQIWAKLPP
RDALELLDFNYPDQYVREYAVNCLKTMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLER
ALANRRIGQFLFWHLRAEIHNPAVSVQFGLLLEAYCRGSVAHMKVLSKQVEALNKLRTLN
GLIKLNAMKQSKGKNKETMHACLKQNAYREAISDVQSPLNPSVTLSDLVIDKCKYMESKM
KPLWIVYSNKGFGGENTGIIFKNGDDLRQDMLALQLLRLMDMLWKESGLDLRIIPYGCLA
TGDRCGLIEVVSAAETIADIQLDCSNLAAAAAFNKDALLNWIKEYNAGDHLEQAIEEFTL
SCAGYCVATYVLGIGDRHNDNIMVRKTGQLFHIDFGHILGNFKSKFKIKRERGPFILTYD
FIHVIQQGKPGNTEKFGRFRQCCEDAYLILRRNGNLIITLFALMLTAGLPELSSVKDIQY
VKDCLALGKTEEEALKQFRQKFDEALKESWSTKVNWMAHTVRKDYKS
>A0A673AXP4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
MPPAMTDLLDIWVDHSPLAGHASDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRMSEERMQRVQMMTWMEWLQACFSPSIAPS
LHLYEDMLLSPLFFSSLTVFTFNLSFVYNKNMAVKKWLTTHGPEEEAWRGQYVLRVSHCL
EFLCGDHPLILYKYIRLCIQVKEPPHLTLVHTSTVKAMFDKEISAIGAVVSRKSSNPPLP
LPPKRRVPTVSPRKLECDLFKIVLVSGSKVNAEETAKVQVRAGLFHGTELLCKPAVSSES
SGRSDHTWKDSTLEFDIAVCDLPRMTRLCFAIYAVMDKVKKQKSTKNTHLNKYQTIRKAG
KVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATALH
IHFPEYSSHPIIFPPFDKILEKAAEIARASDCAPMGRGGKKFHIELKEIMERDPLSQLCE
NEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDF
NYPDQYVREYAVGCLSDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLQRAQGNRKIGH
FLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIK
NARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNILLVEKCRYMDSKMKPLWIVY
NNKLLGGDTRGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRAGL
IEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALERAIEEFTLSCAGYCV
ATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQ
GKTGYTEKFGSFRQYCEEAYLILRKNGTLFITLFALMLTAGLPELTSVKDIQYLKDSLAL
GKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A851DM97|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Todus mexicanus|TrEMBL
MPPGIFCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLDTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWTAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRPAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDLVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGRCSESNAFFLPYFQLFHIDFGHFLGNFKTKFGI
NRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAG
LPELSCSKDIQYLKDSLALGKTEEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K4S9F6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Columbina picui|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTADFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVV
>H2YGB0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ciona savignyi|TrEMBL
VPLKMSSSAGMYAYEEESIYDEWGYHNSLNVSVDFFLPTGIYIPLDIPRNYTIKQVKHVL
WEEAIHYPLFSKLLNPESYIFTYITSFGLTEEIVDELRHLSEFDIFHELPVLKLVQSQGN
IAEKRVIQEINHLTCIKNHESSSFRKDMREMAIQVSKQRDALHWKELIQQHFPPTIIPYL
NDSTHYLKDFGLIQLTVENKVMYTIKINPGWTTDTLTREALAAWRQKTKSRLPSDNDDDY
VLKGGGKEYLVGNHPIYMFKYILKKCYFSHFFSHFFDVFCESISICLSVDDLNKTDSSSF
QNNLAPPVPEKHRPVWSLWQLDVMFKLRVIRAGNVNAAQERDKKLVIHIGLYHGSETLCP
TTYTKEPVKETAAGNEYQWDEECFFDINAVNLPRNAMLCFAVCSSKRGVGGKTKKDKKVI
SNCTGPQDGNQKYIQAATPIAWVNMMVFDFKRFLKAGLYRLNCWPVNLDNLDSNNLFPRG
GLMTNPDVEQATFIEIAMTEYQAAIMYPSLPEVLEEAARQAVVRESNLMTSAASKLHMTQ
LEEVIRKDRFDDLYDDDKSLLWRLRIDCREHFPDALSKVLASANWSSYKSVAMVQAMLNS
WKPLSPEHAMELLDSQYADEHVRDFAVKCLESLRDDELQQYLMQLVQVLKFDSYLSSSLV
RFILRRAWNNRKIGHFLFWHLKSEISQKTLNLRFSLILEAYLYGNLPHMKTLCKQHEALN
KMRTLNDRVSVKGAEFSPKDIKVRARQALKDTANQDSFREALTSVECPLEPNIDMQELLV
DKCKVMNSKMRPLWLVFKNSDMQDGSIAVIYKNGDDLRQDMLTLQTISIMDVLWKSEGLD
LRMIPYGCLATGEGTGMIEVVTHANTIANIQKTRGGKMAAFRHQTLIEWLEQNNTTKSEF
DQAIENFTYSCAGYCVATFVLGVGDRHSDNIMVTEKGQLFHIDFGHILGNFKTKFGIKRE
RVPFVLAHDFVHVINKGKNNNKADFDKFRKLCDNAFCILRRKGYLFITLFALMVHSGLPE
LNSLDHLEYLRETLALHLTEQKALQQFRSKFNKALTDAWATSVNWFFHNVTRDNT
>A0A8J5ZQB6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Galemys pyrenaicus|TrEMBL
VARGMELENYEQPVVLREDNRRRRRRMKPRSTVASLSSMELIPIEFVLPTSQRNSKTPET
ALLHVAGHGNVEQMKAQIWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVV
QTLDCLRYWNVLHRSPGQIHVVQRHAPSDETLAFQRQLTALIGYDVTDISNVHDDELEFT
RRRLVTPRLAEVAGRDPKLYAMHPWVTSKPLPEYLSKKIINNCIFIIIHRGTTSQTIKVS
ADDTPDTILQSFFTKMAKKKSLMNIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHC
LKNGEEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWD
CDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTDEVLWNVWLEF
NIKIKDLPRGALLNLQIYCGKAPALSGKASAEAPNSESKGKAQLLYYVNLLLIDHRFLLR
HGEYVLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTP
DPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSV
KWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLENLEDDDV
LHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVI
LEAYLRGCGMAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVVSQLKQKLENLQT
LNLPKSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGD
DLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTV
GNTGAFKDEVLNHWLKEKCPIEEKEVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKE
DIEYIRDALTVGKNEEDARKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A7K6WSZ4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Steatornis caripensis|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQITDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMVEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWVRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKGKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIVQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVVEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A672LA84|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDGTRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYSMPLEAGSLE
NLIDKHEGIIKITMHYDQSQVSSVNLVLTELMDQALKKWQTTHCPEEDIGFRSDYVLRVS
GKLEFLFEDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIGSVLARKTSNP
PLPLPPKKRLPTASTLFPALQLMQGVLSFAYLAVRAGLFHGTELLCKTAVSSESSSRSEH
VWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKHILFSTHIP
VLKLTVLCVMGDYQNNIWLSHAPPTPSLIFILSNRGFDNPHSPPPIQALIHTYELIMCFG
RGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDM
TQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVYCLRDMSDDELLQYLLQLVQVLRY
EPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMFMPAVSVHFALILEAYCRGCIPHIEV
LKKQVEALSKLKAVNELIKFGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNI
LLAGIKCKYMNSKMKPLWIVYNNKLLEGDTVDIIFKNGDDLRQDMLTLQILRLMDLLWKE
AKLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKN
SGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKF
GIKRERVPFILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLT
AGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A672M2R1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSAELPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKITHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDERHQA
>A0A226NWE8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Colinus virginianus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMLLLE
IAGNCTVEQMKAQIWMRAMEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGHHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNVWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGN
YKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAYLALRHHTNLLIILF
SMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDKGWTVQFNWFLHLV
LGIKQGVEKHSA
>A0A7L1IU05|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Smutsornis africanus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAVEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A672HFH5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salarias fasciatus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKIFYTILSSFFFSPKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLKMCVQEYQG
KYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMDNFTMPSYA
RRISTATPYMNGETATKCLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGIYHGGEQLC
DNVNTQRVPCSNPRWNEWLNYDMYIPEIPRAARLCLSICSVKGRKGAKEEHCPLAWGNIN
LFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSCPVKFPD
MTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNDQLRQVCNRDPLSEITEQEK
DFLWRHRHDCTNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNFPD
PMIRDFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFF
WHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLKQEKKDEAQ
KVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWENPDM
MSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLI
EVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRSCAGYCVAT
FILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGT
QECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLAL
DKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQQAMK
>A0A673TCX9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Suricata suricatta|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLLERPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMREEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSAPDEKGELLNPAGTVRSNPNTESAAALVICLPEVSP
YPVYYPALDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPDLPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMR
QETYMEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWLMYSNEEAGGDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGYC
ERAYTILRRHGPLFLHLFALMRAAGLPELSCSKDIQYLKS
>A0A7N8XUL0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MTPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFAEARKYPLHH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRTILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
ISSKLDKGRLIVSIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLH
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIMGRLPHLMLVSKDSLYSQLPAS
GFVTPSYRYSTTVQVWRGGDGPPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFSWF
NQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAADVEQLRSVCSKDPLY
ELSEQEKDFLWRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESALELLD
CNFPDPMVREFALRCLVQGLSDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRI
GHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQEK
KDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNW
ENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGD
CVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIRDKNRGEAYDRAIDLFTRSCAG
YCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIV
ISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQTFDDIAYLR
KTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMHAGKS
>A0A7N8XQ09|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIQSTSLLQWTYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQEAL
DYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A8K9G9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLCRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKPLSAEKYDVSSQVISQLKQKLENLQNSQLP
ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>Q4LE51|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
TMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLH
QLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGF
AIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPK
HIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQL
KLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPM
DCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTG
IYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEH
CPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDW
FSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDP
LSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAM
ELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDIL
KQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A2K8FKQ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSAQTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLREALDRAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERF
RGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFR
VKFNEALRESWKTKVNWLAHNVSKDNRQ
>W5UKI9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ictalurus punctatus|TrEMBL
MPPAMTDQLDVWADPILDGNDQVAVDFLLPTGIYIQMDVPRESTIHQIKQMLWKQAQVYP
LFSLLGEMDGHIFECVNQAAVHEELEDESRRLCDVRPFLPVLRLIIRNCGRAERLLDSKI
GVLIGKGLHELDALQDQEVKDFRSKMQRISEEKMQSVQMMSWAEWLQSCFSPQIEVAPVD
GLCDRNEGFIKITMHFNQSQDTTSIKVPLSCTVHELMNQALRKWLTTHGLGEDEDCIGNY
VLRVSDKLEFLFGEHQLMYYRYIRSCLLSQESPHLTLVHCDIVKAMFEHEISSIGAVLAR
KSSNPPLPLPPKRRGPSQLHTCIWEVQSLFKITLVKGIKVNAEETAKVQVRAGLFHGTEL
LCKPAVSNESSGRSEHIWNRTLEFDISVCDLPRMARLCFAIYAVMDKVKKQKSTKNMQMN
KYQTIRKAGKVHYPIAWVNMMVFDYRGQLKTGDIILHTWSSFPDELEEMLNPIGTIQTNP
YTENATALHIRLTEYSVNPLTFPPFDKILEKAADIAGSTDSISIGRGLKKFYIELKEIME
RDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHDDMAQLQALLQIWPKISP
RDALELLDFNYPDQYVREYAVSCLQDMSDEELLQYLLQLVQVLRYEPYYDCALSQFLLQR
AQTNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALGKLKAVN
ELIKLGTIKSKNKTKEAQLKEAMMKCLRQTGFIEILSDLHSPLNPQILLADVNVEKCRYM
DSKMKPLWIVYNNKLLLGDTLGIIFKNGDDLRQDMLTLQILRLMDMLWKEANLDLRIVPY
GCLATGDRTGLIEVVSSADTIANIQKNSSNMAAAAAFNKDALLSWLKDKNPGEALEKAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFI
LTHDFIHVIQQGKTGNTEKFGSFRQYCEDAYLILRKNGNLFITLFALMLTSGLPELTSVK
DIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAHPS
>A0A8C0LET4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus dingo|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A4X1V6I2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLDCLRYWKVLH
RSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRLVTPRMAEVA
GRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDTPGTILQSFF
TKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNGEEIHLVLDT
PPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGID
IPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALL
NLQIYCGKAPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHRFLLRHGEYVLHMWQLSG
KGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPN
QLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQQEIVAKTYQ
LLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQNKRI
GHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIDMLQKVTIDIKS
LSAEKYDVSSQVISQLKQKLENLQNLNLPQSFRVPYDPGLKAGALVIEKCKVMASKKKPL
WLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCIS
TGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLSHWLKEKCPIEEKFQAAVERFVYS
CAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDF
LFVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYI
RDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A8D0PKK6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPGVDCPMEFWTKEENQSVDVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKLVVQAGLFHGNETLCKTVSSSEVSVCSDPVWKQRLEFDINVCDLPRMARL
CFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKG
ELLNPAGTVRSNPNTESAAALVIFLPEVAPHPVYYPSLDKILELGRHGEHGRFTEEEQLQ
LREILERRGSGELYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNRHEDVAQMLYLLCS
WPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELT
KFLLDRALANRKIGHFLFWHLRYSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEAL
SKLKALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDPSPAPDGCAPGSV
EQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGL
DLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGE
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGIN
RERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYAILRRHGLLFLHLFALMRAAGL
PELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K8Y5C4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eubucco bourcierii|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEIILLE
IAGNYTVEQMKTQVWMRAIEMSQSTDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSEMDFVLRICGRDEYITGETRIKDFQWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVVWNIWLEFDIKI
KDLPKGALLNLQMYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNILLIDHRFLLRT
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKDNSMAISIVLDKYCHPVALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIITTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTTLSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKEKCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVRAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGRSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8B7PYS0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hipposideros armiger|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRLPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYCHAGLSNRLARDNELRENDKEQLRSICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRTGRRKVSI
REMVKRAGRPEMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWL
KDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHK
KKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINL
FSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHT
IKQHALN
>A0A341CAB4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neophocaena asiaeorientalis asiaeorientalis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A6G0IWG6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Larimichthys crocea|TrEMBL
MPPAMTDLLDIWAAHSPLAGHALDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRAKMFRMSEERMQRVQMMTCTEWLQACFSPQLEPA
AGPAISDGVNDRQADLKVTIHFNQSQDSASLKVPSSCTPTELMEMAMRKWLTTHGPEKEP
WRGQYVLRASHCLEFLCGDHPLSQYKYIRTCIQAKESPHLTLVPTSTVKDMFDKEISAIG
AVVSRKSSNPPLPLPPKRRVPTQVQTCVWDVSSSFKIVLVNGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESSGRSDHTWKDSTLEFDLSVCDLPRMTRLCFAIYAVMDKVKKQKST
KNAHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHSIIFPPFDKILEKAAEIARASDCAPMGRGGKKFHIE
LKEIMERDALSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSNEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAQRNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALS
KLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGI
NVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAS
LDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSG
DALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEDAYLILRRNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7L1XRX0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Thinocorus orbignyianus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKNTKVPEMVLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKVKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISVVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIGTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A0S7GRM7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poeciliopsis prolifica|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRNASGPHSRALYVYPPNVESTQELPKH
IHSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLTRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEASSKSLWSINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLPYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMNAVEDHANWIISRELGFNFNLSVNHSGTQQSSRAARDHALTESDSEQMRQL
SNRDPLSEITEQEKDFLW
>A0A6P5BD39|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos indicus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C0TWG2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNDFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPNDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKNI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSLQALLQIWPKLPP
REALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLER
ALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLN
SLIKLNAVKLNKAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKM
KPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLA
TGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTL
SCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYD
FIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>G3R2C2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gorilla gorilla gorilla|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQVCILTINLPEKIFISFIKIICIYFILLQHVWEN
NNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCKTIVSSEVSGKNDHIWNEPLEFDI
NICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFK
GQLRTGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHVKFPENKKQPYYYPPFD
KIIEKAAEIASSDSANVSSRGGKKFLPVLKEILDRDPLSQLCENEMDLIWTLRQDCREIF
PQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQ
MSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEVHIPAVSV
QFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQS
AYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDD
LRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSN
VAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKK
TGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDA
YLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEAL
RESWTTKVNWMAHTVRKDYRS
>A0A852L814|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Centropus bengalensis|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSTLSSMELISIEFILPTSNKHTKVPEMLLLE
IAGNCTVEQMKAQIWMRAIEISQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQRQQPSEAVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKISNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGVSTKTNLQSHESPNSDSKCKTQLLYYVNILLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPRAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLDDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C4DLN7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MTPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMLKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYNKQLTLGVHVSHDSLPEQLIAESIRKKSRSMHLSPQQLRLCVQEYQGQYILKVCGCDE
YLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPASGFVTPSYSRRTPQPSPCPG
GGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVP
CSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTDILV
SGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFSWFNQTVVFPDEQQIEEHAN
WTISRELGYNYCHGLSSRLACDSSVSAGDAEQLRSLCSRDPLYELSEQEKDFLWRHRHYC
VNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESALELLDCNFPDPIVREFALRC
LVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFFWHLKSEMHNK
TVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQKTQMKFLVEH
MSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFTNNE
IIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVKNSFTIM
QIQCKGGLKGALQFNSNTLHHWIKDKNRGEGYDRAIDLFTRSCAGYCVATFILGIGDRHN
SNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQESTKTKEFE
RFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKSQQEALEY
FTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A8C4HSQ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MLFILVTQILSRIYLIESNGDDKNTPCGFVLLWKQAQSFPLFPALGEMESHMFECVNQAA
VHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLDSKIGVLISKGLHELDGINDQEVK
DFRSKMFRMSEERMQKVQMMTCMEWLEACFSPQLEPAPGTAITDGLNDRPADLKVTIHFD
QSQVRVCSPVFTPIDLMELALRKWLTTHGPEEEAWRGQYVLRVSHCLEFLCGDHPLIQYK
YIRTCMQAKESPHLTLVHTSAIKAMFDKEISAIGAVVGRKSSNPPLPLPPKRRAPTVSPV
ECVPFKIVLVNGSKVNAEETAKVQVRAGLFHGTELLCKPAVSSESSGRSDHTWKDSTLEF
DISVSDLPRMTRLCFAIYAVMDKVKKQKSTKNHYPIAWVNTMVFDYKGQLKTGDIILHCW
SSFPDELEEMLNPIGTIQTNPYTENATALHIHFPEYSSHPIIFPPFDKVRQLSVIVLSVP
YSPYFHIELKEIMERDALSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMA
QLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMRLTYELSQYLLQLVQVLRY
EPYYDCALTHFLLERAQRNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEV
LKKQVEALSKLKSVNELIKLGTIKNARKAKEAMLTKEAMMTCLRQSGYSETLSDLHSPLN
PNVLLSGINVEKCRYMDSKMKPLWIVYNNKLMGGDTLGIIFKNGDDLRQDMLTLQILRLM
DLLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLN
WLKERNTGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILG
NFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITL
FALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHN
VAKDNRS
>A0A7K7SWQ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sapayoa aenigma|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQVWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPTEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSAKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISVVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVRAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A674ES60|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHEVFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKCPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGESSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRYYRHTTHMGDSLWLCLSPRWNEWLTYDMYIPDIPRAAR
LCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGV
TGSNPNKETPCLELEFDYFSSPVKFPDMTTVEGHANWTISRELGFNYCQSGQSNRVARDH
ALTDSDNEQLRQVCNRDPLSEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVA
QMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKY
EQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKH
LSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQL
GNIRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIME
NIWQNQGLDLRMLPYGCMSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWL
KDKNKGEMYDLAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHK
KKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINL
FSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHT
IRQHALN
>A0A667X3X7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
PHDEEPVVLREESRRRRRKKAITPSSCASMDQITVEFVLPSAARGGSGPDTLLLEVAANW
TVEQVKAQVWLRAVASNLCPDFYQRFSPDHCILLYQKKGSVCEIYDKHQVFQTLDCIRYW
RALKKEVGRIQLVPRPQPTDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPRR
IELSERDAKLYSTDPWLTDRPLTEHLLSKVSNGHILLVIHVGSNSQTIKVSIDDTPVLAS
FFTKTANKKALLGIPDSVCEADFVLRVCGREEYLYGDKPVQNFHWIRQCLKNGEEIHLVL
ETPPDPALDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVLG
IDIPSLPKNPELTVFVEASIFHGQQLLAQERTTSKPLSEEVLWNCWLEFNIRIRDLPKGA
RLNLPASGHWSVKEPETCLPDWKTKSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPEKSE
ESSSSVNADKLTSATNPDKASSMAVSVLLDRYCFPVVLPKSREAGRDAAAPDEAEGGERG
QREMPNHLRKQFEAIVATDPLHPLSPEDKELLWHFRHECMRHPRAYPKLLSSVRWGKQED
VLITHRLLERSTAWDSSSRLDVGLAMQLLDCHYSDAQVRSMAVRKLETLGDDDVLRYLLQ
LVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIVQSMHYQQRYAVLLEAYLR
GCGEAMLQDFRKQVEVTEALQRVTREIKAMSADKYDVSAQVVFQLRQKLETLQSSGLPDS
FRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSRDAIGIIFKDGDDLRQDM
LILQILLIMESIWETENLDLSLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAF
KDEILHQWLRDRCVSEDKKLCCVCVCVCVCVCVCVCVCVCVCAGNLFHIDFGHILGNYKS
FMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFHKFQDVCVKAYLALRHHTNLLIILFSMM
LMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQINWFVHLVLGI
KQGVEKRSA
>A0A667WL31|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
TAEHLYPSAYCSDPHSMVWRNAATEPLFSALGDSDAYVFTCINQTAEREELEDESRRISD
VLPFMCVLRLVAREGDRVEKLTNTQISLLIGKGLHDFEAQKNHEVNEFRSKMRSFCEEKA
LERQLLPWHQWIEYSFPCELEPCSSLPESGNTKSKNTKKIFESFMLQQDPHDFPVSLMKN
ALKKKATVFRLVRQEPEDYTLQVNGRWDFIYGKHPLCQFKYIFSCLRNSQNPHLIMVHSS
TINKYQEEQGTMCSQVSKSGSLSRPPPLPLKKVRGHRLLPSSINRAAACRSVVLALNQAT
DFGSLEACCAGLFHGSELLCKVVTSSEVAVCSEPLWDQKLEFDINVADLPRMSRLCFALY
AVIEKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPGALNDLLNP
MGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPHDKVLNPKHLYLSLKEIMDNKNYTEFFE
DEKELLWKLRAEVRDRYPESLSKLLLITKWNKREDVAQMLSLLRNWPDLPALHALELLDY
SFPDPTVRAFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNKRIGH
FLFWHLRSEMHVSSVSLRFGLILEAYCRGNIYHIKVLSKQVNALGKMRALSDFVKTGSQK
MTAEDLKLCIRQESYLEALSDLLSPLNPSIILSEICADKCRFMDSKMKPLWLMYKNQWVQ
GDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKTGLIEVVKN
SDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEDKIDQAIEEFTLSCAGYCVATYVLG
IGDRHNDNIMIRETGQLFHIDFGHILGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNS
EKFERFRECCERAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEE
ALKNFKVKFTEALRESWKTKVNWMMHSLAKDNRP
>A0A673X9Q8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPAMTNLMDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQQVQLMTWSEWLQACFSPQLEPGGG
ATPVTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISA
IGAVVNRKSSIPPLPLPPKRRGPSVSHVCVCVCVQVRAGLFHGTELLCKPAVSSESSGRS
EHVWNSTLEFDITVSDLPRMTRLCFAVYAVMDKVKKQKSTKNAHINKYQTIRKSGKVHYP
VAWVNTMLFDYKGQLKTGDIILHSWSSFPDELEEMLNPIGTIQTNPYTENTTALHIHLPD
YNPHPILFPPFDKILEKAAEIAGSSDCLPMGRGGKKFHIELKEIMERDPLSQLCENEKDL
IWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQ
YVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLNRAQCNRNIGHFLFWH
LRSEMHMPAVAVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSK
TKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMDSKMKPLWIVYN
NKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLI
EVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKAIEEFTLSCAGYCVA
TYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQG
KTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALG
KTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A674ESZ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPRPSSGELWGMHLMPPSIMVDCLLPNGMILTLECTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDAEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVSIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A674C0W0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MVSIGHIGYEPCVCVCVLVSEPLYGALSDADAYVFTCINSTAEREELEDETRRLCDVRPF
MSVLRLVAREGDRVEKLTNTQISLLIGKGLHEFDSQKNHEVNEFRAKMRSFCEEKAQDRQ
RLPWYQWMEYSFSCDLEPCVSLAEPGGIKTKGTKKIFVNVKFEASDVSQEPQDLPMILMR
SALKKKATVFRSVRQEKPEDYTLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVH
HSTIVKYQEEQGCLGSQVSKSRSLSKPPPLPVKKVRGQSVNTRMSNSVSHVGSYYVCACA
CVYARVCVSQLVVQAGLFHGSELLCKVVTSGEVNVCSEPLWDQKLVFDISVSDLPRMSRL
CFALYAVIEKAKKPRSTKKKNKKADCPLAWVNTMVFDYKDQLKTGEFLLSTWPSVPGDLL
NPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPHFDKVHLILHTRFNSYSHQGGGKGLSI
LKEIVDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKLLLITKWNKHEDVAQMVAFLQK
WPDLPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQLVQVLKYESYLDCDLA
TFLLERALSNKRIGHFLFWHLKSEMHVSSVSLRFGLILEAYCRGNIYHIKSLWKQNEALN
KMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLLSPLNPSIKLSEICADRCK
FMDSKMKPLWLMYKNKWVQGDAVGIIFKNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMI
PYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEDKLDQA
IEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVP
FILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSS
FKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDSRL
>A0A3Q2YJL6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hippocampus comes|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESSYIFVGVTQEAEREEFYDESRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRAILGVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPTNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKGPTALRHLRSPACLCPAPSLSDSV
>A0A8C3RXG8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelydra serpentina|TrEMBL
MPPGIYCPVEFWSKEENQTIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVRDPEVNDFRSKMRQFCEEKAAKRQQLNWMAWVEYNFPLQLEPLAKGPRT
GPLRVPNKNIFVNVKFESGGESFTFQISPKEFPVTLMSYAIKKQATVFRHQTVESPGDYT
LQVKGKCEYLYGNYPLYQFQYIRSCLHHGLMPHLTMVHFSSIIAMRDEQTNCTAHTPKMV
AKPPPLPKKKPIHESLWSLHQPFYIELVQGSKVNADERMKLVVQAGLYHGNEMLCKMVSS
AEVNVCSEPVWKQRLDFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQSNPNTESAAALVICFPSVTP
HSVYYPSFEQLLELGRNGEYTRAAPEDPEEKQQLREILERRSHTELYEHEKDLVWKMRYE
IRDQYPEALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFTI
NSLKKLTDDELFQYLLQLVQVLKYESYLDCELAKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSNYHMKVLMKQGEALNKMKALNDFIKVSSQKATKPQAKEMMHV
CMKQETYLEALSNLQCPLNPTIILAEVCVDQCTFMDSKMKPLWIVFSNEEAGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATFVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRD
YCEKAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C0IWN1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelonoidis abingdonii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVCPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWVINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMTVIEEHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSFTFHLLILLFNLPVWYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C4KNQ4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dromaius novaehollandiae|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWSINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K5LGQ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vireo altiloquus|TrEMBL
MELEDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTCNKHTKTPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKISNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPCAKTNLQSHESSNSDAKFKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVLYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A151M614|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alligator mississippiensis|TrEMBL
MTKSLANICSSRGPCGYDTIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAH
SYPLFHLLLEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDS
RIGVLIGKGLHEFDALPDPEVKEFRTKMRRISEEKNHSLVSLSWMDWLKHTYPPEQEPSI
PENFQDKLYGGNLVVAIHFDNCQDVFSFQVSPNINPIKLNELAIRKRLTIRGREDEEINP
SDYVLQVSGRLEYVFGDQPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCDQEMIAIEAA
INRKSSNLPLPLPPKKTRTATQLTQSVWDISNPFKIILLNGNKLNTEETTKVSVRAGLFH
GTELLCKPIVSTEVSGRSDHVWNETLEFEVNVCDLPRMARLCFAVYAVMDKMKTKKSTKT
MNTAKYQTIRKAGKVHYPVAWVNTMIFDYKGQLKTGDLILHSWSSFPDELEEMLNPMGTV
QTNPYAENATALHIKFQEYSKLPIYYPPFDKILEKAAEIAKSSDSAMAGRGGKKFYVVLK
EIMERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWT
KLPPREALELLDFNYPDQYVREYAVGCLKLMSDEELSQYLLQLVQVLKYEPFLDCALSRF
LLERALANRRIGQVLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLSKQVEALNKM
KTLNGLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHIERCKYM
DSKMKPLWIVYNNKMFGGDFVGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPY
GCLATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFI
LTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRRHGNLFITLFALMLTAGLPELTSIK
DIQYLKDSLALGKSEEDALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A2K5V7M8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca fascicularis|TrEMBL
MELENYEQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSMASDFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPAVSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDTCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8J4MYV7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eudyptula minor|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCMSGNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQKRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGNRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEVVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A091H7T7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Buceros rhinoceros silvestris|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIHSLVGLSWMDWLKHTYPPEQEAV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGREDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AVNRKSSNLPLPLPPKKTRTTISVWDISNPFKITLLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNT
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPISYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGNVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7L2AI37|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Heliornis fulica|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKSLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPEEFPITLMSYAVRKQATVFRHETVEKPEDYT
LQVNGKSEYLYGNYPLYQFQYIRSCLLRGRTPHLTMVHSSAIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNSGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKPKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSTAL
HPVYYPSFEQLLELGRNGEQPRTAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDTLEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKIKVNWLAHNVSKDNRQ
>A0A3Q1ETN1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acanthochromis polyacanthus|TrEMBL
MDGQQIQVSDEEPEVLREESRRRRRRKKAITSSSCTSMDQISVEFVLPTAARGGNGPDSL
LLEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQQFSPDHCILLYQKKGNVCEIYDKHQVFQ
TLDCIRYWRALKKDVGRIQLVPRPHPSEESQQYQSYLNCLIGYDVTDVSNVHDDELEFTR
RKLLTPRRIELSDRDPKLYSMDPWVTRKPLHEHLRTKINNSHILVVIHISTASQTIKVSI
DDTPTQVLASFFAKTANKRVLLGIPENKCETDFVLRVCGREEYLYGEKPLQNFNWIRQCL
KNGEEIHLVLETPPDPELDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDC
NRKFRVKVLGIDIPSLPKVPDFVVFIEASIFHGQQLLAQERTTSKSFSEEVLWNCWLEFN
IKIKDLPKGARLSLQGDASFCLSVNLSGKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWK
MPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDYGAAGEE
VEGGERGQREMPNHLKKQFEAIVATDPLHPLSPEDKELLWHFRHECMRNPRAYPKLLGSV
RWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDV
LRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVL
LEAYLRGCGENMLQDFRKQVEMTEALQKVTCEIKAMSDDKYHVTAQVVFQLRQKLETLQA
SGLPESFRVPYDPGLRAGVLLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGD
DLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVV
GSTGAFKDELLCQWLRDKCVNEEKFQQAVERFLFSCGGYCVATYVLGIGDRHNDNIMITE
SGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKA
YLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDDARHHLLDQIEICR
EKGWMVQVNWFVHLVLGIKQGVEKRST
>A0A8C6K2G8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Melopsittacus undulatus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GPFHIPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKTA
AKPPPLPKKKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWQQRLDFDINICDLPRMARL
CFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKG
ELLNPMGTVQCNPNTESAAALVICFPSVASHPVYYPSFEQLLELGRNGEQPPLSCDSHEQ
KLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISL
LQTWPELPVLNALELLDFSFPDRYVGSFAVNSLKKLTDHDVFQYLLQLVQVLKYESYLDC
ELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKILMKQGE
ALNKMKALNDFVKASSLKATKPQTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVD
QCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDL
RMTPYGCLSTGDKTGLIEVVMQSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDAL
EQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRE
RVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPE
LSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKNNRQ
>A0A0A1U2Z4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Entamoeba invadens IP1|TrEMBL
MSMRKTRTTFSVPRKTQVVDIDDSHKVRVIVKNGEKWIGLTFSPAGTTQMIIESIKAQHL
VPENEAFTFCLFNLPFYFNPEDPVAGGQIWKFCLAYGYRIVTTILPTKSTEKFLHVSKFL
EFLESTKINFFIIGKEYTAMLATMPDESRDFRASLARVIQEEVEWSENHSDKRTIEENEY
VYVESEPPIPNKMQKVKINGRYGNDLSMKTIAQSLSDTVCTVINSLYTKLFTMKPTLFDE
GSTANDFVLKVRGSNEFLVPKKNDGSEYTLCDFDYIRRCVAHNEPIDIVLYKRSKMYQYL
YDPEKLKMSKYFHMFVGNNYWGKTEKISLFLSQRGAMINFGIQIMGCGKLKMKPNDQRFL
SRIYFIASLHYGTRILSKPECSEVIEVIDGFVQISTPITILFDMLLSTLPKETRLIISVY
YTEAQLGSKGGENREHDICLSTVNCKLVDYNGYFMKGTFNVGMWENINPNPYAMCCENST
GRCKLIYRMIEFDKPVKMDTFIATKEELRRTLQQTNKLLPEHKDMYKAAVEADPLVSLTE
EEIRLLWIYRGLVMNTKPRALARLVSAVDFTKQDEVIELHRLLERWPLLEPTPALELLDF
RFPDEKVRLFALKCIDAMKDHELVDFLPQLVQALKFEIHHQSFLAFFLLRRALRNKNIIG
HQFFWFLKAEMHDNRVAERYGVLLESFLNGIEGYKTELYNEVNFQNELVVIANEVKNIAD
REEQKEYLRNGLVKLKYPEEMSLPLDSRFRVKKPVKNCGNVFSSKKKPLMLVLENVDPIG
NNITVIQKVGDDLRQDVLTLQMLQLMNNIWKSAGLDLRMLPYRCIATGDETGMLELVQDS
ETYGKIIADNEGTFRVFKEDLLTKWLKEQCSRPESKVTFDQAVENFVYSCAGYCVATYIL
GIGDRHSDNVMIRKDGKFFHIDFGHFLGNFKSKFGVKRERTPFKFTGHFAHVMGGRGAPN
FKLFEDLCLRAFACIRKQGSLFIYLFRLMLATGIPELQSEKDIEYMRNMFMFDKKEDEAR
EEFRQLIYKCLDAKSQTFNDLVHDYMHYK
>A0A6P7R3K8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus caroli|TrEMBL
MPPGVDCPMEFWTKEESQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLRVCNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYA
LQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHFSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMKLIVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGHITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMR
QETYMEALSHLQSPLDPSTLLEEVCSVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFK
NGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQL
NKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGY
CERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKF
NEALRESWKTKVNWLAHNVSKDNRQ
>G1SZP8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryctolagus cuniculus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVLLLACQSVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIV
VIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYIL
KVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRRIS
TATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVN
TQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDY
TDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVI
EEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPLSEITEQEKDFLW
SHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVR
AFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLK
SEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQM
KFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSEL
LFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVR
NSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILG
IGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECT
KTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTE
QEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3Q2GMD8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinodon variegatus|TrEMBL
MPPGKYGTQEEWDKEGEQDMDFLLPTGIFLKFPVSQNDTIRNIKKMVWKNASREALFCAL
GDPDLYVFTCINQTAEREELEEESRRISDVRPFMRVLRLVAREGDRSEKLTNAQISLLIG
KGLHEFEAQKNHEVDEFRTKMRTFCEEKAVERQNLPWQRWMEYSFPCELEPSPAASGSAK
SKHSKKLFINIKFESSDESFMLQQDCQDLPVALMKSALKKKATVFRSVRQEPEDYTLQVN
GRWEFIYGSHPLCQFKYIFSCMRNGQNPQLTMVHHSTISKYQEDQGRVGSQMYKTRSLSR
PPPLPLKKNTSSLWSINEPFYIHLLQGSRVNADEGMKVGVVSRRFSLTLLLNEMWRWLVY
QYVNFSCRSSQDCPIAWVNTMVFDYKDQLKTGEFLLSMWPSVPDDKSDLLNPMGTVEKNP
NVDSAAGLLIRFPNIRPHPLYYPPLDKIINPERNGETVFPPKDEYLRLKEIMDNKNYTEF
FEDEKELMWKLRAEVRDYFPECLSKLLLITKWNKREDVVQMVGLLKSWPELPAIHALELL
DYSFPDPAVRSFTIRCLKKLSDDELLQYLIQLVQVLKYESYLDCDLATFLLERALSNRRI
GHFLFWHLNILQGKHPPHQAFIQTGNSLVYYFRNEALGKMKALSDIVKTAQKMTVDDLKL
CIRQESYMEALSDLLSPLNPSVILFAICADKCRFMDSKMKPLWLMYKNPLEQADMVGIIF
KSGDDLRQDMLTLQMIRLMENLWKKENLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDR
HNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGKTNNSEKFE
RFREYCEQAYKILCRNGTLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEDEALKS
FKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A452VI53|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus maritimus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRVKKLVNSQISLLIGKGLHEFDSLHDPEVNAFRT
KMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGAGTLRVPNRALLVNVKFEGSEE
SFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYTLQVNGRQEYLYGGYPLCQFQV
SARSGRGPPSSLSLWSLEQPFCVELIQGSKVNADERMKVEGSWGRGMFSAQTRWLWSRGP
RMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGECCLYMWPSV
PGPPRRKGEANPNTESAAALVICLPEVAPYPVYYPTLDKVSPLAVQGLGGSRGCGAEDDC
LDPGHLLHCMELGRHGEPASPVRRDDELFRYLLQLVQVLKYESYLDCELAKFLLARALAN
RKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVK
VSSQKTTKPQTKELMHVCMRQETYLEALSNVQSPLDPSTLLAELVLFLPRRCPDLRQDML
TLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAA
FNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFH
IDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRR
HGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKT
KVNWLAHNVSKDNRQ
>A0A8C7XZ92|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias sinensis|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETCYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDFEVQDFRRNILNVCKDAVELRDANGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYSQLPTD
SFVMPSYCRRISTATSYMNGEAAPKSLWTISGGLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLNYDMYILDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYNHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEHF
SSPVKYPDMNAVEEHANWTISRELGFNYNTSGQSNRVARDHALTDSDSEQLKQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKFLADDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNRGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKGEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8B8XB89|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balaenoptera musculus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRAEVAQMYCLXKIGLNQTEQAMEL
LDCXYPDPMVRGFCFACLEKYLTEDKLSQYLIQLVQVLKYXQYLDNLLVRFLLKKALTNQ
RIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQ
EKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWL
NWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSI
GDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAY
IRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C7Z8P6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias sinensis|TrEMBL
FWCHVHFTMPPAMTDLVDIWAAHSPLDGQAPVHVTMDFLLPTGIYIQMEVPREATIQHIK
LLLWKQAKSFPLSSFLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVFRLVTRNC
GRAERLLDSKIGVIIGKGLHELDGINDQEVKDFRSKMQRLSEERMHRVQMMSFTEWLQAC
FSPQLEPSAGTAIADGANDWPADLKVIIHFDQSQDSTSLKVPSSCTPSVLIEIALKKWQT
THAPEEETNKDKHILRVSQCLDFLCGDHPLIQYKYIRSCLQAKESPHLTLVHINAVKAIF
DKENAAIGAVVSRKSSNPPLPLPPKKRAPTVQVRAGLFHGTELLCKPAVSSESSGRSNHS
LENNTLEFEISVCDLPRMTRLCFAIYAIMEKVKKKSYKNPHINKYQTIRKAGKVHYPIAW
VNTMVFDYKGQLKTGDMILHCWSSFPDELEEMLNPIGTVRINPYPENATALHIHFPDYGP
HPIVFPPFDKILEKAAEIAGSSDSTPIGRGGKKFHIELKEIMERDPLSQLCENEKDLIWT
LRLDCRENFPQSLPKLLLSVKWSKHEDMAQVSLVIDCCIFKPSAPDTFVLQGKCFHWKRI
SDYYYYGFLMFNDEIIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDA
LLNWLKERNSGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGH
ILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGRCVPLFHSCGSHVPIQVQDS
LALGTTQKPASPVQVHVTPYRCM
>A0A4Z2C291|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu bimaculatus|TrEMBL
MPPRPSSGELWGMHLMPPSILVECLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDCNGPHSRALYVYPPNVESSPELPRH
IYNKLDKGQIIVVIWVIVSPTNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
IFTIPSYARRISTATPYMNGETATKALWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLSYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEHF
GCPVKYPDMTIIEEHANWNISRELGFNYCHTGLSSRLARDNPVTDADNDQLRQVCTRDPL
SEITEQEKDFLWRHRQDCLNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIRPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8J1MN31|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus laevis|TrEMBL
MKKERLLWGNMLSSGMELDNYEQPVVLRDENHRRRRKMRPHSAASSVISMELIPIEFSLP
TSNRCSKVQETMLLEVAGNCSVEQMKAQVWMHAIEKSHNCDFYQMLTPDQFLLRYQKKGQ
WYEIYDKHQVIQTLDCIMYWKVLQKTVGKIHIVQKEKTSEEMIEYQKTLNYLIGYDVTDV
SNVYDDELEFTRRRLVTPRMIELSRRDARLYSMDPWVTSKPLPEYLCQRITSNSIFIIIH
KGMTTHTIRVSIDDTPDAILHSFFTKMAKKKSLLEISEENSELDFFVLRVCGRDEYIIGN
APIKDFHWIRQCIKNGQEIHLVLDKPPDASKDDVQKEEWPLVDDCTGVTGYHEQLTIEGK
DHEKIFTISLWDCNRKFRVKIIGIDIPVLPKNTELIVFVEGNIQHGQQVLSQRRTMCKPF
NEEVLWNSWLEFDIKIKDLPKGALLNLQIFCGKAPTVSNKSTVLSPESATSDSKCKNQLL
YYVNLLLIDHRFLLRQGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKETSMAISIIIV
QKLESLQDDDVLHYLLQLVQAVKFEPYHDSALSRFLLKRALQSKRIGHFLFWFLRSEIAQ
SMHYQQRFAVILEAYLKGCGKALLDDFTRQVKITEILHKVTMEIKSVSAEKYDVTSQVIT
QLRQKLEKLQNSKLPDKLPDSFRVPYDPGLRAGSLVVERCKVMASKKKPLWLEFKCSDTT
ALSNETIGIIFKHGDDLRQDMLILQILRIMGSIWEAESLDLCLLPYGCISTGNKIGMIEI
VKDATTIAQIQQSTVGNTGAFKDEVLSQWLKEKCPIEEKFSAAAERFVFSCAGYCVATFV
LGIGDRHNDNIMVTESGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKK
TSQYFNKFQVCV
>A0A1S3GQW0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dipodomys ordii|TrEMBL
MEFWTKEENQSVMVDFLLPTGVYLNFPVSRNANLSTIKQVLWHHAQYEPFFHMLSDPEAY
VFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVARECDHVKKLINSQISLLIGKGLHEF
DSLRDPEVNDFRDKMRQFCEEAVAHRQQLGWEAWLRYSFPLQLEPLARSLGAGTPKTPNQ
TMLVNVKFEGNEESFTFQVSSKDKPLALMACALRKKAKMFSQCLVEQPEDYALRVNGRHE
YLYGSYPLCQFQYICSCLHSGRTPHLTMVHSSSILTMRDEQSNPTPQVQKPCTKPPPIPA
KKPSLVSLWSLEKAFCIDLIQGSKVNADERMKLVVQAGLFHGNELLCKTVCSSEVSMCSE
PVWQQRLEFEINVCDLPRMTRLCIMLYAVVEKTKKARSTKKKSKKADCPIAWANLMLFDY
KNQLKTGECCLYMWPSVPGEKGELLNPVGTVCSNPNTKSASTLLICLPEVAPHPVYYPAL
EKILELGHHGERAHATEEEQLQLREILERQGSGELYEHEKDLVWKLRHKVQEHFPEALAR
LLLVTKWNKHEDVAQLHLTTSTPTPQMLYLLRSWPELPVLSALELLDFSFPDCHVGSFAI
KSLRKLTDDELSQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PSVALRFGLILEAYCRGCTHHMKMLMKQGEALSKLKALNDFVKVSSQKMTKPQTKELMHL
CMRQDTYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEETGYAGNMGII
FKNGDDLRQDMLTLQMIQLMDILWKKEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANI
QLNNSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFR
GYCERAYTILRRHGLLFLHLFALMRAAGLPDLSCSKDIQYLKDSLALGKTEEEALKHFRV
KFNEALRESWKTKVNWMAHNVSKDNRQ
>A0A665U9K1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MSPGKYGMQEDWEKDGVQEIMMDFLLPTGILLNFPVSRNDTIKNIKRMVWKNARSEALFN
ALGDSDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNHEVNEFRSKMRTFCEEKAQERQQLSWQQWMEYSFPCDLEPCCFPCGS
AKSKNTKKIFINIKFEACDESFMLQQDPQDLPEALIRNALKKKATVFRSVRQEPGDYTLR
CNGTWEFIYGNHPLCQFKYIFSCLRNGQNPHLTMVHHSTISKYQEEQGRMCSQVYKTRSL
SRPPPLPLKKQNTSSLWSINEPFYIHLVQGNRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIHFPNIRQ
YPLYYPPLDKICDLEKNGDTHISFFSGTKEEYLKLKEIMDNKNYTEFFEDEKELLWKLRA
DVREYYPESLSKLLLITKWNKREDVVQMVSLLRNWPDLPVIQALELLDYSFPDPAVRSFT
VRCLRKLSDDEILQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETH
VASVSLRFGLILEAYCRGNIHHIKLLAKQNEALGKMKALSDFVKSGSQKMTAEDLKLCIR
QESYLEALSDLLSPLNPSIILEEICADKCRFMDSKMRPIWLMYKNQWAQGDMMGIIFKNG
DDLRQDMLTLQMIQLMETLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNN
SNSAATAAFNKDALLNWLKSKNPEEKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMI
RETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTSNSEKFERFREYCE
RAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNE
ALRESWKTKVNWMMHSLAKDNRP
>A0A665V7V7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHHLLQEETSYILSEAER
EEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPEVQDF
RRNILNVCKDSVELRDATGPHSRALYVYPPNVESTQELPKHIYSKLDKGQIIVVIWVIVS
PNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQGKYILKVCGCDE
YLLEKYPISHFYLTDCSSRMPNLMLMAKDSLYTQLPTDNFVMPSYSRRISTATSYMNGEA
AAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQMCDNVNTQRVPCSNPR
WNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVANKMA
LNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSSPVKYPDMNAVEDHANWTISR
ELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPLSEITEQEKDFLWRHRHYCMNIP
EILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAMELLDCNYPDPMVRHFAVRCLDKY
LTDDKLSQYLIQLVQVLKYEQYLDNPLARHFFFWHLKSEMHNKTVSQRFGLLLEAYCRAC
GMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPL
NPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQ
IIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSN
TLHQWLKDKNKGEMYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFG
HFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECTKTKEFESLIPQPARAP
>A0A7K9J3X0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myiagra hebetior|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKSQIWMRAIEMSQTTDFYHEFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQAHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K6LSN8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Falcunculus frontatus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSE
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIVQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGRSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A4U5UQW8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Collichthys lucidus|TrEMBL
MPPGKYGMQEEWEKEGDQGIVMDFLLPTGIFLKFPVSRNDTIKSIKKMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEESRRICDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRSKMRTFCEEKAQERQMLHWQQWMEYSFPCDLEPCCSPPVC
ASAKSKNSKIFINVKFEASEESFMLQQDPQDFPVALMKSALKKKATVFRSVRQEPEDYTL
QVNGTWEFIYGKHPMCQFKYIFSCLRNGQNPHLIMVHHSTISKYQEEQGRMCSQAYKSRS
LSRPPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKAPWVNT
MVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFHNIRQHPL
YYPPLDKISDVEKNGDAPFATKEEYMKLKEIMDNKNHTEFFEDEKELLWKLRAEVRNHYP
ESLSKLLLITKWNKREDVVQMVSLLRNWPDLPGIHALELLDYSFPDPMVRSFTIRCLRKL
SDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVSLR
FGLILEAYCRGNICHIKLLTKQNEALGKMKALSDFVKSGSQKMTVDDLKLCIRQESYLEA
LSDLLSPLNPSIILAEICADKCRFMDSKMKPLWLLYKNPLAQGDMVGIIFKNGDDLRQDM
LTLQMIQLMENLWKKEGLDLRMIPYACLSTGNKMGLIEVVKNSDTIANIQRNSSNIAATA
AFNKDALLNWLKSKNPEEKLDKAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLF
HIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRGYCERAYKILC
RNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWK
TKVNWMMHSMAKDNRP
>A0A8J4XH74|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Clarias magur|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLVTIKHELFKEARKFPLHH
LLQEEASYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESSPELPKH
IFGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMD
TFTMPSYSRRISTATPYMNGEASSKSLWTINSNLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLMYDMYIHDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
TCPVKFPDMATIEDHANKIMSREMGYNYFQSGQSSRQARDHHIMEGDIEQLRQVANRDPL
SEITEQEKDFLWRHRQYCKNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLGRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNITSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGETYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A8C2AYY9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MKAFTSTSAVSTDHIAVEFVLPTTNKNSKYPDTLHLDVTGNWTVEQVKVQIWHRAVTTKL
CPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTLDCIRYWKALRKEVGKIHLVIRQQP
NEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRKLLTPRKIELADRDPKLYSMDPWIT
PKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDDTPVQVLQSFFTKITKKRAILGISE
DVSESDFVLRVCGREEYLYGNYAISDFHWIRQCLKNGEEIHLVLEHPPDPELDVVQKEDW
SQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRKFRVKILGIDIPVLPRNSELIVFV
EASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIKIKDLPKGARLSLQVSCGKAQTQTS
KENECKNKTRLLYYVNLLMVDHRSLLRQGEFILHMWKMPEKSEDNSSVNADKLTSATNPD
KNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERGQREMPNHLRKQFEQIIATDPLHPL
SSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEAVAITHCLLERSTVWDRSSHDVGLA
LQLLDCHFSDENVRTLAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALR
SKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGEAMLQDLRKQVEMTEALQKVTR
EIKQMSAEKYDVSIEQCKVMASKKKPLWLQFKRADPTTLSRDTIGIIFKDGDDLRQDMLI
LQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKD
EILSQWLSEKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHID
FGHILGNYKSFMGISKERVPFVLTPDFLYVMCTTGKKSSPYFLQFQNVCLKAYLALRHHT
NLLIILFSMMLMTGMPQLSSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQF
NWFLHLVLGIKQGVEKRSA
>A0A8C2AWA3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSMSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNDLGMNGEKTTKEEHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQRY
PESLPKLLLITKWNKHEDVAQMVSLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRK
LSDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSL
RFGLILEAYCRGSIFHIKSLIKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQD
TYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQ
DMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAA
TAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMISETGQ
LFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERSVHSKLVLFCS
LLPFLSHKKKQLSFYDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A8C1LSJ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLETESVE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDY
VLRVSCRLEFLLEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAIFEKEICTIGSVLAR
KASNPPLPLPPKKRTPTVRTLSVFPALQLIKGALSFVPLAIQVRAGLFHGTELLCKTAVS
SESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRK
AGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATE
LHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTIGRGGKKFYIELKEIMERDPLSQL
CENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELL
DFNYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKI
GHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKLGT
IKTKTKQAHLKEAMMTCLRQTGFIETLSNLHSPLNPNILLAGVHVERCKYMDSKMKPLWI
VYHNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHS
GLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGY
CVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVI
QQGKTGNTEKFGNFFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDS
LALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A8C1J9A2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGLCHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVA
QSGKSRSVKKILVNVKFEGSEETFVLQQDPQDLPMLLKRNALRKKSTVFRAAKQEKPEDY
TLQVNGRWEFIYGEYPLCQFKVSLKVTTSSRLHSYSTTLSDSRTHVFLNLILLFSYFFFC
IYILFYCNVKFLVVQAGLFHGSELLCKVVISNEVSVCSEPVWDQKLVFDIGVSDLPRMSR
LCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPDLLN
PMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKHMKLREIVDNKNYTEFFEDEKELL
WKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPH
VRSFTIRCLRNLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHL
RSEMHVPSVSLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQT
TEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCTDKCKFMDSKMKPLWLMYKNKYDHVG
IIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIA
NIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFER
FRECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNF
KVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A7L2DAK8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Catharus fuscescens|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTNAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYSMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSEVDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHEPSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GDYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQGI
>A0A3P8S2B9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amphiprion percula|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAYLKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWIISRELGFNYCHTGLSNRLARDNPLTDNDNEQLRQVGNRDPL
SEITEQEKDFLWRHRHDCINMPEILPKILLAVKWNSRDEVSQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQAAMN
>A0A0F7Z638|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crotalus adamanteus|TrEMBL
MELESSDEAVVMRDDNKRRRRRRMKPYCTANTFSSTELISIEFVFPTTSIVLDVATNCTV
EQMKAQVWMQAVEGHQTSEVFRKLTPDQFLLLYQKKGQWYEIYDKHQIMQTLDCILYWKV
LQKKVGKIHVIEKPSPSEEVQEFQRQLNYLIGYDVTDVSNVHDDELEFARRRLVTPRTIE
VSCRDPKLYSMHPWTTSKPLPEYLLSRIVNNTIFINIHRGTTSQKIKVGVDDTPEVILQS
FFTKMAKKKSLMNIPEDYSELDFVLRVSGRDEYIVGETPIKNFHWIRQYLKKGEEIHLVL
DEPPDPNQDEVQKEEWPLVDDCTGVSGYHEQLTIQGKDHERVFTISLWDCNRKFRVKVIG
IDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTTAKPFTEEVLWNVWLEFDIKIKDLPKGA
LLTLQIYCGKTPAPSTKGNLHSYDSPSSDPKYKTQLLYYVNLLLIDHRSLLRTGDYVLHM
WKIPGKGEEQGSINADKLTSATNPDKENSMAVSIVLDKYCHPIALPKHKIASDPQGDRAR
AEMPNQLRKQLEEIIATDLLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQELV
AETYQLLAKRDAWDQSALDVGLPMQLLDCNFSDETVRTMAVQKLEALEDDEVLHYLLQLV
QAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGC
GKAMLKDFLKQVQVTELLHKVTRDIKAASAEKYDVTPQVITQLKQKLERLQENKFPECFR
VPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTSLSSETIGIIFKHGDDLRQDMLI
LQILRIMALIWEEDSLDLCLLPYGCISTGNKIGIIEIVKDANTIAKIQQSTVGNTGAFKD
EILNQWLKEKCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITGSGNLFHID
FGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLRFQNFQDICVRAYLALRKHS
NLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKHEDDAKKYFLDQIEVCRDKGWTVQF
NWFLHLVLGIKQGVEKHSA
>A0A670J2Y3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podarcis muralis|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCLPNGMIVTLECLREATLLGIKHDLFKEARKYPLFH
LLQEESSYIFVGVTQEAEREEFFDESRRLCDLRLFQPILKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDPEVQEFRRNILSVCREAVETRGSAGPPSQALYVYPPNVESSPELPKH
VYSKLDKGRIIVTIWVIVSPNNDKQKYTLKTPHDALPEQVIAEAIRKKTRSMHLSPEQLR
LCVQEYQGKYLLKVCGCDEYLLEKYPLSQYKYMRNCITIGRLPHLMLMSKESLYSQLPAN
VFVLPSYARRSATSSHVNGDVPTKSLWSINSLLRIKILCATYVNVNIRDIDKIYVRTGIF
HGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDLPRAARLCVSICSVKGRKGAKEEHCP
LAWGNVNLFDYKDTLVAGKMALNLWPVPHGLEDLLNPIGVGGSNPNKETPCLELEFTWYS
HTVKFADATEIEEHANWAMSRELGLNYCMVGLSNRLARDSSLDESELEQLRSICNRDPLS
EITEQEKDFLWRHRHYCVNIPETLPKLLLSVKWNSRDEVAQMYCLLREWPLIKPELSMEL
LDCNFPDPVVREFALKCLVKGLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLTMKALTNQ
RIGHFYFWHLKSEMHSKPVSQRFGLMLEAFCRGCGMYLKHLNRQVEAMEKLINLTDILKQ
EKKDETQKMQMKFLVEQMRRPDYMEALQGFICPLNPVHQLGNLRLDECRIMSSAKRPLWL
NWENPDIMSELLFTNHEIIFKNGDDLRQDMLTLQIIRIMESMWQNQGLDLRMLPYGCLSI
GDCVGLIEVVKSSHTIMQIQCKGGLKGALQFNSNALHHWLKDKNKGEGYDAAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGVQECTKTKEFERFQEMCYKAYLTIRQHANLLINLFSMMLGSGMPELQSFDDVAY
LRKTLALDKSEQEALEYFTKQMNEAHHGGWTTKMDWIFHTIRHMPLSEAGHD
>A0A383Z5Q4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balaenoptera acutorostrata scammoni|TrEMBL
MCFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRALPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKAI
NPSKYQTIRKSGKVDYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRXXXXXPAVSVQFGVILEAYCRGSVGHMKALSKQVDALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYIEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDHSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A485NEH4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lynx pardinus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLLERPEDYA
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPVKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSAPDEKGELLNPAGTVRSNPNTESAAALVICLPEVSP
YPVYYPALDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPDLPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMRQGEALSKLKALNDFVKVSSQKTTRPQTKELMHLCMR
QETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDSSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGPLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A2K6T7K6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Saimiri boliviensis boliviensis|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLNGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRTKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKSTVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHFSSILAMRDEQSNPTPQVQKPR
AKPPPIPAKKPSSVSLWSLDQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISISDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLHMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
YPVYYPSLEKVSGAPPHEQLQLREILERRGCGELYEHEKDLLWKLRHEVQERFPEALARL
LLVTKWNKHEDVAQMLYLLCSWPELPVLGALELLDFSFPDCHVGSFAIKSLRKLTDDELF
QYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLILE
AYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMRQEAYLEALS
HLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSSGSVGIIFKNGDDLRQDML
TLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAA
FNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFH
IDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRR
HGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKT
KVNWLAHNVSKDNRQ
>A0A384BHM3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balaenoptera acutorostrata scammoni|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFXRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRQGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
GSVVKFPDMSVIEEHANWSVSREAGFSYSYAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A2K6SKL9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Saimiri boliviensis boliviensis|TrEMBL
MCFGFIMPPAMADILDIWAVDSQIASDGTIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDGLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
ISPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVVNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIIYHVWENNNPFQIILVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEVSGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKAKTKKSTKAI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSKYYLHKVAGKGKEQGKPPFMNDEELSQYL
LQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYC
RGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQ
SPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQM
LRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKD
ALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFG
HILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNL
FITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNW
MAHTVRKDYRS
>A0A4X2KQJ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vombatus ursinus|TrEMBL
MCLSFIMPPAMADILDIWGVDSQITSDGSVPVDFLLPTGIYIQLEVPREATISNIKQMLW
KQAHNYPMFNLLMEIDAYMFACVNQTAVYEELEDETRRLCDIRPFLSVLKVVTRSCDPGE
KLDSKIGVLIGKGLHEFDALEDPEVNEFRSKMRQFSEEKIQSLVGLSWMDWLKHTYPPEQ
EPSIPENLENKLYGGNLVVAVHFENCQDVFSFQVSPNMNPIKLNELAIRKRLTIRGKEDE
VDPYDYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPKLTLVECCNIKKMCEQEMIAI
EAAINRNSSNLPLPLPPKKTRLISNVWENTQPFQVILVKGTKLNTEETVKVHVRAGLFHG
TELLCKPVVSSEISGKNDRVWNEPLEFDINICDLPRMARLCFAVYAVDKVKTKKSTKTIN
PSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKAGDIILHSWSSFPDELEEMLNPMGTVQT
NPYIENATALHVKFPENKKQPYYYPPFDKSRGGKKFHAVLKEIMERDPLSQLCENEMDLI
WTLRQDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQY
VREYAVSCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFMLDRALANRRIGQFLFWHL
RSEVHIPAFSVQFGVILEAYCRGSVGYMKVLSKQVEALNKLKTLNSLIKLNAVKLNKAKG
REAMHTCLKQNAYREALSDLPSPLNPCVILSELYVEKCKYMDSKMKPLRIVYNNKVFGGD
PVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSE
TIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDQAIEEFTLSCAGYCVASYVLGIG
DRHSDNIMVRKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEK
FNRFRKCCEEAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEAL
KQFKQKFDEALRESWTTKVNWMAHTMRKDYRS
>A0A4X2MAV0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vombatus ursinus|TrEMBL
MPPGVDCPMEFWSKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVARQGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEDVAVRRQQLGWEAWMHYSFPLQLEPSARGVGA
GTLRVPNRTLLVNVKFEGNEESFTFQVSPNDFPLALMACALKKRATVFRQSAMERPEDYT
LKVNGKCEYLYGGYPLYQFQYICNCLHKGLTPHLTMVHSSSILAMRDEQSNLTAQAPKLR
AKPPPIPVKKPSSVSLWSLEQPFCIELVQGSKVNADERMKLVVLAGLFHGNEMLCKTVSS
SEVTVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWSSVPDEKGELLNPMGTVRSNPNTESAAALVICIPEVAP
HPVYYPTMEKILELGKNGEHGRFTEDELQQLREILERKVAAELYEHEKDLVWKMRHEIQE
QFPEALARLLLVTKWNKHEDVAQMLFLLGSWPELPVLSALELLDFSFPDRHVGSFAIQSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSNHHMKVLMKQGEALNKMKALNDFVKVSSQKTTKPQTKELMHVCMR
QETYLEALSNVQSPLNPSTLLSEVCVEQCTFMDSKMKPLWIVYSNEEAGGGADSHVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVSHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRS
YCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A668RT14|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MAPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLTTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYSKLDKGQIIVVIWVIVSPTNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPME
FFTMPSYARRISTATPYMNGETATKNLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLTYDMYIPEVPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHY
SSPVKFPDMSTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHDCINMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMVREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFESQWD
>A0A7K6CFG9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ptilonorhynchus violaceus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWRHAQYEPLYH
MLSDPEAYVFTCINQAAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQTPTKNIFVNVKFQSGGESFTFQISPREFPITLMSYAIKKQATVFRHETLQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKTA
TKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEPARAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPHLKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C9X3B0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MPPGKYGMQEEGDQEIMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNARSEALFSALGD
PDAYVFTCINQTAEREELEEESRRISDVRPFMGVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFEAQKNHEVNEFRAKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPECGSVK
SKNTKKIFINVKFEACDESFMLQQDPQDFPVALMKSALKKKATVFRSVRQEPEDYTLQVN
GRWEFIYGNHPMCQFKYMFLCLRNSQIPHLTMVHHTTISKYQEEQGRMCSQGYKTPFKPH
VIPSSNHFCAGLFHGSELLCKVVTTSEVTVCSEPLWDQKLEFDINVADLPRMSRLCFALY
AVIEKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNP
MGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPLDKVRILKRGKTFYISHFTSLTQLKRMK
LKEIMDNKNHTEFFEDEKDLLWKLRTEVRDHYHESLSKLLLITKWNRREDAVQMMSLLRT
WRDLPAIHALELLDYSFPDPVVRSFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLT
TFLLERALSNWRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIKLLSKQNEALG
KMKALSDFVKSGSQKMTADDLKLCIRQESYLEALSDLLSPLNPSIILTEICADKCRFMDS
KMKPIWLMYNPCTQEDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCL
STGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDRAIEEFT
LSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTY
DFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGMLFVNLFAMMKAAGLPELTSFKDIQ
YLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>H3AKC6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Latimeria chalumnae|TrEMBL
MPPGVYYTQSFWTEEESPDVNVDFLLPTGIYLNFAVPLRATISTIKELLWQQAQYEPLYH
TLNEPDAYVFTCINHTADQEELEDEQRRLCDICPFLPVLKLVAREGDRAEKHINSQISLL
IGKGLHDFDSLNDAEVNDFRTKMRQFCEEKASERQKLPWQAWMEYNFPRELEPSSELPET
GIIGKLSNNSIIVTVKSESSDDSFSFQVSPKAFPITLMQNALKKKATIFRQKNVESPKDF
TLKVNGRCEYIYGSYPLCQFKYIYSCIYSGLTPHLTIVHHSAIRSMQEEQASFNPQIPKT
RPKPPPLPMKKQTCTSLWNLDSPFSICLVGGRNLNADEAMKLVVQAGLFHGSEMLCKTVS
SQEVNMCSEPCWNQKLEFDINICDLPRMTRLCFVLYGVLEKAKKARSTKKKSKKAEKASC
FALEISICLSNITSQLLKSKTLTPLFWVGIPFLFSKLLECGTVACAENFILFTKQVTKYY
PLSKRHSSYMGDKTYFQHQQLKEILEKKNYTELYEHEKDLVWKLRYEIRDQYPEALARLL
MITKWNKHEDVAQMITLLQSWPELPTLNALELLDYSFPDRYVSTFTINCLRKFVDDELFQ
YLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHMPAVVLRFGLVLEA
YCRGNIHHLKALMKQIEALIKMKALNDFVKVGSLKTNKPGINEALHVYMKQDNYLEALSN
LQSPLNTNIILSDLCVERCKFMDSKMKPLWIVYSNERANGDLNGIIFKNGDDLRQDMLTL
QMIRLMDILWKQEGLDLRYKQLNIATDLLILCVEHRDFQARVKFNTMIHDTILYNNSVLQ
HLSLFSISVGRYLFYLKMLNILVFNFSFQLFHIDFGHFLGNFKSKFGINRERVPFILTYD
FVHVIQQGKPNNNEKFERFRNYCEKAYMILRTHGLLFVNLFALMKAAGLPELSCSKDIQY
LKDSLALGKTEEEAIKHFRLKFNEALRESWKTKVNWMAHNVKKDNR
>A0A437C288|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias javanicus|TrEMBL
MDRRSIQVSDEEPEVPHCRRRRRKKAITPSSCASMDQITIEFVMPSVARGGSGPDVLLLD
VAGNWTVEQVKAQVWMKAVTLNLCPDFYQRLSPDHCILLYQKKGTVCEIYDKHQVFQTLD
CIPYWRALKKGVGRIQMAPRPQPSDESLQYQRYLNCLMGYDVTDVSNVHDDELEFTRRKL
LTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVNNGHILVVIHIGMVSQTIKVSINDT
PSQVLESFFAKTANKRVLLGIPDDVCEADFVLRVCGREEYLYGEKPLQNFNWIRQCLKNG
EEIHLLLEKPPDPELDVVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRK
FRVKVLGIDIPTLPKVPELVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKI
KDLPKGARLNLQVICGKPAQTPACKGSSHYDNSAGTGSAEGKTKNRLLFYVNLLLVDHRS
LLRQGEFILHMWKMPEKSDESSSSINADKLTSATTRISPLPWPDCGAGEEMEGGERGQRE
MPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRQECMRDPRAYPKLLGSVKWGKQEDVLA
THRLLERSNAWDTSGLDVGLAMQLLDCHYSDSHVRSMAVRKLETLEDDDVLRYLLQLVQA
VKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGE
SMLQDFKKQVEMTMALQKVTREVKAMSADKYDVSAQVVFQLRQKLETLQSSGLPETFRVP
YDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQDMLILQ
ILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQRVVGSTGAFKDEI
LHQWLRDKCISEEKFQQAVERFLLSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFG
HILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFLKFQDVCVKAYLALRHHTNL
LIILFSMMLMTGMPQLTSKEDIEYIREALTVGCSEEEAQRHLLDQIEICREKGWMVQINW
FVHLVLGIKQGVEKRST
>A0A3P8PFX1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astatotilapia calliptera|TrEMBL
MAPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLTTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYSKLDKGQIIVVIWVIVSPTNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMD
FFTMPSYARRISTATPYMNGETATKNLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLTYDMYIPEVPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHY
SSPVKFPDMSTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDGDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHDCINMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMVREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A3P8PMW8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astatotilapia calliptera|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVMRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRSKMFRISEERMQQIQMMAFSEWVQACYSPQLEPA
AVTTITAGVNDAPVDLKVIIHFDQSQDSASLKVSLSCTPNELMEQALKKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKEAPHLTLVHTSTVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRRPPTQVQTCVWDVPKPFRIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSNESSGRSEHTWKDNTVEFEISVCDLPRMTRLCFAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHPIVFPPFDKILEKAAEMVSADCVSIGRGVKKFYMEL
KEIMERDPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVRCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTH
FLLERAQRNRQIGHFLFWHLRSEIHMPAVSVQFALLLEAYCRSNIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDIN
VEKCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRIVPYGCLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSNGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A6J2PBZ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cottoperca gobio|TrEMBL
MVPRPSSGELWGLHLMPPRIQVDCCLPNGMMVSLECLRETPLLSIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILCVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKESLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPARSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLAYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAGDAEQLRCLCSRDP
LYELSEQEKDFLWRHRHYCVKIPESLPKLLLSVKWNSRDEASQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQNLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A7J7F1L6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Diceros bicornis minor|TrEMBL
MLWKQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCD
PGEKLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYP
PEHEPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIEINELAIQKRLTIHGK
EDEVSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEM
FAIEAAINRNSSNLPLPLPPKKTRIISVHVRAGLFHGTELLCKTIVSSEISGKNDHIWNE
PLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKSGKVHYPVAWVNT
MVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIKFPENKKQPY
YYPPFDKIIEKAAEIASNDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQ
DCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYA
VGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVH
IPAVSIQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMH
TCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVI
FKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLR
>A0A4W3GJ58|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MQEEIQNDELPIVMREENKRRRRNMRANTTRGMQYYSLEQLSIEIILPTRNKRTAMHEKI
SLDIAGNYTVEQLKTKIWVKANGTSGSPEYYQKFSPDQFILLYQKKGQWYEIYDKQQVIQ
TLDCINYWKVLQKSVGKIHVVQKARSSDQSLQLQWDLNNLVGYDVTDVSNVHDDELEFTR
RTLITPRLTEVATRDVRLYSMDPWILSKPLPEYLLNKISGNNIFMIIHRGAVSLTIKVSI
DETPESILRNFFKKMAKKMSLLDMNESHSEEHFVLRVCGRDEYIVGDNPIKDFFWIRNCL
KNGEEIHLVLDLPPDPVLDEVQKEEWPLVDDCTGVTGSHEQLTLEGKDHEKVFTISLWDC
SQTFRVKIVGIDIPVLPRNTDVTVFVQASILHGQQILAQQRTPAKAFTEEVMWNMWLEFD
IKVKDLPKGARLNLQVYCGKAQALGSKALEDLWDSRSKNNMLYYVNLLVIDHRSLLRQGE
YLLHMWKIPNKGEEQGTIEADKLTSATNPDKQTSMAICILLDRYNYPIALPRSRQTDPEA
ERSGPEMHSQLRKQFEEIVSTDPLNPLSAEDKELLWHFRHECVKQPKAYPKFLSSVKWGQ
QDVVLKTHQLLQKQTAWASSPLDVGLALQLLDCRFSDEQVRTMAVQKLETFGNDDVLRFL
LQLVQAVKFEPYHDSALARFLLKRALGSKRIGHFLFWFLRSEVSESMHYRQRYAVMLECY
LRGCGQAMLMDFMKQVKVIKELQKLTKEIKNVTADKYDISSQAISQLRHRLEKLQSSGFP
ECFRVPYDPGLRAGALVVDKCKVMASKKKPLWLEFKCADPTSVSKDTIGIIFKQGDDLRQ
DMLIIQILLIMDSIWEMESLDLCLLPYGCIATGNKIGIIQIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCVIEEKFQSAVEKFVFSCAGYCVATYVLGIGDRHNDNIMITESGNL
FHIDFGHILGNYKSFLGISKERVPFVLTPDFLFVMGTYGKKTSPHFQKFQEICLKAYRTL
RHHANLLIILFSMMLMTGMPQLTSKEDIEYIRETLTVGKNEEEARTHFLEQIEICRDKGW
TVQFNWFLHLVLGIKQGVEKHSA
>A0A6P7PCD6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Betta splendens|TrEMBL
MPPAMTDLLDVWAAHSPLAGQAPAQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERQLD
SKIGVLIGKGLHELEAINDQEVKDFRSKVFRVSEERMQRVQMMTCMEWLQACFSPELVPA
AGTAPNDGVGDRTADLKVIIHFDQSQDSASLKVPSTYTPMELMEIALRKWRSTHAAEEGW
RGQYVLRVSHCLEFLCGEKPLLQYKYIRTCMQAKEAPHLTLVSTSTIKEMFDNEISTISA
VISHKSLNPPLPLPPKRRAPTQVQTCVWDVSAQFKIVLVNASKVNAEETAKVQVRAGLFH
GAELLCKPAVSSESSGRSDHTWKENTLEFDIFVSDLPRMTRLCFAIYAVMDKVKKQKSTR
NAHVNKFQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDNILHCWSSFPDELEEMLNPIGT
IQTNPYTENATALQINFPEYSSHPIVFPPFDKILEKAAEIVGSSECASMGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLCPRDALELLDFNYPDQYVREYAVRCLREMSDDELSQYLLQLVQVLRYEPYYDCALTH
FLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRCNIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLQSPLNPNVLLSGIN
VEKCRYMDSKMKPLWIVYNNKLLTGDTLGIIFKNGDDLRQDMLTLQILKLMDLLWKEANL
DLRVVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEQAYLILRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKTDDEALKQFRHKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A4W3JP07|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPAMTDPLDIWAVDSQIPADNSITVDFLLPTGIYIQLDVPREATIDQIKMLLWRQAQTY
PLYTVLGEKDSYMFQCVNQSAVHEELEDESRRLCDVRPFLPVLKLVARNCNRSERLLDSK
IGVLIGKGLHEFDALTDPEVREFRSKMRMFNEEKMLKLQGLSWMDWLKHSFPPELESTAF
NNFEDKLPKENLVVAVQFDSCQENFSFQISPNLNPLDLNELAIRKQLTIHGKENEEFNPR
DFVLRVSGKQEYLFGEQPLIQFRYIRNCVLKGSNPQLTLVDCCTIKEMCDREMSAIGVAL
HRKISNAPLPLPPKSTTSCYIPFKMLLIRGNKINADEAVQVRAGIFHGTELLSKSVVSTE
VSGKNDLVWNEILDFEINLCDLPRMSRLCFAVYGVMDKVKKQKSTKNASKYQTIRKAGKV
HYPIAWVNTMVFDFRAQLKSGDLDLHCWSSFPDEMEDMLNPMGTVQTNPYSENAASLHIQ
FQEYSKSVIYYPAFDKILEKAAEIARSNDTLSMSGRGGKKLHIELKEIMERDPLSQLCEN
EMDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDVAQLQALLQIWIKLCPRDALELLDFN
YPDQYVREYAVKCLKEMSDEELSQYLLQLVQVLKYEPYFDCALSRFLLERAQANRRIGHF
LFWHLRSEMHLPATSLQFGLILESYCRGSFTHIKELSKQMEALSKLKAINNLVKLSYLKV
TRTKVKEVMNTCLKQPVYTEALSDLQSPLNPSVILSKLNVDKCKFMDSKMKPLWILYNNK
MSGGEPVGIIFKNGDDLRQDMLALQILRLMDMLWKEAGLDLRIVPYGCLATGDKSGLIEV
VSASETIANIQLTNSNVAATAAFNKDALLNWLKEKNTGDALDRAIEEFTLSCAGYCVATY
VLGIGDRHSDNIMVRETGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKP
GNAEKFGRFRQCCEEAYLILRKNGNLFITLFALMLTAGLPELSSVKDIQYLKDSLALGKS
DDEALKQFRQKFDEALRESWTTKVNWMAHIVAKDNRS
>A0A4W3H5R1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPGMQYHQDLWSEDENPDVEVEFLLPTGIYLNFYVPRSSTISYIKKLLWQQAQQQPLFH
TLNEPDAYVFTCINHTAEREELEDERRRLCDVRPFLPVLKLVAREGDRAEKLINSQISLL
IGKGLHEFDCMQDYEVAEFRLKMRQFCEDKESERLRMSWQDWMEYSFPRELEPIQEAPDN
NMIRTLSNRNIVINVKFQYNEESFSFQISPQSHPGTLMQMAVKKKATVFRHKTVEHTEDY
TLQVNGTEEYIYGNYPLGQFKHIWNCMYSSSTPHLTMVHSSTINSLKGEQSNSIAQVPKS
RTYSKPPPLPIKKVIIARCFISWIIILVVQAGLFHGSEMLCKTVSSHEVSVCSEPAWDQA
LEFDIHFSDLPRMTRLCFALYGVIDKAKKARSTKKKSKKADCPIAWVNTMVFDYKDQLKT
GDVWLHMWPSIPDEKGELLNPMGTVQGNPNTDSAAALYVRFRNMGSYPIYYPSFDKILEL
GKNGDHSKASPTEQQQLKEIMERKSCTEFFEDEKDLVWKLRWESRDHYSDALAKLLSITK
WNKHEDVAQMIYLLQSWPELPALHALELLDYSYPERYVRSFAINCLKNLSEEELFQYLLQ
LVQVLKYEPYLDSELTKFLLNRALANKKIGHFLFWHLRSEMHVPAVSLRFGLILEAYCRG
NNYHMKSLMKQCESLKKMKALNDFVKSSSQKTTKPKTKEALHLFMRQEAYMEALSNLHSS
LNPSSLLTDLWVDKCKFMDSKMKPLWIVYKNEKYDGDPMGVMFKNGDDLRQDMLTIQMIQ
LMDVLWKRQGLDYRMIPYACLSTGDKTGLIEVVSRSETIANIQLNKSNMAATAAFNKDAL
LNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHF
LGNFKSKFGINRERVPFILTHDFVHVIQQGKTSNSEKFERFRKYCEHAYMILRKHCPLFI
NLFALMRAAGLPELSSSKDIQYLKDSLALGKTEEEALKHFKMKFDEALRESWKTKVNWMA
HNVAKDNRS
>A0A674K7S8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Terrapene carolina triunguis|TrEMBL
MPPGIYCPVEFWSKEENQTIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVRDPEVNDFRAKMRQFCEEKAAKRQQLSWMAWMEYNFPLQLEPLAKGPRT
GPLRVPNKNIFVNVKFESGGESFTFQVSPKEFPVMLMSYAIKKQATVFRHQTVESPEDYT
LQVKGKCEYLYGNYPLYQFQYIRSCLHHGLMPHLTMVHFSSIIAMRDEQTNCTAHTPKMV
SKPPPLPKKKPTHESLWSLNQPFYIELVQGSKVNADERMKLVVQAGLYHGNEMLCKMVSS
AEVNVCSEPVWKQRLDFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQSNPNTESAAALVICFPSVLL
HPVYYPSFEQLLELGRNGDYTRATPEDPEEKQQLREILERRSHTELYEHEKDLVWKMRFE
IRDQYPEALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFTI
NSLKKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSNYHMKVLMKQGEALNKMKALNDFIKVSSQKATKPQAKEMMHV
CMKQETYLEALSNLQCPLNPTVILAEVCVDHCTFMDSKMKPLWIVFNNEEAGGRGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRD
YCEKAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3B4DGS9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pygocentrus nattereri|TrEMBL
MVWLWCALYHASRHDGSVGCVVRSRAGWRRPGNCGFLVAYWNLHSDGCSPREHHPTDQTG
EIDSHIFECVNQAAVHEELEDESRRLCDVRPFLPVLKLITRNCGRAERLLDSKIGVLIGK
GLHELDALQDQEVKDFRIKMQRISEEKMQRVQTMSWGEWLHSCFPPQIEAGPFEDDRNEG
DIKITMHYNQSQDTASLKVSLSCTVAELMEQALRKWLTTHSSEENKGYLGDYVLRISGKL
DFLFGEHTLIHYKYIRSCLLAQEIPHFTMVHCSDVMAMFEHEISTIGAVLTRKSSNPPLP
LPPKRRGLSQMHTCVWEVHSLFKIILVKGIKVNADETAKVQVRAGLFHGTELLCKPAVSN
ESSGRSEYVWNRTLEFEISICDLPRMARLCFAIYAVMDKVKKQKSTKNAQMNKYQTIRKA
GKVHYPIAWVNTMVFDYRGQLKTGDIILHTWSSFPDELEEMLNPIGTIQTNPYTENATAL
HIRFPEYSTHPVIFPPFDKILEKAAEIAGASDSMSMGRGGKKFHIELKEIMERDPLSQLC
ENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPRLHPRDALELLD
FNYPDQYVREYAVSCLQDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLERAQTNRKIG
HFLFWHLRSEIHMPAVSVQFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKLGTI
KAKNKTKEAQLKEAMMKCLRQTGFIETLSDLHSPLNPQVLLGGVNVEKCRYMDSKMKPLW
IVYHNKLLVGDTLGIIFKNGDDLRQDMLTLQILKLMDILWKEANLDLRVVPYGCLATGDR
TGLIEVVSSADTIANIQKNSSNMAAAAAFNKDALLNWLKDKNPGDALEKAIEEFTLSCAG
YCVATYVLGIGDRHSDNIMVCSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHV
IQQGKTGNTEKFGSFRQYCEDAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKVH
SYTSQKN
>A0A674K3M6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Terrapene carolina triunguis|TrEMBL
MPPGIYCPVEFWSKEENQTIQVDFLLPTGIYLNLSVSCNASLGTIKQVPAFTYEPLYHML
NDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIG
KGLHEFDSVRDPEVNDFRAKMRQFCEEKAAKRQQLSWMAWMEYNFPLQLEPLAKGPRTGP
LRSGSLMIPACCCEESFTFQVSPKEFPVMLMSYAIKKQATVFRHQTVESPEDYTLQVKGK
CEYLYGNYPLYQFQVSLFPPPTGELFPKRTGTFLSGRQEKDAPCYCRPCSLCRPTHESLW
SLNQPFYIELVQGSKVNADERMKLVVQAGLYHGNEMLCKMVSSAEVNVCSEPVWKQRLDF
DISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGEC
CLHMWSSFPDEKGELLNPMGTVQSNPNTESAAALVICFPSVLLHPVYYPSFEKGSGNSAL
AGRGHFRFRLSPIRSCEQKQQLREILERRSHTELYEHEKDLVWKMRFEIRDQYPEALAKL
LIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFTINSLKKLTDDELF
QYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPAVALRFGLILE
AYCRGSNYHMKVLMKQGEALNKMKALNDFIKVSSQKATKPQAKEMMHVCMKQETYLEALS
NLQCPLNPTVILAEVCVDHCTFMDSKMKPLWIVFNNEEAGGRGVGIIFKNGDDLRQDMLT
LQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAF
NKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHI
DFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRDYCEKAYMILRCH
GLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTK
VNWLAHNVSKDNRQ
>A0A6I9IFN7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vicugna pacos|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8D2LFJ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Varanus komodoensis|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCLPNGMIVTLECLREATLLGIKHDLFKEARKYPLFH
LLQEESSYIFVGVTQEAEREEFFDESRRLCDLRLFQPILKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDPEVQEFRRNILSVCREAVETRGSAGPQSQALYVYPPNVESSPELPKH
IYNKLDKGRIIVTIWVIVSPNNDKQKYTLKTPHDALPEQVIAEAIRKKTRSMHLSPEQLR
LCVQEYQGKYLLKVCGCDEYLLEKYPLSQYKYMRNCITIGRLPHLMLMSKESLYSQLPAN
VFVLPSYARRSATASHVNGDVPTKSLWSINSLLRIKILCATYVNVNIRDIDKIYVRTGIF
HGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDLPRAARLCVSICSVKGRKGAKEEHCP
LAWGNINLFDYKDTLVAGKMALNLWPVPHGLEDLLNPIGVGGSNPNKETPCLELEFTWYS
HTVKFADATEIEEHANWTMSRELGLNYCMVGLSNRLARDSSLDESELEQLRNICNRDPLS
EITEQEKDFLWRHRHYCVNIPETLPKLLLSVKWNSRDEVAQMYCLLREWPLIRPELSMEL
LDCNFPDPAVREFALKCLVKGLTDDKLSQYLIQLVQVSAPQAGQWGPPRPSRAASVSRGA
PGPRRSTRRPPRPGHHTGGSGRRTGRRGVPSLERGPGHGGQGWGLGPPAAAPSSDGVESR
GLRLSFWGPFGKHTSRVWTRDVPQLRKEEAKGSAGWAGWGRAASSRAE
>A0A8C6UP62|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neogobius melanostomus|TrEMBL
APLSVYGLWDRMVWKNAKSEALFSALGDPDAYVFTCINQTAEREELEEESRRISDVRPFM
CVLRLVAREGDRVEKLTNAQISLLIGKGLHEFEAQKNHEVNEFRTKMRAFCEEKALERQL
LPWRLWMEYSFPCDLEPCCSPHEEGNNKKKNTKIFVNIKFEASEVSGFSLGCYSGILSHE
PQASSLTFQHYLFDKEQLCFDYTLQVNGRWDFIYGDHPLCQFKYMFSCLRNGQAPQLTMV
HHSTISKYQEEQGRMSNQLFQSRSLSRPPPLPLKKVRQQVVSGNTKMIIILSFPVSLQLV
VQAGLFHGSELLCKVVTSSEVTVRSEPLWDQKLEFDISVSDLPRMSRLCFALYAVIEKTK
KPRGTKKKNKRADCPIAWVNTMVFDYKDQLKTGEFLLSAWPSVPDDKSDLLNPMGTVEKN
PNVDSAAGLLIRFPNIRPHPLYYPPLDKKADVEKNGDASAVSKDELLRLKEIMDNKNYTE
FFEDEKELLWKLRYEVRERYPESLSKLLLITKWNKREEVVLVLLRNWPDLPAIQALELLD
YSFPDPSVRSFTIRCLKKLSDPELLQCLIQLVQVLKYESYLDCDLTTFLLERALSNQRIG
HFLFWHLRSEIHVSSVGLRFGLILEAYCRGNIHHIKLLTKQNEALTKMKALSDIVKSGSH
KMTVDDLKLCIRQESYMEALSDLLSPLNPSIILTQICADKCRFMDSKMKPLWMMYRNPCF
QGEMVGIIFKNGDDLRQDMLTLQMIHLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVK
NSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPGDRLEQAIEEFTLSCAGYCVATYVL
GIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNN
SEKFERFREYCEWAYKILCHNGILFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEE
EALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A7L4H5D9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Podargus strigoides|TrEMBL
MELGDYEEPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEVSQTADFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVEEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDNSELDFVLRVCGRDEYITGETPIKGFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNVWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRVTSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEIWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSIHYQQRFVVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQGI
>A0A091DHH0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fukomys damarensis|TrEMBL
MPPGVDCPMEFWTEEENQNVVVDFLLPTGVYLNFPVSLNANLSTIKQVLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDVRPFLPVLRVVAREGDRVKKLINSQISLL
IGKGLHEFDSLGDPEVNDFRAKMRQFCEEAAARRQQLGWEDWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDTPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGRHEYLYGSYPLCQFQYICSCLHNGLTPHLTMLHSSSILAMREEQGNPTSQVQKPR
PKPPPIPTKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
LEVSVCSEPLWKQRLEFDISICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANIMLFDYRDQLKTGERRLYMWPSVPDEKGELLNPAGTVHGNPNTESAAALVICLPEVAP
HPVYYPTLEKILELGRHGEQHGRITEEEQVQLREILERRGSSELYEHEKDLVWKMRHEVQ
EHFPDALSRLLLVTKWHKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKS
LRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPS
VALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCM
RQETYLEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGTAGSVGIIFK
NGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQL
NKSNMAATAAFNKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDNI
MIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGY
CERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKF
NEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K7WEK1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothocercus julius|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSGNLSSMELISIEFILPTSLKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHMFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIVGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PPGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEVVAKTYQLLAKKEVWDQSALDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFVKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITEA
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSVHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>F7EMH6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ornithorhynchus anatinus|TrEMBL
MAPGVDCPMELWSKEENQVLVDFLLPTGVYLNFPVSRNANLSSIKEILWRQAKREPLFHM
LSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPFLRLVAREGDRAKKLINSQISLLI
GKGLHEFDSLRDPEVNDFRSKMRQFCEETAAQRQQLDWEAWMRYNFPLQLEPLAMARTSG
TSFLSKTILVVIKFEGSEESFTLQVSLRDVPLALIAVALKKKATVFRPPALERPEEYTLQ
VNGKYEYLYGNYPLYQFQYVCSCLHEGYTPHLTMVHSSSILAMRDEQSHGSAQGPKLRPK
PPPIPLKKPASVALWSLEQPFWVELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSSSE
VNVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWAN
IMLFDYKDQLKSGECCLYMWSSVPDEKGELLNPTGTVRSNPNTESAAALVICIPEVAPHP
VYYPALERQQQLKEILDRKLSGELYEHEKDLVWKMRHEIQEQFPEALARLLLVTKWNKHE
DVAQMLFLLRSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVL
KYESYLDCELTKFLLDRALTNRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSNHHM
KVLMKQGEALNKMKSLNDYVKVSSQKTPKPQAKELMHTCMRQETFLEALSNLQSPLNPST
LLADVCVEQCTFMDSKMKPLWIVYSNEEVTGSSSVGIIFKNGDDLRQDMLTLQMIQLMDV
LWKQEGLDLRMTPYGCLSTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWL
KSKNPGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNF
KTKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRGYCERAYTILRRHGLLFLHLFA
LMRAAGLPELSCSKDIQYLKDSLALGKTDDEALKHFRVKFNEALRESWKTKVNWLAHNVS
KDNRQ
>A0A4W4HIY1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MPPGVCYGMQDVWEKGGREQVTLEFLLPTGIYLSFPVARNDTIGTIKKMVWKNARSEPLF
SVLSDPDAYVFTCINLTAEREELEDESRRLCDVRPFMPVLRLVAREGDRVEKLINTQISL
LIGKGLHEFDTQKNHEVNEFRAKMRSFCEENAQDRQRLPWHQWMKCNFPCDLEPFSMVVQ
SGKSCSVKKLLVNVKFEASEESFMLQLDPQDFPVVLMQNALRKKATVFRPLKQEKPENYT
LQVNGRWQFIYGNSPLCQFKYIFSCLYGGIKPHLTMVHHSTIIKYQEEQGGLSNQVSKSR
SLSKPPPLPLKKQNTSSLWSIKEPFFIQLVHGTRVNTDEGMKLVVQAGLFHGGELLCKVV
TSSEVSVCSDPVWDQKLVFDINLCDLPRMSRLCFTLYGVLEKTKKQRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSAPDDKGDLLNPMGTVERNPNIDSTAGLLIRFPSF
RPHPLYYPPLEKLNDPEINGEKVVATKEEMVCLLRTWRDLPPLHALELLDYTFPDPHVRS
FTIRCLKKLGDEELFQYLLQLVQVLKYESYLDCDLTTFLLERALSNKKIGHFLFWHLRSE
MHVASVSLRFGLILEAYCRGSIYHIKSLMKQIEALNKMKALNDFVKSGSQKSASRLQITE
DMKLCIKQDTYMEALSDVISPLSPSIVLSEICPDRCKFMDSKMKPLWLMYKNKWDHLDTV
GIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMVPYGCLSTGNKTGLIEVVKNADTI
ANIQRNSSNNAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDR
HSDNIMIRENGQLFHIDFGHFLGNFKAKFGINRERVPFILTYDFVHVIQQGRTNNSEKFE
RFRECCEQAYKILCRNGTLFVNLFALMRAAGLPELSCSKDIQYLKGLLWHRE
>A0A4W4EVI2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MPPAMTDLLDLWVEPGLDGDDQVTVDFLLPTGVYIKMDVPRQSSLQCIKQMLWKQAQGYP
LFTLLGEMDSHIFECVNQAAVHEELEDESRRLCDVRPFLPVLRLIARNCGRAERLLDSKI
GVLIGKGLHELDALQDQEVKDFRSKMQRISEENMQCVHMMSWGEWLQSCFSPQIEAGPVN
GYCDGSEGEVKIIMHYSESQVQTDVCTVAELMEQALRKWLTTHGSEEDEGCLGDYVLRVS
AKLEFLFGDHPLHHYRVRLKVNRGCSCSSWSCVCMQVQVRAGLFHGTELLGKVAVSSESS
GRSEHVWNKALEFDLSICDIPRMSRLCFAIYAVMDKVKKQKSTKSVCLFKALYPIAWVNT
MVFDYRGQMKTGDITLHTWSSFPDELEEMLNPIGTIQTNPYRENATALHIRFPEYSPQPV
VFPPFDKVCTLNYDRMLHDMQHRGKKFYVELKEIMERDPLSQLCENEKDLIWTLRYDCRE
NFPQSLPKLLLSVKWSKHEDMAQVLHALLQIWPKLSPRDALELLDFNYPDQYVREYAVNC
LQDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLRRAQANRKIGHFLFWHLRSEMHMPA
VCVQFALILEAYCRCSVPHIEVLKKQVEALSKLKAVNELIKLGTIKTKKMKEAQLKDAMM
KCLRQTGFIETLSDLHSPLDPQVLLAGVNVERCRYMDSKMKPLWIVYNNKLLVGDTMGII
FKNGDDLRQDMLTLQILRLMDILWKEANLDLRIVPYGCLATGDRTGLIEVVSYSETIANI
QKNSSNMAAAAAFNKDALLNWLKDKNPGDALEKAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFR
QNCEDAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEDALKQFRQ
KFDEALRESWTTKVNWMAHNVAHPS
>A0A6P4V0U9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera pardus|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINICDLPRMARLCFAIYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A5E4C001|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Marmota monax|TrEMBL
MELENYEQPVILREDNLRRRRRMKPRSVAASLSSMELIPIEFVLPTSQRDTKIPETALLH
VAGHGNVEQMKAQVWLRSMETSVAADFYHRLGPDHFILLYQKKGQWYEIYDKYQVVQTLD
CLRYWKMLNKSPGQIHVVQRHAPSEETLAFQQQLTALIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVASRDARLYAMHPWVTSKPLPEYLSRKITNNCIFIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDRPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIFCGKAPALSGKASAETPSSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLQDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLETLQNSNLP
KSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A3Q1DDN4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amphiprion ocellaris|TrEMBL
MDGQQIQVSDEEPEVLREESRRRRRRKKAITSSPCTSMDQISVEFVLPTVARGGNGPDSL
LLEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQQFSPDHCILLYQKKGNVCEIYDKHQVFQ
TLDCIRYWRALKKDVGRIQLVPRPQPSEESQQYQNYLNCLIGYDVTDVSNVHDDELEFTR
RKLLTPRRIELSDRDPKLYSMDPWVTRKPLHEHLRTKINNSHILVVIHISTASQTIKVSI
DDTPTQVLASFFAKTANKRVLLGIPENKCETDFVLRVCGREEYLYGEKPLQNFNWVRQCL
KNGEEIHLVLETPPDPELDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDC
NRKFRVKVLGIDIPSLPKVPEFVVFIEASIFHGQQLLAQERTTSKSFNEEVLWNCWLEFN
IKIKDLPKGARLNLQVICGKQPQTSNSKGGYYQDNTAGTSSLDGKTKSRLLYYVNLLLID
HRSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVL
PKSRDVGRDYGAAGEEAEGGERGQREMPNHLKKQFEAIVATDPLHPLSPEDKELLWHFRH
ECMRDPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQV
RSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLR
SEIAQSMHYQQRYAVLLEAYLRGCGENMLQDFRKQVEMTEALQKVTCEIKAMSDDKYHVT
AQVVFQLRQKLETLQASGLPESFRVPYDPGLRAGVLLIEQCKVMASKKKPLWLQFKRADP
TTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIE
IVKDATTIANIQQSVVGSTGAFKDELLCQWLRDKCVSEEKFQQAVERFLFSCGGYCVATY
VLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGK
KSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRS
EDDAQRHLLDQIEICREKGWMVQVNWFVHLVLGIKQGVEKRST
>A0A3Q7WR04|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus arctos horribilis|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSVLENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C8J2M8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRVKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQLSKS
RSLSKPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVV
TSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIHFPNI
RPHPLYYPHFDKPTSYICNHYTCNHLLKEIVDNKNYTEFFEDEKELLWKLRGVVRERYPE
SLSKLLLITKWNKHEDVAQMVTFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLR
DEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRF
GLILEAYCRGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAY
MEALSYLLSPLNPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDTVGIIFKNGDDLR
QDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSA
ATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETG
QLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYK
ILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDSRL
>A0A8C8J991|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
ICLFLCQQSCLFILFDLYVLNKDTVGSLLQRFCFPLSGFIYRHLDFPLNASSEPLYGALS
DADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLLIGK
GLHEFDSQKNHEVNEFRVKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEPGGI
KTKGTKKIFVNVKFEASDVSQEPQDLPVILMRSALKKKATVFRSVRQEKPEDYTLQVNGR
WEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQLSKSRSLSKPP
PLPVKKVSGQPLGTTLVVQAGLFHGSELLCKVVTSGEVNVCSEPLWDQKLVFDISVSDLP
RMSRLCFALYAVIEKAKKPRSTKKKNKKAVITSLCGFFHQDCPLAWVNTMVFDYKDQLKT
GEFLLSTWPSVPGDLLNPMGTVEKNPNVDSAAGLLIHFPNIRPHPLYYPHFDKVIATKLK
EIVDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKLLLITKWNKHEDVAQMVTFLQKWP
DLPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATF
LLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGNIYHIKSLWKQNEALNKM
KALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLLSPLNPSIMLSEICADRCKFM
DSKMKPLWLMYKNKWVQGDTVGIIFKNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPY
GCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIE
EFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFI
LTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFK
DIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDSRL
>A0A6P6D4A4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Octodon degus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A6P6MA74|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carassius auratus|TrEMBL
MPPGVFGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACNETISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLINTQISLL
IGKGHHEFESQKNHEVNEFRMKMRTFCEERAQVRQMLPWDQWMEYNFPCDLEPCSVVAQS
GKSCSVKKIFVNVKFEGSEETFVLQQDPHDLPVLLKQNALRKKSTVFRSTKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVI
SNEVSVCSDPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNDLGMNGEKASKEEHLKLKEIVDNKNYTEFFEDEKELLWKLREEVRQRY
PESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRK
LSDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVSSVSL
RFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQD
TYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDNVGIIFKNGDDLRQ
DMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAA
TAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQ
LFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRQCCEQAYKI
LCRNGILFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRES
WKTKVNWMMHTFAKDNR
>A0A8C1XTS9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSPELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLARLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTEADIEQLRQLSNRDPL
SEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNRGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A061HZ27|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cricetulus griseus|TrEMBL
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFILPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDHFLLLYQKKGQWYEIYDRYQVVQTLD
CLRYWKMMHKSPGQIHVVQRHAPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKITNNCILIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMNIPESQSERDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
DEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPTLSSKASAEMPGSESKGKAQLLYYVNLLLIDHRFLLRHGDY
VLHMWQISGKVEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGMAMLQDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSSLP
KSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFQCADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETECLDLCLLPYGCISTGDKIGMIQIVKDATTIAQIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVRAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A6J0DLL0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Peromyscus maniculatus bairdii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
SFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A2Y9TH96|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Physeter macrocephalus|TrEMBL
MCYRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATMSYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGRLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKAI
NPSKYQTIRKSGKVDYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYIEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDHSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>D4A5Q1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rattus norvegicus|TrEMBL
MPPGVDCPMEFWTKEESQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLHVSNRPLLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVERPEEYA
LQVNGRHEYLYGSYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
VKPPPIPAKKPSSVSLWSLEQPFCIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDISICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELMNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGRITEEEMLYLLCSWPELPVLSALELLDFSFPDCYVGSFA
IKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMH
VPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKASSQKTTKPQTKEMMH
MCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEKAGGAGSVGI
IFKNGDDLRQDMLTLQMIQLMDFLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIAN
IQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERF
RGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQTLWH
>A0A2Y9LSJ4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Delphinapterus leucas|TrEMBL
MELENHEQHVVLREDNRRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLHALETSVAADFYHRLSPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRLAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDTKLYAMHPWVTSKPLPEYLLKKITNNYIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIRNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKAEDHGSINADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCSFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTMDIKSLSAEKYDVSSQVISQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSRHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A6J2CDX7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zalophus californianus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECFKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVDCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3Q7P466|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinus ursinus|TrEMBL
MWISTRFRQNLFQVMSGMELKHHEQPVVLREDNGRRRRRMKPRSSAASLSSMELIPIEFV
LPTSQRNSKTPETALLHVAGHGNVEQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQKK
GQWYEIYDKHQVVQTLDCLRYWQVLHRSPGQIHVVQRRAPSEETLAFQRQLTALIGYDVT
DVSNVHDNELEFTRRRLVTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFII
IHRSTTSQTIKVSADDTPGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVG
ETPIKNFQWVRHCLKNGEEIHLVLDSPPDPALDEVRREEWPLVDDCTGVTGYHEQLTIHG
KDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKP
FTEEVLWNVWLEFSIKIKDLPRGALLNLQIYCSKAPALSGKASAETPGSESKGKAQLLYY
VNLLLIDHRFLLRHGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNY
CHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESL
KHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAI
AVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEI
AQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQV
ISQLKQKLENLQNSNLPESFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTAL
SNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVK
DATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLG
IGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTS
LYFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEE
AKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>Q3UDT3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|TrEMBL
MPPGVDCPMEFWTKEESQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLRVSNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYA
LQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGRITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMR
QETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C4U5R3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Falco tinnunculus|TrEMBL
CCSEALSQLSSHPAVGLAQVVWKHAQYEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRR
LCDIQPFLPVLRLVAREGDRVKKVINSQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCE
ERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGTGSLHISTKNIFVNIKFHFTFQISPKEFP
ITLMSYAIKKQATVFRHETVEKPEDYTLQVNGKCEYLYGNYPLYQFQVSLVSCFINESVP
IRPALPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVNV
CSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWVNVML
FDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVASHPVYY
PSFDPGYALSCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLI
ITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHDVFQY
LLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAY
CRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHVCMKQETYLEALSHL
QSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQ
MIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNK
DALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDF
GHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGL
LFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVN
WLAHNVSKDNRQ
>A0A671T7D3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPGVYGMQDVWEREGWQQVNMEFLLPTGIYLNFPVTCSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVCQMLPWDQWMEYNFPCDLEPCSVVAQS
GKSCSDKKIFVNVKFEGSEETFVLQQGPQDLPMFLKRNALRKKSTVFRSAKQEKPEDYAL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLEFDISVSDLPRMSRLCIALYGVIEKTKKRPTKKKNKSSDCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGMNGEKTVATKEEHLKLREIVDNKNYTEFFEDEKELLWKLREEVRQ
RYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHARSFTIRCL
RKLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVSSV
SLRFGLILEAFCRGSIFHIKNLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIK
QDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDTLGIIFKNGDDL
RQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNS
AATAAFTNLTPRHSPDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHI
DFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRN
GTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTK
VNWMMHTFAKDNR
>A0A671TB94|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPGVYGMQDVWEREGWQQVNMEFLLPTGIYLNFPVTCSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVCQMLPWDQWMEYNFPCDLEPCSVVAQS
GKSCSDKKIFVNVKFEGSEETFVLQQGPQDLPMFLKRNALRKKSTVFRSAKQEKPEDYAL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRLVVQAGLFHGSELLCKVVTSNEVSVCSEPVWDQKLEFDISVSDLPRMSR
LCIALYGVIEKTKKRPTKKKNKSSDCPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPDDKG
DLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKLNELGMNGEKTVATKEEHLK
LREIVDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVGLLRK
WPELPAIHALELLDYSFPDPHARSFTIRCLRKLRDDELFQYLLQLVQVLKYESYLDCDLT
CFLLERALANKKIGHFLFWHLRSEMHVSSVSLRFGLILEAFCRGSIFHIKNLMKQNEALN
KMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCK
FMDSKMKPLWLMYKNKYDTLGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYG
CLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFTNLTPRHSPDKLDQAIEEFTLSCA
GYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVH
VIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKD
SLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A671SIX2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPSAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYTMPLEAGSLE
SLIDKHEDVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGFRSDY
VLRVSGKLEFLFEDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIGSVIAR
KTSNPPLLLPPKKRLPTKLHTCVWKVHSLFRINLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHYELEEMLNPIGTIQTNPYTENAT
ELHISFPEYSTQPVVFPVFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMERDPLSQ
LCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALEL
LDFNYPDQYVREFAVYCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRK
IGHFLFWHLRSEMFMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFG
TIKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGINVERCKYMDSKMKPLW
IVYNNKLLEGETVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDH
AGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAG
YCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHV
IQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDS
LALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A671K4N2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MEHQASDDEPPVVRREENKRRRRKMKAFTSTSAVLTDQIAVEFVLPTTNKNSKNPDTLHL
DVTGNWTIEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWNEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVVRQQPTEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDPKLYSMDPWITTKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKN
GEEIHLVLERPPDPEQDVVQKEEWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERG
QREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEA
VAITHCLLERSTIWDRSSLDVGLALQLLDCHFSDENVRTMAVRKLETLEDDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALGSMRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRG
CGEAMLQDFRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDNF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFLGISKERVPFVLTPDFLYVMCTTDKKSSPNFLQFQNVCLKAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQ
FNWFLHLVLGIKQGTIRHAFMATVGKIVNVWCLTFWHFPDHGFAYHSQPAQFHFLRVGSE
VVDRFGLAQTEAGGRMIHRPLDVLNLVTQKRDGTLGFDILVTKSRRNQTHSRSILTFKSR
TYKLLKLGRW
>H3CMT6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tetraodon nigroviridis|TrEMBL
AMPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLH
HLLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGF
AIGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESSQELPK
HIYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQL
KMCVQEYQGKYILKVCGCDEYLLEKHPISQYKYIRSCIMLGRMPNLMLMAKDSLYSQLPT
DNFVMPSYSRRISTATSYMNGEVAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTG
IYHGGEQMCDTVNTQRVPCSNPSRWNEWLTYDMYISDIPRAARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLEMEFD
HFSSSVKYPDMNAVEDHANWTISREMGLNYTLSGQSNRAARDHILTESDSEQLRQLGNRD
PLSEITEQEKDFLWRHRYYCMKIPEILPKILLAVKWNSRDEVAKMYCLLKEWPSIRPEQA
MELLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKAL
TNQRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDI
LKQEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRP
LWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQSQGLDLRMLPYGC
LSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDMAVDLFT
RSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQ
DFLIVISKGSQECVKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDD
IAYIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A2K6P7P0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinopithecus roxellana|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRRQLSWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
TEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKCKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVHSNPNTDSAAALLICLPEVAP
HPVYYPTLEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7K7HVH0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhegmatorhina hoffmannsi|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEIILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
TQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKEKCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A663E764|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aquila chrysaetos chrysaetos|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHIWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHVKFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRDDLDRAIEE
FTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6P6M3L5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carassius auratus|TrEMBL
MEHQASDEEPPVVRREENKRRRRKMKAFTSNSAVSTDQIAVEFVLPTTNKNSRNQDTLQI
DVTGNWTVEQVKVQIWHRAVTTKLCPDFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVVRTQPSEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDPKLYSMDPWMTTKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFAKISKKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKN
GEEIHLVLEHPPDPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTCKEYECKNKSRLLYYVNLLLVDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKDNSMAVAILLDKYCYPVALPKSKDSPDSEKEGERG
QREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEA
VTITHHLIERCTVWDRSSLDVGLALQLLDCHFSDENVRTLAVRKLETLEDDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALRSQRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRG
CGEAMLQDFRKQVEITEALQKVTREIKQMSAEKYDVSAQVVLQLRQKLEVLQTSGLPDSF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITESGNLFHI
DFGHILGNYKSFMGISKERVPFVLTPDFLYVMSTTGKKNSPHFLQFQNVCLKAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEEEAKQHFLDQIEICRDKGWTVQ
FNWFLHLVLGIKQGVEKRSA
>A0A7K5VQY7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Platysteira castanea|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPREFPITLMSYAVKKQATVFRHETVQKPEEYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
CKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWRQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAAEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGMGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L4EAC3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hirundo rustica|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKNFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERIFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTASKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKANLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A803XQG1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Meleagris gallopavo|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQVSLLSLKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNA
DERMKLVVQAGLFHGNEMLCKMVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNP
MGTVQCNPNTESAAALVICFPNVASHPVYYPSFEQVGNMDVFLRAWLPRLSHISILLPTS
IFHYTPVFLHLSGLSKAFGLRLSPLYALCCDSHEQKLQLKEILERRSHTELYEHEKDLVW
KMRYDIRDQYPQALAKLLTITKWNKHEDVAQDSFPPHKGSALPATWPELPVLNALELLDF
SFPDRYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGH
FLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPK
ATKPQAKEMMHVCMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNN
EETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIE
VVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVAT
YVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGK
TNNSEKFERFRGYCEKAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGK
TDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C7MF13|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPAMTNLMDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQAYFTNILNIEVL
DVNEDNVLSLQDTASLKVWPSTIPSELMEQALRKWLTTHGPEEEGRQAEQYVLRVSDKLE
FLCGDHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISAIGAVVNRKSSNPPLPL
PPKRRGNIINHVSTHFKIVLIKGSKVNAEETAKIQVRAGLFHGTELLCKPAVSSESSGRS
EHVWNRTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKSTKNAHINKYQTIRKSGKVHYP
VAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPIGTIQTNPYTENTTALHIHLPD
YNPHTILFPPFDKILEKAAEIAGSSDCLPMGRGGKKFHIELKEIMERDPLSQLCENEKDL
IWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQ
YVREYSTRSQTRSHITIPSSLTVVIDEELSQYLLQLVQVLRYEPYYDCALTRFLLNRAQC
NRNIGHFLFWHLRSEMHMPAVAVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELI
KLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMD
SKMKPLWIVYNNKLLGGDTLGIIFKNGDGTRGLDLTLTWCISMLLMMIHWNKMCLCRIVP
YGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKAI
EEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPF
ILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTSV
KDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A8C7J9Q4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPAMTDDLDLWAAHSQLCGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFCPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQQVQLMTWSEWLQACFSPQLEPGGG
ATPVTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISA
IGAVVNRKSSNPPLPLPPKRRGPSQVNTCVWEVSTPFKIVLIKGSKVNAEETAKVQVRAG
LFHGTELLCKPAVSSESSGRSEHVWNLTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKS
TKNAHINKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPI
GTIQTNPYTENCTALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCSTMGRGGKKFLI
ELKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQ
IWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCAL
TRFLLNRAQCNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEAL
SKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSG
INVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEA
NLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNS
GDALEKVIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFG
IKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTA
GLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A8C7H6T1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRVKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQLSKS
RSLSKPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVV
TSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIHFPNI
RPHPLYYPHFDKVHLILHTHLQYVHSTPSLLTLYCAAQHMKLKEIVDNKNYTEFFEDEKE
LLWKLRGVVRERYPESLSKLLLITKWNKHEDVAQMVTFLQKWPDLPALHALELLDYSFPD
PMVRSFTIRCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFW
HLRSEMHVSSVSLRFGLILEAYCRGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQ
QMTDDMKLCIKQEAYKDALSYLLSPLNPSIKLSEICADRCKFMDSKMKPLWLMYKNKWVQ
GDAVGIIFKNGDDLRQDMLTLQMIQLMEILWKKEGLDLRDKLDQAIEEFTLSCAGYCVAT
YVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGR
TNNSEKFERFRECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGK
SEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDSRL
>A0A4U1EJQ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodon monoceros|TrEMBL
MPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQ
EAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPE
VQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIW
VIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVC
GCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRRISTAT
PYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQR
VPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDT
LVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEH
ANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPLSEITEQEKDFLWSHR
HYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFA
VRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEM
HNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFL
VEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQ
NNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSH
TIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGD
RHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTR
EFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEA
LEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C4D233|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPRPSSGELWGIHLMPPKILVDCLLPNGMILTLECLREATLITIKHDLFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLMKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESSSELPKH
IYQKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMATVEDHANWIIAREMGYNYCQSGQSNRLVRDLVMTEGEIEQLRQVGNRDPL
SEITEQEKDFLWRHRHYCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRFEECRIMSSAKRPLW
LNWENPDIMSESLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERLGLCFTM
>A0A7K5FJH4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Probosciger aterrimus|TrEMBL
MELEDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAANCTVEQMKAQIWMRALEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQNPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKVKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDPKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISVVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDICVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>H2M7Z5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETCYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDFEVQDFRRNILNVCKDAVELRDANGPHSRALYVYPPNVESSQDLPKH
IYSKLDKGWVTGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSP
EQLKMCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYSQ
LPTDSFVMPSYCRRISTATSYMNGEAAPKSLWTISGGLRIRILCATYVNVNIRDIDKIYV
RTGIYHGGEQMCDNVNTQRVPCSNPRWNEWLNYDMYILDIPRAARLCLSICSVKGRKGAK
EEHCPLAWGNINLFDYNHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELE
FEHFSSPVKYPDMNAVEEHANWTISRELGFNYNTSGQSNRVARDHALTDSDSEQLKQLKW
PSIRPEQAMELLDCNYPDPMVRHFAVRCLDKFLADDKLSQYLIQLVQVLKYEQYLDNPLA
RFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAME
KLINLTDILKQEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLEDCR
IMSSAKRPLWLNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLD
LRMLPYGCLSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNRGEMY
DMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRE
RVPFVLTQDFLIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGM
PELQSFDDIAYIRKTLALEKGEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A2I0MHE6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Columba livia|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTADFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEDDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C9D2J8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera leo|TrEMBL
MELDNYEQPVVLREDNRRRRRRMKPRSTTASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVATDFYRRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQIHVVQRHAPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCSKAPVLAGKTSAETPSSESKGKTQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTDQVQVIEML
QKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLPKSFRVPYDPGLKAGALVIEKCK
VMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDL
CLLPYGCISTGDKIGMIEIVKEATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQ
AAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKER
VPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQL
TSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A8C5EM40|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
LPTYLFINWFISVHQRLSFQLLWKQAQMFPLFPALGEMESHMFECVNQAAVHEELEDETR
RLCDVRPFLPVLKLVTRNCGRAERLLDSKIGVLIGKGLHELDAINDQEVKDFRSKMFRIS
EERMQQVQMMTCTEWLQACFSPQLEPAASAIISDGVIYIIVLVMFQDSASLKVSWSCTSA
ELMELALRKWLSTHGPEEDACRGQYVLRVSHCLEFLCGDHPLIQYKYIRSCLQAKESPHL
TLVHTRTIQAMFDKEISAIGSVVSRKTSNPPLPLPPKRRVPTTCVWDVSSPFKIVLVKGS
KVNAEESAKVQVRAGLFHGTELLCKPSVSSESNFRSDHTWKDSTLEFDISVCDLPRMTRL
CFAIYAVMDKVKKQKSTKNSIKLLDCIRYHYPIAWVNTMVFDYKGQLKTGDIILHCWSSF
PDELEEMLNPIGTIQTNPYTENATALHIHFPEYLSHPIIFPPFDKVRHPVVQQCTSPQSL
KEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQVLLQIW
PKLSPRDALELLDFNYPDQYVREYAVGCLQKVVLVLRYEPYYDCALTHFLIERAHGNRVI
GHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGT
IKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSIQLSGINVERCRYMDSKMK
PLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRVVPYGCLAT
GDRAGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALERAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDF
IHVIQQGKTGYTEKFCNFRQNCEDAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7L2UJR6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balaeniceps rex|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPTAKGLGT
GLLHTPTRNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHFSTIIAMRDEQANCIASPPKMS
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRTGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKSSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C5EPP2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
MPPAMTDLLDIWAPHSPLAGHTLAQITVDFLLPTGIYIQMSVPREATIQHIKLLLWKQAQ
MFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRISEERMQQVQMMTCTEWLQACFSPQLEPA
ASAIISDGVSDRPTDLKVTIHFDQSQDSASLKVSWSCTSAELMELALRKWLSTHGPEEDA
CRGQYVLRVSHCLEFLCGDHPLIQYKYIRSCLQAKESPHLTLVHTRTIQAMFDKEISAIG
SVVSRKTSNPPLPLPPKRRVPTVSHTCVWDVSSPFKIVLVKGSKVNAEESAKVQVRAGLF
HGTELLCKPSVSSESNFRSDHTWKDSTLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKST
KNAHINKYQTIRRAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYLSHPIIFPPFDKVRHPVVQQCTSPQSVGRGGKKFHIELK
EIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQVLLQIWP
KLSPRDALELLDFNYPDQYVREYAVGCLLYSSIDEELLQYLLQLVQVLRYEPYYDCALTH
FLIERAHGNRVIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSIQLSGIN
VERCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRVVPYGCLATGDRAGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGYTEKFCNFRQNCEDAYLILRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKVFLAQTDMLKKRTYYIKVSFFAVMQRSAFTSFLQ
>A0A091QFR5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptosomus discolor|TrEMBL
SRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGL
GTGLLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPED
YTLQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPK
MTAKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
VSHPVYYPSFEQVGDMDTFWGRGAQKFPSSAGAGAYGKLQLKEILERRSHTELYEHEKDL
VWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDR
YVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWH
LRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQ
TKEMMHVCMKQETYLEALSHLQSPLNPNVILAEVCVDQCTFMDSKMKPLWIVFNNEETGG
GGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHS
DTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGI
GDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGFNRERVPFILTYDFVHVIQQGKTNNNE
KFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEA
LKHFRLKFNEALRESWKTKVNWLAHNVSKDNR
>A0A7L3TRN1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Uria aalge|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQATDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPLLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A673ICK8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYSMPLEAGSLE
NLIDKHEASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGFRSDYVLHVSGKLEFLFEDH
PLNQCKVRYVARNGFESSNYIFQGFVHSLFRINLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKPRSTKNTHLN
KYQTIPWVNTMVFDYRGQLKTGDIILHCWTSFPDELEEMLNPIGTIQTNPYTENATELHI
NFPEYSTQPVVFPAFDKPMIAVCRCCAEFCTPARLCTPSLKSLLDCLIPTPPLILTPPPP
LLLNLPILGGGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLL
LSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVYCLQDMSDDELLQ
YLLQLVQVLRYEPYYDCALSRFLLERSQSSRKIGHFLFWHLRSEMFMPAVSVHFALILEA
YCRGCIPHIEVLKKQVEALSKLKAVNELIKFGTIKTKTKQAHLKEAMMTYLCVCTYMDSK
MKPLWIVYNNKLLEGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCL
ATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTH
DFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQ
YLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A4W2DNZ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos indicus x Bos taurus|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASMSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDSLWGKKKKPHAHCDLCLIPLMLLNIPSVSADVT
NVPKARKASSSFQDLLSSDSITTETHKHQMENWNLCALALICCSGSTIMNCKICLNSAHR
VNLSSTIMIACFLTEAGNNQRDSPGPLYSSP
>A0A673IVW5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMRDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGLCHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWDQWMEYNFTCDLEPCSVVA
QSGKSCSDKKIFVNVKFEGSEETFVLQQGPQDLPMFLKRNALRKKSTVFRSAKQEKPEDY
TLQINGRWEFIYGKYPLCQFKVSLKITPSSRLHSYIFFKLHIKASHFQTPGCMSFIYLQN
TSSLWSINEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSNEVSVCSEPVWD
QKLVFDISVSDLPRMSRLCIALYGVIEKTKKRPTKKKNKSSDCPLAWVNTMVFDYKDQLK
TGEFSLSTWPSVPDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKTLILTNG
TVFFQHLKLREIVDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVA
QMVGLLQKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLRDDELFQYLLQLVQVLKYE
SYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVSSVSLRFGLILEAFCRGSIFHIKNL
MKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLC
ELCADKCKFMDSKMKPLWLMYKNKYDTLGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGL
DLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGD
KLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSKFGIN
RERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMKAAGL
PELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A673III0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSAELPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKITHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDEYLLEKHPLSQYKYIRSCITLGRLPHLMLVSKDSLYSQLPSS
GFMAPSYSRRTPQPSPCPGGGDPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDEQQIEEHANWKYIKSFNQEKLAGGSRLVCDSSISQADAEQLRTLCSRDPL
YELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVHNLDIFLRWKNAVLQMLETW
LSKERLLSNSTPRFLTDDEELTEQPSSLRQCSRLLYAEVLLMSPSSPITETADWLMKLIL
HSDWLLQTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLN
WENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIG
DCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIRDKNKGEAYDRAIDLFTRSCA
GYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLI
VISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYL
RKTLALEKNQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A7K6TRD6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aegotheles bennettii|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAARRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPIRTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKVV
AKPPPLPKKKPNYGSLWSLEQPFYVELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDYELFHYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
SAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLCIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIQETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A4W6FMP8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPEGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNIINVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKPLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFISPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFER
>A0A4W6C836|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TLPLFSALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRISEERMQRVQMMTCAEWLQACFSPQLEPT
AGTAITDGVNDRLADLKVTIHFDQSQDSASLKVPSSCTSTELMELALKKWLTTHGPEEEA
WRGQYVLRLSQRLEFLCGDHPLIQYKYIRTCMQAKESPHLTLVHTSAVKAMFDKEISTIG
AVVSRKSSNPPLPLPPKRRVPTHTTCVWDVSNSFKIVLVNASKVNAEENAKVQVRAGLFH
GTELLCKPAVSTESSGRSDHTWKESTLEFDISICDLPRMTRLCFAIYAVMDKVKKQKSTK
NPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDINLHCWSSFPDELEEMLNPIGT
IQTNPYTENATALYINFPEYSSHPVVFPPFDKILEKAAEIARASDCAPMGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVCCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTH
FLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALNK
LKSVNELIKLGTTKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGIN
VERCRYMDSKMKPLWIVYNNKLMGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A4W6FZK7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lates calcarifer|TrEMBL
MDGQQTQVSDEEPKYLREETRRRRRKKAITSSSSASMDQISVEFILPTVARGGNSPDSLQ
LDVAGNWTVEQVKAQVWLKAVTSNLCPEFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVSNSHILVVIHIGTASQTIKVSID
DTPAQVLASFFTKTANKRVLLGIPDNMCEADYVLRVCGREEYLYGDKPLQNFNWIRQCLK
NGEEIHLVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDGKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVVCGKQPQTPNSKGSSYQDNTAGGGSHDGKTKSRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLP
KSRDVGRDVAAVGEDVEGGERGQREMPNHLKKQFAAIVSTDPLHPLSPEDKELLWHFRHE
CMRDPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVR
SMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSMHYQQRYAVLLEAYLRGCGEAMLQDYRKQVEMTEALQKVTREMKAMSADKYDVTA
QVVFQLRQKLETLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPT
TLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKK
SSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSE
DEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A7L0QGL7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Setophaga kirtlandii|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNQHTKAPEMMLLE
IAGNCTVEQMKAQVWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K8MC54|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ptilorrhoa leucosticta|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAVKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKAA
SKPPPLPKKKPNFGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L0Q584|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Setophaga kirtlandii|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPTKNIFVNIRFQSGGESFMFQISPWEFPITLMSYAVKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAASK
PPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFDIR
DQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A484BZZ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Perca flavescens|TrEMBL
MDGQQIPVSDQEPKALREDTRRRRRKKAIMSSSCTSMDQISVEFVLPTSERGGNSPEMLQ
LEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCICYWRALKKDVGRIQLVPRPQPSDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIQLADRDAKLYSMDPWVTRKPLPEHLLSKISNGNILVVIHIGTASQTIKVSID
NTPAQVLVSFLAKTANKRSLLGIPDNMCEADFVLRVCGREEYLYGDKPLQDFNWIRQCLK
NGEEIHLVLEAPPDTDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPEFIVFVEASIFHGQQLLAQERTSSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVVCGKQSQTPNSKGSSAYQDNTAGTGSHDGKIKSRLLYYVNLLLID
HRSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASAMAVAILLDKYCYPVVL
PKSRDVGRDAAAAAGGGEDAEGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWH
FRHECMRDPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSD
AQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKTALRSKRIGHFLFW
FLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTREVKAMSADKC
DITAQVVFQLRQKLETLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKR
ADPTTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIG
MIETVKDATTIANIQQSVVGSTGAFKDEILCQWLRDKCVSEDKFQQAVERFLYSCGGYCV
ATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGT
SGKKSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTV
GRSEDEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A669DMQ4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRCKMFRISEERMQQIQMMTFSEWVQACYSPQLEPA
AVTAITAGVNDAPADLKVIIHFDQSQDSASLKVSLSCTPNELMEQALKKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKDTPHLTLVHTSAVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRRAPTVSPNIMHDSVNNIISIFMSVSANRLMFSRTETEGVQVR
AGLFHGTELLCKPAVSNESSGRSEHTWKDNTLEFEISVCDLPRMTRLCFAIYAVMDKVKK
QKSTKNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEML
NPIGTIQTNPYTENATALHIHFPEYSSHPIVFPPFDKVTQYWKKAAEMVSADCVSIGRGV
KKFYMELKEIMERDPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQL
QALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPY
YDCALTHFLLERAQRNRQIGHFLFWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKK
QVEALSKLKSVNELIKLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPS
VLLSDINVEKCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDL
LWKEANLDLRIVPYGCLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWL
KERNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNF
KSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFA
LMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVA
KDNRS
>A0A8C8CBX6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPAMTNLMDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQACFSPQLEPGGG
ATPVTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISA
IGAVVNRKSSNPPLPLPPKRRGPSVSQTIPVCIQVRAGLFHGTELLCKPAVSSESSGRSE
HVWNRTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKSTKNAHINKYQTIRKSGKVHYPV
AWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPIGTIQTNPYTENTTALHIHLPDY
NPHTILFPPFDKILEKAAEIAGSSDCLPMGRGGKKFHIELKEIMERDPLSQLCENEKDLI
WTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQY
VREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLNRAQCNRNIGHFLFWHL
RSEMHMPAVAVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSKT
KEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLVEKCRYMDSKMKPLWIVYNNKLLGG
DTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSSA
DTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKAIEEFTLSCAGYCVATYVLGI
GDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTE
KFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDDEA
LKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A671TZT3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MPPGKYGMQEEWEKEGDQGIVMDFLLPTGIFLKFPVSRHDTIKSIKKMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEVKAQERQALPWQQWMEYSFPCDLEPCSSPPVC
GSVKSKNTKKIFINVKFEACDESFMLQQDPQDLPVALMRSALKKKATVFRSVRQEPEDYT
LQVNGSWEFIYGNHPMCQFKVNWEGKMKCPLVLQQNTSSLWSINEPFYIHLLQGSRVNAD
EGMKLVVQAGLFHGSELLCKVVTSSEVTVSSEPLWDQKLEFDINVADLPRMSRLCFALYA
VIEKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPM
GTVEKNPNVDSAAGLLIRFSNIRPHPLYYPPLDKVLILKGFFSGYKLIFEYALRNGDAAI
ATKEEVISYFLILTRSRSGLLLVFHVVVVALSQYMKLKEIMDNKNYTEFFEDEKELLWKL
RTEVRDRYPESLSKLLLITKWNKREDVSFDSPQMVSLLRNWPDLPAIHALELLDYSFPDP
AVRSFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLATFLLERALSNRRIGHFLFWH
LRSEIHVASVSLRFGLILEAYCRGNIQHIKLLTKQNEALGKMKALSDFVKSGSQKMTVDD
LKLCIRQESYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNTCAQGDMVG
IIFKNGDDLRQDMLTLQMIRLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIA
NIQRNSSNSAATAAFNKDALLTWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRH
NDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFER
FREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNF
KVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A671U1V1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MPPGKYGMQEEWEKEGDQGIVMDFLLPTGIFLKFPVSRHDTIKSIKKMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEVKAQERQALPWQQWMEYSFPCDLEPCSSPPVC
GSVKSKNTKKIFINVKFEACDESFMLQQDPQDLPVALMRSALKKKATVFRSVRQEPEDYT
LQVNGSWEFIYGNHPMCQFKYIFSCLRNGQNPHLTMVHHSTISKYQEEQGRMCSQVFKSR
SLSRPPPLPLKKNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SSEVTVSSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFSNIR
PHPLYYPPLDKVLILKGFFSGYKLIFEYMVSLLRNWPDLPAIHALELLDYSFPDPAVRSF
TIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLATFLLERALSNRRIGHFLFWHLRSEI
HVASVSLRFGLILEAYCRGNIQHIKLLTKQNEALGKMKALSDFVKSGSQKMTVDDLKLCI
RQESYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNTCAQGDMVGIIFKN
GDDLRQDMLTLQMIRLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRN
SSNSAATAAFNKDALLTWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIM
IRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERYNIIV
FVFFLLLYLKACKECHFLTFETIKVFERKALNVCLHIL
>A0A671ULL3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSVELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMTIIEDHANWNISRELGFNYCHTGLTNRLARDNPLTDTDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCLNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A671WHU7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MDGKQIQVSDEEPRVVREETRRRRRKKAITSSSCSSMDQITVEFVLPTTARGGNSPDTVL
LDVAGNWTVEQVKAQVWLKAVTLNLCHDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTRKLLPDHLLSKVSNNHILVVIHIGTVSQTIKVSID
DPPAQVLASFFAKTANKRVLLGIPDDMCEEDFVLRVCGREEYLYGEKPLHNFNWIRQCLK
NGEEIHLVLESPPDPELDQVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVNTPTPNSKTGSRGLFLSVRFSGKTKSRLLYYVNLLLIDHRSLLRQ
GEFILHMWKMPEKSEESSSSINADKLTSATNPDKASAMAIAILLDKYCYPVVLPKSRDVG
RDVGAGGEEAEGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPR
AYPKLLGSVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRK
LETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSM
HYQQRYAVLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTREVKAMSADKYDITAQVVFQL
RQKLENLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDP
IGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATT
IANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVEKFLYSCGGYCVATYVLGIGDR
HNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQ
KFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRH
LLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>F7FDA0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodelphis domestica|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISHIKQMLW
KQAHSYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKVVTRNCDPGE
KLDSKIGVLIGKGLHEFDALEDPEVMEFRSKMRQFSEEKIQSLIGLSWMDWLKHTYPPEQ
EPSIPENLEDKLYGGNLVVAVHFENCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDE
VDPYDYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPKLTLVECCNIKKMCEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISVTWGAVDDLDILGVHVRAGLFHGTELLCKPVVSSEI
SGRNDHVWSEPLEFDINICDLPRMARLCFAVYAVDKVKTKKSTKAINPSKYQTIRKAGKV
HYPVAWVNTMVFDFKGQLKSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIK
FPENKKQPYYYPPFDKIIEKAAEIASSDSGNVSSRGGKKFHVVLKEIMERDPLSQLCENE
MDLIWTLRQDCRENFPQSLPKLLLSVKWNKLEDVAQVSSSSIWPKLPPREALELLDFNYP
DQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLDRALANRRIGQFLF
WHLRSEVHIPAFSVQFGVILEAYCRGSVGYMKVLSKQVEALNKLKTLNSLIKLNAMKLNK
AKGREAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLRIVYNNKVF
GGDPVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVS
TSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVL
GIGDRHSDNIMVRKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGN
TEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSDE
EALKQFKQKFDEALRESWTTKVNWMAHTMRKDYRS
>A0A3Q2UNI3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gallus gallus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLDTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPIKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQVNSIANPPKMA
VKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNVAS
HPVYYPSFEQLLELGRNGEQPRSAPEDPEEKLQLKEILERRNHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLTITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHV
CMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERIPW
LWVKRMKRH
>A0A1A8LU31|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius pienaari|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREAALNTIKHELFKEVRKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDSSGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRMPNLMLMAKDSLYTQLPTD
SFVMPSYSRRISTATSYMNGEAASKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSVCSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVASKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNFPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSPECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>O42391|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gallus gallus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3P8YMV3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MAKQVSDEDLHSVVHREENRRRRRKMKAFTSTFSVIMDQISIEFVLPTSTKSSRSPDTLL
LEVAANWTVEQVKAQVWLRAVASNLCPEFYQKFSPDHCILLYQKKGNWCEIYDKHQVFQT
LDCIRYWKALKKDVGKIHLTCRPQPSEDSVRYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLFSPRRIELSDRDPKLYSMDPWITSKPLPEYLLAKVTNNHILLVIHKSTASQTIKVSID
DTPVQVLQTFFAKIANKRALLGIPDDMCEADYVLRVCGREEYIYGNHPVRDFHWIRQCLK
NGEEIHLVLESAPNPEQDQVQREDWAQVDDCTGVAGTHEQLTIEEKDHERVFTISLWDCS
RKFRVKVLGIDIPTLPRNPELIVFVEASIFHGQQLLAQERTTSKAFTEEVLWNTWLEFNI
RIRDLPKGSRLSLQVSCGKAQTQPTKGNSSYHEIGAGGGGGHDKTKSRLLYYVNLLLVDH
RSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMALAILLDKYCYPVALPK
SRESKEPGGDGRSAEGGERGLREMPNHLRKQFEAIIETDPLHHLSPEDKELLWHFRQECM
RHPSAYPKLLSSVRWGRQEAVLATHRLLERSTVWDRSPLDVGLAMQLLDCHYSDANVRSM
AVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEI
ATSMHYQQRYAVLLEAYLRGCGDDMLQDFRHQVEMTEALQKVTREIKTMSAEKYDVSAQV
VFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTR
SSDTIGIIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVK
DATTIANIQQSVVGSTGAFKDEILNQWLQDKCVNEEKFQQAVERFVFSCGGYCVATYVLG
VGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSS
PHFLKFQDVCVRAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGHPEEE
AQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVEKRSA
>A0A3B3V7H2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia latipinna|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGDILYAIFFSLCTPSTSPEESCYIFVGVTQEA
EREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFAIGMPVCEFEMMKDPEVQ
DFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPHLPQHIYSKLDKGRLIVTIWVI
MSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLRLCVQEYQGQYILKGATA
LRHLRQRQHPGH
>A0A8B7X2E8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcebus murinus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPLFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRTFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSIFENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
ASPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRKSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKHYPVAWVNTMVFDFKGQLRSGDLILHSWSSFPDELEEMLNPMGTVQT
NPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEI
LDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKL
PPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQFLFWHLRSEVHIPAISIQFGVILEAYCRGSVGHMKVLSKQVEALNKLKT
LNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDS
KMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGC
LATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEF
TLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>G3WV63|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sarcophilus harrisii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVHAPHSRALYVYPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASTKSLWGVNSALRIRILCATYVNVNIRDIDKIYVRTGI
CHGGEPLCDNVNTQRVPCSNPRWNEWLMYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMSVIEEHANWTVSRELGFNYSHAGLSNRIARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFE
>A0A7N4NVI9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sarcophilus harrisii|TrEMBL
MDLEDHDPVILREDNRGRRRKMKPQSAGMNLSSMEFIPIEFVLPTTHPLTKVAETVILEA
AGNCSVEQVKAQVWMQAVETSMTMEFYHQSSPEQFLLLYQKKEQWYEIYDKYQLIETLDC
VKYWKAFHKNMGQIHVVQRQPPTEETWAFQKQLNDLIDYDVTDMSNVHDDELEFTRRRLV
TPRIMEVASRDPKLYAMHPWITSKPLPTYLLKKIVNNCILIVIHRSTTSQTIKVSADDTP
GTILQSFFTKMAKKKSLMDIPESQNELDFVLRVCGRDEYIVGETPIKNFQWIRHCLKNGE
EIHLVLDTPPDPGQDEVRKEDWPLVDDCTGVTGYHEQLTINGKNHERVFTLSLWDCDRRF
RVKIRGIDIPVLPRNTELTVFVEANIQHGQQVLCQRRTTSKPFTEEVLWNVWLEFDIKIK
DLPKGALLNLQIYCGKAPSQSSKAAGSHEISSFEAKGKTQLLYYVNLLLIDHRYLLRHGE
YVLHMWKISGKGENQGSMNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPE
GDRVRGEMPNQLRKQLEEIIATDPLNPLTAKDKELLWHFRYESLKHPKAYPKLFSSVKWG
QQEIVAKTYQLLARREAWDQSDLDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHY
LLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEA
YLRGCGMAMLEDFTKQVQVIRLLQKVTIEIKSLSAEKYDVTSQVISQLKQKLENLQNSNL
PKSFRVPYDPGLRAGILMIEKCKVMASKKKPLWLEFKCADPTAQSNETIGIIFKHGDDLR
QDMLILQILRIMGSIWEAESLDLCLQPYGCISTGDKIGMIEIVKDAITIAKIQQSTVGNT
GAFKDEVLNHWLKEKCPIEEKFQAAVEKFVYSCAGYCVATFVLGIGDRHNDNIMITETGN
LFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDICAKAYLA
LRKHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKG
WTVQFNWFLHLVLGIKQGEKHSA
>A0A3Q0D4V2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mesocricetus auratus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVDDFRTKMRQFCEEVAAHRQQLGWEDWLQYSFPLQLEPSARSWRA
GILRVANRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEDYA
LRVNGRHEYLYGNYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPAKKPSSVSLWSLEQPFCIELMEGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAP
HPVYFPALEKILELGRHGERGHITEEELQLREILERRGSGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQLSQMLYLLCSWPELPVLSALELLDFSFPDSYVGSFAIK
SLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVP
SVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMC
MRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGRAGSVGIMF
KNGDDLRQDTLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCERAYTILRRHGQLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2R9BD77|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan paniscus|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVRPPRPSPCFPGPQPSSVSLWSLEQPFRIELIQGSKVNAD
ERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYA
VIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPT
GTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKLPGGMLLASCEWRPELLWMRLHAEDS
APSRMIGVAMPGLGVLPGLVQAPGDAECSCLLQILELGRHSECVHVTEEEQLQLREILER
RGSGELYEHEKDLVWKLRHEIQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVL
SALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRA
LANRKIGHFLFWHLRYSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A812DTK2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sepia pharaonis|TrEMBL
MPDVSAKVKPNGEISLDFLMPNGILIPMSVDFYCSTFEKIKQDLWLESVNFPLYNLLRHC
DTYTFLFVNSRGQKEEVLSESQSLSEIKPSVTFLKLIEKEPNSERCYSFDRRITSLIGAP
IVDLTDYQSLEVSDFKLRIKYETEKIIQERDLMGWEERMRYLYPLRLINDQLLNKISLKL
KHGSGCIDVCREQKSFKEIVDMNSTPKSLIIHLLKKFSNLWKLPDTDPSNFMLKVKGYEE
YLYGDYCLLHFKYIYECLQKDIIPSIFLVTRSEIVIPAPVVPPHRRLAPPLLSPSPSRVG
SQKSSIYSWNISSNVNIFVKSVSQVQTTESRVKLVTGLYHGPDILCAAAKTEETLLYDQS
CTWNSNLNFDHLIKDLPEMTRVCFMLMAVGGVKKKQKDTTPLAWVNISLFDFRSQLRQGE
YELYMWSVTEDESIPEEESCFPIGTVTPNPAGKNATTLTIGFPSYNAKEKIIYPPKEVVL
ECAARNMEPEGTLGSPMWRSNKIVMDQLSTILQQGPVNQMFEQDKELVWRLRHEVQHHYP
ESLALLLSSVKWSNYIDVAKLQALLISWPRLNCELSLALLDFTYADKAVREFAVNCLEQL
PDDEVTQYLLQLVQVLKFEMYLYCPLVKFLLTRALRNRRFGHKLFWLLKSDMHDRQMNLR
FSLILEVYCKSSQDHTTDLIKQNEALLKIDAANMLIKNSTLALNDRKNKENLSADLRKVL
CQNAYSMALSNLHSPLNPLWNLKKLLVQKCKFLDSKMRPLWLVWENEELKENECHFSIIY
KNGDDLRQDMLILQVIQIVDFIWQEEGLDLRLNPYGCICTGRNTGMIEAVDAQTIANIQR
KFDKASNRCVYEWLKEMNPKKENLDKAVEEFTLSCAGYSVITYVLGICDRHNDNIMIKKN
GQLFHIDFGHILGNTKKKFGVVRDRVPFVLTNHFVTVIKNGEKPNDNFQRFQEICEKAYM
TLRRRGTILITLFRLMIQSGLPELSSEKHVEYLQKSLALGVSDEEAIQQFNAKFKESLNK
CWTTSLNWWFHMRVVDNT
>A0A3B4UV21|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola dumerili|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTETDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDLAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8D0CAT5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salvator merianae|TrEMBL
MPPGIYCPVEFWSKEANRNIQVDFLLPTGIYLNLLVPCSATLSTIKKAVWHHAQYEPLFH
MLSDPDSYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSSGDPEVNDFRAKIHQFCAERAAQRQQLSWRAWMEYSFPVQLEPLAGSPER
KNSLRIPNKNIFVNVKFESGGESFTFHISPKELPMTLMSYAVKKQATVFRHQRINSPEDY
TLQVNGKCEYLYGNYPLYQFQYIHDCLHHGLLPHLTMVHSSSIMALWEEQANGIAHSPKS
VARPPPIPKKKPTSASLWSFDQPYYIDLVQGSKVNADERMKLVVQAGLYHGNEMLCKMVS
SSEVSVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIA
WVNVMLFDYKDQLKTGECSLPMWSSFPDEKGELLNPMGTVQTNPNTESAAALVIHFPSLS
AYPVYYPSLEQILEQGRNGPCPRSKQQLREILERRSHAELYEHEKDLLWKMRYQIRDHYP
GALAKLLVVTKWNKHEDVAQMVHLLQSWRELPVLNALELLDFNFPDRCVSSFTVNSLKKL
TDVELLQYLLQLVQVLKYESYLDCDLTKFLLDRALSNRKIGHFLFWHLRSEMHVPSVAIK
FGLILEAYCRGSPYHMKALMKQSEALSKMKALNDIVKLSSQKISKLQTKEYMHACMRQET
YMEALSNIQSPLNPHIILSKVSVELCTFMDSKMKPLWIVFSNKNMGGSNMGLIFKNGDDL
RQDMLTLQMIHLMDILWKKEGLDLSDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVVQQGKTNNSEKFERFRDYC
ERAYMILRSHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEARKHFQLKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C6XW51|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Naja naja|TrEMBL
MPGMPPGMYCPPEFWSKESNYTIHVDFLLPTGIYLPLPVSCHASLAAIKKVVWHQAQYEP
FFQMLSAPDSYVFTCINQAAELQELEDEQRRLCDVQPFLPVLRLVAREGDRAKKLLNSQI
SLLIGKGLHEFDSLANPEVDNFRLQMQDYCEQRAAQRQQLSWKDWMEYSFPVQLEPTLSG
LGKRPSLPVPGKTIFVNVRFQSGGESFTFQISLKEFPITLMSYAVKKQATIFRHQRVSPV
DEYTLQVNGKHEYIYGEYPLYQFQLTCVSLWSLDQPYYIELLHCSNVNADEGMKLVVQAG
LYHGHEMLCKMMTSTEANVCSEPAWDQTLKFDIHVCDLPRMARLCLALYSVVEKAKKARS
TKKKSKKADCLLAWVNVMLFDYQDQLKAGECVLPMWSAFPDEKGELLNPTGTIQTNPNAE
SAATLFIRFPGISLYPIYYPSMRQILEKGQNGHCAYGTGEDPEEKQQLKEILERRSCIEL
YEHEKDLVWKMRYQIRDQHPGALAKLLMVTKWNKHEDVAQMIFLLQSWPELPVLNALELL
DFNFPDPHVSRFTVNSLKKLTDAELFQYLLQLVQVLKYQSYLDCELTKFLLGRALSNRKV
GHFLFWHLRSEMHFPSLALRFGLILEAYCRGNADHIKALMKQSEALNKLKALNDLIKVSA
QKNTKPQTKEFMHTCMRQETYLEALSQLQSPLDPRIFLARVSVELCTVMDSKMKPLWIMF
NNGEAGGHSTGLIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKMGL
IEVVMNSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCV
ATYVLGIGDRHSDNIMVRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQ
GKTSNSEKFERFRDCCETAYMILRGHGLLFLHLFSLMKAAGLPELSCSKDIQYLKDSLAL
GKTDEEARKQFHLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A4W5JH82|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MEQQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVTMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTLFQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELSDRDPKLYSMDPWITSKHLPEYLLFCQKIANFCCLFPEDVCEADYVLRV
CGREEYIYGNHPVRDFHWVRQCLKNGEEIHLVLESAPNPDQDLVQREDWAQVDDCTGVAG
THEQLTIDEKDHERVFTISLWDCHRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLL
AQERTSSKAFTEEVLWNTWLEFNIRIRDLPKGARLSLQVSCGKAQTQISKGTSSYQDNGG
SPVGGGSGSHDGNKTKSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADK
LTSATNPDKASSMAIAILLDKYCYPVALPKSREGKEAGGEGREAEGGEREQREMPNHLRK
QFEAIVETDPLHPLSQEDKELLWHFREECMRHPRAYPKLLGSVRWGRQEAVLTTHRLLER
SSVWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLETLGDNDVLRYLLQLVQAVKFEPYH
DSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEGMLQDFK
CQVEMTEALQKVTREIKAMSAEKYDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRA
GALVVKQCKVMASKKRPLWLQFKRADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMES
IWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRD
KCVSEEKFQQAVERFVFSCGGYCVATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYK
SFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSM
MLMTGMPQLTSKEDIEYIREALTVGRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLG
IKQGVEKRSA
>A0A4W5R8V8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHEVFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKCPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGESSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMTTVEGHANWTISRELGFNYCQSGQSNRVARDHALTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNIRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCMS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDLAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A4W5LWT4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDTQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLPEP
GGNKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKLVVQAGLFHGSELLCKVVTSCEVNVCSEPLWDKKLVFDISVSDLPRM
SRLCFALYAVIEKAKKPRSTKKKNKKADCPLAWVNTMVFDYKDQLKTGEFLLSTWPSVPD
DKGDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPHFDKVHLLLHTLDNKNYTEFF
EDEKELLWKLRGVVRERYPESLSKLLLITKWNKHEDVAQMVAFLQKWPDLPALHALELLD
YSFPDPMVRSFTIRCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIG
HFLFWHLRSEMHVSSVSLRFGLILEAYCRGNIYHIKNLWKQNEALNKMKALNDFVKSGWQ
KTSRQQMTDDMKLCIKQEAYMEALSYLLSPLNPSIMLSEICADRCKFMDSKMKPLWLMYK
NKWVQGDAVGIIFKNGDDLRQDMLTLQMIQLMEILWKKEGLDLRDKLDQAIEEFTLSCAG
YCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHV
IQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDS
LALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDSRL
>A0A3Q0R4A5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amphilophus citrinellus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLNFPVSRNDTIKNIKKMVWKNARSEALFC
ALGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVGREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRTFCEEKAQDRQSLPWQKWMEYSFPCNLEPCSSLPQS
AKSKNIKKIFINVKFEASDESFMLQQDPQDLPVALMKSALKKKATVFRLMRQESEDYTLQ
VNGTWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTIVKYQEEQGRMCSQVYKSRSL
SRPPPLPLKKLVVQAGLFHGSELLCKVVTSSEVAVSSEPLWNQKLEFDINVADLPRMSRL
CFALYAVIEKTKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKS
DLLNPMGTVEKNPNVDSAAGLQIRFPNIRPHPLYYPPLDKKNGDVSFATKEEYFKLKEIM
DNKNYTEIFEDEKELLWKLRTEVRDHYPESLSKLLLITKWNKREDVVQMVSLLRNWPDLP
AIQALELLDYSFPDPAVRSFTIRCLRKLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLE
RALSNRSIGHFLFWHLRSETHVASVGLRFGLILEAYCRGNIHHIKLLTKQTEALGKMKAL
SDFVKSGSQKMTVEDLKLCIRQESYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPL
WLMYRNPTAEGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRNKLDRAIEEFT
LSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTY
DFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQ
YLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A7L1BJA4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Illadopsis cleaveri|TrEMBL
DSIMPPAVTDSLDIWAVDSQTGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQA
HSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNT
SKYQTIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDLAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C7U7F3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MEQQVSDEEEPQPVVLREEIRRRRRKMKAFTSTFSVAVDQIAVEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCVRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELSDRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVYTISLWDC
HRKFRVKILGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNAWLEFN
IRIRDLPKGARLSLQVFCGKAQTQISKGTSSYQDNGGSPGGGGSSSHDGSKTKNRLLYYV
NLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYC
YPVALPKSREGKAAGGEGREAEGGERGQREMPNHLRKQFEVIVETDPLHPLSQEDKELLW
HFREECMRHPRAYPKLLGSVLWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYS
DAHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLF
WFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEK
YDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVVSGIIPIHLLFSSTSLLAC
LHPFPHHHFLHPPLIVFLLLPSLLRLTLNMGPSLQIEQCKVMASKKRPLWLQFKRADPTT
LSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIV
KDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVL
GVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKS
SPHFQRFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEE
EAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>I3MK14|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ictidomys tridecemlineatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C2YZE1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSKALYVYPPNVESSAELPRH
YYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPEMTIIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A0P7WYP5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLISIKQQLFAEALTQEAER
EEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFAIGMPICEFELVKDPEVQDF
RRNILSVCREAMEEREGGGAHSQALYVYPPNVESSPDLPQHIFCKLDKGRLIVTIWVIVS
PSNAKQKYTLKIAHDCLPEQLIAEAIRKKTRSMHLSAQQLRLCVQEYQGQYILKVCGCDE
YLLEKYPLSQYKLPASGFVAPSYSRRTPQPSPCPGGGDPSPPRSLWAFNTLLRVRLLCAT
YVNVNIRDIDKWLSYDIYLTELPRSARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYKD
TLVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFSWFNQTVIFPDEQQIEE
HANWVISRELGYNYCPGLSSRLACDSTVSQVDVEQLRSLCSRDPLYELSEQEKDFLWRHR
HYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLRDWPLMQPESALELLDCNFPDPMVREFA
LRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFFWHLKSEM
HNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMEKLVNLTDTLKQEKKDETQKMQMKFL
VEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFT
NNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVKNSY
TIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTRSCAGYCVATFILGIGD
RHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQECTKTK
EFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKSQQEA
LEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A7K4YKL4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bucorvus abyssinicus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGA
GSLHTPAKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSAIIAMRDEQSSCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQPFYVELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSIAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILDRRSHTELYEHEKDLVWKMRYD
IRDLYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDLVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEEMGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKVIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K4YSG3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bucorvus abyssinicus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMILLE
IAGNCTVEQMKAQIWMHAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSAEVQEFQRKLNDLIGYDVTDVSNVHDDELEFTRRRL
VTSRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKIQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCIIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITEA
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGESEEGAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8B9QCE0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Apteryx owenii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWSINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKSNRIARDNELRE
SDKEQLRAICTRDPLSEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYC
LVKDWPPIKPEQAMELLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYL
DNQLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQ
VEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLR
LEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQ
NQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKN
KGEMYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKF
GYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMM
LGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQH
ALN
>A0A7J7UDP8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myotis myotis|TrEMBL
MCFNFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
TQIHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
ESSILENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMNPIKINELAIQKRLTIHWKEDE
VSPYDYVLQISGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGT
ELLCKTIVSSEISGKNDHVWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTIN
ASKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQT
NPYTENATALHIRFPENKKQPYYYPPFDKSRGGKKFLAVLKEILDRDPLSQLCENEMDLI
WTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQY
VREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHL
RSEVHIPAISIQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNRAKG
KEAMHTCLKQNAYREALSDLQSPLNPCIILSELYVEKCKYMDSKMKPLWLVYNNKVFGED
PVVVMFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEIVSTSE
TIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIG
DRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEK
FGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEAL
KQFKQKFDEALRESWTTKVNWMAHTVRKDCRS
>A0A8C3BCH4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cairina moschata domestica|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPYCTSSNLSSMELIAIEFILPTSNKHTKIPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYQAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTSLQSHDSPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C3B4S0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cairina moschata domestica|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
NFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEDIDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDVCSPFKITLLKGNKLNTEENAKVHVRAGIFHGTELLC
KTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGEFVLHSWSSFPDELEEMLNPMGTVQTNPYI
ENATALHIKFQEYSKHPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFFVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSIQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C5QUC1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptobrachium leishanense|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMMVVLECLREATLINIKHELFKEARKYPLHH
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRKNILNVCKDAVELRDANGPISRALYVYPPNVESSPELPKH
IESKLDKGQIIVVIWVIVSPNNEKQKYSLKINHDCVPEHVIAEAIRKKTRSMLLSTEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKDSLYSQIPVD
TFTMPSYSRRISTATPYMNGESSAKSLWAINSTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGAEPLCDNVNTQRVPCSNPRWNEWLLYDMFIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDCF
SSPVKFPDITAIEEHANKVLERELGYNYSHVGPANRIARDNEVRESDKEQLKAISNRDPL
SEITEQEKEFLWSHRHYCLNTPDILPKLLLAVKWNCRDDVAQMYCLLKDWLALRPEQAME
LLDFNYPDRMVRSFAVTCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHSKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMKRPDFMDALQGFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSEMLFHNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRYDAAIDLF
TRSCAGYCVATFILGIGDRHNSNIMVKDNGQLFHIDFGHFLDHKKKKFGYKRERVPFVLT
QDFLIVISKGIQECTKTRDFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFD
DIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8B9TVU9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKAPTC
AGDSAYTGLEVLHFQPCESFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYTLQV
NGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANTPKMSAKP
PPLPKKKVKGPRGLTVFSYFFSPQLVVQAGLFHGNEMLCKMVSSSEVNVCSEPVWKQRLD
FDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVSKDCPIAWVNVMLFDYKDQLK
TGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPNVASHPVYYPSFDPLYA
LFCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHE
DVAQMISLLQTWPELPVLNALELLDFSFPDRYVVFYFAFLSTEITNCSKYLLQLVQVLKY
ESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHIKV
LMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCMKQETYLEALSHLQSPLNPSIIL
AEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIFKNGDDLRQDMLTLQMIQLMDVLWK
QEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSK
NPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTK
FGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMK
AAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDN
RQ
>A0A670XZS6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pseudonaja textilis|TrEMBL
MPPAMADILDIWAVDSHIAGDSSVSVDCLLPTGIYISLDVPRDATICHIKQLLWKQAHSY
PLFHLLLEIDSYMFSCVNQTAVREELEDETRRLCDIRPFLPVLQLITRSCDPGEKLDSKI
GVLIGKGLHEFDALQDPEIKEFRIKMRQISEEKMQSLVGLSLMNWLKRTYPPVLEPAVQD
NFQDKLYGGNIVVAIHYENCQDVFSFQVSPNINPIKLNELAIRKWLTIHGKEDEEVNPYD
YVLQVNGKLEYVFGDHPLIQFQYIHCCVINRALPHLTLIECSTIKTMYEQEMIAIEVAIN
RKSNNLPLPLPPKKKRLTQSVWEIVQPFKILLVNGSKLNTEETAKVHIRSGLFHGNELLC
KPIVSSEIAGRNDHVWNEPLEFDINVCDLPRMARLCFVVYAVMDKMKNKKSAKALNPSKY
QTMRKAGKVHYPVAWVNTMVFDFKGQLKTGDLLLHSWSSFPDELEEMLNPMGTVQTNPYS
ENATTLQIRFQEYSKCPIYYPPFDKILEKAAEIARNSDCSGMAGRGGKKFFIELKEIMER
DPLSQLCENEMDLIWTLRFDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPR
EALELLDFNYPDQYVREYAVGCLRQMSDEELAQYLLQLVQVLKYEAFLDTALSRFLLEKA
LANRRIGQMLFWHLRSEMHIPAVSLQFGVILEAYCRGSITHMKVLSKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDTMHTCLKQSAYKEALSHLQSPLNPSVLLSELCIEKCKYMDSKMK
PLWIVYSNKAFGADLVGIIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRLLPYGCLAT
GDYSGLIEVVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNTGEDLDRAIEAFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQCCEEAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKNDDEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C3PW58|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysolophus pictus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A673AF97|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNRDEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSVELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFAMPSYARRISTATPYMNGETATKSLWTINGALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWNISSELGFNYCHTGLSNRLARDNPLTASDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHYCVNMPDILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVMCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A2Y9E117|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Trichechus manatus latirostris|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKISHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFNYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C7AGQ4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neovison vison|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSVLENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDQPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPC
VILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDL
LWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWL
KEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQVSCSLDLLRASVM
LLLIYSTISCAIQAGSLVILGVIFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSV
KDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A672QVI8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPAKTDQLDLWAESGLNGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLGTGSLE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHSPEEDIGTRSDY
VLRVSGRFEFLFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKTMFEKEISTIGSVLAR
KTSNPPLPLPPKKRPPTQLHTCVWKVHSLFRINLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKPAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSP
RDALELLDFNYPDQYVREFAVICLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLER
AQSSRKIGHFLFWYLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVS
ELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLQSPLNPNILLAGVHVERCKYMDS
KMKPLWIVYNNKLLGGDTVSIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGC
LATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
HDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A672QVX9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPAKTDQLDLWAESGLNGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLGTGSLE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHSPEEDIGTRSDY
VLRVSGRFEFLFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKTMFEKEISTIGSVLAR
KTSNPPLPLPPKKRPPTVSTLSVFPALQLIKGVLSFVHLAATNSNAKIQVRAGLFHGTEL
LCKPAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSP
RDALELLDFNYPDQYVREFAVICLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLER
AQSSRKIGHFLFWYLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVS
ELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLQSPLNPNILLAGVHVERCKYMDS
KMKPLWIVYNNKLLGGDTVSIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGC
LATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
HDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A672QVX4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPAKTDQLDLWAESGLNGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLGTGSLE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHSPEEDIGTRSDY
VLRVSGRFEFLFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKTMFEKEISTIGSVLAR
KTSNPPLPLPPKKRPPTVSTLSVFPALQLIKGIQVRAGLFHGTELLCKPAVSSESSSRSE
HVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHYPI
AWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEY
STQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMERDPLSQLCENEKDLI
WTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQY
VREFAVICLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWYL
RSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVSELIKLGTIKTKTKQA
HLKEAMMTCLRQTGFIETLSDLQSPLNPNILLAGVHVERCKYMDSKMKPLWIVYNNKLLG
GDTVSIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSS
ADTIANIQKTSNYDADALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHI
DFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKN
GNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTK
VNWMAHIVAHPS
>A0A7K7VH02|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eudromia elegans|TrEMBL
MPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWQHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRIKMRQFCEDRAAKRQQLNWAAWMEYNFPLQLEPLAKGFGT
GPLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNHPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIANPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYVELVQGSKVNADERMKLVVQAGLYHGSEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSIAS
HPVYYPSFEQLLELGRNGEQPRTALEDAEEKLQLKEILERRSYTELYEHEKDLVWKMRYD
VRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDGELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVEQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALAKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A672GY27|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salarias fasciatus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQLDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRIKMFRLSEERMQRVQMMTCTEWLQACFSPQLEPP
AATAVTDGVNDRAADLKVIIHFDQSQDSASLKVPSCYTPAELMEQALRKWVTTHGPEEEA
WGGQHVLRVSHCLEFLCGDHPLIQYKYIRSCLQAKEPPHLTLVHTNTVKAMFDKEMTAIG
AVVSRRSSNPPLPLPPKRRVPTQVQTCVWDVSSPFKIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESSGQRASSEHTWRDNTLEFDISVCDLPRMTRLCFAIYAVMDKVKKQ
KSTKNSHINKYQTIRKAGKVHYPIAWVNTMVFDFKGQLKTGDITLHCWSSFPDELEEMLN
PIGTIQTNPYTENATALHIHFPEYSSHPIIFPPFDKILEKAAEIVGASDCVSGARGGKKF
YIELKEIMERDPLSQLCENEKDLIWTLRHDCWENFPQSLPKLLLSVKWSKHEDMAQLQAL
LQIWPKLSPRDALELLDFNYPDQYVREYAVRCLRDMSDEELSQYLLQLVQVLRYEPYYDC
ALTHFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVE
ALSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPNVQL
SGINVERCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWK
EANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKER
NSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSK
FGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLVLRKNGNLFITLFALML
TAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDN
RS
>A0A3Q3M741|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MTPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFAEARKYPLHH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRTILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
ISSKLDKGRLIVSIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLH
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIMGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGPPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAADVEQLRSVCSKDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLSDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIRDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQTFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPSDH
>A0A6I9K282|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysochloris asiatica|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKISHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETATKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFNYSHAGLSNRLARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A673T4M5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Suricata suricatta|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLLERPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMREEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSAPDEKGELLNPAGTVRSNPNTESAAALVICLPEVSP
YPVYYPALDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPDLPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKSPLDPSTLLAEVCVEQCTFM
DSKMKPLWLMYSNEEAGGDGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTP
YGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAI
EEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPF
ILTYDFVHVIQQGKTSNSEKFERFRGYCERAYTILRRHGPLFLHLFALMRAAGLPELSCS
KDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2P0XI22|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
IVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLC
DLRLFQPFLKVIEPVGNREEKILNREI
>A0A7K5IEP6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Toxostoma redivivum|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNILLIDHRFLLRS
GDYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRLSSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQEAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6Q8PGN9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKLFFHLLGNSMLR
VGV
>M3ZEF9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xiphophorus maculatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRNASGPHSRALYVYPPSVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLTRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEASSKSLWSINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLPYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMNAVEDHANWIISRELGFNFNLSVNHSGTQQSSRVARDHALTESDSEQMRQL
SNRDPLSEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDDVAQMYCLLKEWPSIR
PEQAMELLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDSPLARFLL
KKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLIN
LTDILKQEKKDETQKVQMKFLVDQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRIMSS
AKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRML
PYGCLSLGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGETYDMAV
DLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPF
VLTQDFLIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQ
SFDDIAYIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>M4A2D1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xiphophorus maculatus|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFIEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIMSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLENFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCENVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVSLFDYMDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
RFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSATDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCLNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTISRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDRVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNHGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLMLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A6P8P4L5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MPPGVYFPADFWAKEQNKNILIDFLLPTGIYITFSVPRNASLGNIKQSLWHHAQYEPFYH
MLSEPQAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVQKLINSHISLL
IGKGLHDFDSVGDLEVRDFRSKMRQFCEEKAAERQQLGWEAWMEYSFPLQLEPSARLLKM
GIFHINSKNIIVNIKFESSEESFTLQISAKEFPLALVRSALKKKAIVFRQQNKEEPEDYT
LKVNGCSDYIYGQYPLCQFKYISGCLYHNLTPHLTLVPTKSIKELRDEQENLSLQVSKLR
SKPPPPPLPVKKLSPVSLWNFEQAFCVKILQGSNVNADECLKLVVHAGLFHGNEMLCKAV
RTAEVSESSEPIWNQMMEFDIGICDLPRMSRLSFILYAVEKTKKARSTKKKSKKADCPIA
WVNTMVFDWKDMLKTGECCLYMWSSAPDDKGELLNAMGTVQSNPNTESAVALRICFPSIS
QHPVYYPPFEKILELGKAGEQQCSTVDEQQQQLKELLERRGSVELYEHEKDMLWKLRHEI
REQYSEALARLLLITKWNRHEDVAQMLYLLQSWPELPVLFALELLDYNFPDRCVRAFTVN
CLKKLSDEELCRYLLQLVQVLKYESYLDCELTTFLLERALANRKIGHYFFWHLRSEIHVP
AVALRFGLLLEAYCRGSHYHMKVLVKQVEALTKMKALNDIVKISSQKATKPQTKEVMHVC
LKQENYLEALLNLQSPLNPSVILGNVCVDLCTFMDSKMKPLWIMYNNEMNQNHVGIIFKN
GDDLRQDMLTLQMIHLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEIVGNSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGVALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKPNNNEKFERFRNYC
EKAYMVLRLHGPLFLHLFALMKAAGLPELSCSKDIQYLKVKQCSG
>U3IZT1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos platyrhynchos|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A093QSG3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phalacrocorax carbo|TrEMBL
SRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGL
GTGPLHIPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPED
YTLQVNGKYEYLYGNYPLYQFQYIRSCLHQGLTPHLTMVHSSTIIAMRDEQTNCITSPPK
MAAKPPPLPKKKVKGDGDPAGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEM
LCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKK
ADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVI
CFPSVASHPVYYPSFEQGLSGLSKSSGLRLSPVYVFSCDSHEQKLQLKEILERRSHTELY
EHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLD
FSFPDRYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIG
HFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQ
KATKPQTKEMMHMCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFN
NEERGGSGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLI
EVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGLSCAGYCVATYVLGIGDRHS
DNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERF
RGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFR
LKFNEALRESWKTKVNWLAHNVSKDNR
>A0A7L1DGS0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Serilophus lunatus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGP
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLQKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3M0KB89|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hirundo rustica rustica|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKNFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERIFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTASKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKANLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A091FSN3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cuculus canorus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCMSSNLSSMELISIEFILPTSNKHTKVPEIMVLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQPPSEVVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGVSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISVVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKDVWDQSILDVGLTMQLLDCNFSDENVRAMAVQKLESLDDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVTELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVVEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A850U0Y3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Grus americana|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMV
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSIAL
HPVYYPSFEQLLELGRNGEQPRTAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A093PQT6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Manacus vitellinus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYIIGETPVKDFHWIRQCLKNG
EEIHLVLDDPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDTKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDICVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C4IA09|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MPPGKYGMQEEWEKEGDQGILMDFLLPTGIFLKFPVSRNDTIKSIKKMVWRNARSEALFS
GLGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPMS
GSMKSKSTKKIFINVKFEACDESFMLQQDPQDFPVALMRSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGKHPLCQFKYIFSCLRNGQNPHLTMVDHTTISKYQEEQGRMCSQVYKSR
SLSRPPPLPLKKNTSSLWSINEPFYINLVQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SPEVAVSSEPLWDQNLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFHNIR
PHPLYYPPLDKVHIPKRQKHILKAIFVSQSFFEDEKELLWKLRTEVRNHYPESLSKLLLI
TKWNKREDVVQMVSLLRKWPDLPAIHALELLDYSFPDPAVRSFTIRCLRKLSDDELLQYL
IQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLSERLQPFGKHSPHQALNQTGN
LTHLYTLTSSSEMCVFNEALGKMKALSDFVKSGSQKMTVDDLKLCIRQESYLEALSDLLS
PLNPSIVLSEICADKCRFMDSKMKPLWLLYKNPQAQGDMVGIIFKNGDDLRQDMLTLQMI
QLMENLWKKEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHI
DFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRN
GTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTK
VNWMMHSLAKDNRP
>A0A7K5Q3E9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Erythrocercus mccallii|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQHEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVLNSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLRT
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETLQKPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
WEVAVCSEPVWRQRLDFDISICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K5P6R2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Erythrocercus mccallii|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHNKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLLKKISNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWVRQCIKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPVALPKHRIPSD
AQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A667XTJ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MDQQQVQVSDEEPVVLREESRRRRRKKAITPSSCASMDQITVEFVLPSAARGGSGPDTLL
LEVAANWTVEQVKAQVWLRAVASNLCPDFYQRFSPDHCILLYQKKGSVCEIYDKHQVFQT
LDCIRYWRALKKEVGRIQLVPRPQPTDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDAKLYSTDPWLTDRPLTEHLLSKVSNGHILLVIHVGSNSQTIKVSID
DTPAQVLASFFTKTANKKALLGIPDSVCEADFVLRVCGREEYLYGDKPVQNFHWIRQCLK
NGEEIHLVLETPPDPALDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKNPELTVFVEASIFHGQQLLAQERTTSKPLSEEVLWNCWLEFNI
RIRDLPKGARLNLQVTAQKTQRELFSTKSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPE
KSEESSSSVNADKLTSATNPDKASSMAVSVLLDRYCFPVVLPKSREAGRDAAAPDEAEGG
ERGQREMPNHLRKQFEAIVATDPLHPLSPEDKELLWHFRHECMRHPRAYPKLLSSVRWGK
QEDVLITHRLLERSTAWDSSRLDVGLAMQLLDCHYSDAQVRSMAVRKLETLGDDDVLRYL
LQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIVQSMHYQQRYAVLLEAY
LRGCGEAMLQDFRKQVEVTEALQRVTREIKAMSADKYDVSAQVVFQLRQKLETLQSSGLP
DSFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSRDAIGIIFKDGDDLRQ
DMLILQILLIMESIWETENLDLSLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTG
AFKDEILHQWLRDRCVSEDKKLCCVCVCVCVCVCVCVCVCVCVCAGNLFHIDFGHILGNY
KSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFHKFQDVCVKAYLALRHHTNLLIILFS
MMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQINWFVHLVL
GIKQGVEKRSA
>A0A674C053|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
CCQLPTSLDKSLSDADAYVFTCINSTAEREELEDETRRLCDVRPFMSVLRLVAREGDRVE
KLTNTQISLLIGKGLHEFDSQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSFSCD
LEPCVSLAEPGGIKTKGTKKIFVNVKFEASDVSQEPQDLPMILMRSALKKKATVFRSVRQ
EKPEDYTLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTIVKYQEEQGCLG
SQVSKSRSLSKPPPLPVKKVRGQPLGTTLVVQAGLFHGSELLCKVVTSGEVNVCSEPLWD
QKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKAVITSFYGFSHQDCPLAWV
NTMVFDYKDQLKTGEFLLSTWPSVPGDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLY
YPHFDKVHLILHTRFNSRHCYSHQGGGKGLSILKEIVDNKNYTEFFEDEKELLWKLRGVV
RERYPESLSKLLLITKWNKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTIR
CLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLKSEMHVS
SVSLRFGLILEAYCRGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLC
IKQEAYMEALSYLLSPLNPSIKLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIFK
NGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQR
NNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNI
MIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREC
CEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKF
NEALRESWKTKVNWMMHSLAKDSRL
>A0A8C0GUJ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelonoidis abingdonii|TrEMBL
MCSIMPPAMTDILDIWAVDSQIGADGLISVDFLLPTGTYINLDVPRDATICHIKQLLWKQ
AHSYPLFHLLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLKLVTRNCDPGEKL
DSKIGVLIGKGLHEFDALQDPEVKEFRSKMRRISEEKLLSLVGLSWVDWLKHSYPPEQEP
SIPENFQDKLYGGNLVVAIHFDKCQDVFSFQVSPNINPVKLNELAIRKRLTIHGKEDEVD
PSDYVLQISGRLEYIFGDHPLIQFQYIHKCVMNRILPHLTLVECCSIKKMCEQEMIAIEG
AINRKSSNLPLPLPPKKTRTSVWDISNPFKIMLLKGNKLNTEETAKVHVRAGLFHGTELL
CKPIVSAEISGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKTINPSK
YQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDLLLHSWTSFPDELEEMLNPMGTVRTNPY
TENATALHIKFQEYSNLPIYYPPFDKQASQSTSKIMERDPLTQLCENEMDLIWTLRYDCR
ENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWSKLPPREALELLDFNYPDQYVREYAVGC
LKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLVERALANRRIGQMLFWHLRSEVHIPS
VSIQFGVILEAYCRGSIAHMKVLSKQVEALSKLKTLNSIIKLNAMKQSKAKGKDAMHTCL
KQNAYREALSDLQSPLNPSVILSELYVEKCKYMDSKMKPLWIVYNNKMFGGDLLGIIFKN
GDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGCLATGDHSGLIEAVSAAETIADIQLN
SSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCC
EDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFD
EALRESWTTKVNWMAHTVRKDYRS
>G5C2D6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Heterocephalus glaber|TrEMBL
MELENSEPPVILREDNLRRRRRMKPRSAASSLSSTELVPIEFVLPTSQRHSKTPETVLLH
VAGHGNVEQMKAQVWFRALETSAAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLQYWKVLHQSPGQIHLVQRHAPSEETLAFQRQLTALIGYDVTDVSNVHDDELESARRRL
VTPRMAEVASRDARLYAMHPWVTSKPLPEYLSKKITNNCIFIVIHRSTTSQTIKVSADDT
PASILQSFFAKMARKKSLMDIPESQSEQDFVLRVCGRDEYLVGDTPIKNFQWLRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRN
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSAKPFTEEIYGGKAPGQSGKS
PAETPGSESRGKAQLLYYVNLLLIDHRFLLRHGEYVLHMWQIPGKGEDQGSFNADKLTSA
TNPDKENSMSISILLDNYCHPIALPKHQPTPDPEGDRVRAEMPNQLRKQLEEIIATDPLN
PLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGEQETVAKTYQLLARREIWDQSALDVG
LTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRG
LRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLQDLAQQVHVIEMLQRV
TIDIKSLSAEKYDVSAQVISQLKQKLENLQNSNLPKSFRVPYDPGLKAGTLVIEKCKVMA
SKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLL
PYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAV
ERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKERVPF
VLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMXXXXXXXXX
XXXXXXXXXXXXXXXXXXXGMPQLTSKEDIEYIRDALTVGKSEEDSKKYFLDQIEVCRDK
GWTVQFNWFLHLVLGIKQGEKHSA
>G5AQ99|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Heterocephalus glaber|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIAVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHSYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEEKIQSLVGLSWIDWLKQTYPPEH
DPSILENLEDKLYGGKLIVAVHFENSQDVFSFHVSPNVNPIKINELAIQKRLTIHGKEDE
ASPGDYVLQVIGRVEYVFGDHPLIQFQYVRNCVVNRALPHFVLVECYKIKKMYEQEMIAI
EAAINRNSSNFPLPLPPKKTRIISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNETLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYHYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAISVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCIILSELYIEKCKYMD
SKMKPLWLVYTNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSDEEALKQCKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K4ZMM8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Centropus unirufus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQNEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLGWAAWMEYSFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHQGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKRPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTDSAAALVICFPSVTS
HPVYYPSFEQLLELGRNGEQPRAVPEDPEEKLQLKEILDRRSYTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELLQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKSLNDFVKSSSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGRAGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A852DK64|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Passerina amoena|TrEMBL
MPPGIYCPTEFWSKGENQSIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSL
QIPTKNIFVNIRFQSGGESFMFQISPWEFPITLMSYAIKKQATVLRPETVQQPEDYTLQV
NGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQINCITSPPKAASKP
PPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSEV
SVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWANV
MLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHPV
YYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFDIRD
QYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSL
KKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPAV
SLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCMK
QETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKNG
DDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNK
SNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMV
RETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCE
RAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A8C6K4T5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Melopsittacus undulatus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GPFHIPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKTA
AKPPPLPKKKPNYGSLWSLEQSFYIQLVQGSKVNADEGMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWQQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRGAAAEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRY
DIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFA
VNSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMH
VPAVALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMMH
VCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGII
FKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMQSDTIANI
QLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFR
GYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRL
KFNEALRESWKTKVNWLAHNVSKNNRQ
>A0A3B3XCW0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia mexicana|TrEMBL
MDRQQIQVSDEEREVAREESRRRRRKKAITSASSTSMDQISVEFVLPTVARGGSSPDSLL
LEVAGNWTVEQVKAQVWMKAVSLNLCPDFYQRFCPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPTDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPNLYSMDPWVTRKPLPEHLLSKVNNGYILVVIHVSTSSQTIKVSID
DTPSQVLASFFAKTANKRVLLGIPEHLSDEDFVLRVCGREEYLYGEKALQSFNWIRQSLK
NGEEIHLVLETPPDPELDLVQREDWAQVDDCTGVAGTHEQLTIAEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPEFMVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKQPQTPNSKSSYHDNTSGSSTLEGKTKNRLLYYVNLLLIDHR
SLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPK
SREVGRDCGAGSEEGDGGERGQREMPNHLKKQFAAIVSTDPLHPLSPEDKELLWHFRHEC
MRDPRAYPKLLGSVRWGKQEDVLATHRLLDRSNAWDTSGLDVGLAMQLLDCHYSDAQVRS
MAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGENMLQDFRKQVEMTEALQKVTREMKAMSADKYDVTQQ
VVIQLRQKLETLQLSGLPESFRVPYDPGLRAGTLLIEQCKVMASKKKPLWLQFKRADPTT
LSKDPVGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIV
KDATTIATIQQSVVGSTGAFKDEILYQWLRDKCVSEEKFQQAVERFLYSCGGYCVATYVL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKS
SPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSED
EAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A8C7WNN2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias sinensis|TrEMBL
MDRQSIQVSDEEPEVPREECRRRRRKKAITSSSCVSMDQITIEFVMPSAARGGSGPDILT
LDVAGNWTVEQVKAQVWMKAVTLNLCPDFYQRLSPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIPYWRALKKGVGRIQMVTRPQLSEESLQYQRYLNGLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLAKVNNGHILVVIHIGTVSQTIKVSIN
DTPSQVLASFFAKTSNKRVLLGIPDDVCEADFVLRVCGREEFLYGEKPLQNFNWIRQCLK
NGEEIHLLLEKPPDPELDVVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPTLPKVPELVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKPTQTPASKGSSHHDNSAGTGSLEGKTKNRLLFYVNLLLVDH
RSLLRQGEFILHMWKMPEKSDESSSSINADKLTSATNPDKSSSMAVAILLDKYCYPVVLP
KSRDVGRDSGAGEEMEGGERGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRQEC
MRDPRAYPKLLGSVKWGKQEDVLATHRLLERSNAWDTSGLDVGLAMQLLDCHYSDSHVRS
MAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGESMLQDFRKQVEMTMALQKVTREIKAIAADKYDVSAQ
VVFQLRQKLETLQSSGLPETFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTT
LSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETECLDLCLLPYGCISTGNKIGMIEIV
KDATTIANIQQRVVGSTGAFKDEILHQWLRDKCVSEDKFQQAVERFLLSCGGYCVATYVL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKS
SPHFLKFQDVCVKAYLALRHHTNLLIILFSMMLMTGAAPGLAVLLSLHIFNPLTLEMSPV
TPN
>A0A7L2I992|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Semnornis frantzii|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHAPTKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLESPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWRQRLDFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAP
HPVYYPSFEQLLELGRNGEQLRAAAEDPEEKQQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGMIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGQVASLLLKQAIEEFTLSCAGYCVATYVLGIGDR
HSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFE
RFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKH
FRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>Q3UC78|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|TrEMBL
MPPGVDCPMEFWTKEESQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLRVSNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKRATVFRQPLVEQPEEYA
LQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGRITEEEQLQLREILERR
>A0A4Z2BNJ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu bimaculatus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMLKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKYIRSCIIVGRLPHLMLVSKDSLYSQLPASGFVTPSYSRRTPQPSPCP
GGGDGSPPRSLWAFNTPLRVRLLCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRV
PCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYKDIL
VSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFSWFNQTVVFPDEQQIEEHA
NWTISRELGYNYCHGLSTRLACDSSVSTSDAEQLRSLCSKDPLYELSEQEKDFLWRHRHY
CVNIPESLPKLLLSVKWNSRDEVSQVQKHN
>Q8BS14|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|TrEMBL
MPPGVDCPMEFWTKEESQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPMQLEPSARGWRA
GLLRVSNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYA
LQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGRITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQLSQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAI
KSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHV
PSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHM
CMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGII
FKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANI
QLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFR
GYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRV
KFNEALRESWKTKVNWLAHNVSKDNRQ
>S4R1S1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus musculus|TrEMBL
MPPAMADNLDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRRKMRKFSEAKIQSLVGLSWIDWLKHTYPPEHEPSVLE
NLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEDEASPCDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINR
NSSNLPLPLPPKKTRVISHIWDNNNPFQITLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQ
TIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQTNPYAE
NATALHITFPENKKQPCYYPPFDKIIEKAAELASGDSANVVVVEKNFLLC
>A0A7K6IGJ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dasyornis broadbenti|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRVEMPNQLRKQLEEIITTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K4R5V6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neopipo cinnamomea|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFVLPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTADFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPNPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNPDTKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K4QDF8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neopipo cinnamomea|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPVAKGFGT
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPVTLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFHIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A5N3XNV3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Muntiacus reevesi|TrEMBL
VTQGMELENHEQPVVLREDTCRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPET
ALLHVAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVV
QTLDCLHHWKVVHRSPGQIHLVQRHAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFT
RRRLVTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVS
ADDTPGTILQSFFTKMAKKKSLMDIPESQNEEDFVLRVCGRDEYLVGETPIKNFQWVRQC
LKNGEEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWD
CDRKFRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEF
SIKIKDLPKGALLNLQIYCGKAPVLSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLR
HGEYVLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTP
DPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSV
KWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDV
LHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVI
LEAYLRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQN
LNLPQSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGD
DLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTV
GNTGAFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISE
TGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKA
YLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCR
DKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A8D0HRU8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphenodon punctatus|TrEMBL
MPPGIYCPVEFWSNEENQNIQVDFLLPTGIYLSLPISCNASLGTIKQVLWHHAQQEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMRQFCEEKAAKRQQLSWAAWMQYNFPLQLEPSSKGLRS
GSLHVPNKNIFVNVKFESGGESFTFQISPKEYPIMLMSYAIKKQATVFRHQTVESPEDYT
LQVNGKCEYLYGDYPLFQFQYIRSCLHLGLMPHLTMVHSSSILAMRDEQTNCIAHPPKVA
PKPPPIPKKKLTTATLWSLEQPYYIHLVQGSKVNADERMKLVVQAGLYHGNEMLCKMVSS
SEVNMCSEPVWKQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKGGESCLHMWSSFPDEKGELLNPMGTVRSNPNTESAAALVICFPSVTS
YPVYYPSFEHLMELGRSGDYARPMAEDPEEKQQLKEILERRTHTELYEHEKDLVWKMRYQ
ICDQYPEALAKLLIITKWNKHEDVAQMIHLLQCWPELPVLSALELLDFSFPERYVGSFTI
NSLKKLTNGELFQYLLQLVQVLKYESYLNCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSNHHMKVLMKQGEALNKMKALNDIIKASSLKNPKPQTKEFMHT
CMRQETYLEALSNLQSPLNPSIILAKVCVDQCTFMDSKMKPLWIVFDNDESGGTGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGAALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQDSLALGKTDEEARKHFQLKFNEALRESWKTKVNWLAHNVSKDNRQNSLDI
>A0A452QU10|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus americanus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C3NX97|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyanoderma ruficeps|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTNNKHTKAPEILLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEQVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIVQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKEKCLIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A452RJX9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus americanus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRQEYLYGGYPLCQFQYICGCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEELQLREILERRGSGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLRAPGPELPVLSALEAAGLQLPRPHVASFATSTLR
KDDELFRYLLQLVQVLKYESYLDCELAKFLLARALANRKIGHFLFWHLRSEMHVPSVALR
FGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHVCMRQET
YLEALSNVQSPLDPSTLLAEVCVEQCTFMDSKMKPLWLVYSSEEAGSDGSVGIIFKNGDD
LRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSN
MAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRE
NGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERA
YTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEAL
RESWKTKVNWLAHNVSKDNRQ
>A0A8C2DYH9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MEHQASDDEPPVVRREENKRRRRKMKAFTSTSAVSTDNIAVDFVLPTTNKNSRNPDTLHI
DVTGNWTVEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVVRTQPNEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELADRDPKLYSMDPWITPKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFAKIKKKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKN
GEEIHLVLEHPPDPELDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFNEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLLVDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERG
QREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEA
GAITHCLLERSTVWDRSSHDVGLALQLLDCHFSDEKVRTMAVRKLETLEDDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALRSQRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRG
CGEAMLQDFRKQVEMTEALQKVTREIKLMSAEKYDVSQQVVLQLRQKLEGLQTSGLPDSF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFMGISKERVPFVLTPDFLYVMSTTGKKSSPHFLQFQNVCLKAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGCSEDEAKQHFLEQIEICRDKGWTVQ
FNWFLHLVLGIKQGVEKRSA
>A0A7K9YDT6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Odontophorus gujanensis|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMLLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNVWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKANLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLNDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKDRCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8J4U5Q0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Clarias magur|TrEMBL
MNQQKKVLTSPNVCQILWRNARSEPLFSILSDPDAYVFTCINRTAEREDLEDEQRRLCEV
RPFLPVFRLVAREGDRVEKLINTQISLILGKGLHEFDTQKNHEVDEFRAKMRSFCEEKAQ
DRQQLPWNQWMDYNFPCDLEPVSVAAQSGKSHTNVKKIFINVKFEASEESFMLQLDPQDL
PVVLMKSALRKKATVFRSVKQEKPEEYTLQVNGRWEFIYGKYPLCRFKYIFSCLYGGLTP
HLTMVHHSTISKYKEEQGGLSNQVSKSRSQSKPPPLPLKKQNTSSLWSIHENFHIHLLQG
TRVNADESMKLVVQAGLFHGSELLCKVVTSSEVSVCSDPVWDQKLAFDIPLCDLPRMTRL
CFALYGVLDKPRKQRSTKKKNKKADCPLAWVNTMVFDYKDQLKTGEIFLSTWPSAPDDKG
DLLNPMGTVERNPNMDSSAGLHIRFPSFRPHPLYYPPLEKLNEVNGDKAGATKEEHLKLK
EIVDNKNHTEFFEDEKELLWKLRGEMRANYPESLSKLLLITKWNKHEDVAQIVALLRKWP
DLPALHALELLDYSFPDPHVRSFTIRCLRKLRDDELFQYLLQLVQVLKYEPYLDCDLTTF
LLDRALSNKRIGHFLFWHLRSELHVPSVSLKFSLILEAYCRGSIYHMKSLMKQNEALSKM
KALNDFVKSGSQKSASRSQITEDMKLCIKQDTYLEALSGVVSPLNPSIILSEICTDKCKF
MDSKMKPLWLMYKNKCVQTDTLGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMIP
YGCLSTGNKTGLIEVVKNSDTIANIQRNKSNSAATAAFNKDALLDWLKSKNPGDKLDKAI
EEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKAKFGINRERVPF
ILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMRAAGLPELSSS
KDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKKPEVPVSSYYMLGVVLRSGKPV
GGASGPGGMNREEAPGKSPEEMYIQQKVRVLLMLKKMGSNLTPSEEAFLRNYAGVVHSQM
SQLPQHNIDQ
>A0A669QWM7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phasianus colchicus|TrEMBL
WCLNRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVTALVTLI
CSFLDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISL
LIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLG
TGLLHTPTKNIFVNVKFQSGGVNFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDY
TLQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINSIANPPKM
AVKPPPLPKKKVKGHNRSSPCGFMVFSYFFSPQLVVQAGLFHGNEMLCKTVSSSEVNVCS
EPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFD
YKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALLICFPNVASHPVYYPS
FEQVGNTDVFLRGESLASLQLKEILERRSHTELYEHEKDLVWKMRHDIRDQYPQALAKLL
TITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQ
YLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEA
YCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQETYLEALSH
LQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTL
QMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFN
KDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHID
FGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYMILRRHG
PLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKV
NWLAHNVSKDNRQ
>A0A8C2BS27|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MEHQASDDEPPVVRREENKRRRRKMKAFTSTSAVSTDHIAVEFVLPTTNKNSKYPDTLHL
DVTGNWTVEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVIRQQPNEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDPKLYSMDPWITPKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAISDFHWIRQCLKN
GEEIHLVLEHPPDPELDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFNEEVLWNTWLEFNIK
IKDLPKGASSMADAILLDKYCYPVALPKSKDSPDSEMEGERGQREMPNHLRKQFEQIIAT
DPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEAVAITHCLLERSTVWDRSS
HDVGLALQLLDCHFSDENVRTLAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALARFL
LKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGEAMLQDLRKQVEMTEA
LQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDSFKVPYDPGLRAGALVIEQC
KVMASKKKPLWLQFKRADPTTLSRDTIGIIFKDGDDLRQDMLILQILLIMESIWELESLD
LSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDEILSQWLSEKCVNEDKH
QQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFMGISKE
RVPFVLTPDFLYVMCTTGKKSSPYFLQFQNVCLKAYLALRHHTNLLIILFSMMLMTGMPQ
LSSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQFNWFLHLVLGIKQGVEKR
SA
>A0A669QWD7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phasianus colchicus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C1CAH8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
LFDDEPPVVRREENKRRRRKMKAFTSSSAVSTDHIAVEFVLPTTNKNSKYPDTLHLDVTG
NWTVEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTLDCIR
YWKALRKEVGKIHLVIRQQPNEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRKLLTP
RKIELSDRDPKLYSMDPWITPKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDDTPVQ
VLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAISDFHWIRQCLKNGEEI
HLVLEHPPDPELDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRKFRV
KILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIKIKDL
PKGARLSLQVSCGKAQTQTSKENECKNKTRLLYYVNLLMVDHRSLLRQGEFILHMWKMPE
KSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERGQREM
PNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEAVAIT
HCLLERSTVWDRSSHDVGLALQLLDCHFSDENVRTLAVRKLETLEDDDVLRYLLQLVQAV
KFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGEA
MLQDLRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDSFKVPY
DPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSRDTIGIIFKDGDDLRQDMLILQI
LLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDEIL
SQWLSEKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDFGH
ILGNYKSFMGISKERVPFVLTPDFLYVMCTTGKKSSPYFLQFQNVCLKAYLALRHHTNLL
IILFSMMLMTGMPQLSSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQFNWF
LHLVLGIKQGVEKRSA
>A0A8D0F2V3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strix occidentalis caurina|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKDDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRTTTSVWDVSNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQSINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFHIVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSIQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K6EMW4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Grantiella picta|TrEMBL
MELGNHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTSLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESVKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A4X2MAU7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vombatus ursinus|TrEMBL
MPPGVDCPMEFWSKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVARQGDRVKKLINSQISLL
IGKGEPAGRTATSTGGGPHRCGRAVSQPGSSPGLHEFDSLRDPEVNDFRTKMRQFCEDVA
VRRQQLGWEAWMHYSFPLQLEPSARGVGAGTLRVPNRTLLVNVKFEGNEESFTFQVSPND
FPLALMACALKKRATVFRQSAMERPEDYTLKVNGKCEYLYGGYPLYQFQYICNCLHKGLT
PHLTMVHSSSILAMRDEQSNLTAQAPKLRAKPPPIPVKKPSSVSLWSLEQPFCIELVQGS
KVNADERMKLVVLAGLFHGNEMLCKTVSSSEVTVCSEPVWKQRLEFDINICDLPRMARLC
FALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGECCLYMWSSVPDEKGE
LLNPMGTVRSNPNTESAAALVICIPEVAPHPVYYPTMEKILELGKNGEHGRFTEDELQQL
REILERKVAAELYEHEKDLVWKMRHEIQEQFPEALARLLLVTKWNKHEDVAQMLFLLGSW
PELPVLSALELLDFSFPDRHVGSFAIQSLRKLTDDELFQYLLQLVQVLKYESYLDCELTK
FLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSNHHMKVLMKQGEALNK
MKALNDFVKVSSQKTTKPQTKELMHVCMRQETYLEALSNVQSPLNPSTLLSEVCVEQCTF
MDSKMKPLWIVYSNEEAGGGADSHVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLR
MTPYGCLSTGDRTGLIEVVSHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALE
RAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRER
VPFILTYDFVHVIQQGKTNNNEKFERFRSYCERAYTILRRHGLLFLHLFALMRAAGLPEL
SCSKDIQYLKDSLALGKTDEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A668VRQ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKSKNIKKIFINVKFEASDVSSSVVDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQV
NGRWDFIYGKHPLCQFKVSSEKINSLFSSDFFPQQNTSSLWSINEPFHIHLVQGKRVNAD
EGMKVVQAGLFHGSELLCKVVTSSEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGV
IEKTKKPRGTKKKNKKAVSDCPIAWVNTMVFDYKDQLKTGEFHLSTWPDLLNPMGTVEKN
PNVDSAAELLIHFPNIRPHPLYYPPLEKVPSPKRLHKTYFKLKEIMDNKNYTEFFEDEKE
LLWKLRTEVRDHYPESLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPD
PAVRSFTIRCLRKLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFW
HLRSETHVASVGLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAE
DLKQCIRQESYLEALSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMV
GIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTI
ANIQRNSSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDR
HNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFE
RFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKN
FKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A553PXT6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Danionella translucida|TrEMBL
MPPGVYGMQEVWEQDGLHQISMEFLLPTGIYLNFPVAISDTIGTIKKMVWKNAKNEPLFG
ALRDPDAYVFTCISLSAEREELQDEQRRLCDVRPFLPILRLVAREGDRVEKLITTQINQL
IGKGHYEFDSRKNHEVNEFRSKMRTFCEEQAQSRQMLQWCKWMEYNFPCDLEPVSVVAQT
GKSRSTRILVNVKFEGSEESFVLQQDPHDFPLVLKNNALRKKSTVFRRTKHEEPDDYTLQ
VNGRWEFIYGKYPLCRFKYIFTCLHGGLTPYLTMVHHSAITKYQEEQGSLSNPVSKIHTQ
SKPPPLPLKRQQNTCSLWSIQEPFHVYLIQGSRVNADEGMKLVVQAGLFHGSELLCRVTS
NEVNVSSEPFWDQKLVFDINVSDLPRMSRLCFALYGVVEKTKKRPTKKKNKRADCPLAWV
NTMVFDYKDQLKTGEFSLSTWPSIPDDKGDLLNPMGTVEKNPNIDSSAGLLIRFPNIRPH
PLFYPPIEKHQKLKEIADNKNHTEIFEDEKELMWKLREEVRELYPESLSKLLLITKWNKH
EDVAQMVGLLQRWPDLSVLHALELLDYSFPDPHVRSFTIRCLRKLHDSELFQYLLQLVQV
LKYESYLDCHLTSFLLERALANKKIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGSIHH
IKCLMKQNEALNKMKALNDFVKSASLKASRVQTIEEMKVCIKQDNYMGALSGIVSPLNPS
IILSELGADKCKFMDSKMKPLWLMYKNKYDTVGIIFKNGDDLRQDMLTLQMIQLMDVLWK
TEGLDLRMQPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNNAATAAFNKDALLNWLKSK
NPGDRLAHAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSK
FGINRERVPFILTYDFVHVIQEGLTNNNEKFERFRECCEQAYKILCRNGTLFVNLFVLMK
AAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHAFAKDN
R
>A0A668REK6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MAPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLTTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYSKLDKGQIIVVIWVIVSPTNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPME
FFTMPSYARRISTATPYMNGETATKNLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLTYDMYIPEVPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHY
SSPVKFPDMSTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHDCINMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMVREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A091SVX9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pelecanus crispus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7L0JYI4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chauna torquata|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKIPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTADFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIHVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKVTNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEMWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMDIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A091STE2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pelecanus crispus|TrEMBL
DSIMPPAVTDSLDIWAVDSQVGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HTYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSYNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAINP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHIEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTIQILRLMDVLWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8D2IET4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Urocitellus parryii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K7MLN4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Brachypodius atriceps|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLDTIKQVLWKQAQYEPLFH
MLSDPDAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSDFRSKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVRFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETLQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKAA
CKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVAVCSEPVWRQRLDFDIGVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P7KYF9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Betta splendens|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMLLTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEADLEEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNIINVCKEAVELKDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYYQLPMD
NFTMPSYARRISTATPYMNGETATKPLWSINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMATIEEHANWNISRELGFNYCHTGLTNRLARDNPLTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCVNLPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHTMN
>A0A7J7ENL4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Diceros bicornis minor|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVARNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRSKMRQFCEEAAACRQQLSWEAWLQYSFPLQLEPSAGSWGA
GTLRVPNRGLLVNVKFEGSEESFTFQVSTKEVPLALMAYALRKKATVFRQPLVEQPEDYT
LQVNGKLEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHHSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIQLIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAATLVICLPEVAP
HPVYYPALDKILELGRPGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKATKPHTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSHGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRSYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEXXXXHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A4W3GIB4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MENKTNIEKNDELPIVMREENKRRRRNMRANTTRGMQYYSLEQLSIEIILPTRNKRTAMH
EKISLDIAGNYTVEQLKTKIWVKANGTSGSPEYYQKFSPDQFILLYQKKGQWYEIYDKQQ
VIQTLDCINYWKVLQKSVGKIHVVQKARSSDQSLQLQWDLNNLVGYDVTDVSNVHDDELE
FTRRTLITPRLTEVATRDVRLYSMDPWILSKPLPEYLLNKISGNNIFMIIHRGAVSLTIK
VSIDETPESILRNFFKKMAKKMSLLDMNESHSEEHFVLRVCGRDEYIVGDNPIKDFFWIR
NCLKNGEEIHLVLDLPPDPVLDEVQKEEWPLVDDCTGVTGSHEQLTLEGKDHEKVFTISL
WDCSQTFRVKIVGIDIPVLPRNTDVTVFVQASILHGQQILAQQRTPAKAFTEEVMWNMWL
EFDIKVKDLPKGARLNLQVYCGKAQALGSKALEDLWDSRSKNNMLYYVNLLVIDHRSLLR
QGEYLLHMWKIPNKGEEQGTIEADKLTSATNPDKQTSMAICILLDRYNYPIALPRSRQTD
PEAERSGPEMHSQLRKQFEEIVSTDPLNPLSAEDKELLWHFRHECVKQPKAYPKFLSSVK
WGQQDVVLKTHQLLQKQTAWASSPLDVGLALQLLDCRFSDEQVRTMAVQKLETFGNDDVL
RFLLQLVQAVKFEPYHDSALARFLLKRALGSKRIGHFLFWFLRSEVSESMHYRQRYAVML
ECYLRGCGQAMLMDFMKQVKVIKELQKLTKEIKNVTADKYDISSQAISQLRHRLEKLQSS
GFPECFRVPYDPGLRAGALVVDKCKVMASKKKPLWLEFKCADPTSVSKDTIGIIFKQGDD
LRQDMLIIQILLIMDSIWEMESLDLCLLPYGCIATGNKIGIIQIVKDATTIAKIQQSTVG
NTGAFKDEVLNHWLKEKCVIEEKFQSAVEKFVFSCAGYCVATYVLGIGDRHNDNIMITES
GNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLFVMGTYGKKTSPHFQKFQEICLKAY
RTLRHHANLLIILFSMMLMTGMPQLTSKEDIEYIRETLTVGKNEEEARTHFLEQIEICRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A4W3K7D3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MESLNRDGHSQANTSSGKVEEEYNQCEFNSFMNLSTVVFDCVLPTKKLNDDQNEVITVEI
PGNSTVRHLRILTWMQATRDSASPSIYTLTHPNSYQFLYKKGLRWYEIYDDHQIIQTLDS
VRYWKNSGMKKGSIYIKSNPKETEESDKLQKKLTYLIGYDIRNIVTHRRNELSFAQRKLA
SSRQVELSSRDVRAYAMEPWVVSSPLSKSLMDLTGEGLVIAIHYNDSSHKMKVGITDTPV
EIIHSYMQKMADKGWPIHHPEDNLAFKVCGREEHITGGRPLIDFIWIRRCIKNKEDIRLM
LVLAPCTEDDEVDTDDWPLVDQHTGLCGTHDELTLRNKDIDQILVLSLWDCNSRFRVKVV
GIDCPALPHKSLPHIYVEACILHAKTILSSARSQPLPFTEEVIWNIWLQFDILVKNLPRG
SRLSFFIYGMDFESLSTRDAKTPPQRVEDGGFYKGRTKLLYFVSFLLIDHRSFLQQGEHI
LHMWPYADREEDLFTHEADKLSSKTNPDVDNSMAICIMLDTYSHPLVLPTGRTSRSSCIN
QMSEDAELTSTMNIRCKKLPLPLTVSEKNLQFTEQCSQYGNSLPNILSSVKWGKLEAVEE
AHCLCEHWNSQQLDIAIALELLSISFADEKVRNLAVQRLEELDNNELLRYLLQLVQVTLL
PGSKRIGHFFFWYLRSEITGSPYFCDRFAVILEAYLLGCGKSMLDEFYKQVQVVESLHQV
ATDIKKIIPEKNDLPPNAASLLQDMLRKADLPQSFLVPYDPRIKTSGILLERCRIMASKK
KPLWLEFSCGDEDSAHCQPVGIIFKHGDDLRQDMLIIQTLVIMDSIWQENSLDLNLVPYG
CISTGYNIGMIEIVRDATTIAAVQRSQGGTTAAFKNEALHEWLRSRLQVEESYYQAMETF
VTSCAGYCIATYILGIGDRHNDNIMVTAQGNLFHIDFGHILGNTKRFLGVNRERAPFVLT
PDFLFVMGKVNKRSSLYFQRFKDICIEAYLSLRAHSKLLVNLFSLMTLTGIPELTSTKSI
QYLKEALAMEKDEKMAQEHILNQIEMCESLGWTVQANWWIHMFMGVKQTKS
>A0A3B4DX06|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pygocentrus nattereri|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLISVKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPSVESSPQLPQH
IYCKLDKGRLIVTIWVVVSPSNAKQKYTLKISHDCLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKSAPALRHIRQRQHPRHRQDLREDRYLSRRRASM
>A0A2U3VQZ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Odobenus rosmarus divergens|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRSKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTVRVPTRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLYQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFRVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALSDFVKVSSQKTTKPQTKELMHLCMR
QETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDTQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A6P6D5F5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Octodon degus|TrEMBL
MPPGVDCPMEFWTKEENQSVMVDFLLPTGIYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVDQTAEQQELEDEQRRLCDVQPFLPVLRVVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRTKMRQFCEDAAARRQQLGWEDWLQYSFPLQLEPSARSGGP
GALLVPNRALLVNVKFEGSEVSTKDVPLALVACALRKKATIFRKLLVEQPEDYALQVNGR
HEYLYGSHPLCRFQYICSCLHNGLTPHLTMVHSSSILAMRDEQDDPTPQVQKPRPKPPPI
PSKKPSSVSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGHEMLCKTVSSSEVSVC
SEPVWKQRLEFDISICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAWANIMLF
DYRDQLKTGERCLYMWPSAPDEKGELLNPAGTVRGNPNTESAATLVICLPEVASHPVYYP
ALEKILELGRHGEQRGHITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQENFPEA
LARLLLVTKWHKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTD
DELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFG
LIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQAKELMHLCMRQETYL
EALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEASSTGSVGIIFKNGDDLR
QDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMA
ATAAFNKDALLNWLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESG
QLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGYCERAYT
ILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRE
SWKTKVNWLAHNVSKDNRQ
>A0A6P3EIN3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Octodon degus|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIACDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLLDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEEKIQSLVGLSWIDWLKQTYPPEH
DPSTLENVQDKLYGGKLIVAVHFENSQDVFSFHVSPNMNPIKVNELAIQKRLTIHGKEDE
ARPADYVLQVIGRIEYVFGDYPLIQFQYIRNCVVNRALPHFVLVECCKIRKMYEQEMIAI
EAAINRNSSNFPLPLPPKKTRIISHVWDNNKPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIISSEISGKNDHIWNETLEFDINTCDLPRMARLCFAVYAVLDKAKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPDNKKQPCYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSIQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLQQSAYREALSDLQSPLNPCIILSELHIEKCKYMD
SKMKPLWLVYTNKVFGEDSVGVIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRKHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKTDEEALKQFKQKFDEALRESWTTKVNWMAHTVRRDYRS
>A0A8C6UYA5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neogobius melanostomus|TrEMBL
MCFKLFSVSRQLLWKQAQSFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFL
PVLKLITRNCGRAERLLDSKIGVLIGKGLHELDAINDQEVKDFRGKTLRQSEEKMQKVQM
MSCTEWLQASFSQQLEPGPGPDQINGVSDRSTDLKVTIHFDQSQDSASLKVPLSCTPPEL
MDMAVRKWLTTHGPEKEASRGQYFLRVSHSLEFLCGDDPLSHYKYIRTCVQTKEPPHLTL
VHSLCHRSVVSRKSLPLPLPPKRRTPTHIQTCVWDVSSPFKIVLVNASKVNAEETAKVKY
VSSLVIKFHGFLLCKPAVSSESSGRSEHTWRDSTLEFEISVCDLPRMTRLCIAIYAVMDK
VKNSPGLCQLKTGDIILHCWSSFPDELEEMLNPIGTVQTNPYTENATALHISFPEYLPHA
IVFPPFDKILEKAAQIARASDCSPMGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLR
YDCRENFPQSLPKLLLSVKWSKHEDMAQLQVLLQIWPKLSPRDALELLDFNYPDQYVREY
AVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQRNRKIGHFLFWHLRSEL
HMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKFGTMKNARSKAKEAM
LTKEAMMTCLRQSGYYETLSDIHSPLNPNILLAEVNVERCRYMDSKMKPLWIVYNNKLLD
GDTLGIIFKYGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRAGLIEVVSS
ADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDHAIEEFTLSCAGYCVATYVLG
IGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYT
EKFASFRQYCEEAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDDE
ALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A1S3MDG3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo salar|TrEMBL
MPPGEYGMLGEWKKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRPFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPMILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTIVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVV
TSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKTKKPRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPHFDKLRDLEKNGGKVIATKVEHMKLKEIVDNKNYTEFFEDEKELLWKLRGVV
RERYPESLSKLLLITKWNKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTIS
CLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLKSEMHVS
SVSLRFGLILEAYCRGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLC
IKQEAYMEALSYLLSPLNPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIFK
NGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQR
NNSNSAATAAFNKDALLNWLKSKNPDRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDN
IMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRE
CCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVK
FNEALRESWKTKVNWMMHSLAKDSRL
>A0A1U7T788|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carlito syrichta|TrEMBL
MELETYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTCQRHSKSPETVLLH
VAGHGNVEQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWKVLHRSQGQIHVVQRHPPSEETQAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVARRDPKLYAMHPWVTSKPLPEYLSKKIANNCVFIIIHRSTTSQTIKVSADDT
PSTILQSFFAKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIRNFQWVRHCLKNG
EEIHLVLDSPPNPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKTPALSGKASAETPSSDSKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQIPSKGEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGH
QETVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTEQVQVIEMLQKVTLDIKSLSVEKYDVSSQVISQLKQKLENLQNSNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCSDTTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGRNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A6P7ZWV0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcaecilia unicolor|TrEMBL
MPPGVYFPADFWAKEQNKNILIDFLLPTGIYITFSVPRNASLGNIKQSLWHHAQYEPFYH
MLSEPQAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVQKLINSQISLL
IGKGLHEFDSVGDQEVRDFRSKMRQLCEEKAAERQQLGWEAWMEYSFPRQLEPSARLLNM
GIYHTNSKNIIVNIKFESSEESFTLQISPKEFPLALVRSALKKKALVFRQQDRGEPEDYT
LKVNGSSDYIYGQYPLCQFKYISGCLYRNLTPHLTLVPTSSVKVLRDEQESLQVSKLRSK
PPPLPVKKLSPVSLWNFEQTFCVKILQGSNVNADECLKLVVQASLFHGSEMLCKTVRTAE
VSVSSEPVWNQMMEFDISICDLPRMSQLSFILYAVEKAKKVRSTKKKSKKADCPIAWVNT
MVFDWNDMLKMGECCLYMWSSAPDDKGELLNAMGTVQSNPNTESAVALRICFPSISQHPV
YYPPLEKILELGKQGERQHSTIEEQQQLKELLERSVELYEHEKDMLWKLRHEIREQYSEA
LAKLLLITKWNRHEDVAQMLYLLQSWPELPVSCALELLDYNFPDHCVRDFAVNCLKKLTD
EELCRYLLQLVQVLKYESYLDCELTIFLLERALASRKIGHYVFWHLRSEMHVPAVALRFG
LILEAYCRGSHYHMKVLVKQVEALTKMKALNDIVKISSQKPTKPQTKELMHVSLKQENYQ
EALSNLQSPLNPSVILGNVCVDLCTFMDSKMKPLWIMYNNNEMNQNRVGIIFKNGDDLRQ
DMLTLQMIHLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEIVGHSDTIANIQLNKSNMAA
TAAFNKDALLNWLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQ
LFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRKYCEKAYTV
LRLNGTLFLHLFVLMKAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRIKFNEALRES
WKTKVNWLAHNVSKDNRQ
>A0A7L1UUH1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sitta europaea|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAMEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKTSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKYKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRTSSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGRAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8J7NZL2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Atractosteus spatula|TrEMBL
MPPRILVDCLLPNGMILTLECLREATLVTIKHELFKEARKYPLHHLLQDETSYIFVSVTQ
EAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPE
VQDFRRNILNVCKEAVDLRDANGPHSRALYVYPPNVESSPELPKHIYNKLDKGQIIVVIW
VIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQGKYILKVC
GCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKESLYSQLPIDNFTMPSYARRISTAT
PYMNGEASTKSLWSINSNLRIKILCATYVNVNIRDIDKIYVRTGIYHGGEQLCDNVNTQR
VPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHT
LVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDFFSSPVKFPDMATVEDH
ANWTVSRELGFNYCHTGLLRLVCNRDPLSEITEQEKDFLWRHRHYCVNMPEILPKILLAV
KWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYL
IQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYC
RACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFT
SPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDML
TLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQF
NSHTLHQWLKDKNKGEMYDLAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHI
DFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIR
QHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWT
TKMDWIFHTIRQHALN
>A0A8C3QDJ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geospiza parvula|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3Q2UNI5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fundulus heteroclitus|TrEMBL
MPPAMTDLLDIWANDSPLAGHAPDQITMDFLLPTGIYIQMDVPREATIKHIKLLLWKQAQ
NFPLFSSLGEMENHMFECVNQAAVHEELEDESRRLCDVRPFLPVLNVVIRNRGRPERQLD
SKIGKLIGKGLHELDAINDQEVKDFRSKMARCSEEKMRQAQTMTCMEWLQACFSPQLEPA
ALTTITDGHNEQPADLKVFIHFDQSQDSTSLKVLSSCTPSELMEMAVKRWLITHAPEEEA
YRGQYVLRVSQCLEFLCGDHPMIQYKYIRTCLQAKKPPHLTLVHTSTIERMFKKEMSAIG
DLVSRKSSDPPLPLPPKRRGPTQVQTCVWDVSSPFKIVLVKGIKVNAEESAKVQVRAGLF
HGTELLCKPAVSTESSGRSEHTWKDNVLEFEISVSDLPRMTRLCFAIYAVMDKVKKQKST
KNPHTNKSQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYPENATALHIHFPELHSHPVVFPPFDKILEKAAQIHRASDNVSIGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRHDCHENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLCPRDALELLDFNYPDQYVRKYAVNCLRDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAQSNRKIGHFLFWHLRSEINMPAVSVQFSLILEAYCRGSIPHIEVLQKQVDALT
KLKSVNELIKLGTIKNARSKTKEAMLTKEAMMKCLRQSGYSEALSDLSSPLNPSVLLSDI
NVEKCRYMDSKMKPLWIVYNNKLLVGDTLGVIFKNGDDLRQDMLTLQILRLMDLLWKEEN
LDLRIVPYGCLATGDKAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSG
DALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQEGKAGNTEKFGSFRQYCEDAYLILRKNGNLFITLFALMLTAG
LPELTTVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A6P4WNA7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera pardus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GPLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLLERPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSAILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSAPDEKGELLNPAGTVRSNPNTESAAALVICLPEVSP
YPVYYPALDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPDLPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMRQGEALSKLKALNDFVKVSSQKTTRPQTKELMHLCMR
QETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDSSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGPLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A452FD91|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Capra hircus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRIPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVCSQKTPKPHAKEMMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ETAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A1S3GN09|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dipodomys ordii|TrEMBL
MELEHHDQPVVLREDNHRRRRRMKPRGAAASLSSMELIPIEFVLPTSQRHSKTPETALLH
VAGRGTVAQMKAQLWLRALETSVAADFYHRLGPDRFLLLYQKKGQWYEIYDKCQVVQTLD
CLCHWKGLRRSPGQIHVVPRHAPSEETLAFQRQLTALIGYDVTDVTNVHDDELEFTRRRL
LTPRMAEVAGRDARLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSADDT
PGCILRSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKMG
EEIHLVLDTPPDPARDQVREEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRR
FRVKIRGIDIPVLPRNAELTVFVEANIQHGQQVLCQQRTSPKPFTEEVLWNAWLEFRIRI
KDLPRGALLNLQLYCGKAPALSAKAESPGAESRGRVQLLYYVNLLLIDHRGLLRHGEYVL
HMWQISAKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHCPTPDPEGDR
VRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQE
MVAKTYQLLTRKEIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLEGLEDDDVLHYLLQ
LVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLR
GCGTAMLQDFTQQVQVIEMLQKVTIDIKSLSADKYDVSSQVISQLKQKLENLQNSNLPQS
FRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDM
LILQILRIMESIWETESLDLSLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAF
KDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFH
IDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVKAYLALRH
HTNLLIILFSMMLMTGMPQLTSKEDIEYIRGALTVGKNEEDAKKYFLDQIEVCRDKGWTV
QFNWFLHLVLGIKQGEKHSA
>A0A2Y9KF36|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Enhydra lutris kenyoni|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRRQLGWEAWLQYSFPLQLEPSARGWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCLR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A6J1ZI66|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acinonyx jubatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A4X1V4Z1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8D1H663|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQL
PMDCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVR
TGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKE
EHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEF
DWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTR
DPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQ
AMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKA
LTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTD
ILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKR
PLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYG
CLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLF
TRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLT
QDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFD
DIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A4X1W7Q4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPGVDCPMEFWTKEENQSVDVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLHDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSDPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPRHWPGCCWSPSGTGTRTWPRWVTRVGPGRGRARSQMAVTSPAPCPDYLLPQMLYLLC
SWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCEL
TKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEAL
SKLKALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDPSILLAEVCVEQC
TFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLR
MTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALD
RAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRER
VPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYAILRRHGLLFLHLFALMRAAGLPEL
SCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7F8RY45|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptonychotes weddellii|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTMRVPTRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFRVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLNMWPSVPDEKGELLNPTGTVRSNPNTESAAALIICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALSDFVKVSSQKTTKPQTKELMHLCIR
QETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDTQYLKCGRSWGVGRVVGHEPLCGAWF
MHNDAAPSSAPPVQKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7F8QUZ4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptonychotes weddellii|TrEMBL
MCFGFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECFKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
HPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVDCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLR
>A0A6P3RG65|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pteropus vampyrus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQFEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLSLMACALRKKATVFRQSLVEQPEDYA
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHCSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIQLIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVNVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRASGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELAKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPQTKELLHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSEGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A6J1UWY3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Notechis scutatus|TrEMBL
MELETSDQAVVMRDDNKRRRRRRMKPYCTANTLSSTELISIEFVFPTTSIVLDIPTNCTV
EQMKTQVWMRAVEGHQTSDLFRKITPDQFLLLYQKKGQWYEIYDKYQIIQTLDCILYWKV
LQKKVGKIHVVEKPNPSDEVQDFQNQLNYLIGYDVTDVSNVHDDELEFARRRLVTPRTIE
VSCRDPKLYSMSPWTTSKPLPEYLLSRIANSNIFINIHRGTTSQKIKVAVDDTPDVILQS
FFTKMAKKKSLMNIPEDYSEQDFVLRVSGRDEYIVGETPIKNFHWIRQCLKKGDEIHLVL
DEPPDSNQDEVQKEEWPLVDDCTGVSGYHEQLTIHGKDHERVFTISLWDCNRKFRVKIIG
IDIPILPRNTDLTVFVEANIQHSQQLLSQRRTTAKPFTEEVLWNVWLEFDIKIKDLPKGA
LLTLQIYCGKTPLPSTKGNLHPQDSPSTDPKYKTQLLYYVNLLVIDHRSLLRTGDYVLHM
WKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHKIASDPPEGRAR
VEMPNQLRKQLEEIIATDLLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWGEQKLV
TETYQLLAKREAWDQSALDVGLPIQLLDCNFSDETVRTMAVQKLEGLEDDGVLHYLLQLV
QAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGC
GKAMLKDFLRQVQVTELLHKVTREIKAISAEKYDITPQVIAQLKQKLERLQDNKFPECFR
VPYDPGLKAGALMIEKCKVMASKKKPLWLEFKCADPTSLSSETIGIIFKHGDDLRQDMLI
LQILRIMASIWEEESLDLCLLPYGCISTGNKIGMIEIVKDANTIAKIQQSTVGNTGAFKD
ETLNQWLKDKCVIEEKFQSAVERFVYSCAGYCVATFVLGIGDRHNDNIMITGSGNLFHID
FGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLRFQNFQDICVRAYLALRKHT
NLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKHEEDAKKYFLDQIEVCRDKGWTVQF
NWFLHLVLGIKQGVEKHSA
>A0A4V5PB94|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodon monoceros|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPLKKPVSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDISIGDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPIYYPALDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C5YJ54|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcebus murinus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A1U8CBT5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mesocricetus auratus|TrEMBL
MELGNYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFILPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDHFLLLYQKKGQWYEIYDRYQVVQTLD
CLRYWKTMHKSPGQIHVVQRHAPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDARLYAMHPWVTSKPLPDYLSKKIANNRIFIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
GEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHDSVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPTLSSKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRHGDY
VLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIGTDPLNPLTAEDKELLWHFRYETLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGMAMLQDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSSLP
KSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETECLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVRAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>B2GU76|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus tropicalis|TrEMBL
MELDSYEQPVVLRDENQRRRRRMRPHSATSNMFPMEQIPIEFILPTSNRCSKVQETMLLE
VAGNCSVEQMKAQIWMHAIEKSHNSDFYQRLTPDQFLLQYQKKGQWYEIYDKHQVIQTLD
CIMYWKVLQKTVGKIHIVQKEKIPEEMIEYQKTLNYLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIELSRRDARLYSMDPWVTCKSLPEYLCQRIISNSIFIIIHKGMTSHTIRVSIDDT
PDVILHSFFTKMAKKKSLLDISEENSELDFVLRVCGRDEYIIGNAPIKDFHWIRQCIKNG
QEIHLVLEKPPDPLMDEVQKEQWPLVDDCTGVTGYHEQLTIEGKDHEKIFTISLWDCNRK
FRVKIIGIDIPVLPKNTELIAFVEANIQHGQQVLSQRRTTCKPFTEEVLWNSWLEFDIKI
KDLPKGALLNLQIFCGKAPTASNKSIVQSPESTASDSKCKNQLLYYVNLLLIDHRFLLRQ
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKETSMAISISLDKYCHPVALPKHKLVCD
PELERPRTEMPNQLRKQLEEIIATDPLHPLTPEDKELLWHFRSEIVKHPEAYPKLLSSVK
WGQQEMVAKTYQLLSKREAWDDCSLDVGLTIQLLDCNFSDENVRAMAVQKLESLQDDDVL
HYLLQLVQAVKFEPYHDSALSRFLLKRALQSKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLDDFTRQVQVTEILHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQNS
KLPDKLPDSFRVPYDPGLRAGSLVVEKCKVMASKKKPLWLEFKCSDTTALSNETIGIIFK
HGDDLRQDMLILQILRIMGSIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAQIQQ
STVGNTGAFKDEVLSQWLKEKCPIEEKFSAAVERFVYSCAGYCVATFVLGIGDRHNDNIM
VTESGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSQYFNKFQDVC
VKAYLALRHHTNLMIILFSMMLMTGMPQLTSKEDIEYIRDSLTVGKNEESAKKHFLDQIE
VCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A2I4BRT7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Austrofundulus limnaeus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVMRSCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRISEEKMQRVQMMTCAEWLQACFSPQLEPA
AAMAVTDEVNDRPPDLKVIIHFDQCQDSTSLKVSSSCTTSELMEMAVKKWLTTHAPEEEA
WRGQYFLRVSQRLEFLCGDHPLTQYKYIRTCLQAKEPPNLTLVHTSTVKAIFDKEMSAIG
AVVSRRTSNPPLPLPPKRRVPTLVQKYVWDVSSPFRIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSSESNGRSDHTWKDSTLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKST
KNAHINKYPTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDITLHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHSIIFPPFDKILEKAAQIARASDCASIGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLDRAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALS
KLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSDALSDLHSPLNPSVQLSDI
NVEKCRYMDSKMKPLWIVYSNKLMSGDALGIIFKNGDDLRQDMLTLQILRLMDLLWKEAN
LDLRIVPYGCLATGDRTGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSG
DALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEDAYLILRRNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDDDALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8B9HBL1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDVNGPHSRALYVYPPNVESSPELPKH
IFGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKVNSLSVIFTQNAPAMKLYLILPVKYVKLV
VGLYLVHNNTTVNVFHAGSSGCDLAVYIVWALYYLLLICNLYSVIIYLPSILFTFVLFSA
LTICADQETPCLELEFDYFSSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDH
IITEADIDQLRQLANRDPLSEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVA
QMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKY
EQYLDNPLVRFLLKRALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKH
LSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQL
GNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIME
NIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWL
KDKNKGETYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHK
KKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFIN
LFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFH
TIRHHAQN
>A0A8C4TZ29|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Falco tinnunculus|TrEMBL
MPPGIYCPTEFWAKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLHISTKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKTT
PKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKNNLTVLDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSE
MHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEM
MHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVG
IIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIA
NIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFER
FRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHF
RLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8B9J8N6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDVNGPHSRALYVYPPNVESSPELPKH
IFGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKVNSLSVIFTQNAPAILAVYIVWALYYLLL
ICNLYSVIIYLPSILFTFVLFSALTICADQETPCLELEFDYFSSPVKFPDMATIEDHANW
IISREMGYNYCQSGQSSRLARDHIITEADIDQLRQLANRDPLSEITEQEKDFLWRHRQYC
VNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRC
LEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTNQRIGHFFFWHLKSEMHNK
TVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQ
MRRPDYMDALQSFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNE
IIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIM
QIQCKGGLKGALQFNSSTLHQWLKDKNKGETYDMAVDLFTRSCAGYCVATFILGIGDRHN
SNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREF
ERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQEALD
YFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A8B9H9Q3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MEQHISDDEPPAVPREENNKRRRRKMKAFTSATSVPVDHLVMEFVLPTTNKTTKNPDTVQ
LEVLGNWTVEQVKAQLWLRAVATNLCPEFYQKFSPDHTILLYQKKGSWCEIYDKHQVFQT
LDCIRYWKALKKEIGKIHLVLRPQSSEESVQYQKFLNHLIGYDVTDVSNVHDDELEFTRR
KLLTPRKIELADRDPKLYSMDPWITTKTLPDYLLSKITNGYILLVIHIGTSSQTIKVSID
DTPVQVLQSFFTKIANKRALLGIPEEVNESDFVLRVCGREEYIYGNYAIKDFHWIRQSLK
SGEEIHLVLEPPPNPEQDGVQKEDWSQVDDCTGVAGTHEQLTIDEKDHEKVFTISLWDCN
RKFRVKILGIDIPVLPRNSELIVFVEASVFHGQQQLAYERTSPKPFTEEVLWNTWLEFNI
KIKDLPKGARLNLQVSCSKAQTQTSRDSAVHDCKTKSRLLYYVNLLVIDHRSLLRQGEFI
LHMWKMPEKSAEDSSVNADKLTSATNPDKTSSMAIAVLLDKYCYPVALPKSRDSRDSSDM
EGERGKREMPNHLRKQFEQIVATDPLHPLSSEDKELLWHFRQDCMRHPSAYPKFLGSVKW
GKQEDVMATHQLLERSTTWDRSPLDVGLAMQLLDCHFSDAKVRTMAVRKLETLGDDDVLR
YLLQLVQAVKFEPYHDSALAQFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILE
AFLRGCGEVMLQDFSKQVEITEALQKITREIKAMSAEKYDVSPQVVLQLRQKLDSLQSSG
LPESFKVPFDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDL
RQDMLILQILLIMESIWETESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGN
TGAFKDEILNQWLRDKCVSEEKYQQAVDRFVFSCGGYCVATYVLGIGDRHNDNIMITESG
NLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTTGKKSSPNFLNILFKNNAYVN
VG
>A0A8B9J9G4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLISVKQQLFVNTPYKYPLF
HLLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGF
AIGMPICEFELVKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPSVESSPQLPQ
HIYCKLDKGRLIVTIWVVVSPSNAKQKYTLKIAHDCLPEQLIAEAIRKKTRSMHLSAQQL
RLCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCITVGKLPHLMLVSKDSLYSQLPA
SGFVAPSYSRRTPQPSPCPGGSDPSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVR
TGIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLTDLPRSARLCLSICSVKGRKGAKE
EHCPLAWGNVNLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEF
SSFNQMVVFPDEQQIEEHANWIVSRELGYNYSLSLSNRLACDSTISQAELEQLRSLCSRD
PLYELSEQEKDFLWRHRHYCVNIPESLPKLLLAVKWNSRDEVSQMYCLLRDWPLMQPESA
LELLDCNFPDPMVREFALRCLIQGLTDDKISQYLLQLVQVLKYEMYLDNPLARFLIKKAL
TNQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDT
LKHEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRP
LWLNWENPDIMSELLFTNNEVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGC
LSIGDCVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKEKNKGEGYDKAIDLFT
RSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQ
DFLIVISKGMQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDD
IAYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A8B9J9S8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLISVKQQLFAEARKYPLYH
LLQVNTPYINTPLPPVTEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIG
FAIGMPICEFELVKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPSVESSPQLP
QHIYCKLDKGRLIVTIWVVVSPSNAKQKYTLKIAHDCLPEQLIAEAIRKKTRSMHLSAQQ
LRLCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCITVGKLPHLMLVSKDSLYSQLP
ASGFVAPSYSRRTPQPSPCPGGSDPSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYV
RTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLTDLPRSARLCLSICSVKGRKGAK
EEHCPLAWGNVNLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVAGSNPNKETPCVELE
FSSFNQMVVFPDEQQIEEHANWIVSRELGYNYSLSLSNRLACDSTISQAELEQLRSLCSR
DPLYELSEQEKDFLWRHRHYCVNIPESLPKLLLAVKWNSRDEVSQMYCLLRDWPLMQPES
ALELLDCNFPDPMVREFALRCLIQGLTDDKISQYLLQLVQVLKYEMYLDNPLARFLIKKA
LTNQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTD
TLKHEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKR
PLWLNWENPDIMSELLFTNNEVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYG
CLSIGDCVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKEKNKGEGYDKAIDLF
TRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLT
QDFLIVISKGMQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFD
DIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A8B9H3X2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astyanax mexicanus|TrEMBL
MEQHISDDEPPAVPREENNKRRRRKMKAFTSATSVPVDHLVMEFVLPTTNKTTKNPDTVQ
LEVLGNWTVEQVKAQLWLRAVATNLCPEFYQKFSPDHTILLYQKKGSWCEIYDKHQVFQT
LDCIRYWKALKKEIGKIHLVLRPQSSEESVQYQKFLNHLIGYDVTDVSNVHDDELEFTRR
KLLTPRKIELADRDPKLYSMDPWITTKTLPDYLLSKITNGYILLVIHIGTSSQTIKVSID
DTPVQVLQSFFTKIANKRALLGIPEEVNESDFVLRVCGREEYIYGNYAIKDFHWIRQSLK
SGEEIHLVLEPPPNPEQDGVQKEDWSQVDDCTGVAGTHEQLTIDEKDHEKVFTISLWDCN
RKFRVKILGIDIPVLPRNSELIVFVEASVFHGQQQLAYERTSPKPFTEEVLWNTWLEFNI
KIKDLPKGARLNLQVSCSKAQTQTSRDSAVHDCKTKSRLLYYVNLLVIDHRSLLRQGEFI
LHMWKMPEKSAEDSSVNADKLTSATNPDKTSSMAIAVLLDKYCYPVALPKSRDSRDSSDM
EGERGKREMPNHLRKQFEQIVATDPLHPLSSEDKELLWHFRQDCMRHPSAYPKFLGSVKW
GKQEDVMATHQLLERSTTWDRSPLDVGLAMQLLDCHFSDAKVRTMAVRKLETLGDDDVLR
YLLQLVQAVKFEPYHDSALAQFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILE
AFLRGCGEVMLQDFSKQVEITEALQKITREIKAMSAEKYDVSPQVVLQLRQKLDSLQSSG
LPESFKVPFDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDL
RQDMLILQILLIMESIWETESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGN
TGAFKDEILNQWLRDKCVSEEKYQQAVDRFVFSCGGYCVATYVLGIGDRHNDNIMITESG
NLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTTGKKSSPNFLKFQDVCVRAYL
ALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGCSEDEAQKHFLDQIEICRDK
GWTVQFNWFLHLVLGIKQGVEKRSA
>A0A6J2ACC5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Acinonyx jubatus|TrEMBL
MPPFHCLARPIRVDIHKVPAIALQVVQGMELDNYEQPVVLREDNRRRRRRMKPRSTTASL
SSMELIPIEFVLPTSQRNSKTPETALLHVAGHGNVEQMKAQVWLRALETSVATDFYRRLG
PDHFLLLYQKKGQWYEIYDKYQVVQTLDCLRYWQVLHRSPGQIHVVQRRAPSDETLAFQR
QLTALIGYDVTDVSNVHDNELEFTRRRLVTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLL
KKITNNCIFIVIHRSTTSQTIKVSADDTPGAILQSFFTKMAKKKSLMDIPESQSEQDFVL
RVCGRDEYLVGETPIKNFQWVRQCLKNGEEIHLVLDTPPDPALDEVRKEEWPLVDDCTGV
TGYHEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNADLTVFVEANIQHGQQ
VLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPRGALLNLQIYCSKAPVLAGKTSAETPSS
ESKGKTQLLYYVNLLLIDHRFLLRHGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKEN
SMSISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDK
ELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLD
CNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIG
HFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTDQVQVIEMLQKVTLDIKSL
SAEKYDVSSQVISQLKQKLENLQNSNLPKSFRVPYDPGLKAGALVIEKCKVMASKKKPLW
LEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCIST
GDKIENQTREIAAWLKSPLPSCQQRPSHSSSGSGARPQCPSASVHLLIGMIEIVKEATTI
AKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRH
NDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQK
FQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYF
LDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A671T2U9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPAKTDQLDLWAESGLDGDVQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSCGEWLRSCYSTQLGTGSLE
NLIDKHEGDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDYVLRVSGRFEFLF
EDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLARKTSNPPLPLPPK
KRPPTVSTLSVFPALQLIKGIQVRAGLFHGTELLCKTAVSSESSSRSEHVWNKTLEFDIA
VCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIPWVNTMVFDYRGQLKTGDIILH
CWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVFPAFDKGRGGKKFYIE
LKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLSPRDALELLDFNYPDQYVREFAVICLRDMSDDELLQYLLQLVQVLRYEPYYDCALS
RFLLERAQSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALN
KLKAVSELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLQSPLNPNILLAGVHVER
CKYMDSKMKPLWIVYNNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLR
IVPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALD
KAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRER
VPFILTHDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPEL
TSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A671L7Q3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLFLPFWLCSKWHKTFSTGHHEFDSQKNHEVNE
FRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQSGKSHSGKKILVNVKFEGS
EETFVLQQDPQDLPMFLKRNALRKKSTVFRPAKQEKPEDYTLQVNGRWEFIYGKYPLCQF
KYIFTCLHGGITPHLTMVHHSVIIKYPAQETFLVMSYYVVLLNIFVETLVVQAGLFHGSE
LLCKVVTSNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKR
ADCPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLI
RFPNIRPHPLYYPPIEKLNELGMNCEKVVATKEEHLKLREIVDNKNYTEFFEDEKELLWK
LRKEVRQRYPESLPKLLLITKWNKHEDVAQMVCLLRKWQELPAIHALELLDYSFPDPHVR
SFTIRCLRNLRNDELFQYLLQLVQVLKYESYLDCDLTCFLLERALSNKKIGHFLFWHLRS
EMHVPSVSLRFGLILEAYCRGSIFLIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTE
DMKVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKDKYDHVGII
FKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGD
RHSDNIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKF
ERFRECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALK
NFKVKFNEALRESWKTKVNWMMHSFAKDNR
>A0A7K9XVZ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Psophia crepitans|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAARRQQLSWAAWMEYNFPLQLEPKAEGLGT
GPLHTTTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYRFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQANCIASPPKMA
AKPPPLPKKKPNYASLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSIAL
HPVYYPSFEQLLELGRNGEQPRTAPEDPEEKLQLKEILERRAQSELYEHEKDLMWKLRYD
IRDQYPQALARLLLITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKSLNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A672TFJ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYILDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREGLLVTQQCFSLL
>A0A3P8V5V7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cynoglossus semilaevis|TrEMBL
MPPGKYGMQEEWEKEGVQEIVMDFLLPTGIFLKFPVSRNDTIKNIKKMVWRNARSEALFS
ALGDPDAYVFTCINQTAEREELEEESRRISDVQPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNHEVNEFRLKMRTFCEDKALEQQRLPWQQWMEYSFPTDLEPCGSPPQK
SKNIKKIFIIVKFEACDESFMLQQNPQDNPGALIRSALKKKATVFRSMRQEPEDYTLQVN
GRWEFIYGKHPLCQFKYIFSCLTNGQNPHLIMVHRSTISKYQEEQGRMCSQVFKSHSSSR
PPPLPLKKCTSSLWSINEPFCVQLLQGIRVNADEGMKLVVQAGLFHGSELLCKIVTSSEV
TVCSEPLWDQKLNFDINVADLPRMSRLCFALYAVIEKNKKPRGTKKKNKKAISEVETNGD
IAHVTKEEHMKLKEIMDNKNYTEFFEDEKELLWKLRAEVRNHYPESLSKLLQITKWNKRE
DVVQMVSLLRNWPDLPAIQALELLDYSFPEPAVRYFTIRCLRMLSDDELLQYLIQLVQVL
KYESYLDCDLTTFLLERALSNKRIGHFLFWHLKSEMHVPSVTLRFGLILEAYCRGNIHHI
KLLSKQNEALGKMKALSDFVKSGSQKLTAEDLKMCIRQESYLEALSDILSPLNPSIILTE
ICADKCRFMDSKMKPLWLMYKNNLSQGDMVGIIFKNGDDLRQDMLTLQMIQLMETLWKKE
GLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNP
EDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLG
INRERVPFILTYDFVHVIQEGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAA
GLPELTSFKDIQYLKDSLALGKTEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A8C6AJQ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodon monoceros|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C4CBE9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
TVLENVDVLRRRRKMKAFTSSSAVGSEQLTVEFVLPTTSKTSNAPDTLNLEVAGNCTVEQ
VKAQVWLKAVADQISPQFYEKYSPDHCILCYQKKGSWCEIYDRHQVFQTLDCIRYWKVLK
KDVGKIHMYRRPQPSEESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPRKIELS
DRDARLYSMDPWVTTKPLPEYLTSRISNGHVLLVIHRNTSSQTIKVSIDDTPFQVLQSFF
TKIANKKALLDIPENVTESDYVLRVCGREDYVFGNYAIKDFHWVRQCLKNGEEIHLVLES
APNPDQDVVEKEDWSQVDDCTGVAGTHEQLTIDEKDHDKVFTISMWDCNRKFRVKVLGID
IPSLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNAWLEFNIKIRDLPKGSRL
SLQVSCGKAQTQTSKVSNLDGSFDGRCKSRLLYYVNLLLVDHRSLLRQGEFVLHMWKMPD
KSEDNSSVNADKLTSATNPDKTSSMAVVIMLDKYCYPVALPKSPESRDSEAEGDRGQREM
PNHLRKQFQQIVSTDPLHPLSPEDKELLWHFKQECLRNPKAYPKFLGSVKWGKQEAVMTT
HQLLERSTTWDRSQLDVGLAMQLLDCHFSDTNVRSMAVRKLETLDDDDVLRYLLQLVQAV
KFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGNA
MLQDFKKQVEITEALQNVTREIKAISVEKYDVSAQVVLQLRQKLESLQSSGLPESFRVPY
DPGLRAGGLVIEQCKVMASKKKPLWLQFKPADPTTLSSDTIGIIFKDGDDLRQDMLILQI
LLIMESIWEAESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSIVGNTGAFKDEIL
SQWLRDKCVSEDKFQQTVERFVYSCSGYCVATYVLGIGDRHNDNIMVTEAGNLFHIDFGH
ILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFLKFQEVCVKAYLALRQHTNLL
IILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEDDAQRHFLDQIEICRDKGWTVQFNWF
LHLVLGIKQGVEKRSA
>A0A836AQN0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ovis aries|TrEMBL
MPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISCIKQMLWKQVTNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKHTYPPELEPSIPE
NLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDEVSPYDY
VLQVSGRVEYVFGDHSLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMVAIEAAINR
NSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TVVSSEISGKNDHIWNEPLEFDINTCDLPRMTRLCFAVYAVLDKVKTKKSTKTMNPSKYQ
TIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPHALPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALA
NRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLKTLNSLI
KLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPL
WLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGD
RSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCA
GYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3P9K8U0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETCYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDFEVQDFRRNILNVCKDAVELRDANGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYSQLPTD
SFVMPSYCRRISTATSYMNGEAAPKSLWTISGGLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLNYDMYILDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYNHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEHF
SSPVKYPDMNAVEEHANWTISRELGFNYNTSGQSNRVARDHALTDSDSEQLKQLSNRDPL
SEITEQEKDFLWRYRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKFLADDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNRGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKGEQVSRHFTGNQNLRSFETSPHQLKRLFHVAGSIGLLYETDERCSPWRVD
HQDGLDIPHN
>A0A3P9K527|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MDRQSIQVSDEEPEVPREECRRRRRKKAITSSSCVSMDQITIEFVMPSAARGGSGPDILT
LDVAGNWTVEQVKAQVWMKAVTLNLCPDFYQRLSPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIPYWRALKKGVGRIQMATRPQLSEESLQYQRYLNCLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVNNGHILVVIHIGMVSQTIKVSIN
DTPSQVLASFFAKTANKRVLLGIPDDVCEADFVLRVCGREEFLFGEKPLQNFNWIRQCLK
NGEEIHLLLEKPPDPELDVVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPTLPKVPELVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVICGKPTQTPASKGSSHYDNSAGTGSVEGKTKNRLLFYVNLLLVDH
RSLLRQGEFILHMWKMPEKSDESSSSINADKLTSATNPDKSSSMAVAILLDKYCYPVVLP
KSRDVGKDSGAGEEMEGGERGQREMPNHLKKQFEAIVSTDPLHPLSPEDKELLWHFRQEC
MRDPRAYPKLLGSVKWGKQEDVLATHRLLERSNAWDTSGLDVGLAMQLLDCHYSDSHVRS
MAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGESMLQDFRKQVEMTMALQKVTRDIKAIAADKYDISAQ
VVFQLRQKLETLQSSGLPETFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTT
LSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETECLDLCLLPYGCISTGNKIGMIEIV
KDATTIANIQQRVVGSTGAFKDEILHQWLRDKCVSEDKFQQAVERFLLSCGGYCVATYVL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKS
SPHFLKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEE
EAQRHLLDQIEICREKGWMVQVNWFVHLVLGIKQGVEKRST
>A0A7K7UJV2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ibidorhyncha struthersii|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQNPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
TKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSIVS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C4X608|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Erpetoichthys calabaricus|TrEMBL
MPPAMTDILDSWGVDSNLANDVTLKADFLLPNGIYIQMEVPRESTILNIKSILWKQVQGY
PMFSILEPMEEYMFECVNQTAVHEELEDESRRLCDIRLFLPVFKLVTRNCGRTEKLLESK
IGVLIGKGLQELDALEDPEVKDFRSKMKRISEEKMQKVQQFTCLEWAQKNFSASQEPHKP
EVLNERLVGNDMVVNIYSEQYQGIISLEVSPEILPSNLAEEVLGRLLHHCKEEEQADASK
YILQIAGRLEFLLDNQPLINFKYIRNCIINQETPRFTLTSCGIVQEIYDKEVSYIPNIIN
RKSSIAPVPLPPKKRGVSHISPTTCVWNVTENFKIILLKGSKVNAEESVKVHVRAGLFHG
TELLCKPLVSNETSGKSDHIWDKTLEFDINVCDLPRMTRLCFAVYAVMDKVKKQRPTKTT
HVQKYQTIRKAGKVHYPIAWVNTMVFDFRGHLKTGDIVLRTWSSFPDELEEMLNPIGTVQ
TNPYNENPTALHIRFVEYSNCPVVYPPFDKILEKAAMIARSSDSMTMSSRGGKKFYIELK
EIMERDPLSQLCENEKDLIWKLRHDCRENFPQSLPKLLLSVKWNKHEDVSQLQSILQIWP
KLSPRDALELLDFNYPDQYVREFAINCLNVMSDEELSQYLLQLVQVLRYEPYYDCALTKF
LLERAQANRRIGHFLFWHLRSEIHMPTVCIQFALILEAYCRCNIPHIEVLRRQVEALNKL
KVVNELIKFGTIKNAKSKAKEAMLSCLKQTGFTESLSSLPSPLNPNIILSGFNVDKCRFM
DSKMKPLWIVYEDKHFGNDCLGIIFKNGDDLRQDMLTLQILRLMDMLWKEADLDLRVVPY
GCLATGDKSGLIEVVPASETIANIQLTNSNVAATAAFNKDALLNWLKEKNSGDALDRAIE
EFTLSCAGYCVATYVLGIGDRHNDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFI
LTYDFIHVIQQGKTGNTEKFGRFRQYCEDAYLILRKNGNLIITLFALMLTAGLPELTSVK
DIQYLKDTLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDKRS
>A0A8C4SJ07|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Erpetoichthys calabaricus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLYH
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVDLRDANGPHSRALYVYPPNVESCPELPKH
ISSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKESLYSQLPTD
NFTMPSYARRISTATPYMNGEASSKSLWSVTDTLKIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMFIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVSGKMALNLWSVPHGLEDLLNPIGVTGSNPNKETPCLEIEFDNF
SSLLKFPDMSAIEEHATWTMSRDLGINYFQSGLSNRLVRDNDLTENDLEQFRLLCNRDPL
SEITEQEKDFLWRNRDYCVNIPEILPKMLLAVKWNSRDEVAQMYCLLKDWPPIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGSLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKHGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSYTMMHIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHTMT
>A0A6J0SSM5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pogona vitticeps|TrEMBL
MTLGIYCPVEFWSKETNQSIPVDFLLPTGIFLTLPISCHATLRTIKKVLWQHAQYEPLFH
MLSDPESYVFTCINQTAERQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQVSLL
IGKGLHEFDSLGDPEVNDFRTQMQQFCEERAARRQQLSWKAWMEYSFPVQLEPVANGLGK
KSPLQIPNKNLFVNVKFESGGESFTFQISPKEVPATLMSYAIKKQATIFRHQKVNSPEDY
ALQVNGKYEYLYGNYPLYQFQYVRHCLHRGLLPHLTMVHSSSILALWEEQTNGITSPPKA
GTRPPPVPKKKPTSVSLWSLEQPYYIDLIQGSKVNADERMKLVVQAGLYHGHEMLCKMVS
SPEVSVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKTKKARSTKKKSKKADCPIA
WVNVMLFDFQDQLKAGECSLPMWSSFPDDRGELLNPMGTVQTNPNTESAAALVIRFPSIS
SYPVYYPSFEQILEQGRNEPSPSYGLEDPEEMQQLREILERRSHTELYEHEKDLMWKMRQ
QIRDHYPGALAKLLVVTKWNKHEDVAQMIHLLQSWPELPVLSALELLDFSFPDRYVGSFT
VNSLKKLTDAELFQYLLQLVQVLKYESYFDCELTRFLLDRALSNRKIGHFLFWHLRSEMH
VPSVSIKFGLILEAYCRGSIHHMKALMKQIEALNKMKALSDIIKASAQKNTKPQTKEFMH
TCMRQETYLEALSNLQSPLNPSVILAKVSVDLCTFMDSKMKPLWIVFNNEEMGGSTVGVI
FKNGDDLRQDMLTLQMIQLMDILWKKEGLDLRMTPYGCLSTGDKTGLIEVVMNSDTIANI
QLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFR
GYCETAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEARKQFQL
KFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C8XHR2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera leo|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINICDLPRMARLCFAIYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A2I0MBJ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Columba livia|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVELRDANAPHSRALYVCPPNVESSSELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYNQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSCAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLRDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXHSKDPCVGQNRAGSS
>A0A7K8EZB6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Struthidea cinerea|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNIKFQSGGESFTFQVSPWEFPITLMSYAVKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2Y9K9I1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Enhydra lutris kenyoni|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRRQLGWEAWLQYSFPLQLEPSARGWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEELQLREILERRGSGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCLRQ
ETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A7L1ADU8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gymnorhina tibicen|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSARTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A2U9C1Y3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MILTLECLREATLITIKHELFKEARKYPLHHLLQEETSYIFVSVTQEAEREEFYDETKRL
CDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPEVQDFRRNILNVCKD
SVELRDASGPHSRALYVYPPNIESTPDLPKHIYSKLDKGQIIVVIWVIVSPNNDKQKYTL
KINHDCVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQGKYILKVCGCDEYLLEKYAISQ
YKYIRSCIMLGRMPNLMLMAKDSLYTQLPTDNFVMPSYSRRISTATSYMNGEGAAKSLWA
INGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQMCDNVNTQRVPCSNPRWNEWLTY
DMYIPDVPCAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTHVLVANKMALNLWPVP
HGLEDLLNPIGVTGSNPNKETPCLELEFDHFSSQVKYPEMNAVEDHANWIISRELGFNYN
LSGQSNRVARDHALTDSDTEQLRQLSNRDPLSEITEQEKDFLWRHRHYCMNIPEILPKIL
LAVKWNSRDEVAQMYCLLKEWPSIRPEQAMELLDCNYPDPVVRHFAVRCLDKYLTDDKLS
QYLIQLVQVLKYEQYLDNPLARFLLKKALTNQKIGHFFFWHLKSEMHNKTVSQRFGLLLE
AYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMRFLVDQMKRPDYMDALQ
NYTSPLNPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQ
DMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRSSHTIMQIQCKGGLKGA
LQFNSNTLHQWLKDKNKGEMYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQL
FHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECAKTKEFERFQEMCYKAYL
AIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKSEQEALDYFMKQMNDAHHG
GWTTKMDWIFHTIRQHALN
>A0A091TB75|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phaethon lepturus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPVTKGLGT
GPLHNPAKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPPFEQGLSELRLSPVYALSCDSYEQKLQLKEILERRSHTELYEHEKDLVWKMRYD
VRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILSEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGCAGYCVATYVLGIGDRHSDNIMIQETGQLFHID
FGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHG
LLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKV
NWLAHNVSKDNR
>A0A8D3B796|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPGKYGMQEEWEKEGVQEIMMDFLLPTGILLKFPVSRNDTIKSIKKMVWKNARSEALFC
GLGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRAEKLINTQISLL
IGKGLHEFEAQKNHEVNEFRTKMCIFCEEKAQERQMLPWQQWMEYNFPCDLEPCCTPPHS
GSLKSKNTKKFFINVKFEACDESFMLQQDPQDHPVALMRSALKKKANVFRSVRQEPEDYT
LQVNGRWEYIYGKHPMCQFKYIFSCLRNGQNPHLTMVHHSTISKFQEEQGQMCSQEYKSR
SLSRPPPLPLKKLNTSSLWSITEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFANI
RPHPLYYPPLDKVLVPKRLCWYMKLKEIMDNKNYTEFFEDEKELLWHLRTEVRDRYPENL
SKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAIRSFTIRCLRKLSDD
ELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVTLRFGL
ILEAYCRGNIHHIKLLTKQNEALSKMKTLSDFVKSGSQKLTAEDLKLCIRQESYLEALSD
LLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNNWAPEDMVGIIFKKGDDLRQDMLTL
QMIQLMETLWKREGLDLRMIPYGCLSTGNKMGLIEVVENSDTIANIQRNNSNTSLTQRLD
KLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGIN
RERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGL
PELTSFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A7K8JZX4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lophotis ruficrista|TrEMBL
MPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLRLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPSLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVHDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPTAKSLGT
GSLPTPSKNIFVNIKFQSGGESFTFHISPKEFPITLMSYAIKKQATVFRHETLDNPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQSRTALEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
VRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFNFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEHAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRD
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A673HRS6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
SISLLWKEAQTYPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITR
NCGRAERILDSKIGVLIGKGLHELDALQDQQVKDFRSKMKRVSEEKMQRMQLMSCGEWLR
SCYSTQLGTGCPYNEINYHLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDYVLRVS
GRFEFLFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLARKTSNP
PLPLPPKKRPPTVSTLSVFPAHQLIKGVLSFVHLAVRAGLFHGTELLCKTAVSSESSSRS
EHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIPWVNTMVFD
YRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVFPS
IMQRILVKNRPQRPEKLSELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLL
SVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVICLRDMSDDELLQY
LLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAY
CRGCIPHIEVLKKQVEALNKLKAVSELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLS
DLQSPLNPNILLAGVHVERCKYMDSKMKPLWIVYNNKLLGGDTVGIIFKNGDDLRQDMLT
LQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQKTSSNMAAAAAF
NKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHI
DFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKN
GNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTK
VNWMAHIVAHPS
>A0A673HQ78|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
IVLSAMPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKE
AQTYPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERI
LDSKIGVLIGKGLHELDALQDQQVKDFRSKMKRVSEEKMQRMQLMSCGEWLRSCYSTQLG
TGSLENLIDKHEGVIKITMHYDQSQVCSVILICNIGTRSDYVLRVSGRFEFLFEDHPLNQ
CKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLARKTSNPPLPLPPKKRPPTVS
TLSVFPAHQLIKGVLSFVHLVRAGLFHGTELLCKTAVSSESSSRSEHVWNKTLEFDIAVC
DLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHYPIAWVNTMVFDYRGQL
KTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVFPAFDKIL
EKAAEIAGASDSMTMGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQS
LPKLLLSVKWTFQNSLCCAPSRLYTCKEAGISVSVHFALILEAYCRGCIPHIEVLKKQVE
ALNKLKAVSELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLQSPLNPNILLAGVH
VERCKYMDSKMKPLWIVYNNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRIVPYGCLATGDRSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGD
ALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A673HP58|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
SISLLWKEAQTYPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITR
NCGRAERILDSKIGVLIGKGLHELDALQDQQVKDFRSKMKRVSEEKMQRMQLMSCGEWLR
SCYSTQLGTGSLENLIDKHEGDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSD
YVLRVSGRFEFLFEDHPLNQCKVRYVVHSLFRINLVKGNKVNAEDTAKIQVRAGLFHGTE
LLCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHL
NKYQTIPWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELH
ISFPEYSTQPVVFPAFDKVLDDVFSWRPFMLWSRRVMTSQGRGGKKFYIELKEIMERDPL
SQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDAL
ELLDFNYPDQYVREFAVICLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSS
RKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVSELIK
LGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLQSPLNPNILLAGVHVERCKYMDSKMKP
LWIVYNNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATG
DRSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSC
AGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFI
HVIQQGKTGNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A7K6TYU6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aegotheles bennettii|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKIPEIMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVIQTLD
CILYWRVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKIINNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPSSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISVVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A0A0A6V1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Charadrius vociferus|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRLSEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A5N4EIA6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Camelus dromedarius|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPSNSKDLEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVP
HGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYS
HAGLSNRLARDNELRENDKEQLRAICTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLL
LSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRSFAVRCLEKYLTDDKLS
QYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLE
SYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQ
GFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQ
DMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGA
LQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQL
FHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFER
>A0A6F9AKS2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coregonus sp. 'balchen'|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILILECLREATLITIKHELFKEARKYPLHH
LLQEENSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKCPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGESSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMTTVEGHANWTISRELGFNYCQSGQSNRVARDHALTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQMHNKTVSQRFGLLLESYCRACGM
YLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNP
AHQLGNIRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQII
RIMENIWQNQGLDLRMLPYGCMSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTL
HQWLKDKNKGEMYDLAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHF
LDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANL
FINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDW
IFHTIRQHALN
>A0A3Q3E631|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Labrus bergylta|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQDLPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKFPISQYKYIRSCIMLSRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDIEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLSRFLLKKALTN
QKIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNELIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A3Q3F2V9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Labrus bergylta|TrEMBL
MPPAMTDLLDIWAGHSPLAGHALDTITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPMFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAMNDQEVKDFRCKMFRLSEERMQRVQMMTCMEWLQACFSPQLEPM
AGTAITDGLNERQVDLKVIIHFDQSQDSASVMVPSSCTPTELMEQAVRKWLTTHGPEEEA
WQGQYVLRVSHCLEFLCGDDPLSQYKYIRTCLQAKEPPHLTLVHTSTVKAMFDKEISAIG
AVVSRKSSNPPLPLPPKRRVQTCVWGVSSPFKIVLVTGSKVNAEETAKVQVRAGLFHGTE
LLCKPAVSSESNGRSDHTWKDSTLEFDISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNAH
INKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKIGHIILHCWSSFPDELEEMLNPIGTIQT
NPYTENATALHIHFPEYSSHPIIFPPSIRSDSSQSGRGGKKFHIELKEIMERDPLSQLCE
NEKDLIWTLRYDCWENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLCPRDALELLDF
NYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLKRAQGNRKIGH
FLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIK
NARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNILLVEKCRYMDSKMKPLWIVY
NNKLLGGDSLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRAGL
IEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSSDTLERVIEEFTLSCAGYCV
ATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQ
GKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLAL
GKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A4D9DVA5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Platysternon megacephalum|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVCPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASVKSLWVINSTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMTVIEEHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C8CC43|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPAMTNLMDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQACFSPQLEPGGG
ATPVTDVTQHAYHFENDTASLKVWPSTSPSELMEQALRKWLTTHGPEEEGRQAEQYVLRV
SDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSTVQAMFEKEISAIGAVVNRKSSN
PPLPLPPKRRGPSQVNTCVWEVSTHFKIVLIKGSKVNAEETAKIQVRAGLFHGTELLCKP
AVSSESSGRSEHVWNRTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKSTKNAHINKYQT
IRKSGKVHYPVAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPIGTIQTNPYTEN
TTALHIHLPDYNPHTILFPPFDKILEKAAEIAGSSDCLPMGRGGKKFHIELKEIMERDPL
SQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDAL
ELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLNRAQCN
RNIGHFLFWHLRSEMHMPAVAVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIK
LGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMDS
KMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGC
LATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
HDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A8C8LR62|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MEQQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQALQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDC
HRKFRFKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFN
IRIRDLPKGARLSLQVSCGKAQTQISKGTSSYQDNGGSPVGGGSGNHDCNKTKSRLLYYV
NLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYC
YPVALPKSREGKEAGGEGREAEGGERGQREMPNHLRKQFEAIVETDPLHPLSQEDKELLW
HFREECMRHPRAYPKLLGSVRWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYS
DAHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLF
WFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEK
YDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFK
RADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKI
GMIEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYC
VATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMG
TSGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALT
VGRTEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A337SKK8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Felis catus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLALMACALRKKATVFRQPLLERPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSAPDEKGELLNPAGTVRSNPNTESAAALVICLPEVSP
YPVYYPALDKQLQLREILERRGSGELYEHEKDLVWKMRHEVQERFPEALARLLLVTKWNK
HEDVAQMLYLLCSWPDLPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQ
VLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTH
HMKVLMRQGEALSKLKALNDFVKVSSQKTTRPQTKELMHLCMRQETYLEALSNLQSPLDP
STLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDSSVGIIFKNGDDLRQDMLTLQMIQLM
DVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLN
WLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLG
NFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGPLFLHL
FALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHN
VSKDNRQ
>A0A2Y9H8I3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neomonachus schauinslandi|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A671WM27|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MENQGNDEEPRVVREETRRRRRKKAITSSSCSSMDQITVEFVLPTTARGGNSPDTVLLDV
AGNWTVEQVKAQVWLKAVTLNLCHDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDC
IRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLL
TPRRIELSERDPKLYSMDPWVTRKLLPDHLLSKVSNNHILVVIHIGTVSQTIKVSIDDPP
AQVLASFFAKTANKRVLLGIPDDMCEEDFVLRVCGREEYLYGEKPLHNFNWIRQCLKNGE
EIHLVLESPPDPELDQVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKF
RVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLEFNIKIK
DLPKGARLNLQVVCGKQPQTPNSKTGKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMP
EKSEESSSSINADKLTSATNPDKASAMAIAILLDKYCYPVVLPKSRDVGRDVGAGGEEAE
GGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRW
GKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLR
YLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLE
AYLRGCGEDMLQDFRKQVEMTEALQKVTREVKAMSADKYDITAQVVFQLRQKLENLQSSG
LPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDL
RQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGS
TGAFKDEILYQWLRDKCVSEDKFQQAVEKFLYSCGGYCVATYVLGIGDRHNDNIMITESG
NLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYL
ALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREK
GWMVQINWFVHLVLGIKQGVEKRST
>A0A671UL24|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMLKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSTQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPARSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYTDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFSQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDNSVSASDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGSLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEGYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A7K8BRG9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhagologus leucostigma|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLNWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVRFQSGGESFTFQISPWEFPITLMSYAVKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWRQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A1A8L992|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius pienaari|TrEMBL
MPPGKYGMQEEWEKEGDQNILMDFLLPTGIFLKFPVPRNDTIKNIKKMVWRNAKTEALYF
GLGDPEGYVFTCINDTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNSHISSL
IGKGLHEFEAQKNHEVDEFRSKMRTFCEEKALERHNLPWQQWMEYSFPCDLEPCCSPPVH
GGTKSKHTKKLFINVKFEACDESFMLQQDPLDIPVALMKSALKKRATVFRSVRQEPEDYT
LQVSGRWEFIYGNHPLGQFKYIFSCLRNGQNPQLIMVHHSTISKYQEEQGQLCSQVGKIR
SQSRPPPLPMKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQKLDFDINVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKRADCPI
AWVNTMVFDYKDQLKTGEFILSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPPLDKMIVMERNGDAVFATKVERMRLKEIMDNKNSTEFFEDEKELLWKLRTEV
RDCYPESLSKLLLITKWSKREDVVQMVSLLRNWPDLPAIQALELLDYSFPDPAVRSFTIR
CLRKLSDNELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVA
SVSLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDIVKSGCQKMTVEDLKLCIRQE
SYMEALSNLMSPLNPSIILVELCADKCRFMDSKMKPLWMMYKNPSEHADMVGIIFKNGDD
LRQDMLTLQMIHLMEDLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKHSDTIANIQRNNSN
SAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEWA
YKILCKNGTLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEDEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A6Q2XMD0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLTSIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFEQVKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESAPELPQH
IYCKLDKGRLIVTIWVIVSPSNSKQKYTLKISHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYVRGCITMGRLPHLMLVSKDSLYSQLPGS
GFVAPSYSRRTPQPSPCPGGGDPSTPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDTLVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQVVLFPDEQQIEEHANWTISRELGYNYCLGLSSRLACDSSVSVADGEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEWSQMYCLLRDWPLMQPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWDNPDIMSELLFTNNEVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A852KRL4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Urocolius indicus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFVLPTSNKHTKVPEMLLLE
IAGNCTVEQMKAQVWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPTLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSLESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIESLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A803TNS4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anolis carolinensis|TrEMBL
MLPGIYCPVEFWSKEANQSIQVDFLLPTGIYLTLSVSCNATLGTIKQLVWHHAQCEPFFH
MLSDPESYVFTCINQTAERQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLISSQISLL
IGKGLHEFDSLGDLEVDDFRVKMQHFCEERAARRQQLSWKAWMEYSFPVQLEPLANGLGG
RSLLQFPNKNIFVNVKFESGGESFTFQISPKEYPATLMSYAIKKQATVFRHQKINSPEDY
ALQINGKYEYLYGNHPLYQFQYIRDCLCRGLLPHLTMVHASSISALWEEQTNGISYPIKA
ASKAPPVPKKKPMSVSLWSLEQPYSIELVQGSKVNADERMKLVVQAGLYHGHEMLCKMVS
SSEVSVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIA
WVNVMLFDFRDQLKTGECCLPMWSSFPDEKGELLNPMGTVQTNPNTESAASLVIRFPTIS
SNPLYYPTFEQVRSDSITSLWVAVSFPEQQLKEILERRSHTDLYEHEKDLVWKMRHQIRD
QFPHALAKLLVVTKWNKHEDVAQMIYLLQSWPELPVLNALELLDFSFPDRYVGAFTVNSL
KKLTDADLFQYLLQLVQVLKYESYLDCELTKFLLGRALSNRKIGHFLFWHLSSQKNAKPQ
TKEFMHTCMRQETYLEALSNLQSPLNPSVILAKVSVELCTFMDSKMKPLWIVFNNEDAGG
GHVGVIFKNGDDLRQDMLTLQMIQLMDILWKKEGLDLRMTPYGCLSTGDKTGLIEVVMDS
DTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGI
GDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSE
KFERFREYCERAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEA
RRHFQLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6Q2WUS0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MPPRPSSGELWGMHLMPPTIQVDCLLPNGMILTLECTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPVD
TFAMPSYARRISTATPYMNGETAAKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANWNISRELGFNYSHSGLSNRVARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVSIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDSLCQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQ
ECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALD
KTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A803U116|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anolis carolinensis|TrEMBL
MLPGIYCPVEFWSKEANQSIQVDFLLPTGIYLTLSVSCNATLGTIKQLVWHHAQCEPFFH
MLSDPESYVFTCINQTAERQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLISSQISLL
IGKGLHEFDSLGDLEVDDFRVKMQHFCEERAARRQQLSWKAWMEYSFPVQLEPLANGLGG
RSLLQFPNKNIFVNVKFESGGESFTFQISPKEYPATLMSYAIKKQATVFRHQKINSPEDY
ALQINGKYEYLYGNHPLYQFQVCIPLLASAPPVPKKKPMSVSLWSLEQPYSIELVQGSKV
NADERMKLVVQAGLYHGHEMLCKMVSSSEVSVCSEPVWGQRLEFEINVCDLPRMARLCLA
LYAVVEKAKKARSTKKKSKKADCPIAWVNVMLFDFRDQLKTGECCLPMWSSFPDEKGELL
NPMGTVQTNPNTESAASLVIRFPTISSNPLYYPTFEQVRSDSITSLWVAVSFPEAFSPDI
SPTSMAGILRGCEVCWKLSKWGLHTCGGRKNCLFEASVNVDPEEQQLKEILERRSHTDLY
EHEKDLVWKMRHQIRDQFPHALAKLLVVTKWNKHEDVAQMIYLLQSWPELPVLNALELLD
FSFPDRYVGAFTVNSLKKLTDADLFQYLLQLVQVLKYESYLDCELTKFLLGRALSNRKIG
HFLFWHLSSQKNAKPQTKEFMHTCMRQETYLEALSNLQSPLNPSVILAKVSVELCTFMDS
KMKPLWIVFNNEDAGGGHVGVIFKNGDDLRQDMLTLQMIQLMDILWKKEGLDLRMTPYGC
LSTGDKTGLIEVVMDSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILT
YDFVHVIQQGKTNNSEKFERFREYCERAYMILRCHGLLFLHLFALMKAAGLPELSCSKDI
QYLKDSLALGKTDEEARRHFQLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6Q2XBF3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLTSIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFEQVKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESAPELPQH
IYCKLDKGRLIVTIWVIVSPSNSKQKYTLKISHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYVRGCITMGRLPHLMLVSKDSLYSQLPGS
GFVAPSYSRRTPQPSPCPGGGDPSTPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDTLVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQVVLFPDEQQIEEHANWTISRELGYNYFAPTHLADGEQLRSLCSRDPLYELSEQEKD
FLWRHRHYCVNIPESLPKLLLSVKWNSRDEWSQMYCLLRDWPLMQPESALELLDCNFPDP
MVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFFW
HLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQK
TQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWDNPDIM
SELLFTNNEVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIE
VVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTRSCAGYCVATF
ILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQ
ECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALE
KSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>G1KQF3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anolis carolinensis|TrEMBL
MELEVNEQPVVMRDDNKRRRRRMKPYCTASSLSASELITIEFVLPTSNMLIDIASNCTVE
QMKAQIWMRAIERNQNSDYYHTFTPDQFVLQYQKKGQWYEIYDKHQIIQTLDCILYWKVL
QKKVGKIHVIQKQKPTKEVQEFQKQLNYLIGYDVTDISNVHDDELEFARRRLVTPRTIEV
SCRDPKLYSLHPWTTSKPLPDYMLSRIVNNSIFINIHRGTTSQKIKVAIDDTPDTILQSF
FTKMAKKKSLMNIPEDHNELDFVLRVSGRDEYIVGETPIRNFHWIRHCLKNGDEIHLVLD
DPPDPNQDEVQKEEWPLVDDCTGVSGYHEQLTIDGKDHERVFTISLWDCNRKFRVKIIGI
DIPVLPRNTDLTVFVEANIQHGQQLLSQKRTTAKPFTEEVLWNIWLEFDIKIKDLPKGAL
LTLQVYCGKAPASSTKANLQPHDSPSPDSKCKTQLLYYVNILLIDHRSLLRTGDYVLHMW
KISGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPVALPKHKIAADLQGDRARA
EMPNQLRKQLEEIIATDLLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQEVVT
ETYQLLAKRDAWDLSTLDVGLPMQLLDCNFSDENVRAMAVQKLESLDDDDVLHYLLQLVQ
AVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAHLRGCG
KAMLQDFLRQVQVIELLQKVTMEIKSLSAEKYDVTPQVITQLKQKLEKLQDCKFPECFRV
PYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTSLSNETIGIIFKHGDDLRQDMLIL
QILRIMESIWEEESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTGAFKDE
ILNQWLKEKCVIEEKFQTAVERFVYSCAGYCVATFVLGIGDRHNDNIMITEAGNLFHIDF
GHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPRFQNFQDICVRAYLALRKHTN
LLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFN
WFIHLVLGIKQGVEKHSA
>A0A096NPP4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Papio anubis|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNP
TGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKLLGGTLLASRGWRPELPWICLHAQD
SAPSRMMGVATPCLGVLPGLVQALGDAECSCLLQILELGRHSECVHVTEEEQLQLREILE
RRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQDALPAVSWPELPV
LSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDR
ALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSSGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8B7XDV0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcebus murinus|TrEMBL
MELENYEQPVVLREDNVRRRRRMKPRSAAASLSPMELIPIEFVLPTSQRHSKSPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQIHLVQRRAPSEETQVFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPSVTSKPLPEYLSKKIANNCIFIIIHRSTTSQTIKVSAEDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDGVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPILSGRVSADTSGPESKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPSPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPIEEKAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFH
IDFGHILGNYKSFLGFNKERVPFVLTPDFLFVMGTSGKKTSPYFQKFQDVCVKAYLALRH
HTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTV
QFNWFLHLVLGIKQGEKHSA
>A0A834EZC3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias melastigma|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDFEVQDFRRNILNVCKDAVELRDANGPHSRALYVYPPNVESSQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLSRLPNLMLMAKDSLYSQLPTD
SFVMPSYCRRISTATSYMNGEAAPKSLWTISGGLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLNYDMYILDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEHF
SSPVKYPDMNAVEEHANWTISRELGFNYNISGQSNRVARDHALTDSDSEQLKQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKFLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRYHSYFLCL
SALNISFILCLTASSLSLRMLPYGCLSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFN
SNTLHQWLKDKNRGEMYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHID
FGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECTKTKEFERFQEMCYKAYLAIRQ
HANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKGEQEALDYFMKQMNDAHHGGWTT
KMDWIFHTIRQHALN
>A0A3B4UQZ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola dumerili|TrEMBL
MDGQQIQVSDEEPKVLREDTRRRRRKKAITSSSGTSMDQITVEFVLPTVARGGSGPDSLL
LEVAGNWTVEQVKAQVWLKAVTSNLCPEFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKLLPEHLLSKVSNSHILVVIHITTASQTIKVSID
DTPAQVLASFFAKTANKRLLLGIPENMCEADYVLRVCGREEYLYGDKPLQNFNWIRQCLK
NGEEIHLVLEMPPDPDQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVVCGKQPLTPNSKGSSYQDNTGGGGSHDGKTKSRLLYYVNLLLIDH
RSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLP
KSRDVSRDAVAGGEEAEAGERGQREMPNHLKKQFGAIVATDPLHPLSPEDKELLWHFRQE
CMRDPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVR
SMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRS
EIAQSMHYQQRYAVLLEAYLRGCGEAMLQDYRKQVEMTEALQKVTREVKAMSADKYDVTA
QVVFQLRQKLETLQLSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPT
TLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEI
VKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYV
LGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKK
SSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSE
DDAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A6I9Y188|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Thamnophis sirtalis|TrEMBL
MELESSDQAVVMRDDNKRRRRRRMKPYCTANTLSSTELISIEFVFPTTSIVLDIPTNCTV
EQMKGQVWMRAVEGHQTSDLFRKITPDQFLLLYQKKGQWYEIYDKHQIMQTLDCILYWKV
LQKKVGKIHVVEKPNLSEEVQEFQNQLNYLIGYDVTDVSNVHDDELEFARRRLLTPRTIE
VSCRDPKLYSMPVWTTSKPLPEYLLSKIVHNNIFLNIHRGTTSQKIKVAVDDTPDVILQS
FFTKMAKKKSLMNIPEDHSEQDFVLRVSGRDEYIVGETPIKNFHWIRQCLKKGDEIHLVL
DEPPDPNQDEVQKEEWPLVDDCTGVSGYHEQLTIHGKDHERVFTISLWDCNRKFRIKIIG
MDIPVLPRNTDLTVFVEANIQHSQQLLSQRRTTAKPFTEEVLWNVWLEFDIKIKDLPKGA
LLTLQIHCGKTPAPSAKGNLHPHDSPSSDPKYKTQLLYYVNLLLIDHRSLLRTGDYVLHM
WKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHKIPSDPQGDRAR
VEMPNQLRKQLEEIIATDLLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQELV
AETYQLLAKREAWDLSTLDVGLPIQLLDCNFSDETVRTMAVQKLEGLEDDDVLHYLLQLV
QVCAGGARLLEILSSDSEGFPRRAAVGVFIDWLKEGHPEASPDPAEFVSRALQAADGDLD
WEVKIRALELAGVFIGQTFDGLGLGEGSASAGSSLAKTPAPLADALRLFCQMELFGFLFR
GLQDCDRPVALKACEVLLALKSVLCKHRSKSSPAGDAAGLKDIPMETPPPPPPLSLPAGE
AAEKDCQDPERLLLILESTDLEGLRKALDVSSDHLERNPESLLQDILAAAGNAEENKLTR
KSTVSRWFLRRHPESQFGQWVFLVGYSNFRDKISSLVGRREERKAGKEHGETGVQAITSS
NHLVNFVGKILWTKLDSAKWVEIVSHPSAVMTSLLDTECPNCACACPN
>A0A4W5PDC1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MPPAMTDDLDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFCPMLKLVTRSCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLMTWSEWLQACFSPQLEPGGG
APTTTDGVNNKQAEASLKVTMHFDQSQDTASLKVWPSTSPSELMEQALRKWLTTHGPEEE
GRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPHLTLVQVSSVQAMFEKEISA
IGAVVNRKSSNPPLPLPPKRRGPSQVNTCVWEVSTQFKIVLIKGSKVNAEETAKVQVRAG
LFHGTELLCKPAVSSESSGRSEHVWNRTLEFDITVSDLPRMARLCFAVYAVMDKVKKQKS
TKNAHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHSWSSFPDELEEMLNPI
GTIQTNPYTENATALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCSTMGRGGKKFHI
ELKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQ
IWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCAL
TRFLLNRAQCNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEAL
SKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSG
INVEKCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEA
NLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNS
GDALEKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFG
IKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTA
GLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A8C2XLK0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MPPAMTDLLDIWAAHSHLAGHALDKITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRAERLLD
SKIGVLISKGLHELDAINDQEVKDFRSKMFRLSEERMQQVQMMTCTEWLQACFSPQLEPP
AGTAITDGLNDRPADLKIIIHFDQSQDSASLKVPSSCVPSELMELALKKWLTTHGPEEEE
AWRGQYVLRVSHCLEFLCGDQPLIQYKYIRTCMQAKESPRLTLVHTSTVKAMFDKEISTI
GAVVGRKSSNPPLPLPPKRRVPTQVQTCVWDVSSSFKIVLVNGSKVNAEETAKVQVRAGL
FHGTELLCKPAVSSESSGRSDHTWKDSTLEFDLSVCDLPRMTRLCFAIYAVMDKVKKQKS
TKNAHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPI
GTIQTNPYTENATSLHINFPEYSSHSIVFPPFDKILEKAAEIARASDCVSMGRGGKKFHI
ELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQ
IWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSEEELSQYLLQLVQVLRYEPYYDCAL
THFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEAL
SKLKSVNELIKLGTIKTARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSG
INVERCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEA
NLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNS
GDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFG
IKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLVLRKNGNLFITLFALMLTA
GLPELTSVKDIQYLKDSLALGKTDEDALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A060XGA4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MEQQVSDEEESQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFN
IRIRDLPKGARLSLQVSCGKAQTQISKGTSSYQDNGGSPVGGGSGSHDCNKTKSRLXXLS
LSLSLSLSLSLSLSLSLSLALSLSLSLSL
>A0A8C7SG24|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRTKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVV
TSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPHFDKVHLILHTRFNIDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKLLLI
TKWNKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYL
LQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYC
RGNIYHIKSLCKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLL
SPLNPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDTVGIIFKNGDDLRQDMLTLQM
IQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKD
ALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFG
HFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTL
FVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNW
MMHSLAKDSRL
>A0A8C2ZSP9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MDGQQTQVSDEEPKVLREDTRRRRRKKAISSSSGASMDQITVEFVLPTAARGGSGPDTLP
LEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDAKLYSMDPWVTRKPLPEHLLTKVNAHVLMVIHIRTASQTIKVSIDD
TPVLVSFFAKTANKRVLLGIPDSMCEADFVLRVCGRFEYLYGDEPLQDFNWIRQCLKNGD
EIHLVLEMPPDTDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKF
RVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFSEEVLWNCWLEFNIKIK
DLPKGARLNLQVVCGKQPLTPNSKGASTYQDNTAGTGKTKSRLLYYVNLLLIDHRSLLRQ
GEFILHMWKMPEKSEESSSSINADKLTSATNPDKASAMAVAILLDKYCYPVVLPKSRNAG
NRDDGGRDREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECIRDPRAYPKLLGSV
RWGRQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDV
LRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVL
LEAYLRGCGEDMLQDFRKQVEMTEALQKVTREMKAMSADKCDITAQVVFQLRQKLETLQL
SGLPESFRVPYDPGLRAGALMIEQCKVMASKKKPLWLQFKRADPTTLSRDPIGIIFKDGD
DLRQDMLILQILLIMESIWETETLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVV
GSTGAFKDEILSQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITE
SGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKA
YLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAERHLLDQIEICR
EKGWMVQINWFVHLVLGIKQGVEKRST
>A0A8C9RBZ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHELFKEARKHPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDAVDLRDAGGPHSRALYVYPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLQYDMYIPDIPCAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SCPVKFPDVVTIEDHANWIISRELGFNYSQSGLSNRLARDNVLMDSDLEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYYLLKEWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEMIFKNGDDLRQDMLTLQIIRIMESIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDLAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8C9VQT8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MPPAMTDILDIWAADSQLSNEDYVTVDFLLPTGIYIQMEVPREATIQHIKLLLWKQASTY
PLFAFLGEMESHMFECVNQSAVHEALEDETRRLCDVRPFLPVLKLVPRNCGRAERLNSKI
GTLIGKGLHELDALQDQEVKDFRVKMFRISEEKMQRVQMMTWMEWLQSCFSPQLENGVID
GLQEKLFDGALKVIMHFDQSQDTASLMVSPTITPRELTEQAVRKWITTHGPEEDESSCGE
FLLRVSNKLEFLYGEHPLIHYKYVRACVIGKDTPHLTLVHCGMVQAMFEKELSAIGAVVN
RKTSNPPLPLPPKRPHDSVITHPWQIAPFKIVLVKGSKVNAEETAKVQVRAGLFHGTELL
CKPSVSTESSGRSEHVWNHTLDFDIAVCDLPRMARLCFAIYAVMDKVKKQKSTKNAHINK
YQTIRKAGKVHYPIAWVNTMVFDYRGHLKTGDNILHCWSSFPDELEEMLNPIGTVRTNPY
TENATALHIYFPEYSSCPVVFPPFDKVRTGRGGKKFHIELKEIMERDPLSQLCENEKDLI
WTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQY
VREYAVRCLKDMSDDELSQYLLQLVQVLRYEPYYDCALTRFLLERAQTNRKIGHFLFWHL
RSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKAVNELIKLGTIKNARKTK
EAMLTKEAMLTCLRQTGFTETLSDLHSPLNPSVVLSGINVEKCRYMDSKMKPLWIVYNNK
LLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEV
VSAAETIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALDRAIEEFTLSCAGYCVATY
VLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKT
GNTEKFGNFRQYCEDAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKT
DEEALKQFRQKFDEALRESWTTKVNWMAHNVAHNRS
>A0A8C9TUW1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MLEVCNDDQPVVFREENKRRRRKMKAFTSSVFKMTDLITVEFVLPTSPKTGKGFDSLQLD
VAGNCTVEQVKAQVWVKAIATNLCPEFYQKYSPDHCILLYQKKGNWYEIYDKHQVFQTLD
CICYWKTLKKEVGKIHLTIRPQLSEESIQYQKYLNYLIGYDVTDVSNVHDDELEFTRRKL
LTPRKNELLTRDPKIYSMDPWITTKPLPEYLLSKISKNHILLVIHRNTSSHTVKVSIDDT
PNQVLQSFFTKIAKKRALLGIPEEVSESDFVLRVCGREEYIYGNYAIKDFHWIRQCLKNG
DEIHLVLETAPDPEQDVVHKEDWSQVDICTGLAATHEQLTIDEKDHEKVFTISLWDCNRK
FRVKILGIDIPTLPRNSELIVFVEASIFHGQQLLAQEKTCPKPFTEEVLWNTWLEFNIKI
KDLPKGARLSLQVSCGKAQTQTQPSKTAYPDSASHESKSKSRLLYYVNLLLVDHRSLLRQ
GEYVLHMWKMPEKTEDLGSINADKLTSATNPDKGNSMAIAIMLDKYGYPVALPMSTEPSE
SSEGEDDERGHREMPSHLRKQLEQIVATDPLYPLSPEDKELLWHFRQECLRIPRAYPKFL
SSVKWGSQEAVLITHQLLARSSSWNQSPLDVGLAMQLLDCHFSDAMVRSLAVRKLEKLCD
DDVLRYLLQLVQAVKFEPYHDSALAQFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRY
AVILEAYLRGCGDAMLQDFRKQVEITEALQKVTREIKAMSVEKYDVSVQVVFQLRQKLEN
LQTSGLPESFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFRRADPTTLSSDTIGIIFK
DGDDLRQDMLILQILLIMESIWEAESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQ
STVGNTGAFKDEILNQWLRENCPTDDKFEQAVERFVYSCAGYCVATFVLGIGDRHNDNIM
ITESGSLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTTGKKSSPHFQKFQDVC
VKAYLALRHHTNMLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGRSEEEAQRHFLDQIE
ICRDKGWTVQFNWFLHLVLGIKQGGEKRSA
>A0A8C9TUW1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Osteoglossum formosum|TrEMBL
MLEVCNDDQPVVFREENKRRRRKMKAFTSSVFKMTDLITVEFVLPTSPKTGKGFDSLQLD
VAGNCTVEQVKAQVWVKAIATNLCPEFYQKYSPDHCILLYQKKGNWYEIYDKHQVFQTLD
CICYWKTLKKEVGKIHLTIRPQLSEESIQYQKYLNYLIGYDVTDVSNVHDDELEFTRRKL
LTPRKNELLTRDPKIYSMDPWITTKPLPEYLLSKISKNHILLVIHRNTSSHTVKVSIDDT
PNQVLQSFFTKIAKKRALLGIPEEVSESDFVLRVCGREEYIYGNYAIKDFHWIRQCLKNG
DEIHLVLETAPDPEQDVVHKEDWSQVDICTGLAATHEQLTIDEKDHEKVFTISLWDCNRK
FRVKILGIDIPTLPRNSELIVFVEASIFHGQQLLAQEKTCPKPFTEEVLWNTWLEFNIKI
KDLPKGARLSLQVSCGKAQTQTQPSKTAYPDSASHESKSKSRLLYYVNLLLVDHRSLLRQ
GEYVLHMWKMPEKTEDLGSINADKLTSATNPDKGNSMAIAIMLDKYGYPVALPMSTEPSE
SSEGEDDERGHREMPSHLRKQLEQIVATDPLYPLSPEDKELLWHFRQECLRIPRAYPKFL
SSVKWGSQEAVLITHQLLARSSSWNQSPLDVGLAMQLLDCHFSDAMVRSLAVRKLEKLCD
DDVLRYLLQLVQAVKFEPYHDSALAQFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRY
AVILEAYLRGCGDAMLQDFRKQVEITEALQKVTREIKAMSVEKYDVSVQVVFQLRQKLEN
LQTSGLPESFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFRRADPTTLSSDTIGIIFK
DGDDLRQDMLILQILLIMESIWEAESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQ
STVGNTGAFKDEILNQWLRENCPTDDKFEQAVERFVYSCAGYCVATFVLGIGDRHNDNIM
ITESGSLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTTGKKSSPHFQKFQDVC
VKAYLALRHHTNMLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGRSEEEAQRHFLDQIE
ICRDKGWTVQFNWFLHLVLGIKQGGEKRSA
>A0A8C5R8C4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptobrachium leishanense|TrEMBL
MGCGMWGRKVQRALFAYICMLLLPPIGDITAFVVLVIPMVTYTHRSNLQLPWRLAPNPEV
DAGSTRFGAHFGSRSSLGTYLSVPDSHRDMVCITGVSQRRKGKKERTQRSTETSLLLHEV
LYTPMFIASGMELDNNDQPVVLRDENKRRRRKMRPHSATINIFSMELIPIEFILPTSHKN
NKAPDTILLEIAGNCTVEQMKAQVWMNAIEKSHNSDFYHRLAPDQFLLQYQKKGQWYEIY
DKHQVIQTLDCIVYWKVLKKTVGKIYVVQKEKNSDETLEYQKQLNYLIGYDVTDVSNVHD
DELEFTRRRLVTPRMIELAKRDARLYSMDPWVTSKFLPEYLGRKISSNTIFIIIHKGMTS
HTVKVSINDTPDEILQSFFTKMAKKKSLLDISEENSELDFVLRVCGRDEYIFGNTPIKDF
HWIRQCIKNGDEIHLVLDAPPDPTDDKVQKEEWPLVDDCTGVTGYHEQLTIEEKDHEKIF
TISLWDCNRKFRVKVIGIDIPVLPRNSELTVFVEANIQHSQQLLAQKRTTSKPFTEEVLW
NTWLEFDIKIKDLPKGALLNLQIFCGKAVTPSNKTSLQSPDSSSSDSKCKNQLLYYVNLL
LIDHRFLLRQGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKDTSMAISISLDKYCHPV
ALPKNKSVVDAEQDRSRGEMPNQLRKQLEEIMATDPLHPLTPEDQELLWHFRYEIIKHPE
AYPKLFTSVKWGQQEIVTKTYQLLSKREAWDDCSLDVGLTIQLLDCNFSDENVRAMAVQK
LDSLPDDDVLHYLLQLVQAVKFEPYHDSSLSRFLLKRALRSKRIGHFLFWFLRSEIAQSM
HYQQRFAVILEAYLRGCGTAMLKDFMKQVQVTELLHKVTMEIKSLSAEKYDVTSQVITQL
RQKLEKLQGSKLPESFRVPYDPGLRAGLLMVEKCKVMASKKKPLWLEFKCADPTALTNET
IGIIFKHGDDLRQDMLILQILRIMGSIWEAESLDLCLLPYGCISTGNKIGMIQIVKDATT
IAQIQQSTVGNTGAFKDEVLSQWLKEKCPLEEKYNAAVERFVYSCAGYCVATFVLGIGDR
HNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLYFH
KFQDVCVKAYLALRHHSNLMIILFSMMLMTGMPQLTSKEDIEYIRDSLTVGKNEESAKKH
FLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A673AU60|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
MPPAMTDLLDIWVDHSPLAGHASDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRMSEERMQRVQMMTWMEWLQACFSPQLETS
GGATITDGVAERPADLKVIIHFDQSQDSASLKVPSSCTTAELMEMAVKKWLTTHGPEEEA
WRGQYVLRVSHCLEFLCGDHPLILYKYIRLCIQVKEPPHLTLVHTSTVKAMFDKEISAIG
AVVSRKSSNPPLPLPPKRRQVQTCVWDVSSLFKIVLVSGSKVNAEETAKVQVRAGLFHGT
ELLCKPAVSSESSGRSDHTWKDSTLEFDIAVCDLPRMTRLCFAIYAVMDKVKKQKSTKNT
HLNKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQ
TNPYTENATALHIHFPEYSSHPIIFPPFDKILEKAAEIARASDCAPMGRGGKKFHIELKE
IMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPK
LSPRDALELLDFNYPDQYVREYALKHFPSASLFSHSLVSHLSDEELSQYLLQLVQVLRYE
PYYDCALTHFLLQRAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVL
KKQVEALSKLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLN
PNILLVEKCRYMDSKMKPLWIVYNNKLLGGDTRGIIFKNGDDLRQDMLTLQILRLMDLLW
KEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKE
RNSGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKS
KFGIKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGTLFITLFALM
LTAGLPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKD
NRS
>A0A8B9TWR4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos|TrEMBL
VVWKHAQYEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGD
RVKKLINSQISLLIGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNF
PLQLEPMAKGFGTGLLHTPTKNIFVNVKFQSGGESFTFQIAPDEFPITLMSYAIKKQATV
FRHETMESPEDYTLQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRD
EQINCIANTPKMSAKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGL
FHGNEMLCKMVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARST
KKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTES
AASLVICFPNVASHPVYYPSFEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQ
ALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLT
DNELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRF
GLILEAYCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCMKQETY
LEALSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIFKNGDDLR
QDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMV
ATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETG
QLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYM
ILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRE
SWKTKVNWLAHNVSKDNRQ
>A0A7K7R325|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecile atricapillus|TrEMBL
MPPGIYCPTEFWSKGEHQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLGWAAWMEYNFPLQLEPMAKGPGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQNSCFTSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLDFDINICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAVPEDSEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
AAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q1HB14|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MLARLLLPALKNFLCCKPVVLREEIRRRRRKKAITSSSSISMDQITVEFVLPTATWGSNP
DSLQLEVAGNWTVEQVKAQVWLKAVTSNLCPEFYQRFSPDHCILLYQKKGNLCEIYDKHQ
VFQTLDCIRYWRALKKDVGKIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELE
FTRRKLLTPRRIELCDRDPKLYSMDPWVTRKPLPEHLLSKVSNGHILVVIHMSTASHTIK
VSIDDTPAQVLASFFNKTANKRVLLGIPDNVCETDYVLRVCGRYEYLYGDKPLQNFNWIR
QCLKNGEEIHLVLETPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISM
WDCNRKFRVKVLGIDIPTLPKVPEFVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWL
EFNIKIKDLPKGARLSLQVVCGKQPQTPNSKGSSYQDNTTKSRLLYYVNLLLIDHRSLLR
QGEFILHMWKMPEKSEESSSSINADKLTSATNPDKESSMAIAILLDKYCYPVVLPKSRDV
GRDVGAVGEESEGGERGQREMPNHLKKQFEAIVTTDPLHPLSPEDKELLWHFRHECMRDP
RAYPKLLGSVKWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVR
KLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQS
MHYQQRYAVLLEAYLRGCGEAMLQDFRKQVEMTEALQKVTREIKTMSADKYDVTAQVVFQ
LRQKLEILQSSGLPDNFRVPYDPGLRAGALMIEQCKVMASKKKPLWLQFKKADPTTLSKD
PIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDAT
TIANIQQSVVGSTGAFKDEILYQWLRDKCVSEEKFQQAVERFLYSCGGYCVATYVLGIGD
RHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHF
QKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQR
HLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A7N6C1U3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPAMTDLLDMWAAHSPLAGQTPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
NFPLFPALGEMESHMFECVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRISEEQMQRVQMMTWKEWLQACFSPQLEPA
AGTAITDGVNDRPADLKVTIHFDQSQDSASLKVPATCTPLEVIELSMRKWLTTHGPEEEE
WRGQYVLRVSHCLEFLCEEISLFQYKHVGLLIFTVHYANTAHSQQVSLSPLIFPLQQLQT
CVWDVPSPFKIVLVNASKVNAEETAKVNVRAGLFHGAELLCKPAVSSESSGRSDHTWKEN
TLEFDIFVNDLPRMTRLCIAIYAVMDKVKKQKSTRNAHINKYQTIRKAGKVHYPIAWVNT
MVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATALHIHFPEYSSHPI
VFPPFDKVRHFSVIARSCGHHHRNSCLFGRGGKKFYIELKEIMERDPLSQLCENEKDLIW
TLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLCPRDALELLDFNYPDQYV
REYAVGCLRDMSDEELLQYLLQLVQVLRYEPYYDCALTHFLLERAQGNRKIGHFLFWHLR
SEIHMPAVSVQFALILEAYCRCNIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSKTK
EAMLTKEAMMTCLRQSGYSETLSDLQSPLNPNVLLSGINVDKCRYMDSKMKPLWIVYNNK
LLAGDNLGIIFKNGDDLRQDMLTLQILKLMDLLWKEANLDLRIVPYACLATGDRAGLIEV
VSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFTLSCAGYCVATY
VLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKT
GYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKT
DDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7K7C7R8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aphelocoma coerulescens|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSVSVDFLLPTGIYINLDVPRDATISQIKQLLWKQA
HSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTTVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGHLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C3KBM6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calidris pygmaea|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMTKGLGA
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGDQPRQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQ
ALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYGDCEQDNELFQYL
LQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYC
RGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHVCMKQETYLEALSHLQ
SPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQM
IQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKD
ALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFG
HFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLL
FLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNW
LAHNVSKDNRQ
>A0A8C3KDK2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calidris pygmaea|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMTKGLGA
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSTIIAMRDEQTNCIASPPKMT
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGDQPRMISLLQSWPELPVLNALELLDFSFPDRYVGSFAINSLK
KLTPFLFMFRAVEGDYNELFQYLLQALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAY
CRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHVCMKQETYLEALSHL
QSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQ
MIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNK
DALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDF
GHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGL
LFLHLFALMKAAGLPELSCSKDIQYLKVREAEPREG
>A0A8C3KDU9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calidris pygmaea|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMTKGLGA
GPLHTPTKNIFVNVKFQSGGVNFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQVSFLSCFVNESVPVCPPPPRGVKSLWILMVFSYFSFPQLV
VQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAK
KARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCN
PNTESAAALVICFPSVASHPVYYPSFDPVYALSCDSHEQKLQLKEILERRSHTELYEHEK
DLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFP
DRYVGSFAINSLKKLTDNELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLF
WHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATK
PQTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEET
GGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVM
HSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVL
GIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNN
NEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDE
EALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6J2WQI4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chanos chanos|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESSPELPKH
IYAKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASAKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SCPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTESDIEQLRQVGTRDPL
SEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDNAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVITKGSQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A8C7AQB1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neovison vison|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSEETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMIEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFAKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIRNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCSKTPALSSKVAAESPSSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDHGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVHVIETLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNANLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSSETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8C7BFI8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neovison vison|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K5S2F4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lanius ludovicianus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GSLQIPAKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRHD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDTLDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A672LFD2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDGTRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYSMPLEAGSLE
NLIDKHEGIIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHCPEEDIGFRSDY
VLRVSGKLEFLFEDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIGSVLAR
KTSNPPLPLPPKKRLPTASTLFPALQLMQGVLSFAYLAVRAGLFHGTELLCKTAVSSESS
SRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKV
HYPIAWVNTMVFDYRGQLKTGDIILHCWTSFPDELEEMLNPIGTIQTNPYTENATELHIS
FPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMERDPLSQLCENE
KDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMTQLQALLQIWPKLSPRDALELLDFNY
PDQYVREFAVYCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFL
FWHLRSEMFMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFGTIKTK
TKQAHLKEAMMTYLCVVERCKYMNSKMKPLWIVYNNKLLEGDTVDIIFKNGDDLRQDMLT
LQILRLMDLLWKEAKLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAF
NKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHI
DFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKN
GNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTK
VNWMAHIVAHPS
>G3SRN1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Loxodonta africana|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKISHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWSEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFNYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C9MWE7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Serinus canaria|TrEMBL
MELGDHDQPVVMRDENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQILSQRRTSSKPFTEEVLWNMWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A834V2J5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Marmota monax|TrEMBL
MLWKQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCD
PAEKLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRIFSEEKIQSLVGLSWIDWLKQTYP
PEHEPSTLENLEDKLYGGKLIVAVHFENCQDVFSFQVSPEMNPIKINELAIQKRLTIHGK
EDEASPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECSKIKKMYEQEM
IAIEAAINRNSSNLPLPLPPKKTRVISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGL
FHGTELLCKTIVSSEISGKNDHIWNELLEFDINICDLPRMARLCLAVYAVLDKVKTKKST
KTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMG
TVQTNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVASRGGKKFLAV
LKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQI
WPKLSPRDALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALS
RFLLERALANRRIGQFLFWHLR
>A0A673UJ41|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Suricata suricatta|TrEMBL
MELDSYEQPVVLREENRRRRRRMKPRSTTASLSSMELIPIEFVLPTSQRNSKTPETALLH
VACHGNVEQMKAQVWLRALETSVAADFYRRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQIHLVQRQTPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCSKVPVLPGKASAETPSSESRGKTQLLYYVNLLLIDHRFLLRYGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLQDFTDQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKEATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQCNWFLHLVLGIKQGEKHSA
>A0A7N8YK52|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MDRQQIQVSDEEPEIVHEEFRRRRRKKAFTSSSSTSMDQITVEFVLPTAGWAGNSPDTLQ
LEVAGNWTVEQVKGQVWLKAVTMNLSPDFYQRFSPDQCILVYQKKGSVCEIYDNPEQICP
FLVPRPQPSDESQQYQRYLNHLIGYDVTDVSNVHDDELEFTRRKLLTPRRIELSDRDSKL
YSMDPWVTRKPLPEHLLSKVSNGHILLVIHTGTARQTIKVSINDTPVQVLASFFTKTTNK
RGLLGIPENMCEADYVLRVCGREEYLYGDQPLQNFNWIRQCLKNGEEIHLVMEMPPDPDL
DLVQKEDWALVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVLGIDIPSLPK
IPELIVFIEASIFHGQQLLAQERTISKTFNEEVLWNCWLEFNIKIRDLPKGARLNLQVVC
GKQSQTVQNEPYFSPFVRLSGKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEE
SSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDVGAAGEESEGGERG
QREMPNHLKKQFEAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRWGKQED
VLITHHLLERSNAWDTSDLDVGLAMQLLDCHYSDAQVRTMAVRKLETLEDDDVLRYLLQL
VQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEISQSMHYQQRYAVLLEAYLRG
CGEAMLQDYRKQVDMTEALQKVTREIKAMSADKYDVTAQVVFQLRQKLETLQISGLPESF
RVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQDML
ILQILLIMESIWETEALDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFK
DEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHI
DFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRTEDEAQRHLLDQIEICREKGWMVQ
INWFVHLVLGIKQGVEKRST
>A0A672J558|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salarias fasciatus|TrEMBL
MDRQQMQVSDEEPEVLRQESRRRRRKKAITSSSCASMDQITVEFILPTATRGGNAPDTLQ
LEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCMLLYQKKGNICEIYDKHQVFQT
LDCIRYWKALKKDVGRIQLVPRPQPSDESVHYQRHLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELLDRDPKLYSMDPWVTRKPVPEHLLTKVNNGHILLVIHVGTASQTIKVSID
DTPSQVLSSFFTKMTNKRVLLGIAEDQCEADFVLRVCGREEYLYGEKPLQNFNWIRQCLK
NGEEIHLVLEAPPDPDLDQVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RRFRVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFGI
KIKDLPKGARLNLQVICGKQPQTPNSKSGSYQDSPAGSGTLEGKTKSRLLYYVNLLLVDH
RSLLRQGEYILHMWKMPEKSDESSSSINADKLTSATNPDKASSMAVAILLDKYCYPVVLP
KSREGGRDGGGGEEAEGGDRGQREMPNHLKKQFEAIVRTDPLHPLSPEDKELLWHFRHEC
MRDPRAYPKLLGSVWWGKQEDVLATHRLLDRSSAWDTSGLDVGLAMQLLDCHYSDAQVRS
MAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSE
IAQSMHYQQRYAVLLEAYLRGCGGAMLLDFRKQVEMTEALQKVTREVKTMSAEKYDVTAQ
VVFQLRQKLETLQLSGLPQSFRVPYDPGLRAGALMIEQCKVMASKKKPLWLQFKRADATT
LSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIV
KDATTIANIQQSVVGSTGAFKDEILYQWLRDKCASEDKFQQAVERFLYSCGGYCVATYVL
GIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKRS
SPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSED
EAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A8D1WCQ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MCFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDYPLIQFQHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGL
FHGTELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKST
KTINPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMG
TVQTNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSIGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8D1WC69|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MCFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDYPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSVRKIDHFAKFLNQ
FHFFFKQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLV
QVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSV
GHMKALSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMHTCLKQSAYREALSDLQSPLN
PCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSIGVIFKNGDDLRQDMLTLQMLRLM
DLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLN
WLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILG
NFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITL
FALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHT
VRKDYRS
>A0A6G0HRE5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Larimichthys crocea|TrEMBL
MDGKQTPVSDEEPRVLREDTRRRRRKKAITSSFSASMDQITVEFVLPTAARGGNSPDTLQ
LEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSEESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLNKVSNNHILVVIHIGTASQTIKVSID
DPPAQVLASFFTKTANKRVLLGIPDNMCETDFVLRVCGREEYLYSDKPLQDFNWVRQCLK
NGEEIHLVLETPPDPDLDLVRKDDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVVCGKQPQTPNSKGGSSYQDNTAGTGSHDGKTKSRLLYYVNLLLID
HRSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVL
PKSRDVGRDLGAGSEEAEGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRH
ECMRDPRAYPKLLSSVRWGKQEDVLAAHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQV
RSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLR
SEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTRDVKAMSADKYDVT
AQVVFQLRQKLESLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADS
TTLSKDPIGIIFKHGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIE
IVKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATY
VLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGK
KSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRS
EDEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A0S7GKX6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poeciliopsis prolifica|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRNASGPHSRALYVYPPNVESTQELPKH
IHSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVSFINHT
>A0A218UIB6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lonchura striata domestica|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPAAKGLGA
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAAPKPPPLPKKKPNYGSLWS
LEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSEVSVCSEPVWRQRLDFD
ISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECC
LHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHPVYYPSFEQLLELGRNG
EQPRAAPEDSEEKLQLREILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLVITKW
NKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAVNSLKKLTDDDVFQYLLQL
VQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGS
THHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCMKQETYREALSHLQNPL
NPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQL
MDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALL
NWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRETGQLFHIDFGHFL
GNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCERAYMILRRHGLLFLH
LFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFNEALRESWKTKVNWLAH
NVSKDNRQ
>A0A8B9MA08|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Accipiter nisus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A850TQC6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Grus americana|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSTNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEISQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKTQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L1P8Q2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oriolus oriolus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSGFSSMELISIEFILPTSNKHTKAPEVMLLE
IAGNCTVEQMKAQVWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFITIHGGTTSHKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNVWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIVATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A093QIY0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Manacus vitellinus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYIIGETPVKDFHWIRQCLKNG
EEIHLVLDDPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDTKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQ
>A0A667HEQ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lynx canadensis|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINICDLPRMARLCFAIYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3B3T824|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Paramormyrops kingsleyae|TrEMBL
MEQNVYDDDQPVVFREQNRGRRRKMKAFTSCNFKAMDMITVEFVMPATTKTGKGLDSLQL
DVAGICTVEQVKTQVWMKAITTNLCSEFYQKYSPDDCILLYQKKGNWYEIYDKHQVFQTL
DCICYWKTLKKDVGKIHMTTRPQLTDESIQYQKYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRKNELLTRDPKLYSMDPWVTSKPLPEYLLSKISKNHILLVIHRNTSSLTVKVSIDD
MPIQVLQSFFTKIAKKRALFGIPDEVSESEFVLRVCGREEYIFGNNPIKDFYWIRQCVKN
GEEIHLVLETPPNPEKDVVHKEDWSQVDMCTGLAASHEQLTIDEKDHDKVFTISLWDCNR
KFRVKILGIDIPTLPRNSELIVFVEASIFHGQQLLAQEKTSPKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTQATKGPYSESPTYEGKSKSRLLYYVNLLLVDHRSLLR
QSEYVLHMWKMPEKSEDLGSINADKLTSATNPDKAGSMAIAIMLEKYGYPVALPMSPEPP
ESPEGAEDERGLREMPSHLRKQLEQIMATDPLYPLSPEDKELLWHFRQECLRIPKAYPKF
LGSVKWGNQEAVMITHQLLARSFTWAQSPLDVGLAMQLLDCHFSDAIVRSLAVKKLEKLG
DDDVLRYLLQLVQAVKFEPYHDSALAQFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQR
YAVILEAYLRGCGEAMLQDFKKQVEMTEALQQVTREIKAMSAEKYDVSVQVVFQLRQKLE
NLQSSGLPESFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFRRADPTTLSSDTIGIIF
KDGDDLRQDMLILQILLIMESIWEAESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQ
QSTVGNTGAFKDEILNQWLREKCLTEEMFEQAVERFVYSCAGYCVATFVLGIGDRHNDNI
MITESGSLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTTGKKSSPHFQKFQDV
CVKAYMALRHHTNMLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGRSEDEAQRHFLDQI
EICRDKGWTVQFNWFLHLVLGIKQGGEKRSA
>A0A673ZFH4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MYSPFKRECSNSDWVLVPAMPPAMPDDLDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVP
REATIQHIKLLLWKQAQSYPLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFCP
MLKLVTRNCGRAERLLDSKIGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQRVQLM
TWSEWLQACFSPQLEPGGGATPLTDGVNDKQAEASLKVTMHFDQSQDTASLKVWPSTSPS
ELMEQALRKWLTTHGPEEEGRQAEQYVLRVSDKLEFLCGDHPLIQYKYIKACLQAKECPH
LTLVQVSSVQAMFEKEISAIGAVVNRKSSNPPLPLPPKRRGPSVSTQFKIVLIKGSKVNA
EESAKVQVRAGLFHGTELLCKPVVSSESSGRSEHVWNRTLEFDITVSDLPRMARLCFAVY
AVMDKVKKQKSTKNAHINKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKTGDIILHSWSSF
PDELEEMLNPIGTIQTNPYTENSTALHIHLPDYNPHPILFPPFDKILEKAAEIAGSSDCS
TMVLSRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWS
KHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSSLTVVMIYSLPL
SPSSPPLPLSDEELSQYLLQLVQVLRYEPYYDCALTRFLLNRAQCNRNIGHFLFWHLRSE
MHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNARSKTKEA
MLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMDSKMKPLWIVYNNKLL
GGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRSGLIEVVS
SADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKAIEEFTLSCAGYCVATYVL
GIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGN
TEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKVIGRFTWDSL
ALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A667YXL6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDTNGPHSRALYVYPPNVESSAELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDWVPEQVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKPLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLSYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKFPDMTTIEEHANWNISRELGFNYCHSGLSNRLARDNPLTDSDSEQLRLVCNRDPL
SEITEQEKDFLWRHRHQCVSMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLYSPRTHPLCSSHFC
LPYPPSPDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIM
QIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRSCAGYCVATFILGIGDRHN
SNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFE
RFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQEALDY
FMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A674CST1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPRPSSGELWGMHLMPPSIQVDCLLPNGMILTLVCTREATLISVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKESVDLRDTNGPISRALYVYPPNVESSVELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNAIGVTGSNPNKETPCLELEFDHF
SNPVKFPDMPAIEEHANCNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCGTIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQSNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A667Z5W5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDTNGPHSRALYVYPPNVESSAELPKH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDWVPEQVIAEAIRKKTRSMLLSHEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKPLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLSYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKFPDMTTIEEHANWNISRELGFNYCHSGLSNRLARDNPLTDSDSEQLRLVCNRDPL
SEITEQEKDFLWRHRHQCVSMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDRLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLYSPRTHPLCSSHFC
LPYPPSPDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIM
QIQCKGGLKGALQFNSHTLHQWLKDKNRGEMYDQAIDLFTRSCAGYCVATFILGIGDRHN
SNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFE
RKPPAVCISSQDFFQFFPIIQFFSHSL
>A0A7J6A971|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ameiurus melas|TrEMBL
MEQNVSDDDSPVVRRGDTRRRRRKMKAFTSNSSAAMDHLALEFVLPTTNKTTKNPDTLQL
DVIGNWTVEQVKAQLWLRAVTTNVCPEFYQKYSPDHCILLYQKKGSWYEIYDKHQVFQTL
DCIRYWKALKKEVGKIYLVLRPQPSDESIQYQKFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTTRKIELADRDPKLYSMDPWITTKPLPDYLLSKVANNNILIVIHKDTSSQTIKVSIDD
TPFQVLQSFFIKTTNKRALLGMPEDADESDFVLRVCGRDEYLFGNYPIKDFHWIRQSLKT
GEEIHLVLESPPDPEQDVVQKEDWSQVDDCTGVAGTHEQLTINEKDHEKVFTVSLWDCNR
KFRVKILGIDIPVLPRNSDLIIFVEASIFHGQQLLAQERTSSKPFTEEVLWNTWLDFNIK
IKDLPKGARLNLQVSCGKAQTQTSKDNVSHDCKNKNRLLYYVNLLVVDHRSLLRQGEFIL
HMWKMPEKSEDNSSVNADKLTSATNPDKTSSMAIAVLLDKYCYPVALPKSRDSRDTPETD
GERGKREMPNHLRKQFDQIVATDPLHPLSVEDKELLWHFGHECVRHPTAYPKFLGSVKWG
KQEAVMATHRLLERSTAWDQSPLDVGLAMQLLDCHFSDANVRTMAVRKLETLGDDDVLRY
LLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEA
YLRGCGDEMLQDFRKQVEITEALQKVTREVKAISAEKYDVSAQVVFQMRQKLESMQMQGL
PESFKVPYDPGLRAGSLVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLR
QDMLILQILLIMESIWETESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNT
GAFKDEILNQWLRDKCLNEDKYQQAVERFVYSCGGYCVATYVLGIGDRHNDNIMVTESGN
LFHIDFGHILGNYKSFLGITKERVPFVLTPDFLYVMSTTGKKTSQNFLLFQNICVKAYLA
LRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGCTEDVAQRHFLDQIEICRDKG
WTVQFNWFLHLVLGIKQGVEKRSA
>A0A7K5UH41|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cephalopterus ornatus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPIAKGFGT
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPVTLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A226MTN5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callipepla squamata|TrEMBL
MHSSYYYFFFQLLWKQAHSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDIRPFL
PVLKLVTRNCDPGEKLDSKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGL
SWMDWLKHTYPPEQEPVIPENFQDKLYSGNLVVAIHFDNCQDVFSFQVSPNMNPIKLNEL
AIRKRLTIHGKEDEEIDPADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVE
CCTIKKMCEQEMIAIEVAINRKSSNLPLPLPPKKTRATTSVWDICSPFKVILLKGNKLNT
EENAKVHVRAGIFHGTELLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVY
AVMDKMKTKKSTKSMNPSKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGEFVLHSWSSF
PDELEEMLNPMGTVQTNPYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNA
AMAGRGGKKFYIVLKEIMERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNK
LEDVAQLQALLQIWPKLLPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQ
VLKYEPFLDCALSRFLLERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVA
HMKVLAKQVEALNKMKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYKEALSDLQSPLNP
SVILSELHVEKCKYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMD
VLWKEAGLDLRILPYGCLATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNW
LKEYNLGDDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGN
FKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLF
ALMLTAGLPELTSIKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTV
RKDYRS
>A0A7K5L1J9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Vireo altiloquus|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSEFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQNNCIASPPKAA
SKPPPLPKKKPNCGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKSGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>G7NZ32|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca fascicularis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7N9D5S0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca fascicularis|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPFSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDIHICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPK
PQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEA
GSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVV
LRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYV
LGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTN
NSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTE
EEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L3I1G1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pardalotus punctatus|TrEMBL
MDLGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNCDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEVKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A0P6JG58|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Heterocephalus glaber|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
CHGGEPLCDNVNTQRVPCSNPRWNEWLNYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A7K5X4Q4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dromas ardeola|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHDDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L3FR85|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zapornia atra|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPEEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGRTPHLTMVHSSAIIAMRDEQTNCIASPPKMS
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSIAL
HPVYYPSFEQLLELGRNGEPPRTAPEDPEEKLLLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDQELFWYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNDFVKASSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKIKVNWLAHNVSKDNRQ
>A0A099ZMR4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tinamus guttatus|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRQVSEEKIRSLVGLSWMDWLKHTYPPEQEPV
IQESFQDKLYSGNLVVAIHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKDDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AANRKSSNLPLPLPPKKTRTTTSVWDICNPFKILLLKGYKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNETLEFEINVCDLPRMARLCFAVYAVMDKVKTKKSTKTMNP
PKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELILHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIAKSSDNAAMAGRGGKKFYVVLKEI
MERDPLSQLCENEMDLIWTLRYDCRESFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVSCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCKYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C6K7J9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Melopsittacus undulatus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GPFHIPTKNIFVNVNFTFQISPNEFPITLMSYAIKKQATVFRHETVEKPEDYTLQVNGKC
EYLYGNYPLYQFQVSLMSCFVNESVPIAGRKSLLCLFLIGGTLFSSQPNYGSLWSLEQSF
YIQLVQGSKVNADEGMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWQQRLDFDINICD
LPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWS
SFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVASHPVYYPSFEQDSSLVTTREGRSK
LQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLL
QTWPELPVLNALELLDFSFPDRYVGSFAVNSLKKLTDHDVFQYLLQLVQVLKYESYLDCE
LTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKILMKQGEA
LNKMKALNDFVKASSLKATKPQTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQ
CTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLR
MTPYGCLSTGDKTGLIEVVMQSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALE
QAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRER
VPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPEL
SCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKNNRQ
>A0A1A6HB04|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neotoma lepida|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEVAARRQQLGWEDWLQYSFPLQLEPSARSWRA
GILRVTNRALLVNVKFEGXEDSFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPAKKPSSVSLWSLEQPFCIELIEGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVICLPEILE
LGCLGERGRITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQEHFPEALARLLLVT
KWNKHEDVAQVSREGRLGKEPGADGQLPPTPHLTTKLSQMLYLLCSWPELPVLSALELLD
FSFPDCYVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIG
HFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQ
KTTKPQTKEMMHMCMRQEAYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPXWIVYN
SEEAGSAGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGL
IEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDNIMIRESGQTKFGINRER
VPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRSRAPQCR
SAVMFVQDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>L5KPB2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pteropus alecto|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWL
KFSSVKFPDMSVIEEHANWSVSREAGFSYAHAGLSNRLARDNELRENDKEQLRAICTRDP
LSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAM
ELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDIL
KQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3B3WN43|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poecilia mexicana|TrEMBL
MPPGKYGTQEEWEQDGDREIYMDFLLPTGIFLKFPVSRNDTIRNIKKMVWKNASREPLFF
GLGDPDLYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRSEKLTNAQISLL
IGKGLHEFEAQKNHEVDEFRTKMRTFCEEKSLERQNLPWQRWMEYSFPCELEPCSSPATG
GSSKSKHGKKLFVNIKFESSDESFMLQQDSQDLPVALMKSALKKKATVFRSVRQEPEDYT
LQVNGRWEFIYGQHPLCQFKYIFFCMRNGQNPQLTMVHHSTISKYQEDQGRVCSQMYKTR
SLSRPPPLPLKKLVVQAGLFHGSELLCKMMTSSEVTVCSEPLWDQRLEFDINVSDLPRMS
RLCFALYAVIEKTKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGDFLLSMWPSVPDD
KSDLLNPMGTVQKNPNVDSAAGLLIRFPNIRPHPLYYPPLEKTIDPEMNGNTDFPSKDEY
LKLKEIMDNKNYTEFFEDEKELLWKLRIEVRDYFPECLSKLLLITKWNKREDVVQMVSLL
KSWPELPAIQALELLDYSFPDPAVRYFTIRCLKKLSDDELLQYLIQLVQVLKYESYLDCD
LTTFLLERALSNRRIGHFLFWHLKSEIHVASVSLRFGLILEAYCRGNIHHIKLLSKQNEA
LGKMKALSDIVKTGSQKMTVDDLKLCIRQESYLEALSDLLSPLNPSVILFEICADKCRFM
DSKMKPLWLMYKNPLEQADMVGIIFKNGDDLRQDMLTLQMIRLMENLWKKEGLDLRMIPY
GCLSTGNKTGLIEIVKSSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPGDKLDQAIE
EFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFI
LTYDFVHVIQQGRTNNSEKFERFREYCEKAYKILCRNGTLFVNLFAMMKAAGLPELSSSK
DIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A7R5K184|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pipra filicauda|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSTLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTTVSTEISGRSDHVWNEELEFEINHYPVAWVNTMVFDYKGHLKNGELVLHSWSSFPDEL
EEMLNPMGTVQTNPYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAG
RGGKKFYVVLKEIMERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDV
AQLQALLQIWPKLLPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKY
EPFLDCALSRFLLERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKV
LAKQVEALNKMKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVIL
SELHVEKCRYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWK
EAGLDLRILPYGCLATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEY
NLGDDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSK
FGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALML
TAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDY
RS
>A0A8C7ZW90|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias sinensis|TrEMBL
MHPGIYGMLEEWEDGDQEINMDFLLPTGIFLKFPVSRNDTIKHIKEMVWRNARSEALFSG
LGDPDGYVFTCINQTAEREELEEEFRRIRDVKPFMCVLRLVAREGNRQEKLTNTQITQLI
GKGLHEFESQKNHEVNEFRTKMRTFCEEKALERQYLPWQRWLEYSFPCDLEPCRTPSGFG
SVKLKSSKIFINVKFEASDVSVEVSQLNALKKKATVFRSLRQEPEDYILQVNGRWDFIYG
KHPLCQFKVSRENKLKHLYMYIQHKKRKNLIFDSFPQQNTSSLWSINEPFYIQLLQGSRV
NADEGMKLVVQAGLFHGSELLCKVVTSLDVTVCSEPLWDQRLEFDINVCDLPRMSRLCFA
LYAVIEKTKKPKSTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSMWPSVPGIDLLNP
MGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPSLEKIIDFEKNGDVHLKLKEIMDNKHYTE
FFEDEKDLLWKLRTEIREHYPENLSKLLLVTKWNKREDVVQMVSLLKKWPDLPAIHALEL
LDYSFPDPAVRSFTVRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRR
IGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIKILNKQNEALAKMRALSDFVKSG
SQKMTVEDLKLCIRQETYMEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNP
STPGDMVGIIFKNGDDLRQDMLTLQMIQLMENMWKKEGLDLRMIPYGCLSTGNKMGLIEV
VKNSDTIANIQLNSSNSAATAAFNKDALLNWLKSKNPGDKLEQAIEEFTLSCAGYCVATY
VLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRT
NNSEKFERFREYCEQAYKILCRNGMLFVNLFAMMKAAGLPELTCFKDIQYLKDSLALGKS
EDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRA
>A0A3B4XYX8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola lalandi dorsalis|TrEMBL
MKPKVLREDTRRRRRKKAITSPSGTSMDQITVEFVLPTVARGGSGPDSLLLEVAGNWTVE
QVKAQVWLKAVTSNLCPEFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDCIRYWRAL
KKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPRRIEL
SDRDPKLYSMDPWVTRKLLPEHLLSKVSNGHILVVIHITTASQTIKVSIDDTPAQVLASF
FAKTANKRPLLGIPENMCEADYVLRVCGREEYLYGDKPLQNFNWIRQCLKNGEEIHLVLE
MPPDPDQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVLGI
DIPSLPKIPEFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKIKDLPKGAR
LNLQAYLCLFVLVSGKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEESSSSIN
ADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVSRDVSRDAVREMPNHLKKQFGAI
VATDPLHPLSPEDKELLWHFRQECMRDPRAYPKLLGSVRWGKQEDVLATHRLLERSSAWD
SSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALV
RFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEAMLQDYRKQVEM
TEALQKVTREMKAMSADKYDVTAQVVFQLRQKLETLQLSGLPESFRVPYDPGLRAGALLI
EQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETE
SLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFKDEILYQWLRDKCVSE
DKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGI
SKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTG
MPQLTSKEDIEYIREALTVGRSEDDAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGV
EKRST
>A0A3Q2U007|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fundulus heteroclitus|TrEMBL
MPPRPSSGELWGLHLMPPRIHVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRNASGPHSRALYVYPPNIESTEELPRH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSTEQLK
QCVLEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCMMLGRMPNLMLMSKDGLYTQLPTD
NFVMPSYSRRISTAASYMNGEASFKSLWSIKETLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICAVKGRKGAKEEHC
PLSFGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEHF
SGPIKYPDMKAVEDHANWITSRSGRVARDHALTDSDSEQMRQLSNRDPLSEITEQEKDFL
WRNRSYCMKMPEILPKILLAVKWNSRDEVAQTYCLLKELPSLLPEEAMELLDFNYPDPLV
RHFAVRCLDENLTDDKLSQYLIQLVQVLKYEQYLDSPLARFLLKKALTNQRIGHFFFWHL
KSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVR
YYFCSFVFMLKGFVLLAEDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVV
RNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDNAVDLFTRSCAGYCVATFIL
GIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQEC
TKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKT
EQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHQLN
>A0A6P4W7Q4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panthera pardus|TrEMBL
MPPFHCLARPIRVDIHKVPAIALQVAQGMELDNYEQPVVLREDNRRRRRRMKPRSTTASL
SSMELIPIEFVLPTSQRNSKTPETALLHVAGHGNVEQMKAQVWLRALETSVATDFYRRLG
PDHFLLLYQKKGQWYEIYDKYQVVQTLDCLRYWQVLHRSPGQIHVVQRHAPSDETLAFQR
QLTALIGYDVTDVSNVHDNELEFTRRRLVTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLL
KKITNNCIFIVIHRSTTSQTIKVSADDTPGAILQSFFTKMAKKKSLMDIPESQSEQDFVL
RVCGRDEYLVGETPIKNFQWVRQCLKNGEEIHLVLDTPPDPALDEVRKEEWPLVDDCTGV
TGYHEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNADLTVFVEANIQHGQQ
VLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPRGALLNLQIYCSKAPVLAGKTSAETPSS
ESKGKTQLLYYVNLLLIDHRFLLRHGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKEN
SMSISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDK
ELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLD
CNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIG
HFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTDQVQVIEMLQKVTLDIKSL
SAEKYDVSSQVISQLKQKLENLQNSNLPKSFRVPYDPGLKAGALVIEKCKVMASKKKPLW
LEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCIST
GDKIGMIEIVKEATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSC
AGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFL
FVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIR
DALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A3Q2Q4H1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Fundulus heteroclitus|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLINIKQQLFIEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIMSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLENFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCENVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVSLFDYMDILVSGKMALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
RFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSATDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCLNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPIVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEIHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMESLQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDRVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNHGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLMLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A1S3GL83|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dipodomys ordii|TrEMBL
MSPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHHAQYEPFFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRVKMRQFCEEAAVHRQQLGWEAWLQYSFPLQLEPSSRSWGA
GSPRTPNRTLLVNVKFEGSEESFTFQVSSKDKPVALMACALRKKATVFRQRLAERPEDYA
LRVNGKQEYLYGSHALCQFQYICSCLHSGRTPHLTMVHSSTILAMRDEQSNPTPQVQKPR
TKPPPIPAKKPSSVSLWSLEQAFCVELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSS
SEVSVSSEPVWQQRLEFDISVCDLPRMARLCFALYAVVEKTKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGEHCLYMWPSVPDEKGELLNPVGTVRSNPNTESAATLLICLPEVSP
HPVYYPALEKILELGRPGERMRATEEELQLREILERRGSGELYEHEKDLVWKLRHEVLER
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLR
KLTDDELSHYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGCTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMRQ
DAYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSNEEAGSAGNVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRGYCE
KAYSILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWMAHNVSKDNRQ
>A0A665V8J2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDTEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEAVDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A3Q3WVJ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mola mola|TrEMBL
MEKKQTQLSDDEHEVVQEVSQRRRKKAINSSSHSSMDQITVEFMLPTAARGGNNPETLLL
DVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRLSPDHCILLYQKKGSLCEIYDKHQVFQTL
DCIRYWRALKKDVGRIQLVPRPQPSEESLQYQCYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRCNELSNRDPKLYSMDPWVTCKLLPEHLLSKLQISNSHILVVIHIGTTSQTIKVSI
DDSPAQVLASFFTKTANRRVLLGIPDNMCEADFVLRVCGREEYLYGDKPLKNFNWIRQCL
KNGEEIHLVLEIPPDPVLDLVQKEDWAQVDDCTGAAGTHEQLTIDEKDHERVFTISMWDC
KRKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFTEEVLWNCWLEFN
INIKDLPKGARLNLQVNMEAQPTRIVQQEQATKSRLLYYVNLLLIDHRSLLRQGEFILHM
WKMPEKSEESSSSINVDKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDLGGDARTGS
VDTEGGQRGQREMPNHLKRQFAAILATDPLHPLSTEDKELLWHFRHECMRDPRAYPKLLA
SVKWGKQEDVLETHRLLERSSAWDNSGRDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDD
DVLRYLLQLVQAVKFEPYQKHRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCG
EAMLQDFRKQVEMTDALQKVTREIKAMSADKYDITAQVVFQLRQKLETLQSSGLPQSFRV
PYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADHTTLSKDAIGIIFKDGDDLRQDMLIL
QILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFKDE
ILYQWLRDKCGSEDKFQQRVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDF
GHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSSNFRKFQDVCVKAYLALRHHTN
LLIILFSMMLMTGMPQLTSKEDIEYIREALTVGCIEDEAQRHLLDQIEICREKGWMVQIN
WFVHLVLGIKQGVEKRSV
>H2TWY0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
MDGEQAQLSDEDSAIVTGDHSRRRRRRRKAVGSAPHSSMDQISVEFVLPAAARCKSGSDK
LLLDVAANWTVEQVKTQVWLRAVTLNICPDFYQRFSPDQCILLYQKKGSVCEIYDKHQVF
QTLDCVCYWRALKKEVGRIQLVLRPQPSEESLQYQRYLNYLMGYDVTDVSNVHDDELEFT
RRKLLTPRRLELVERDPKLYSMDPWVTCKNLPEHLLSKVSNGSILVVIHVSTVSQTIKVS
IDDSPAQVLTSFFAKTSNKRVLLGIPENLSETDFVLRVCGREEYLYGDKPLQNFNWVRQC
LKNGEEIHLVLETPPNPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDGKDHERVFTISMWD
CNRKFRVKVLGIDIPSLPKIPDFLVFVEASIFHGQQLLAQERTSSKTFTEEVLWNCWLEF
NIKIKDLPKGARLSLQVVCRKQPQTLNSKGGSAQQDSPAAAAAGGHDGKTKSRLLYYVNL
LLVDHRSLLRQGEFILHMWKMPEKSDESSSSINADKLTSATNPDRASSMAVAILLDKYCY
PVVLPKSRAASREARGGVEEAQGGERGQREMPNHLRKQFAVIVRTDPLHPLSPEDKELLW
HFRHECTRDPRAYPKLLSSVSWGKQEDVLETHRLLERSSAWDSSGLDVGLAMQLLDCHFS
DAQVRSLAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSSLVRFLLKRALRSKRIGHFLF
WFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRKQVETTEALQKVTREIKTVSADK
YDITAQVVFQLRQKLEALQSSGLPEDFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFK
RADSTTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRI
GMIEIVKDATTIANIQQSVVGSTGAFKDEILCQWLRDKCVNEDKFQQAVERFLHSCGGYC
VATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMG
TSGKKSSPNFQKFQNVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALT
VGRSEDEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRSA
>A0A8D0LD41|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphenodon punctatus|TrEMBL
MELGNYEQTVVMREENKRRRRRMKTHCTTSNLSSMDLIPIEFILPTSNKHTKVPEKLLLE
IAGNCTVEQMKAQIWMRALEMSQTTDFYHKFTPDQFLLQYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGKIHVIQKQKPSEEVEEFQNQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTTRMIEVACRDPKLYSMHPWITSKPLPAYLLKKISNNNIFITVHRGTTSQKIKVSIDDT
PDMILQSFFTKIANKKSLMDIPEDRSELDFVLRVCGRDEYITGDVPIKDFYWIRQCLKNG
EEIHLVLDNPPDPNQDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTTSKPFTEEVLWNTWLEFDIKI
KDLPKGALLNLQIYCGKAQAALATKTNLQTHDSPNSDSKCKTQLLYYVNLLLIDHRFLLR
SGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISVVLDKYCHPIALPKHKITS
DPQGDRTRAEMPNQLRKQLEEIIATDPLNPLTPEDKELLWHFRYESIRHPEAYPKLLSSV
KWGQQEIVAKTYQLLAKREIWDRSTLDVGLTMHLLDCNFSDENVRAMAVQKLDSLEDDDV
LHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVI
LEAYLRGCWKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLKQKLEKLQN
NKLPENFRVPYDPGLHAGALVIEKCKVIASKKKPLWLEFKCADPTALSNETIGIIFKHGD
DLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDAITIAKIQQSTV
GNTGAFKDEILNQWLKERCVIEEKFQTAVERFVYSCAGYCVATFVLGIGDRHNDNIMITE
SGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVIGTSGKKTSLHFQKFQAVCVRA
YLSLRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKTEEDAKKYFLDQIEICR
DKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L0BK57|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Spizaetus tyrannus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLPSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIESLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
RLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A091R8V2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Merops nubicus|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVKDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAVEA
AINRKSSNLPLPLPPKKTKTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYTVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLRTGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPVHYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPGVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEDAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A674GXV2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCASSSFSSMELISIEFILPTSNKHTKAPETMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQELQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKIINNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
DEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSSLDVGLTMQLLDCNFSDENVRAMAVQKLESLDDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGH
ILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAYLALRHHTNLL
IILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDKGWTVQFNWF
LHLVLGIKQGVEKHSA
>A0A8C5A8V5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MVPKPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLANIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDEARRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFELVKDPEVQDFRRSILSVCREAMEEREAGGAPSLALYVYPPNVESSPELPQH
IYYKLDKGRLMVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKTRSMHLSAQQLR
LCVLEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCITVGRLPHLMLVSKESLYSQLPES
GFVMPSYSRRTPQPSPCPGGDPTSPPRSLWAFNNLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYMADIPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDTMVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFC
WFNQTVVFPDDQQIEEHANWTISRELGLTYCYYFVSAAEVEQLQSLCSKDPLYELSEQEK
DFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKDWPLMQPESALELLDCNFPE
PVVREFALRCLLQGLSDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFF
WHLKSEMHNKTVSRRFGLLLEAFCRSCGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQ
KTQMKFLVEHMSRPDYMDALQGFISPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDI
MSELLFTNNQVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLI
EVVRNSYTIMQIQCKAGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTRSCAGYCVAT
FILGIGDRHNSNIMVKDNGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLLVISKGS
QECTKTKEFDRFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLAL
EKTQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A8C4ZXY1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMLLTLECLREATLITIKHELFREARKYPLHH
LLQEQTSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILSVCKDSVELRDVSGPHSRALYVYPPSVESGQELPKH
IHSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMRLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYSQLPAD
AFVMPSYSRRISTATAYMNGELAAKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLGWGNINLFDYTHTLVANKMALNLWPVPRGMEDLLNPIGVTGSNPNKETPCLELEFDHF
SCLVKYPEMSSVEEHANWSVSREMGFSYNLSGQSSRMARDIALTEGDVEQLRQLSHRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIQPEHTME
LLDCNYPDPMVRCFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLIHLTDLLK
QEKKDETQKVQMRFLVDQMKRPDYMDALQSFTSPLNPAHQLGNIRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNRGETYDLAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A452RJY4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus americanus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRQEYLYGGYPLCQFQYICGCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKVSPLAVQGLGGSRGCGQLQLREILERRGSGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLRAPGPELPVLSALEAAGLQLPRPHVASFATSTLR
KDDELFRYLLQLVQVLKYESYLDCELAKFLLARALANRKIGHFLFWHLRSEMHVPSVALR
FGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHVCMRQET
YLEALSNVQSPLDPSTLLAEVCVEQCTFMDSKMKPLWLVYSSEEAGSDGSVGIIFKNGDD
LRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSN
MAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRE
NGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERA
YTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEAL
RESWKTKVNWLAHNVSKDNRQ
>A0A8C4YU63|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MPPGNYGMEEEWEAEGNADIMVDFLLPTGIFLEFPVSRNDTIADIKKLVWRRASSEPLFN
ALGDPASYVFVCISSAAERLELEAEHRRLADVRPFACFLQLVAREGDRAEKLANAQISLL
IGKGINEFEAQKNHEVSEFRARLRAFCEEKALQQQALPWFQWMECNFPCDLEPCRALPSR
GGGAKAPKKIFINIQFEGSDESFMLQQDPQEPPLALIRSALKKKATVFRWVRQEAEDYTL
RVNGRWDFLYGDHPMCQFKYIFSCLRDGQNPQLTMVYHSTIRAYQEDQGSAWRQGSKSST
SASKPPPLPLKKQNTTLLWTISEPLCIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKLV
TSSEVAVGSDPVWNQRLEFDINVADLPRMSRLCIALYAVVEKAKKPRGTKKKSKRADCPI
AWVNTMVFDYKDQLKTGEFLLSMWPSIPDDKSELLNPMGTVEKNTNVDSAAALLIHFPSV
RPQPLYYPPHDKISCMEANGERPSPTKEEHVRLKEIMDNKNHTEFFEDEKELLWKLRGAV
QSLYPESLSKLLVITKWNKREDVAQMVGLLRAWPELSGLHALELLDYSFPDPSVRAFTVK
CLKKLGDRELMQYLIQLVQVLKYESYLDCDLTSFLLERALSNKRIGHFLFWHLRSEMHVS
SVSLRFGLILEAYCRGNIHHIRSLTKQNEALGKLKALSDIVKSGSQKMSADDLKLCIKQD
SYMEALSDLLSPLNPSIILSEICVEKCKYMDSKMKPLWLMYKNQWVPGDLMGIIFKNGDD
LRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRDNSN
SAATAAFNKDALLNWLKSKNPEHKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRDYCERA
YKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKTEEEALKSFKVKFNEAL
RESWKTKVNWMMHSLAKDKRP
>A0A8J4U8Z6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Clarias magur|TrEMBL
MEQNASDDESPVVFRGENRRRRRKMKAFTSSSSVAMDHLALEFVLPTTNKTTKSPDTLQL
DVIGNWTVEQVKAQLWLKAVTTNVCPEFYQKYSPDHCILLYQKKGSWCEIYDKHQVFQTL
DCVRYWKALKKDVGKIHLVQRPHPSEGSVQYQKFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELVDRDPKLYSTDPWVTNKPLPDYLLSKITNNHILIVIHRDTSSQTIKVSIDD
TPFQVLQSFFLKTTNKRALLGIPEDVSESDFVLRVCGREEYIFGNYPIKDFHWIRQCLKS
GEEIHLVLESPPEPEQDVVQKEDWSQVDDCTGVAGTHEQLTINEKDHEKVFTISLWDCTR
KFRVKILGIDIPVLPRNSDLIVFVEASIFHGQQLLAQERTSPKPFTEEVLWNTWLDFNIK
IKDLPKGARLNLQVSCGKAQTQTAKDSVSHDGKNKSRLLYYVNLLVVDHRSLLRQGEFIL
HMWKMPEKSEDNSSVNADKLTSATNPDKTSSMAIAVLLDKYCYPVALPKSRDCRDASELE
GERGRREMPNHLRKQFDQIVATDPLHPLSTEDKELLWHFKQECVRHPSAYPKFLGSVKWG
KQEAVMSTHHLLERSTTWDRSPLDVGLAMQLLDCHFSDAIVRTMAVRKLETLGDDDVLRY
LLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEA
YLRGCGDAMLQDFRKQVEITEALQKVTREVKAISAEKYDVSAQVIFQLRQKLENLQGLPE
SFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQD
MLILQILLIMESIWETESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGA
FKDEILNQWLRDKCVNEDKYQQAVERFVYSCGGYCVATYVLGIGDRHNDNIMITESGNLF
HIDFGHILGNYKSFLGITKERVPFVLTPDFLYVMGTTGKKTSPNFLMFQNICVKAYLALR
HHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGCTEDVAQRHFLDQIEICRDKGWT
VQFNWFLHLVLGIKQGVEKRSA
>A0A8C1C9W5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MWFVLHGGIDDEPPVVRREENKRRRRKMKAFTSSSAVSTDHIAVEFVLPTTNKNSKYPDT
LHLDVTGNWTVEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVF
QTLDCIRYWKALRKEVGKIHLVIRQQPNEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFT
RRKLLTPRKIELSDRDPKLYSMDPWITPKPLPEYLLSKISNNHILVVIHKDTTSQTIKVS
IDDTPVQVLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAISDFHWIRQC
LKNGEEIHLVLEHPPDPELDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWD
CNRKFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEF
NIKIKDLPKGARLSLQVSCGKAQTQTSKENECKNKTRLLYYVNLLMVDHRSLLRQGEFIL
HMWKMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEG
ERGQREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGK
QEAVAITHCLLERSTVWDRSSHDVGLALQLLDCHFSDENVRTLAVRKLETLEDDDVLRYL
LQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAY
LRGCGEAMLQDLRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLP
DSFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSRDTIGIIFKDGDDLRQ
DMLILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTG
AFKDEILSQWLSEKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFMGISKERVPFVLTPDFLYVMCTTGKKSSPYFLQFQNVCLKAYLAL
RHHTNLLIILFSMMLMTGMPQLSSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGW
TVQFNWFLHLVLGIKQGVEKRSA
>A0A8C1JJR5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MEHQASDDEPPVVRREENKRRRRKMKAFTSTSAVSTDNIAVDFVLPTTNKNSRNPDTLHI
DVTGNWTVEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVVRTQPNEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELADRDPKLYSMDPWITPKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFAKIKKKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKN
GEEIHLVLEHPPDPELDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLLVDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERG
QREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEA
VMITHHLLERCTVWDRSLLDVGLAIQLLDCHFSDEKVRTMAVRKLETLEDDDVLRYLLQL
VQAVKFEPYHDSALARFLLKRALRSQRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRG
CGEAMLQDLRKQVEMTEALQKVTREIKLMSAEKYDVSQQVVLQLRQKLEGLQTSGLPDSF
KVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDML
ILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFK
DEILSQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFMGISKERVPFVLTPDFLYVMSTTGKKSSPHFLQFQNVCLKAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGCSEDEAKQHFLEQIEICRDKGWTVQ
FNWFLHLVLGIKQGVEKRSA
>A0A8C1J8P0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVAQS
GKSRSVKKILVNVKFEGSEETFVLQQDPQDLPMLLKRNALRKKSTVFRAAKQEKPEDYTL
QVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQMSRTRA
PSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVI
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGMNGEKVVTTKEEHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQ
RYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHVRSFTIRCL
RNLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRSEMHVPSV
SLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIK
QDTYMEALSDVVSPLNPSIVLCELCTDKCKFMDSKMKPLWLMYKNKYDHVGIIFKNGDDL
RQDMLTLQMIQLMDVLWKTEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECC
EQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFN
EALRESWKTKVNWMMHTFAKDNR
>A0A8C6P1D4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius furzeri|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLDCLRETPLISIKQQLFVEARKFPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDSEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPHLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKTRSMHLSPQQLR
LCVQEYQGQYILKGAAALCHLHQRQHPGH
>A0A7L0GHQ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Herpetotheres cachinnans|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLHIPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
SKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAASEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2K6FPJ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Propithecus coquereli|TrEMBL
MELENYEQPVVLREDNGRRRRRMKPRSAVASLSPMELIPIEFVLPTSQRHSKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQIHLVQRRAPSEETQAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLSKKIANNCIFIIIHRSTTSQTIKVSAEDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDDVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKVSADTSGSESKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPSPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGFNKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7K9S9N8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sterrhoptilus dennistouni|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSNFSSMELISIEFILPTSNKHTKAPEILLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKHHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIPSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVAKKCKVMASKKKPLWLEFKCADSTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVHSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7J7T131|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pipistrellus kuhlii|TrEMBL
MPPGVDCPMEFWANEENQSVAVDFLLPTGVYLNFPVSRNASLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQLCEEAAARRQQLGWEAWLQYSFPLQLEPAARAWGP
GLRAPGRALLVNVKFEGSEESFTFQVSTKDLPLALMACALRKKATVFRQPLVEQPEDYTL
QVNGKQEFLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKSRT
KPPPIPMKKPSSLSLWALERPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSS
EVSVCSEPVWKQRLEFDIHVCDLPRMARLCFALYAVIEKAKKARSTKKKAKKADCPIAWA
NLTLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVCNNPNTESAAALVICLPEVAPH
PVYYPALDKILELGRHGEHGRATEEELQLREILERRGAGELYEHEKDLVWKLRHEVQERF
PEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSLRK
LTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVSL
RFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPQTKELMHLCMRQE
TYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVVYSNEEAGGDGSVGIIFKNGD
DLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKS
NMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIR
ENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCER
AYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEA
LRESWKTKVNWLAHNVSKDNRQ
>A0A7K8DSI9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leucopsar rothschildi|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKYKTQLLYYVNLLLIDHRFLLRS
GDYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESVKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQEAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A668UD72|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRSKMFRISEERMQQIQMMTFSEWVQACYSPQLEPA
AVTAITAGVNDAPVDLKVIIHFDQSQDSASLKVSLSCTPNELMEQALRKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKETPHLTLVHTSAVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRRAPTVSPNIMHDSVNNIISIFMSVSANRLMLFSRTETEGVQV
RAGLFHGTELLCKPAVSNESSGRSEHTWKDNTLEFEISVCDLPRMTRLCFAIYAVMDKVK
KQKSTKNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEM
LNPIGTIQTNPYTENATALHIHFPEYSSHPIVFPPFDKILEKAAEMVSADCVSIGRGVKK
FYMELKEIMERDPVSQLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQA
LLQIWPKLSPRDALELLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYD
CALTHFLLERAQRNRQIGHFLFWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQV
EALSKLKSVNELIKLGTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVL
LSDINVEKCRYMDSKMKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLW
KEANLDLRIVPYGCLATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKE
RNSGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKS
KFGIKRERVPFILTHDFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALM
LTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKD
NRS
>A0A668VNB0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKSKNIKKIFINVKFEASDQDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQVNGRWD
FIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTITKYQEEQGRMCSQVYKMLKSSASKPH
VLPPSNHYCVSVVPLQLVVQAGLFHGSELLCKVVTSSEVTVSSEPLWNQKLEFDINVADL
PRMSRLCFALYGVIEKTKKPRGTKKKNKKAVSVSITRGVFGDCPIAWVNTMVFDYKDQLK
TGEFHLSTWPDLLNPMGTVEKNPNVDSAAELLIHFPNIRPHPLYYPPLEKVPSPKRLHKT
YFKLKEIMDNKNYTEFFEDEKELLWKLRTEVRDHYPESLSKLLLITKWNKREDVVQMVNL
LRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLRKLRYTHICFRSLHDDELLHYLIQLVQ
VLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASVGLRFGLILEAYCRGNIH
HIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESYLEALSDLLSPLNPSIIL
SEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWK
KEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSK
NPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRK
LGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMK
AAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDN
RP
>A0A668VN96|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKNIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRVFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKSKNIKKIFINVKFEASDESFMLQQDPHDQPLALMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTITKYQEEQGRMCSQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKICDMERNGDLSLANKEEYFKLKEIMDNKNYTEFFEDEKELLWKLRTEVRD
HYPESLSKLLLITKWNKREDVVQVRMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIR
CLRKLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVA
SVGLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQE
SYLEALSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDD
LRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSN
SAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERA
YKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A7L3ZFF9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Circaetus pectoralis|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLPSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIESLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
RLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C9WY60|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MPPGKYGMQEEGDQEIMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNARSEALFSALGD
PDAYVFTCINQTAEREELEEESRRISDVRPFMGVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFEAQKNHEVNEFRAKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPECGSVK
SKNTKKIFINVKFEACDESFMLQQDPQDFPVALMKSALKKKATVFRSVRQEPEDYTLQVN
GRWEFIYGNHPMCQFKYMFLCLRNSQIPHLTMVHHTTISKYQEEQGRMCSQGYKTRSLSR
PPPLPLKKNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTTSEV
TVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVNT
MVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPL
YYPPLDKVRILKRLFFMSTNLQFNFYNKIMDNKNHTEFFEDEKDLLWKLRTEVRDHYHES
LSKLLLITKWNRREDAVQMMSLLRTWRDLPAIHALELLDYSFPDPVVRSFTIRCLRKLSD
DELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLRSEIHVASVSLRFG
LILEAYCRGNIHHIKLLSKQNEALGKMKALSDFVKSGSQKMTADDLKLCIRQESYLEALS
DLLSPLNPSIILTEICADKCRFMDSKMKPIWLMYNPCTQEDMVGIIFKNGDDLRQDMLTL
QMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFN
KDALLNWLKSKNPEDKLDRAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHID
FGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNG
MLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKV
NWMMHSLAKDNRP
>A0A7L0K2S2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chauna torquata|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKQQQLSWTAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPDEFPITLMSYAIKKQATVFRHETMENPEDYT
LQVNGKCEYLYGNYPLCQFQYIRSCLHRGLTPHLTMVHSSSIIAMRDEQINCIANTPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRHD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K8T375|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nyctibius bracteatus|TrEMBL
MELRDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSE
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPGSFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K7S9B7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nesospiza acunhae|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPTKNIFVNIRFQSGGESFMFQISPWEFPITLIGYAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSSLQRGLTPHLTMVHSSAIIAMRDEQTNCITSTPKAASK
PPPLPRKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKALMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A4W3H4Y5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPGMQYHQDLWSEDENPDVEVEFLLPTGIYLNFYVPRSSTISYIKKLLWQQAQQQPLFH
TLNEPDAYVFTCINHTAEREELEDERRRLCDVRPFLPVLKLVAREGDRAEKLINSQISLL
IGKGLHEFDCMQDYEVAEFRLKMRQFCEDKESERLRMSWQDWMEYSFPRELEPIQEAPDN
NMIRTLSNRNIVINVKFQYNEESFSFQISPQSHPGTLMQMAVKKKATVFRHKTVEHTEDY
TLQVNGTEEYIYGNYPLGQFKHIWNCMYSSSTPHLTMVHSSTINSLKGEQSNSIAQVPKS
RTYSKPPPLPIKKFHPQNTQSLHSAVKPCIRASFHRCFPFSPPQLVVQAGLFHGSEMLCK
TVSSHEVSVCSEPAWDQALEFDIHFSDLPRMTRLCFALYGVIDKAKKARSTKKKSKKADC
PIAWVNTMVFDYKDQLKTGDVWLHMWPSIPDEKGELLNPMGTVQGNPNTDSAAALYVRFR
NMGSYPIYYPSFDKVCTELIPRGFEFSAQKEAIQHLKEIMERKSCTEFFEDEKDLVWKLR
WESRDHYSDALAKLLSITKWNKHEDVAQMIYLLQSWPELPALHALELLDYSYPERYVRSF
AINCLKNLSEEELFQYLLQLVQVLKYEPYLDSELTKFLLNRALANKKIGHFLFWHLRSEM
HVPAVSLRFGLILEAYCRGNNYHMKSLMKQCESLKKMKALNDFVKSSSQKTTKPKTKEAL
HLFMRQEAYMEALSNLHSSLNPSSLLTDLWVDKCKFMDSKMKPLWIVYKNEKYDGDPMGV
MFKNGDDLRQDMLTIQMIQLMDVLWKRQGLDYRMIPYACLSTGDKTGLIEVVSRSETIAN
IQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMIRENGQLFHIDFGHFLGNFKSKFGINRERVPFILTHDFVHVIQQGKTSNSEKFERF
RKYCEHAYMILRKHCPLFINLFALMRAAGLPELSSSKDIQYLKDSLALGKTEEEALKHFK
MKFDEALRESWKTKVNWMAHNVAKDNRS
>A0A7L0UUE4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptocoma aspasia|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWRQAQHEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GALQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETLQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAT
CKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGSEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
ANVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQHPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7J6C9X8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Onychostoma macrolepis|TrEMBL
MPPAKTDQLDLWAESGLDGDVQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSMQLETGSLE
NLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIGTRSDY
VLRVSSRLEFLFEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAMFEKEISTIGSVLAR
KTSNPPLPLPPKKRPPTQLHTCVWKVHSLFRINLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHVWNKTLEFDIPVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGANDSMTMGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSP
RDALELLDFNYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLMER
AQSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVN
ELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLQSPLNPNILLAGVHVERCKYMDS
KMKPLWIVYNNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGC
LATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALEKAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
HDFIHVIQQGKTGNTEKFGNFRQYCEDAYLILRKNGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A8C6UP15|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neogobius melanostomus|TrEMBL
MSPGKYGMQEEWEKEEAWDQGIMMDFLLPTGIFLKFPVSRNDTIKTIKKMVWKNAKSEAL
FSALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQIS
LLIGKGLHEFEAQKNHEVNEFRTKMRAFCEEKALERQLLPWRLWMEYSFPCDLEPCCSPH
EEGNNKKKNTKIFVNIKFEASEESFMLQQDPQDLPMALVKSALKKKATVFRSVRQEPEDY
TLQVNGRWDFIYGDHPLCQFKYMFSCLRNGQAPQLTMVHHSTISKYQEEQGRMSNQLFQS
RSLSRPPPLPLKKLVVQAGLFHGSELLCKVVTSSEVTVRSEPLWDQKLEFDISVSDLPRM
SRLCFALYAVIEKTKKPRGTKKKNKRADCPIAWVNTMVFDYKDQLKTGEFLLSAWPSVPG
TNRLILSKSVSTASSTAPVSACSGLKNPVWHVALAHILSVRDFLEFQLLRLKEIMDNKNY
TEFFEDEKELLWKLRYEVRERYPESLSKLLLITKWNKREEVVLMVSLLRNWPDLPAIQAL
ELLDYSFPDPSVRSFTIRCLKKLSDPELLQCLIQLVQVLKYESYLDCDLTTFLLERALSN
QRIGHFLFWHLRSEIHVSSVGLRFGLILEAYCRGNIHHIKLLTKQNEALTKMKALSDIVK
SGSHKMTVDDLKLCIRQESYMEALSDLLSPLNPSIILTQICADKCRFMDSKMKPLWMMYR
NPCFQGEMVGIIFKNGDDLRQDMLTLQMIHLMENLWKKEGLDLRMIPYGCLSTGNKMGLI
EVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPGDRLEQAIEEFTLSCAGYCVA
TYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQG
RTNNSEKFERFREYCEWAYKILCHNGILFVNLFAMMKAAGLPELTSSKDIQYLKDSLALG
KSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A2Y9MZW2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Delphinapterus leucas|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A1U7UHD6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carlito syrichta|TrEMBL
MCFSVTMPPAMADVLDIWAVDSQIACDGSIPVDFLLPTGIYIQLEVPREATIAYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRQFSEEKIQSLVGLSWMDWLKHTYPPEH
EPSILENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMNPLKINELAIQKRLTIHGKEED
ASPCDYVLQVSGRVEYVFGDHPLIQFQYIRTCVINRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKTRVISHIWENNNPFQVVLVKGNKLNTEEAVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCLAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHVKFPESKKQPYCYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVDCLRQMSDEELAQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYTNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLVLRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6I8RLG9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus tropicalis|TrEMBL
MELDSYEQPVVLRDENQRRRRRMRPHSATSNMFPMEQIPIEFILPTSNRCSKVQETMLLE
VAGNCSVEQMKAQIWMHAIEKSHNSDFYQRLTPDQFLLQYQKKGQWYEIYDKHQVIQTLD
CIMYWKVLQKTVGKIHIVQKEKIPEEMIEYQKTLNYLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIELSRRDARLYSMDPWVTCKSLPEYLCQRIISNSIFIIIHKGMTSHTIRVSIDDT
PDVILHSFFTKMAKKKSLLDISEENSELDFVLRVCGRDEYIIGNAPIKDFHWIRQCIKNG
QEIHLVLEKPPDPLMDEVQKEQWPLVDDCTGVTGYHEQLTIEGKDHEKIFTISLWDCNRK
FRVKIIGIDIPVLPKNTELIAFVEANIQHGQQVLSQRRTTCKPFTEEVLWNSWLEFDIKI
KDLPKGALLNLQIFCGKAPTASNKSIVQSPESTASDSKCKNQLLYYVNLLLIDHRFLLRQ
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKETSMAISISLDKYCHPVALPKHKLVCD
PELERPRTEMPNQLRKQLEEIIATDPLHPLTPEDKELLWHFRSEIVKHPEAYPKLLSSVK
WGQQEMVAKTYQLLSKREAWDDCSLDVGLTIQLLDCNFSDENVRAMAVQKLESLQDDDVL
HYLLQLVQAVKFEPYHDSALSRFLLKRALQSKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLDDFTRQVQVTEILHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQNS
KLPDKLPDSFRVPYDPGLRAGSLVVEKCKVMASKKKPLWLEFKCSDTTALSNETIGIIFK
HGDDLRQDMLILQILRIMGSIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAQIQQ
STVGNTGAFKDEVLSQWLKEKCPIEEKFSAAVERFVYSCAGYCVATFVLGIGDRHNDNIM
VTESGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSQYFNKFQLLL
LGENCTGLWKKTVLALCRHFTFRVVFQASLVRIPVCACTVE
>A0A6I8PVL1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus tropicalis|TrEMBL
MKKETLLCRGNMLASGMELDSYEQPVVLRDENQRRRRRMRPHSATSNMFPMEQIPIEFIL
PTSNRCSKVQETMLLEVAGNCSVEQMKAQIWMHAIEKSHNSDFYQRLTPDQFLLQYQKKG
QWYEIYDKHQVIQTLDCIMYWKVLQKTVGKIHIVQKEKIPEEMIEYQKTLNYLIGYDVTD
VSNVHDDELEFTRRRLVTPRMIELSRRDARLYSMDPWVTCKSLPEYLCQRIISNSIFIII
HKGMTSHTIRVSIDDTPDVILHSFFTKMAKKKSLLDISEENSELDFVLRVCGRDEYIIGN
APIKDFHWIRQCIKNGQEIHLVLEKPPDPLMDEVQKEQWPLVDDCTGVTGYHEQLTIEGK
DHEKIFTISLWDCNRKFRVKIIGIDIPVLPKNTELIAFVEANIQHGQQVLSQRRTTCKPF
TEEVLWNSWLEFDIKIKDLPKGALLNLQIFCGKAPTASNKSIVQSPESTASDSKCKNQLL
YYVNLLLIDHRFLLRQGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKETSMAISISLD
KYCHPVALPKHKLVCDPELERPRTEMPNQLRKQLEEIIATDPLHPLTPEDKELLWHFRSE
IVKHPEAYPKLLSSVKWGQQEMVAKTYQLLSKREAWDDCSLDVGLTIQLLDCNFSDENVR
AMAVQKLESLQDDDVLHYLLQLVQAVKFEPYHDSALSRFLLKRALQSKRIGHFLFWFLRS
EIAQSMHYQQRFAVILEAYLRGCGKAMLDDFTRQVQVTEILHKVTMEIKSVSAEKYDVTS
QVITQLRQKLEKLQNSKLPDKLPDSFRVPYDPGLRAGSLVILRIMGSIWEAESLDLCLLP
YGCISTGNKIGMIEIVKDATTIAQIQQSTVGNTGAFKDEVLSQWLKEKCPIEEKFSAAVE
RFVYSCAGYCVATFVLGIGDRHNDNIMVTESGNLFHIDFGHILGNYKSFLGINKERVPFV
LTPDFLYVMGTSGKKTSQYFNKFQDVCVKAYLALRHHTNLMIILFSMMLMTVCAEAYNPD
EEDDDTETKVIYPKTDDQRNRLQEACKDILLFKSLDQEQMSQVLDAMFEKLVKCGEHVID
QGDDGDNFYVIDRGTYDIFVKSDGVVRCVGAYDNRGSFGELALMYNTPRAATIVATSVGS
IWGLDRATFRRIIVKNNAKKKRMYENFIESLPFLKSLEFSERLKVVDVIGTKTYYDGEQI
IAQGDGADSFYIVESGEVRINMKSKSKPDAETNEAVEIARCTRGQYFGELALVTNKPRAA
SAYAVGNVKCLVMDVQAFERLLGPCMEIMKRNIANYEEQLVALFGTNMDITDPST
>A0A803JJ37|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus tropicalis|TrEMBL
MELDSYEQPVVLRDENQRRRRRMRPHSATSNMFPMEQIPIEFILPTSNRCSKVQETMLLE
VAGNCSVEQMKAQIWMHAIEKSHNSDFYQRLTPDQFLLQYQKKGQWYEIYDKHQVIQTLD
CIMYWKVLQKTVGKIHIVQKEKIPEEMIEYQKTLNYLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIELSRRDARLYSMDPWVTCKSLPEYLCQRIISNSIFIIIHKGMTSHTIRVSIDDT
PDVILHSFFTKMAKKKSLLDISEENSELDFVLRVCGRDEYIIGNAPIKDFHWIRQCIKNG
QEIHLVLEKPPDPLMDEVQKEQWPLVDDCTGVTGYHEQLTIEGKDHEKIFTISLWDCNRK
FRVKIIGIDIPVLPKNTELIAFVEANIQHGQQVLSQRRTTCKPFTEEVLWNSWLEFDIKI
KDLPKGALLNLQIFCGKAPTASNKSIVQSPESTASDSKCKNQLLYYVNLLLIDHRFLLRQ
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKETSMAISISLDKYCHPVALPKHKLVCD
PELERPRTEMPNQLRKQLEEIIATDPLHPLTPEDKELLWHFRSEIVKHPEAYPKLLSSVK
WGQQEMVAKTYQLLSKREAWDDCSLDVGLTIQLLDCNFSDENVRAMAVQKLESLQDDDVL
HYLLQLVQAVKFEPYHDSALSRFLLKRALQSKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLDDFTRQVQVTEILHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQNS
KLPDKLPDSFRVPYDPGLRAGSLVVEKCKVMASKKKPLWLEFKCSDTTALSNETIGIIFK
HGDDLRQDMLILQILRIMGSIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAQIQQ
STVGNTGAFKDEVLSQWLKEKCPIEEKFSAAVERFVYSCAGYCVATFVLGIGDRHNDNIM
VTESGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSQYFNKFQVCL
N
>A0A8C9FD10|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pavo cristatus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELITIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAIEVSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDLFPLVLSLLDCRALHMLLTRLLCIFQAVKFEPYH
DSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGKAMLHDFM
KQVQVIELLHKVTMEIKSVSAEKYDVTSQGLCNACLPLYFPAFFFFPSDFLKRVFIKIPV
SCSDLGLSARDMAIINSKRCKIWERDIPVLPTCSDQCVLGHKVLGSKVIPVLVTGKCLGW
YLRCSCFYRPCLGNLTVPSFYKGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVM
GTSGKKTSLHFHKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDAL
TVGKSEEDAKKHFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C4KIM0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dromaius novaehollandiae|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWQHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRIKMRQFCEERAAKRQQLSWAAWMEYNFPLQLEPLAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHQGLTPHLTMVHSSSIIAMRDEQTNCIANAPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVHCNPNTESAAALVICFPSITS
HPVYYPSFEQLLELGRNGEQPRAXLEDPEEKLQLKEILERRSHTELYEDEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDGELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVEQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALAKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2K6P5T5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhinopithecus roxellana|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVSQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A2U4BSH5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tursiops truncatus|TrEMBL
MELENHEQHVVLREDNRRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLSPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRLAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VSPRMAEVAGRDTKLYAMHPWVTSKPLPEYLLKKITNNYIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIRNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKAEDHGSINADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTMDIKSLSAEKYDVSSQVISQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSRHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A6P3HC26|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bison bison bison|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASMSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A8C8J4T8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRVKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQLSKS
RSLSKPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVV
TSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIHFPNI
RPHPLYYPHFDKPTSYICNHYTCNHLLKEIVDNKNYTEFFEDEKELLWKLRGVVRERYPE
SLSKLLLITKWNKHEDVAQMVTFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLR
DEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRF
GLILEAYCRGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAY
MEALSYLLSPLNPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDTVGIIFKNGDDLR
QDMLTLQMIQLMEILWKKEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMI
KETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCE
QAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNE
ALRESWKTKVNWMMHSLAKDSRL
>A0A6P5K5K5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phascolarctos cinereus|TrEMBL
MDLEDQEPVVLREDNRGRRRRMKPQSAGISSSSMELIPIEFVLPTSHQNTKVSETVILEA
AGSCNVEQMKAQVWMQAMETSMAMEFYHQSSPEQFLLLYQKKGQWYEIYDKYQLIQTLDC
VKYWKALHKNMGQIRVVQRQLPTEETREFQQQLNDLIGYDVTNMSNVHDDELEFTRRRLV
TPRIKEVAVRDPKLYAMHPWVTSKPLPTYLSKKIVNNCILIVIHRGTTSQTIKVSADDTP
GTILQSFFTKMAKKKSLMDIPESQSELDFVLRVCGRDEYIVGETPIKNFQWIRHCLKNGE
EIHLVLDSPPDPGQDEVRKEEWPLVDDCTGVTGYHEQLTINGKNHEKVFTVSLWDCDRRF
RVKIRGIDIPVLPRNTELTVFVEANIQHGQQVLCQRRTTSKPFTEEVLWNVWLEFDIKIK
DLPKGALLNLQIYCGKAPAQSSKAAGSHESSGFEAKGKTQLLYYVNLLLIDHRFLLRHGE
YVLHMWKISGKGEDQGSINADKLTSATNPDKDNSMSISILLDNYCHPIALPKHRPTPDPE
GDRVRGEMPNQLRKQLEEIIATDPLNPLTAKDKELLWHFRYESLKHPKAYPKLFSSVKWG
QQEIVAKTYQLLARREAWDRSDLDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHY
LLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEA
YLRGCGMAMLEDFTKQVQVIRMLQKVTIDIKSLSAEKYDVTSQVISQLKQKLENLQNSNL
PKSFRVPYDPGLRAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLR
QDMLILQILRIMGSIWEAESLDLCLQPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNT
GAFKDEVLNHWLKEKCPIEEKFQAAVEKFVYSCAGYCVATFVLGIGDRHNDNIMITETGN
LFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDICVKAYLA
LRQHTNLLIILFSMMLMTGMPQLTSKEDIDYIRDALTVGKNEEEAKKYFLDQIEVCRDKG
WTVQFNWFLHLVLGIKQGEKHSA
>A0A6P6J692|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Carassius auratus|TrEMBL
MPPGVYGMQDVWEREGRQQIDMEFLLPTGIYLKFPVSASDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVQPFMPILRLVAREGDRVEKLITTQINLL
IGKGHHEFDSQKNHEMNEFRTKMRTFCEEHAQVRQMLPWEPWMEFNFPCDLEPCSVVAKS
HSVKKILVNVKFEGSEETFVLQQDPHDLPIALKRSALRKKSTVFRAARQEKPEDYTLQVN
GRLEFIYGEYPLCQFKYIFSCLHGGITPHLTMVHHSAIIKYQEEQGGLSNQVSRTRAQSK
PPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVISNE
VGVCSEPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAWVNT
MVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPL
YYPPIEKLNELGMNGEKVVATKEENLKLREIVDNKNYTEFFEDEKELLWKLRVEVRRRYP
ESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHVRSFTIRCLSNL
RDDELFQYLLQLVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRSEMHVPSVSLR
FGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRVQTTEDMKVCIKQDT
YMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKNKYDHVGIIFKNGDDLRQD
MLTLQMIELMDVLWKKEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAAT
AAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQL
FHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFREYCEQAYKIL
CRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESW
KTKVNWMMHTFAKDNR
>Q5F4A2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gallus gallus|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHTY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
NFQDKLYSGNLVVAIHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEIDPAD
YVLQVSGRLEYVFGDHPLIQFQYIHNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEVAIN
RKSSNLPLPLPPKKTRATTSVWDICSPFKIVLLKGNKLNTEENAKVHVRAGIFHGTELLC
KTIVSTEISGRSDHAWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKSMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGEFVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCKYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6D2YAW0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pongo abelii|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSILVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A4W2F3L0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos indicus x Bos taurus|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASMSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLRDFTQQVQVIDML
QKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLPQSFRVPYDPGLKAGALVIEKCK
VMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDL
CLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLSHWLKEKCPIEEKFQ
AAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKER
VPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQL
TSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A8C5JTM2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Junco hyemalis|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSSLPLPLPPKKRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLCK
TIVSTEISGRSEHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKYQ
TIRKAGKVHYPVAWVNTMVFDYKGHLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMERD
PLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPRE
ALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERAL
GNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSL
IKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKP
LWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATG
DHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLSC
AGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFI
HVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3Q7PKL9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinus ursinus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C0VEA3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyanistes caeruleus|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHIWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGHLRIGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A671T910|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPGVYGMQDVWEREGWQQVNMEFLLPTGIYLNFPVTCSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVCQMLPWDQWMEYNFPCDLEPCSVVAQS
GKSCSDKKIFVNVKFEGSEVSPQDLPMFLKRNALRKKSTVFRSAKQEKPEDYALQINGRW
EFIYGKYPLCQFKVSLKITPSSRLHSYIFFKFHIKKMFKMLNYFFFSQQQNTSSLWSIHE
PFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSNEVSVCSEPVWDQKLEFDISV
SDLPRMSRLCIALYGVIEKTKKRPTKKKNKSSDCPLAWVNTMVFDYKDQLKTGEFSLSTW
PSVPDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKHLKLREIVDNKNYTEF
FEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELL
DYSFPDPHARSFTIRCLRKLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKI
GHFLFWHLRSEMHVSSVSLRFGLILEAFCRGSIFHIKNLMKQNEALNKMKALNDFVKSGS
QKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMY
KNKYDTLGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEV
VKNSDTIANIQRNNSNSAATAAFTNLTPRHSPDKLDQAIEEFTLSCAGYCVATYVLGIGD
RHSDNIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKF
ERFRECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALK
NFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A671P774|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEMREGGGAHTQALYVYPPNVESSAELPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKITHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKQKHTPNLQNIH
>A0A8C0AVB5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Buteo japonicus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C0B8N3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Buteo japonicus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPAKNIFVNVRFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGQTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAL
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A851N8F0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Penelope pileata|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNATLGTIKQVVWKYAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPDEFPITLMSYAIKKQATVFRHETMENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRSLTPHLTMVHSSTIIAMRDEQNNCIANPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMVSLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHEVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSVHHMNVLMKQGEALKKMKALNEFVKLSSPKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A672UQS4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GPLHIPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAIKKQATVFRHETLEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKTA
TKPPPLPKKKPNYGSLWSLEQSFYIQLVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKNNRQ
>A0A8C6ANE8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monodon monoceros|TrEMBL
VCFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKDDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVDYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYIEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDHSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A5F4WEW0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callithrix jacchus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMFQEMCYKAYLA
IRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGG
WTTKMDWIFHTIKQHALN
>A0A8C7MIK5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHEVFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKCPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGESSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNRETPCLELEFDYF
SSPVKFPDMTTVEGHVLVYMDIYIYIYIYIYIHTHNRVARDHALTDSDNEQLRQVCNRDP
LSEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAM
ELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVVKYEQYLDNPLVRFLLKKALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDIL
KQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNIRLEECRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCM
SLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDLAVDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8C7H7U2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus kisutch|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRVKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDYTLQ
VNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQLSKSRSL
SKPPPLPVKKQNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVVTS
GEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPLAW
VNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIHFPNIRP
HPLYYPHFDKVHLILDSILKEIVDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKLLLI
TKWNKHEDVAQMVTFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYL
LQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYC
RGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYKDALSYLL
SPLNPSIKLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIFKNGDDLRQDMLTLQM
IQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKD
ALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFG
HFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTL
FVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNW
MMHSLAKDSRL
>A0A8C4AYE0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPTMMDVLDLWAELGEVEHVSVDFLLPTGLYIQMEVPREATIQHIKQLLWKEAAGYPLF
TLLGAMEGHMFECVNQTAVHEELEDETRRLCDVRPFLPVLRVVTRSGGHNERLLDSKIGV
LIGKGLHELDSLQDQEIKDFRTKMQQISKEKIQRIQVMSWEEWLRTHFSPQLEVGQVDGM
IEKLCEDGIKVTMHYDQSQVCTVRTLLELALRKWANTHGHNNSSCLSDYILRISSKLEIL
YYVLGICLIFVCVQYIRECLLAQESPHLTVMHSSVLRGMFERELGCIASVCGHKQSNAPL
PLPPKKRPPSVSTCSQFKITLVRGIKVNTEESAKVYVRAGLFHGAELLGKPAVSSDSSGR
LEHLWNTTLEFDVAVSDLPRMSRLCFAIYAVMDKVKKQPKSIKTPHSKYQTIRKHYPIAW
VNTMVFDYKGLLKTGDVVLYCWSSFPDELEEMLNPIGTVQTNPYTENATAIHITFPEYSQ
ISVIFPPFDKVLSFFFYLYLPFYQATFLFFFPSDEELSQYLLQLVQVLRYEPYYDCALSR
FLLERSQLNRNIGHFLFWHLRSEMHMPAVSVQFALILEAYCRSSIPHIEVLKKQVEALNK
LKAVNALVKTGAVKSKARTKDSHLKEAMLTCLRQSGFTETLSDIHSPLNPSVLLAEVNVD
RCKYMDSKMKPLWIVYNNKLLGGETLGIIFKNGDDLRQDMLTLQILKLMDLLWKEANLDL
RIVPYGCLATGDHSGLIEVVSSADTIANILKTSSNMAATAAFNKDALLNWLKEKNSGDTL
ERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRE
RVPFILTHDFIHVIQQGKTANTEKFGSFRQYCEEAYLVLRRNGNLIITLFALMLTAGLPE
LTSVKDIQYLKWNSLFCIGRVS
>A0A8C4BD78|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPGVFGMQDVWEKDGQQVTVEFLLPTGIYLTLEVSCSDTIGTIKKMLWRAARGEPLFGA
LSDPDAYVFTCINLTAEREDLEDEQRRLCDVRPFLPILRLVAREGDRVEKLINTQISHLI
GKGLHEFDSQKNHEVSEFRTKMRAFCEERAQERQRLPWYEWMESSFPCDLEPCSGLLKSS
KFHNFKKVFVNVKFEGSEVSLLRFLFSESELIVINALKKKATVFRPVRQEKPEDYTLQVL
GRWEFIYGKHPLCQFKYIWCCMHEAQTPYLTMVHHSTITKYQEEQSCLTNQVTKTRSSSK
PPPLPLKKVRGTPDMDSNHNSFISHCWMLPVLTSFYSLFQLVVQAGLFHGSELLCKVVTS
NEVNVSSEPLWDQKLVFDISVGDLPRMTRLCLALYAVVGTTKKARSTKKKNKRADCPLAW
VNTMVFDYKDQLKTGDFSLSAWPSVPDEKSDLLNPMGTVEKNPNIDSAAGLLIRFPNIRP
HPLCYPPLDKAGLKTHIYMPLYSDSLISMHGCLQHMKLKEIVDNKNQTEIFEDEKELLWK
LRVEMRDHYPESLSKLLLIGKWNKHEDVAQMVWLLRKWPDLPVLHALELLDYRFPDPYVR
SFTIKCLRKLRDDELFRYLLQLVQVLKYESYLDCDLTTFLLERALSNKNIGHFLFWHLRS
EMHVSSASLRFGLILEAYCRGNLYHIKSFMKQVTALNKMKALNDFVKSGSQKATRSQTIE
DMKVCIRQEAYMEALSDMLSPLSPSIILSEICTEKCKFMDSKMKPLWLMYKSKVAQADTV
GIIFKNGDDLRQDMLTLQMLELMDVLWKREGLDLRMVPYGCLSTGNKTGLIEVVKNSDTI
ANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLEEAIEEFTLSCAGYCVATYVLGIGDR
HSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGRTNNSEKFE
RFREYCEQAYKILCRNGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKI
FKVKFNEALRESWKTKVNWMMHSVAKDNR
>A0A8C4BFI1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPGVFGMQDVWEKDGQQVTVEFLLPTGIYLTLEVSCSDTIGTIKKMLWRAARGEPLFGA
LSDPDAYVFTCINLTAEREDLEDEQRRLCDVRPFLPILRLVAREGDRVEKLINTQISHLI
GKGLHEFDSQKNHEVSEFRTKMRAFCEERAQERQRLPWYEWMESSFPCDLEPCSGLLKSS
KFHNFKKVFVNVKFEGSEESFMLQLDPQDLPVMLMKNALKKKATVFRPVRQEKPEDYTLQ
VLGRWEFIYGKHPLCQFKYIWCCMHEAQTPYLTMVHHSTITKYQEEQSCLTNQVTKTRSS
SKPPPLPLKKQNTTSLWTIQEPFYVQLVQGSRVNADEGMKLVVQAGLFHGSELLCKVVTS
NEVNVSSEPLWDQKLVFDISVGDLPRMTRLCLALYAVVGTTKKARSTKKKNKRADCPLAW
VNTMVFDYKDQLKTGDFSLSAWPSVPDEKSDLLNPMGTVEKNPNIDSAAGLLIRFPNIRP
HPLCYPPLDKAGLKTHIYMHMNCNITLLKEIVDNKNQTEIFEDEKELLWKLRVEMRDHYP
ESLSKLLLIGKWNKHEDVAQVPSQNMVWLLRKWPDLPVLHALELLDYRFPDPYVRSFTIK
CLRKLRDDELFRYLLQLVQVLKYESYLDCDLTTFLLERALSNKNIGHFLFWHLRSEMHVS
SASLRFGLILEAYCRGNLYHIKSFMKQNEALNKMKALNDFVKSGSQKATRSQTIEDMKVC
IRQEAYMEALSDMLSPLSPSIILSEICTEKCKFMDSKMKPLWLMYKSKVAQADTVGIIFK
NGDDLRQDMLTLQMLELMDVLWKREGLDLRMVPYGCLSTGNKTGLIEVVKNSDTIANIQR
NNSNMGIPAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTK
FGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYKILCRNGTLFVNLFALMR
AAGLPELSSSKDIQYLKDSLALGKSEEEALKIFKVKFNEALRESWKTKVNWMMHSVAKDN
R
>A0A3P9KTI5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias latipes|TrEMBL
MHPGIYGMLEEWEDGDQEINMDFLLPTGIFLKFPVSRNDTIKHIKEMVWRNARSEALFSG
LGDPDGYVFTCINQTAEREELEEEFRRIRDVKPFMCVLRLVAREGNRQEKLTNTQITQLI
GKGLHEFETQKNHEVNEFRTKMRTFCEEKALERQYLPWQRWLEYSFPCDLEPCRTPSGFG
SVKMKSSKIFINVKFEASDESFMLQQDCHDLPLALMKSALKKKATVFRSLRQEPEDYILQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPQLTMVHHSTVSRFQEEQSRMCNQMFKSRSL
SRPPPLPLKRQNTSSLWSINEPFYIQLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTS
LDVTVCSEPLWDQRLEFDINVCDLPRMSRLCFALYAVIEKTKKPKSTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFLLSMWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRP
HPLYYPSLEKHLKLKEIMDNKHYTEFFEDEKDLLWKLRTEIREHYPENLSKLLLVTKWNK
REDVVQMVSLLKKWPDLPAIHALELLDYSFPDPAVRSFTVRCLRKLSDDELLQYLIQLVQ
VLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIH
HIKILNKQNEALAKMRALSDFVKSGSQKMTVEDLKLCIRQETYMEALSDLLSPLNPSIIL
TEICADKCRFMDSKMKPLWLMYKNPSTPGDMVGIIFKNGDDLRQDMLTLQMIQLMENMWK
KEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQLNSSNSAATAAFNKDALLNWLKSK
NPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRK
LGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYKILCRNGMLFVNLFAMMK
AAGLPELTCFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDN
RA
>A0A7K7TYH6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ibidorhyncha struthersii|TrEMBL
MELGDDEQPVVMRDENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A093NUF3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pygoscelis adeliae|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAVEA
AINRKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHIWNEILEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYIVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVLLSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A093PD48|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pygoscelis adeliae|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQKRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGNRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEVVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L3DP06|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pluvianellus socialis|TrEMBL
MPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GPLHTPAKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLMPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSFWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSQKATKPQTRELMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A851E331|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dryoscopus gambensis|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSDKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8D2ZPX5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNLESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARICLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCPGLTSRLACDVSVSAADAEQLRCLCSKDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLMSVKWNSRDEASQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVKGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A7K7YBT8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Thryothorus ludovicianus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNEHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDEFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A673MMZ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPILRLVAREGDRVEKLITTQISLL
IGKGLCHTNRLLTSELFGRLTMEAAKHLLTTAAELYGFGSYPQDLPMFLKWNALRKKSTV
FRSAKREKPEDYTLQVNGRWEFIYGEYPLCQFKVSLKVTTSSRLHSYIFFQIYMKAPHFQ
TSALQSLSFSQLVVQAGLFHGSELLCKVVTSNEVSVCSEPVWDQKLVFDIGVSDLPRMSC
LCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPAESI
KTTLINFFQHLKLREIVDNKNYTEFFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKH
EDVAQMVGLLRKWPELPAIHALELLDYSFPDPHVRSFTIRCLRILRNDELFQYLLQLVQV
LKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSIFL
IKSLMKQVCCIYSLCEKQINFSSALHISHVKAVTRKRKQSLFRNHLCTSVSFLDANLFCF
SADKCKFMDSKMKPLWLMYKDKYDHVGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDL
RMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKL
DQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSKFGINRE
RVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMKAAGLPE
LSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSFAKDNR
>A0A673I8P5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
LCFSFVVCAMPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLL
LWKEAQTYPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGR
AERILDSKIGVLIGKGLHELDALQDQEVKDFRSKMKQISEEKMQRMQLMSWGEWLRSCYS
MPLEAGSLENLIDKHEGVIKITMHYDQSQVCSVNLVCITELMDQALKKWQTTHGPEEDIG
FRSDYVLHVSGKLEFLFEDHPLNQCKYIRDCLLTNESPHLTLVHCDGVKAMFEKEISTIG
SVLARKTSNPPLPLPPKKRLPTIQVRAGLFHGTELLCKTAVSSESSSRSEHVWNKTLEFD
IAVCDLPRMARLCFAIYAVMDKVKKPRSTKNTHLNKYQTIRKAGKVHYPIAWVNTMVFDY
RGQLKTGDIILHCWTSFPDELEEMLNPIGTIQTNPYTENATELHINFPEYSTQPVVFPAF
DKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRYDCREN
FPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVYCLQ
DMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERSQSSRKIGHFLFWHLRSEMFMPAVS
VHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFGTIKTKTKQAHLKEAMMTCL
RQTGFIETLSDLHSPLNPNILLAGINVERCKYMDSKMKPLWIVYNNKLLEGDTVGIIFKN
GDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQKT
SSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTSNTEKFGNFRQYC
EEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFD
EALRESWTTKVNWMAHIVAHPS
>A0A673LC30|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MEHQASDDEPPVVRREENKRRRRKMKAFTSTSAVSTDHIAVEFVLPTTNKNSRNPDTLHI
DVTGNWTVEQVKVQIWHRAVTTKLYLKTLLASVFVLLTSKQLWYEIYDKQQVFQTLDCIR
YWKALRKEVGKIHLVVRTQPTEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRKLLTP
RKIELSDRDPKLYSMDPWMTTKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDDTPVQ
VLQSFFAKITNKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKNGEEI
HLVLERPPDPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRKFRV
KILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIKIKDL
PKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVDHRSLLRQGEFILHMWKMPE
KSEDNSSVNADKLTSATNPDKNSSMAVAILLDQYCYPVALPKSKDSPDSEMEGERGQREM
PNHMRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEAVTIT
HRLLERSTVWDRSSLDVGLALQLMDCHFSDENVRTMAVRKLETLAGDDVLRYLLQLVQAV
KFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGEA
MLQDFRKQVEMTEALHKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDSFKVPY
DPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDMLILQI
LLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDEIL
SQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDFGH
ILGNYKSFMGISKERVPFVLTPDFLYVMSTTGKKSSPHFLQFQPGCCCYSVLIGC
>A0A4W2I4N0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos indicus x Bos taurus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPFLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLSSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTK
PQTKELMHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEA
GSDGTVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVV
LHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYV
LGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTN
NSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTE
EEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>M7BRP5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelonia mydas|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVCPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWAINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMTVTEEHANWTISRELGFNYSHAGLMYCLVKDWPPIKPEQAMELLDCNYPDP
MVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFW
HLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQK
VQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRMLPYGCLSIGDCVGLIEVVRSSHT
IMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRSCAGYCVATFILGIGDR
HNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTRE
FERFQEMCYKAYLAIRQHANLFTFDDIAYIRKTLALDKSEQEALEYFMKQMNDAHHGGWT
TKMDWIFHTIKQHALN
>A0A7L3H9I7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Buphagus erythrorhynchus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GDYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRTSSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLDDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQGI
>A0A8C5F139|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gopherus evgoodei|TrEMBL
MPPAVTDILDIWAVDSQIGADGLISVDFLLPTGTYINLDVPRDATICHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLGSKI
GVLIGKGLHEFDALQDPEVKEFRSKMRRISEEKLLSLVGLSWVDWLKHSYPPEQEPSIPE
NFQDKLYGGNLVVAIHFDKCQDVFSFQVSPNINPVKLNELAIRKRLTIHGKEDEVDPSDY
VLQISGRLEYIFGDHPLIQFQYIRKCVMNRILPHLTLVECCSIKKMCEQEMIAIEGAINR
KSSNLPLPLPPKKTRTVTQLTHSVWDMSNPFKIMLLKGNKLNTEETAKVHVRAGLFHGTE
LLCKPIVSAEISGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKTINP
SKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDLLLHSWTSFPDELEEMLNPMGTVRTN
PYTENATALHIKFQEYSKLPIYYPPFDKILEKAAEIAKSSENAGMPGRGGKKFYIELKEI
MERDPLTQLCENEMDLIWTLRYDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWSKL
PPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLV
ERALANRRIGQMLFWHLRSEVHIPAVSIQFGVILEAYCRGSIAHMKVLSKQVEALSKLKT
LNSIIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELYVEKCKYMDS
KMKPLWIVYNNKMFGGDLLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGC
LATGDHSGLIEAVSAAETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A851ZCQ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calcarius ornatus|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSTELIPIEFILPTSNKHTKAPEIMVLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYRAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNILLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K7D071|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pheucticus melanocephalus|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKGQIWMRAIETSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3Q3NCC8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Labrus bergylta|TrEMBL
SVSDEEPKVVREETRRRRRKKAISSSSCCSMDQISVEFVLPSVVRGGSSHDTLLLEVAGN
WTVEQVKAQVWMKAVTLNLCPDFYQRLSPDHCILLYQKKGNLCEIYDKHQVFQTLDCIRY
WRALKKDVGRIQLVPRPQPSDESLQYQRYLNNLIGYDVTDVSNVHDDELEFTRRKLLTPR
RIELSDRDPKLYSMDPWVTLKPLPEHLLSKISNSHILVVIHISTVSQTIKVSIDDTPEQV
LTSFFTKIANKRVLLGIPDNTCESDFVLRVCGREEYLYGDKPLLNFNWIRQCLKNGEEIH
LVLEKPPDPDLDLVQKDDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVK
VLGIDIPSLPKIPDFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLEFNIKIRDLP
KGARLNLQVVCGKQPQTPNSKAGSGKTKTRLLYYVNLLLIDHRSLLRQGEFILHMWRMPE
KSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDTGRDMPNHLKKQFG
AIVATDPLHPLSPEDKELLWHFRHECMRDPSFSAPPPPPSPVFTSLLFSGLDVGLAMQLL
DCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRI
GHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTREMKA
TSADKYDITAQVVFQLRQKLETLQLSGLPESFRVPYDPGLRAGVLLIEQCKVMASKKKPL
WLQFKRADPTTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCIS
TGNRIGMIEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVGEDKFQQAVERFLYS
CGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDF
LYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYI
REALTVGRSEDEAQRHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A3B3ZYW7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Periophthalmus magnuspinnatus|TrEMBL
MDREQPVQLSDEEVVVIRDPRHRRRKKPICPLSHTTMDQVCVEFVLPTAARGGSSPDTLQ
IQVAGNWTVEQVKAQVWLKAVTSNLCPEFYQRFSPDHCILLYQKKGTVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQMVQRPQPTDQSIQYQRYLNQLMGYDVTDVSNVHDDELEFTRR
KLLTPRRIELNDRDPRLYCMDPWVTCKPLPQHLLSKVSNGFILVVIHIRTVSQTIKVSID
DTPEQVLSSFFAKTANKKALLGIPENMSENDYVLRVCGREEFLYGDKPLQNFNWIRQSLK
NGEEIHLVLEMPPEPDLDVVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKILGLDIPTLPKTSELIVYIEASIFHGQQLLAQERTTSKPFTEEVLWNCWLEFSI
KIKDLPKGARLNLQVVCGKQIQTPNSKTGKSKNRLLYYVNLLLIDHRSLLRQGEFILHMW
KMPEKNEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVALPKSRDMGKDLARDVG
GGEEGEGGVRGQREMPNHLRKQFEAIVSTDPLHPLSPEDKELLWHFRHECMKHPRAYPKL
LGSVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLE
DDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQR
YAVLLEAYLRGCGEAMLLDFRKQVEMTEALQKVTREVKAMSADKYDITAQVVFQLRQKLE
ALQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLCKDPIGIIF
KDGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISSGNRIGMIEIVKDATTIANIQ
QSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVEKFLFSCGGYCVATYVLGIGDRHNDNI
MITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSANFQKFQDV
CVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQI
EICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A669DCP5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
FESQVPREESRRRRRKKAITSSCSNSMDQITVEFVLPTAARGGSGSDTLQLDVAGNWTVE
QVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDCIRYWRAL
KKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTPRRIEL
SERDPKLYSMDPWVTCKPLPEHLLSKINNGHILVVIHIGTASQTIKVSIDDTPTLVLVSF
FAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLKNGEEIHLVLE
MPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVLGI
DIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNIKIKDLPKGAR
LNLQVICGKQPQIPNSKGSSYQESTAGSSRKTKSRLLYYVNLLLIDHRSLLRQGEFILHM
WKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDWAVGG
EDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHECMRVPRAYPKLLG
SVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDD
DVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRVSRHVSVCFMSSQLCVCVCYTRTITAV
KKCQVDMTEALQKVTREIKTMSADKYDVTPQVVFQLRQKLENLQSSGLPESFRVPYDPGL
RAGALLIEQCKVMASKKKPLWLQFKRADSTTLSKDPIGIIFKDGDDLRQDMLILQILLIM
ESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIANIQQSVVGSTGAFKDEILYQWL
RDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGN
YKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTNLLIILF
SMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQINWFVHLV
LGIKQGVEKRST
>A0A669D8F3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
MDRQQIQVSDEESQVPREESRRRRRKKAITSSCSNSMDQITVEFVLPTAARGGSGSDTLQ
LDVAGNWTVEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTCKPLPEHLLSKINNGHILVVIHIGTASQTIKVSID
DTPTLVLVSFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLK
NGEEIHLVLEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNI
KIKDLPKGARLNLQIPNSKGSSYQESTAGSSRKTKSRLLYYVNLLLIDHRSLLRQGEFIL
HMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDWAV
GGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHECMRVPRAYPKL
LGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLE
DDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRVSRHVSVCFMSSQLCVCVCYTRTIT
AVKKCQVDMTEALQKVTREIKTMSADKYDVTPQVVFQLRQKLENLQSSGLPESFRVPYDP
GLRAGALLIEQCKVMASKKKPLWLQFKRADSTTLSKDPIGIIFKDGDDLRQDMLILQILL
IMESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIANIQQSVVGSTGAFKDEILYQ
WLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHIL
GNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHTNLLII
LFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQINWFVH
LVLGIKQGVEKRST
>A0A8C8LRF3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MEQQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVAMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKHLPEYLLFCIGHILLVIHRNKASQTIKVSIDD
TPVQALQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCLKN
GEEIHLVLESAPNPGQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISLWDCHR
KFRFKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFNIR
IRDLPKGARLSLQVSCGKAQTQISKGTSSYQDNGGSPVGGGSGNHDCNKTKSRLLYYVNL
LLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYCYP
VALPKSREGKEAGGEGREAEGGERGQREMPNHLRKQFEAIVETDPLHPLSQEDKELLWHF
REECMRHPRAYPKLLGSVRWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYSDA
HVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWF
LRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYD
VSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVVKQCKVMASKKRPLWLQFKRA
DPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGM
IEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVA
TYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTS
GKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVG
RTEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A8C0XZ65|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Castor canadensis|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPMLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRIPNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQSLAEQPEDYA
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPTPQVQKPR
TKPPPVPAKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMVRLCFALYAVVEKTKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDDKGELLNPVGTVRSNPNTESAAALVICLPEVAP
HPVYYPALEKILELGHHEERGRITEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQPQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIK
SLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVP
SVALRFGLLMEAYCRGSTHHMKVLMKQGEALSKLKSLNDFVKVSSQKTTKPQTKELMHLC
MRQEAYLEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYGGEEAGSAGSVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2K5MPG2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cercocebus atys|TrEMBL
MPPRPSSGELFFFYLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFFCVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNFFFKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYFFFVESSPELPKH
IYNKLDKGQIIVVIWFFFSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLFFLQLK
LCVLEYQGKYILKFFFCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTFFFWVINSALRIKILCATYVNVNIRDIDKIYVRFFF
YHGGEPLCDNVNTQRVFFFNPRLFLIHYFFFKILFFFNEWLNYDIYIPDLPRAARLCLSI
CSVKGRKGAKEEHCPLAWGNFFLFDYTDTLVSGKMALNLFFFPHGLEDLLNPIGETPCLE
LEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEFFFAI
STRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIK
PEQAMELLDCNYPDFFFRGFAVRCLEKYLTDDKLFFYLIQLVQVLKYEQYLDNLLVRFLL
KKALTNQRIGHFFFCQRFGLLLESFFFSCGMYLKHLNRQVEAMDFFFNLTDILKQEKKDE
TQKFFFLVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLN
WENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIFFLENIWQNQGLDLRMLPYGCLSIG
DCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWCLLLLFFFDAAIDLFTRSCAGY
CVVFFFLGIGDRHNSNIMVKDDGQLFFLDFGHFLDHKKKKFGYNFFFVPFVLTQDFLIVI
SKGFFFCTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRK
TLALDKTEQEALEYFMKQMNDFFFGGWTTKMDWIFHTIKQHALN
>A0A8C8GYQ7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MEQQVGDEEEPQPVVLRAEIRRRRRKMKAFTSTLSVAVDQIAVEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCVRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELSDRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPENVCEADYVLRVCGREEYIYGNHPVRNFHWVRQCL
KNGEEIHLVLELAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVYTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNAWLEFN
IRIRDLPKGARLSLQVSCGKAQTQISKGTSSYQDNGGSPGGGGSGSGSGSHDGSKTKSRL
LYYVNLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILL
DKYCYPVALPKSRDGKAAGGEGREAEGGERGQREMPNHLRKQFEVIVETDPLHPLSQEDK
ELLWHFREECMRHPRAYPKLLGSVLWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLD
CHYSDAHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIG
HFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAM
SAEKYDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLW
LQFKRADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCIST
GNKIGMIEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSC
GGYCVATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFL
YVMGTSGKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIR
EALTVGRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A7F8RVY7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptonychotes weddellii|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTMRVPTRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFRVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLNMWPSVPDEKGELLNPTGTVRSNPNTESAAALIICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALSDFVKVSSQKTTKPQTKELMHLCIR
QETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDGLGPCPFGGVLCQSQHCHLRWKRGCSKKSRDQFKIRAKGGDVGPRSVRVERPGLARGV
RLAPLFPSPHASLASCPILGSGGIFFQATWISLRANMSSAKVPPFLRCSLGAGPDLSKES
SPRVPGVTDSSPAPLPSLAASPGAVLAVLSPSGWGGVSGHPRDSP
>A0A671WNN6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sparus aurata|TrEMBL
MDGKQIQVSDEEPRVVREETRRRRRKKAITSSSCSSMDQITVEFVLPTTARGGNSPDTVL
LDVAGNWTVEQVKAQVWLKAVTLNLCHDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDPKLYSMDPWVTRKLLPDHLLSKVSNNHILVVIHIGTVSQTIKVSID
DPPAQVLASFFAKTANKRVLLGIPDDMCEEDFVLRVCGREEYLYGEKPLHNFNWIRQCLK
NGEEIHLVLESPPDPELDQVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVNTPLYLSHPGGKTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMP
EKSEESSSSINADKLTSATNPDKASAMAIAILLDKYCYPVVLPKSRDVGRDVGAGGEEAE
GGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRW
GKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLR
YLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLE
AYLRGCGEDMLQDFRKQVEMTEALQKVTREVKAMSADKYDITAQVVFQLRQKLENLQSSG
LPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDL
RQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGS
TGAFKDEILYQWLRDKCVSEDKFQQAVEKFLYSCGGYCVATYVLGIGDRHNDNIMITESG
NLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQVLYYKSDV
CVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQI
EICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A6J0D857|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Peromyscus maniculatus bairdii|TrEMBL
MPPGVDCPMDFWTKEESQSVAVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEVAAHRQQLGWEDWLQYSFPLQLEPSARSWRA
SILRVTNRALLVNVKFEGSEESFTFQVSTNDMPLALMACALRKKATVFRRPLVEQPEDYA
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPAKKPSSVSLWSLEQPFCIELIEGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVICLPEVAP
HPVYFPALEKILELGRHGERGRVTEEELQLREILERRGSGELYEHEKDLVWKLRHEVQER
FPEALARLLLVTKWNKHEDVAQLSQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIK
SLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVP
SVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMC
MRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGSVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A851F4X5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pitta sordida|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPALPRNTDLTVFVEANIQHGQQLLSQRRTSAKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPATKTNVQSHESSNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPVALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6Q2YBX4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLTSIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFEQVKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPPNVESAPELPQH
IYCKLDKGRLIVTIWVIVSPSNSKQKYTLKISHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYVRGCITMGRLPHLMLVSKDSLYSQLPGS
GFVAPSYSRRTPQPSPCPGGGDPSTPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDTLVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQVVLFPDEQQIEEHANWTISRELGYNYCLGLSSRLACDSSVSVADGEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEWSQMYCLLRDWPLMQPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWDNPDIMSELLFTNNEVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECTKTKEFERNPNSNYEINCNFDPKP
>A0A6Q2XD37|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
MAKQVSDEDLHSVVHREENRRRRRKMKAFTSTFSVIMDQISIEFVLPTSTKSSRSPDTLL
LEVAANWTVEQVKAQVWLRAVASNLCPEFYQKFSPDHCILLYQKKGNWCEIYDKHQVFQT
LDCIRYWKALKKDVGKIHLTCRPQPSEDSVRYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLFSPRRIELSDRDPKLYSMDPWITSKPLPEYLLAKVTNNHILLVIHKSTASQTIKVSID
DTPVQVLQTFFAKIANKRALLGIPDDMCEADYVLRVCGREEYIYGNHPVRDFHWIRQCLK
NGEEIHLVLESAPNPEQDQVQREDWAQVDDCTGVAGTHEQLTIEEKDHERVFTISLWDCS
RKFRVKVLGIDIPTLPRNPELIVFVEASIFHGQQLLAQERTTSKAFTEEVLWNTWLEFNI
RIRDLPKGSRLSLQVSCGKAQTQPTKGGGGHDKTKSRLLYYVNLLLVDHRSLLRQGEFIL
HMWKMPEKTEDNSSVNADKLTSATNPDKASSMALAILLDKYCYPVALPKSRESKEPGGDG
RSAEGGERGLREMPNHLRKQFEAIIETDPLHHLSPEDKELLWHFRQECMRHPSAYPKLLS
SVRWGRQEAVLATHRLLERSTVWDRSPLDVGLAMQLLDCHYSDANVRSMAVRKLETLGDD
DVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIATSMHYQQRYA
VLLEAYLRGCGDDMLQDFRHQVEMTEALQKVTREIKTMSAEKYDVSAQVVFQLRQKLENL
QTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTRSSDTIGIIFKD
GDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQS
VVGSTGAFKDEILNQWLQDKCVNEEKFQQAVERFVFSCGGYCVATYVLGVGDRHNDNIMI
TESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFLKFQDVCV
RAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGHPEEEAQRHLLDQIEI
CRDKGWTVQFNWFLHLVLGIKQGVEKRSA
>A0A803TWD5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anolis carolinensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVDLRDVNAPHSRALYVCPPNIESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGESSAKSLWAINSNLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLQYEMQVLDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMSVIEDHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLHAICTRDPL
SEITEQEKDFLWSHRHYCVNMPEILPKLLLSVKWNSRDEVAQVLKYEQYLDNLLVRFLLK
KALTNQRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINL
TDILKQEKKDETQKVQMKFLVEQMKRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSA
KRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLP
YGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDPAID
LFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFV
LTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQS
FDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A803TDX4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anolis carolinensis|TrEMBL
MLPGIYCPVEFWSKEANQSIQVDFLLPTGIYLTLSVSCNATLGTIKQLVWHHAQCEPFFH
MLSDPESYVFTCINQTAERQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLISSQISLL
IGKGLHEFDSLGDLEVDDFRVKMQHFCEERAARRQQLSWKAWMEYSFPVQLEPLANGLGG
RSLLQFPNKNIFVNVKFESGGESFTFQISPKEYPATLMSYAIKKQATVFRHQKINSPEDY
ALQINGKYEYLYGNHPLYQFQYIRDCLCRGLLPHLTMVHASSISALWEEQTNGISYPIKA
ASKAPPVPKKKPMSVSLWSLEQPYSIELVQGSKVNADERMKLVVQAGLYHGHEMLCKMVS
SSEVSVCSEPVWGQRLEFEINVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIA
WVNVMLFDFRDQLKTGECCLPMWSSFPDEKGELLNPMGTVQTNPNTESAASLVIRFPTIS
SNPLYYPTFEQKHNECTIHSGKQQLKEILERRSHTDLYEHEKDLVWKMRHQIRDQFPHAL
AKLLVVTKWNKHEDVAQMIYLLQSWPELPVLNALELLDFSFPDRYVGAFTVNSLKKLTDA
DLFQYLLQLVQVLKYESYLDCELTKFLLGRALSNRKIGHFLFWHLSSQKNAKPQTKEFMH
TCMRQETYLEALSNLQSPLNPSVILAKVSVELCTFMDSKMKPLWIVFNNEDAGGGHVGVI
FKNGDDLRQDMLTLQMIQLMDILWKKEGLDLRMTPYGCLSTGDKTGLIEVVMDSDTIANI
QLNKSNMAATAAFNKDALLNWLKSKNPGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFR
EYCERAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEARRHFQL
KFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A0U4VVP9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Halocynthia roretzi|TrEMBL
MAPSSDYSSASGELWGLPLMPSTIEVELLLPNGIYLTLEAARELTLHNLKDMVWKQALRY
PLYNELMEQGSYIFVGVTQDAECEEFYNEKRRLCDLHLFQPILRLVESEGNVQEKLLKNE
IRQAIGMSVDEFDRISSQEVDDFRRNISTFCKSVIDKRLECTDALALIKYRYPPCMESAP
TLPPHTKSKLLINRSWLVVRLWDKKSLQHTKLSIKVSYNATPSEVLTEALKKFSRLHKDI
YPEKVRNISLKELESAGMYTLKVCGLNEYIVGNFPICQYRYIRQCVNRGINPDLMVVPTR
DIIKNITSNVQYLQPQIAKCKPVTPNESLKLISRDILFRLHVISAAYVNTKEQDHTYIYV
NLYHGSSPLCEPQKTSGMLCPPKWNEWLEFDIALCDMPRSIKLCISICALRKKKDKDEHW
PLAWANIPLYDYLGCLLQGKVTLHLWPSSHLVEGSVHPLGVSGSNPCMDSPSVEVEFEDY
GVEVLYPVDITSINCNLPVKSGQANGVDKSDNTKIDFTDINSNLDISSFSQIRDIISRDP
LYEMSDDEKDLMWNNRKWCLQIPESLSKLLQSVKWENRHEVSQIYTLLRYWQILPPEIAL
ELLDSKYPDPNVRAFATKCLQQTLSDDELLKYLLQLVLALKFEPYLLSPLAKYLLSKAMV
NHQVCHYLFWHLKSEMHNKKVTLKFGLLLETLCRSCGSYLSDLTNQTEMLDKLVNLNTIL
KKEETLMCKMFRDHLAKPDFKELFENNTNPINPSQRLGELLSDLSEVKLSAKRPFVLKWR
NDDPLASYFQPRWGILFKNGDDLRQDMLTLQIFKVMDDIWQRDGLDLCMTPYKCISMGYE
IGMIEIVEKAETIMSIQKKGGVVGSLQLKSGMLHQWLRDKNPIELQYDSAVTNFTKSCAG
YCVATFILGIGDRHNDNIMIKENGQLFHIDFGHFLNHKKKKYGIRRERVPFVLTDDFLKV
ICRGGNDAQNTVEFANFQDLCCKAYLSIRSHSKLILNLLSMMLGAEIPELSSFDDLEYVR
QTLAVQQSESHANRRFRECMSDAHSGRWTTRVDWVCHAVKQGILKT
>A0A851BRT8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Picathartes gymnocephalus|TrEMBL
MELGDREQPVVMREENKRRRRRMKPHCTSNSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHSFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPRLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFYWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQAPSAKTSLQSHESSSSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVV
>A0A096NG14|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Papio anubis|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7N4PIB5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sarcophilus harrisii|TrEMBL
MCLSFIMPPAMADNLDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISNIKQMLW
KQAHNYPMFNLLMEIESYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKVITRNCDPGE
KLDSKIGVLIGKGLHEFDALEDPEVNEFRSKMRQFSEEKIQSLVGLSWIEWLKHTYPPEQ
EPSIPENLEDKLYGGNLVIAVHFENCQDVFSFQVSPNMSPIKLNELVVRKRLTIHGKEDE
VDPYDYVLQVSGRLEFVFGDHPLIQFQYIRNCVMNRTLPKLTLVECCNIKKMFEQEMIAI
EAAINRNSSNLPLPLPPKKTRLISNVWDNTQPFQVILVKGTKLNTEESVKVHVRAGLFHG
TELLCKPVVSSEISGRNDHVWSEPLEFDINICDLPRMARLCFAVYAVDKVKTKKSTKTIN
PSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDIILHSWSSFPDELEEMLNPMGTVQT
NPYFENATTLHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSGNVSSRGGKKFHAVLKEI
MERDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWPKL
PPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFML
DRALANRRIGQFLFWHLRSEVHIPAFSVQFGVILEAYCRGSVGYMKVLSKQVEALNKLKT
LNSLIKLNAVKLNKAKGREAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDS
KMKPLRIVYNNKVFGGDPLGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGC
LATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEF
TLSCAGYCVASYVLGIGDRHSDNIMVRKTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKVRT
>A0A7N4PE44|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sarcophilus harrisii|TrEMBL
MPPGVDCPMEFWSKEENQIVEVDFLLPTGVYLNFPVSRNANLSSIKEVLWHNAQSEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVARQGDRVKKLINSQISLL
IGKGLHEFDSLGDPEVNDFRTKMGQFCEEAAAHRQQLGWEAWMHYNFPLQLEPSARGLGA
GALRGPSRTLFVNVKFEGNEESFTFQVSPNDFPLALMACALKKRVTVFRQPALERPEDYT
LKVNGKYEYLYGSYPLYQFQYICRCLHNGQTPHLTMVHCSSILAMRDEQSNFPAQTPKLR
TKPPPIPMKKLVVLAGLFHGNEMLCKTVSSSEVTVCSEPVWKQRLEFDINVCDLPRMARL
CFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWSSVPGTAA
LEPEGPVGLGGGCEWGEAQPLLLRPAEPHGHRLQQLREILERKVAGELYEHEKDLVWKMR
HEIQEQFPEALARLLLVTKWNKHEDVAQMLFLLSSWPELPVLSALELLDFSFPDRHVGSF
AIQSLRKLTDDELFQYLLQLVQVLARVPPDRVTVPAGRPHRKIGRSSLSSEMHVPSVALR
FGLIMEAYCRGSNHHMKALMKQGEALNKMKALNDFVRVSSQRTTKPQTKELMHVCLRQEI
YMEALSNLQSPLNPSTLLSEVCVEQCTFMDSKRSRGSQAAGEAAGSCSPGIIFKNGDDLR
QDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSMGDRTGLIEVVSHSDTIANIQLNKSNMA
ATAAFNKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESG
QLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRSYCERAYT
ILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFNEALRE
SWKTKVNWLAHNVSKDNRQ
>A0A812E1F8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sepia pharaonis|TrEMBL
MVISFFFSFSFFFLSFYLFFFFFFFFCSFLSFFLSFFSILFLSSFSFPNFLSLLSDSISF
FLFSFFLKKNTSISFFFSFLLISSRTLSFFFLFLSFFLSYFFSRFISSFYSFFFLFLHLD
SFFLSFFLSKFLFSFLSLFFFLFFFFSFSLSFFSFFFLSLIFLFLFFFLIFLFSISIFSF
FFLFFFWHLLSKFYFFYFFLSFFISFLKKILSTFFLSTFFSFFSYFFSHSFFLFFFLSFN
FLSLSFVFFFLSFFLIT
>A0A3B4TYD2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola dumerili|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEIQDFRRAILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKGPAALRHLRQRQHQGHRQDLREDRYLSWWRAAV
>A0A4W5R2B2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MEIILSDEEEPQPVVLREENRRRRRKMKAFTSTFSVTMDQIPIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELADRDPKLYSMDPWITSKQLPEYLLTKVTNSHILLVIHRNKASQTIKMSV
DDTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNQPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERIFTISLWDC
HRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNTWLEFN
IRIRDLPKGARLSLQISKGTYQDNGGSPVGGGSGNHDGNKTKSRLLYYVNLLLVDHRSLL
RQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMVVAILLDKYCYPVALPKSREG
KERGQREMPNHLRKQFESIVETDPLHPLSQEDKELLWHFREECMRHPRAYPKLLGSVRWG
RQEAVLTTHGLLERSSVWDRSVLDVGLAMQLLDCHYSDAHVRSMAVRKLETLGDDDVLRY
LLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEA
YLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEKYDVSAQVVFQLRQKLENLQTSGL
PESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRADPTTLSSDTIGVIFKDGDDLR
QDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSVVGST
GAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVATYVLGVGDRHNDNIMITESGN
LFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVRAYLA
LRQHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVGRPEEEAQRHLLDQIEICRDKG
WTVQFNWFLHLVLGIKQGVDKRSA
>A0A4W5LTN4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDTQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLPEP
GGNKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKQNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKV
VTSCEVNVCSEPLWDKKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCP
LAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFPN
IRPHPLYYPHFDKLRDLEKNGGKVIATKVEHMKLKEIVDNKNYTEFFEDEKELLWKLRGV
VRERYPESLSKLLLITKWNKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTI
RCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHV
SSVSLRFGLILEAYCRGNIYHIKNLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKL
CIKQEAYMEALSYLLSPLNPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIF
KNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQ
RNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDN
IMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRE
CCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVK
FNEALRESWKTKVNWMMHSLAKDSRL
>A0A4W5JWY5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MEQQVSDEEEPQPVVLREENRRRRRKMKAFTSTFSVTMDQIAIEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCIRYWKALKKDVGKIHLTCRPQPSEESTLFQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELSDRDPKLYSMDPWITSKHLPEYLLTKQKIANFCCLFPEDVCEADYVLRV
CGREEYIYGNHPVRDFHWVRQCLKNGEEIHLVLESAPNPDQDLVQREDWAQVDDCTGVAG
THEQLTIDEKDHERVFTISLWDCHRKFRVKVLGIDIPALPRNPELIVYVEASIFHGQQLL
AQERTSSKAFTEEVLWNTWLEFNIRIRDLPKGARLSLQVSCGKAQTQISKGTSSYQDNGG
SPTKSRLLYYVNLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASS
MAIAILLDKYCYPVALPKSREGEREQREMPNHLRKQFEAIVETDPLHPLSQEDKELLWHF
REECMRHPRAYPKLLGSVRWGRQEAVLTTHRLLERSSVWDRSVLDVGLAMQLLDCHYSDA
HVRSMAVRKLETLGDNDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLFWF
LRSEIAQSMHYQQRYAVLLEAYLRGCGEGMLQDFKCQVEMTEALQKVTREIKAMSAEKYD
VSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFKRA
DPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKIGM
IEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYCVA
TYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTS
GKKSSPHFQKFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALTVG
RPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVEKRSA
>A0A8C2ZVN2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
RELDEEPKVLREDTRRRRRKKAISSSSGASMDQITVEFVLPTAARGGSGPDTLPLEVAGN
WTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDCIRY
WRGTIRRHKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLL
TPRRIELSDRDAKLYSMDPWVTRKPLPEHLLTKVNAHVLMVIHIRTASQTIKVSIDDTPA
QVLVSFFAKTANKRVLLGIPDSMCEADFVLRVCGRFVGDSVFNGWYPTCLKTVFDDVCNP
SAPFRGNNSPANLSLSGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVLGIDIPSLPKIP
EFIVFIEASIFHGQQLLAQERTSSKTFSEEVLWNCWLEFNIKIKDLPKGARLNLQVNTKS
RLLYYVNLLLIDHRSLLRQGEFILHMWKMPEKSEESSSSINADKLTSATNPDKASAMAVA
ILLDKYCYPVVLPKSRNAGNRDDGGRDREMPNHLKKQFAAIVATDPLHPLSPEDKELLWH
FRHECIRDPRAYPKLLGSVRWGRQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSD
AQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFW
FLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTREMKAMSADKC
DITAQVVFQLRQKLETLQLSGLPESFRVPYDPGLRAGALMIEQCKVMASKKKPLWLQFKR
ADPTTLSRDPIGIIFKDGDDLRQDMLILQILLIMESIWETETLDLCLLPYGCISTGNRIG
MIEIVKDATTIANIQQSVVGSTGAFKDEILSQWLRDKCVSEDKFQQAVERFLYSCGGYCV
ATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGT
SGKKSSPHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTV
GRSEDEAERHLLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A8C9S0B4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHQ
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKESVDLRDASGPHSRALYVYPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKESLYSQLPTD
TFAMPSYARRISTATPYMNGEASAKSLWTINGTLRLRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIADIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGITGSNPNKETPCLELEFDYF
GSPVKFPDMATIEEHANWSISRELGFNYCHAALSNRLARDNTLTDIDSEQLRLVCNRDPL
SEITEQEKDFLWRHRHYCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPVIKPEQAME
LLDCNFPDPMIREFAVHCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEAVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDLAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVICKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8D0CIF8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MEQEVCNDDQPVVFREENKRRRRKMKAFTSSVFKMTDLITVEFVLPTSPKTGKGFDSLQL
DVAGNCTVEQVKAQVWVKAIATNLCPEFYQKYSPDHCILLYQKKGNWYEIYDKHQVFQTL
DCICYWKTLKKEVGKIHLTIRPQLSEESIQYQKYLNYLIGYDVTDVSNVHDDELEFTRRK
LLTPRKNELLTRDPKIYSMDPWITTKPLPEYLLSKISKNHILLVIHRNTSSHTVKVSIDD
TPNQVLQSFFTKIAKKRALLGIPEEVSESDFVLRVCGREEYIYGNYAIKDFHWIRQCLKN
GDEIHLVLETAPDPEQDVVHKEDWSQVDICTGLAATHEQLTIDEKDHEKVFTISLWDCNR
KFRVKILGIDIPTLPRNSELIVFVEASIFHGQQLLAQEKTCPKPFTEEVLWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTQPSKTAYPDSASHESKSKSRLLYYVNLLLVDHRSLLR
QGEYVLHMWKMPEKTEDLGSINADKLTSATNPDKGNSMAIAIMLDKYGYPVALPMSTEPS
ESSEGEDDERGHREMPSHLRKQLEQIVATDPLYPLSPEDKELLWHFRQECLRIPRAYPKF
LSSVKWGSQEAVLITHQLLARSSSWNQSPLDVGLAMQLLDCHFSDAMVRSLAVRKLEKLC
DDDVLRYLLQLVQAVKFEPYHDSALAQFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQR
YAVILEAYLRGCGDAMLQDFRKQVEITEALQKVTREIKAMSVEKYDVSVQVVFQLRQKLE
NLQTSGLPESFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFRRADPTTLSSDTIGIIF
KDGDDLRQDMLILQILLIMESIWEAESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQ
QSTVGNTGAFKDEILNQWLRENCPTDDKFEQAVERFVYSCAGYCVATFVLGIGDRHNDNI
MITESGSLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTTGKKSSPHFQKFQPC
VLCCRVRLRFDVCVKAYLALRHHTNMLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGRS
EEEAQRHFLDQIEICRDKGWTVQFNWFLHLVLGIKQGGEKRSA
>A0A8C9W397|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scleropages formosus|TrEMBL
MAPGVYCLPNMWEGGVQQVKMDFLLPTGIYLSFGVSGNDTIGAIKKTLWRNAKNEPLFFA
LSDPDAYVFTCINHTAEQEELEDEQRRLCDVRPMMPILRLVAREGDRVEKLITSQISLLI
GKGVHEFDTMKNHEVNEFRTKMRTFCEELAMDRQRLPWQKWIEYSFPCDLEPCALLSHSG
NLRNRASKKIIVNVKFEASDESFTLQVEPQEVPLTLMKSALKKKATVFRPMKQEKPEDYA
LQVNGRWEFIYGNFPLCQFKYIFNCLHSGVTPHLTMVHYSTITKYQEEQGGISREISKNR
SSSKPPPLPLKKTMSSLWSIQDAFSIHLMHGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SSEVNVCSEPVWDQKLEFDINVCDLPRMTRLCFALYAVIEKSKKPRSTKKKNKKADCPLS
WVNTMVFDYKDQLKTGEYYLSTWPSVPGNSLGLEKMFQANKMSMSTNANQNSYLSVVLPH
HSVFFCYMGMWLRQVHCVQYQSLSEIVENKNYTEFFEDDKEILWKLRYEVREKYSESLSK
LLLITKWNKHEDVAQMVSLLQKWPDLPALHALELLDYSFPDRNVRSFTIRCLRKLSDDEL
FQYLLQLVQVLKYESYLDCDLTKFLLERALSNKKIGHFLFWHLRSEMHVPSVNLRFGLIL
EAYCRGSIYHMKTLMKQNEALNKMKSLNDFVKSASQKGTRTQTTGEMKKCIKQETFMEAL
SDLLSPLNPSLILSEICPDRCKYMDSKMKPLWLVYKNEKVQGDPLGIIFKNGDDLRQDML
TLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAA
FNKDALLNWLKSKNPGDKLEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFH
IDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEQAYKILCR
NGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKT
KVNWMVHSVSKDNR
>A0A8B9QCF1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Apteryx owenii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWSINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEETP
CLELEFDWFSNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQL
RAICTRDPLSEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWP
PIKPEQAMELLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVR
FLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEK
LINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRI
MSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDL
RMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYD
AAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRER
VPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMP
ELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C5WK10|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptobrachium leishanense|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMMVVLECLREATLINIKHELFKEARKYPLHH
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRKNILNVCKDAVELRDANGPISRALYVYPPNVESSPELPKH
IESKLDKGQIIVVIWVIVSPNNEKQKYSLKINHDCVPEHVIAEAIRKKTRSMLLSTEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKDSLYSQIPVD
TFTMPSYSRRISTATPYMNGESSAKSLWAINSTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGAEPLCDNVNTQRVPCSNPRWNEWLLYDMFIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDCF
SSPVKFPDITAIEEHANKVLERELGYNYSHVGPANRIARDNEVRESDKEQLKAISNRDPL
SEITEQEKEFLWSHRHYCLNTPDILPKLLLAVKWNCRDDVAQMYCLLKDWLALRPEQAME
LLDFNYPDRMVRSFAVTCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHSKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMKRPDFMDALQGFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSEMLFHNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRCSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGETFQEMCYKAYLA
IRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGG
WTTKMDWIFHTIKQHALN
>A0A672ZSJ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
STLSDEEPVVLREENRRRRRKKAITSSSCTSMDQIAVEFVLPTAARGGNSPDTLQLEVAG
NWTVEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDCIR
YWRALKKDVGRIQLVPRPQPSDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLLTQ
RRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVCNGFILVVIHISTASQTIKVSIDDTPAQ
VLSSFFTKTANKRVLLGIPENTGEKDFVLRVCGRYKEYLYGDKPLQNFNWIRQCLKNGDE
IHLVLETPSDPEADLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFR
VKVLGIDIPSLPKVPELVVFIEASIFHGQQLLAQERTTSKTFNEEVLWNCWLEFNIKIRD
LPKGARLNLQSHKGKFQVYSSKAQNLIPVCCLSGKTKSRLLYYVNLLLIDHRSLLRQGEF
ILHMWKMPEKSEESSSSSINADKLTSATNPDKASSMAITILLDKYCYPVVLPKSRDVCRD
GGTWGEEAEGGERGQREMPNHLKKQFEAIVATDPLHPLSPEDKELLWHFRHECMRHPRAY
PKLLGSVRWGKQDDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLE
TLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHY
QQRYAVLLEAYLRGCGEAMLQDFRKQVEMTEALQKVTREIKAMSADKYDVTAQVVFQLRQ
KLETLQLSGLPESFRVPYDPGLRAGTLLIEQCKVMASKKKPLWLQFKRADPSTLSKDPIG
IIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIA
NIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHN
DNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKF
QDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRCEDDAQRHLL
DQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A8C3LP11|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysolophus pictus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINSIANPPKMA
VKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALLICFPNVAS
HPVYYPSFEQLLELGRNGEQPRSAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRHD
IRDQYPQALAKLLTITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHV
CMKQETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLACAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRG
YCEKAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P3RQV6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pteropus vampyrus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYAHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8B9TWT2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMLVAEVA
ACTRGGKLFVYGWERSTDPSSFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYTL
QVNGKYEYLYGNYPLYQFQVSLLSSFISESVPLCPLPNYGSLWSLEQPFYIELVQGSKVN
ADERMKLVVQAGLFHGNEMLCKMVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFAL
YAVIEKAKKARSTKKKSKKAVSKDCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGE
LLNPMGTVQCNPNTESAASLVICFPNVASHPVYYPSFDKPFGLRLSPLYALFCDSHEQKL
QLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQ
TWPELPVLNALELLDFSFPDRYVVFYFAFLSTEITNCSKYLLQLVQVLKYESYLDCELTK
FLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHIKVLMKQGEALNK
MKALNDFVKVSSQKATKPQTKEMMHVCMKQETYLEALSHLQSPLNPSIILAEVCVDQCTF
MDSKMKPLWIVFNNEETSGGGVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTP
YGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAI
EEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPF
ILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCS
KDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8B9VDP5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas zonorhyncha|TrEMBL
LCFNRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQY
EPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINS
QISLLIGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPML
VAEVAACTRGGKLFVYGWERSTDPSSFTFQIAPDEFPITLMSYAIKKQATVFRHETMESP
EDYTLQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANT
PKMSPKPPPLPKKKVKGHGSFVNGSNPRGLTVFSYFFSPQLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVSKDCP
IAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPN
VASHPVYYPSFDPLYALFCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYP
QALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKL
TDNELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALR
FGLILEAYCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCMKQET
YLEALSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIFKNGDDL
RQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNM
VATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRET
GQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAY
MILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALR
ESWKTKVNWLAHNVSKDNRQ
>A0A8B9TUA0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GLLHTPTKNIFVNVKFQSGGESFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANTPKMS
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPNVAS
HPVYYPSFEQLLELGRNGEPPRTMISLLQTWPELPVLNALELLDFSFPDRYVGSFITNCS
KYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILE
AYCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCMKQETYLEALS
HLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIFKNGDDLRQDMLT
LQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATAAF
NKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHI
DFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILRRH
GLLFLHLFALMKAAGLPELSCSKDIQYLKVRKAEPGYS
>A0A6P6BZT4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pteropus vampyrus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQFEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSSKDVPLSLMACALRKKATVFRQSLVEQPEDYA
LQVNGRHEYLYGSYPLCQFQPSSVSLWSLEQPFCIQLIQGSKVNADERMKLVVQAGLFHG
NETLCKTVSSSEVNVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKK
SKKADCPIAWANLTLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAA
LVICLPEVAPHPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRASGELYEHEKDL
VWKMRHEVQERFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDSSFPDR
HVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELAKFLLDRALANRKIGHFLFWH
LRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPQ
TKELLHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGS
EGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLH
SDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLG
IGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNS
EKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEE
ALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2Y9REH7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Trichechus manatus latirostris|TrEMBL
MDLQNDEPPVVLRADNFRRRRRMKPRSTAASLSSMELIPIEFVLPTSHRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRFGPDHFLLLYQKKGQWYEIYDRYQVVQTLD
CLRYWKVLRRSPGQIHVVQRHAPSEETLAFQRQLTALIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLSKKIANNCIFLVIHRSTTSQTIKVSADDT
PDTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSSESKGKLQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKYPKAYPKLFSSVKWGQ
QETVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSVEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSKETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEILNHWLKERCPLEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPYFQKFQQMEAALPFKK
SKWTGTLLFIEEYL
>A0A7N6C1L7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQSKYILKVCGCDEYLLEKHPISQYKYIRSCMMLGRLPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHSNWTISRELGFNYNLSGQVITCLSNNSDWATRVQQLKSFSEIEHY
CMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAMELLDCNYPDPMVRHFAVR
CLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSEMHN
KTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMRFLVD
QMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMSEMLFQNN
EIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRSSHTI
MQIQCKGGLKGALQFNSNALHQWLKDKNKGEMYDLAVDLFTRSCAGYCVATFILGIGDRH
NSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECAKTKEF
ERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKSEQEALD
YFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8J6DEN3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Galemys pyrenaicus|TrEMBL
MPRSQTPRRGPALRPLRAPRCRREAPALPPLRDPPAGSPGQPSPGRPGPAPGTDTRYEPT
CAGVCGVPMPPRRTPGFVRLGREPGPSLSLWLTVACDLLSPNRFSVPLKLSPLSSKLALP
RPSSLLGPISSADWFAPLESPEHLPEALQVPGASRFSRMPPGVDCPMEFWTKEENQNVAV
DFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFHMLSDPEAYVFTCVNQTAEQQEL
EDEQRRLCDIQPFLPMLRLVAREGDRVKKVINSQISLLIGKGLHEFDSMRDPEVNDFRAK
MRQFCEEAALRRQQLGWEAWLQYSFPLQLEPSARSWGLGTLQLPNRALLVNVKFEGSEES
FTFQVSTRDVPLALMACALRKKATVFRQPLVEQPEDYTLQVNGKHEYLYGSYPLCQFQYI
CSCLHSGLTPHLTMVHSSSILAMRDEQSSPAPQAQKPRTKPPPIPMKKVSVHLAPPSSLP
HTSCLAVQSPGQGPGPAGAGDPLSRALWLGTGRWARGCGRRASLKDGVGRHEPRTDSRVA
AALSVSSEPRGLLSGPLSLHGQPSSTSLWSLERPFCVELIQGSKVNADERMKLVVQAGLF
HGNETLCKTVSSSEVSVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVIEKARKARSTK
KKSKKAVCAASGKLGRQLVQLWTPRQAPLGLQTWPPWAPGLRAEAGRLAWAGQESPCPCD
WPSNVPTPLLSRAGLLGHVDCPIAWANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNP
TGTVRSNPNTESAAALVICLPEVAPHPVYYPALDKILELGRHGEYGRFTEEEQLQLREIL
ERRGSGELYEHEKDLVWKMRHEVQERFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELP
VLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLD
RALANRKIGHFFFWHLRSEMHVPAVALRFGLIMEAYCRGSTHHMKVLMKQGEALNKLKAL
NDMVKVSSQKTTKPQTKELMHLCMRQEPYLEALSNLQSPLDPSTQLAEVCVEQCTFMDSK
MKPLWVMYSNEEAGSDGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGC
LSTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLRSKNPGEALDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILT
YDFVHVIQQGKTSNSEKFERFRDYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDI
QYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q4G7E6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neolamprologus brichardi|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFSEARKYPLYH
LLQVYALNFDPKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLRLCVQEYQGQYILKV
CGCDEYLLEKFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPASGFVTPSYSRRTPQP
SPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVN
TQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDY
KDILVCGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFSWFNQIVVFPDEQQI
EEHANWTISRELGYNYCHGLSSRLACDSSVSSGDAEQLRSLCSKDPLYELSEQEKDFLWR
HRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESALELLDCNFPDPMVRE
FALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFFWHLKS
EMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQKTQMK
FLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELL
FTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVKN
SFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTRSCAGYCVATFILGI
GDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGIQESTK
TKEFERFQEMCYKAYLAIRQHASLFINLFSLMLGCGMPELQSFDDIAYLRKTLALGKTGQ
EALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>U6DTV6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neovison vison|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQ
>A0A8C7AMM6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neovison vison|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSVLENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDQPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSKINPPATHSLFRQILNAYMPGTIGPVSVISKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>G3TFN6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Loxodonta africana|TrEMBL
MPPAMADILDIWAVDSQITSDGSIPVDFLLPTGIYIQLEVPREATISHIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVKPFLPVLKLVTRSCDPGEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRRKMRKFSEEKIQSLIGLSWMDWLKQTYPPEHEPSILE
NLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDEVSPCDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFTLVECCKIKKMYEQEMVAIDAAINR
SSSDLPLPLPPKKTRIISHVWENKHPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TVVSAEISGKSDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQ
TIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDGANVSSRGGKKFLAVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALA
NRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLI
KLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPL
WLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGD
RSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCA
GYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFGRFRQCCEDAYLILRRHGSLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A091WLV0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Opisthocomus hoazin|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRVKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTVVSTEISGRSDHVWNEALEFEINICDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMTGRGGKKFYVVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3Q3KQT4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A672HG94|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salarias fasciatus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKIFYTILSSFFFSPKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLKMCVQEYQG
KYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMDNFTMPSYA
RRISTATPYMNGETATKCLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGIYHGGEQLC
DNVNTQRVPCSNPRWNEWLNYDMYIPEIPRAARLCLSICSVKGRKGAKEEHCPLAWGNIN
LFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSCPVKFPD
MTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNDQLRQVCNRDPLSEITEQEK
DFLWRHRHDCTNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNFPD
PMIRDFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFF
WHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLKQEKKDEAQ
KVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWENPDM
MSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLI
EVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRSCAGYCVAT
FILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGT
QECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLAL
DKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTILLFHLSSL
>E2I6G1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|TrEMBL
DKTEQEALEYFMKQMNDARHGGWTTKMDWIFHTIKQHALN
>I3LJB7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVSADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKTSAEMPSPESKGKAQLLYYVNLLLIDHCFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A286ZVK7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRYDAAIDLF
TRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLT
QDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFD
DIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A6B0R7F2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A218UV10|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lonchura striata domestica|TrEMBL
MPPAVTDSLDIWAVDSQIAADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMSRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTTVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVKVISYCLLACNINCSIYVSDELEEMLNPMGTVQTNPYTENATALHIRFQEY
SKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDIMERDPLSQLCENEMDL
IWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQVREKTMMLIAIHMRPTCVLTCHFFLEQ
LQALLQIWPKLLPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEP
FLDCALSRFLLERALGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLA
KQVEALNKMKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSE
LHVEKCRYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEA
GLDLRILPYGCLATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNL
GEDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFG
IKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTA
GLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A852H2S8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Larus smithsonianus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSANLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFRKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7K7EBX9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sylvia atricapilla|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWQQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEEKAAKRQQLSWADWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEMPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKAA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVAVCSEPVWRQRLDFDIGICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
YPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>G3RFK9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gorilla gorilla gorilla|TrEMBL
MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGIPGK
>A0A7N5JJS2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ailuropoda melanoleuca|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRHSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKISNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLLDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIQI
KDLPRGALLNLQIYCSKAPAPSGKGSADTPGSEGKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLEAYLRGCGTAMLHDFSQQVHVIEML
QKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLPKSFRVPYDPGLKAGALVIEKCK
VMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDL
CLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQ
AAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKER
VPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQL
TSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>G3S7D1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gorilla gorilla gorilla|TrEMBL
MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A093PT84|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Manacus vitellinus|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSTLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTTVSTEISGRSDHVWNEELEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGHLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8D2MD93|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zonotrichia albicollis|TrEMBL
MPPGIYCPTEFWSKGENQSIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSEFRAKMCQFCEEKAAQRQQLGWAAWMEYNFPLQLEPAAKGLSS
LQIPNKNIFVNIRFQSGGESFMFQISPWEFPITLMTYAIKKQATVLRPETVQQPEDYTLQ
VNGKCEYLYGNYPLYQFQYIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAVSK
PPPLPKKKPYYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSSSE
VSVCSEPVWRQRLEFDISVRDLPRMARLCLALYAVVEKARKARSTKKKSKKADCPIAWAN
VMLFDYRDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLIITKWNRHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNSEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C4GR37|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
MDGKQIQVSDEEPRVLREENRRRRRKKAITSSSSSSMDQIAVEFVLPTTARGGNSPDTLQ
LEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRLSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQMVPRPQPSDESLQYQRYLNNLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVGNGNILVVIHIGTASQTIKVSID
DPPAQVLASFFTKTANKRALLGIPENMCEEDFVMRVCGRYEYLYGDKPLQNFNWIRQCLK
NGEEIHLVLESPPDPELDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKSFNEEVLWNCWLEFNI
KIKDLPKGARLNLQVVCGNKAHVCLSVHLSGKTKSRLLYYVNLLLIDHRSLLRQGEFILH
MWKMPEKSEESSSSINADKLTSATNPDKASTMAIAILLDKYCYPVVLPKSRDAEGGERGQ
REMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRWGKQEDV
LATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLGDDDVLRYLLQLV
QAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGC
GEDMLQDFRKQVEMTEALQKVTRDIKAMSADKYDVTAQVVFQLRQKLEALQLSGLPKSFR
VPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQDMLI
LQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFKD
EILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHID
FGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLALRHHT
NLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQI
NWFVHLVLGIKQGVEKRST
>A0A833ZV74|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phyllostomus discolor|TrEMBL
MCFNFIMPPAMADILDIWAVDSQIPSDGPIPVDFLLPTGIYIQMEVPREATISYIKQMLW
KQIHNYPMFSLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWIEWLKQTYPPEH
EPSNLENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQISGRLEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNFPLPLPPKKTRIISHVWENNSPFQIVLVKGSKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NASKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLQQMRFLLERALANRRIGQFLFWHLRSEVHIPAV
SIQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLK
QNAYREALSDLQSPLNPCVILSELHVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNG
DDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNS
SNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMV
KKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCE
DAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEDEALKQFKQKFDE
ALRESWTTKVNWMAHTVRKDYRS
>A0A667X3P0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MDQQQVQVSDEEPVVLREESRRRRRKKAITPSSCASMDQITVEFVLPSAARGGSGPDTLL
LEVAANWTVEQVKAQVWLRAVASNLCPDFYQRFSPDHCILLYQKKGSVCEIYDKHQVFQT
LDCIRYWRALKKEVGRIQLVPRPQPTDESLQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSERDAKLYSTDPWLTDRPLTEHLLSKVSNGHILLVIHVGSNSQTIKVSID
DTPVLASFFTKTANKKALLGIPDSVCEADFVLRVCGREEYLYGDKPVQNFHWIRQCLKNG
EEIHLVLETPPDPALDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRK
FRVKVLGIDIPSLPKNPELTVFVEASIFHGQQLLAQERTTSKPLSEEVLWNCWLEFNIRI
RDLPKGARLNLQVTAQKTQRELFSSAQTPNSKASSTKSRLLYYVNLLLVDHRSLLRQGEF
ILHMWKMPEKSEESSSSVNADKLTSATNPDKASSMAVSVLLDRYCFPVVLPKSREAGRDA
AAPDEAEGGERGQREMPNHLRKQFEAIVATDPLHPLSPEDKELLWHFRHECMRHPRAYPK
LLSSVRWGKQEDVLITHRLLERSTAWDSSRLDVGLAMQLLDCHYSDAQVRSMAVRKLETL
GDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIVQSMHYQQ
RYAVLLEAYLRGCGEAMLQDFRKQVEVTEALQRVTREIKAMSADKYDVSAQVVFQLRQKL
ETLQSSGLPDSFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSRDAIGII
FKDGDDLRQDMLILQILLIMESIWETENLDLSLLPYGCISTGNRIGMIEIVKDATTIANI
QQSVVGSTGAFKDEILHQWLRDRCVSEDKKLCCVCVCVCVCVCVCVCVCVCVCAGNLFHI
DFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFHKFQDVCVKAYLALRHH
TNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGWMVQ
INWFVHLVLGIKQGVEKRSA
>A0A8C3T0B9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chelydra serpentina|TrEMBL
MPPAMTDILDIWAVDSQVGADGLISVDFLLPTGTYINLDVPRDATICHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVKEFRSKMRRISEEKLLSLVGLSWLDWLKHSYPPEQEPSIPE
NFQDKLYGGNLVVAIHFDKCQDVFSFQVSPNINPVKLNELAIRKRLTIHGKEEEVDPYDY
VLQISGRLEYIFGDHPLIQFQYIRKCVMNRTLPHLTLVECCSIKKMCEQEMIAIEAAINR
KSSNLPLPLPPKKTRTVTSVWDNSNPFKIMLLKGNKLNTEETAKVHVRAGLFHGTELLCK
PIVSAEIFGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKTINPSKYQ
TIRKAGKVHYPVAWVNTMVFDFKGQLKSGDFLLHSWTSFPDELEEMLNPMGTVRTNPYTE
NATALHIKFQEYSKLPIYYPPFDKILEKAAEIAKSSENAGMAGRGGKKFYIELKEIMERD
PLTQLCENEMDLIWTLRYDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWSKLPPRE
ALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLVERAL
ANRRIGQMLFWHLRSEVHIPAVSVQFGVILEAYCRGSIAHMKVLSKQVEALNKLKTLNSL
IKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELYVEKCKYMDSKMKP
LWIVYNNKMFGGDLLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGCLATG
DHSGLIEAVSASETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSC
AGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFI
HVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLK
DSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6J0I575|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lepidothrix coronata|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GSLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKWEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEPPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRSDWCGVSSWAGPVVLGNRTAEERWRRRGS
QGKA
>A0A663LSF1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Athene cunicularia|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCISSPPRMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFENSLALVEEHTLQLREILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKL
LIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHELF
QYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILE
AYCRGSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHVCMKQETYLEALS
HLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLT
LQMIQLMDILWKQEGLDLSDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQ
LFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMI
LRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRES
WKTKVNWLAHNVSKDNRQ
>A0A852IGW3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tricholaema leucomelas|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSVELISIEFILPTSNKHTKVPEIILLE
IAGNCTVEQMKTQIWMHAIEMSQSTDFYHAFTPDQFILQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVLEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PEMILQSFFTKMAKKKSLMDIPEDHSEMDFVLRICGRDEYITGETRIKDFQWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVVWNIWLEFDIKI
KDLPKGALLNLQLYCGKAQGLSTKTNLQSHESPSSDSKCKTQLLYYVNILLIDHRFLLRT
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPVALPKHRITLD
SQGDRTRAEMPNQLRKQLEEIITTDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKEKCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A851A9S0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sula dactylatra|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPETMVLE
VAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYISGETPIKDFHWVRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPILPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNEAIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C6NGC7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Melopsittacus undulatus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRAKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GPFHIPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPKTA
AKPPPLPKKKPNYGSLWSLEQSFYIQLVQGSKVNADEGMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWQQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQVRNMFFGGHRNSPKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQ
ALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAVNSLKKLT
DHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRF
GLILEAYCRGSTHHMKILMKQGEALNKMKALNDFVKASSLKATKPQTKEMMHVCMKQETY
LEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLR
QDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMQSDTIANIQLNKSNMV
ATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETG
QLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYM
ILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRE
SWKTKVNWLAHNVSKNNRQ
>A0A5F9CVK5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryctolagus cuniculus|TrEMBL
MELESSEQPVVLREDHGRRRRRMKPRSPAASLSSMELIPIEFVLPTSQRDSKTPETALLH
VAGHGNVEQMKGQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKLLHRSPGQIHVVQRHAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
LTPRMAEVASRDPRLYAMHPWVTSKPLPEYLARKITNNCIFIVIHRSTTSQTIKVSADDT
PGNILHSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIRNFQWVRQCLKNG
EEIHLVLDAPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKVRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSAKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASADTPGAESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENAMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYETLKHPKAYPKLFSSVKWGQ
QETVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDLTQQVLVIEMLQKVTIDIKSLSAEKYDVSSQVILQLKQKLENLQNSNLP
TSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTALSKETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEDKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGRL
CQGLPRPSPSHKPADRPLLHDADDRDAPANKQRRHRVHPGRLNDADLRKPRGLSSLETLD
TLRRQLYILASWSSPVPNTSRANENQADHPGKGASLQDPAKTTRLQ
>A0A384DGQ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ursus maritimus|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSVLENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPVSTVFILEAYCRGSVGHMKVLSKQVEALNKLKTLN
SLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKM
KPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLA
TGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTL
SCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYD
FIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A665VYE0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TLPLFPALGEMESYMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRLSEERMQRVQKMSFSEWLQACFSPQLEPA
GTTITDGVNERSADLKVTIHFDQSQDSASLKVSSSCTPTELMEQAVRKWLTTHGPEEEAW
RGQYVLRLSHCLEFLFGDHPLIQYKYIRTCMQAKESPHLTLVHNSTVKAMFDKEMSTIGA
VVNRKSSNPPLPLPPKRRHPTQVQTCVWDVSRPFKIVLVNASKVNAEETAKVQVRAGLFH
GTELLCKPAVSSESSGRSDHMWKENTLEFDISVSDLPRMTRLCFAIYAVMDKVKKQKSTK
NPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDINLHCWSSFPDELEEMLNPIGT
IQTNPYTENATALYIHFPEYSSHPVVFPPFDKILEKAAEIARASDCGTMGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIW
PKLSPRDALELLDFNYPDQYVREYAVRCLRDMSNEELSQYLLQLVQVLRYEPYYDCALTH
FLLERAQGNRKIGHFLFWHLRSEIHMPAVSIQFALILESYCRSCIPHIEILKKQVEALSK
LKSVNELIKLGTTKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPHILLSGIN
VERCRYMDSKMKPLWIVYNNKLMTGDNLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANL
DLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A665UKR0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Echeneis naucrates|TrEMBL
MDGQQIQLSDDEPKFQREEIRRRRRKKAITSSSGTSMDQITVEFILPTVARGGNSPDSLQ
LEVAGNWTVEQVKAQLWLKAVTSNLCPDFYQRFSPDHCILLYQKKGNLYEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESLHYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDPKLYSMDPWVTRKPLPEHLLSKVSNGHILVVIHIATASQTIKVSID
DTPAQVLASFFTKTANKRVLLGIPENMCETDYVLRVCGREEYLYGDKPLQNFNWIRQCLK
NGEEIHLVLETPPDPNQDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTVSMWDCN
RKFRVKVLGIDIPSLPKVPEFIVFIEASIFHGQQLLAQERTTSKTFNEEVLWNSWLEFNI
KIKDLPKGARLNLQVVCGKQPQTPNSKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEK
SEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVSRDVPREMPNHLKK
QFAAIVATDPLHPLSPEDKELLWHFRQECMRDPRAYPKLLSSVRWGKQEDVLTTHHLLER
SSAWDSSGLDVGLAMQMLDCHYSDAQVRSMAVRKLETLEDDDVLRYLLQLVQAVKFEPYH
DSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAYLRGCGEAMLQDYK
KQVEMTEALQKVTREMKTMSADKYDVTAQVVFQLRQKLETLQLSGLPESFRVPYDPGLRA
GGLMIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQDMLILQILLIMES
IWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFKDEILYQWLRD
KCISEDKFQQAVERFLFSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYK
SFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDCCTYVT
>A0A643BPG3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balaenoptera physalus|TrEMBL
MEINDQLQSSDPSTSKSQIGVSFISDYSDPNKDPILEKFTVYQEYYQIVDQCLPSRIARI
RTMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPL
HQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIG
FAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELP
KHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQ
LKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLP
MDCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFD
WFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLMYCLVKDWPPIKPEQAMELLDCNYP
DPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLSYCRACGMYLKHLNRQVE
AMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLE
ECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQ
GLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKG
EIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGY
KRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLG
SGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHAL
N
>A0A674P1C2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNQIKMCQIIVV
IWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQGKYILK
VCGCDEYLLEKHPISQYKYIRSCIMLGRMPNLMLMAKDSLYSQLPTDNFVMPSYSRRIST
ATSYMNGEVAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGIYHGGEQMCDNVNT
QRVPCSNPRWNEWLTYDMYISDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYT
HTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSSSVKYPDMNAVE
DHASRTISREVGLNYTLSGQSNRAARDHILTEGDSEQLRQLTNRDPLSEITEQEKDFLWR
NRYYCMNIPEILPKILLAVKWNSRDEVAKMYCLLKEWPSIRPEQAMELLDCNYPDPMVRH
FAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKS
EMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMR
FLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMSELL
FQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRS
SHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDMAVDLFTRSCAGYCVATFILGI
GDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECVK
TKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKTEQ
EALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A3Q3W676|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mola mola|TrEMBL
MPPGKYGMQEEWEKEGDQGIMMDFLLPTGIFLKFSVSRNDTIKSIKKMVWKNARKEALFE
VLADPDAYVFTCINQTAEREELEEESRRISDVKPFMCVLRLVAREGDRVEKLTNTQISLL
TGRGLHEFEAQKNHEVNEFRTKMRAFCEEKAHERHMLPWQRWMECCFPCELEPRCSGSAK
SKNTKKIFINVKFEACDESFMLQQDPQDVPVALVRSALKKKATVFRSVRQEPEDYTLQVN
GRWEFIYGQHPLCQFKYIFSCLRNGQNPYLTMVHYSTIHKYQEEQGSMCSQVCKSRSSSR
PPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSLE
MAVSYEPLWDQRLEFDINVADLPRMSRLCFALYGFIEKAKKPRGTKKKNKKADCPLAWVN
TMVFDYKDQLKTGEFLLSTWPSVPDDKGGLLNPMGTVEKNPNVDSAAGLLIRFPNIRPYP
LYYPPLDKVLLLKKLCFREHGEICTCYIKICFLKEIMDNKNYTEFFEDEKELLWKLRAEV
RNFYPESLSKLLLITKWSKREDVVQMVSLLRNWPDLPAIQALELLDYSFPDPAVRSFTIR
CLRKLSDDEVLQYLIQLVHVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLKSEIHVA
SVSLRFSLILEAYCRGNIWHIKLLTKQNEALLKMKTLSDIVKTGSQKMTVDDLKLCIRQE
SYLETLSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNPLAQGDMMGIIFKNGDD
LRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSN
SAATAAFNKDALLNWLKSKNPENKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERA
YKILCRNGMLFVNLFAMMKAAGLPELTSFKDIQYLKDSLSLGKSEEEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A674GPG1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Taeniopygia guttata|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGLGV
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGRTPHLTMVHSSAIIAMRDEQTNGITSPPKAA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGTEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAV
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQNPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFRGYCE
RAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A8C4ZBJ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MVPKPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLANIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDEARRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFELVKDPEVQDFRRSILSVCREAMEEREAGGAPSLALYVYPPNVESSPELPQH
IYYKLDKGRLMVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKTRSMHLSAQQLR
LCVLEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCITVGRLPHLMLVSKESLYSQLPES
GFVMPSYSRRTPQPSPCPGGDPTSPPRSLWAFNNLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYMADIPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDTMVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFC
WFNQTVVFPDDQQIEEHANWTISRELGLTYCLSVSAAEVEQLQSLCSKDPLYELSEQEKD
FLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKDWPLMQPESALELLDCNFPEP
VVREFALRCLLQGLSDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFFW
HLKSEMHNKTVSRRFGLLLEAFCRSCGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQK
TQMKFLVEHMSRPDYMDALQGFISPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIM
SELLFTNNQVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIE
VVRNSYTIMQIQCKAGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTRSCAGYCVATF
ILGIGDRHNSNIMVKDNGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLLVISKGSQ
ECTKTKEFDRFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALE
KTQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A8C5BYM5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MDPHTICAASGEEDCGALSRTRRRRKGITSASLSAMDQITIEFILPTTPKNGLSPHTTLL
EVPGNWTVEQVKAQVWLRAVASNFSPDFYHKFSPDHCILLYMKKGTLCEIYDKHQVFQTL
DCIRYWRALKKDVGRISLVFRPPQQDEALRYQRFLNQLIGYDVTDVSNVHDDELEFTRRK
LLTPRRNELQERDPRLYAVDPWLTDRPLRDHLLSKVMNGHLLVVIHIFTTSQTIKVSIDS
TPEQVLASVFAKTANKRALVGIPDDVCESDFVLRVCGRYEYLYGDRPLQDFSWIRRCLKN
GEEIHLVLEKLPDTDLDQVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNR
KFRVKVLGIDIPLLPRNPDLTVYIEASIFHGQQLLAQERTTSKPFMEEVLWNTWLEFDIK
IRDLPKGARLNLQVSCGKTAPPTTSKGSSYQDSPGAGSKSKTRLQYYVNLLLVDHRSLLR
QGEFVLHMWKIPEKGEESSSSVNADKLTSATNPDKASSMAVAVDSGGRGQREMPNHLRKQ
FEAILAKDPLHPLSPEDKELLWHFRHECMRHPRAYPKLLASVRWGRQEDVQAAHAMLERS
SAWDSSGLDVGLALQMLDCNYSDAQVRSMAVRKLETLGGDDVLRYLLQLVQAVKFEPYHD
SALVRFLLKRALRSKRIGHFLFWFLRSEIVQSLHYQQRYAVLLEAYLRGCGDAMLTDFHK
QVEVTEALQKVTREMKAMLADKYDVSSQVVFQLRQTLEALQSSGLPQTFRVPYDPGLRAG
TLMIEQCKVMASKKRPLWLQFKRADPSSLSSDPIGIIFKDGDDLRQDMLILQILLIMESI
WETESLDLYLLPYGCISTGNRIGMIEIVKDAATIANIQQSVVGSRGAFKDEILNQWLRDK
CVNEDRFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNLFHIDFGHILGNYKS
FMGISKEWVPFVLTPDFLYVMGTAGKKSSPHFQKFQDVCVKAYLALRHHTNQLIILFSMM
LMTGMPQLTSKEDIDYIREALTVGRSEEEAERHLLEQIEICREKGWMVQINWFVHLVLGI
KQGVEKRST
>A0A669R8P1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phasianus colchicus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINSIANPPKMA
VKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALLICFPNVAS
HPVYYPSFEQLLELGRNGEQPRSQKLQLKEILERRSHTELYEHEKDLVWKMRHDIRDQYP
QALAKLLTITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAINSLKKL
TDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALR
FGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQET
YLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDL
RQDMLTLQMIQLMDILWKQEGLDLSDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
EKAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A8C1JJT1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
LNSSDDEPPVVRREENKRRRRKMKAFTSTSAVSTDNIAVDFVLPTTNKNSRNPDTLHIDV
TGNWTVEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTLDC
IRYWKALRKEVGKIHLVVRTQPNEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRKLL
TPRKIELADRDPKLYSMDPWITPKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDDTP
VQVLQSFFAKIKKKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKNGE
EIHLVLEHPPDPELDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRKF
RVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIKIK
DLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLLVDHRSLLRQGEFILHMWKM
PEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERGQR
EMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEAVM
ITHHLLERCTVWDRSLLDVGLAIQLLDCHFSDEKVRTMAVRKLETLEDDDVLRYLLQLVQ
AVKFEPYHDSALARFLLKRALRSQRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCG
EAMLQDLRKQVEMTEALQKVTREIKLMSAEKYDVSQQVVLQLRQKLEGLQTSGLPDSFKV
PYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDMLIL
QILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDE
ILSQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDF
GHILGNYKSFMGISKERVPFVLTPDFLYVMSTTGKKSSPHFLQFQNVCLKAYLALRHHTN
LLIILFSMMLMTGMPQLTSKEDIEYIREALTVGCSEDEAKQHFLEQIEICRDKGWTVQFN
WFLHLVLGIKQGVEKRSA
>A0A8C1RWI2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWVESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQNIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKRISEEKMQCMQLMSWGEWLRSCYSMTLEAGSLE
NLIDKHEGVIKITMHYDQSQDTSSLKVSLHCTVTELMDLALKKWQTTHVPEEDIGFRSDY
VLRVSRKLEFLFEDHHLNQCKYIRDCLLTNESPHLTLVHCDVVKAMFEKEISTIGSVLAW
KTSNPPLPLPPKKRLPTQLHTCVWKVHSLFRIHLVKGNKVNAEDAAKIQVRAGLFHGTEL
LCKTAVSSESSSRSEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLN
KYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNP
YTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIME
RDPLSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSP
RDALELLDFNYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLER
AQSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVN
ELIKFGTIKTKTKQAHLKEAMMTCLRQTGFIETLSDLHSPLNPNILLAGVNVERCKYMDS
KMKPLWIVYNNKLLGGDTVDIIFKNGDDLRQDMLTLQILRLMDLLWKEANLEYRIVPYGC
LATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILT
HDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS
>A0A8C1CYW6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFNIYINSCLNCNMPVGHTVERYMFILLTWSLHQSFPKHIYGK
LDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLKMCVQ
EYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLARLPNLMLMSKDSLYSQLPMDNFTM
PSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGIYHGG
EQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAS
GKCQPVDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHFSSPV
KFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTEADIEQLRQLSNRDPLSEIT
EQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDC
NYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIG
HFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKK
DETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWE
NPDIMSELLFQNNEIIFHNGDGKIFFRPNIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRS
SHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNRGEMYDMAIDLFTRSCAGYCVATFILGI
GDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECT
KTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTE
QEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHH
>A0A8C1EJJ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFRAYHSCLSSKLITRNCGRAERI
LDSKIGVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLE
TESVENLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIG
TRSDYVLRVSCRLEFLLEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAIFEKEICTIG
SVLARKASNPPLPLPPKKRTPTQLHTCVWKVHSLFRINLVKGNKVNAEDAAKVNINTSEL
RIITNLTLTFICLLVAHNQYYIKMNTYRLKKQRSTKNTHLNKYQTIRKAGKVHYPIAWVN
TMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQP
VVFPAFDKGRWGDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQ
ALLQIWPKLSPRDALELLDFNYPDQYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYY
DCALSRFLLERAQSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQ
VEALSKLKAVNELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSNLHSPLNPNILLAG
VHVERCKYMDSKMKPLWIVYHNKLLGGDTVGIIFKNGDDLRQDMLTLQILRLMDLLWKEA
NLDLR
>A0A8C1EMA2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWAESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFRAYHSCLSSKLITRNCGRAERI
LDSKIGVLIGKGLHELDALQDQQVKDFRSKMKRISEEKMQRMQLMSWGEWLRSCYSTQLE
TESVENLIDKHEGVIKITMHYDQSQDTASLKVSLHCTVTELMDQALKKWQTTHGPEEDIG
TRSDYVLRVSCRLEFLLEDHPLNQCKYIRDCLLANESPHLTLVHCDVVKAIFEKEICTIG
SVLARKASNPPLPLPPKKRTPTVRTLSVFPALQLIKGALSFVPLAAPNSNAKVIIFLNRF
IKHNTPFILHLVIRRSDKQAVPSQTQAIVKKQRSTKNTHLNKYQTIRKAGKVHYPIAWVN
TMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQP
VVFPAFDKVYPGKAAEIAGGRWGDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVK
WSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVNCLRDMSDDELLQYLLQ
LVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRG
CIPHIEVLKKQVEALSKLKAVNELIKLGTIKTKTKQAHLKEAMMTCLRQTGFIETLSNLH
SPLNPNILLAGVHVERCKYMDSKMKPLWIVYHNKLLGGDTVGIIFKNGDDLRQDMLTLQI
LRLMDLLWKEANLDLR
>A0A8C2BQB5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MEHQASDDEPPVVRREENKRRRRKMKAFTSTSAVSTDHIAVEFVLPTTNKNSKYPDTLHL
DVTGNWTVEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKEVGKIHLVIRQQPNEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDPKLYSMDPWITPKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDD
TPVQVLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAISDFHWIRQCLKN
GEEIHLVLEHPPDPELDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFNEEVLWNTWLEFNIK
IKDLPKGASSMADAILLDKYCYPVALPKSKDSPDSEMEGERGQREMPNHLRKQFEQIIAT
DPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEAVAITHCLLERSTVWDRSS
HDVGLALQLLDCHFSDENVRTLAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALARFL
LKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGEAMLQDLRKQVEMTEA
LQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGLPDSFKVPYDPGLRAGALVIEQC
KVMASKKKPLWLQFKRADPTTLSRDTIGIIFKDGDDLRQDMLILQILLIMESIWELESLD
LSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDEILSQWLSEKCVNEDKH
QQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFMGISKE
RVPFVLTPDFLYVMCTTGKKSSPYFLQFQVRSFCFTC
>A0A8C1CY67|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MCVCVCVCVCICVCVFVCVCIPNGILVSLECLREAPLTSIKQQLFSEAHKYPLHHLLQEE
SCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFAIGMPI
CEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSADLPQHIYSKL
DKGRLIVTIWVIVSPSNSKQKYTLKIAHDSLPEQLIAEAIRKKTRSMHLSAQQLRLCVQE
YQGQEGCNLVQELRLDDARFAADFRLDRVLCSYHIINSLSSETSTICLPASF
>A0A669P016|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phasianus colchicus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRMTSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKDRCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L2EGJ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anthoscopus minutus|TrEMBL
MPPGIYCPTEFWSKGEHQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSMQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQNSCITSPPKAA
SKPPPLPKKKPNYGTLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
SSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
AAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGLIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A1A8S7B5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius rachovii|TrEMBL
MPPGKYGMQEEWEKEGDQNILMDFLLPTGIFLKFPVPRNDTIKNIKKMVWRNAKTEALYF
GLGDPEGYVFTCINDTAEREELEEESRRISDVRPFMCVLRLVAREGDRGEKLTNSHISSL
IGKGLHEFEAQKNHEVDEFRSKMRTFCEEKALERHNLPWQQWMEYSFPCDLEPCCSPPVH
GGTKSKHTKKLFINVKFEACDESFMLQQDPLDIPVALMKSALKKRATVFRSVRQEPEDYT
LQVSGRWEFIYGDHPLGQFKYIFSCLRNGQNPQLIMVHHSTISKYQEEQGQLCSQVGKIR
SQSRPPPLPMKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQKLDFDINVSDLPRMSRLCFALYAVIEKTKKPRGTKKKNKRADCPI
AWVNTMVFDYKDQLKTGEFILSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPPLDKMIVMERNGDAVFATKVERMRLKEIMDNKNSTEFFEDEKELLWKLRTEV
RDCYPESLSKLLLITKWSKREDVVQMVSLLRNWPDLPAIQALELLDYSFPDPAVRSFTIR
CLRKLSDNELLQYLIQLVQVLKYESYLDCDLATFLLERALSNRRIGHFLFWHLRSEIHVA
SVSLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDIVKSGCQKMTVEDLKLCIRQE
SYMEALSNLMSPLNPSIVLVELCADKCRFMDSKMKPLWMMYKNPSEHADMVGIIFKNGDD
LRQDMLTLQMIHLMEDLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKHSDTIANIQRNNSN
SAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRE
TGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEWA
YKILCKNGTLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEDEALKNFKVKFNEAL
RESWKTKVNWMMHSLAKDNRP
>A0A8C6NS94|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius furzeri|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPHGMILTLECLREATLVTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFKAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSSALYVYPPNVESSAELPRH
IFNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTQEQLK
MCVQEYQGKYILKVCGCDEYLMEKYPISQYKYVRSCIMLGRMPNLMLMTKDSLYSQLPTN
NFTMPSYARRISTATPYMNGETATKCLWTINGTLRIKILCATYVNVNIRDIDKGSGEEAV
KCLNVYRQPSLCSTPLPQLQAEHCPLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLL
NPIGVTGSNPNKETPCLELEFDHFGSPVKFPVMSQVEEHANWNFSREHGFNYSHTGLSNR
VARDNPLTDSDNEQLRQVCNRDPLSEITEQEKDFLWRHRYHCVNIPEILPKILLAVKWNS
RDEVAQMYCLLKDWPAIKPEQAMELLDCNFPDPMIRDFAVKCLEKYLTDDKLSQYLIQLV
QVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACG
MYLKHLSRQVEAMEKLINLTELLKQEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLN
PAHTLGNLRLEECRMMSSAKRPLWLNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQI
IRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHA
LHQWLKDKNKGEMYDQAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGH
FLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHAN
LFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMD
WIFHTIRQHAMN
>A0A2K6SFQ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Saimiri boliviensis boliviensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWSEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3Q0GZM5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alligator sinensis|TrEMBL
MPPTVTDILDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLLEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSRI
GVLIGKGLHEFDALPDPEVKEFRTKMRRISEEKNHSLVSLSWMDWLKHTYPPEQEPSIPE
NFQDKLYGGNLVVAIHFDNCQDVFSFQVSPNINPIKLNELAIRKRLTIRGREDEEINPSD
YVLQVSGRLEYVFGDQPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCDQEMIAIEAAIN
RKSSNLPLPLPPKKTRTATLTQSVWDISNPFKIILLNGNKLNTEETTKVSVRAGLFHGTE
LLCKPIVSTEVSGRSDHVWNETLEFEVNVCDLPRMARLCFAVYAVMDKMKTKKSTKTMNT
AKYQTIRKAGKVHYPVAWVNTMIFDYKGQLKTGDLILHSWSSFPDELEEMLNPMGTVQTN
PYAENATALHIKFQEYSKLPIYYPPFDKILEKAAEIAKSSDSAMAGRGGKKFYVVLKEIM
ERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWTKLP
PREALELLDFNYPDQYVREYAVGCLKLMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLE
RALANRRIGQVLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLSKQVEALNKMKTL
NGLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHIERCKYMDSK
MKPLWIVYNNKMFGGDFVGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGCL
ATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTY
DFIHVIQQGKTGNTEKFDRFRQYCEEAYLILRRHGNLFITLFALMLTAGLPELTSIKDIQ
YLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A212CLH3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cervus elaphus hippelaphus|TrEMBL
MELENHEQPVVLREDTCRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLHYWKVLHRSPGQIHLVQRRAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEEDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCCKAPVLSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKLSSTKPQPMAEKDRMRMPEASAPQSWHKGKFCCYSQQFLH
SVLPPEFPQATSSQLLKPEACAETAWSGHWERPFI
>A0A1U7RDR5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Alligator sinensis|TrEMBL
MLPGIYCPVEFWSKEENQNIQVDFLLPTGIYLSLPVSCNASLGTIKEVVWQHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVSDPEVSDFRTKMRQFCEERAAKRQQLSWMAWMEYSFPLQLEPLAKGLGT
SPLHVPHKNIFVNVMFESGGESFTFQISPREYPITLMSYAIKKQATVFRHQTVESPEDYT
LQYIRSCLHQGLMPHLTMVRFSTIIAMRDEQTNCIAHPPKMGAKPPPLPKKKPNSGSLWS
LEQPFYIDLVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSSSEVNVCSEPVWKQRLDFD
INICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKAGECC
LHMWSSFPDEKGELLNPMGTVQSNPNTESAAALVICFPNVSVHPVHYPAYEQLLDLGRNG
EHSRATLDDPEEKQQLKEILERRSHTELYEHEKDLMWKMRYHIRDQYPEALAKLLIITKW
NKHEDVAQMISLLHTWPELPVLNALELLDFSFPDRYVGFFTINSLKKLTDEELFQYLLQL
VQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGS
THHMKVLMKQGEALNKMKALNDFVKVSSQRATKPQTKEMMHVCMKQETYLEALSNLLSPL
NPNIILAEVCVEQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQL
MDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALL
NWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFL
GNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRDYCEKAYMILRRHGLLFLH
LFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAH
NVSKDNRQ
>A0A7K9WL01|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhipidura dahli|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGPGT
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQTNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7K6CEC3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ptilonorhynchus violaceus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSNFSSMEMISIEFILPTSNKHTKVPEMILLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQQPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSILDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A668UHA4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MPPAMTDLLDIWAAHSPLAGHAPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDALNDQEVKDFRSKMFRISEERMQQIQMMTFSEWVQACYSPQLEPA
AVTAITAGVNDAPVDLKVIIHFDQSQDSASLKVSLSCTPNELMEQALRKWLTTHGSEDAV
WRGQYILRVSQCLEFLGGDHPLIQYKYIRSCLQAKETPHLTLVHTSAVKTMFDKEISAIG
AVVSRKSSNPPLPLPPKRRAPTQVQTCVWDVPKPFRIVLVKGSKVNAEETAKVQVRAGLF
HGTELLCKPAVSNESSGRSEHTWKDNTLEFEISVCDLPRMTRLCFAIYAVMDKVKKQKST
KNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPEYSSHPIVFPPFDKVTQHSIGRGVKKFYMELKEIMERDPVS
QLCENEKDLIWTLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALE
LLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQRNR
QIGHFLFWHLRSEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQVEALSKLKSVNELIKL
GTIKNTRSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDINVEKCRYMDSK
MKPLWIVYNNKLLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCL
ATGDRTGLIEVVSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTH
DFIHVIQQGKTGNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQ
YLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A668VZ60|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
YTTGQPCSAVVMLNTESRRRRRKKAITSSCSNSMDQITVEFVLPTAARGGSGSDTLQLDV
AGNWTVEQVKAQVWMKAVTSNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQTLDC
IRYWRALKKDVGRIQLVPRPQPSQESVEYQRYLNYLIGYDVTDVSNVHDDELEFTRRKLL
TPRRIELSERDPKLYSMDPWVTCKPLPEHLLSKINNGHILVVIHIGTASQTIKVSIDDTP
TLVLVSFFAKTSNKRALLGIPDNVCETDFVLRVCGREEYLYGEKPLENFNWIRQCLKNGE
EIHLVLEMPPDPDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKF
RVKVLGIDIPSLPKVPEFIVYIEASIFHGQQLLAQERTTSKTFSEEVLWNCWLEFNIKIK
DLPKGARLNLQVICGKQPQIPNSKGSSYQESTAGRKTKSRLLYYVNLLLIDHRSLLRQGE
FILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRD
WAVGGEDAEGGERGQREMPNHLKKQFEAIVGTDPLHPLSPEDKELLWHFRHECMRVPRAY
PKLLGSVRWGKQEDVLATHRLLERSSAWDTSGLDVGLAMQLLDCHYSDAQVRSMAVRKLE
TLEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSKHY
QQRYAVLLEAYLRGCGENMLQDFRKQVDMTEALQKVTREIKTMSADKYDVTPQVVFQLRQ
KLENLQSSGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADSTTLSKDPIG
IIFKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIEIVKDATTIA
NIQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHN
DNIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKF
QDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLL
DQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A668RZU3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis aureus|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVDLDTELVPETIR
>A0A8D0AIE0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MDGQQIPVSDQEPKALREDTRRRRRKKAIMSSSCTSMDQISVEFVLPTAARGGNNPDTLL
LEVAGNWTVEQVKAQVWLKAVTLNLCPDFYQRFSPDHCILLYQKKGNVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLAPRPQPSDESQQYQRYLNYLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIQLADRDAKLYSMDPWVTRKPLPEHLLSKISNGHILVVIHIGTASQTIKVSID
NTPAQVLVSFLAKTANKRSLLGIPDNMCEADFVLRVCGRYVGVIHWICLKNGEEIHLVLE
APPDTDLDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRKFRVKVLGI
DIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKTFNEEVLWNCWLEFNIKIKDLPKGAR
LNLQVVCGKQSQTPNSKGSSAYQDNIKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPEK
SEESSSSINADKLTSATNPDKASAMAVAILLDKYCYPVVLPKSRDVGRDAATGCEEAEGG
ERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRWGK
QEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETLEDDDVLRYL
LQLVQAVKFEPYHDSALVRFLLKTALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVLLEAY
LRGCGEDMLQDFRKQVEMTEALQKVTREVKAMSADKCDITAQVVFQLRQKLETLQSSGLP
ESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLRQ
DMLILQILLIMESIWETESLDLCLLPYGCISTGNKIGMIETVKDATTIANIQQSVVGSTG
AFKDEILCQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGNL
FHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQIEICREKGW
MVQINWFVHLVLGIKQGVEKRST
>A0A8D0CQB9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMLLTLECLREATLITVKHELFKEARKYPLYN
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESCAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPCAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKCFQHDLNNRLAR
DNPLTDTDNEQLRQVCNRDPLSEITEQEKDFLWRHRQHCVNMPEILPKILLAVKWNSRDE
IAQMYCLLKDWPAIKPEQAMELLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVL
KYEQYLDNPLARFLLKRALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYL
KHLSRQVEAMEKLINLTDLLKQEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAH
QLGNLRLEECRMMSSAKRPLWLNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRI
MENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQ
WLKDKNKGEMYDQAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLD
HKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFI
NLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIF
HTIRQHAMN
>A0A091SMT8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pelecanus crispus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGRIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKMAKNHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNGEEIHLVLDN
PPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRKFRVKIIGID
IPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKIKDLPKGALL
NLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRSGEYVLHMWK
IPGKGEEQGSINADKLTSATNPDKENSMAISVVLDKYCHPIALPKHRITSDPQGDRTRAE
MPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVKWGQQEIVAK
TYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVLHYLLQLVQA
VKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVILEAYLRGCGK
AMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIVQLRQKLEKLQSSKLPESFRVP
YDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQ
ILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEI
LNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFG
HILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAYLALRHHTNL
LIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRDKGWTVQFNW
FLHLVLGIKQGVEKHSA
>G9KGM0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mustela putorius furo|TrEMBL
TMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLH
QLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGF
AIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPK
HIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQL
KLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPM
DCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTG
IYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDL
>H3AE22|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Latimeria chalumnae|TrEMBL
MEQSEDYNQPVVMRKENARRRRMKAHTAKSRMPLMEQITVEFVLPTSNKLTKTPETILMD
IPGNCTVEQMKTQVWMKAIEKSLNLEFYQKFTPDQCILQYQKKGQWYEIYDKHQVIQTLD
CILYWKALQKDIKKIYMVQKPKITEEAMKFQKQLNSLIGYDVTDVSNVHDDELEFTRRKL
VTPRLIEIANRDPKLYSMNPWFKSKPLPDYLLNKISNNNIFIVIHRGTTSQTIKASLDDT
ADMILQNFFTKMANKMALLNIPEDCSETDFVLRVCGRDEYIIGETQLKDFHWIRQCLKKG
EEIHLVLDSPPDPKEDEVQKEEWPLIDDCTGVTGSHEQLTIEGKDHEKVFTISLWDCDRK
FRVKIVGVDIPILPRNTDLTIFIEASIQHGQQLLAQQRTTSKPFTEEVLWNTWLEFDIKI
KDLPKGARLSLYVYCGKAHTLSTKTGLQSQDCGSPDPKCKNQLLYYVNLLLIDHRSLLRQ
GEYVLNMWKFPDKGEEQGSINADKLTTATNPDKKLSMAISVILDKYGYPIALPKCRGLSD
AEGEKSKPEIPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRHEIITHPEAYPKLLSSVK
WGCQDTVLKIHQLLLKQDAWEKSPLDVGLAMQLLDCNFSDEKVRTMAVKKLEKLGDDDVL
RYLLQLVQAVKFEPYHDSALARFLLKHALRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFMKQVQITEVLHKVTMEIKSLSAEKYDVSSQVIGQLRQKLEKLQNC
KLPESFRIPYDPGLRAGTLVIDKCKVMASKKKPLWLEFKCADSTALSNETIGIIFKHGDD
LRQDMLILQILRIMDSIWDAESLDLCLLPYGCISTGNKKGMIEIVKDATTIAKIQQSTVG
NTGAFKDEVLSHWLREKCLIEEKFQLAVERFVYSCAGYCVATFVLGIGDRHNDNIMITES
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLHVMGTSGKKTSLHFHKFQDVCTKVY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTIGKNEEAAKKHFLDQIEICRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A3P8PT21|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astatotilapia calliptera|TrEMBL
MVPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMMKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKFPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDILVCGKVALSLWPVPHGLEDLLNPIGAAGSNPNKETPCVELEFS
WFNQIVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSSGDAEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGIQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLMLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
>A0A4W3JS83|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPAMTDPLDIWAVDSQIPADNSITVDFLLPTGIYIQLDVPREATIDQIKMLLWRQAQTY
PLYTVLGEKDSYMFQCVNQSAVHEELEDESRRLCDVRPFLPVLKLVARNCNRSERLLDSK
IGVLIGKGLHEFDALTDPEVREFRSKMRMFNEEKMLKLQGLSWMDWLKHSFPPELESTAF
NNFEDKLPKENLVVAVQFDSCQENFSFQISPNLNPLDLNELAIRKQLTIHGKENEEFNPR
DFVLRVSGKQEYLFGEQPLIQFRVCSAYEQQMATNVWDINSPFKMLLIRGNKINADEAVR
VQVRAGIFHGTELLSKSVVSTEVSGKNDLVWNEILDFEINLCDLPRMSRLCFAVYGVMDK
VKKQKSTKNASKYQTIRKAGKHYPIAWVNTMVFDFRAQLKSGDLDLHCWSSFPDEMEDML
NPMGTVQTNPYSENAASLHIQFQEYSKSVIYYPAFDKVSLYYIFHTIDFYLYLSRPFSPS
SLFRHSMMSTSAPITALVPYPSILLNLLVSGNCLYKYSYLIDFEMDRLCNRSGTDVLHVR
QERLRRYFLKEIMERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDVA
QLQALLQIWIKLCPRDALELLDFNYPDQYVREYAVKCLKEMSDEELSQYLLQLVQVLKYE
PYFDCALSRFLLERAQANRRIGHFLFWHLRSEMHLPATSLQFGLILESYCRGSFTHIKEL
SKQMEALSKLKAINNLVKLSYLKVTRTKVKEVMNTCLKQPVYTEALSDLQSPLNPSVILS
KLNVDKCKFMDSKMKPLWILYNNKMSGGEPVGIIFKNGDDLRQDMLALQILRLMDMLWKE
AGLDLRIVPYGCLATGDKSGLIEVVSASETIANIQLTNSNVAATAAFNKDALLNWLKEKN
TGDALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRETGQLFHIDFGHILGNFKSKF
GIKRERVPFILTHDFIHVIQQGKPGNAEKFGRFRQCCEEAYLILRKNGNLFITLFALMLT
AGLPELSSVKDIQYLKDSLALGKSDDEALKQFRQKFDEALRESWTTKVNWMAHIVAKDNR
S
>V9K9S2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPGMQYHQDLWSEDENPDVEVEFLLPTGIYLNFYVPRSSTISYIKKLLWQQAQQQPLFH
TLNEPDAYVFTCINHTAEREELEDERRRLCDVRPFLPVLKLVAREGDRAEKLINSQISLL
IGKGLHEFDCMQDYEVAEFRLKMRQFCEDKESERLRMSWQDWMEYSFPRELEPIQEAPDN
NMIRTLSNRNIVINVKFQYNEESFSFQISPQSHPGTLMQMAVKKKATVFRHKTVEHTEDY
TLQVNGTEEYIYGNYPLGQFKHIWNCMYSSSTPHLTMVHSSTINSLKGEQSNSIAQVPKS
RTYSKPPPLPIKKQSGITLWNLDQPFTITLMSGSKVNADEGMKLVVQAGLFHGSEMLCKT
VSSHEVSVCSEPAWDQALEFDIHFSDLPRMTRLCFALYGVIDKAKKARSTKKKSKKADCP
IAWVNTMVFDYKDQLKTGDVWLHMWPSIPDEKGELLNPMGTVQGNPNTDSAAALYVRFRN
MGSYPIYYPSFDKILELGKNGDHSKASPTEQQQLKEIMERKSCTEFFEDEKDLVWKLRWE
SRDHYSDALAKLLSITKWNKHEDVAQMIYLLQSWPELPALHALELLDYSYPERYVRSFAI
NCLKNLSEEELFQYLLQLVQVLKYEPYLDSELTKFLLNRALANKKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGNNYHMKSLMKQCESLKKMKALNDFVKSSSQKTTKPKTKEALHL
FMRQEAYMEALSNLHSSLNPSSLLTDLWVDKCKFMDSKMKPLWIVYKNEKYDGDPMGVMF
KNGDDLRQDMLTIQMIQLMDVLWKRQGLDYRMIPYACLSTGDKTGLIEVVSRSETIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRENGQLFHIDFGHFLGNFKSKFGINRERVPFILTHDFVHVIQQGKTSNSEKFERFRK
YCEHAYMILRKHCPLFINLFALMRAAGLPELSSSKDIQYLKDSLALGKTEEEALKHFKMK
FDEALRESWKTKVNWMAHNVAKDNRS
>D3ZFJ0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rattus norvegicus|TrEMBL
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLD
CLRYWKMMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIVNNCIFIVIHRGTTSQTIKVSADDT
PDTILQSFFTKMAKKKSLMNIPESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRNEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPSLSSKASVETPGSESKGKAQLLYYVNLLLIDHRFLLRHGGY
VLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGKAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSSLP
ESFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKRADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWEAESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVRAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALMVGRSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7L2ZY17|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Prunella fulvescens|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQALWQQAQHEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKLINSQISLL
IGKGLHEFDSVQDPEVSDFRAKMCQFCEERAARRQQLGWAAWMEYNFPLQLEPVAKGLGT
GSLHIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGRTPHLTMVHSSAILAMRDEQTNCITSPPKAA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGPAMLCKTVSS
AEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVVEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLVITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRVK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6I8SWB3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus tropicalis|TrEMBL
MQRSISLYEEIILDAAPIWHEREGRLCQARNGFPSLKTLMLLWKHAQSYPLFHLLLEIDS
YMFQCVNHNAVHEELEDETQRLCDVRPFLPVLKLVSRSCNPAEKLDSKIGVLIGKGLQEF
DALKDNEVMEFRSKMRSISEAKIQSLLGLTWVEWLKRTFPPELEPSIQDNIQGKLYGGNI
VVAIHFENCQDVFSFQVSPNMVPVKVNELAIRKRLTIHGREAEEVDPEDFVLQVNGRLEF
VFGDHPLIQFQYIRNCVMNKALPHLTLVECCNIKKLFDQEMSEIEHAVRRKSSMHPALPM
PLPPKKRGASMKTLNMRDIVWNIVQPYKIILSKGSRLNTEDSVLVRAGLFHGTELLCKPT
MTPEVQGKNDHVWNETLEFEINVCDLPRMARLCFAIYAVLDKPRNKNKTKYQTIKKSGKM
HFPVAWVNTMVFDYKGQLRSGDHVLHCWSSFPDELEEMLNPMGTVRTNPYTENTTTLHIK
FHDYSKEPISYPPFDKILEKAAEIARNSDSLSTSGRGGKKLNIELKEIMERDPLCQLCEN
EKDLIWTLRYDCRENFPGSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPRDALELLDFN
YPDQYVREYAVNCLKPMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLQRALDNRRIGQF
LFWHLRSEVHNPAVSVQFGLLLEAYCRGSVAHMKVLSRQVEALNKLRTLNGLIKLNAVKL
SKVKNKDNMHTCLRENAYKEALMHIQSPLNPSITLSELVVEKCKYMDSKMKPLWIVYNNR
GFGSDSLGIIFKNGDDLRQDMLALQLLRLMDMLWKEAGLDLRIVPYGCLATGDRCGFIEV
VSAAETIADIQLDSSNLAAAAAFNKDALLNWIKECHSGDDLERAIEEFTLSCAGYCVATY
VLGIGDRHNDNIMVRKTGQLFHIDFGHILGNFKSKFKIKRERGPFILTYDFIHVIQQGKP
GNTEKFGRFRQCCEDAYLILRRNGNLIITLFALMLTAGLPELSSVKDIQYVKDSLALGKK
EEDALKQFRQKFDEALKESWTTKVNWMAHTMRKDYKA
>A0A8D2Q0B8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zosterops lateralis melanops|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C9L4B8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pavo cristatus|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHTY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRSKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
NFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEIDPAD
YVLQVSGRLEYVFGDHPLIQFQYIHNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEVAIN
RKSSNLPLPLPPKKTRSVWDICSPFKIILLKGNKLNTEENAKVHVRAGIFHGTELLCKTI
VSTEISGRSDHAWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKSMNPSKYQTI
RKAGKVHYPVAWVNTMVFDYKGQLKNGEFVLHSWSSFPDELEEMLNPMGTVQTNPYTENA
TALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAVSVC
>A0A1S3APW5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Erinaceus europaeus|TrEMBL
MPHLEPLVTLALTSAKGSRNRGEKSQRRQHWCKCTPRIPAGCHSSNAWGRGCIISEPSSY
GWSPTGSCFQTDKGQKCLDSPGVATAVLWHRAQYEPLFHMLSDPEAYVFTCVNQTAERQE
LEDEQRRLCDIQPFLPVLRLVAREGDRAKKLVNSQISLLIGRGLHEFDSLRDPEVNDFRA
KMRQFCEEAAMRRQQLGWEAWLQYSFPLQLEPSAHSWGLSTDRALLVNVKFEGSEESFTF
QVSTKDPPLALVACALRKKATVFRQPLVEQAEDYALQVNGKHEYLYGTYPLCQFQYICSC
LHSGLTPHLTMVHSSSILAMRDEQSKPAPQVQKPPRSKPPPIPVKKPSCTSLWSLEQPFC
IQLIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSSEVNVCSEPVWKQQLEFDINVCDL
PRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGECCLYMWPS
VPDEKGELLNPTGTVRSNPNTESTAALLICLPEVAPHPVYYPALDKILELGRHGEQGRFT
EEEQLQLRELLDRRGSGELYEHEKDLVWKMRHEIQEHFPEALARLLLVTKWNKHEDVAQM
LCLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELSQYLLQLVQVLRYESY
LDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPAVALRFGLIMEAYCRGSTCHMKALMR
QTVLGMAALGGSFVVFDGMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFN
KDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHID
FGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGYCERAYTILRRHG
PLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKV
NWLAHNVSKDNRQ
>A0A8J7NU08|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Atractosteus spatula|TrEMBL
MPPAVMDTLDIWAVDSQLTNDVCVAVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFSFLGEMESYMFECVNQSAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAEKLLDSK
IGVLIGKGLHELDALQDPEVKDFRTKMFRISEDKMQKLQMMTWMEWLQCYFSPVLDSTVP
DGIQDKLNVTMHFSHSQDTASIAISPYMTPNDLTEQAVKKWLTTHRSEEEVNSSDYVLRV
STRLEFLFGEHPLIHYKYVKTCMMCNESPHLTLVECSTVKEMFEKEISAVGTVVNRKSSN
PPFPLPPKKRGVSQISTCVWDVAEPFRITLIKGSKVNAEETVKVQVRAGLFHGTELLCKP
AVSSETCGKNEHVWNKTLEFDINVCDMPRMTRLCFAVYAVMDKVKKQKSTKNIHATKYQT
IRKAGKVHYPIAWVNTMVFDYRGQLKTGELILHGWSSFPDELEEMLNPIGTVQTNPYTEN
ATALHIHFQECTKSTVIYPPFDKILEKAAEIARGSDCMPMVSRGSKKFHIELKEIMERDP
LSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWNKHEDMAQLQALLQIWPKLSPRDA
LELLDFNYPDQYVREYAVNCLRDMSDEELSQYLLQLVQVLRYEPYYDCALSRFLLERAQA
NRKIGHFLFWHLRQSEIHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALCKLKAVNEL
IKLGTLKNARNKTKEAMLTKEAMMTCLRQTGFAETLSDLQSPLNPSILLSGIHVERCRYM
DSKMKPLWVVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDMLWKEANLDLRIVPY
GCLATGDRTGLIEVVSASETIANIQLTSSNVAATAAFNKDALLNWLKEKNSGDALDRAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFI
LTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRKNGNLFITLFALMLTAGLPELTSVK
DIQYLKDSLALGKTDEDALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C5TUH3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Malurus cyaneus samueli|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVLWKHAQYERLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGPGS
LHIPTKNIFVNVRFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQRPEDYTLQ
VNGKCEYLYGNYPLYQFQHIRRCLQRGRTPHLTMVHSSAIIAMRDEQTNCIASPPKAASK
PPPLPKKKPNYGSLWSLEQPFYIELLQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSE
VNVCSEPVWKQRLDFDINICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAWVN
VMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAAHP
VYYPSFEQLLELGRNGEQPRAAPEDSEEKQQLKEILERRSHTELYEHEKDLVWKMRYDIR
EQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHVPA
VSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
VRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYC
ERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKSDEEALKHFRLKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A7K7WKX9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothocercus julius|TrEMBL
MPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWQHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRIKMRQFCEERAAKRQQLSWAAWMEYNFPLQLEPLAKGFGT
GPLQTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIANPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSIAS
HPVYYPSFEQLLELGRNGEQPRTALEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
VRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDGELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYLEALSHLQSPLNPNIILAEVCVEQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRS
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALAKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A4W4H0Z1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Electrophorus electricus|TrEMBL
MEQGSDDEPPIVLRKEDKRRRRKMKAFTSNSCMEMDHLAMEFLLPTTNKITKNPDMLQLS
VTGNWTVEQVKTQVWLRAVTTNLCPEFYQKYSPDHCILLYQKKGSWCEIYDKHQVFQTLD
CIRYWKALKKDVGKIHLVLRPQPSEESIQYQKFLNYLIGYDVTDVSNVHDDELEFTRRKL
LTPRKIELADRDPKLYSVDPWITTKPLPDYLLSKITNSHILVVIHKDTSSQTIKVSIEDT
PVQVLHSFFLKTANKRALLGLPEDVSESDFVLRVCGREEYIFGNYAIKDFHWIRQCLKSG
EEIHLVLETPPNPDQDVVPKEDWSQVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNRK
FRVKILGIDIPVLPRNSELIVFVEASIYHGQQLLAQERTLPKPFTEEVLWNVWLEFNIKI
RDLPKGSRLNLQVSCGKAQTQASKDSTGHDGRNKGRLLYYVNLLVVDHRSLLRQGDFILH
MWKMPEKTEDNSSVNADKLTSATNPNKTTSMAITVLLDKYCYPVALPKSRDSRESSDGEE
ERGNREMPNHLRKQFEQIVVTDPLHPLSIEDKELLWHFRQECTRLPTAYPKFLGSVKWGK
QEDVMITHRLLERSTAWERSSLDVGLAMQLLDCHFSDANVRTMAVRKLETLGDDDILRYL
LQLVQAVKFEPYHDSALARLLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAY
LRGCGEAMLQDFRKQVEITEALQKVTRDIKAVSAEKYDVSPQVVFQLRQKLESLQVSGLP
NSFKVPYDPSLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLTNDSIGIIFKDGDDLRQ
DMLILQILLIMESIWDTESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTG
AFKDEILNQWLRDRCVSEDKFQQAVERFVYSCGGYCVATYVLGIGDRHNDNIMITESGNL
FHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMGTTGKKSSPNFLQFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSTEDIEYIREALTVGCSEDQAQKHFLDQIEICRDKGW
TVQFNWFLHLVLGIKQGVEKRSA
>A0A5E4AM16|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Marmota monax|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSLGA
GNASRVPSRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQLLVEQPEDY
TLQVNGRHEYLYGSYPLCQFQYICSCMHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKP
RTKPPPIPVKKPSSVSLWSLEQPFCIDLIQGSKVNADERMKLVVQAGLFHGNEMLCKTVS
SSEVSVCSEPVWRQRLEFDINVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIA
WANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGSVRSNPNTESAATLVICLPEVA
PHPVYYPALEKGRPRPGSSQQGHLLQILELGRHGERGRATEEEQLQLREILERRGSGELY
EHEKDLVWKMRHEVQERFPEALARLLLVTKWNKHEDVAQVGGEGHGAELGVEG
>A0A1L8G4U9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus laevis|TrEMBL
MPPITDHTDIWTADTPLPPDICVDVLLPTGIYVQMEVPRNASISYIKQLLWKHAQSYPLF
HLLLDIDSYMFQCVNQTAVHEELEDETRRLCDVRPFLPVLKLVSRSCNPADKLDSKIGVL
IGKGLQEFDALKDNEVIEFRCKMRSISEGKIQSLLGLTWVEWLKRTFPPELEPSVQDNIQ
GKLYGGNIVVAIHFENCQDVFSFQVSPNMAPVKINELAIRKRLTIHGRETQEADPEDYVL
QVSGRLEYVFGDHPLIQFQYIRNCVMNKTLPHLTLVECCNIKKLFDQEMSEIEHAVRRKS
SMHPALPMPLPPKKRGASMKTVNMRDIVWNIVQPYKIVLSRGSRLNTEDNVLVRAGLFHG
TELLCKPTMSSEVQGKNDHVWNEILEFDINVCDLPRMARLCFAIYAVLDKPRNKNKTKPS
NPKYQTIKKSGKMHFPVAWVNTMVFDYKGQLRSGDNVLHCWSSFPDELEEMLNPMGTVRT
NPYSENTTTLHIMFHDYSKGPISYPPFDKILEKAAEIARNSDSLSTSGRGGKKFNIELKE
IMERDPLCQLCENEKDLIWTLRYDCRENFPGSLPKLLLSVKWNKLEDVAQLQALLQIWSK
LPPRDALELLDFNYPDQYVREYAVNCLKYMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LQRALDNRRIGQFLFWHLRSEVHTPAVSVQFGLLLEAYCRGSVAHMKVLSRQVEALNKLR
TLNSLIKLNAVKLSKVKNKDNMHTCLRENAYKEALTHIQSPLNPSITLSELVVEKCKYMD
SKMKPLWIVYNNRGFGSDSLGIIFKNGDDLRQDMLALQLLRLMDMLWKQAGLDLRIVPYG
CLATGDRCGFIEVVSAADTIADIQLDSSNLAAAAAFNKDALLNWIKECNSGDDLERAIEE
FTLSCAGYCVATYVLGIGDRHNDNIMVRKTGQLFHIDFGHILGNFKSKFKIKRERGPFIL
TYDFIHVIQQGKPGNTEKFGRFRQCCEEAYLILRRNGNLIITLFALMLTAGLPELSSVKD
IQYVKDSLALGKTEEEALKQFRQKFDEALKESWTTKVNWMAHTMRKDYKA
>A0A6P7IL02|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Parambassis ranga|TrEMBL
MPPGKYGMQEEWEKEGDLDINMDFLLPTGIFLKFPVSRNDTIKTIKKMVWKNARSEALFS
GLGDPDGYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKDHEVNEFRTKMRTFCEEKAQERQSLSWQQWMEYSFPCDLEPCCSAKSK
NTKKIFINVKFEASDESFMLQQDLQDLPVALMKSALKKKATVFRSVRQDPEDYTLQVHGR
WEFIYGKHPLCQFKYIFSCLRNNQNPHLTMVHHSTISKYQEEQGMMCNQVYKSRSLSRPP
PLPVKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSSEVT
VCSEPLWDQKLEFDINVSDLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVNTM
VFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIHFPNIRPHPLY
YTPLDKKSDMEKNGDIVFASKEEYMKLKEIMDNKNYTEFFEDEKELLWKLRTEIRDHYPE
SLSKLLLVTKWNKREDVIQMVSLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLRKLS
DDELLQYLIQLVQTLKYESYLDCDLTTFLLERALSNRQIGHFLFWHLRSEIHVASVSLRF
GLILEAYCRGNIHHIKLLTKQNEALVKMKALSDIVKSGSQKMTVEDLKLCIRQESYLEAL
SDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNPLAQGDMVGIIFKNGDDLRQDML
TLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNNSNSAATAA
FNKDALLNWLKSKNPGEKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFH
IDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCR
NGPLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKT
KVNWMMHSLAKDNRP
>A0A6P8S7F2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MPPAMTDSFDIWAVDSQISGDGPITVDCLLPTGIYIQLDVHRETTISHIKQLLWKEAQTY
PLFHLLMAIDSYMFECVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSKI
GVLIGKGLHEFDALEDPEVKEFRSKMRKISEEKIQSLLGLSWMDWLKRTFPPELEPSIPE
NFQDKLYGGNLVVAIHFDNCQDVFSFQVSPNMNPVKVNELAIRKRLTIRGREDEEINPYD
YVLQVSGKLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCNIKKMCEQEMNAIEAAIK
RKPTNLPLPLPPKTRTMSLMAQSVWNFCSPFKILLVRGSKVNAEENVKVQARAGLFHGTE
LLCKTVVSTEIPSGNDYIWNETLEFDITVCDLPRMARLCFAVYAVMDKMKTKKSTKTANT
KYPTIRKAGKVHYPVAWVNTMIFDFKGQLKTGDITLHCWSSFPDELEEMLNPMGTVRRNP
YPENATALYIKFQEYSKLAIYYPPFDKILEKAAEIARQSDSINMSGRGGKKFFIELKEIM
ERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWSKLP
PREALELLDFNYPDQYVREYAVNCLKQMSDEELSQYLLQLVQVLKYEPFLDCSLSRFLLE
RALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVSHMKVLTKQVVALNKLRTL
NNLIKLNAVKLSRAKGKETMQTCLKQSTYREALSDFQSPLNPSVILSEVNIEKCKYMDSK
MKPLWIVYSSKVFGGDPVGIIFKNGDDLRQDMLTLQLLRLMDMLWKESGLDLRIVPYGCL
ATGDRSGLIEVVSAAETIADIQLNSCNVAATAAFNKDALLNWLKEYNLGDDLDRAIEEFT
LSCAGYCVATYVLGIGDRHNDNIMVRKTGQLFHIDFGHILGNFKSKFKIKRERGPFILTY
DFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQ
YLKDSLALGKTEDEALKQFRQKFDEALRESWTTKVNWMAHTMRKDYRS
>Q6NTI2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Danio rerio|TrEMBL
MEQQASDDEPPVVRREENKRRRRRMKAFTSASAVSMEHIAVEFVLPTTNKNSKTLDTLQL
DVTGNWTVEQVKVQLWHRAVTSKLCPEFYQKYSPDYCILLYQKKGNWYEIYDKQQVFQTL
DCIRYWKALRKDVGKIHLVVRQQPAEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRK
LLTPRKIELSDRDPNLYSMDPWMTTTPMPEYLLSKISNNHILMVIHKETTSQTIKVSIDD
TPVQVLQSFFAKITNKRALLGISEDVSESDFVLRVCGREEYLYGNNAIKDFHWIRQCLKN
GEEIHLVLEHPPNPEQDVVQKEDWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNR
KFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTSSKPFTEEVIWNTWLEFNIK
IKDLPKGARLSLQVSCGKAQTQTSKETECKNKSRLLYYVNLLLVDHRSLLRQGEFILHMW
KMPEKSEDNSSVNADKLTSATNPDKNNSMAVAILLDKYCYPVALPKSKDSPDIEGERGQR
EMPNHLRKQFEQIIATDPLHPLTSEDKELLWHFRQECMRDPKAYPKFLSSVKWGKQEAVA
ITHHLLERSTIWDRSVLDVGLVLQLLDCHFSDENVRTIAVRKLETLGDDDVLRYLLQLVQ
AVKFEPYHDSALARFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCG
EEMLQDFRKQVEITEALQKVAREIKQISAEKYDISAQVVFQLRQKLEGLQVLGLPDSFKV
PYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDMLIL
QILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDE
ILSQWLREKCVNEDKHQQAVDRFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDF
GHILGNYKSFLGISKERVPFVLTPDFLYLMGTTGKKSSPNFLQFQNVCLKAYLALRHHTN
LLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQFN
WFLHLVLGIKQGVEKRSA
>A0A8B7IUC7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Apteryx mantelli mantelli|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKIGKIYVVQKQKPSEVVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDNSELDFVLRICGRDEYITGETPIKNFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKANLQSHESPNSDLKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESVKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>G3I9B2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cricetulus griseus|TrEMBL
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFILPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDHFLLLYQKKGQWYEIYDRYQVVQTLD
CLRYWKMMHKSPGQIHVVQRHAPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKITNNCILIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMNIPESQSERDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
DEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPTLSSKASAEMPGSESKGKAQLLYYVNLLLIDHRFLLRHGDY
VLHMWQISGKVEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGMAMLQDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSSLP
KSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFQCADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETECLDLCLLPYGCISTGDKIGMIQIVKDATTIAQIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKDVCVRAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEY
IRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A8C2E6W8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLNFPVACSETISTIKKMVWMNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMSDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRTFCEERAQVRQMLPWDKWMEYNFPCDLEPCSVVAQS
RKLCSGKKIFVNVKFEGSEETFVLQQDPHDLPMVLKQNALRKKSTVFRSAKQEKPEDYSL
QINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRLVVQAGLFHGSELLCKVVISNEVSVCSEPVWDQKLVFDISVSDLPRMSR
LCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFSMSTWPSVPDDKG
DLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKLWLAEHMKLREIVDNKNYTE
FFEDEKELLWKLREEVRQRYPESLPKLLLITKWNKHEDVAQMVSLLRKWPELPAIHALEL
LDYSFPDPHARSFTIRCLRKLSDDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKK
IGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSIFHIKSLIKQNEALNKMKALNDFVKSG
SQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLM
YKNKYDNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIE
VVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVAT
YVLGIGDRHSDNIMISETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGR
TNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGK
SEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A8D2FNP3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Theropithecus gelada|TrEMBL
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSSGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>F6W7C8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca mulatta|TrEMBL
MELENYEQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSMASDFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPAVSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDTCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A1S3MDU7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo salar|TrEMBL
MPPGEYGMLGEWKKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRPFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPMILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTIVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKQNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKV
VTSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKTKKPRSTKKKNKKADCP
LAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFPN
IRPHPLYYPHFDKLRDLEKNGGKVIATKVEHMKLKEIVDNKNYTEFFEDEKELLWKLRGV
VRERYPESLSKLLLITKWNKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTI
SCLRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLKSEMHV
SSVSLRFGLILEAYCRGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKL
CIKQEAYMEALSYLLSPLNPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIF
KNGDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQ
RNNSNSAATAAFNKDALLNWLKSKNPDRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHND
NIMIKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFR
ECCEQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKV
KFNEALRESWKTKVNWMMHSLAKDSRL
>A0A3Q7MU36|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinus ursinus|TrEMBL
MPPGLDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRGPTRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLYQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFRVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALSDFVKVSSQKTTKPQTKELMHLCMR
QETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDTQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A6P5PID9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mus caroli|TrEMBL
MPPGVDCPMEFWTKEESQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLRVCNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYA
LQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHFSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMKLIVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGHITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQLSQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAI
KSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHV
PSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHM
CMRQETYMEALSHLQSPLDPSTLLEEVCSVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGI
IFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIAN
IQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERF
RGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFR
VKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8B8WYK9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balaenoptera musculus|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYA
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPLKKPASVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCAKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A5N4DD28|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Camelus dromedarius|TrEMBL
GGLILPSLPLQDDWYLRSKSRMPPGVDCPMEFWTKEENQDVAVDFLLPTGVYLNFPVSRN
ANLSTIKKVLWHRAQYEPLFHMLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVL
RLVAREGDRVKKLINSQISLLIGKGLHEFDSLQDPEVNDFRAKMRQFCEEAAVRRQQLSW
EAWLQYSFPLQLEPSARSWGPGTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMAC
ALRKKATVFRQPLVEQPEDYTLRVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHS
SSILAMRDEQSNPASQVQKPRTKPPPIPMKKLASCLHPAQPSSVSLWSLEQPFCIELIQG
SKVNADERMKLVVQAGLFHGNETLCKTVSSSEVSVCSEPVWKQRLEFDINVCDLPRMARL
CFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGECRLYMWPSVPDEKG
ELLNPSGTVRSNPNTESAAALVIFLPEVAPHPVYYPALDKILELGRHGEHGRFTEEEQLQ
LREILERRGSGELYEHEKDLVWKMRHEIQEHFPEALARLLLVTKWNKHEDVAQMLYLLCS
WPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELT
KFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALS
KLKALNDFVKVSSQKTPKPQTKELMHMCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCT
FMDSKMKPLWVMYSNEEAGSDGSVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRM
TPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDR
AIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRENGQLFHIDFGHFLGNFKTKFGINRERV
PFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYSILRRHGLLFLHLFALMRAAGLPELS
CSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>P91634|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Drosophila melanogaster|TrEMBL
MNMMDNRALAYVAHQPKYETPPEEAEPPCMRFSVNLWKNEMLNWVDLICLLPNGFLLELR
VNPANTIQVIKVEMVNQAKQMPLGYVIKEACEYQVYGISTFNIEPYTDETKRLSEVQPYF
GILSLGERTDTTSFSSDYELTKMVNGMIGTTFDHNRTHGSPEIDDFRLYMTQTCDNIELE
RSAYTWQQRLLYEHPLRLANSTKMPELIRERHPTRTFLIVVKNENDQSTFTLSVNEQDTP
FSLTESTLQKMNRSQMKMNDRTSDYILKVSGRDEYLLGDYPLIQFLYIQEMLSDSAVPNV
VLQSVYRLESYINHHNEQAMVTKRPLPKKRTVHLHKSISSLWDMGNYFQLTLHSISNVNF
DKTRALKVGVHVCLYHGDKKLCAQRSTDSPNGNFDTFLFNDLVMDFDIQMRNLPRMTRLC
IVIFEVTKMSRSKKSSNNKDIALKDVPYNKNPLAWVNTTIFDHKDILRTGRHTLYTWTYA
DDIQSVEVFHPLGTIEPNPRKEECALVDLTFLSSGTGTVRYPSEEVVLQYAADREQVNRL
QRQLAGPEKPIKELKELMANYTGLDKIYEMVDQDRNAIWERRNDILRELPEELSILLHCV
YWKERDDVADMWYLLKQWPLISIERSLELLDYAYPDPAVRRFAIRCLHFLKDEDLLLYLL
QLVQAIKHESYLESDLVVFLLERALRNQRIGHYFFWHLRSEMQTPSMQTRFGLLLEVYLK
GCKHHVAPLRKQLHVLEKLKQGSLIAKKGSKEKVKTMLQDFLRDQRNSAVFQNIQNPLNP
SFRCSGVTPDRCKVMDSKMRPLWVVFENADVNASDVHIIFKNGDDLRQDMLTLQMLRVMD
QLWKRDGMDFRMNIYNCISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSW
LKEHNKPADKLNKAINEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILG
HFKEKLGVRRERVPFVLTHDFVYVINKGFNDRESKEFCHFQELCERAFLVLRKHGCLILS
LFSMMISTGLPELSSEKDLDYLRETLVLDYTEEKAREHFRAKFSEALANSWKTSLNWASH
NFSKNNKQ
>A0A8C9NEB0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Serinus canaria|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>V8P1B9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ophiophagus hannah|TrEMBL
MPPRPSSGELWGMHLMPPKILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVELRDANAPHSRALYVCPPNIESSDLPKHI
YNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLKL
CVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMTKESLYAQLPLDT
FAMPSYSRRISTATPYMNGEASAKSLWAINSHLRIKILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLQYEMLVFDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFS
SPVKFPDMSVIEEHANWIISREQGFNYNHAGLSNRIARDNELRDNDKEQLRAICTRDPLS
EITEQEKDFLWSHRHYCVSMPEILPKLLLSVKWNSRDEVAQMYCLIKDWPQIRPEQAMEL
LDCNYPDPMVRAFAIRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQ
RIGHFFFWHLKSEMHNKNVSQRFGLLLDSYCRACGMYLKHLSRQVEAMEKLINLTDILKQ
EKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLWL
NWENPDIMSELLFQNNEIIFKNGDVSCSFFRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQ
CKGGLKGALQFNSHTLHQWLKDKNKGEMYDPAIDLFTRSCAGYCVATFILGIGDRHNSNI
MVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQ
EMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMK
QMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C4XLJ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Falco tinnunculus|TrEMBL
MPPGIYCPTEFWAKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLHISTKNIFVNIKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVEKPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSAIIAMRDEQTNCIASPPKTT
PKPPPLPKKKPNYSSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQVGDTDAFLGRHRNSLALLKLQLKEILERRSHTELYEHEKDLVWKMRYDIR
DQYPQALAKLLIITKWNKHEDVAQVRMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKNNLTVLDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSE
MHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQKATKPQTKEM
MHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVG
IIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIA
NIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRH
SDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFER
FRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHF
RLKFNEALRESWKTKVNWLAHNVSKDNRQ
>H0V837|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cavia porcellus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRYVIFFFLLLFKEHCPLAWGNINLFDYTDTLVSGKMALN
LWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREA
GFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPLSEITEQEKDFLWSHRHYCVTIPEI
LPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLT
DDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRF
GLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDF
MDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNG
DDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKG
GLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVK
DDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMC
YKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMN
DAHHGGWTTKMDWIFHTIKQHALN
>A0A091JEF4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Egretta garzetta|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSSELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFIAYIRKTLALDKTEQEALEYFM
KQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A091IRR7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Egretta garzetta|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHIRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENIPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHACLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSGSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A671K7E6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MKAFTSTSAVLTDQIAVEFVLPTTNKNSKNPDTLHLDVTGNWTIEQVKVQIWHRAVTTKL
CPEFYQKYSPDHCMLLYQKKGNWNEIYDKQQVFQTLDCIRYWKALRKEVGKIHLVVRQQP
TEDSLQYQRFLNHLIGYDVTDVSNVHDDELEFTRRKLLTPRKIELSDRDPKLYSMDPWIT
TKPLPEYLLSKISNNHILVVIHKDTTSQTIKVSIDDTPVQVLQSFFTKITKKRAILGISE
DVSESDFVLRVCGREEYLYGNYAIKDFHWIRQCLKNGEEIHLVLERPPDPEQDVVQKEEW
SQVDDCTGVAGTHEQLTITEKDHEKVFTISLWDCNRKFRVKILGIDIPVLPRNSELIVFV
EASIFHGQQLLAQERTTSKPFTEEVLWNTWLEFNIKIKDLPKGARLSLQVSCGKAQTQTS
KENECKNKSRLLYYVNLLMVDHRSLLRQGEFILHMWKMPEKSEDNSSVNADKLTSATNPD
KNSSMAVAILLDKYCYPVALPKSKDSPDSEMEGERGQREMPNHLRKQFEQIIATDPLHPL
SSEDKELLWHFRQECMKDPKAYPKFLSSVKWGKQEAVAITHCLLERSTIWDRSSLDVGLA
LQLLDCHFSDENVRTMAVRKLETLEDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALG
SMRIGHFLFWFLRSEIAQSMHYQQRYAVILEAYLRGCGEAMLQDFRKQVEMTEALQKVTR
EIKQMSIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLRQDMLILQILLIM
ESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNTGAFKDEILSQWL
REKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGNLFHIDFGHILGN
YKSFLGISKERVPFVLTPDFLYVMCTTDKKSSPNFLQFQNVCLKAYLALRHHTNLLIILF
SMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKGWTVQFNWFLHLV
LGIKQGVEKRSA
>A0A7J8DCU9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Molossus molossus|TrEMBL
MCFNFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISSIKKMLW
TQIHNYPMFNLLMEIDSYRFACVNQTAVYEELEDETRRLCDVRPFLPVLKVVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWIDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDE
VSPYDYVLQISGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAISRNSSNLPLPLPPKKRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGT
ELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTIN
ASKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQT
NPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEI
LDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKL
PPREALELLDFNYPDQYVREYAVGCLRQMSKRIQSRIGKGKRFMGQSLEETSDEELSQYL
LQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVHIPAISIQFGVILEAYC
RGSVGHMKVLSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQ
SPLNPCVILSELYIEKCKYMDSKMKPLWLVYNNQVFGEDSVGVIFKNGDDLRQDMLTLQM
LRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKD
ALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFG
HILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNL
FITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNW
MAHTVRKDYRS
>A0A671L7P8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLFLPFWLCSKWHKTFSTGHHEFDSQKNHEVNE
FRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQSGKSHSGKKILVNVKFEGS
EETFVLQQDPQDLPMFLKRNALRKKSTVFRPAKQEKPEDYTLQVNGRWEFIYGKYPLCQF
KYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRTRAQSKPPPLPLKRLVVQAGL
FHGSELLCKVVTSNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTK
KKNKRADCPLAWVNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDST
AGLLIRFPNIRPHPLYYPPIEKLNELGMNCEKVVATKEEHLKLREIVDNKNYTEFFEDEK
ELLWKLRKEVRQRYPESLPKLLLITKWNKHEDVAQMVCLLRKWQELPAIHALELLDYSFP
DPHVRSFTIRCLRNLRNDELFQYLLQLVQVLKYESYLDCDLTCFLLERALSNKKIGHFLF
WHLRSEMHVPSVSLRFGLILEAYCRGSIFLIKSLMKQNEALNKMKALNDFVKSGSQKATR
IQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKDKYD
HVGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSD
TIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIG
DRHSDNIMIRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEK
FERFRECCEQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEAL
KNFKVKFNEALRESWKTKVNWMMHSFAKDNR
>A0A671K6E5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
ILLRGIEMKIDDEPPVVRREENKRRRRKMKAFTSTSAVLTDQIAVEFVLPTTNKNSKNPD
TLHLDVTGNWTIEQVKVQIWHRAVTTKLCPEFYQKYSPDHCMLLYQKKGNWNEIYDKQQV
FQTLDCIRYWKALRKEVGKIHLVVRQQPTEDSLQYQRFLNHLIGYDVTDVSNVHDDELEF
TRRKLLTPRKIELSDRDPKLYSMDPWITTKPLPEYLLSKISNNHILVVIHKDTTSQTIKV
SIDDTPVQVLQSFFTKITKKRAILGISEDVSESDFVLRVCGREEYLYGNYAIKDFHWIRQ
CLKNGEEIHLVLERPPDPEQDVVQKEEWSQVDDCTGVAGTHEQLTITEKDHEKVFTISLW
DCNRKFRVKILGIDIPVLPRNSELIVFVEASIFHGQQLLAQERTTSKPFTEEVLWNTWLE
FNIKIKDLPKGARLSLQVSCGKAQTQTSKENECKNKSRLLYYVNLLMVDHRSLLRQGEFI
LHMWKMPEKSEDNSSVNADKLTSATNPDKNSSMAVAILLDKYCYPVALPKSKDSPDSEME
GERGQREMPNHLRKQFEQIIATDPLHPLSSEDKELLWHFRQECMKDPKAYPKFLSSVKWG
KQEAVAITHCLLERSTIWDRSSLDVGLALQLLDCHFSDENVRTMAVRKLETLEDDDVLRY
LLQLVQAVKFEPYHDSALARFLLKRALGSMRIGHFLFWFLRSEIAQSMHYQQRYAVILEA
YLRGCGEAMLQDFRKQVEMTEALQKVTREIKQMSAEKYDVSAQVVFQLRQKLEGLQTSGL
PDNFKVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSSDTIGIIFKDGDDLR
QDMLILQILLIMESIWELESLDLSLLPYGCISTGNKIGMIEIVKDATTIANIQQSTVGNT
GAFKDEILSQWLREKCVNEDKHQQAVERFVFSCGGYCVATYVLGIGDRHNDNIMITETGN
LFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMCTTDKKSSPNFLQFQNVCLKAYLA
LRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAKQHFLDQIEICRDKG
WTVQFNWFLHLVLGIKQGVEKRSA
>A0A671S347|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDATGSHSRALYVYPPNVESSSELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHAMTEADIEQLRQLGNRDPL
SEITEQEKDFLWRHRQYCVNIPEVLPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKISSF
CSLFCQGFTYTDLNIMIIRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYM
DALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGD
DLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGG
LKGALQFNSSTLHQWLKDKNKGEMYDMAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKD
DGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERCIYLG
WTR
>A0A671L1H5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus anshuiensis|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLFLPFWLCSKWHKTFSTGHHEFDSQKNHEVNE
FRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQSGKSHSGKKILVNVKFEGS
EETFVLQQDPQDLPMFLKRNALRKKSTVFRPAKQEKPEDYTLQVNGRWEFIYGKYPLCQF
KYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRTRAQSKPPPLPLKRQNTSSLW
SIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSNEVSVCSEPVWDQKLVF
DIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAWVNTMVFDYKDQLKTGEFS
LSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKLNELGMNC
EKVVATKEEHLKLREIVDNKNYTEFFEDEKELLWKLRKEVRQRYPESLPKLLLITKWNKH
EDVAQMVCLLRKWQELPAIHALELLDYSFPDPHVRSFTIRCLRNLRNDELFQYLLQLVQV
LKYESYLDCDLTCFLLERALSNKKIGHFLFWHLRSEMHVPSVSLRFGLILEAYCRGSIFL
IKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPS
IVLCELCADKCKFMDSKMKPLWLMYKDKYDHVGIIFKNGDDLRQDMLTLQMIQLMDVLWK
TEGLDLRDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGN
FKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLF
ALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSF
AKDNR
>A0A7L3T8K8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rissa tridactyla|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLTWAAWMEYNFPLQLEPMAKGLGT
GPLHTPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQPFYVELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFRYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKTTKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2I4KAQ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tachysurus fulvidraco|TrEMBL
MPPGVFCDLQDVWEKEGREQVTMEFLLPTGIYLSFPVACSDTIATIKKILWKNARSEPLF
SILSSPDAYVFTCINRTAEREDLEDEQRRLCEVRPFLPVFRLVAREGDRVEKLINTQISL
LLGKGLHEFDTQKNHEVNEFRAKMRSFCEEKAQDRHLLPWHQWMEYNFPCDLEPFSPVAQ
CGKAHTSTKKIFINVKFEASEESFMLQLDPQDLPLVLMKSALRKKATVFRPVKQDKLEDY
TLQVTGRWEFIYGKYPLCRFKYIFSCLYGGQTPHLTMVHHSTILKYQEEQGGLSNHMSKS
RSQSKPPPLPLKKQNTLSLWSIHEPFFIHLLHGTRVNADESMKLVVQAGLFHGSELLCKV
VTSSEVTVCSDPVWDQKLSFDIHLCDLPRMTRLCLALYGVLDKPRKQRSTKKKNKKADCP
LAWVNTMLFDYKDQLKTGEIFLSTWPSAPDDKGGLLNPMGTVEKNPNMDSSAGLLIHFPS
FKPHPLYFPPLEKLHEVNGEKAVVTKEEHLKLKEIVDNKNHTDFFEDEKELLWKLRGEVR
ANYPESLSKLLLITKWNKREDVAQIVALLQKWPDLPALHALELLDYTFPDPHVRSFTIRC
LRKLRDDELFQYLLQLVQVLKYEPYLDCDLTTFLLERALSNKRIGHFLFWHLKSELHVPS
ASLKFGLILEAYCRGSIYHMKTLMKQNEALSKMKALNDFVKSAFQKSASRLQITEDMKLC
IKQDTYLEALSGVLSPLNPSIILSEICTDRCKFMDSKMKPLWLMYKNKCVQSDTSGIIFK
NGDDLRQDMLTLQMIQLMDILWKSEGLDLRMIPYGCLSTGDKTGLIEVVKNSDTIANIQR
NKSNSAATAAFNKDALLDWLKSKNPGDKLEQAIEEFTLSCADYCVATYVLGIGDRHSDYI
MIRENGQLFHIDFGHFLGNFKAKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREC
CEQAYKILCRNGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALCKTEEEALKNFKVKF
NEALRESWKTKVNWMMHTFAKDNR
>A0A3L7IHA9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chinese hamster|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
SFTMPSYSRRISTATPYMNGETTTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPL
HYCVTIPEILPKLLLSVKWNSRDEVAQPEQAMELLDCNYPDPMVRSFAVRCLEKYLTDDK
LSQYLIQLVQVLKYEQYLDNLLSYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDET
QKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPD
IMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRNSHTIMQIQCKGGLK
GALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDG
QLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQEYTKTREFERFQEMCYKA
YLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFTKQMNDAH
HGGWTTKMDWIFHTIKQHALN
>A0A3L7IHA9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cricetulus griseus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFV
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
SFTMPSYSRRISTATPYMNGETTTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPL
HYCVTIPEILPKLLLSVKWNSRDEVAQPEQAMELLDCNYPDPMVRSFAVRCLEKYLTDDK
LSQYLIQLVQVLKYEQYLDNLLSYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDET
QKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPD
IMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRNSHTIMQIQCKGGLK
GALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDG
QLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQEYTKTREFERFQEMCYKA
YLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFTKQMNDAH
HGGWTTKMDWIFHTIKQHALN
>A0A7L4EF68|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hirundo rustica|TrEMBL
MPPGIYCPMEFWSKGENQNIHVDFLLPTGIYLNLSVPCNASLGAIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPVAKGFGS
GSLQIPTKNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
WEVAVCSEPVWRQRLDFDINICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIVLAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C2LJ86|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cricetulus griseus|TrEMBL
LPPGSANPVTLHREQRQEVYWHVASPQGVNFCLGGLPVFGAHCDPLSQVLWHRAQYEPLF
HMLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISL
LIGKGLHEFDSLRDPEVDDFRTKMRQFCEEVAAHRQQLGWEDWLQYSFPLQLEPSARSWR
AGILRVTNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEDY
ALQVNGRHEYLYGNYPLCQFQYICSCLHSGLTPHLTMVHASSILAMRDEQSNPAPPVQKP
RTKPPPIPAKKPSSVSLWSLEQPFCIELMEGSKVNADERMKLVVQAGLFHGNEMLCKTVS
SSEVNVCSEPVWRQRLEFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSRKADCPIA
WANLMLFDYKDQLKTGERRLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLPEVA
PHPVYFPALEKILELGRHGEQRGRITEEEQLQLREILERRGSGELYEHEKDLVWKMRHEV
QEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIK
SLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRYSEMHV
PSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHM
CMRQETYMEALSHLQSPLDPSTLLEEVCACRPPSLQCTFMDSKMKPLWIMYSSEEAGSAG
SVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSD
TIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIG
DRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEK
FERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEAL
KQFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A672TFY0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYILDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A3B4ZZX4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Stegastes partitus|TrEMBL
MPPGKYGMQEEWEKEEDQQITMDFLLPTGIFLRFPVSRNDTIKNIKKMVWKNARSEAMYS
GLGDPDGYVFTCIKQTAESEELEEESRRLSDVRPFMFVLRLVAREGDRVEKLTNTQISQL
IGKGLHEFEAQKNHEVDEFRTKMRAFCEEKAQERESLPWQQWMEYSFPCELEPCCSPPDS
WSMKSKKSKKIFVQIKFEASQESFMLQQDPHDLPVALMKSALKKKATVFRSLRQEPEDYT
LQVNGRWEFIYGKHPLCQFKYIFSCLRNGQNPHLTMTHYSTIAKYKEEQTKVCSQASKSR
SLSRPPPLPLKKLVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQKLEFDINVADLPRMS
RLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDD
KSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPLDKISDIEKNGDAVYVTKDEY
VRLKEIMDNKNYTEFFEDEKELLWKLRTDVRDRYPESLSKLLLITKWNKREDVVQMVSLL
RHWPDLPAISALELLDYSFPDPAVRSFTIRCLKKLSDDELLQYLLQLVQVLKYESYMDCD
LTTFLLERALSNRRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGDIHHIKLLTKQNEA
LGKMKALSDIVKSGSQKMTVEDLKLCIRQESYLDALSDLYSPLNPSILLPEICAEKCRFM
DSKMKPLWLMYVNPAIQGDMIGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRDKLE
QAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRER
VPFILTYDFVHVIQEGKTNNSEKFERFREYCEQAYKILCRNGTLFVNLFAMMKAAGLPEL
TSFKDIQYLKDCLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSMAKDNRP
>A0A672U483|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVHDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAVN
RKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTELLC
KTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTNPYT
ENATALHIRFQEYAKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVEYLKNKGKKYYNGQIDEELSQYLLQLVQVLKYEPFLDCAL
SRFLLERALANRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEAL
NKMKTLNSLIKLNAMKQSKAKGKDAMQTCLKQNAYREALSDLQSPLNPSVILSELHVEKC
RYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRI
LPYGCLATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGFLFHI
DFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKH
GNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTK
VNWMAHTVRKDYRS
>A0A672U2Q8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strigops habroptila|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISQIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVHDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVVPE
SFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEVDPAD
YVLQVSGRLEYVFGDHPLIQFQVCKALWNLPQQFSGPLSVWDISNPFKIILLKGNKLNTE
ENAKVHVRAGLFHGTELLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYA
VMDKMKTKKSTKHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYAKQPINYPPFDKVRYDGRGGKKFYVVLKEIMERDPLSQLCENEM
DLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPREALELLDFNYP
DQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALANRRIGQMLF
WHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNSLIKLNAMKQSK
AKGKDAMQTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMKPLWIVYNNKMF
GGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLATGDHSGLIEAVS
SSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLSCAGYCVATYVL
GIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGN
TEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEE
EALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3P8VZT4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cynoglossus semilaevis|TrEMBL
MPPAMTDLLDIWVAHSPMLGHTPDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
TLPLFTALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRNKIVRLSEERMQRVCLMTCTEWLQACFSPQLDPG
STTAVTDEVSEQSDLKVIIHFEQSQDSTILKVPSSCTTTELMDLAIKKWLTTHSPEEEAS
RSEYVLRLSQCLEFLCGNHPLSQYKYIRTCMQAKESPSLTMVHMSTIKAMFDKEIKTIGA
VVNHKSLNPLPLPLPPKRRAPTQVQMCVWDLTSTFRIVLVSANKVNADETAKVQVRAGLF
HGTELLCKPVVSSESSQRSDHTWRESTLEFEISVCDLPRMTRLCFAIYAVMDKVKKQKST
KNPHLYKYQTIRKAGKVHFPIAWVNTMVFDYKGHLKTGDINLHCWSSFPDELEEMLNPIG
TVQTNPYTENATALCIHFPEYSSHPVVFPPFDKILEKAAEIVGASDCSPMGRGGKKFYIE
LKEIMERDPLSQLCENEKDLIWTLRCDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPKLSPRDALELLDFNYPDQYVREYAVGCLHDMSDDELSQYLLQLVQVLRYEPYYDCALT
HFLLRRAHGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSVPHIEVLKKQVDALS
KLKSVNELIKHGNTKNARSKTKEAMLTKEAMMACLKQSGYSETLSDLCSPLNPSVMLSGI
NVEKCRYMDSKMKPLWIVYNNKLLMGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKESK
LDFRIVPYGCLATGDKAGLIEVVSSADTIANIQLTSSNMAAAAAFNKDALLNWLKERNSG
DALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGNTEKFGCFRRYCEEAYLILRNHGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>G1NC03|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Meleagris gallopavo|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8I3WPH5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callithrix jacchus|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSAAASLSPMELIPIEFVLPTSQRNCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRAPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKYLMDIPESQSERDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKVPAESPSSESKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCYPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVIAQLKQKLENLQNSHLP
KSFRVPYDPGLKAGALAILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIA
KIQQSTVGNTGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHN
DNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKF
QDICVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFL
DQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A5F4W5E9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callithrix jacchus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEETP
CLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQL
RAICTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWP
PIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVR
FLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEK
LINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRI
MSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDL
RMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYD
AAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRER
VPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMP
ELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C4BD42|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPGVFGMQDVWEKDGQQVTVEFLLPTGIYLTLEVSCSDTIGTIKKMLWRAARGEPLFGA
LSDPDAYVFTCINLTAEREDLEDEQRRLCDVRPFLPILRLVAREGDRVEKLINTQISHLI
GKGLHEFDSQKNHEVSEFRTKMRAFCEERAQERQRLPWYEWMESSFPCDLEPCSGLLKSS
KFHNFKKVFVNVKFEGSEESFMLQLDPQDLPVMLMKNALKKKATVFRPVRQEKPEDYTLQ
VLGRWEFIYGKHPLCQFKYIWCCMHEAQTPYLTMVHHSTITKYQEEQSCLTNQVTKTRSS
SKPPPLPLKKQNTTSLWTIQEPFYVQLVQGSRVNADEGMKLVVQAGLFHGSELLCKVVTS
NEVNVSSEPLWDQKLVFDISVGDLPRMTRLCLALYAVVGTTKKARSTKKKNKRADCPLAW
VNTMVFDYKDQLKTGDFSLSAWPSVPDEKSDLLNPMGTVEKNPNIDSAAGLLIRFPNIRP
HPLCYPPLDKAGLKTHIYMHMNCNITLLKEIVDNKNQTEIFEDEKELLWKLRVEMRDHYP
ESLSKLLLIGKWNKHEDVAQMVWLLRKWPDLPVLHALELLDYRFPDPYVRSFTIKCLRKL
RDDELFRYLLQLVQVLKYESYLDCDLTTFLLERALSNKNIGHFLFWHLRSEMHVSSASLR
FGLILEAYCRGNLYHIKSFMKQNEALNKMKALNDFVKSGSQKATRSQTIEDMKVCIRQEA
YMEALSDMLSPLSPSIILSEICTEKCKFMDSKMKPLWLMYKSKVAQADTVGIIFKNGDDL
RQDMLTLQMLELMDVLWKREGLDLRFLEEAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCE
QAYKILCRNGTLFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKIFKVKFNE
ALRESWKTKVNWMMHSVAKDNR
>A0A8C0FLE1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHAY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
SFQDKLYSGNLVVAVHFDNCQVGMIDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEEV
DPADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIE
AAINRKSSNLPLPLPPKKTRTTTNSVGSLARLKFLISLLQVHVRAGLFHGTELLCKTIVS
TEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKHYPVAWVNTMVF
DYKGQLRNGELVLHSWSSFPDELEEMLNPMGTVQTNPYTENATALHIRFQEYSKHVDLWV
TGMTRGSGKKFHIVLKEIMERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWN
KLEDVAQLQALLQIWPKLLPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLV
QVLKYEPFLDCALSRFLLERALANRRIGQMLFWHLRSEVHIPAVSIQFGLILEAYCRGSV
AHMKVLAKQVEALNKMKTLNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLN
PSVILSELHVEKCRYMDSKMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLM
DILWKEAGLDLRILPYGCLATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLN
WLKEYNLGDDLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILG
NFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITL
FALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHT
VRKDYRS
>A0A093HBH5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Struthio camelus australis|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNVWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDLKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLRRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSASAEKYDVTSQVIMQLRQKLERLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADATALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C4FXL9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Denticeps clupeoides|TrEMBL
MPPTMMDVLDLWAELGEVEHVSVDFLLPTGLYIQMEVPREATIQHIKQLLWKEAAGYPLF
TLLGAMEGHMFECVNQTAVHEELEDETRRLCDVRPFLPVLRVVTRSGGHNERLLDSKIGV
LIGKGLHELDSLQDQEIKDFRTKMQQISKEKIQRIQVMSWEEWLRTHFSPQLEVGQVDGM
IEKLCEDGIKVTMHYDQSQDTVSVRVDVSCTVRTLLELALRKWANTHGHNNSSCLSDYIL
RISSKLEILFEEHPLIQYKYIRECLLAQESPHLTVMHSSVLRGMFERELGCIASVCGHKQ
SNAPLPLPPKKRPPSMHTCVWDVQSQFKITLVRGIKVNTEESAKVYVRAGLFHGAELLGK
PAVSSDSSGRLEHLWNTTLEFDVAVSDLPRMSRLCFAIYAVMDKVKKQPKSIKTPHSKYQ
TIRKAGKVHYPIAWVNTMVFDYKGLLKTGDVVLYCWSSFPDELEEMLNPIGTVQTNPYTE
NATAIHITFPEYSQISVIFPPFDKILEKAAEMARGSDCPPMGRGGKKFHIELKEIMDREP
LSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWNKHEDMAQLQALLQIWPTLSHRDA
LELLDFNYPDQYVREYAVNCLRDMRYIHTHIYICTLHEIFDEELSQYLLQLVQVLRYEPY
YDCALSRFLLERSQLNRNIGHFLFWHLRSEMHMPAVSVQFALILEAYCRSSIPHIEVLKK
QVEALNKLKAVNALVKTGAVKSKARTKDSHLKEAMLTCLRQSGFTETLSDIHSPLNPSVL
LAEVKCKYMDSKMKPLWIVYNNKLLGGETLGIIFKNGDDLRQDMLTLQILKLMDLLWKEA
NLDLRIVPYGCLATGDHSGLIEVVSSADTIANILKTSSNMAATAAFNKDALLNWLKEKNS
GDTLERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFG
IKRERVPFILTHDFIHVIQQGKTANTEKFGSFRQYCEEAYLVLRRNGNLIITLFALMLTA
GLPELTSVKDIQYLKDSLALGKSEEEALKQFRQKFDEALRESWTTKVNWMAHHIAHAS
>A0A8C0FPL4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bubo bubo|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
VYAVLLALQESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYTLQVNGKCEYLY
GNYPLYQFQVSLVSHILFRGADALSRSSSKHVSSANRSSPCGFMVFPYFSFPQLVVQAGL
FHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARST
KKKSKKAVSEATAFFALQDCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPM
GTVQCNPNTESAAALVICFPSVASHPVYYPSFEQHITYTWAVRGQKLQLKEILERRSHTE
LYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALEL
LDFSFPDQYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRK
IGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKSS
SQKAPKPQTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIV
FNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTG
LIEVVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYC
VATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQ
QGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLA
LGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P7EM49|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ovis aries|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRIPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVCSQKTPK
PQAKELMHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEA
GSDGTVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVV
LHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYV
LGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTN
NSEKFERFRGYCETAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTE
EEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6P3EBV3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ovis aries|TrEMBL
MELENHEQPVVLREDNCRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGXGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>H0WUI6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Otolemur garnettii|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWSEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCLTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A851QFT1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tychaedon coryphoeus|TrEMBL
MELRDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTADFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDSPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GDYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYELLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIERCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILSQWLKERCMIEEKFQEAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFQKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6J0U6C8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pogona vitticeps|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCLPNGMIVTLECLREATLLSIKQDLFKEARKYPLFH
LLQEESSYIFVGVTQEAEREEFFDESRRLCDLRLFQPILKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDPEVQEFRRNILLVCREAVEARGSAGHQSQALYVYPPNVESSPELPKH
IYSKLDKGRIIVTIWVIVSPNNDKQKYTLKTPHDALPEQVIAEAIRKKTRSMHLSPEQLR
LCVQEYQGKYLLKVCGCDEYLLEKYPLSQYKYMRNCITIGRLPHLMLMSKETLYKQLPAN
VFVLPSYARRSATSSHVNGDVPTKSLWSLNSLLRIKILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDIVNTQRVPCSNPRWNEWLSYDIYLTDLPRAARLCVSICSVKGRKGAKEEHCP
LAWGNVNLFDYKDTLVAGKMALNLWPVPHGLEDLLNPIGVGGSNPNKETPCLELEFTWYS
HTVKFADAAEIEEHANWAMSREFGLNYCMVGLSNRLARDSSLDESELEQLQNICNRDPLS
EITEQEKDFLWRHRHYCVNIPETLPKLLLSVKWNSRDEVAQMYCLLREWPLIKPELSMEL
LDCNFPDPVVREFALKCLVKGLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLTMKALTNQ
RIGHFYFWHLKSEMHSKPVSQRFGLMLEAFCRGCGMYLKHLNRQVEAMEKLINLTDILKQ
EKKDETQKMQMKFLVEQMRRPDYMEALQGFICPLNPVHQLGNLRLDECRIMSSAKRPLWL
NWENPDIMSELLFTNHEIIFKNGDDLRQDMLTLQIIRIMESMWQNQGLDLRMLPYGCLSI
GDCVGLIEVVKSSHTIMQIQCKGGLKGALQFNSNALHHWLKDKNKGEGYDAAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGIQECTKTKEFERFQEMCYKAYLAIRQHANLLINLFSMMLGSGMPELQSFDDVAY
LRKTLALDKSEQEALEYFTKQMNEAHHGGWTTKMDWIFHTIRHMPLSEASHD
>A0A8B9F1A2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Amazona collaria|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYILDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C5EPM0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gouania willdenowi|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLTRLPNLMLMEKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEASTKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVTNKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCAVKYPDMTAVEDHANRTISREMGFTYNLSGQSNRVARDHALTDGDTEQLRQLSNRDPL
SEITEQEKDFLWRQRHYCMNFPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLADDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRFDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSPECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8D3E8M4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPGKYGMQEEWEKEGVQEIMMDFLLPTGILLKFPVSRNDTIKSIKKMVWKNARSEALFC
GLGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRAEKLINTQISLL
IGKGLHEFEAQKNHEVNEFRTKMCIFCEEKAQERQMLPWQQWMEYNFPCDLEPCCTPPHS
GSLKSKNTKKFFINVKFEACDVSRSQDPQDHPVALMRSALKKKANVFRSVRQEPEDYTLQ
VNGRWEYIYGKHPMCQFKYIFSCLRNGQNPHLTMVHHSTISKFQEEQGQMCSQEYKSRSL
SRPPPLPLKKVRGQRTLVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQRLEFDINVADL
PRMSRLCFALYAVIEKTKKPRGTKKKNKKAPFYLTWVNTMVFDYKDQLKTGEFLLSTWPS
VPDDKSELLNPMGTVEKNPNVDSAAGLLIRFANIRPHPLYYPPLDKVLVPKRLCWYMKLK
EIMDNKNYTEFFEDEKELLWHLRTEVRDRYPENLSKLLLITKWNKREDVVQMVNLLRNWP
DLPAIHALELLDYSFPDPAIRSFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTF
LLERALSNRRIGHFLFWHLRSEIHVASVTLRFGLILEAYCRGNIHHIKLLTKQNEALSKM
KTLSDFVKSGSQKLTAEDLKLCIRQESYLEALSDLLSPLNPSIILTEICADKCRFMDSKM
KPLWLMYKNNWAPEDMVGIIFKKGDDLRQDMLTLQMIQLMETLWKREGLDLRMIPYGCLS
TGNKMGLIEVVENSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTL
SCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYD
FVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTSFKDIQY
LKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A8D3BM23|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPGKYGMQEEWEKEGVQEIMMDFLLPTGILLKFPVSRNDTIKSIKKVRQSEALFCGLGD
PDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRAEKLINTQISLLIGKG
LHEFEAQKNHEVNEFRTKMCIFCEEKAQERQMLPWQQWMEYNFPCDLEPCCTPPHSGSLK
SKNTKKFFINVKFEACDESFMLQQDPQDHPVALMRSALKKKANVFRSVRQEPEDYTLQVN
GRWEYIYGKHPMCQFKYIFSCLRNGQNPHLTMVHHSTISKFQEEQGQMCSQEYKSRSLSR
PPPLPLKKLNTSSLWSITEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSSE
VTVCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPIAWVN
TMVFDYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFANIRPHP
LYYPPLDKINDIERNGDAASVTKEEMVNLLRNWPDLPAIHALELLDYSFPDPAIRSFTIR
CLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVA
SVTLRFGLILEAYCRGNIHHIKLLTKQNEALSKMKTLSDFVKSGSQKLTAEDLKLCIRQE
SYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNNWAPEDMVGIIFKKGDD
LRQDMLTLQMIQLMETLWKREGLDLRMIPYGCLSTGNKMGLIEVVENSDTIANIQRNNSN
TSLTQRLDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGN
FKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLF
AMMKAAGLPEYSAIVYICLWYCK
>A0A8D3EFU2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Scophthalmus maximus|TrEMBL
MPPGKYGMQEEWEKEGVQEIMMDFLLPTGILLKFPVSRNDTIKSIKKMVWKNARSEALFC
GLGDPDAYVFTCINQTAEREELEEESRRINDVRPFMCVLRLVAREGDRAEKLINTQISLL
IGKGLHEFEAQKNHEVNEFRTKMCIFCEEKAQERQMLPWQQWMEYNFPCDLEPCCTPPHS
GSLKSKNTKKFFINVKFEACDESFMLQQDPQDHPVALMRSALKKKANVFRSVRQEPEDYT
LQVNGRWEYIYGKHPMCQFKYIFSCLRNGQNPHLTMVHHSTISKFQEEQGQMCSQEYKSR
SLSRPPPLPLKKLNTSSLWSITEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVV
TSSEVTVCSEPLWDQRLEFDINVADLPRMSRLCFALYAVIEKTKKPRGTKKKNKKADCPI
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKSELLNPMGTVEKNPNVDSAAGLLIRFANI
RPHPLYYPPLDKVLVPKRLCWVHTEILICNSVSEKNRLSTAHILQLSHYEKELLWHLRTE
VRDRYPENLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAIRSFTI
RCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHV
ASVTLRFGLILEAYCRGNIHHIKLLTKQNEALSKMKTLSDFVKSGSQKLTAEDLKLCIRQ
ESYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMYKNNWAPEDMVGIIFKKGD
DLRQDMLTLQMIQLMETLWKREGLDLRMIPYGCLSTGNKMGLIEVVENSDTIANIQRNNS
NTSLTQRLDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLG
NFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNL
FAMMKAAGLPELTSFKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHS
LAKDNRP
>A0A8B6BF31|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mytilus galloprovincialis|TrEMBL
ALKFEPYLDSPITRFLLKRALQNQKTGQLFFWHLKSEIHNTSIQLRFGLVLEAFCRGCGS
NLKMLLRQVEALDKLTKLTNMIKNEVKDDINEIMKFLANQLQQPDYQDGLKNFLSPLDNS
HILGDLDISHCSVMTSKKKPLWLVFSNPDVMADIWFTDYKLIFKNGDDLRQDMLTVQLFK
IMDTLWKNEGLDLRLIPYSVKNGIRAAVQMDSLGLYNWIMYHNKDREEQAISNFTRSCAG
YCVATFILGIKDRHSGNIMVRKNGQVFHIDFGHFLDHRKKKFGITRERVPFVLTMDFIRV
IARGSDQPLKHKEFKKFQQLCCEAYLIIRKNAYLFINLMTMMLSCGIPELQSLDDISYLR
KTLAVEEKDDEKALKYFIAKFNSAYSDAWTVKTDWLFHYMKNR
>A0A1A8KRZ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nothobranchius kuhntae|TrEMBL
GIFLKFPVPRNDTIKNIKKMVWRNAKSEALYCGLGDPEGYVFTCINDTAEREELEEESRR
ISDVRPFMCVLRLVAREGDRGEKLTNSHISSLIGKGLHEFEAQKNHEVDEFRSKMRTFCE
EKALERHNLPWQQWMEYSFPCDLEPCCSPPVHGGTKSKHTKKLFINVKFEACDESFMLQQ
DPLDIPVALMKSALKKRATVFRSVRQEPEDYTLQVSGRWEFIYGNHPLGQFKYIFSCLRN
GQNPQLIMVHHSTISKYQEEQGQLCSQAVGKIRSQSRPPPLPMKKQNTSSLWSINEPFYI
HLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQKLDFDINVSDLP
RMSRLCFALYAVIEKTKKPRGTKKKNKRADCPIAWVNTMVFDYKDQLKTGEFILSTWPSV
PDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPLDKMIVMERNGDAVFATK
VERMRLKEIMDNKNSTEFFEDEKELLWKLRTEVRDCYPESLSKLLLITKWSKREDVVQMV
SLLRNWPDLPAIQALELLDYSFPDPAVRSFTIRCLRKLSDNELLQYLIQLVQVLKYESYL
DCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIKLLTKQ
NEALGKMKALSDIVKSGCQKMTVEDLKLCIRQESYMEALSNLMSPLNPSIILVELCADKC
RFMDSKMKPLWMMYKNPSEHADMVGIIFKNGDDLRQDMLTLQMIHLMEDLWKKEGLDLRM
IPYGCLSTGNKMGLIEVVKHSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKLDQ
AIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERV
PFILTYDFVHVIQQGRTNNSEKFERFREYCEWAYKILCKNGTLFVNLFAMMKAAGLPELT
SSKDIQYLKDSLALGKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A673MUJ5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPGVYGMQDVWEREGWQQINIEFLLPTGIYLNFPVARSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFMPILRLVAREGDRVEKLITTQISLL
IGKGHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWEPWMEFNFPCDLEPCSVVAQS
GKSHSGKKILVNVKFEGSEETFVLQQDPQDLPMFLKWNALRKKSTVFRSAKREKPEDYTL
QVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRTRA
QSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSCLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGMNGEKVVATKEEMVGLLRKWPELPAIHALELLDYSFPDPHVRSFT
IRCLRILRNDELFQYLLQLVQVLKYESYLDCDLTCFLLERALANKKIGHFLFWHLRSEMH
VPSVSLRFGLILEAYCRGSIFLIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMK
VCIKQDTYMEALSDVVSPLNPSIVLCELCADKCKFMDSKMKPLWLMYKDKYDHVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRN
NSNSAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECC
EQAYKILCRNGTLFVNLFALMKAAGLPELSSSKDIQTLWHWGNLRRKH
>A0A673IL22|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSAELPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKITHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYMLKVCGCDEYLLEKHPLSQYKYIRSCITLGRLPHLMLVSKDSLYSQLPSS
GFMAPSYSRRTPQPSPCPGGGDPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDEQQIEEHANWKYDLVRCSRLVCDSSISQADAEQLRTLCSRDPLYELSEQE
KDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVHNLDIFLRWKNAVLQMLETWLSKERLL
SNSTPRFLTDDEELTEQPSSLRQCSRLLYAEVLLMSPSSPITETADWLMKLILHSDWLLQ
TQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIM
SELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIE
VVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIRDKNKGEAYDRAIDLFTRSCAGYCVATF
ILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQ
ECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALE
KNQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
>A0A673G9M4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus rhinocerous|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVEMRDASGPHSQIIVVIWVIVSPNNDKQKY
TLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLKMCVQEYQGKYILKVCGCDEYLLEKYPI
SQYKYVRSCIMLGRLPNLISTISSLPCQSLTRFYVSFSTIKTKKIESNREIKTQPYYLQC
FNSACFINEHLNDLLQEHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGV
TGSNPNKETPCLELEFDHFSSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDH
AMTEADIEQLRQLSNRDPLSEITEQEKDFLWRHRQYCVNIPEVLPKILLAVKWNSRDEVA
QMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQSEMHNKT
VSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQM
RRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEI
IFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQ
IQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAIDLFTRSCAGYCVATFILGIGDRHNS
NIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFE
RFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDY
FMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
>A0A2I3T7A8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Pan troglodytes|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEECNKLYLNYNLFDDIPEAEYFIKTMNEHIMGWTHKRIV
DLPPIKQHALNLKR
>A0A7L3W4M8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Atlantisia rogersi|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKQGKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNNLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKVKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISVVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHTVTMEIKSVSAEKYDVTSQVITQLRQKLERLQSS
NLPESFRVPYDPGLRAGALVV
>A0A7L0RAA6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Glaucidium brasilianum|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWSAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLESPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIASPPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C3H186|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Corvus moneduloides|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPIKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A4D9EQY5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Platysternon megacephalum|TrEMBL
MPPGIYCPVEFWSKEENQTIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWRHAQYEPLYH
MLNDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVRDPEVNDFRAKMRQFCEEKATKRQQLSWISWMEYNFPLQLEPLAKGPRT
GPLRIPNKNIFVNVKFESGGESFTFQVSPKEFPVTLMSYAIKKQATVFRHQTVESPEDYT
LQVKGKCEYLYGNYPLYQFQYIRSCLHHGLMPHLTMVHFSSVIAMRDEQTNCTAHTPKMV
SKPPPLPKKKPTHETLWSLNQPFYIELVQGSKVNADERMKLVVQAGLYHGNEMLCKMVSS
AEVNVCSEPVWKQRLDFDISICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNIMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQSNPNTESAAALVICFPSVIP
HPVYYPSFEQLLELGRNGEYTRAAPEDPEEKQQLREILERRSHTELYEHEKDLVWKMRHE
IRDQYPEALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFTI
NSLKKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHV
PAVALRFGLVLEAYCRGSNYHMKVLMKQGEALNKMKALNDFIKVSSQKATKPQAKEMMHV
CMKQETYLEALSNLQCPLNPTIILAEVCVDQCTFMDSKMKPLWIVFNNEEAGGRGVGIIF
KNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGEALEEAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRD
YCEKAYMILRCHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVAKDNRQ
>A0A7L0UH93|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chordeiles acutipennis|TrEMBL
MELEDCAQPVVMREENKRRRRRMKPHCTSSNLLSMELISIEFILPTSNKHTKVPETMLLE
IAGNCTVEQMKAQIWMRAIEMSQATDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILHSFFTKIAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIFCGKAQGLSTKMNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDRYCHPVALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLSKKEVWDQSTLDVGLTMQLLDCNFSDESVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFIKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKRHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A669BWM0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oreochromis niloticus|TrEMBL
GQRGMKCTTRGWQAGESYSDCLTQKQCCEVMSHLLWKQAQSFPLFPALGEMESHMFECVN
QAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLDSKIGVLIGKGLHELDALNDQ
EVKDFRCKMFRISEERMQQIQMMTFSEWVQACYSPQLEPAAVTAITAGVNDFPFLQDSAS
LKVSLSCTPNELMEQALKKWLTTHGSEDAVWRGQYILRVSQCLEFLGGDHPLIQYKVISH
KLAKIFCLSLHLWPLSGWLVIVKFNPSCITQVQVRAGLFHGTELLCKPAVSNESSGRSEH
TWKDNTLEFEISVCDLPRMTRLCFAIYAVMDKVKKQKSTKNPHINKYQTIPWVNTMVFDY
KGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATALHIHFPEYSSHPIVFPPF
DKVTQHSIVIFSQINKMIPICPFKTYQLGRGVKKFYMELKEIMERDPVSQLCENEKDLIW
TLRQDCRETFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYV
REYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQRNRQIGHFLFWHLR
SEIHMPAVSVQFALILEAYCRSNIPHIEVLKKQVEALSKLKSVNELIKLGTIKNTRSKTK
EAMLTKEAMMTCLRQSGYSETLSDLHSPLNPSVLLSDINVEKCRYMDSKMKPLWIVYNNK
LLSGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRTGLIEV
VSSAETIANIQLTSSNVAAAAAFNKDALLNWLKERNSGDALDRAIEEFTLSCAGYCVATY
VLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKT
GNTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKT
DEEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A8C8GKB8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus tshawytscha|TrEMBL
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHEVFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKCPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGESSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNRETPCLELEFDYF
SSPVKFPDMTTVEGHANWTISRELGFSYCQSGQSNRVARDHALTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNIRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCMS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDLAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERCLPVT
>M3W2E5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Felis catus|TrEMBL
MELDNYEQPVVLREDNRRRRRRMKPRSTTASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVATDFYRRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCSKAPVLAGKTSAETPSSESKGKTQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTDQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDRIGMIEIVKEATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7M4ERK2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Crocodylus porosus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWSLNSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMFILELPRAARLCLSICSVKGRKGAKEVKC
FRVSVYCQIKLLATKLGKKPWLTHKWNETPCLELEFDWFSSPVKFPDMTVIEEHANWAIA
RELGCNYSHAGLSNRLARDIEVRESDKEQLRAICTRDPLSEITEQEKDFLWSHRHNCVNT
PEILPKLLLSVKWNSRDEVTQMYCLIKDWPPIKPEQAMELLDCNYPDPMVRSFAVQCLEK
YLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVS
QRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRR
PDFMDALQGFISPLNPAHQLGNLRLDECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIF
KNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQ
CKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRSCAGYCVATFILGIGDRHNSNI
MVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQ
EMCCKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMK
QMNDAHQGSWTTKMDWIFHTIKQHALN
>A0A2U3YPT2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptonychotes weddellii|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTMRVPTRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFRVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLNMWPSVPDEKGELLNPTGTVRSNPNTESAAALIICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEELQLREILERRGSGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALSDFVKVSSQKTTKPQTKELMHLCIRQ
ETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDTQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A7K5AM62|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Furnarius figulus|TrEMBL
MELEDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELVSIEFILPTSNKHTKVPEMILLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRLKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNVWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIPSD
AQGDRTRVEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKEKCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6I9L1Z1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Peromyscus maniculatus bairdii|TrEMBL
MCFSSIMPPAMADILDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEDKIQSLVGLSWIDWLKHTYPPEH
EPSVLENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNLTPIKINELAIQKRLTIHGREDE
ANPYDCVLQVSGRVEYVFGEHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYAENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVSCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALDNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYSNRGFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A5J5DK30|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Etheostoma spectabile|TrEMBL
MPPAMTDLLDIWAARSPLAGQALDQITVDFLLPTGIYIQMEVPRDATIQHIKLLLWKKAQ
LFPLFLSLGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRSKMFRLSEERMQQVQMMTCTEWLQACFSPQLEPL
AGTAITDGLSDRPPDLKVIIHFDQSQDSASLKVPSSCIPSDLMELAVKKWLTTHGPEEEA
WLGQYILRVSHCLEFLCGEQPLIHYKYIRTCMQAKESPHLTLVHTSTVKGMFDKEISAIG
AVVSRKSFNPPLPLPPKRRVPTRHVTYLSATFADCFESLEAKVRAGLFHGTELLCKPAVS
SESSGRSDHTWKDSTLEFDLSVCDLPRMTRLCFAIYAVMDKVKKQKSTKNAHINKYQTIR
KAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENAT
ALHIHFPEYSSHSIVFPPFDKILEKAAEIAGASDCVPMGRGGKKFHIELKEIMERDPLSQ
LCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALEL
LDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTHFLLERAQGNRK
IGHFLFWHLRSEIHMPAVSVQFALMLEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLG
TIKNARNKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSGINVERCRYMDSKM
KPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILKLMDLLWKEANLDLRIVPYGCLA
TGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNTGDALDRAIEEFTL
SCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHD
FIHVIQQGKTGYTEKFGSFRQYCEEAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQY
LKDSLALGKTDEDALKQFRQKFDEALRESWTTKVNWMAHNVAKD
>E1C093|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gallus gallus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFVLQYQKKGQWYEIYDKHQLLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGDTPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
SQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGPLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKDRCVIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6Q2XC31|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Esox lucius|TrEMBL
FATLLWKQAQTYPLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTR
NCGRAERLLDSKIGVLIGKGLHELDALPDQEVKDFRSKMFRISEEKMQRVQLMNWSEWLQ
ACFCPQLEPVVGAAAGTDGVNDKQAETSLKVTIHFDQSQDTASLKVCPSTTPSELMEQAL
RKWLTTHGPEEEGRQAQQYILRVSDKLEFLCGDHPLIHGRKYLRKCLNRATVTSRRLLSV
LSAVSAFPFWLNRTLLVRVQVQVRAGLFHGTELLCKPAVSSESSGRSEHVWNRMLEFDIQ
VSDLPRMARLCFAVYAIMDKVKNRSAARHYPIAWVNTMVFDYKGQLKTGDITLHSWSSFP
DELEEMLNPIGTIQTNPYTENATALHIQFPDYIAHPIVFPPFDKVRERGKKFHIELKEIM
ERDPLSQLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQVALLQIWPKLSP
RDALELLDFNYPDQYVREYAVGCLKDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLDR
GQGNRNIGHFLFWHLRSEMHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVN
ELIKLGTIKNVRSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCR
YMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIV
PYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKA
IEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVP
FILTHDFIHVIQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTS
VKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A2K5DEN8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aotus nancymaae|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A2K5CF93|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aotus nancymaae|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGTIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDGLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIILVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEVSGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKAKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYIENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGYWVIYKGKHDEELSQYLLQLVQVLKYEPFLDCALS
RFLLERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALN
KLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCK
YMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRML
PYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRA
IEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVP
FILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTS
VKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3Q3K8F7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Monopterus albus|TrEMBL
MPPAMTDLLDIWVTHSPLAGQASDQITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
KFPLFPALGEMESHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLVTRNCGRAERLLD
SKIGVLIGKGLHELDAINDQEVKDFRGKMCRVSEERMQRVQMMTCTEWLQSCFSPQLEPA
GGTAITDGVSDRPADLKVIIHFDQSQDSASLKAPSSCTTMELMELAVRKWLTTHGPEEET
WRGQYVLRVSHCLEFLLGDHPLIWYKYIRTCIQAKESPHLTLVHTSTVKAMFEQEISTIS
AVVSRKSSNPPLPLPPKRRPPTQVQTCVWDMSSLFKIVLVNCSKVNAEETAKVQVRAGLF
HGTELLCKPAVSGESSGRSDHTWKESTLEFEIAVCDLPRMTRLCFAIYAVMDKVKKQKST
KNAHINKYQTIRKAGKVHYPIAWINTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIG
TIQTNPYTENATALHIHFPDYSYHPIVFPPFDKILEKAAEIAGASDCAPIGRGGKKFHIE
LKEIMERDPLSQLCENEKDLIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQI
WPRLSPRDALELLDFNYPDQYVREYAVDCLRDMSDEELSQYLLQLVQVLRYEPYYDCALT
HFLLERAQRNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRCNIPHIEVLKKQVEALN
KLKSVNELIKLGTIKNARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPLVLLSGI
NVERCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDSLWKEAN
LDLRIVPYGCLATGDRTGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSG
DALDRAIEEFTLSCAGYCVATYVLGIADRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGI
KRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLILRKNGNLFITLFALMLTAG
LPELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7N4PG41|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sarcophilus harrisii|TrEMBL
MPPGVDCPMEFWSKEENQIVEVDFLLPTGVYLNFPVSRNANLSSIKEVLWHNAQSEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVARQGDRVKKLINSQISLL
IGKGLHEFDSLGDPEVNDFRTKMGQFCEEAAAHRQQLGWEAWMHYNFPLQLEPSARGLGA
GALRGPSRTLFVNVKFEGNEESFTFQVSPNDFPLALMACALKKRVTVFRQPALERPEDYT
LKVNGKYEYLYGSYPLYQFQYICRCLHNGQTPHLTMVHCSSILAMRDEQSNFPAQTPKLR
TKPPPIPMKKPSSVSLWALEQPFCIELIQGSKVNADERMKLVVLAGLFHGNEMLCKTVSS
SEVTVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWSSVPGTAALEPEGPVGLGGGCEWGEAQPLLLRPAEPHG
HRLQQLREILERKVAGELYEHEKDLVWKMRHEIQEQFPEALARLLLVTKWNKHEDVAQML
FLLSSWPELPVLSALELLDFSFPDRHVGSFAIQSLRKLTDDELFQYLLQLVQVLARVPPD
RVTVPAGRPHRKIGRSSLSSEMHVPSVALRFGLIMEAYCRGSNHHMKALMKQGEALNKMK
ALNDFVRVSSQRTTKPQTKELMHVCLRQEIYMEALSNLQSPLNPSTLLSEVCVEQCTFMD
SKRSRGSQAAGEAAGSCSPGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLREALERA
IEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVP
FILTYDFVHVIQQGKTNNNEKFERFRSYCERAYTILRRHGLLFLHLFALMRAAGLPELSC
SKDIQYLKDSLALGKTDEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7J8KE87|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rousettus aegyptiacus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRVPSRALLVNVKFEGSEESFTFQVSSKDVPLSLMACALRKKATVFRQSPVEQPEDYA
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIQLIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVNVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALIICLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRASGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQLPQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAI
KSLRKLTDDELFQYLLQLVQVLKYESYLDCELAKFLLDRALANRKIGHFLFWHLRSEMHV
PSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPQTKELLHL
CMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSEGSVGII
FKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANI
QLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSD
NIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFR
GYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRV
KFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C3WNC8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Catagonus wagneri|TrEMBL
MFFRFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPVKINELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDYPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSIGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A340XZ14|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Lipotes vexillifer|TrEMBL
MPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNY
PMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGRGLHEFDALKDPEVNEFRIKMRRFSEEKIQSLVGLSWMDWLKQTYPPEHEPSIPE
NLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHGKEDEVSPYDY
VLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAIEAAINR
NSSNLPLPLPPKKTRIISHVWENNSPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TVVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKAINPSKYQ
TIRKSGKVDYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVGCLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALA
NRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLKTLNSLI
KLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYIEKCKYMDSKMKPL
WLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGD
HSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCA
GYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3Q7MW70|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinus ursinus|TrEMBL
MPPGLDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTLRGPTRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLYQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFRVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEELQLREILERRGSGELYEHEKDLVWKMRHEVQER
FPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSLR
KLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVA
LRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALSDFVKVSSQKTTKPQTKELMHLCMRQ
ETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKNG
DDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGYCE
RAYTILRRHGLLFLHLFALMRAAGLPELSCSKDTQYLKDSLALGKTEEEALKHFRVKFNE
ALRESWKTKVNWLAHNVSKDNRQ
>A0A8D0EE65|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salvator merianae|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMIVVLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEKEEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNIESSSELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEAPAKSLWVINSNLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLQYEMHVLDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMSVIEEHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNMPEILPKLLLSVKWNSRDEVAQMYCLIKDWPPIKPEQAME
LLDCNYPDPRVRAFAIRCLEKHLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFVSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTRXFEXFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8D0B8S6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salvator merianae|TrEMBL
MMPPAMADALDIWAVDSQVAADGSISVDCLLPTGIYISLDVPRDATILHIKQLLWKEAHS
YPLFHLLTEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLQLITRSCDPGDKLDSK
IGVLIGKGLQEFDLLQDPEVKEFRIKMRRISEEKMQSLMGLSWMDWLKQTYPPELEPAIQ
DNLQDKLYSGNLVVAVHFDNCPDVFSFQVSPNINPIKLNELAIRKRLTIYGREDEEVNPH
DYVLQVSGRLEXVFGDHPLIQFQYIHRCVMGRTLPQLTLVECNTIKKMYEQEMIAIEAAI
NRKPSSIPLPLPPKKSRLTQSVWNISHPFKIVLVNGNKLNTEESAKVHVRAGLFHGTELL
CKPVVSTEISGRNDHVWNEPLEFDINVCDLPRMARLCFVVYAVMDKMKNKKSAKTLNPPK
YQTIRKAGKVHYPVAWVNTMVFDFKGQLKTGDLVLHCWSSFPDELEELLNPMGTVQTNPY
TENATALQIKFQEYSKFPIYYPPFDKILEKAADIARNSDSTGMAGRGGKKFYIELKEIME
RDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPP
REALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLEK
ALANRRIGQMLFWHLRSEVHIPAISVQFALILEAYCRGNIAHMKVLSRQVEALNKMKTLN
SLIKLTAVKQSKAKGKDIMHTCLRQRAYREALSDLQSPLNPSVLLSELYVEKCKYMDSKM
KPLWIVYNNKVFGGDLVGIIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLA
TGDHSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGEDLDRAIEAFTL
SCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYD
FIHVIQQGKTGNTEKFGRFCQCCEQAYLILRRHGNLIITLFALMLTAGLPELTSVKDIQY
LKDSLALGKNDEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A3B4U4Y4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Seriola dumerili|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKALWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A8C9IIE4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Piliocolobus tephrosceles|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A4W5LWR9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hucho hucho|TrEMBL
MPPGEYGMLGEWEKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRLFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDTQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLPEP
GGNKTKGTKKIFVNVKFEASDESFMLQQEPQDLPVILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTVVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVV
TSCEVNVCSEPLWDKKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPHFDKVHLLLHTLDNKNYTEFFEDEKELLWKLRGVVRERYPESLSKLLLITKW
NKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTIRCLRKLRDEELLQYLLQL
VQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGN
IYHIKNLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCIKQEAYMEALSYLLSPL
NPSIMLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIFKNGDDLRQDMLTLQMIQL
MEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALL
NWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIKETGQLFHIDFGHFL
GNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECCEQAYKILCRNGTLFVN
LFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMH
SLAKDSRL
>A0A7K9LQY6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Rhabdornis inornatus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKGFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GDYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQEAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6J3R9V8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tursiops truncatus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8C2Z9Z5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyclopterus lumpus|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHQ
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDSVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLDRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYLNGEASAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPCAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHY
SSSVKYPDMNAVEDHANWTISRELGYNYNLSGQSNRSARDHALTESDTEQMRQLSNRDAL
SEITEQEKDFLWRHRHYCMIVPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKVNNFNSYSLFSKMS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A8C7UCK3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oncorhynchus mykiss|TrEMBL
MEQQVSDEEEPQPVVLREEIRRRRRKMKAFTSTFSVAVDQIAVEFVLPTTTKSSRSPDTL
LLEVAGNWTVEQVKAQVWLRVVATNLCPEFYQKYSPDHCILLYQKKGNWCEIYDKHQVFQ
TLDCVRYWKALKKDVGKIHLTCRPQPSEESTQYQRYLNYLIGYDVTDVSNVHDDELEFTR
RKLLTPRKIELSDRDPKLYSMDPWITSKHLPEYLLTKVTNSHILLVIHRNKASQTIKVSI
DDTPVQVLQTFFTKISNKRALLGVPEDVCEADYVLRVCGREEYIYGNHPVRDFHWVRQCL
KNGEEIHLVLESAPNPGQDLVQREDWAQVDDCTGVAGTHEQLTIDEKDHERVYTISLWDC
HRKFRVKILGIDIPALPRNPELIVYVEASIFHGQQLLAQERTSSKAFTEEVLWNAWLEFN
IRIRDLPKGARLSLQVFCGKAQTQISKGTSSYQDNGGSPGGGGSSSHDGSKTKNRLLYYV
NLLLVDHRSLLRQGEFILHMWKMPEKTEDNSSVNADKLTSATNPDKASSMAVAILLDKYC
YPVALPKSREGKAAGGEGREAEGGERGQREMPNHLRKQFEVIVETDPLHPLSQEDKELLW
HFREECMRHPRAYPKLLGSVLWGRQEAVLATHRLLERSSVWDRSVLDVGLAMQLLDCHYS
DAHVRSMAVRKLETLGDDDVLRYLLQLVQAVKFEPYHDSALARFLLKRALRSKRIGHFLF
WFLRSEIAQSMHYQQRYAVLLEAYLRGCGEDMLQDFRRQVEMTEALQKVTREIKAMSAEK
YDVSAQVVFQLRQKLENLQTSGLPESFRVPYDPGLRAGALVIEQCKVMASKKRPLWLQFK
RADPTTLSSDTIGVIFKDGDDLRQDMLILQILLIMESIWEEESLDLSLLPYGCISTGNKI
GMIEIVKDATTIANIQQSVVGSTGAFKDEILNQWLRDKCVSEEKFQQAVERFVFSCGGYC
VATYVLGVGDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLYVMG
TSGKKSSPHFQRFQDVCVRAYLALRHHTNLLVILFSMMLMTGMPQLTSKEDIEYIREALT
VGRPEEEAQRHLLDQIEICRDKGWTVQFNWFLHLVLGIKQGVDKRSA
>A0A7J7V4N9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myotis myotis|TrEMBL
MELESHEQPVVLREDNRRRRRRMKPRGSAASLSSMELIPIEFVLPTSQRTSKTPETALLH
VAGHGNVEQMKAQVWLRALETSAAADFYQRLSPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRRGPSEETLAFQRQLTALMGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVVSRDPQLYAMHPWVTSKPLPEYLLKKIAHNCIFIVIHRSTTSQTIKVSADDT
PGAILHSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRHCLKNG
EEIHLVLDTPPDPAQDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHDSVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIRI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPEARGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKDSSMSICILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEMVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLNYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEILQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSSLP
ESFRVPYDPGLKAGALVVEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWEIESLDLCLLPYGCISTGDKIGMIQIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQEVCTKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7L1TTI3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phainopepla nitens|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSTELIPIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQVWMRAIETSQTTDFYHAFTPEQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFRKITNNNIFIIIHRGTTSQKIKVSIDDT
PGMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNADLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRT
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSE
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADATALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C2TJV8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coturnix japonica|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGAIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLSHTPVKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQVSLLSCFDKRVCPPCTHFSGRVVDGSADEMSSARQVTFLA
MLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIE
KAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPGMSGANRWDLPLT
YCPLYALCCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLTIT
KWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQYLL
QLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCR
GSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQETYLEALSHLQS
PLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMI
QLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDA
LLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGH
FLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYMILRRHGPLF
LHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWL
AHNVSKDNRQ
>A0A8C5MA60|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Leptobrachium leishanense|TrEMBL
MPPAVLDPMDIWAVDAQLHSEISVDVLLPTGIYVQMEVRRDASISHIKQLLWKHAPSYPL
YHLLLEMDSYMFECVNQTAVHEELEDETRRLCDVRPFLPVLKLVSRNCNPAEKLDSKIGV
LIGKGLQEFDALNDNEVKEFRSKMRKISEDKAQSLLRLTWMEWLKCTFPPELEPCVQENI
QDKLYSGNLVVAIHFDNCQDVFSFQVSPNMTPTKVNELAIRKRLTIHGREEEEVDPEDYV
LQVSGRQEYVFGDHPLIQFQYIKSCVMNKSLPRLILVECCNIKKMFDQEISAVELAVKRK
TTGPPLPLPPKTRASTISQSVWSLLEPYKITLIKGSKLSTEDTTVVVRAGLFHGTELLCK
PMSAELSGKSDSLWNAPVEFEINVCDLPRMARLCLAIYTVDKTQKKKGNKTGNPKYQTIK
KAGKMHYPVAWVNTMVFDYKGQLKAGEHVLHGWSSFPDELEEMLNPMGTVRTNPYIENAT
ALHIKFRDHAKAVYYPPFDKILEKAAEIARHSDSLTMSGRGGKKFNIELKEIMERDPLCQ
LCENEKDLIWTLRYDCRENFPCSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPRDALEL
LDFNYPDQYVREYAVNCLKNMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLQRALANRR
IGQFLFWHLRSEVHISTVSVQFGLLLEAYCRGSVAHMKVLSRQVEALNKLRTLNSLIKLN
AMKQSKVKNKESMHACLKQNAYKEALTDIQSPLNPSVTLSELVVEKCKYMDSKMKPLWIV
YSNRGFGGESMGIIFKNGDDLRQDMLALQLLRLMDMLWKESGLDLRIVPYGCLATGDRCG
LIEVVSAAETIADIQLDCSNLAAAAAFNKDALLNWIKEFNAGDDLERAIEEFTLSCAGYC
VATYVLGIGDRHNDNIMVRKTGQLFHIDFGHILGNFKSKFKIKRERGPFILTYDFIHVIQ
QGKPGNTEKFGRFRQYCEDAYLILRRNGNLIITLFALMLTAGLPELSSVKDIQYVKDSLA
LGKTEDDALKQFRQKFDEALKESWTTKVNWMAHTVRKDYNKS
>A0A8C2TIZ2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Coturnix japonica|TrEMBL
SCFNLSRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGAIKQVTALVT
QLHDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLSHTPVKNIFVNVKFHFACCAWSFTFQISPNEFPITLMSYAVKKQATVFRHETMENPED
YTLQVNGKYEYLYGNYPLYQFQVSLLSCFDKRVCPPCTHFSGRVVDGSADEMSSARQVTF
LPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEP
VWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWVNVMLFDYK
DQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNAASHPVYYPSFE
QVGNTDVFLRGFLLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQALAKLLTITKW
NKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQYLLQL
VQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGS
THHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQETYLEALSHLQSPL
NPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQL
MDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALL
NWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFL
GNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYMILRRHGPLFLH
LFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAH
NVSKDNRQ
>A0A8B9UEK3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas zonorhyncha|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8B9TWR1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGFGT
GLLHTPTKNIFVNVKFQSGGVNFTFQIAPDEFPITLMSYAIKKQATVFRHETMESPEDYT
LQVNGKYEYLYGNYPLPRGLTVFSYFFSPQLVVQAGLFHGNEMLCKMVSSSEVNVCSEPV
WKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVSKDCPIAWVNVMLFD
YKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAASLVICFPNVASHPVYYPS
FDKPFGLRLSPLYALFCDSHEQKLQLKEILERRSHTELYEHEKDLVWKMRYDIRDQYPQA
LAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVVFYFAFLSTEITN
CSKYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLI
LEAYCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHVCMKQETYLEA
LSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETSGGGVGIIFKNGDDLRQDM
LTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMVATA
AFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLF
HIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRGYCEKAYMILR
RHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWK
TKVNWLAHNVSKDNRQ
>A0A672ZXA0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sphaeramia orbicularis|TrEMBL
MPPGKYGMQEEWEKEGDQGIMMDFLLPTGIFLKFLVSRNDTIKSIKKMVWKNARSEALFA
ALGDPDAYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFEAQKNHEVNEFRTKMRMFCEEKALDRQRLPWQQWMEYSFPCDLEPCCSPPEC
GNAKSKNTKKLFINVKFEASDESFMLQQDPQDLPVALIRSALKKKATVFRSVRQEPEDYT
LQVNGRWDFIYGSHPLCQYKVSDLLNGQNPHLTMVHHSTISKYQEEQGQMCNQVFKSRSL
SRPPPLPLKKNTSSLWSINEPFYIQLLQGNRVNADEGMKLVVQAGLFHGSELLCKVVTSS
EVTVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWV
NTMVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRQH
PLYYPPLEKVLDPKHFCTGITSMVGLLRNWPELPAIHALELLDYSFPDPAVRSFTIRCLR
KLSDGELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVS
CVFGLILEAYCRGNIHHIKLLTNRYLRTNAQLPQPMTAEDLKLCIRQESYVEALSDLLAR
RSTEQIIFFVKLFMDSKMKPLWMMYRNPFVQGDMVGIIFKNGDDLRQDMLTLQMIQLMEN
LWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDEKLEKA
IEEFTLSCAGYCVATYILGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVP
FILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNLFAMMKAAGLPELTS
FKDIQYLKWNEYLGE
>A0A8C3LLP3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chrysolophus pictus|TrEMBL
MQRNIIWFLSRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVV
WKHAQYEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRV
KKLINSQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPL
QLEPMAKGLGTGLLHTPTKNIFVNVKFQSGGVNFTFQISPNEFPITLMSYAVKKQATVFR
HETMENPEDYTLQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQ
INNRSSPCGFTVSYSFSSPQLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDIN
ICDLPRMARLCFALYAVIEKAKKARSTKKKSKKAVSKDCPIAWVNVMLFDYKDQLKTGEC
CLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALLICFPNVASHPVYYPSFEQVGNTDVF
LRGESLASLQLKEILERRSHTELYEHEKDLVWKMRHDIRDQYPQALAKLLTITKWNKHED
VAQMISLLQSWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQYLLQLVQVLK
YESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMK
VLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQETYLEALSHLQSPLNPSII
LTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDVLW
KQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKS
KNPGDALEQAIEEFTLACAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKT
KFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYMILRRHGPLFLHLFALM
KAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKD
NRQ
>A0A087VHD5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Balearica regulorum gibbericeps|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSIAVDFLLPTGIYINLDVPRDATISHIKQLLWKQA
HAYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMEWLKHTYPPEQEAV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKDDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCAQEMIAIEA
AINRKSSNLPLPLPPKKTRTTTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTIVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGQLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFYVVLKEI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPRDALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7N6F9S7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anabas testudineus|TrEMBL
MPPGKYGMQGEWEKEGDHEIMMDFLLPTGIFLKFPVSRNDTIKTIKRMVWKNARSEALFT
ALGDPDAYVFTCINHTAEREELEEESRRISDVQPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEVQKNHEVNEFRTKMRVFCEEKAQERQRLPWHQWMEYSFPCDLEPCCSPQCG
SSRSKNTKKILINIKFEASDVSRSTDVDPQDPPLVLMRSALKKKATVFRSVRQEPEDYTL
QVNGRWEFIYGNHPLCQFKYIFSCLRNGQNPHLIMVHHSTISKYQEEQGRMCNQVYKSCS
LSRPPPLPLKKVRGQRTVSACVFPLQLVVQAGLFHGSELLCKVVTSSEVTVCSEPLWDQK
LEFDINVADLPRMGRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKT
GEFLLTLTQIDLLNPMGTVERNPNVDSAAGLLIRFANIRPYPLYYPPLDKVLVLKTLYQS
LKCLFVLLCQKQTKSFVKLKEIMDNKNYTEFFEDEKELLWKLRAEVRSSYPESLSKLLLI
TKWNKREDVVQMVSLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCLRNLSDDELLQYL
IQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSEIHVASVSLRFGLILEAYC
RGNIHHIRLLTKQNEALAKMKSLSDFVKSGSQKMTVEDLKLCIRQESYLEALSDLLSPLN
PSIILSGICADKCRFMDSKMKPLWLMYKNPGTQGDMVGIIFKNGDDLRQDMLTIQMIQLM
ENLWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNCSNSAATAAFNKDALLN
WLKSKNPGDKLDQAIEVFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLG
NFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGTLFVNL
FAMMKAAGLPELTSFKDIQYLKDSLCLGKSDDEALKNFKVKFNEALRESWKTKVNWMMHS
LAKDNRP
>A0A7L1FW77|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sylvia borin|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWQQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWADWMEYNFPLQLEPMAKGLGT
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEMPITLMTYAIKKQATVFRHETVQKPEDYT
LQVNGKCEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVAVCSEPVWRQRLDFDIGICDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
YPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C3K9W1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Calidris pygmaea|TrEMBL
LCIRSLMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQ
YEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVIN
SQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLSLCLQ
GSLYSVVLALQESFTFQISPKEFPITLMSYAIKKQATVFRHETVENPEDYTLQVNGKCEY
LYGNYPLYQFQVSFLSCFVNESVPVCPPPPRGPNYGSLWSLEQPFYIELVQGSKVNADER
MKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVI
EKAKKARSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGT
VQCNPNTESAAALVICFPSVASHPVYYPSFEQVGDGDAVLGQKLQLKEILERRSHTELYE
HEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDF
SFPDRYVGSFAINSLKKLTDNELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGH
FLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKASSQK
ATKPQTKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNN
EETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIE
VVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVAT
YVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGK
TNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGK
TDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A7L0Y3E6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Ploceus nigricollis|TrEMBL
MELGDHEQPVVMRDENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIETSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIRDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITES
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A672R732|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sinocyclocheilus grahami|TrEMBL
MPPGVYGMQDVWEREGWQQVNMEFLLPTGIYLNFTVTSSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRMCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGLCHHEFDSQKNHEVNEFRTKMRTFCEERAQVRQMLPWDQWMEYNFPCDLEPCSVVA
QSGKSCSDKKIFVNVKFEGSETDIFSQGPQDLPMFLKQNALRKKSTVFRSAKQEKPEDYA
LQINGRWEFIYGKYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQVSRSR
AQSKPPPLPLKRVRRHFYTGTRSVINRGTTCHLVVQAGLFHGSELLCKVVTSNEVSVCSE
PVWDQKLVFDISASDLPRMSRLCIALYGVIEKTKKRPTKKKNKSSDCPLAWVNTMVFDYK
DQLKTGEFSLSTWPSVPDLLNPMGTVEKNPNIDSTAGLLIRFPNIRPHPLYYPPIEKVNV
FFQHLKLREIVDNKNYTEFFEDEKELLWKLREVVRQRYPESLPKLLLITKWNKHEDVAQM
VGLLRKWPELPAIHALELLDYSFPDPHARSFTIRCLRKLRDDELFQYLLQLVQVLKYESY
LDCDLTCFLLERALANKKIGHFLFWHLRSEMHVSSVSLRFGLILEAFCRGSIFHLKNLMK
QNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIKQDTYMEALSDVVSPLNPSIVLCEL
CADKCKFMDSKMKPLWLMYKNKYDTLGIIFKNGDDLRQDMLTLQMIQLMDVLWKTEGLDL
RMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPGDKL
DQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSKFGINRE
RVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAYKILCRNGTLFVNLFALMKAAGLPE
LSSSKDIQYLMDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHTFAKDNR
>A0A7K7UNP1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eudromia elegans|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSGNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHVFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDTILQSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PPGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQETVAKTYQLLSKKEVWDQSALDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLQDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCVIEEKFQEAVERFVYSCAGYCVATFVLGIGDRHNDNIMITEA
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A556V1B5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bagarius yarrelli|TrEMBL
MPPGIYCDLQDVWENEGREQVTMEFLLPTGIYLSFPVSCSDTIATIKKMLWRNARSEPLF
SILSSPDAYVFTCINRTAEREDLEDEQRRLCEVRPFLPVFRLVAREGDRVEKLINTQISL
LLGKGLHEFDTQKNHEVREFRTKMRSFCEEKSQERQLLPWYQWMEYNFPCDLEPISVASQ
SGKSHTSVKKIFINVKFEASEESFMLQLDPQDLPLVLIKSALRKKATVFRTIKAEKPEDY
TLQVNGRWEFIYGKYPLCRFKYIFSCLYGGQTPYLTMVHHSTVLKYQEEQGGLSNHISKI
RCQSKPPPLPLKKQNTLSLWSIHEPFSINLLHGTRVNADESMKLVVQAGLFHGSELLCKV
VTSSEVSVCSDPVWDQKLLFDIHLCDLPRMTRLCFALYGVLDKPKKQRSTKKKNKKALSE
LNGEKAVATKEEHLKLKEIVDNKNHTEFFEDEKELLWKLRKEMRANYPESLSKLLLITKW
NKHEEVAQIVALLQKWPDLPALHALELLDYSFPDPHVRSFTIRCLRKLRSELHVPSVSLK
FGLILEAYCRGSIHHIKNLMKQNEALNKMKALNDFVKSAFHKSTSRLQIMEDMKVCIKQE
TYLEALSGVVSPLNPSIILSEICGASGPGGMNREEAPGKSPEEMYIQQKVRVLLMLKKMG
SNLTPSEEAFLRNYAGVVHSQMSQLPQHNIDQGAEDVVMAFSRSETEDRRQ
>A0A8C2RDK9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Capra hircus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRIPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKLVVQAGLFHGNETLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARL
CFALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKG
ELLNPCGTVRSNPNTESAAALVIFLPEVAPHPVYYPSLDKILELGRLGEHGRFTEEEQLQ
LREILERRGSGELYEHEKDLVWKMRHEIQEHFPEALARLLLVTKWNKHEDVAQMLYLLCS
WPELPVLSALELLDFSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELT
KFLLDRALANRRIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALS
KLKALNDFVKVCSQKTPKPHAKEMMHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCT
FMDSKMKPLWVMYSNEEAGSDGTVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRM
TPYGCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDR
AIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERV
PFILTYDFVHVIQQGKTNNSEKFERFRGYCETAYTILRRHGLLFLHLFALMRAAGLPELS
CSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q3NMN1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
LYSCGFELTHDEEPEIVHEEFRRRRRKKAFTSSSSTSMDQITVEFVLPTAGWAGNSPDTL
QLEVAGNWTVEQVKGQVWLKAVTMNLSPDFYQRFSPDQCILVYQKKGSVCEIYDKHQVFQ
TLDCIRYWRALKKDVGRIQLVPRPQPSDESQQYQRYLNHLIGYDVTDVSNVHDDELEFTR
RKLLTPRRIELSDRDSKLYSMDPWVTRKPLPEHLLSKVSNGHILLVIHTGTARQTIKVSI
NDTPVLASFFTKTTNKRGLLGIPENMCEADYVLRVCGREEYLYGDQPLQNFNWIRQCLKN
GEEIHLVMEMPPDPDLDLVQKEDWALVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCNR
KFRVKVLGIDIPSLPKIPELIVFIEASIFHGQQLLAQERTISKTFNEEVLWNCWLEFNIK
IRDLPKGARLNLQVNSDIMSEGVSVVEFIAYIFGKTKSRLLYYVNLLLIDHRSLLRQGEF
ILHMWKMPEKSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDV
GAAGEESEGGERGQREMPNHLKKQFEAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYP
KLLGSVRWGKQEDVLITHHLLERSNAWDTSDLDVGLAMQLLDCHYSDAQVRTMAVRKLET
LEDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEISQSMHYQ
QRYAVLLEAYLRGCGEAMLQDYRKQVDMTEALQKVTREIKAMSADKYDVTAQVVFQLRQK
LETLQISGLPESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGI
IFKDGDDLRQDMLILQILLIMESIWETEALDLCLLPYGCISTGNRIGMIEIVKDATTIAN
IQQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHND
NIMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQ
DVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRTEDEAQRHLLD
QIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A3Q3T2Q8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MDRQQIQVSDEEPEIVHEEFRRRRRKKAFTSSSSTSMDQITVEFVLPTAGWAGNSPDTLQ
LEVAGNWTVEQVKGQVWLKAVTMNLSPDFYQRFSPDQCILVYQKKGSVCEIYDKHQVFQT
LDCIRYWRALKKDVGRIQLVPRPQPSDESQQYQRYLNHLIGYDVTDVSNVHDDELEFTRR
KLLTPRRIELSDRDSKLYSMDPWVTRKPLPEHLLSKVSNGHILLVIHTGTARQTIKVSIN
DTPVQVLASFFTKTTNKRGLLGIPENMCEADYVLRVCGREEYLYGDQPLQNFNWIRQCLK
NGEEIHLVMEMPPDPDLDLVQKEDWALVDDCTGVAGTHEQLTIDEKDHERVFTISMWDCN
RKFRVKVLGIDIPSLPKIPELIVFIEASIFHGQQLLAQERTISKTFNEEVLWNCWLEFNI
KIRDLPKGARLNLQVNSDIMSEGVSVTKSRLLYYVNLLLIDHRSLLRQGEFILHMWKMPE
KSEESSSSINADKLTSATNPDKASSMAIAILLDKYCYPVVLPKSRDVGRDVGAAGEESEG
GERGQREMPNHLKKQFEAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPKLLGSVRWG
KQEDVLITHHLLERSNAWDTSDLDVGLAMQLLDCHYSDAQVRTMAVRKLETLEDDDVLRY
LLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEISQSMHYQQRYAVLLEA
YLRGCGEAMLQDYRKQVDMTEALQKVTREIKAMSADKYDVTAQVVFQLRQKLETLQISGL
PESFRVPYDPGLRAGALLIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGIIFKDGDDLR
QDMLILQILLIMESIWETEALDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGST
GAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDNIMITESGN
LFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQYMYVIHPLS
LSQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRTEDEAQRH
LLDQIEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A3Q3KRC4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mastacembelus armatus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERNPCLSFRMPELQSFDDIAYIRKTLALDKSEQEALDYFMKQM
NDAHHGGWTTKMDWIFHTIRQHAMN
>A0A0D9RKI4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chlorocebus sabaeus|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A6P8TLR1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gymnodraco acuticeps|TrEMBL
MPPGKYGMQEEWEKKGDQEIVMDFLLPTGIFLKFPVSPNDTIKTLKKMVWKNARSEALFS
ALGDPDAYVFTCINQTAEREELEEEWRRISDIRPFMCVLRLVAREGDRVEKLTNTQISWL
IGKGLHEFEAQKNHEVNEFRTKMRAFCEEKAQERQMLPWQQWMEYSFPCDLEPCVSPPEY
GSVKSKNTKKMFINVMFEASDESFMLQQDPQDPPVALIRSALKKKATVFRSVRQEPEDFT
LQVNGRWEFIYGKHPLCQFKYIFHCIRNGQNPLVTMVHHSTIRRYQNDQGLCSQIYRNRS
LSRPPPLPLKKQNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSEFLCKVVT
TMEVSVCSEPLWNQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPSVPDDKTDLFNPMGTVEKNPNVDSAAGLLIRFPNIR
PHPLYYPPLDKVGDMEKNDEAANATKEELIKLKVIMDNKNYTEFFEDEKDLLWKLRTEVR
DRYHESLSKLLLITKWNRREDVVQMVSLLSNWRDLPAIHALELLDYSFPDPAVRSFTIRC
LRKLSDAELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLRSEIHVTS
VSLRFGLILEAYCRGNIHHIKLLSKQIEALGKMKALSDFVKSGSQKMTADDLKLCIRQES
YMEALSDLLSPLNPSVILADICADRCRFMDSKMKPIWLMYNPKVQEDMVGIIFKSGDDLR
QDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSA
LLTAAFNKDALLNWLKSKNPEDKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRET
GQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAY
KILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKVNWMMHSLAKDNRP
>A0A6P8NWL9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCIPNGMIVTLECLREATLLGIKHNLFKEARKYPLFH
LLQDESSYIFVGVTQEAEREEFYDETRRLCDLRLFQPILKVIEPVGNREEKILNREIGFA
IGMPICEFEMVKDPEVQEFRRNILSVCKEALDLREASGPHSQALYVYPPNVESTPELPKH
IYNKLDKGLIIVTIWVIVFPNNDKQKYTLKIPHDCLPEQVIADAIRKKTRSMHLSPEQLK
LCVQEYQGKYILKVCGCDEYLLEKYPFSQYKYIRNCITIGRLPHLMLMSKESLYGQLPAN
IFIMPSYARRSVTSCYMNGDVPTKSLWSINSLLRIRILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYLTDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINLFDYKDTLVAGKMALNLWPVPHGLEDLLNPIGVGGSNPNKETPCLELEFSWYT
HAVKFPDTPQIEEHANWSMSRELGLNYCLVGLSNRLARDSSLIENEMEQLRNICNRDPLS
EITEQEKDFLWRHRHYCINIPETLPKLLLSVKWNSRDEVTQMYCLLREWPLIKPELSLEL
LDCNFPDPMVREFALKCLVKGLTDDKLSQYLIQLVQVLKYEQYLDNILARFLIKKALTNQ
RIGHFFFWHLKSEMHSKTVSQRFGLMLEAFCRGCGMYLKHLNRQVEAMEKLINLTDILKQ
EKKDETQKMQMKFLMEQMRRPAYMEALQGFICPLNPVHQLGNLRLEECRIMSSAKRPLWL
NWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIRIMENMWQNQGLDLRMLPYGCLSI
GDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWLKDKNKGEGYDAAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQVRKRKDAMLFHIDFGHFLDHKKKKFGYKRERVP
FVLTQDFLIVISKGIQECTKTKEFERFQEMCYKAYLVIRQQANLFINLFSMMLGSGMPEL
QSFDDIAYLRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPLSEAGHD
>A0A6P8PC17|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Geotrypetes seraphini|TrEMBL
MPPGVYFPADFWAKEQNKNILIDFLLPTGIYITFSVPRNASLGNIKQSLWHHAQYEPFYH
MLSEPQAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVQKLINSHISLL
IGKGLHDFDSVGDLEVRDFRSKMRQFCEEKAAERQQLGWEAWMEYSFPLQLEPSARLLKM
GIFHINSKNIIVNIKFESSEESFTLQISAKEFPLALVRSALKKKAIVFRQQNKEEPEDYT
LKVNGCSDYIYGQYPLCQFKYISGCLYHNLTPHLTLVPTKSIKELRDEQENLSLQVSKLR
SKPPPPPLPVKKLSPVSLWNFEQAFCVKILQGSNVNADECLKLVVHAGLFHGNEMLCKAV
RTAEVSESSEPIWNQMMEFDIGICDLPRMSRLSFILYAVEKTKKARSTKKKSKKADCPIA
WVNTMVFDWKDMLKTGECCLYMWSSAPDDKGELLNAMGTVQSNPNTESAVALRICFPSIS
QHPVYYPPFEKILELGKAGEQQCSTVDEQQQLKELLERRGSVELYEHEKDMLWKLRHEIR
EQYSEALARLLLITKWNRHEDVAQMLYLLQSWPELPVLFALELLDYNFPDRCVRAFTVNC
LKKLSDEELCRYLLQLVQVLKYESYLDCELTTFLLERALANRKIGHYFFWHLRSEIHVPA
VALRFGLLLEAYCRGSHYHMKVLVKQVEALTKMKALNDIVKISSQKATKPQTKEVMHVCL
KQENYLEALLNLQSPLNPSVILGNVCVDLCTFMDSKMKPLWIMYNNEMNQNHVGIIFKNG
DDLRQDMLTLQMIHLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEIVGNSDTIANIQLNK
SNMVATAAFNKDALLNWLKSKNPGVALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKPNNNEKFERFRNYCE
KAYMVLRLHGPLFLHLFALMKAAGLPELSCSKDIQYLKVKQCSG
>A0A8D0JJP4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sus scrofa|TrEMBL
MPPGVDCPMEFWTKEENQSVDVDFLLPTGVYLNFPVSRNANLSTIKKHCLNSRPENPPRF
QFSAPPPPPVSVCVWGAPPRRQQLGWEAWLQYSFPLQLEPSARSWGPGTLRVPNRALLVN
VKFEGSEESFTFQVSTKDVPLALMPLVEQPEDYTLQVNGKHEYLYGSYPLCQFQYICSCL
HSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRTKPPPIPMKKLVVQAGLFHGNETLCK
TVSSSEVSVCSDPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADC
PIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRSNPNTESAAALVIFLP
EVAPHPVYYPSLDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRH
EVQEHFPEALARLLLVTKWNRHEDVAQMLYLLCSWPELPGGGGPSCLLASGVSRRWVQPG
REGLCGPPGEAQPPLPPSSSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLK
ALNDVVKVSSQKTTKPQTKELMHLCMRQETYLEALSHLQSPLDPSILLAEVCVEQCTFMD
SKMKPLWVMYSNEEAGSDGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPY
GCLSTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIE
EFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFI
LTYDFVHVIQQGKTNNSEKFERFRGYCERAYAILRRHGLLFLHLFALMRAAGLPELSCSK
DIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
>U3I7B7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anas platyrhynchos platyrhynchos|TrEMBL
MPPAVTDSLDIWAVDSQIGADGSISVDFLLPTGIYINLDVPRDATISHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPVIPE
NFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNMNPIKLNELAIRKRLTIHGKEDEDIDPAD
YVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEAAIN
RKSSNLPLPLPPKKTRATTSVWDVCSPFKITLLKGNKLNTEENAKVHVRAGIFHGTELLC
KTVVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNPSKY
QTIRKAGKVHYPVAWVNTMVFDYKGQLRNGEFVLHSWSSFPDELEEMLNPMGTVQTNPYI
ENATALHIKFQEYSKHPINYPPFDKILEKAAEIARSSDNAAMAGRGGKKFFVVLKEIMER
DPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKLLPR
EALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERA
LANRRIGQMLFWHLRSEVHIPAVSIQFGLILEAYCRGSVAHMKVLAKQVEALNKMKTLNS
LIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDSKMK
PLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDILWKEAGLDLRILPYGCLAT
GDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEFTLS
CAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDF
IHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDIQYL
KDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A7K6MSC9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Panurus biarmicus|TrEMBL
MPPGIYCPTEFWAKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGRGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQIPTRNIFVNVKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRHETVQKPEDYT
LQVNGKWEYLYGNYPLCQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCISSPPKAA
SKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVSVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A6B0QVK4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Bos mutus|TrEMBL
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRVLLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGEHCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A2I3GMU0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nomascus leucogenys|TrEMBL
MELENYEQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLHYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIIIHRSTTSQTIKVSPDDT
PGDILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNR
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGIPGK
>A0A3M0JT86|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hirundo rustica rustica|TrEMBL
MPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQLLQDESSYIFVSVTQ
EAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPE
VQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKHIYNKLDKGQIIVVIW
VIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVC
GCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLDTFTMPSYSRRISTAT
PYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQR
VPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINMFDYTDT
LVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSNPVKFPDMTVIEEH
ANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPLSEITEQEKDFLWRHR
HYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAMELLDCNYPDPMVRAFA
VRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTNQRIGHFFFWHLKSEM
HNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFL
VEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQ
NNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSH
TIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRSCAGYCVATFILGIGD
RHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTR
EFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEA
LEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A0S7MFT5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Poeciliopsis prolifica|TrEMBL
EEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFAIGMPICEFDLVKDSEVQDF
RRNILNVCKEAVDLRDNNGCHSRALYVYPPNVESSAELPRHIYNKLDKGQIIVVIWVIVS
PSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTQE
>A0A8C0TS12|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Canis lupus familiaris|TrEMBL
MCFNFIMPPAMADILDIWAVDSQLASDGSIPVDFLLPTGIYIQLEVPREATISYIKQILW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNDFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQISPNMNPIKINELAIQKRLTIHGKEDE
VSPNDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFMLVECCKIKKMYEQEMIAI
EAAINRNASNLPLPLPPKKMRIISHVWENNNPFQIVLVKGNKLNTEESVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKNI
NPCKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNKAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRDDLDR
AIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERV
PFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELT
SVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A5N3V0P3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Muntiacus muntjak|TrEMBL
VTQGMELENHEQPVVLREDTCRRRRRMKPRSTAASLSSMELIPIEFVLPTSQRNTKTPET
ALLHVAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVV
QTLDCLHHWKVVHRSPGQIHLVQRHAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFT
RRLLVTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIIIHRSTTSQTIKVS
ADDTPGTILQSFFTKMAKKKSLMDIPESQNEEDFVLRVCGRDEYLVGETPIKNFQWVRQC
LKNGEEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWD
CDRKFRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEF
SIKIKDLPKGALLNLQIYCGKAPVSSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLR
HGEYVLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTP
DPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSV
KWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDV
LHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVI
LEAYLRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQN
LNLPQSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGD
DLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTV
GNTGAFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISE
TGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKA
YLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCR
DKGWTVQFNWFLHLVLGIKQGEKHSA
>A0A5A9NFI7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Triplophysa tibetana|TrEMBL
MPPGVYGMQDVWEREGRQQVNMEFLLPTGIYLSFPVACSDTISTIKKMLWKNAKDEPLFS
ALSDPDAYVFTCINMTAEREELEDEGRRLCDVQPFLPILRLVAREGDRVEKLITTQISSL
IGKGHHEFDSQKNHEVNEFRTKMRAFCEERAQERQMLPWHQWMEYNFPCELEPCSTASHS
GTSRSVKKFFVNVKFEGSEETFVLQQVHQDLPIALKQNALRKKSTVFRSAKQDKPEDYTL
QVNGRLEFIYGKYPLCQFEYIFSCLHGGITPHLTMVHHSSICKYQEEQGGLSNQVSRSRA
QSKPPPLPLKRQNTCSLWSIQEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SSEVSVCSDPVWDQKLVFDISVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEYSLSSWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFANIRP
HPLYYPPIEKQQKLKEIVDNKNYTEFFEDDKELLWKLRAEVRQHYPESLPKLLLITKWNK
HEDVAQMVCLLRKWTDLPALHALELLDYSFPDPHVRSFTIRCLKKLRDGELFQYLLQLVQ
VLKYESYLDCDLTSFLLERALANKKIGHFLFWHLRSEMHVPSASLRFGLILEAYCRGSIY
HIKSLLKQNEALNKMKALNDFVKSGSQKATRLQTTEDMKVCIKQDTYMEALSDVVSPLNP
YILLCEICADKCKFMDSKMKPLWLMYKNKYDTVGLIFKNGDDLRQDMLTLQMIQLMDVLW
KREGLDLRMLPYGCMSTGNKTGLIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKS
MNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKS
KFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRKCCEQAYKILCRNGTLFVNLFVLM
KAAGLPELSSSKDIQYLKDSLALGRSEDDALKNFKVKFNEALRESWKTKRPLAARAPLLQ
ELIQQQRVYVLDSLQRYRLSGCDPGTGRLFIHDTALIYNKTDRTLDQESGASGAGGMNRE
EAPGKSPEEMYIQQKVRVLLMLKKMGSNLTPNEEAFLRNYAGVVHSQMSQLPQHPIDQGA
EDVVMAFSRSEAEDRRQ
>A0A7L0DUM9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Trogon melanurus|TrEMBL
LAQVVWKHAQYEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAR
EGDRVKKVINSQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWME
YNFPLQLEPMAKGLGTVPLHTPSKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQ
ATVFRHETVENPEDYTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIA
MRDEQTNCIASPPKMVAKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQ
AGLFHGNEMLCKTVSSSEVNVCSDPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKA
RSTKKKSKKADCPIAWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPN
TESAAALVICFPSVASHPVYYPSFEQLLELGRNGEPPRAVPEDPEEKLQLKEILERRSHT
ELYEHEKDLVWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALE
LLDFSFPDRYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNR
KIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKV
SSQKATKPQTKEMMHVCMKQETYLEALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWI
VFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKT
GLIEVVMHSDTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGY
CVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVI
QQGKTNNNEKFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSL
ALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C4F3G7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dicentrarchus labrax|TrEMBL
FCLVSDEEPRVLREENRRRRRKKAITSSSSSSMDQIAVEFVLPTTARGGNSPDTLQLEVA
GNWTVEQVKAQVWLKAVTLNLCPDFYQRLSPDHCILLYQKKGNVCEIYDKHQVFQTLDCI
RYWRALKKDVGRIQMVPRPQPSDESLQYQRYLNNLIGYDVTDVSNVHDDELEFTRRKLLT
PRRIELSDRDPKLYSMDPWVTRKPLPEHLLSILCCYRLYRIKSWVGNGNILVVIHIGTAS
QTIKVSIDDPPVLASFFTKTANKRALLGIPENMCEEDFVMRVCGRYEYLYGDKPLQNFNW
IRQCLKNGEEIHLVLESPPDPELDLVQKEDWAQVDDCTGVAGTHEQLTIDEKDHERVFTI
SMWDCNRKFRVKVLGIDIPSLPKIPEFIVFIEASIFHGQQLLAQERTSSKSFNEEVLWNC
WLEFNIKIKDLPKGARLNLQGGSTYQDNTAVTGKTKSRLLYYVNLLLIDHRSLLRQGEFI
LHMWKMPEKSEESSSSINADKLTSATNPDKASTMAIAILLDKYCYPVVLPKSRDVGRDIG
AGGEEAEGGERGQREMPNHLKKQFAAIVATDPLHPLSPEDKELLWHFRHECMRDPRAYPK
LLGSVRWGKQEDVLATHRLLERSSAWDSSGLDVGLAMQLLDCHYSDAQVRSMAVRKLETL
GDDDVLRYLLQLVQAVKFEPYHDSALVRFLLKRALRSKRIGHFLFWFLRSEIAQSMHYQQ
RYAVLLEAYLRGCGEDMLQDFRKQVEMTEALQKVTRDIKAMSADKYDVTAQVVFQLRQKL
EALQLSGLPKSFRVPYDPGLRAGALVIEQCKVMASKKKPLWLQFKRADPTTLSKDPIGII
FKDGDDLRQDMLILQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANI
QQSVVGSTGAFKDEILYQWLRDKCVSEDKFQQAVERFLYSCGGYCVATYVLGIGDRHNDN
IMITESGNLFHIDFGHILGNYKSFMGISKEWVPFVLTPDFLYVMGTSGKKSSPHFQKFQD
VCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGRSEDEAQRHLLDQ
IEICREKGWMVQINWFVHLVLGIKQGVEKRST
>A0A3B3R2Q7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Paramormyrops kingsleyae|TrEMBL
MPPGVYGLQGIWEDGGQQVDMDFLLPTGIYLNFAVSRNDTIRTIKKIVWKNAKKEPLFYA
LSDPDAYVFTCINHTAEQEELEDEQRRLCDVQPLMPILRLVAREGDRVEKLITSQISLLI
GKGLHEFDSLKNQEVHEFRTKMRAFCEERALDRQRLPWQKWMEYSFPCELEPCPLSGTLK
TQGIKKIIVNVKFEASDESFTLQVEPQEVPLTLIRNALKKKATVFRPMKQEKPEDYTLQV
NGRWDYIYGNYPLCQFKYIFNCLCTGLTPHLTMVHHSTINKFQEEQGGMNSQVSKNRPPT
KPPPLPLKKQTTSSLWSIQDPFVLHLVQGSRVNADEGMKLVVQAGLFHGSELLCKVMTSS
EVNVCSEPVWDQKLEFDISVCDLPRMARLCFALYAVTEKSKKPRSTKKKNKKADCPLSWV
NTMVFDYKDQLKTGEYNLSMWPSVPDDKSELLNPMGTVEINPNTESAAGLLIRFPNIRPH
PIYYPSLSKTYDIRINGNRAEATKEEHMKLREIVENKNYTEFFEDDKEILWKLRYEMFEK
YPESLSKLLLITKWNKHEDVAQMVSLLQLWPELPALHALELLDYSFPDPNVRSFTIRCLR
RLSDNELFQYLLQLVQVLKYEPYLDCELSKFLLQRSLSNRKIGHFLFWHLRSEMHVPSVG
LCFGLILEAYCRGSIYHMKALMKQNEALNKMKSLNDFVKSASQKGTRTQTTGDMKVCIKQ
EAYLEALSDLLSPLNPSLILSEICPDICKYMDSKMKPLWLVYKNEKVQGEPLGIIFKNGD
DLRQDMLTLQMIELMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRNNS
NNAATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIR
ETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCEL
AYKILCRNGTLFVNLFSLMRAAGLPELSSSKDIQYLKDSLALGRSEEEALKNFKVKFNEA
LRESWKTKVNWMVHSVSKDNR
>A0A3B3QP69|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Paramormyrops kingsleyae|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMIVALECLREATLITIKHELFKEARKYPLHQ
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDLEVQDFRRNILNVCKDAVDLRDANGPHSRALYVYPPNVESSSELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQCKYILKVCGCDEYLLEKYPLSEYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
TFTMPSYARRISTATPYMNGEASCKTLWSISSTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLQYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVAGSNPNKETPCLELEFDFF
NCPVKFPDMATVEEHANCTISRELGLNYCQSGLSNRLVRDNALTDNDTEQLCQVCNRDPL
SEITEQEKDFLWRHRYYCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVIPPLSKIYGSVSQSGPRGPTDSPHFRSLPSLRRELEECRIMSSAKRPLWL
NWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSI
GDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDLAIDLFTRSC
AGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL
IVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAY
IRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A673XAM9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPAMTNLMDLWAAHSQLSGEDLVTVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQSY
PLFPSLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFWPMLKLVTRNCGRAERLLDSK
IGVLIGKGLHELDALQDQEVKDFRSKMFRISEEKMQQVQLMTWSEWLQACFSPQLEPGGG
ATPVTDGVNDKQAEASLKVTITSPSELMEQALRKWLTTHGPEEEGRQAEQYVLRVSDKLE
FLCGDHPLIQYKVQVRAGLFHGTELLCKPAVSSESSGRSEHVWNSTLEFDITVSDLPRMT
RLCFAVYAVMDKVKKHARVQTHTDIYLSWVNTMLFDYKGQLKTGDIILHSWSSFPDELEE
MLNPIGTIQTNPYTENTTALHIHLPDYNPHPILFPPFDKGRGGKKFHIELKEIMERDPLS
QLCENEKDLIWTLRYDCMENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALE
LLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTRFLLNRAQCNR
NIGHFLFWHLRSEMHMPAVAVQFSLILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKL
GTIKNARSKTKEAMLTKEAMMTCLRQSGYTETLSDLHSPLNPSVLLSGINVEKCRYMDSK
MKPLWIVYNNKLLGGDTLGIIFKNGDGTRGCISMVLIMNHWNKMCLCRIVPYGCLATGDR
SGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKEKNSGDALEKAIEEFTLSCAG
YCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHV
IQQGKTGNTEKFGSFRNYCEQAYLILRRNGNLFITLFALMLTAGLPELTSVKDIQYLKDS
LALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVVKDNRS
>A0A667WCE5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myripristis murdjan|TrEMBL
MPPGKYGMQAEWEKEGDHKIMMDFLLPTGIFLKFPVSRNETIKNIKKMVWRNAATEPLFS
ALGDSDAYVFTCINQTAEREELEDESRRISDVLPFMCVLRLVAREGDRVEKLTNTQISLL
IGKGLHDFEAQKNHEVNEFRSKMRSFCEEKALERQLLPWHQWIEYSFPCELEPCSSLPES
GNTKSKNTKKIFVNIKFEASDESFMLQQDPHDFPVSLMKNALKKKATVFRLVRQEPEDYT
LQVNGRWDFIYGKHPLCQFKYIFSCLRNSQNPHLIMVHSSTINKYQEEQGTMCSQVSKSG
SLSRPPPLPLKKLVVQAGLFHGSELLCKVVTSSEVAVCSEPLWDQKLEFDINVADLPRMS
RLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDD
KSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPPHDKVLNPKHLYLSLKEIMDNK
NYTEFFEDEKELLWKLRAEVRDRYPESLSKLLLITKWNKREDVAQMLSLLRNWPDLPALH
ALELLDYSFPDPTVRAFTIRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERAL
SNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAYCRGNIYHIKVLSKQNEALGKMRALSDF
VKTGSQKMTAEDLKLCIRQESYLEALSDLLSPLNPSIILSEICADKCRFMDSKMKPLWLM
YKNQWVQGDMVGIIFKNGDDLRQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKTG
LIEVVKNSDTIANIQRNNSNSAATAAFNKDALLNWLKSKNPEDKIDQAIEEFTLSCAGYC
VATYVLGIGDRHNDNIMIRETGQLFHIDFGHILGNFKRKLGINRERVPFILTYDFVHVIQ
QGRTNNSEKFERFRECCERAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLA
LGKSEEEALKNFKVKFTEALRESWKTKVNWMMHSLAKDNRP
>A0A8J4LI82|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Aptenodytes patagonicus|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQKRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGNRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEVVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLDSLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDICVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIREALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A674BYA9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Salmo trutta|TrEMBL
MPPGEYGMLGEWKKEGDHDIMMDFLLPTGIFLKFPVSRNDTIGAIKKMVWRNASSEPLYG
ALSDADAYVFTCINSTAEREELEDETRRLCDVRPFMSVLRLVAREGDRVEKLTNTQISLL
IGKGLHEFDSQKNHEVNEFRAKMRSFCEEKAQDRQRLPWYQWMEYSFSCDLEPCVSLAEP
GGIKTKGTKKIFVNVKFEASDESFMLQQEPQDLPMILMRSALKKKATVFRSVRQEKPEDY
TLQVNGRWEFIYGKYPLCQFKYIFSCLRGGQTPHLTMVHHSTIVKYQEEQGCLGSQVSKS
RSLSKPPPLPVKKNTSSLWSIEEPFHIHLLQGYRVNADEGMKLVVQAGLFHGSELLCKVV
TSGEVNVCSEPLWDQKLVFDISVSDLPRMSRLCFALYAVIEKAKKPRSTKKKNKKADCPL
AWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGTVEKNPNVDSAAGLLIRFPNI
RPHPLYYPHFDKVHLILHTRFNSRHCTFHMKLKEIVDNKNYTEFFEDEKELLWKLRGVVR
ERYPESLSKLLLITKWNKHEDVAQMVAFLQKWPDLPALHALELLDYSFPDPMVRSFTIRC
LRKLRDEELLQYLLQLVQVLKYESYLDCDLATFLLERALSNKRIGHFLFWHLKSEMHVSS
VSLRFGLILEAYCRGNIYHIKSLWKQNEALNKMKALNDFVKSGWQKTSRQQMTDDMKLCI
KQEAYMEALSYLLSPLNPSIKLSEICADRCKFMDSKMKPLWLMYKNKWVQGDAVGIIFKN
GDDLRQDMLTLQMIQLMEILWKKEGLDLRMIPYGCLSTGNKTGLIEVVKNSDTIANIQRN
NSNSAATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIM
IKETGQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRECC
EQAYKILCRNGTLFVNLFAMMKAAGLPELSSFKDIQYLKDSLALGKSEEEALKNFKVKFN
EALRESWKTKVNWMMHSLAKDSRL
>A0A3Q3DCD5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Hippocampus comes|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYNKLDKGGRGFIDHFLTSTLTCLSLAVLGQIIVVIWVIVSPNNDKQKYTLKINHDCVPE
QVIAEAIRKKTRSMLLSPEQLKMCVQEYQGKYILKVCGCDEYLLEKYPISQYKVSHMLAE
FASSSQFGQTASLEVISQKMTSRNSSDR
>A0A2K5U1Y5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca fascicularis|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDVCFPLDLRQDMLTLQMLRLMDLLWKEAGLDLR
MLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLD
RAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRER
VPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPEL
TSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A0P6J4N7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Heterocephalus glaber|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIAVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHSYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEEKIQSLVGLSWIDWLKQTYPPEH
DPSILENLEDKLYGGKLIVAVHFENSQDVFSFHVSPNVNPIKINELAIQKRLTIHGKEDE
ASPGDYVLQVIGRVEYVFGDHPLIQFQYVRNCVVNRALPHFVLVECYKIKKMYEQEMIAI
EAAINRNSSNFPLPLPPKKTRIISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNETLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYHYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAISVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCIILSELYIEKCKYMD
SKMKPLWLVYTNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSDEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>G1NSK5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Myotis lucifugus|TrEMBL
MCFNFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISNIKQQML
WAQIHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPG
EKLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPE
HESSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHWKED
EVSPYDYVLQISGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIA
IEAAINRNSSNLPLPLPPKKRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHVWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NASKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAISIQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A8C9B6B5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phocoena sinus|TrEMBL
MELETHEQHVVLREDNRRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLSPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRLAPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRVAEVAGRDTKLYAMHPWVTSKPLPECLLKKITNNYIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIRNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDHK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKAEDHGSINADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCSFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIDMLQKVTMDVKSLSAEKYDVSSQVISQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIERCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSRHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7L2Y4S8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Erpornis zantholeuca|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQQQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHDRVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLPSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESVKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEAWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLEGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A0A1U299|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Entamoeba invadens IP1|TrEMBL
MSDPYQFSFKPIKKYSTVNFYSPLSAEAEGQRQNPNAQYQQPAQVYSDQSRNVPMYSFAA
STPTHPSQQYQTQPSFQSLSVTQQMTTSFPQQDQLKQYKEYESPFDRTCEVNGMTQQNTL
NQTSVQNEISLDGLDTQDPQHINPLEFFQRNFTSFDPISFSITDSFLAICNTQQDETDAK
RLSYTTALTKVTRYTVSPLDYKYTPSYVLSPDDIYLRVMVDYAQNLRIKYPFPLRRAPLL
NKLAYMAVINKLLSTYNDAMRNSSLIAKFSFHDVSFKPITPEARTTGPNEVTLIFKSDLT
VNKLFELLGVTSTDAVLAIEDTTAIFCRKDIVIQSQYIYDCVTHNTLPTFAVKKYSKMFY
PPKQSLKKEIVQYSFQEMPTSMTITSYFSFDFNQFYYTQSDVGDICVRAVLRCGEQILSP
IFSETSTRNFSRVSAFSPSDSEYVYVVNLGISIPTQIQIRELPLDTQIVIHVISSKNETS
LGCANFNLYDQWGVFKTGRHVLRLESGKIPAGTVMTHGPLLFIDVKNIRCAYHIDGIPDE
KLMTTTRTIEPCTVATNRIQFEESAQVDDLASISKINRVVKKTLLIGETDVFEILRSPIY
ITKSAPPKMSEILVKEMENIPAEFLLHVAHAIHWSDRKEVGRFITYMWTLDLKMTDAVIM
LSYRCPYRAVREFCASIIMKQSDEVLAFYAVHLSEALRFEEGLTALTDVLLKRCVRSPAT
VGYWVLRAICGDCDMTCRHIQHARFIEALLSADPVFAEYISQEEVLFCNLQSVNATLIRM
GSDNRKTLGVAVLQKICKTCPVPFFPGTKGMLESSKMKVFTSNASPIMVDLNGKKMIFKL
GDDLRQDCLILRAFQLFDDIWKNEGKDYRMSPFRVISSGNLSGLIEFVKDSRSLGAIHNE
SKIPGVFKVTSISDWIRENHSAPIEQCVDNWYWSLVGYCVASYVLGLADRHNDNILVDKS
GHFLHIDFAHFLGNKLKVAGVINREPAPFVLTRSMLFVFAGESGTAFYDQKYSEFCDDCV
KAYSILRNKASLIVSFFTNMITSKLSQLSELKDAEYLYESLQIGKEDSIANGFFVSLINE
SLNSEETNVNFFIHSLVQKSKK
>A0A0A1UEJ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Entamoeba invadens IP1|TrEMBL
MAELKRSDYIIASPFRRTTWSGLPLAPLPKRIEVKPLSSGITPSPLSLLRKEDLDQVNDK
KEPRPTNINVIVDENTVFVAVKDRNGKFYAYAMNTNDIGTSVIETCKSNVYIKGDYALTL
PDLQYRVSDEDSRKPLKDLKFIQGCNFHGVVPYFFLVERKAVLQYQSVELVGDYLLQSTM
KYDIIQNNFVELCRKFGEEFYKFRRSLAGVCGKEEEALSKFDKYLLEENEYVYCGNEPPI
QDLNKRLMMKGFLLEQSMDKTISHMPTDTVENVISSLFTKFTITNKGAFAASEKAEDFVL
KVRGLHEFLVPKKRDGTLYTLAEFDYIRRCVLKGEKIELYLKPRKMLHQFLGPLNPNDAK
FDGVYNTLLSHNLWEKVETERTSQPQSSIDRNYFITLKKLTNCVYYKPLPQKKTKENKDE
PPVQEYQNIVSFRAYVTAALFHGPRQLGKQFTTQVFQVNNGTVNLDIAIEFDLKISVLPK
ETKLVIGVFQTEEQIGTVVEHEKKEKSRDNPIGTINCKVVDHNSMLLMGSVQCGLWEMAS
PNFISMCSENVGDKAIYLTFTYPTYEVPIIMDAFNDDSVKSDKDIEKLTADQTKKFKIAL
ESNPLQKLTEDETELIWKLRYTVKKTKPKNLSRVVAAVDLTNVHMVAELHRLIADWPLLD
PQTAIEMLDFKFPDQKVRDFALKCLEPMDDAELIMFLPQLVQALKFELHHSSELAFFLLR
RALRNKNRIGHQFFWFLKAELHDNRVTERYGLLLEAFVGCCGKYQLELLNEVNFQIALID
IANHVKLLATKDEQKQYLYEQLAKVKLPENQALPIDSRMRFTKPVPNSGNVFSSKKKPLL
LILQNLDPAGEDLCVIQKVGDDLRQDILTLQILRIMYSMLKNAELDVRMLPYQCIATGNE
TGMLELVKNSETYGKIIADDGRRLAVTKSDVLTLWMQKQCSRPESKVSFEQAVDNFVHSC
AGYCVATYLLGIGDRHSDNVMLTREGVFFHIDFGHFLGNFKSKFGVKRERTPFKFTTHFA
DLMGFKDGVESEHFKEFKELCSSALLSLRKQGSLFIYLFRLMLATGIPELRSEDDIEYMK
NAFMFEADDQQVKSNFDAKIYECLDAWSQTLNDLIHDIVHYK
>A0A811ZK61|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Nyctereutes procyonoides|TrEMBL
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYCFPLQLEPSARSWGP
GTLRVPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMR
QEAYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A3Q2FNV0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinodon variegatus|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLVTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGSHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTQEQLK
MCVQEYQGKRTTTNSRERHTKDQSQLLFVCALPLEV
>A0A7L0LCL1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sylvietta virens|TrEMBL
MPPGIYCPTEFWSKGENQSIQVDFLLPTGIYLNLSVPCNASLGTIKQVLWKQAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVLNSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GSLQISTKNIFVNVKFQSGGESFTFHISPWEFPITLMSYAIKKQATVFRHETMQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGLTPHLTMVHSSAIIAMRDEQSNCITSPPKAA
AKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGHEMLCKTVSS
SEVAVCSEPVWRQRLDFDISVCDLPRMARLCLALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRFD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKTTKPQTKEMMHM
CMKQETYREAFSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGEALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDDEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C8E2U2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oryzias sinensis|TrEMBL
MHPGIYGMLEEWEDGDQEINMDFLLPTGIFLKFPVSRNDTIKHIKEMVWRNARSEALFSG
LGDPDGYVFTCINQTAEREELEEEFRRIRDVKPFMCVLRLVAREGNRQEKLTNTQITQLI
GKGLHEFESQKNHEVNEFRTKMRTFCEEKALERQYLPWQRWLEYSFPCDLEPCRTPSGFG
SVKLKSSKIFINVKFEASDVSVEVVMTHVHSALKKKATVFRSLRQEPEDYILQVNGRWDF
IYGKHPLCQFKVSRENKLKHLYMYIQHKKRKNLIFDSFPQQNTSSLWSINEPFYIQLLQG
SRVNADEGMKLVVQAGLFHGSELLCKVVTSLDVTVCSEPLWDQRLEFDINVCDLPRMSRL
CFALYAVIEKTKKPKSTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSMWPSVPGIDL
LNPMGTVEKNPNVDSAAGLLIRFPNIRPHPLYYPSLEKIIDFEKNGDVHLKLKEIMDNKH
YTEFFEDEKDLLWKLRTEIREHYPENLSKLLLVTKWNKREDVVQMVSLLKKWPDLPAIHA
LELLDYSFPDPAVRSFTVRCLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALS
NRRIGHFLFWHLRSEIHVASVSLRFGLILEAYCRGNIHHIKILNKQNEALAKMRALSDFV
KSGSQKMTVEDLKLCIRQETYMEALSDLLSPLNPSIILTEICADKCRFMDSKMKPLWLMY
KNPSTPGDMVGIIFKNGDDLRQDMLTLQMIQLMENMWKKEGLDLRMIPYGCLSTGNKMGL
IEVVKNSDTIANIQLNSSNSAATAAFNKDALLNWLKSKNPGDKLEQAIEEFTLSCAGYCV
ATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQ
GRTNNSEKFERFREYCEQAYKILCRNGMLFVNLFAMMKAAGLPELTCFKDIQYLKDSLAL
GKSEDEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRA
>A0A4Z2CAS5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu bimaculatus|TrEMBL
MTHTDISDISVNYGVVSVQESITGRSPQSQVTELLLSFETTRNRAAFLLRPITESVQRSL
WLRWLAVPLAMPPAMTDLLDIWATHAPLAGHDPDQITMDFLLPTGIYIQCDVPRVATIKE
IKQLLWKEAHSFPMFSKLGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTR
NCGRGERLLDSKIGVLIGKGLHELSAINDQEVKDFRSKMTRISEERMQTIERMTCTEWLQ
ASYSSQLDVPADTTTMDGTDRPADLKVIIHFDQSLDSASLKMASTCTPRDLITQAVRKWL
TTHGPEEDALRGQYVLRVSHCLEFLCGDHPLIQYKYIRTCMQAKEPPHVTLVHNNTIKTM
FERDICAIRAALTPKSCSLPLPLPPKKRAPTQVQTCVWDVSSPFKIVLVNASKVNAEETA
KVQVRAGLFHGTELLCKPAVSSESSGRSDHAWKDTTLEFELPVCDLPRMTRLCFAIYAVM
DKVKKQKSTKNTHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDE
LEEMLNPIGTIQTNPYTENATALHISFPEYSSHPIIFPLFDKILEKAAEIAGASDCASMG
RGGKKFHIELKEIMERDALSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDM
AQLQALLQIWPRLCPRDALELLDFNYPDQYVREYAVNCLRDMSNDELSQYLLQLVQVLRY
EPYYDCALTHFLLERAQSSRKIGHFLFWHLRSEIHMPAVSVQFSLILEAYCRGSIPHIEV
LKKQVEALNKLKAVNELIKLGTLKNARSKTKEAMLTKEAMMTCLRQTGFSETLSDLHSPL
NPNILLSGINVEKCRYMDSKMKPLWIVYNNKLLVGDMLGIIFKNGDDLRQDMLTLQILRL
MDRLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNMAAAAAFNKDALL
NWIKERNSGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSNGQLFHIDFGHIL
GNFKSKFGIKRERVPFILTHDFIHVIQQGKTGQAEKFGSFRQYCEKAYLILRKNGNLFIT
LFALMLTAGLPELTSVKDIQYLKDSLALGKSDDEALKQFRQKFDEALRESWTTKVNWMAH
NVAKDNRS
>A0A4Z2B899|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu bimaculatus|TrEMBL
MPPGKYGMQEEWEKEGDQRIVMDFLLPTGIFLKFPVSRNDTIRTIKKMVWKNAQSEALYA
ALGDPDSYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVARVGDRVEKLTNTQISQL
TGKGLHEFEAQKNHEVDEFRAKMRTFCEEKAQERQVLPWLQWMECNFPCELEPCSSPVEC
GGVKSKNTKIFINVKFEASDESFMLQQDPQDLPAALMRAALKKKATVFRSVRQEPEDYTL
QVNGRWEYIYGRHPLSQFKYIFSCLRNSQNPHLTMVHHSTIRKYQEEQGRACSQAYKCHR
PSRPPPLPLKKQNTSSLWSINEPFHIRLLHGSRVNAAEGMKLVVQAGLFHGSELLCKMVT
STEVAVCSEPVWDQKLEFDINFSDLPRMSRLCFALYAVIEKNKKPRGTKKKNKKADCPIA
WVNTMVFDYKDQLKTGEFLLSTWPVYDKGDLLNPMGTVEKNPNVDSAAGLLIQFPNVRPH
PLYYPPLEKISDLEKNGFAVVATKVEHIKLKEIMDNKNYTEIFEDEKELLWKLRSVVCDH
YPESLSKLLLITNDEELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNSRIGHFLFWHL
KSEIHVPSVSLRFSLILEAYCRGNIWHIKLLIKQNEALLKMKTLSDIVKSGSQKMTVDDL
KLCIKQESYLETLSDLLSPLNPSVVLAEICADKCRFMDSKMKPLWLMYKSPWAQGDMMGI
IFKNGDDLRQDMLTLQMIRLMEILWKKEGLDLRMIPYSCLSTGNKMGLIEVVKNSDTIAN
IQRNSSNSAATAAFNKDALLNWLKSKNPEGRLEKAIEEFTLSCAGYCVATYVLGIGDRHN
DNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERF
REYCERAYKILCRNGMLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEEEALKNFK
VKFNEALRESWKTKLRRLEGCDPGTGRLPSATHHSNGAQKKENLDQEGATGEAGMNREEA
PGKSPEDMYIQQKVRVLLMLKKMGSNLTPSEEAFLRNYAGVVHSQMSQLPQHNIDQGAED
VVTAFSRSETEDRRQ
>A0A7K9V032|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Anseranas semipalmata|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSMQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQIAPDEFPITLMSYAIKKQATVFRHETMENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINCIANTPKMA
AKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKMVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKAGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPNVAS
HPVYYPSFEQLLELGRNGEQPRTAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVMISLLQTWPELPVLNALELLDFSFPDRYVGSFAINS
LKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPA
VALRFGLILEAYCRGSTHHIKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHMCM
KQETYLEALSHLQSPLNPSIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLN
KSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
EKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLKFN
EALRESWKTKVNWLAHNVSKDNRQ
>A0A1S3GTK1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dipodomys ordii|TrEMBL
MEFWTKEENQSVMVDFLLPTGVYLNFPVSRNANLSTIKQVLWHHAQYEPFFHMLSDPEAY
VFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVARECDHVKKLINSQISLLIGKGLHEF
DSLRDPEVNDFRDKMRQFCEEAVAHRQQLGWEAWLRYSFPLQLEPLARSLGAGTPKTPNQ
TMLVNVKFEGNEESFTFQVSSKDKPLALMACALRKKAKMFSQCLVEQPEDYALRVNGRHE
YLYGSYPLCQFQYICSCLHSGRTPHLTMVHSSSILTMRDEQSNPTPQVQKPCTKPPPIPA
KKPSLVSLWSLEKAFCIDLIQGSKVNADERMKLVVQAGLFHGNELLCKTVCSSEVSMCSE
PVWQQRLEFEINVCDLPRMTRLCIMLYAVVEKTKKARSTKKKSKKADCPIAWANLMLFDY
KNQLKTGECCLYMWPSVPGEKGELLNPVGTVCSNPNTKSASTLLICLPEVAPHPVYYPAL
EKILELGHHGERAHATEEELQLREILERQGSGELYEHEKDLVWKLRHKVQEHFPEALARL
LLVTKWNKHEDVAQMLYLLRSWPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTDDELS
QYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPSVALRFGLILE
AYCRGCTHHMKMLMKQGEALSKLKALNDFVKVSSQKMTKPQTKELMHLCMRQDTYMEALS
HLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEETGYAGNMGIIFKNGDDLRQDML
TLQMIQLMDILWKKEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNNSNMAATAA
FNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFH
IDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRR
HGLLFLHLFALMRAAGLPDLSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKT
KVNWMAHNVSKDNRQ
>A0A7L4BBE0|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phaetusa simplex|TrEMBL
MELGDYEQPVVMREENKRRRRRMKPHCTSSNLSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHTFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQSQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHEKVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGLSTKTNLQSHESPNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A2K6AN16|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Macaca nemestrina|TrEMBL
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEH
EPSIPENLEDKLYGGKLIVAIHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDE
VSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFVLVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKE
ILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGYWVIYKGKNDEELSQYLLQLVQVLKYEPFLDCALS
RFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALN
KLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCK
YMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRML
PYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRA
IEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVP
FILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTS
VKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A1S3GQG9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Dipodomys ordii|TrEMBL
MELEHHDQPVVLREDNHRRRRRMKPRGAAASLSSMELIPIEFVLPTSQRHSKTPETALLH
VAGRGTVAQMKAQLWLRALETSVAADFYHRLGPDRFLLLYQKKGQWYEIYDKCQVVQTLD
CLCHWKGLRRSPGQIHVVPRHAPSEETLAFQRQLTALIGYDVTDVTNVHDDELEFTRRRL
LTPRMAEVAGRDARLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSADDT
PGCILRSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKMG
EEIHLVLDTPPDPARDQVREEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRR
FRVKIRGIDIPVLPRNAELTVFVEANIQHGQQVLCQQRTSPKPFTEEVLWNAWLEFRIRI
KDLPRGALLNLQLYCGKAPALSAKAESPGAESRGRVQLLYYVNLLLIDHRGLLRHGEYVL
HMWQISAKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHCPTPDPEGDR
VRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQE
MVAKTYQLLTRKEIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLEGLEDDDVLHYLLQ
LVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLR
GCGTAMLQDFTQQVQVIEMLQKVTIDIKSLSADKYDVSSQVISQLKQKLENLQNSNLPQS
FRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDM
LILQILRIMESIWETESLDLSLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAF
KDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFH
IDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQGSFSSRQTHHY
>A0A674NYU2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMLKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKEYQGQYILKVCGCDEYLLEKYPLSQYKYIR
SCIIVGRLPHLMLVSKDSLYSQLPASGFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNT
PLRVRLLCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIY
LADLPRSARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYKDILVSGKVALSLWPVPHGL
EDLLNPIGVAGSNPNKETPCVELEFSWFNQTVVFPDEQQIEEHANWTISRELGYNYCHGL
MYCLLKEWSLMEPELALELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYE
MYLDNPLARFLIKKSLTNQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHL
NRQVEAMDKLVNLTDTLKQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLG
NLRLEECRIMSSAKRPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMEN
IWQNQGLDLRMLPYGCLSIGDCVGLIEVVKNSFTIMQIQCKGGLKGALQFNSNTLHHWLK
DKNRGEAYDRAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKK
KKFGYKRERVPFVLTQDFLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLF
SLLLGCGMPELQSFDDIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTI
RHMPNEH
>H2TLW7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
LLLNVNVLVSMPTGLPLQPVWCSRMVWKNAQSEALYAALGDPDSYVFTCINQTAEREELE
EESRRISDVRPFMCVLRLVARVGDRVEKLTNTQISQLTGKGLHEFEAQKNHEVDEFRAKM
RTFCEEKAQERQVLPWLQWMECNFPCELEPCSSPVECGGVKSKNTKIFINVKFEASDVSL
FMLQQDPQDLPAALMRAALKKKATVFRSVRQEPEDYTLQVNGRWEYIYGRHPLSQFKYIF
SCLRNSQNPHLTMVHHSTIRKYQEEQGRACSQAYKCHRPSRPPPLPLKKVRVVNPTFNCF
PIQLVVQAGLFHGSELLCKMVTSTEVAVCSEPVWDQKLEFDINFSDLPRMSRLCFALYAV
IEKNKKPRGTKKKNKKAVGDCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPGDLLNPMGT
VEKNPNVDSAAGLLIQFPNVRPHPLYYPPLEKHIKLKEIMDNKNYTEIFEDEKELLWKLR
SVVCDHYPESLSKLLLITKWNKREDVVQMVGLLRYWSDLPAIHALELLDYSFPDPAVRAF
TIRCLRKLSDEELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNSRIGHFLFWHLKSEI
HVPSVSLRFSLILEAYCRGNIWHIKLLIKQNEALLKMKTLSDIVKSGSQKMTVDDLKLCI
KQESYLETLSDLLSPLNPSVVLAEICADKCRFMDSKMKPLWLMYKSPWAQGDMMGIIFKN
GDDLRQDMLTLQMIRLMEILWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRN
SSNSAATAAFNKDALLNWLKSKNPEGKLEKAIEEFTLSCAGYCVATYVLGIGDRHNDNIM
IRETGQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYC
ERAYKILCRNGMLFVNLFAMMKAAGLPELTSSKDIQYLKDSLALGKSEEEALKNFKVKFN
EALRESWKTKVNWMMHSLAKDNRP
>A0A674N9W1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Takifugu rubripes|TrEMBL
MPPGKYGMQEEWEKEGDQRIVMDFLLPTGIFLKFPVSRNDTIRTIKKMVWKNAQSEALYA
ALGDPDSYVFTCINQTAEREELEEESRRISDVRPFMCVLRLVARVGDRVEKLTNTQISQL
TGKGLHEFEAQKNHEVDEFRAKMRTFCEEKAQERQVLPWLQWMECNFPCELEPCSSPVEC
GGVKSKNTKIFINVKFEASDESFMLQQDPQDLPAALMRAALKKKATVFRSVRQEPEDYTL
QVNGRWEYIYGRHPLSQFKVSGHEKPPPLPLKKNTSSLWSINEPFHIRLLHGSRVNAAEG
MKLVVQAGLFHGSELLCKMVTSTEVAVCSEPVWDQKLEFDINFSDLPRMSRLCFALYAVI
EKNKKPRGTKKKNKKADCPIAWVNTMVFDYKDQLKTGEFLLSTWPSVPDDKGDLLNPMGT
VEKNPNVDSAAGLLIQFPNVRPHPLYYPPLEKVPVHFYIICRCRNSPVCSCLPMSLCSLQ
HIKLKEIMDNKNYTEIFEDEKELLWKLRSVVCDHYPESLSKLLLITKWNKREDVVQMVGL
LRYWSDLPAIHALELLDYSFPDPAVRAFTIRCLRKLSDEELLQYLIQLVQVLKYESYLDC
DLTTFLLERALSNSRIGHFLFWHLKSEIHVPSVSLRFSLILEAYCRGNIWHIKLLIKQNE
ALLKMKTLSDIVKSGSQKMTVDDLKLCIKQESYLETLSDLLSPLNPSVVLAEICADKCRF
MDSKMKPLWLMYKSPWAQGDMMGIIFKNGDDLRQDMLTLQMIRLMEILWKKEGLDLRMIP
YGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSAATAAFNKDALLNWLKSKNPEGKLEKAI
EEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFLGNFKRKLGINRERVPF
ILTYDFVHVIQQGRTNNSEKFERFREYCERAYKILCRNGMLFVNLFAMMKAAGLPELTSS
KDIQYLKDSLALGKSEEEALKNFKVKFNEALRESWKTKVNWMMHSLAKDNRP
>A0A8J6KBC3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eleutherodactylus coqui|TrEMBL
MPPGVYCPVDFWAKEEKQSISVDFLLPSGIYLNFSVPCSASLGNIKKILWQRAQQEPLFH
TLGSPTSYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAEKLLNSQISLL
IGKGLHEFDSLNDPEVNDFRSKMRQHCEESALQRQHMNWDSWMESNFPLRLEHFSKAFTK
TSQSNKTLMINVKFEGSEESFTLQVSPRDFPLSLIRMALRKKSNVSGQQCPGRPDDYILQ
VNGVLEYIYGNYPLCQFTHINHCLRFSCTAHLTLVTIASTLPDQQGDAIVSSKIRHKPPP
LPTKKPHHCSLWKLERPFCFQLLYGYNVNADDGLKLLVHCGLYHGSELLCKTVASSEVNA
SSDPQWFQLLDFDINTCDLPRMTRLSLALYAVDKSKKAKSTKKKSKKTDYPIAWVNTMLF
DYKDMLKCGEYSLCMWSSFPDEKGEMLNPMGTVHCNPNTESAATLSICFVNVSDYPVYYP
SIEKILELGRLGEVSNATPDERQQLLEIVERKGQAELYEHEKELVWKLRHEIKERHPEAL
PKLLLTTKWNKHEDVAQMVYLLQTWPELPVLTALELLDFNFPDRHVGSFTMSCLKKLTNE
ELCQYLLQLVQVLKYESYLDCELTMFLLDRALIHRKIGHFLFWHLRSEMHVPAVALRFGL
ILEAYCRGSIYHMKVLMKQGEALSKLKGLNDFVRSSVQKTSKAQAKEAMHMCMRQDTYLE
PLSHIYSPLDPNLILTDVCVELCTFMESKMKPLWIVYNNDMLGGSRVGIIFKNGDDLRQD
MLTLQMIKLMDVLWKKEGLDLRVTPYGCLSTGDKTGLIEVVMHSDTIANIQRNKSNMAAT
AAFNKDALLNWLKSKNPGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQL
FHIDFGHFLGNFKTKFGFNRERVPFILTYDFVHVIQQGKTNNSEKFERFRDYCEKAYTIL
RCHGALFLNLFALMKAAGLPELTCSKDIQYLKDSLALGKSDEDALKQFQVKFNEALRESW
KTKVNWFAHTVSKDNRQ
>A0A8J6KHI4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eleutherodactylus coqui|TrEMBL
MPPRPSSGELWGIHLMPPRILVDCLLPNGMMVTLECLREATLVNIKHELFKEARKYPLHH
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRKNILNVCKDAVELRDANGPISRALYVYPPNVESSSELPKH
IESKLDKGQIIVVIWVIVSPNNEKQKYSLKINHDCVPEHVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKDSLYNQIPVD
TFTMPSYSRRISTATPYMNGEASAKSLWAINSNLRIKILCATYVNVNIRDIDKIYVRTGI
YHGVEPLCDNVNTQRVPCSNPRWNEWLLYDMFIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDCF
SSPVKFPDMVAIEDHANKVLEREMGYNYSHSGLTSRIARDNEVRESDKEQLKAISTRDPL
SEITEQEKEFLWSHRLYCRNTPEILPKLLLAVKWNCRDDVAQMYCLLKDWPPIRPEQAME
LLDFNYPDRIVRSFAVTCLEKYLTDDKLSQFLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDEPHKVQMKFLVEQMKRPDFMDALQGFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSEMLFLNNEIIFKNGDDLRQDMLTLQILRIMESIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRCSHTIMQIQCKGGLKGALQFNSHTLHQWLRDKNKGETYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDNGQVREDLVFVVFLFVFLVCFLVHVQRRIVYGHVC
VWFSMRT
>A0A8C5FTJ9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
ILLKQLVWRRASSEPLFNALGDPASYVFVCISSAAERLELEAEHRRLADVRPFACFLQLV
AREGDRAEKLANAQISLLIGKGINEFEAQKNHEVSEFRARLRAFCEEKALQQQALPWFQW
MECNFPCDLEPCRALPSRGGGAKAPKKIFINIQFEGSDVSPFMLQQDPQEPPLALIRSAL
KKKATVFRWVRQEAEDYTLRVNGRWDFLYGDHPMCQFKVTPDLYPPPTPPLRHLCTSLMK
AYQNTTLLWTISEPLCIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKLVTSSEVAVGSD
PVWNQRLEFDINVADLPRMSRLCIALYAVVEKAKKPRGTKKKSKRADCPIAWVNTMVFDY
KDQLKTGEFLLSMWPSIPDDKSELLNPMGTVEKNTNVDSAAALLIHFPSVRPQPLYYPPH
DKVTGGGGSRAPHRSSVDLLKEIMDNKNHTEFFEDEKELLWKLRGAVQSLYPESLSKLLV
ITKWNKREDVAQMVGLLRAWPELSGLHALELLDYSFPDPSVRAFTVKCLKKLGDRELMQY
LIQLVQVLKYESYLDCDLTSFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILEAY
CRGNIHHIRSLTKQNEALGKLKALSDIVKSGSQKMSADDLKLCIKQDSYMEALSDLLSPL
NPSIILSEICVEKCKYMDSKMKPLWLMYKNQWVPGDLMGIIFKNGDDLRQDMLTLQMIQL
MENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRDNSNSAATAAFNKDALL
NWLKSKNPEHKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGHFL
GNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRDYCERAYKILCRNGTLFVN
LFAMMKAAGLPELSSFKDIQYLKDSLALGKTEEEALKSFKVKFNEALRESWKTKVNWMMH
SLAKDKRP
>A0A8C5AL79|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Gadus morhua|TrEMBL
MPPGNYGMEEEWEAEGNADIMVDFLLPTGIFLEFPVSRNDTIADIKKLVWRRASSEPLFN
ALGDPASYVFVCISSAAERLELEAEHRRLADVRPFACFLQLVAREGDRAEKLANAQISLL
IGKGINEFEAQKNHEVSEFRARLRAFCEEKALQQQALPWFQWMECNFPCDLEPCRALPSR
GGGAKAPKKIFINIQFEGSDESFMLQQDPQEPPLALIRSALKKKATVFRWVRQEAEDYTL
RVNGRWDFLYGDHPMCQFKYIFSCLRDGQNPQLTMVYHSTIRAYQEDQGSAWRQGSKSST
SASKPPPLPLKKVGPEAHVSEPLCIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKLVTS
SEVAVGSDPVWNQRLEFDINVADLPRMSRLCIALYAVVEKAKKPRGTKKKSKRADCPIAW
VNTMVFDYKDQLKTGEFLLSMWPSIPDDKSELLNPMGTVEKNTNVDSAAALLIHFPSVRP
QPLYYPPHDKVTGGGGSRHVRLKEIMDNKNHTEFFEDEKELLWKLRGAVQSLYPESLSKL
LVITKWNKREDVAQMVGLLRAWPELSGLHALELLDYSFPDPSVRAFTVKCLKKLGDRELM
QYLIQLVQVLKYESYLDCDLTSFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFGLILE
AYCRGNIHHIRSLTKQNEALGKLKALSDIVKSGSQKMSADDLKLCIKQDSYMEALSDLLS
PLNPSIILSEICVEKCKYMDSKMKPLWLMYKNQWVPGDLMGIIFKNGDDLRQDMLTLQMI
QLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRDNSNSAATAAFNKDA
LLNWLKSKNPEHKLEQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETGQLFHIDFGH
FLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFRDYCERAYKILCRNGTLF
VNLFAMMKAAGLPELSSFKDIQYLKDSLALGKTEEEALKSFKVKFNEALRESWKTKVNWM
MHSLAKDKRP
>A0A8C1J8P1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPGVYGMQDVWEREDRQQITMEFLLPTGIYLNFPVACSDTISTIKKMVWKNARNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRLFLPILRLVAREGDRVEKLITTQISLL
IGKGHHEFESQKNHEVNEFRTKMRIFCEEHAQVRQMLPWEPWMEFNFPCDLEPCCVVAQS
GKSRSVKKILVNVKFEGSEETFVLQQDPQDLPMLLKRNALRKKSTVFRAAKQEKPEDYTL
QVNGRWEFIYGEYPLCQFKYIFTCLHGGITPHLTMVHHSVIIKYQEEQGGLSNQMSRTRA
PSKPPPLPLKRQNTSSLWSIHEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVI
SNEVSVCSEPVWDQKLVFDIGVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGMNGEKVVTTKEEHMKLREIVDNKNYTEFFEDEKELLWKLREEVRQ
RYPESLPKLLLITKWNKHEDVAQMVGLLRKWPELPAIHALELLDYSFPDPHVRSFTIRCL
RNLRDDELFQYLLQLVQVLKYESYLDCDLTCFLLKRALANKKIGHFLFWHLRSEMHVPSV
SLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSGSQKATRIQTTEDMKVCIK
QDTYMEALSDVVSPLNPSIVLCELCTDKCKFMDSKMKPLWLMYKNKYDHVGIIFKNGDDL
RQDMLTLQMIQLMDVLWKTEGLDLRMLPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNS
AATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRET
GQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRECCEQAY
KILCRNGTLFVNLFALMKAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKVNWMMHTFAKDNR
>A0A669QWI5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phasianus colchicus|TrEMBL
MQWNIIWFLSRMPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVV
WKHAQYEPLYHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRV
KKLINSQISLLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPL
QLEPMAKGLGTGLLHTPTKNIFVNVKFQSGGVNFTFQISPNEFPITLMSYAVKKQATVFR
HETMENPEDYTLQVNGKYEYLYGNYPLYQFQVSLLSCFDKRKSPNYGSLWSLEQSFYIEL
VQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLDFDINICDLPRM
ARLCFALYAVIEKAKKARSTKKKSKKAVSKDCPIAWVNVMLFDYKDQLKTGECCLHMWSS
FPDEKGELLNPMGTVQCNPNTESAAALLICFPNVASHPVYYPSFEQVGNTDVFLRGESLA
SLQLKEILERRSHTELYEHEKDLVWKMRHDIRDQYPQALAKLLTITKWNKHEDVAQMISL
LQSWPELPVLNALELLDFSFPDRYVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDC
ELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGE
ALSKMKALNEFVKLSSPKATKPQAKEMMHVCMKQETYLEALSHLQSPLNPSIILTEVCVD
QCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDL
RMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGDAL
EQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRE
RVPFILTYDFVHVIQQGKTNNSEKFERFRGYCEKAYMILRRHGPLFLHLFALMKAAGLPE
LSCSKDIQYLKDSLALGKTDEEALKHFRLKFNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C2G248|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cyprinus carpio|TrEMBL
MPPAKTDQLDLWVESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQNIKLLLWKEAQTYP
LFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERILDSKI
GVLIGKGLHELDALQDQEVKDFRSKMKRISEEKMQCMQLMSWGEWLRSCYSMTLEAGSLE
NLIDKHEGVIKITMHYDQSQDTSSLKVSLHCTVTELMDLALKKWQTTHVPEEDIGFRSDY
VLRVSRKLEFLFEDHHLNQCKYIRDCLLTNESPHLTLVHCDVVKAMFEKEISTIGSVLAW
KTSNPPLPLPPKKRLPTASTLFPALQLIKGVLSFIQVRAGLFHGTELLCKTAVSSESSSR
SEHVWNKTLEFDIAVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHY
PIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFP
EYSTQPVVFPAFDKILEKAAEIAGASDSMTMGRGGKKFYIELKEIMERDPLSQLCENEKD
LIWTLRHDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPD
QYVREFAVNCLRDMSDDELLQYLLQLVQVLRYEPYYDCALSRFLLERAQSSRKIGHFLFW
HLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALSKLKAVNELIKFGTIKTKTK
QAHLKEAMMTYLCVCRCKYMDSKMKPLWIVYNNKLLGGDTVDIIFKNGDDLRQDMLTLQI
LRLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKD
ALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFG
HILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTSNTEKFGNFRQYCEEAYLILRKNGNL
FITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNW
MAHIVAHPS
>A0A669R1W7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Phasianus colchicus|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GLLHTPTKNIFVNVKFQSGGESFTFQISPNEFPITLMSYAVKKQATVFRHETMENPEDYT
LQVNGKYEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQINSIANPPKMA
VKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALLICFPNVAS
HPVYYPSFEQLLELGRNGEQPRSMISLLQSWPELPVLNALELLDFSFPDRYVGSFAINSL
KKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHVPAV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKMKALNEFVKLSSPKATKPQAKEMMHVCMK
QETYLEALSHLQSPLNPSIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIFKNG
DDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQLNK
SNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMI
RETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCE
KAYMILRRHGPLFLHLFALMKAAGLPELSCSKDIQYLKVRKAEPGCG
>A0A8D0F761|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Strix occidentalis caurina|TrEMBL
MPPGIYCPMEFWSKGENQNIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGLGT
GPLHNPTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPEDYT
LQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCIAGPPKLA
AKPPPLPKKKPNYGSLWSLERSFYVELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAS
HPVYYPSFEQLLELGRNGEQTRAAPEDPEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKSSSQKAPKPQTKEMMHV
CMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMAATAAFNKDALLNWLKSKNPGDALEQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A2K6SFZ8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Saimiri boliviensis boliviensis|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRSAAASLSPMELIPIEFVLPTSQRNCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRAPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVAGRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKYLMDIPESQSERDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKAPAESPSSESKGKAQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCYPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVIAQLKQKLENLQNSHLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSKETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A7K8B3U4|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cnemophilus loriae|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLSVPCNASLDTIKQVLWKHAQYEPLFH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQISLL
IGKGLHEFDSVQDPEVSDFRTKMCQFCEEKAAKRQQLSWAAWMEYNFPLQLEPMAKGLGA
GSLQIPTKNIFVNIKFQSGGESFTFQISPWEFPITLMSYAIKKQATVFRPETVQKPEDYT
LQVNGKCEYLYGNYPLYQFQHIRSCLQRGRTPHLTMVHSSAIIAMRDEQTNCIASPPKAA
SKPPPLPKKKPNYGSLWSLEQPFSIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKMGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAA
HPVYYPSFEQLLELGRNGEQPRAAPEDSEEKLQLKEILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDDDVFQYLLQLVQVLKYESYLDCELTKFLLERALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHM
CMKQETYREALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMVRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNIEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A8C9WYQ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Sander lucioperca|TrEMBL
MPPGKYGMQEEGDQEIMMDFLLPTGIFLKFPVSPNDTIKSIKKMVWKNARSEALFSALGD
PDAYVFTCINQTAEREELEEESRRISDVRPFMGVLRLVAREGDRVEKLTNTQISLLIGKG
LHEFEAQKNHEVNEFRAKMRTFCEEKAQERQMLPWQQWMEYSFPCDLEPCCSPPECGSVK
SKNTKKIFINVKFEACDESFMLQQDPQDFPVALMKSALKKKATVFRSVRQEPEDYTLQVN
GRWEFIYGNHPMCQFKYMFLCLRNSQIPHLTMVHHTTISKYQEEQGRMCSQGYKTRSLSR
PPPLPLKKNTSSLWSINEPFYIHLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVTTSEV
TVCSEPLWDQKLEFDINVADLPRMSRLCFALYAVIEKAKKPRGTKKKNKKADCPIAWVNT
MVFDYKDQLKTGEFLLSTWPSVPDDKSDLLNPMGTVEKNPNVDSAAGLLIRFPNIRPHPL
YYPPLDKVRILKRGKTFYISHFTSLTQLKRMKLKEIMDNKNHTEFFEDEKDLLWKLRTEV
RDHYHESLSKLLLITKWNRREDAVQMMSLLRTWRDLPAIHALELLDYSFPDPVVRSFTIR
CLRKLSDDELLQYLIQLVQVLKYESYLDCDLTTFLLERALSNWRIGHFLFWHLRSEIHVA
SVSLRFGLILEAYCRGNIHHIKLLSKQNEALGKMKALSDFVKSGSQKMTADDLKLCIRQE
SYLEALSDLLSPLNPSIILTEICADKCRFMDSKMKPIWLMYNPCTQEDMVGIIFKNGDDL
RQDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNS
AATAAFNKDALLNWLKSKNPEDKLDRAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRET
GQLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAY
KILCRNGMLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKVNWMMHSLAKDNRP
>M3Z0I7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mustela putorius furo|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>M3Z3H5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mustela putorius furo|TrEMBL
MELENYEQPVVLREDNRRRRRRMKPRNSAASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSEETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFAKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIRNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPRGALLNLQIYCSKTPVLSGKVAAESPSSESKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDHGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVHVIETLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNANLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSSETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>H3B6T5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Latimeria chalumnae|TrEMBL
KMPPRPSSGELWGIHLMPPKILVDCLLPNGMIVTLECLREATLVNIKRELFKEARKYPLH
QLLQDESSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGF
AIGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDVNGSHSRALYVYPPNVESSPELPK
HIFSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQL
KMCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLSRMPNLMLMTKESLYSQLPV
DTFTMPSYSRRISTATPYMNGEASAKSLWILSGPLRIKILCATYVNVNIRDIDKIYVRTG
IFHGGEPLCDNVNTQRVPCSNPRWNEWLKYDIFIHDLPRAARLCLSICSVKGRKGAKEEH
CPLAWGNINLFDYTDTLVSGKMALNLWPVPHGMEDLLNPIGGTGSNPNKETPCLELEFEW
FSSPVKFPDMSAIEDHANRAVSRELGLNYFQAGVSSRTARDSGLTDGDKEQLRAVGNRDP
LSEITEQEKDFLWRNRQFCVNLPEVLPKLLLSVKWNSRDDLAQMYCLLKDWPPIKPEQAM
ELLDCNYPDPMVRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALT
NQRIGHFFFWHLKSEMHNKTVTQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDIL
KQEKKDETQKVQMKFLVEQMRRPDYMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGDVFKREKYLHLCIVVVVNSLQSYNLFSRMLPYGCL
SIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHALHQWLKDKNKGEMYDAAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGAQECTKTREFERFQETCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
>A0A3P8RBR2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Astatotilapia calliptera|TrEMBL
MPPGKYGMQEEWEKEGDQAINMDFLLPTGIFLKFPVSRNDTIKSIKKMVWKNARSEALFC
GLGDPDGYVFTCINETAEREELEEESRRISDVRPFMCVLRLVAREGDRVEKLTNAQISLL
IGKGLHEFEAQKNDEVNEFRTKMRAFCEEKAQDRQSLPWQKWMEYSFPCELEPCCSLPQS
LKTKNIKKIFINVKFEASDESFMLQQDPHDLPLVLMKSALKKKATVFRLMRQEPEDYTLQ
VNGRWDFIYGKHPLCQFKYIFSCLRNGQNPHLTMVHYSTVTKCQEEQGRMCNQVYKSRSL
SRPPPLPLKKQNTSSLWSINEPFHIHLVQGKRVNADEGMKLVVQAGLFHGSELLCKVVTS
SEVTVSSEPLWNQKLEFDINVADLPRMSRLCFALYGVIEKTKKPRGTKKKNKKADCPIAW
VNTMVFDYKDQLKTGEFHLSTWPCVPDEKSDLLNPMGTVEKNPNVDSAAELLIHFPNIRP
HPLYYPPLEKICDMERNGDLSLATKDEYFKLKEFMDNKNYTEFFEDEKELLWKLRTEVRD
HYPESLSKLLLITKWNKREDVVQMVNLLRNWPDLPAIHALELLDYSFPDPAVRSFTIRCL
RKLSDDELLHYLIQLVQVLKYESYLDCDLTTFLLERALSNRRIGHFLFWHLRSETHVASV
GLRFGLILEAYCRGNIHHIKLLTKQNEALGKMKALSDFVKLGSQKVTAEDLKQCIRQESY
LEALSDLLSPLNPSIILSEICTDRCRFMDSKMKPLWLMFKNPAVEGDMVGIIFKNGDDLR
QDMLTLQMIQLMENLWKKEGLDLRMIPYGCLSTGNKMGLIEVVKNSDTIANIQRNSSNSA
ATAAFNKDALLNWLKSKNPEDKLDQAIEEFTLSCAGYCVATYVLGIGDRHNDNIMIRETG
QLFHIDFGHFLGNFKRKLGINRERVPFILTYDFVHVIQQGRTNNSEKFERFREYCERAYK
ILCRNGTLFVNLFAMMKAAGLPELTSFKDIQYLKDSLALGKTEDEALKNFKVKFNEALRE
SWKTKVNWMMHSLAKDNRP
>A0A6J2REF7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Cottoperca gobio|TrEMBL
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSVELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGMEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMTIIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPTIKPEQAME
LLDCNFPDPMIRDFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
>A0A091QR83|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Mesitornis unicolor|TrEMBL
SRMPPGIYCPMEFWSKGENQIIQVDFLLPTGIYLNLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVQDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPMAKGL
GTGPLHTSTKNIFVNVKFQSGGESFTFQISPKEFPITLMSYAIKKQATVFRHETLENPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLMPHLTMVHSSTIIAMRDEQTNCIASPPK
MAAKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDDKGELLNPMGTVQCNPNTESAAALVICFPSV
ASHPVYYPSFEQVGDMGAFLREAKNLVYALSSDSHKQKLQLKEILERRSHTELYEHEKDL
VWKMRYDIRDQYPQALAKLLIITKWNKHEDVAQMISLLQSWPELPVLNALELLDFSFPDR
YVGSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWH
LRSEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKVLNDLVKVSSQKATKPQ
TKEMMHVCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGG
GGVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHS
DTIANIQLNKSNMVATAAFNKDALLNWLKSKNPGDALEQAIEEFALSCAGYCVATYVLGI
GDRHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNE
KFERFRGYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEA
LKHFRLKFNEALRESWKTKVNWLAHNVSKDNR
>A0A7L1A3M8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Oxyruncus cristatus|TrEMBL
MELGNHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPALPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNVWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNPDTKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>B0E5N8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Entamoeba dispar (strain ATCC PRA-260 / SAW760)|TrEMBL
MDSYWLPPVSSNSLPVKTKPRSNTIQLSTFNNPTRQKKVVPLVSKTESKFFHSSSATVLE
KKTITQSETKVNPSTRRPLPSLPPNYSQQPIGIAKKTNNQQTSSDEINLRVLSVKQPNDL
PNQLEFMLSKQRTILGIDDKRKKPIKTSKMAKTLKPINSSEHTQTSEIPYEESRLAKRKV
SVLSDQEKKAISLLANGISGLGKSGIHGNNNDIVEREYLCINQSTKPILISKDMMNVEDT
VEIRNFLQISELALHQMNGEVLPYNYIEAETSCGGLTQPVILTINTSFSQYKISFKCMTN
LKWVEIKKMIEKGINTKASTRLPIKISNHKLVIAGTRLYFQEQKEMREYSIINDISRREK
IINIELINQIQFKEEINQIQLKHQNLLLKEKKKCKASNFSDEILSFTIYELLNFDPEIVF
KKFFDESEITNCIKNYFETRSFEKYKIILKVSCCLYMGTDKLCNKEYFTSDVINTIFDCK
IMTDFSYSMLPLETRLGITLYAIRKGKKVVIGFVNTPLFDFQNFLLSGYVNLKLWPDEES
DAVSSPLQNPSSTAPIISIKFPDPVIKIFYQPYEAKYPQIPKNLLKISNDVQQLALHNDP
FQPLTNEQKNEIWQNRFNILIQFPDSIDLLLRAVPWTDYKAREEMADLIKIWPGISPIQV
IGLLDVRNSFTPARDYAVRLLEETNDKVILGYLPQFIQVLKFESYTCSSLALFLLKRALK
NRGDMGQLFYWLLVGENEKTKISLRSKILLEVYNSMCGIQLKELKTQENFIKIIEETAVN
AKHWKDDEVKTNLPNMLTVVNNALEGSRLTLPFTSRETVSCVVINKCKVFDSNAHPILLC
FQSSPIFSQQETRFIFKVGDNLMQDMLTLQMFKLMDDLWKKNGIDFRMTIYNVLATSTTS
GIIQFVPNCETVNSIQTKGRGITGVFDDACIYEWIKSKNLEEEDLKNAIENFTYSCAGYC
VATYVIGVGDRHNDNIMVSKDGHLFHIDFGHFLGNIIKLGFYNKESAPFVLTNDFMFVIT
MGNTDTDNYSFFENICTKGFMILRNNAKTFIYSFMMMLCSGVPQLKHVEDVQYLKDAFML
DKTDDEAEQEFRSLISQSLGTFRTRLNFFMHSMVH
>A0A4W3GMC8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MPPRPSSGELWGLHLMPPRILVDCLLPNGMIVTLECLREATLVSVKHDLFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDHEVQDFRRNILSVCKEAVELRDVNGANSRALYVYPSNVESSPELPKH
ISNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCMPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQSKYILKVCGCDEYLLEKYPLSQYKYVKSCIILGRMPNLMLMTKDSLYTQLPLD
TFTIPSYARRISTATPYMNGEASAKFLWAINSVLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGDPLCDNVNTQRVPCSNPRWNEWLTYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTDTLVSSKMALNLWPVPHGMEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPSMSMIEDHANWTMSRELGYNYCLVGLSNRIACDSNLTEGDIEQLRSIGSRDPL
SEITEQEKDFLWRHRHYSVNVPEILPKLLLSVKWNSRDEVAQMYCLLKDWPPIKPEQAME
LLDCNYPDPMVRDFAVKCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQGFMSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQIQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEGYDGAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERTNVIC
>A0A4W3GZ53|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Callorhinchus milii|TrEMBL
MESTNPFYEIDPGMENKTNIEKNDELPIVMREENKRRRRNMRANTTRGMQYYSLEQLSIE
IILPTRNKRTAMHEKISLDIAGNYTVEQLKTKIWVKANGTSGSPEYYQKFSPDQFILLYQ
KKGQWYEIYDKQQVIQTLDCINYWKVLQKSVGKIHVVQKARSSDQSLQLQWDLNNLVGYD
VTDVSNVHDDELEFTRRTLITPRLTEVATRDVRLYSMDPWILSKPLPEYLLNKISGNNIF
MIIHRGAVSLTIKVSIDETPESILRNFFKKMAKKMSLLDMNESHSEEHFVLRVCGRDEYI
VGDNPIKDFFWIRNCLKNGEEIHLVLDLPPDPVLDEVQKEEWPLVDDCTGVTGSHEQLTL
EGKDHEKVFTISLWDCSQTFRVKIVGIDIPVLPRNTDVTVFVQASILHGQQILAQQRTPA
KAFTEEVMWNMWLEFDIKVKDLPKGARLNLQVYCGKAQALGSKALEDLWDSRSKNNMLYY
VNLLVIDHRSLLRQGEYLLHMWKIPNKGEEQGTIEADKLTSATNPDKQTSMAICILLDRY
NYPIALPRSRQTDPEAERSGPEMHSQLRKQFEEIVSTDPLNPLSAEDKELLWHFRHECVK
QPKAYPKFLSSVKWGQQDVVLKTHQLLQKQTAWASSPLDVGLALQLLDCRFSDEQVRTMA
VQKLETFGNDDVLRFLLQLVQAVKFEPYHDSALARFLLKRALGSKRIGHFLFWFLRSEVS
ESMHYRQRYAVMLECYLRGCGQAMLMDFMKQVKVIKELQKLTKEIKNVTADKYDISSQAI
SQLRHRLEKLQSSGFPECFRVPYDPGLRAGALVVDKCKVMASKKKPLWLEFKCADPTSVS
KDTIGIIFKQGDDLRQDMLIIQILLIMDSIWEMESLDLCLLPYGCIATGNKIGIIQIVKD
ATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCVIEEKFQSAVEKFVFSCAGYCVATYVLGI
GDRHNDNIMITESGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLFVMGTYGKKTSP
HFQKFQEICLKAYRTLRHHANLLIILFSMMLMTGMPQLTSKEDIEYIRETLTVGKNEEEA
RTHFLEQIEICRDKGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A674IDN8|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Terrapene carolina triunguis|TrEMBL
MELGNYEQPVVMREETKRRRRRMKPYSAASNLSSMELISIEFILPTSNKHTKVQETMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHKSTPDQFILQYQKKGQWYEIYDKHQVIQTLD
CILYWKVLQKKVGKIYVVQKQKPTEAVQEFQTQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYSMHPWITSKPLPEYVFKKITHNNIFIIIHRGTTSQKIKVSIDDT
PDMILQSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDDPPDPKEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIVGIDIPVLPRNTELTVFVEANIQHGQQLLSQRRTISKPFTEEVLWNTWVEFDIKI
KDLPKGALLNLQIYCGKAQALSTKVSLQSHDSPNSDSKCKTQLLYYVNILLIDHRSLLRS
GEYVLHMWKISGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRITSD
PQGDRTRAEMPNQLRKQLEAIVDTDPLNPLTPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKREAWDHSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQIIKLLHKVTMDIKSVSAEKYDVTSQVITQLKQKLEKLQNS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKDRCVIEEKFQAAVERFVYSCSGYCVATFVLGIGDRHNDNIMITES
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTAGKKTSLHFSKFQDICVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A6P8FG00|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Clupea harengus|TrEMBL
MGMQDVWEAEGQQVTVDFLLPTGIYLRLDVSRNDTISTIKKMLWRNAQSEPLYGALGDPD
AYVFTCINITAEREDLEDEQRRLGEVRPFLPILRLVAREGDRVEKLINAQISLLLGKGMH
EFEAQKNHEVNEFRTKMRTFCEERAQERQRLPWHEWMEYSFPCDLEPCPTMSHSGKLRNI
KKIFVNVKFEASEESFMLQVEPQDVPGTLIGKALRKKATVFRPSSKEKPEDYTLQIHGRW
EFVYGKYPLCQFKYIFSSLHGGQTPFLIMVHRSTISKYQEDQSCLSNQVSKGRSSSKPPP
LPLKKQNTSSLRSIQEPFYIQLLQGSRVNADEGMKLVVQAGLFHGSEVLCKVVTSSEVNV
CSEPVWDQKLVFDINVGDLPRMTRLCFALYAVVATTKKPRSTKKKSKRADCPLAWVNTMV
FDYKDQLKTGEASLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTACLFIRFPIIRPHPLCY
PPLDKISGLEINGEKAAATKEEHSKLKVIMDNKNYTEIFEDEKELLWKMRGEVRERYPDS
LSKLLLVTKWNKHEDVAQIVSLLRNWPDLPAIHALELLDYCFPDPHVRSFTIRCLRKLRD
DELFQYLLQLVQVLKYESYLDCDLARFLLERALSNKRIGHFLFWHLRSEMHVSSVSLRFG
LILEAYCRGSIYHMKSLVKQNEALNKMKALNDFVKSGSQKASRAQTTEDMKLCIKQDAYM
EALSDLLSPLKPSIILSEICADRCKFMDSKMKPLWLMYKNKWMQSDTVGLIFKNGDDLRQ
DMLTLQMIQLMDVLWKKEGLNLRMVPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNSAA
TAAFNKDALLNWLKSKNPGDKLDEAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQ
LFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQEGKTSNSEKFERFRDCCEQAYKI
LCRNGILFVNLFALMRAAGLPELSSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALRES
WKTKVNWMMHSFAKDNR
>A0A8C6UV34|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Neogobius melanostomus|TrEMBL
VCFRSLKTVLAKFCHLVIALARNASNMILLLWKQAQSFPLFPALGEMESHMFECVNQAAV
HEELEDETRRLCDVRPFLPVLKLITRNCGRAERLLDSKIGVLIGKGLHELDAINDQEVKD
FRGKTLRQSEEKMQKVQMMSCTEWLQASFSQQLEPGPGPDQINGVSDRSTDLKVTIHFDQ
SQDSASLKVPLSCTPPELMDMAVRKWLTTHGPEKEASRGQYFLRVSHSLEFLCGDDPLSH
YKVQVRAGLFHGESSGRSEHTWRDSTLEFEISVCDLPRMTRLCIAIYAVMDKVKKQKSTK
NTHINKYQTIRKSGKVLYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGT
VQTNPYTENATALHISFPEYLPHAIVFPPFDKILEKAAQIARASDCSPMGRGGKKFHIEL
KEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQVLLQIW
PKLSPRDALELLDFNYPDQYVREYAVGCLRDMSDEELSQYLLQLVQVLRYEPYYDCALTH
FLLERAQRNRKIGHFLFWHLRSELHMPAVSVQFSLILEAYCRGSIPHIEVLKKQVEALSK
LKSVNELIKFGTMKNARSKAKEAMLTKEAMMTCLRQSGYYETLSDIHSPLNPNILLAEVN
VERCRYMDSKMKPLWIVYNNKLLDGDTLGIIFKYGDDLRQDMLTLQILRLMDLLWKEANL
DLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNSGD
ALDHAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIK
RERVPFILTHDFIHVIQQGKTGYTEKFASFRQYCEEAYLILRRNGNLFITLFALMLTAGL
PELTSVKDIQYLKDSLALGKTDDEALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
>A0A7K4W7N2|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Tachuris rubrigastra|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKVPEMMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFVLQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQAHESSNSDTKCKSQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIASD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADSTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A091EDE5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Corvus brachyrhynchos|TrEMBL
DSIMPPAVTDSLDIWAVDSQIGADGSVSVDFLLPTGIYINLDVPRDATISQIKQLLWKQA
HSYPLFHLLMEIDSYMFSCVNQTAVHEELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLD
SKIGVLIGKGLHEFDALQDPEVNDFRAKMRRISEEKIQSLVGLSWMDWLKHTYPPEQEPV
IPESFQDKLYSGNLVVAVHFDNCQDVFSFQVSPNVNPIKLNELAIRKRLTIHGKDDEEVD
PADYVLQVSGRLEYVFGDHPLIQFQYIRNCVMNRTLPQLTLVECCTIKKMCEQEMIAIEA
AINRKSSNLPLPLPPKKTRATTSVWDISNPFKIILLKGNKLNTEENAKVHVRAGLFHGTE
LLCKTTVSTEISGRSDHVWNEVLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKAMNP
SKYQTIRKAGKVHYPVAWVNTMVFDYKGHLKNGELVLHSWSSFPDELEEMLNPMGTVQTN
PYTENATALHIRFQEYSKQPINYPPFDKILEKAAEIARNSDNAAMAGRGGKKFYVVLKDI
MERDPLSQLCENEMDLIWTLRYDCRENFPQSLPKLLLSLKWNKLEDVAQLQALLQIWPKL
LPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLL
ERALGNRRIGQMLFWHLRSEVHIPAVSVQFGLILEAYCRGSVAHMKVLAKQVEALNKMKT
LNSLIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELHVEKCRYMDS
KMKPLWIVYNNKMFGGDLVGIIFKNGDDLRQDMLTLQILRLMDVLWKEAGLDLRILPYGC
LATGDHSGLIEAVSSSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGEDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQYCEEAYLILRKHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
>A0A6P7Z895|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcaecilia unicolor|TrEMBL
MPPRPSSGELWGIHLMPPRIQVECLLPNGMMVGLECLREATLVTIKHELFKEARKYPLHH
LLQDESSYIFVSVTQEAELEEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDMVKDPEVQEFRRNVLNVCKEAVDLREANGPQSKALYVYPPNVESSPELPKH
IYAKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPVD
NFTMPSYSRRISTATPYMNGEASVKPLWSINSSLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGMEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMVVIEEHANWTISRELGFNYSHAGLSNRIARDSELRESDKEQLRAVCNRDPL
SEITEQEKDFLWSNRHYCLNTPEILPKLLLAVKWNSRDEVAQMYCLLKDWPPIKPEQAME
LLDCNYPDPMVRAFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLELYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFSSPLNPAHQLGTLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGIKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTRDFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
>A0A8D2F6W9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Theropithecus gelada|TrEMBL
MELENYEQPVVLREDNCRRRRRMKPRSVAACLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRVLETSVASDFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPAVSSKAPAESHSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDTCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
>A0A6P7WZF6|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Microcaecilia unicolor|TrEMBL
MPPRPSSGELWGLHLMPPRIMVDCCIPNGMIVTLECLREATLLGIKHNLFKEARKYPLFH
LLQDESSYIFVGVTQEAEREEFYDETRRLCDLRLFQPILKVIEPVGNREEKILNREIGFA
IGMPICEFEMVKDPEVQEFRRNILSVCKEAMDLREASGSHSQALYVYPPNVESTPELPKH
IYNKLDKGLIIVTIWVIVFPNNDKQKYTLKIPHDCLPEQVIADAIRKKTRSMHLSPEQLK
LCVQEYQGKYILKVCGCDEYLLEKYPFSQYKYIRNCITIGRLPHLMLMSKESLYSQLPAN
IFIMPSYARRSVTSCYMNGDVPTKSLWSINSLLRIRILCATYVNVNIRDIDKIYVRTGIY
HGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYLTDLPRAARLCLSICSVKGRKGAKEEHCP
LAWGNINLFDYKDTLVAGKMALNLWPVPHGLEDLLNPIGVGGSNPNKSNRLARDSSLIEN
EMEQLRNICNRDPLSEITEQEKDFLWRHRQYCINIPETLPKLLLSVKWNSRDEVTQMYCL
LREWPLIKPELSLELLDCNFPDPMVREFALKCLVKGLTDDKLSQYLIQLVQVLKYEQYLD
NPLARFLIKKALTNQRIGHFFFWHLKSEMHSKTVSQRFGLMLEAFCRGCGMYLKHLNRQV
EAMEKLINLTDILKQEKKDETQKMQMKFLMEQMRRPAYMEALQGFICPLNPVHQLGNLRL
EECRIMSSAKRPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIRIMENMWQN
QGQDLRMLPYGCLSIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWLKDKNK
GEGYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFG
YKRERVPFVLTQDFLIVISKGVQECTKTKEFERFQEMCYKAYLVIRQQANLFINLFSMML
GSGMPELQSFDDIAYLRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMP
LSEAGHD
>A0A7L2L5G9|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Zosterops hypoxanthus|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEILLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDET
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRVCGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFRCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L4DG68|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Eurystomus gularis|TrEMBL
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLR
>A0A6I8QFB5|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xenopus tropicalis|TrEMBL
MKKETLLCRGNMLASGMELDSYEQPVVLRDENQRRRRRMRPHSATSNMFPMEQIPIEFIL
PTSNRCSKVQETMLLEVAGNCSVEQMKAQIWMHAIEKSHNSDFYQRLTPDQFLLQYQKKG
QWYEIYDKHQVIQTLDCIMYWKVLQKTVGKIHIVQKEKIPEEMIEYQKTLNYLIGYDVTD
VSNVHDDELEFTRRRLVTPRMIELSRRDARLYSMDPWVTCKSLPEYLCQRIISNSIFIII
HKGMTSHTIRVSIDDTPDVILHSFFTKMAKKKSLLDISEENSELDFVLRVCGRDEYIIGN
APIKDFHWIRQCIKNGQEIHLVLEKPPDPLMDEVQKEQWPLVDDCTGVTGYHEQLTIEGK
DHEKIFTISLWDCNRKFRVKIIGIDIPVLPKNTELIAFVEANIQHGQQVLSQRRTTCKPF
TEEVLWNSWLEFDIKIKDLPKGALLNLQIFCGKAPTASNKSIVQSPESTASDSKCKNQLL
YYVNLLLIDHRFLLRQGEYVLHMWKIPGKGEEQGSINADKLTSATNPDKETSMAISISLD
KYCHPVALPKHKLVCDPELERPRTEMPNQLRKQLEEIIATDPLHPLTPEDKELLWHFRSE
IVKHPEAYPKLLSSVKWGQQEMVAKTYQLLSKREAWDDCSLDVGLTIQLLDCNFSDENVR
AMAVQKLESLQDDDVLHYLLQLVQAVKFEPYHDSALSRFLLKRALQSKRIGHFLFWFLRS
EIAQSMHYQQRFAVILEAYLRGCGKAMLDDFTRQVQVTEILHKVTMEIKSVSAEKYDVTS
QVITQLRQKLEKLQNSKLPDKLPDSFRVPYDPGLRAGSLVVEKCKVMASKKKPLWLEFKC
SDTTALSNETIGIIFKHGDDLRQDMLILQILRIMGSIWEAESLDLCLLPYGCISTGNKIG
MIEIVKDATTIAQIQQSTVGNTGAFKDEVLSQWLKEKCPIEEKFSAAVERFVYSCAGYCV
ATFVLGIGDRHNDNIMVTESGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGT
SGKKTSQYFNKFQDVCVKAYLALRHHTNLMIILFSMMLMTVCAEAYNPDEEDDDTETKVI
YPKTDDQRNRLQEACKDILLFKSLDQEQMSQVLDAMFEKLVKCGEHVIDQGDDGDNFYVI
DRGTYDIFVKSDGVVRCVGAYDNRGSFGELALMYNTPRAATIVATSVGSIWGLDRATFRR
IIVKNNAKKKRMYENFIESLPFLKSLEFSERLKVVDVIGTKTYYDGEQIIAQGDGADSFY
IVESGEVRINMKSKSKPDAETNEAVEIARCTRGQYFGELALVTNKPRAASAYAVGNVKCL
VMDVQAFERLLGPCMEIMKRNIANYEEQLVALFGTNMDITDPST
>A0A7L3PLZ1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xiphorhynchus elegans|TrEMBL
MELEDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSSKHTKVPEMILLE
IAGNCTVEQMKAQVWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYIIGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPNEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRLKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQRRTSSKPFTEEVLWNVWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSTKTNLQSHESSNSDSKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRIPSD
AQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKEVWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVIAQLRQKLEKLQSS
KLPESFRVPYDPALRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKEKCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQDVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A8C5TWQ3|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Malurus cyaneus samueli|TrEMBL
MELGDHEQPVVMREENKRRRRRMKPHCTSSSFSSMELISIEFILPTSNKHTKAPEIMLLE
IAGNCTVEQMKAQIWMRAIEMSQTTDFYHAFTPDQFILQYQKKGQWYEIYDKHQVLQTLD
CILYWKVLQKKVGKIYVVQKQKPSEEVQEFQRQLNDLIGYDVTDVSNVHDDELEFTRRRL
VTPRMIEVACRDPKLYAMHPWTTSKPLPEYLFKKITNNNIFIIIHRGTTSQKIKVSIDDT
PDMILHSFFTKMAKKKSLMDIPEDHSELDFVLRICGRDEYITGETPIKDFHWIRQCLKNG
EEIHLVLDNPPDPSEDEVQKEEWPLVDDCTGVTGYHEQLTIDGKDHERVFTISLWDCNRK
FRVKIIGIDIPVLPRNTDLTVFVEANIQHGQQLLSQKRTSSKPFTEEVLWNIWLEFDIKI
KDLPKGALLNLQIYCGKAQGPSAKTNLQSHESSNSDAKCKTQLLYYVNLLLIDHRFLLRS
GEYVLHMWKIPGKGEEQGSINADKLTSATNPDKENSMAISIVLDKYCHPIALPKHRISSD
PQGDRTRAEMPNQLRKQLEEIIATDPLNPLSPEDKELLWHFRYESIKHPKAYPKLLSSVK
WGQQEIVAKTYQLLAKKESWDQSTLDVGLTMQLLDCNFSDENVRAMAVQKLESLEDDDVL
HYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSMHYQQRFAVIL
EAYLRGCGKAMLHDFMKQVQVIELLHKVTMEIKSVSAEKYDVTSQVITQLRQKLEKLQGS
KLPESFRVPYDPGLRAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDD
LRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGNKIGMIEIVKDATTIAKIQQSTVG
NTGAFKDEILNQWLKERCMIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITET
GNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLYVMGTSGKKTSLHFHKFQEVCVKAY
LALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKHFLDQIEVCRD
KGWTVQFNWFLHLVLGIKQGVEKHSA
>A0A7L3NY27|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Xiphorhynchus elegans|TrEMBL
MPPGIYCPTEFWSKGENQNIQVDFLLPTGIYLNLCVPCNASLGTIKQVVWKHAQYEPLYH
MLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRAKKVINSQISLL
IGKGLHEFDSVQDPEVNDFRTKMCQFCEERAARRQQLGWAAWMEYNFPLQLEPLAKGFGT
GSLQTPTKNIFVNVKFQSGGESFTFQISPKELPLTLMSYAIKKQATVFRHETLQRAEDYT
LQVNGKWEFLYGSHPLYQFQYIRSCLHRGLTPHLTMVHCSAIIAMRDEQTNCIASPPKMA
PKPPPLPKKKPNYGSLWSLEQPFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
VNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSVAP
HPVYYPSFEQLLELGRNGEQPRAAPEDPEEKLQLREILERRSHTELYEHEKDLVWKMRYD
IRDQYPQALAKLLIITKWNKHEDVAQMIFLLQTWPELPVLNALELLDFSFPDRYVGSFAI
NSLKKLTDHDVFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLRSEMHV
PAVSLRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTKEMMHV
CMKQETYREALSHLQSPLNPNIILTEVCVDQCTFMDSKMKPLWIVFNNEETGGGGVGIIF
KNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDTIANIQ
LNKSNMVATAAFNKDALLNWLKSKNPGDALDQAIEEFTLSCAGYCVATYVLGIGDRHSDN
IMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNNEKFERFRG
YCERAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALKHFRLK
FNEALRESWKTKVNWLAHNVSKDNRQ
>A0A091KGD1|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Chlamydotis macqueenii|TrEMBL
SRMPPGIYCPVEFWSKGENQNIQVDFLLPTGIYLRLSVSCNASLGTIKQVVWKHAQYEPL
YHMLSDPEAYVFTCINQTAEQQELEDEQRRLCDIQPSLPVLRLVAREGDRVKKVINSQIS
LLIGKGLHEFDSVHDPEVNDFRTKMCQFCEERAAKRQQLSWAAWMEYNFPLQLEPTAKSL
GTGSLPTPSKNIFVNIKFQSGGESFTFHISPKEFPITLMSYAIKKQATVFRHETLDNPED
YTLQVNGKCEYLYGNYPLYQFQYIRSCLHRGLTPHLTMVHSSTIIAMRDEQTNCITSPPK
MAAKPPPLPKKKPNYGSLWSLEQSFYIELVQGSKVNADERMKLVVQAGLFHGNEMLCKTV
SSSEVNVCSEPVWKQRLDFDINICDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPI
AWVNVMLFDYKDQLKTGECCLHMWSSFPDEKGELLNPMGTVQCNPNTESAAALVICFPSV
VSHPVYYPSFEQVGDIDTFWEAQKFPGFAGGGAYSKLQLKEILERRSHTELYEHEKDLVW
KMRYDICDQYPQALAKLLIITKWNKHEDVAQMISLLQTWPELPVLNALELLDFNFPDRYV
GSFAINSLKKLTDHELFQYLLQLVQVLKYESYLDCELTKFLLDRALSNRKIGHFLFWHLR
SEMHVPAVALRFGLILEAYCRGSTHHMKVLMKQGEALNKMKALNDFVKVSSQKATKPQTK
EMMHMCMKQETYLEALSHLQSPLNPNIILAEVCVDQCTFMDSKMKPLWIVFNNEETGGGG
VGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDKTGLIEVVMHSDT
IANIQLNKSNMVATAAFNKDALLNWLKSKNPGTTEIQTCDSLTFSCSGYCVATYVLGIGD
RHSDNIMIRETGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKF
ERFRDYCEKAYMILRRHGLLFLHLFALMKAAGLPELSCSKDIQYLKDSLALGKTDEEALK
HFRLKFNEALRESWKTKVNWLAHNVSKDNR
>P27986|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Homo sapiens|Swiss-Prot
MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYN
ETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGSSKTEADVEQQALTLPDLAE
QFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVH
VLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTL
QYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEWNE
RQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDA
STKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKL
DVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMK
RTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIID
SRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGN
ENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACS
VVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA
QQRR
>Q9W1M7|phosphatidylinositol-4,5-bisphosphate 3-kinase|EC 2.7.1.153|Drosophila melanogaster|TrEMBL
MDQPDDHFRYIHSSSLHERVQIKVGTLEGKKRQPDYEKLLEDPILRFSGLYSEEHPSFQV
RLQVFNQGRPYCLPVTSSYKAFGKRWSWNEWVTLPLQFSDLPRSAMLVLTILDCSGAGQT
TVIGGTSISMFGKDGMFRQGMYDLRVWLGVEGDGNFPSRTPGKGKESSKSQMQRLGKLAK
KHRNGQVQKVDWLDRLTFREIEVINEREKRMSDYMFLMIEFPAIVVDDMYNYAVVYFEPE
GDVKYKLPAKPKLVSVPDSEIQMENLVERKHHRLARSERSGISDRDAKPTASIRDQLHTI
VYRYPPTYVLSSEEQDLVWKFRFYLSSHKKALTKFLKCINWKLEDEVTQALWMLANWAPM
DVEDALELLSPTFTHPQVRKYAVSRLAQAPDEDLLLYLLQLVQALKYEDPRHIVHLHGCI
FPERDVVRSILDDNGSLLDQSSLSDLSATSSGLHGSVIPANQRAASVLAAIKSDKSVSPG
SAGGSGSGGQGSVALPNPSAPATPGSSSLPCDSNSNALMLAEGISFGSVPANLCTFLIQR
ACTNATLANYFYWYLSIEVEEVESVRKQDERAHDMYAMVLKMFLKVLENGNFNLRGIFYN
LRKQRRFIDELVKLVKLVAKEPGNRNKKTEKFQKLLAEQDMFKVNFTNFEPIPFPLDPEI
YITKIVPMRTSLFKSALMPAKLTFVTSIAHHEYAAIFKHGDDLRQDQLILQMITLMDKLL
RRENLDLKLTPYKVLATSSKHGFLQYVDSCTVAEVLAREGNIHNFFRKHHPCDNGPYGIS
AEVMDTYIKSCAGYCVITYLLGVGDRHLDNLLLTTNGKLFHIDFGYILGRDPKPMPPPMK
LSKEMVEAMGGISSEHHHEFRKQCYTAYLHLRRHANVMLNLFSLMVDATVPDIALEPDKA
VKKVEENLQLGLTDEEAVQHLQSLLDVSITAVMPALVEQIHRFTQYWRK