1.1.1.160: dihydrobunolol dehydrogenase
This is an abbreviated version!
For detailed information about dihydrobunolol dehydrogenase, go to the full flat file.
Reaction
Synonyms
bunolol reductase, dehydrogenase, dihydrobunolol
ECTree
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Substrates Products
Substrates Products on EC 1.1.1.160 - dihydrobunolol dehydrogenase
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REACTION DIAGRAM
(+,-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone + NADPH
(+,-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol + NADP+
-
i.e. bunolol, r, also acts more slowly with NAD+
i.e. dihydrobunolol
r
(+,-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone + NADPH
?
-
i.e. bunolol, metabolism of bunolol, a potent beta-adrenoceptor blocking agent in human liver
-
-
?