1.1.1.192: long-chain-alcohol dehydrogenase
This is an abbreviated version!
For detailed information about long-chain-alcohol dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.192
-
1.1.1.192
-
dehydrogenases
-
sls
-
zinc-dependent
-
d-mannitol
-
2-dehydrogenase
-
d-fructose
-
glutathione-dependent
-
hydride
-
nostoc
-
beta-oxidation
-
nose
-
n-alkanes
-
glycerol-3-phosphate
- 1.1.1.192
- dehydrogenases
- sls
-
zinc-dependent
- d-mannitol
-
2-dehydrogenase
- d-fructose
-
glutathione-dependent
-
hydride
- nostoc
-
beta-oxidation
-
nose
- n-alkanes
- glycerol-3-phosphate
Reaction
Synonyms
ADH, ADH1, ADH2, dehydrogenase, long-chain alcohol, fatty alcohol oxidoreductase, long-chain alcohol dehydrogenase, long-chain alkyl alcohol dehydrogenase, long-chain dehydrogenase, NAD+-dependent secondary alcohol dehydrogenase, SADH
ECTree
Advanced search results
Substrates Products
Substrates Products on EC 1.1.1.192 - long-chain-alcohol dehydrogenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REACTION DIAGRAM
(2S)-5-hydroxy-2-aminovaleric acid + NAD+ + H2O
(2S)-2-amino-5-oxopentanoate + NADH
-
no activity with the (2R)-isomer
-
-
?
1-octanol + 2 NADP+ + H2O
octanoic acid + 2 NADPH + 2 H+
-
-
-
r
10,12-dihydroxyoctadecanoic acid + NADP+ + H2O
? + NADPH
-
the reaction is catalyzed by mutant enzyme D37S/V39S
-
-
?
10-hydroxyoctadecanoic acid + NAD+ + H2O
9-(nonanoyloxy)nonanoic acid + NADH
-
-
-
-
?
10-hydroxyoctadecanoic acid + NADP+ + H2O
9-(nonanoyloxy)nonanoic acid + NADPH
-
the reaction is catalyzed by mutant enzyme D37S/A38R/V39S/T15I
-
-
?
decanal + NAD+ + H+
decanoic acid + NADH
about 10% of the activity with 1-octanol
-
-
r
dodecanal + NAD+ + H+
dodecanoic acid + NADH
about 10% of the activity with 1-octanol
-
-
r
glycerol + 2 NAD+ + H2O
? + 2 NADH + 2 H+
about 45% of the activity with ethanol
-
-
r
isopropanol + 2 NAD+ + H2O
? + 2 NADH + 2 H+
about 15% of the activity with 1-octanol
-
-
r
(2S,4S)-5-hydroxyleucine + NAD+ + H2O
(4S)-5-oxo-L-leucine + NADH
-
enzyme reaction is part of the biosynthesis of (2S,4S)-4-methylproline
-
-
r
? + 2 NADH + 2 H+
about 45% of the activity with ethanol
-
-
r
1,3-propanediol + 2 NAD+ + H2O
? + 2 NADH + 2 H+
about 5% of the activity with 1-octanol
-
-
r
1,3-propanediol + 2 NAD+ + H2O
? + 2 NADH + 2 H+
about 45% of the activity with ethanol
-
-
r
1,3-propanediol + 2 NAD+ + H2O
? + 2 NADH + 2 H+
about 5% of the activity with 1-octanol
-
-
r
decanoic acid + 2 NADH + 2 H+
about 20% of the activity with ethanol
-
-
r
1-decanol + 2 NAD+ + H2O
decanoic acid + 2 NADH + 2 H+
about 50% of the activity with 1-octanol
-
-
r
1-decanol + 2 NAD+ + H2O
decanoic acid + 2 NADH + 2 H+
about 20% of the activity with ethanol
-
-
r
1-decanol + 2 NAD+ + H2O
decanoic acid + 2 NADH + 2 H+
about 50% of the activity with 1-octanol
-
-
r
dodecanoic acid + 2 NADH + 2 H+
about 17% of the activity with ethanol
-
-
r
1-dodecanol + 2 NAD+ + H2O
dodecanoic acid + 2 NADH + 2 H+
about 30% of the activity with 1-octanol
-
-
r
1-dodecanol + 2 NAD+ + H2O
dodecanoic acid + 2 NADH + 2 H+
about 17% of the activity with ethanol
-
-
r
1-dodecanol + 2 NAD+ + H2O
dodecanoic acid + 2 NADH + 2 H+
about 30% of the activity with 1-octanol
-
-
r
eicosanoic acid + 2 NADH + 2 H+
about 25% of the activity with 1-octanol
-
-
r
1-eicosanol + 2 NAD+ + H2O
eicosanoic acid + 2 NADH + 2 H+
about 3% of the activity with ethanol
-
-
r
1-eicosanol + 2 NAD+ + H2O
eicosanoic acid + 2 NADH + 2 H+
about 3% of the activity with ethanol
-
-
r
1-eicosanol + 2 NAD+ + H2O
eicosanoic acid + 2 NADH + 2 H+
about 25% of the activity with 1-octanol
-
-
r
hexadecanoic acid + 2 NADH + 2 H+
about 10% of the activity with ethanol
-
-
r
1-hexadecanol + 2 NAD+ + H2O
hexadecanoic acid + 2 NADH + 2 H+
about 25% of the activity with 1-octanol
-
-
r
octacosanoic acid + 2 NADH + 2 H+
about 40% of the activity with ethanol
-
-
r
1-octacosanol + 2 NAD+ + H2O
octacosanoic acid + 2 NADH + 2 H+
about 5% of the activity with 1-octanol
-
-
r
octadecanoic acid + 2 NADH + 2 H+
about 15% of the activity with 1-octanol
-
-
r
1-octadecanol + 2 NAD+ + H2O
octadecanoic acid + 2 NADH + 2 H+
about 5% of the activity with ethanol
-
-
r
1-octanol + 2 NAD+ + H2O
octanoic acid + 2 NADH + 2 H+
-
-
-
r
tetracosanoic acid + 2 NADH + 2 H+
about 10% of the activity with 1-octanol
-
-
r
1-tetracosanol + 2 NAD+ + H2O
tetracosanoic acid + 2 NADH + 2 H+
about 30% of the activity with ethanol
-
-
r
tetradecanoic acid + 2 NADH + 2 H+
about 15% of the activity with ethanol
-
-
r
1-tetradecanol + 2 NAD+ + H2O
tetradecanoic acid + 2 NADH + 2 H+
about 30% of the activity with 1-octanol
-
-
r
long-chain carboxylate + NADH
-
enzyme also uses formaldehyde and short chain aliphatic alcohols
-
-
?
long-chain alcohol + NAD+ + H2O
long-chain carboxylate + NADH
-
C17-C-19 alcohols do not serve as a good substrate
-
-
?
long-chain alcohol + NAD+ + H2O
long-chain carboxylate + NADH
-
maximum activity on C14 alcohol
-
-
?
long-chain alcohol + NAD+ + H2O
long-chain carboxylate + NADH
-
C8-C16
-
-
?
long-chain alcohol + NAD+ + H2O
long-chain carboxylate + NADH
-
peroxisomal enzyme is participating in fatty acid degradation
-
-
?
long-chain alcohol + NAD+ + H2O
long-chain carboxylate + NADH
-
microsomal and mitochondrial enzyme may have an indispensable role in lipid biosynthesis
-
-
?
long-chain alcohol + NAD+ + H2O
long-chain carboxylate + NADH
-
long chain n-alcanols up to C12
-
-
r
long-chain alcohol + NAD+ + H2O
long-chain carboxylate + NADH
-
maximal activity with decanol
-
-
?
long-chain alcohol + NAD+ + H2O
long-chain carboxylate + NADH
-
C10-C18
-
-
?
long-chain alcohol + NAD+ + H2O
long-chain carboxylate + NADH
-
enzyme may play an important role in regulating the cellular levels of ether-linked lipids
-
-
?
long-chain alcohol + NAD+ + H2O
long-chain carboxylate + NADH
-
C6-C18 alcohols
-
-
?
long-chain alcohol + NAD+ + H2O
long-chain carboxylate + NADH
-
maximal activity with decanol
-
-
?
long-chain alcohol + NAD+ + H2O
long-chain carboxylate + NADH
-
C17-C-19 alcohols do not serve as a good substrate
-
-
?
long-chain alcohol + NAD+ + H2O
long-chain carboxylate + NADH
-
peroxisomal enzyme is participating in fatty acid degradation
-
-
?
long-chain alcohol + NAD+ + H2O
long-chain carboxylate + NADH
-
microsomal and mitochondrial enzyme may have an indispensable role in lipid biosynthesis
-
-
?
octanoic acid + NADH + H+
-
-
-
r
octanal + NAD+ + H2O
octanoic acid + NADH + H+
-
-
-
r
?
-
substrates are a broad range of alkyl alcohols from ethanol to 1-triacontanol
-
-
?
additional information
?
-
substrates are a broad range of alkyl alcohols from ethanol to 1-triacontanol
-
-
?
additional information
?
-
substrates are a broad range of alkyl alcohols from ethanol to 1-triacontanol
-
-
?
additional information
?
-
substrates are a broad range of alkyl alcohols from ethanol to 1-triacontanol
-
-
?
additional information
?
-
-
the wild type enzyme shows no activity with NADP+
-
-
-
additional information
?
-
-
stereospecific abstraction of the 5pro-S hydrogen
-
-
?