1.1.1.76: (S,S)-butanediol dehydrogenase
This is an abbreviated version!
For detailed information about (S,S)-butanediol dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.76
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1.1.1.76
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saccharolyticum
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s-acetoin
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brevibacterium
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synthesis
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corynebacterium
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klebsiella
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pneumoniae
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s-configuration
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chimera
- 1.1.1.76
- saccharolyticum
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s-acetoin
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brevibacterium
- synthesis
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corynebacterium
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klebsiella
- pneumoniae
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s-configuration
- chimera
Reaction
Synonyms
(2R,3R)-2,3-BDH, (2R,3R)-2,3-butanediol dehydrogenase, (2S, 3S)-BDH, (2S, 3S)-butanediol dehydrogenase, (S,S)-2,3-BDH, (S,S)-2,3-butanediol dehydrogenase, (S,S)-butanediol dehydrogenase, 2,3-BDH, 2,3-butanediol dehydrogenase, acetoin(diacetyl) reductase, AdR, ADS1, ARA1, BDH, budC, ButA, L(+)-2,3-butanediol dehydrogenase (L-acetoin forming), L-(2S,3S)-butanediol dehydrogenase, L-BDH, L-butanediol dehydrogenase, LBDH, mbdh, meso-2,3-butanediol dehydrogenase, More, S-2,3-butanediol dehydrogenase
ECTree
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Inhibitors
Inhibitors on EC 1.1.1.76 - (S,S)-butanediol dehydrogenase
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2-mercaptoethanol
competitive. In crystal structure, the mercaptoethanol molecule is located in the catalytic cleft formed by residues Ser141, Ileu142, Ala143, Phe148, Tyr154, Pro184, Gly185, Ileu186, Met191, Trp192 and Ile195. These residues may also be involved in substrate recognition and in stereospecific redox reactions
additional information
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slight inhibition of 10-20% by organic acids at concentrations of 5 mM: lactate, pyruvate, succinate, acetate and formate
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