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1.13.11.76: 2-amino-5-chlorophenol 1,6-dioxygenase

This is an abbreviated version!
For detailed information about 2-amino-5-chlorophenol 1,6-dioxygenase, go to the full flat file.

Reaction

2-amino-5-chlorophenol
+
O2
=
2-amino-5-chloromuconate 6-semialdehyde

Synonyms

cnbC, CnbcA

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.76 2-amino-5-chlorophenol 1,6-dioxygenase

Inhibitors

Inhibitors on EC 1.13.11.76 - 2-amino-5-chlorophenol 1,6-dioxygenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Ca2+
2 mM, 79% residual activity
Cd2+
2 mM abolishes enzyme activity completely
Co2+
2 mM abolishes enzyme activity completely
Cu2+
2 mM, 2.9% residual activity
EDTA
2 mM, 50% residual activity
Fe2+
2 mM, 57% residual activity. Not inhibitory in presence of ascorbate
H2O2
2 mM, complete loss of activity
Mg2+
2 mM, 91% residual activity
Mn2+
2 mM, 31% residual activity
Ni2+
2 mM abolishes enzyme activity completely
Zn2+
2 mM abolishes enzyme activity completely