1.13.12.1: arginine 2-monooxygenase

This is an abbreviated version!
For detailed information about arginine 2-monooxygenase, go to the full flat file.

Reaction

Synonyms

arginine decarboxy-oxidase, arginine decarboxylase, arginine monooxygenase, arginine oxygenase (decarboxylating), oxygenase, arginine 2-mono-

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)

                1.13.12.1 arginine 2-monooxygenase

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Results	in table
1	CAS Registry Number
7	Cofactor
5	General Stability
6	Inhibitors
3	KM Value [mM]
6	Natural Substrates/ Products (Substrates)
13	Organism
2	Oxidation Stability
5	Pathway
6	pH Optimum
2	Purification (Commentary)
1	Reaction
4	Reaction Type
13	Reference
2	Source Tissue
5	Specific Activity [micromol/min/mg]
31	Substrates and Products (Substrate)
5	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]

Substrates Products

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Substrates Products on EC 1.13.12.1 - arginine 2-monooxygenase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

canavanine + O2

3-guanidoxypropionamide + CO2 + H2O

3 entries

homoarginine + O2

5-guanidinovaleramide + CO2 + H2O

3 entries

L-arginine + O2

4-guanidinobutanamide + CO2 + H2O

8 entries

L-arginine + O2

?

6 entries

additional information

?

-

6 entries

canavanine + O2

3-guanidoxypropionamide + CO2 + H2O

Streptomyces griseus

-

-

439353

-

-

?

canavanine + O2

3-guanidoxypropionamide + CO2 + H2O

Streptomyces griseus

-

-

439354

-

439354

?

canavanine + O2

3-guanidoxypropionamide + CO2 + H2O

Streptomyces griseus

-

i.e. 2-amino-4-(guanidinooxy)butyrate, poor substrate

390102

-

390102

?

homoarginine + O2

5-guanidinovaleramide + CO2 + H2O

Streptomyces griseus

-

-

390102

-

390102

?

homoarginine + O2

5-guanidinovaleramide + CO2 + H2O

Streptomyces griseus

-

-

439353

-

-

?

homoarginine + O2

5-guanidinovaleramide + CO2 + H2O

Streptomyces griseus

-

poor substrate

439354

-

439354

?

L-arginine + O2

4-guanidinobutanamide + CO2 + H2O

Arthrobacter globiformis

-

-

439351, 439355

-

-

?

L-arginine + O2

4-guanidinobutanamide + CO2 + H2O

Brevibacterium helvolum

-

-

439351, 439355

-

-

?

L-arginine + O2

4-guanidinobutanamide + CO2 + H2O

Brevibacterium lipolyticum

-

-

439351

-

-

?

L-arginine + O2

4-guanidinobutanamide + CO2 + H2O

Pimelobacter simplex

-

-

439351

-

-

?

L-arginine + O2

4-guanidinobutanamide + CO2 + H2O

Streptomyces alboviridis

-

-

439353

-

-

?

L-arginine + O2

4-guanidinobutanamide + CO2 + H2O

Streptomyces albus

-

-

439353

-

-

?

L-arginine + O2

4-guanidinobutanamide + CO2 + H2O

Streptomyces griseus

-

-

390102, 439352, 439353, 439354

-

-

?

L-arginine + O2

4-guanidinobutanamide + CO2 + H2O

Streptomyces violaceoruber

-

-

439353

-

-

?

L-arginine + O2

?

Arthrobacter globiformis

-

growth on arginine: arginine oxygenase pathway

439351

-

-

?

L-arginine + O2

?

Arthrobacter globiformis

-

dual route of L-arginine degradation, oxygenase pathway being major route

439355

-

-

?

L-arginine + O2

?

Brevibacterium helvolum

-

growth on arginine: arginine oxygenase pathway

439351

-

-

?

L-arginine + O2

?

Brevibacterium helvolum

-

dual route of L-arginine degradation, oxygenase pathway being major route

439355

-

-

?

L-arginine + O2

?

Brevibacterium lipolyticum

-

growth on arginine: arginine oxygenase pathway

439351

-

-

?

L-arginine + O2

?

Pimelobacter simplex

-

growth on arginine: arginine oxygenase pathway

439351

-

-

?

additional information

?

-

Streptomyces alboviridis

-

highly specific, no reaction aerobically in presence of ferricyanide

439353

-

-

?

additional information

?

-

Streptomyces albus

-

highly specific, no reaction aerobically in presence of ferricyanide

439353

-

-

?

additional information

?

-

Streptomyces griseus

-

no activity with D-amino acids or glycine, L-leucine, L-valine, L-lysine, L-tryptophan

439353

-

-

?

additional information

?

-

Streptomyces griseus

-

no activity with L-lysine

390102

-

-

?

additional information

?

-

Streptomyces griseus

-

highly specific, no reaction aerobically in presence of ferricyanide

439353

-

-

?

additional information

?

-

Streptomyces violaceoruber

-

highly specific, no reaction aerobically in presence of ferricyanide

439353

-

-

?