1.14.13.32: albendazole monooxygenase
This is an abbreviated version!
For detailed information about albendazole monooxygenase, go to the full flat file.
Reaction
Synonyms
albendazol sulfoxidase, albendazole oxidase, albendazole sulfoxidase, lancet fluke NADPH-dependent sulphoxidizing enzyme
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Natural Substrates Products on EC 1.14.13.32 - albendazole monooxygenase
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REACTION DIAGRAM
2 albendazole + 2 NADPH + 2 H+ + 2 O2
(+)-albendazole s-oxide + (-)-albendazole s-oxide + 2 NADP+ + 2 H2O
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additional information
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intestinal bioconversion of the anthelmintic drug albendazole into albendazole sulfoxide by two enzymatic systems, cytochrome P4503A and flavin-containing monooxygenases, overview
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albendazole S-oxide + NADP+ + H2O
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