1.14.19.18: sphingolipid 8-(E)-desaturase
This is an abbreviated version!
For detailed information about sphingolipid 8-(E)-desaturase, go to the full flat file.
Reaction
Synonyms
8 fatty acid desaturase, 8-sphingolipid desaturase, D8A, D8B, D8C, D8D, DELTA8-sphingolipid desaturase, DesB, SLD, sphinganine DELTA8-desaturase
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1.14.19.18 sphingolipid 8-(E)-desaturaseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 1.14.19.18 - sphingolipid 8-(E)-desaturase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(4E)-sphing-4-enine ceramide + ferrocytochrome b5 + O2 + H+
(4E,8E)-sphing-4,8-dienine ceramide + ferricytochrome b5 + H2O
sphinganine + ferrocytochrome b5 + O2 + H+
?
the enzyme shows strong preference for dihydroxylated substrates
-
-
?
(4E)-sphing-4-enine ceramide + ferrocytochrome b5 + O2 + H+
(4E,8E)-sphing-4,8-dienine ceramide + ferricytochrome b5 + H2O
-
-
-
?
(4E)-sphing-4-enine ceramide + ferrocytochrome b5 + O2 + H+
(4E,8E)-sphing-4,8-dienine ceramide + ferricytochrome b5 + H2O
-
-
-
-
?
(4E)-sphing-4-enine ceramide + ferrocytochrome b5 + O2 + H+
(4E,8E)-sphing-4,8-dienine ceramide + ferricytochrome b5 + H2O
-
-
-
-
?
(4E)-sphing-4-enine ceramide + ferrocytochrome b5 + O2 + H+
(4E,8E)-sphing-4,8-dienine ceramide + ferricytochrome b5 + H2O
-
-
-
?
