2.1.1.147: corydaline synthase

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For detailed information about corydaline synthase, go to the full flat file.

Reaction

Synonyms

methyltransferase, protoberberine, protoberberine 13-methyltransferase, S-adenosylmethionine:protoberberine-13C-methyltransferase

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.147 corydaline synthase

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Results	in table
1	CAS Registry Number
1	Inhibitors
1	Ki Value [mM]
3	KM Value [mM]
1	Localization
1	Molecular Weight [Da]
1	Organism
2	Pathway
1	pH Optimum
1	pH Range
1	Purification (Commentary)
1	Reaction
1	Reaction Type
1	Reference
1	Source Tissue
1	Specific Activity [micromol/min/mg]
6	Substrates and Products (Substrate)
3	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]

Substrates Products

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Substrates Products on EC 2.1.1.147 - corydaline synthase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

S-adenosyl-L-methionine + berberine + NADPH + H+

S-adenosyl-L-homocysteine + corydaline + NADP+

Corydalis cava

-

-

485156

-

485156

?

S-adenosyl-L-methionine + columbamine + NADPH + H+

S-adenosyl-L-homocysteine + isocorypalmine + NADP+

Corydalis cava

-

27% of the activity with berberine

485156

-

-

?

S-adenosyl-L-methionine + coptisine + NADPH + H+

S-adenosyl-L-homocysteine + tetrahydrocorysamine + NADP+

Corydalis cava

-

21% of the activity with berberine

485156

-

-

?

S-adenosyl-L-methionine + dihydroberberine + NADPH + H+

S-adenosyl-L-homocysteine + thalictricavine + NADP+

Corydalis cava

-

93% of the activity with berberine

485156

-

485156

?

S-adenosyl-L-methionine + jatrorrhizine + NADPH + H+

S-adenosyl-L-homocysteine + 7,8-dehydrothalictricavine + NADP+

Corydalis cava

-

67% of the activity with berberine

485156

-

-

?

S-adenosyl-L-methionine + palmatine + NADPH + H+

S-adenosyl-L-homocysteine + corydaline + NADP+

Corydalis cava

-

93% of the activity with berberine

485156

-

485156

?