2.1.1.218: tRNA (adenine9-N1)-methyltransferase
This is an abbreviated version!
For detailed information about tRNA (adenine9-N1)-methyltransferase, go to the full flat file.
Reaction
Synonyms
adenosine-specific Trm10, EC 2.1.1.36, hTRMT10B, m1A9 MTase, m1R9-specific TkTrm10, More, SaTrm10, SPOUT MTase, TK0422p, TkTrm10, Trm10, Trm10p (ambiguous), TRMT10B, Trmt10C, tRNA m1A9 methyltransferase, tRNA m1A9 MTase, tRNA m1A9-methyltransferase, tRNA m1R9 methyltransferase, tRNA(m1G9/m1A9)-methyltransferase, tRNA(m1G9/m1A9)MTase
ECTree
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pH Range
pH Range on EC 2.1.1.218 - tRNA (adenine9-N1)-methyltransferase
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5.5 - 9.75
the bifunctional enzyme is active in a pH range 5.5-9.75. The intensity of m1A and m1G spots varies greatly as a function of the pH. At pH 5.5, m1A MTase activity of TK0422p is predominant over m1G. At pH 7 or higher, both m1A and m1G are detected, m1G intensity growing with increasing pH
additional information
pH-rate profiles for the two activities catalyzed by the bifunctional methyltransferase TkTrm10, cf. EC 2.1.1.221