2.1.1.227: 16S rRNA (cytidine1409-2'-O)-methyltransferase
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For detailed information about 16S rRNA (cytidine1409-2'-O)-methyltransferase, go to the full flat file.
Reaction
Synonyms
2'-O-methyltransferase, More, rRNA methylase, rRNA methylase TlyA, TlyA, TlyAII
ECTree
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Expression
Expression on EC 2.1.1.227 - 16S rRNA (cytidine1409-2'-O)-methyltransferase
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in response to capreomycin, cells downregulate TlyA-mediated methylation of 16S and 23S (cf. EC 2.1.1.226) rRNA resulting in decreased drug susceptibility. Incubation with capreomycin during bacterial growth results in a reduced post-transcriptional modification of rRNA at TlyA-dependent sites (1409 in 16S and 1920 in 23S)
the common resistance mutation A1408G is accompanied by a physiological change that involves increased expression of the tlyA gene
in response to capreomycin, cells downregulate TlyA-mediated methylation of 16S and 23S (cf. EC 2.1.1.226) rRNA resulting in decreased drug susceptibility. Incubation with capreomycin during bacterial growth results in a reduced post-transcriptional modification of rRNA at TlyA-dependent sites (1409 in 16S and 1920 in 23S)
in response to capreomycin, cells downregulate TlyA-mediated methylation of 16S and 23S (cf. EC 2.1.1.226) rRNA resulting in decreased drug susceptibility. Incubation with capreomycin during bacterial growth results in a reduced post-transcriptional modification of rRNA at TlyA-dependent sites (1409 in 16S and 1920 in 23S)
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the common resistance mutation A1408G is accompanied by a physiological change that involves increased expression of the tlyA gene
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