2.1.1.262: squalene methyltransferase This is an abbreviated version! For detailed information about squalene methyltransferase, go to the full flat file .
Word Map on EC 2.1.1.262
2.1.1.262
arthrodesis
valgus
hallux
lapidus
screw
ascites
compression
comorbid
tarsometatarsal
anatomical
postoperative
Reaction
2 S-adenosyl-L-methionine
+
squalene =
2 S-adenosyl-L-homocysteine
+
3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene
Synonyms TMT-1, TMT-2, triterpene methyltransferase
ECTree
Systematic Name
Systematic Name on EC 2.1.1.262 - squalene methyltransferase
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S-adenosyl-L-methionine:squalene C-methyltransferase
Two isoforms differing in their specificity were isolated from the green alga Botryococcus braunii BOT22. TMT-1 gave more of the dimethylated form whereas TMT2 gave more of the monomethylated form.