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2.3.1.59: gentamicin 2'-N-acetyltransferase

This is an abbreviated version!
For detailed information about gentamicin 2'-N-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.59

Reaction

acetyl-CoA
+
gentamicin C1a
=
CoA
 +
N2'-acetylgentamicin C1a

Synonyms

AAC(2')-Ia, ACC(2'), acetyltransferase, gentamicin 2'-, gentamicin acetyltransferase II

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.59 gentamicin 2'-N-acetyltransferase

Substrates Products

Substrates Products on EC 2.3.1.59 - gentamicin 2'-N-acetyltransferase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
acetyl-CoA + butirosin
CoA + ?
show the reaction diagram
-
acetylated at 30% the rate of gentamicin C1
-
-
?
acetyl-CoA + dideoxykanamycin
CoA + N2'-diacetyldideoxykanamycin
show the reaction diagram
-
acetylated at 92% the rate of gentamicin C1
-
-
?
acetyl-CoA + gentamicin B
CoA + N2'-acetylgentamycin
show the reaction diagram
-
7% of the activity with gentamicin C1
-
-
?
acetyl-CoA + gentamicin C1
CoA + N2'-acetylgentamicin C1
show the reaction diagram
acetyl-CoA + gentamicin C1a
CoA + N2'-acetylgentamicin C1a
show the reaction diagram
acetyl-CoA + kanamycin B
CoA + N2-acetylkanamycin B
show the reaction diagram
acetyl-CoA + kanamycin C
CoA + N2'-acetylkanamycin C
show the reaction diagram
acetyl-CoA + neomycin B
CoA + N2'-acetylneomycin B
show the reaction diagram
-
acetylated at 10% the rate of gentamicin C1
-
-
?
acetyl-CoA + paromomycin
CoA + N2'-acetylparomomycin
show the reaction diagram
-
-
-
-
?
acetyl-CoA + ribostamycin
CoA + N2'-acetylribostamycin
show the reaction diagram
-
acetylated at 15% the rate of gentamicin C1
-
-
?
acetyl-CoA + sisomicin
CoA + N3'-acetylsisomicin
show the reaction diagram
acetyl-CoA + tobramycin
CoA + N2'-acetyltobramycin
show the reaction diagram
acetyl-CoA of soluble fragments of peptidoglycan + tobramycin
?
show the reaction diagram
N-acetyl-D-glucosamine + tobramycin
D-glucosamine + N2'-acetyltobramycin
show the reaction diagram
additional information
?
-