2.3.1.9: acetyl-CoA C-acetyltransferase This is an abbreviated version! For detailed information about acetyl-CoA C-acetyltransferase, go to the full flat file .
Reaction
2 acetyl-CoA
=
CoA +
acetoacetyl-CoA
Synonyms 2-methylacetoacetyl-CoA thiolase, 3-ketoacyl-CoA (T1)-like thiolase, 3-ketoacyl-CoA thiolase, 3-ketoacyl-coenzyme A thiolase, 3-oxothiolase, A1887, AACT, AACT1, AACT2, ACAT, ACAT1, ACAT2, ACCT, acetoacetyl CoA thiolase, acetoacetyl-CoA acetyltransferase, acetoacetyl-CoA C-acetyltransferase, acetoacetyl-CoA thiolase, acetoacetyl-CoA thiolase T2, acetyl coenzyme A thiolase, acetyl-CoA acetyltransferase, acetyl-CoA C-acetyltransferase, acetyl-CoA:N-acetyltransferase, acetyltransferase, acetyl coenzyme A, ACOAT, ACTRANS, AFUB_000550, AtoB, beta-acetoacetyl coenzyme A thiolase, beta-ketoacyl-CoA thiolase, beta-ketothiolase, CT, cytosolic acetoacetyl-CoA thiolase, cytosolic acetoacetyl-CoA thiolase 1, cytosolic acetoacetyl-CoA thiolase 2, ERG10, Erg10A, HFX_1022, HFX_1023, HFX_6003, HFX_6004, KACT, MmgA, Msed_0656, MSM-13 thiolase, OsAT1, phaA, ReH16_B0759, thiolase II, ThL, Tneu_0249, type II thiolase
ECTree
Source Tissue
Source Tissue on EC 2.3.1.9 - acetyl-CoA C-acetyltransferase
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higher expression levels in the liver, kidney, adrenal gland and ovary
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isoform AACT! is highly expressed in root tips, young leaf, top stem and anther
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mitochondrial acetoacetyl CoA thiolase is decreased by 80% in ulcerative colitis compared with control. Mitochondrial thiolase activity in ulcerative colitis does not correlate with clinical, endoscopic or histological indices of disease severity. Mitochondrial thiolase activity is reduced in the normal right colon mucosa of patients with left-sided ulcerative colitis
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male flower and leaf, second highest expression level
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highest expression level
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higher expression levels in the liver, kidney, adrenal gland and ovary
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expression of AACT in primordia (2.4fold) 33 and 15 d mycelia (2.3 fold) is significantly higher than in 9 d mycelia
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higher expression levels in the liver, kidney, adrenal gland and ovary
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highest expression in roots and petals
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expression of AACT in primordia (2.4fold) 33 and 15 d mycelia (2.3 fold) is significantly higher than in 9 d mycelia
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etiolated
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isoform AACT! is primarily expressed in the vascular system
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low ACT1 expression
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isoform AACT! is highly expressed in root tips, young leaf, top stem and anther
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no significant difference in expression among roots, stems and leaves
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and male flower, second highest expression level
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higher expression levels in the liver, kidney, adrenal gland and ovary. mRNA levels in the liver rapidly increase after hatching, with a maximum on d 5 posthatching, after which they gradually decreased to adult levels
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acetoacetyl-CoA thiolase activity in isolated liver mitochondria is markedly increased in the ketotic dogfish compared to the recently captured fish
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low ACT1 expression
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isoform AACT! is highly expressed in root tips, young leaf, top stem and anther
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highest expression in roots and petals
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no significant difference in expression among roots, stems and leaves
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isoform AACT! is highly expressed in root tips, young leaf, top stem and anther
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no significant difference in expression among roots, stems and leaves
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additional information
ACT2 is expressed at relatively high level in all plant tissues
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additional information
ACT2 is expressed at relatively high level in all plant tissues
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additional information
the expression of ACT1 is restricted to roots and inflorescences and its transcript is present at very low levels
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additional information
the expression of ACT1 is restricted to roots and inflorescences and its transcript is present at very low levels
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additional information
immunoreactive protein is detected in all the tissues
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immunoreactive protein is detected in all the tissues
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additional information
expression is found in all tissues
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expression is found in all tissues
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additional information
Osat1 is expressed in all adult tissues
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Osat1 is expressed in all adult tissues
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additional information
mRNA is ubiquitously expressed in 6 adult tissues including pheromone gland
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mRNA is ubiquitously expressed in 6 adult tissues including pheromone gland
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