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2.3.1.9: acetyl-CoA C-acetyltransferase

This is an abbreviated version!
For detailed information about acetyl-CoA C-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.9

Reaction

2 acetyl-CoA =

CoA
+
acetoacetyl-CoA

Synonyms

2-methylacetoacetyl-CoA thiolase, 3-ketoacyl-CoA (T1)-like thiolase, 3-ketoacyl-CoA thiolase, 3-ketoacyl-coenzyme A thiolase, 3-oxothiolase, A1887, AACT, AACT1, AACT2, ACAT, ACAT1, ACAT2, ACCT, acetoacetyl CoA thiolase, acetoacetyl-CoA acetyltransferase, acetoacetyl-CoA C-acetyltransferase, acetoacetyl-CoA thiolase, acetoacetyl-CoA thiolase T2, acetyl coenzyme A thiolase, acetyl-CoA acetyltransferase, acetyl-CoA C-acetyltransferase, acetyl-CoA:N-acetyltransferase, acetyltransferase, acetyl coenzyme A, ACOAT, ACTRANS, AFUB_000550, AtoB, beta-acetoacetyl coenzyme A thiolase, beta-ketoacyl-CoA thiolase, beta-ketothiolase, CT, cytosolic acetoacetyl-CoA thiolase, cytosolic acetoacetyl-CoA thiolase 1, cytosolic acetoacetyl-CoA thiolase 2, ERG10, Erg10A, HFX_1022, HFX_1023, HFX_6003, HFX_6004, KACT, MmgA, Msed_0656, MSM-13 thiolase, OsAT1, phaA, ReH16_B0759, thiolase II, ThL, Tneu_0249, type II thiolase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.9 acetyl-CoA C-acetyltransferase

Source Tissue

Source Tissue on EC 2.3.1.9 - acetyl-CoA C-acetyltransferase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
higher expression levels in the liver, kidney, adrenal gland and ovary
Manually annotated by BRENDA team
isoform AACT! is highly expressed in root tips, young leaf, top stem and anther
Manually annotated by BRENDA team
-
mitochondrial acetoacetyl CoA thiolase is decreased by 80% in ulcerative colitis compared with control. Mitochondrial thiolase activity in ulcerative colitis does not correlate with clinical, endoscopic or histological indices of disease severity. Mitochondrial thiolase activity is reduced in the normal right colon mucosa of patients with left-sided ulcerative colitis
Manually annotated by BRENDA team
male flower and leaf, second highest expression level
Manually annotated by BRENDA team
highest expression level
Manually annotated by BRENDA team
higher expression levels in the liver, kidney, adrenal gland and ovary
Manually annotated by BRENDA team
-
expression of AACT in primordia (2.4fold) 33 and 15 d mycelia (2.3 fold) is significantly higher than in 9 d mycelia
Manually annotated by BRENDA team
higher expression levels in the liver, kidney, adrenal gland and ovary
Manually annotated by BRENDA team
highest expression in roots and petals
Manually annotated by BRENDA team
-
expression of AACT in primordia (2.4fold) 33 and 15 d mycelia (2.3 fold) is significantly higher than in 9 d mycelia
Manually annotated by BRENDA team
isoform AACT! is primarily expressed in the vascular system
Manually annotated by BRENDA team
additional information