2.4.1.149: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase

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For detailed information about N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase, go to the full flat file.

Word Map on EC 2.4.1.149

2.4.1.149

glycans

muscular

dystrophy

glycosyltransferases

dystroglycanopathies

walker-warburg

bulb

olfactory

alpha-dystroglycan

gmppb

keratan

laminin-binding

pathfinding

glomeruli

pomgnt1

medicine

Reaction

beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R

N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R

Synonyms

acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-acetyllactosaminide beta1-->3-, B3gnt1, B3GNT3, beta-1,3-N-acetylglucosaminyltransferase 1, beta-1,3-N-acetylglucosaminyltransferase-3, beta1,3-N-acetylglucosaminyltransferase, beta1,3-N-acetylglucosaminyltransferase-7, beta1-3 N-acetylglucosaminyltransferase-1, beta3-N-acetylglucosaminyltransferase 1, beta3GlcNAcT, beta3Gn-T7, beta3GnT1, beta3GnT7, EC 2.4.1.163, Galbeta1-->4GlcNAc-R beta1-->3 N-acetylglucosaminyltransferase, GnT-I, i-GlcNAc transferase, i-GlcNAcT, IGnT, JHP1032, N-acetyllactosamine beta(1-3)N-acetylglucosaminyltransferase, poly-N-acetyllactosamine extension enzyme, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1, UDP-GlcNAc:Galbeta1-->4GlcNAcbeta-Rbeta1-->3-N-acetylglucosaminyltransferase, UDP-GlcNAc:Galbeta1-4Glc(NAc) beta-1,3-N-acetylglucosaminyltransferase, UDP-GlcNAc:GalR, beta-D-3-N-acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-acetyllactosaminide beta1-->3-acetylglucosaminyltransferase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.149 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase

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Results	in table
12	Activating Compound
23	AA Sequence
3	Application
1	CAS Registry Number
6	Cloned(Commentary)
113	Disease/ Diagnostics
2	Expression
2	General Information
19	Inhibitors
25	KM Value [mM]
7	Localization
20	Metals/Ions
4	Molecular Weight [Da]
24	Natural Substrates/ Products (Substrates)
21	Organism
6	Pathway
23	PDB ID
9	pH Optimum
1	pH Range
3	Posttranslational Modification
2	Purification (Commentary)
1	Reaction
1	Reaction Type
21	Reference
43	Source Tissue
3	Specific Activity [micromol/min/mg]
2	Storage Stability
95	Substrates and Products (Substrate)
4	Subunits
29	Synonyms
1	Systematic Name
11	Temperature Optimum [°C]
8	Temperature Stability [°C]

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diagnostics

Homo sapiens

Q9Y2A9

high expression of B3GNT3 is associated with unfavourable disease-free survival and overall survival in NSCLC patients, suggesting that B3GNT3 might be a potential prognostic biomarker for non-small cell lung cancer (NSCLC). B3GNT3 expression is an independent prognostic factor

759552

medicine

2 entries