2.4.1.182: lipid-A-disaccharide synthase
This is an abbreviated version!
For detailed information about lipid-A-disaccharide synthase, go to the full flat file.
Word Map on EC 2.4.1.182
-
2.4.1.182
-
acyltransferase
-
raetz
-
clockwise
-
udp-glcnac
-
lipopolysaccharide
-
paralogue
-
lps
-
udp-2,3-diacylglucosamine
-
castellanii
-
cotranscribed
-
amoebae
-
micelle
-
pneumophila
-
bacteriol
-
acanthamoeba
-
glycerophospholipids
-
resin
-
udp-n-acetylglucosamine
-
synthesis
- 2.4.1.182
- acyltransferase
-
raetz
-
clockwise
- udp-glcnac
- lipopolysaccharide
- paralogue
- lps
- udp-2,3-diacylglucosamine
- castellanii
-
cotranscribed
-
amoebae
-
micelle
- pneumophila
-
bacteriol
-
acanthamoeba
- glycerophospholipids
- resin
- udp-n-acetylglucosamine
- synthesis
Reaction
Synonyms
lcsC, lcsC/lpxB1, Legionella cytotoxic suppressor C, lipid A disaccharide synthase, lipid A disaccharide synthetase, LpxB, More, pgsB, synthase, lipid A disaccharide
ECTree
Advanced search results
Reaction
Reaction on EC 2.4.1.182 - lipid-A-disaccharide synthase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + a lipid X = UDP + a lipid A disaccharide
a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + a lipid X = UDP + a lipid A disaccharide
-
-
-
-
a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + a lipid X = UDP + a lipid A disaccharide
enzyme LpxB catalyzes the nucleophilic attack of the 6'-hydroxyl of lipid X (1) on the anomeric carbon of UDP-DAG (2) with UDP as the leaving group. As for other inverting GT-B enzymes, this reaction is thought to proceed by an SN2 mechanism