2.4.1.221: peptide-O-fucosyltransferase

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For detailed information about peptide-O-fucosyltransferase, go to the full flat file.

Reaction

Synonyms

alpha-6-fucosyltransferase, At3g05320, AtOFT1, core alpha6FucT, fucosyltransferase, guanosine diphosphofucose-glycoprotein, FUT2, GDP-fucose glycoprotein fucosyltransferase, GDP-fucose protein O-fucosyltransferase, GDP-fucose protein O-fucosyltransferase 1, GDP-fucose protein O-fucosyltransferase 2, GDP-fucose:polypeptide fucosyltransferase, GDP-L-fucose-glycoprotein fucosyltransferase, GDP-L-fucose:polypeptide fucosyltransferase, glycoprotein fucosyltransferase, guanosine diphosphofucose-glycoprotein fucosyltransferase, N-acetyl-beta-D-glucosaminide alpha1-->6-fucosyltransferase, N-glycan alpha-6-fucosyltransferase, O-fucosyltransferase, O-fucosyltransferase 1, O-fucosyltransferase O-fut 1, O-fucosyltransferase SPINDLY, O-fucT-1, O-fut1, OFUT1, OFUTI, Pofut1, POFUT2, protein O-fucosyltransferase 1, protein O-fucosyltransferase 2, protein O-fucosyltransferases 1, protein O-fucosyltransferases 2, SPY, TGGT1_273550

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.221 peptide-O-fucosyltransferase

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Results	in table
3281	AA Sequence
6	Application
1	CAS Registry Number
11	Cloned(Commentary)
10	Crystallization (Commentary)
238	Disease/ Diagnostics
2	Expression
56	General Information
3	Inhibitors
7	KM Value [mM]
24	Localization
11	Metals/Ions
2	Molecular Weight [Da]
16	Natural Substrates/ Products (Substrates)
60	Organism
1	Pathway
35	PDB ID
4	pH Optimum
1	pH Range
2	Posttranslational Modification
40	Protein Variants
7	Purification (Commentary)
3	Reaction
2	Reaction Type
56	Reference
38	Source Tissue
1	Specific Activity [micromol/min/mg]
44	Substrates and Products (Substrate)
1	Subunits
103	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Stability [°C]
2	Turnover Number [1/s]

Expression

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Expression on EC 2.4.1.221 - peptide-O-fucosyltransferase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

expression in tumorsphere is significantly higher than in parental adherent cells. Upregulated in esophageal cancer stem-like cell in comparison to adherent cells

Homo sapiens

Q9H488, Q9Y2G5

759318

POFUT1 mRNA expression is upregulated in oral squamous cell carcinoma cells

Homo sapiens

Q9H488

736272