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2.4.1.27: DNA beta-glucosyltransferase

This is an abbreviated version!
For detailed information about DNA beta-glucosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.27

Reaction

UDP-alpha-D-glucose
+
5-hydroxymethylcytosine containing DNA
=
UDP
+
beta-D-glucosyl-5-hydroxymethylcytosine containing DNA

Synonyms

beta-GT, BGT, glucosyltransferase, uridine diphosphoglucose-deoxyribonucleate beta-, GT-B glycosyltransferase, More, T4 beta-glucosyl transferase, T4 beta-glucosyltransferase, T4 phage beta-glucosyltransferase, T4-beta-glucosyl transferase, T4-HMC-beta-glucosyl transferase, UDP glucose-DNA beta-glucosyltransferase, uridine diphosphoglucose-deoxyribonucleate beta-glucosyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.27 DNA beta-glucosyltransferase

Application

Application on EC 2.4.1.27 - DNA beta-glucosyltransferase

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
analysis
Tequatrovirus T4
-
use of recombinant enzyme to estimate global 5-hydroxymethyl cytosine content in a variety of genomic DNAs. Most of the genomic DNAs derived from vertebrate tissue and cell lines contain 5-hydroxymethyl cytosine. DNA from mouse, human, and bovine brains displays 0.5?0.9% of the total nucleotides as 5-hydroxymethyl cytosine, which is higher compared to the levels found in other tissues. A comparison between cancer and healthy tissue genomes suggests a lower percentage of 5-hydroxymethyl cytosine in cancer
medicine
Tequatrovirus T4
-
a comparison between cancer and healthy tissue genomes suggests a lower percentage of 5-hydroxymethyl cytosine in cancer