2.4.1.341: alpha-1,2-colitosyltransferase

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For detailed information about alpha-1,2-colitosyltransferase, go to the full flat file.

Reaction

Synonyms

alpha1,2-ColT, wbgN

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.341 alpha-1,2-colitosyltransferase

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Results	in table
1	Cloned(Commentary)
3	kcat/KM [mM/s]
3	KM Value [mM]
2	Localization
1	Metals/Ions
1	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
2	Organism
1	Pathway
1	pH Optimum
1	pH Range
1	Purification (Commentary)
1	Reaction
2	Reference
6	Substrates and Products (Substrate)
2	Subunits
4	Synonyms
1	Systematic Name
3	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 2.4.1.341 - alpha-1,2-colitosyltransferase

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SYSTEMATIC NAME

IUBMB Comments

GDP-beta-L-colitose:beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine L-colitosyltransferase (configuration-inverting)

The enzyme, characterized from the bacterium Escherichia coli O55:H7, participates in the biosynthesis of an O-antigen. The reaction involves anomeric inversion, and does not require any metal ions. The enzyme is highly specific towards the acceptor, exclusively recognizing lacto-N-biose, but can accept GDP-L-fucose as the donor with almost the same activity as with GDP-beta-L-colitose.