2.4.2.49: neamine phosphoribosyltransferase
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For detailed information about neamine phosphoribosyltransferase, go to the full flat file.
Reaction
Synonyms
btrL, neoM
ECTree
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Systematic Name
Systematic Name on EC 2.4.2.49 - neamine phosphoribosyltransferase
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neamine:5-phospho-alpha-D-ribose 1-diphosphate phosphoribosyltransferase
Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including ribostamycin, neomycin and butirosin. The enzyme requires a divalent metal ion, optimally Mg2+, Ni2+ or Co2+.