2.5.1.120: aminodeoxyfutalosine synthase
This is an abbreviated version!
For detailed information about aminodeoxyfutalosine synthase, go to the full flat file.
Reaction
Synonyms
AFL synthase, aminofutalosine synthase, MqnE, TTHA0804
ECTree
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Reference
Reference on EC 2.5.1.120 - aminodeoxyfutalosine synthase
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Mahanta, N.; Fedoseyenko, D.; Dairi, T.; Begley, T.P.
Menaquinone biosynthesis: formation of aminofutalosine requires a unique radical SAM enzyme
J. Am. Chem. Soc.
135
15318-15321
2013
Thermus thermophilus (Q5SK48)
Joshi, S.; Fedoseyenko, D.; Mahanta, N.; Ducati, R.G.; Feng, M.; Schramm, V.L.; Begley, T.P.
Antibacterial strategy against H. pylori Inhibition of the radical SAM enzyme MqnE in menaquinone biosynthesis
ACS Med. Chem. Lett.
10
363-366
2019
Campylobacter jejuni, Helicobacter pylori (O25368), Helicobacter pylori, Helicobacter pylori ATCC 700392 (O25368)
Joshi, S.; Mahanta, N.; Fedoseyenko, D.; Williams, H.; Begley, T.P.
Aminofutalosine synthase Evidence for captodative and aryl radical intermediates using beta-scission and SRN1 trapping reactions
J. Am. Chem. Soc.
139
10952-10955
2017
Thermus thermophilus
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