2.6.1.36: L-lysine 6-transaminase

This is an abbreviated version!
For detailed information about L-lysine 6-transaminase, go to the full flat file.

Reaction

Synonyms

aminotransferase, lysine 6-, EC 2.6.1.68, L-lysine-alpha-ketoglutarate 6-aminotransferase, L-lysine-alpha-ketoglutarate aminotransferase, L-lysine-epsilon-aminotransferase, LAT, lysine 6-aminotransferase, lysine epsilon-aminotransferase, lysine epsilon-transaminase, lysine-epsilon-aminotransferase, lysine:2-ketoglutarate 6-aminotransferase, Rv3290c

ECTree

     2 Transferases

         2.6 Transferring nitrogenous groups

             2.6.1 Transaminases

                2.6.1.36 L-lysine 6-transaminase

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Results	in table
6	Activating Compound
2110	AA Sequence
2	Application
1	CAS Registry Number
4	Cloned(Commentary)
14	Cofactor
7	Crystallization (Commentary)
2	Expression
7	General Information
1	General Stability
27	IC50 Value
43	Inhibitors
18	KM Value [mM]
19	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
254	Organism
3	Pathway
8	PDB ID
10	pH Optimum
3	pH Range
1	pH Stability
9	Protein Variants
11	Purification (Commentary)
3	Reaction
2	Reaction Type
39	Reference
8	Specific Activity [micromol/min/mg]
1	Storage Stability
73	Substrates and Products (Substrate)
8	Subunits
33	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
6	Temperature Stability [°C]
6	Turnover Number [1/s]

Temperature Stability

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Temperature Stability on EC 2.6.1.36 - L-lysine 6-transaminase

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TEMPERATURE STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

50.6

Mycobacterium tuberculosis

P9WQ77

melting temperature

739738

52.1

Mycobacterium tuberculosis

P9WQ77

melting temperature in presence of inhibitor 4-ethoxy-2-phenyl-2,3-dihydro-1,3-thiazole-5-carboxamide

739738

55

[Flavobacterium] lutescens

-

pH 6.0-7.5, 5 min, stable, partially purified enzyme

637017

65

[Flavobacterium] lutescens

-

5 min, activated by heat treatment

637022

75

[Flavobacterium] lutescens

-

5 min, inactivation

637022

additional information

[Flavobacterium] lutescens

-

pyridoxal 5'-phosphate, 0.1 mM, or 2-mercaptoethanol, 0.02%, protects against heat inactivation

637017