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2.6.1.54: pyridoxamine-phosphate transaminase

This is an abbreviated version!
For detailed information about pyridoxamine-phosphate transaminase, go to the full flat file.

Reaction

pyridoxamine 5'-phosphate
+
2-oxoglutarate
=
pyridoxal 5'-phosphate
 +
D-glutamate

Synonyms

aminotransferase, pyridoxamine phosphate, pyridoxamine 5'-phosphate transaminase, pyridoxamine 5'-phosphate-alpha-ketoglutarate transaminase

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.54 pyridoxamine-phosphate transaminase

Activating Compound

Activating Compound on EC 2.6.1.54 - pyridoxamine-phosphate transaminase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4-aminobutyrate
-
stimulation, 177% of non-stimulated activity
D-asparagine
-
stimulation, 112% of non-stimulated activity
D-cysteine
-
stimulation, 135% of non-stimulated activity
D-methionine
-
stimulation, 127% of non-stimulated activity
DL-Ornithine
-
stimulation, 112% of non-stimulated activity
glycine
-
stimulation, 137% of non-stimulated activity
L-asparagine
-
stimulation, 112% of non-stimulated activity
L-glutamate
-
stimulation, 166% of non-stimulated activity
L-lysine
-
stimulation, 105% of non-stimulated activity
L-methionine
-
stimulation, 114% of non-stimulated activity
L-ornithine
-
stimulation, 112% of non-stimulated activity
additional information
-
stimulating effect of amino compounds may be caused by disappearance of the inhibitory product of the reaction, pyridoxal 5'-phosphate, forming the corresponding Schiff base
-