2.7.1.199: protein-Npi-phosphohistidine-D-glucose phosphotransferase

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For detailed information about protein-Npi-phosphohistidine-D-glucose phosphotransferase, go to the full flat file.

Reaction

Synonyms

D-glucose PTS permease, D-glucose transporter, domain A of enzyme II, EC 2.7.1.69, ecIICBGlc, EIIAGlc, EIIBCA, EIICBAGlc1, EIICBAGlc2, EIICBGlc, EIIGlc, enzyme II-BGlc, enzyme IICBGlc, enzyme IIGlc, ExuT, glcA, glucose permease, glucose PTS permease, glucose specific transporter, glucose transporter, glucose-permease, glucose-PTS transporter, glucose-specific carrier, glucose-specific EII complex, glucose-specific enzyme I1, glucose-specific enzyme II, glucose-specific enzyme IICBA PTS component, glucose-specific permease, glucose-specific phosphotransferase system, glucose-specific PTS enzyme II, glucose-specific PTS permease, glucose-specific transporter of phosphoenolpyruvate:carbohydrate phosphotransferase system, glucose-specific transporter of the phosphotransferase system, high affinity Glc transporter, II-BGlc, IIAGlc, IIBCGlc, IIBGlc, IICB, IICBA Glc, IICBGlc, IICglc, IIGlc, non-PTS sugar transporter, phosphoenolpyruvate-dependent glucose phosphotransferase system, phosphoenolpyruvate-dependent glucose-phosphotransferase system, PTS IIC glucose transporter, PtsG, ptsG-I, PTSGlc, sugar permease

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.199 protein-Npi-phosphohistidine-D-glucose phosphotransferase

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Results	in table
2	Activating Compound
2382	AA Sequence
7	Cloned(Commentary)
1	Crystallization (Commentary)
14	Expression
5	General Information
7	IC50 Value
18	Inhibitors
7	Ki Value [mM]
11	KM Value [mM]
19	Localization
1	Metals/Ions
6	Molecular Weight [Da]
49	Natural Substrates/ Products (Substrates)
257	Organism
4	Pathway
8	Posttranslational Modification
14	Protein Variants
6	Purification (Commentary)
1	Reaction
51	Reference
2	Specific Activity [micromol/min/mg]
66	Substrates and Products (Substrate)
10	Subunits
149	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 2.7.1.199 - protein-Npi-phosphohistidine-D-glucose phosphotransferase

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SYSTEMATIC NAME

IUBMB Comments

protein-Npi-phospho-L-histidine:D-glucose Npi-phosphotransferase

This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it. The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9 (phosphoenolpyruvate---protein phosphotransferase). Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency. The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.