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2.7.1.200: protein-Npi-phosphohistidine-galactitol phosphotransferase

This is an abbreviated version!
For detailed information about protein-Npi-phosphohistidine-galactitol phosphotransferase, go to the full flat file.

Word Map on EC 2.7.1.200

Reaction

[protein]-Npi-phospho-L-histidine
+
galactitol[side 1]
=
[protein]-L-histidine
+
galactitol 1-phosphate[side 2]

Synonyms

EC 2.7.1.69, EIIGat, ElIgat, galactitol phosphotransferase system, galactitol PTS permease, galactitol-specific enzyme II, galactitol-specific phosphoenolpyruvate-dependent phosphotransferase system, galactitol-specific transporter, gatA, GatA/GatB/GatC, gatABC, GatB, IIAGat/IIBGat/IICGat, IIBgat, IIGat

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.200 protein-Npi-phosphohistidine-galactitol phosphotransferase

Systematic Name

Systematic Name on EC 2.7.1.200 - protein-Npi-phosphohistidine-galactitol phosphotransferase

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SYSTEMATIC NAME
IUBMB Comments
protein-Npi-phospho-L-histidine:galactitol Npi-phosphotransferase
This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it. The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9 (phosphoenolpyruvate---protein phosphotransferase). Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency. The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.