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2.7.1.B26: aminoglycoside 3'-phosphotransferase

This is an abbreviated version!
For detailed information about aminoglycoside 3'-phosphotransferase, go to the full flat file.

Word Map on EC 2.7.1.B26

Reaction

GTP
+
gentamicin JI-20A
=
GDP
+
gentamicin JI-20A 3'-phosphate

Synonyms

aminoglycoside 3'-phosphotransferase VIII, APH(3'), APH-3'-IIIa, Aph3, APHVIII, biosynthetic aminoglycoside 3'-phosphotransferase, GnTI

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.B26 aminoglycoside 3'-phosphotransferase

Engineering

Engineering on EC 2.7.1.B26 - aminoglycoside 3'-phosphotransferase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
H123A
mutation has minimal effects on phosphorylation of several aminoglycosides
H188A
mutation has minimal effects on phosphorylation of several aminoglycosides
H78A
mutation has minimal effects on phosphorylation of several aminoglycosides
H82A
mutation has minimal effects on phosphorylation of several aminoglycosides