2.7.2.11: glutamate 5-kinase

This is an abbreviated version!
For detailed information about glutamate 5-kinase, go to the full flat file.

Reaction

Synonyms

ATP-L-glutamate 5-phosphotransferase, ATP:gamma-L-glutamate phosphotransferase, G5K, gamma-GK, gamma-glutamate kinase, gamma-glutamyl kinase, gamma-glutamylphosphate kinase, GK, GKA, glutamate kinase, glutamate-5-kinase, GPK, kinase (phosphorylating), glutamate, kinase, glutamate (phosphorylating), PRO1, proB, scGK

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.2 Phosphotransferases with a carboxy group as acceptor

                2.7.2.11 glutamate 5-kinase

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Results	in table
6	Activating Compound
34385	AA Sequence
6	Application
1	CAS Registry Number
16	Cloned(Commentary)
2	Cofactor
2	Crystallization (Commentary)
11	General Information
40	IC50 Value
53	Inhibitors
2	kcat/KM [mM/s]
15	Ki Value [mM]
20	KM Value [mM]
1	Localization
12	Metals/Ions
12	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
38	Organism
12	Pathway
52	PDB ID
6	pH Optimum
2	pH Range
1	pH Stability
61	Protein Variants
15	Purification (Commentary)
1	Reaction
1	Reaction Type
34	Reference
8	Source Tissue
11	Specific Activity [micromol/min/mg]
2	Storage Stability
51	Substrates and Products (Substrate)
11	Subunits
34	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
2	Temperature Stability [°C]
2	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.7.2.11 - glutamate 5-kinase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

ATP + L-glutamate

ADP + L-glutamate 5-phosphate

11 entries

ATP + L-glutamate

ADP + L-glutamate 5-phosphate

Escherichia coli

-

the enzyme catalyzes the first step in the pathway from glutamate to proline

642200, 642201

-

-

?

ATP + L-glutamate

ADP + L-glutamate 5-phosphate

Escherichia coli

-

enzyme is involved in biosynthesis of proline

390311

-

-

?

ATP + L-glutamate

ADP + L-glutamate 5-phosphate

Escherichia coli

-

enzyme catalyzes the first step of proline biosynthesis

660594

-

-

?

ATP + L-glutamate

ADP + L-glutamate 5-phosphate

Escherichia coli CM 25

-

the enzyme catalyzes the first step in the pathway from glutamate to proline

642201

-

-

?

ATP + L-glutamate

ADP + L-glutamate 5-phosphate

Leishmania donovani

A0A0R6Y3I5

-

761064

-

-

?

ATP + L-glutamate

ADP + L-glutamate 5-phosphate

Mycobacterium tuberculosis

P9WHU9

-

760828

-

-

?

ATP + L-glutamate

ADP + L-glutamate 5-phosphate

Mycobacterium tuberculosis H37Rv

P9WHU9

-

760828

-

-

?

ATP + L-glutamate

ADP + L-glutamate 5-phosphate

Saccharomyces cerevisiae

P32264

-

738247, 738715, 761649

-

-

?

ATP + L-glutamate

ADP + L-glutamate 5-phosphate

Solanum lycopersicum

-

-

642208

-

-

?

ATP + L-glutamate

ADP + L-glutamate 5-phosphate

Triticum aestivum

-

enzyme GK 1 is the first enzyme of the proline biosynthetic pathway

642205

-

-

?

ATP + L-glutamate

ADP + L-glutamate 5-phosphate

Triticum aestivum

-

enzyme form GK1 is involved in biosynthesis of L-Pro, enzyme form GK 2 is involved in biosynthesis of glutamine and the function of enzyme form GK 3 has not been found

642204

-

-

?