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Literature summary for 2.5.1.43 extracted from

  • Klatte, M.; Schuler, M.; Wirtz, M.; Fink-Straube, C.; Hell, R.; Bauer, P.
    The analysis of Arabidopsis nicotianamine synthase mutants reveals functions for nicotianamine in seed iron loading and iron deficiency responses (2009), Plant Physiol., 150, 257-271.
    View publication on PubMedView publication on EuropePMC
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Protein Variants

Protein Variants Comment Organism
additional information breeding nas T-DNA insertion mutants leads to mutants without NAS activity (named nas4x-2, sterile, strongly chlorotic) and with reduced NAS activity especially during the reproductive phase (named nas4x-1, leaves, roots, and flowers with symptoms of iron deficiency) Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Arabidopsis thaliana
-
root
-
 Arabidopsis thaliana
-
root expression is very low Arabidopsis thaliana
-

Synonyms

Synonyms Comment Organism
NAS1 Arabidopsis thaliana contains four NAS genes Arabidopsis thaliana
NAS2 Arabidopsis thaliana contains four NAS genes Arabidopsis thaliana
NAS3 Arabidopsis thaliana contains four NAS genes Arabidopsis thaliana
NAS4 Arabidopsis thaliana contains four NAS genes Arabidopsis thaliana
nicotianamine synthase
-
 Arabidopsis thaliana

Expression

Organism Comment Expression
Arabidopsis thaliana iron deficiency significantly decreases expression of NAS3 in leaves down
Arabidopsis thaliana in leaves and roots, NAS4 were up-regulated 2- to 3fold by Ni treatment up
Arabidopsis thaliana in leaves, NAS3 is up-regulated 3fold by Ni treatment up
Arabidopsis thaliana in roots, NAS1 is up-regulated twice by Ni treatment up
Arabidopsis thaliana iron deficiency markedly increases expression of NAS4 in leaves up
Arabidopsis thaliana iron deficiency slightly increases expression of NAS2 in roots up

General Information

General Information Comment Organism
metabolism biosynthesis of nicotianamine, which chelates and transports micronutrient metal ions in plants Arabidopsis thaliana