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Literature summary for 2.7.1.78 extracted from
- Sensitive detection of polynucleotide kinase activity by paper-based fluorescence assay with lambda exonuclease assistance (2016), Anal. Chem., 88, 11358-11363 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| (NH4)2SO4 | strong inhibition | Tequatrovirus T4 |  |
| ADP | strong inhibition | Tequatrovirus T4 | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Tequatrovirus T4 | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 5'-CGAGGCTGCACT-BHQ2-3' | - |
Tequatrovirus T4 | ADP + 5'-phospho-CGAGGCTGCACT-BHQ2-3' | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PNK | - |
Tequatrovirus T4 |
| polynucleotide kinase | - |
Tequatrovirus T4 |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 1.5 | - |
at pH 7.8 and 37°C | Tequatrovirus T4 | ADP | |
| 12.6 | - |
at pH 7.8 and 37°C | Tequatrovirus T4 | (NH4)2SO4 | |
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Release 2023.1 (January 2023)
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