EC Number   |
Application |
Reference |
|---|
    2.7.1.32 | biotechnology |
enzyme based assay for choline content of feed |
641382 |
| 2.7.1.32 | diagnostics |
choline kinase alpha expression is a new prognostic factor that could be used to help identify patients with earlystage non-small-cell lung cancer who might be at high risk of recurrence, and to identify patients with favourable prognosis who could receive less aggressive treatment options or avoid adjuvant systemic treatment. |
688743 |
| 2.7.1.32 | diagnostics |
prognostic factor in human cancer |
687121 |
| 2.7.1.32 | drug development |
choline kinase is a promising target for development of inhibitors and inhibition of tumor growth |
758809 |
| 2.7.1.32 | drug development |
choline kinase is elevated in cancer cells and presents a novel target for increasing cell kill. Data support exploring transient Chk silencing as a broad-spectrum chemotherapeutic agent for cancer cells. |
685941 |
| 2.7.1.32 | drug development |
choline kinase is gaining importance as a potential target for anticancer therapy |
685954 |
| 2.7.1.32 | drug development |
target for therapy since its specific inhibitors display efficient antitumoral activity in vivo |
687121 |
| 2.7.1.32 | drug development |
targeting the parasite lipid metabolism and choline kinase for pharmacological action constitutes an effective way of dealing with the spreading of the disease and with conventional therapy-resistant strains |
759092 |
| 2.7.1.32 | medicine |
enzyme downregulation is a cancer-specific treatment |
739185 |
| 2.7.1.32 | medicine |
in intact lenses, choline and ethanolamine are phosphorylated independently, during galactosemic cataractogenesis choline and ethanolamine become competing substrates of a single enzyme |
641381 |
