EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
2.1.1.103 | 0.0008 |
- |
NSC-22225 |
at pH 8.6 and 37°C |
735175 |
2.1.1.103 | 0.0028 |
- |
7-(3,5-dibromo-4-hydroxyphenethylamino)quinoline-5,8-dione |
combination of isoforms PMT1/PMT2, 24°C, pH not specified in the publication |
758529 |
2.1.1.103 | 0.003 |
- |
N-[5-[(9,10-dimethoxy-4-oxo-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-2-yl)amino]pentyl]propanamide |
pH not specified in the publication, temperature not specified in the publication |
756293 |
2.1.1.103 | 0.005 |
- |
NSC-39225 |
at pH 8.6 and 37°C |
735175 |
2.1.1.103 | 0.0051 |
- |
NSC-641296 |
combination of isoforms PMT1/PMT2, 24°C, pH not specified in the publication |
758529 |
2.1.1.103 | 0.0059 |
- |
7-(3,5-dibromo-4-hydroxyphenethylamino)quinoline-5,8-dione |
isoform PMT1 alone, 24°C, pH not specified in the publication |
758529 |
2.1.1.103 | 0.0083 |
- |
NSC-641296 |
isoform PMT1 alone, 24°C, pH not specified in the publication |
758529 |
2.1.1.103 | 0.009 |
- |
(3S)-1-(4-hydroxyphenyl)-N-[(2S)-1-[[2-(1H-indol-3-yl)ethyl]amino]-1-oxopropan-2-yl]-5-oxopyrrolidine-3-carboxamide |
pH not specified in the publication, temperature not specified in the publication |
756293 |
2.1.1.103 | 0.0125 |
- |
miltefosine |
isozyme PMT2, in 0.1 M HEPES (pH 8.0), 2 mM Na2EDTA, 10% glycerol, at 25°C |
719978 |
2.1.1.103 | 0.013 |
- |
diphenhydramine |
isozyme PMT2, in 0.1 M HEPES (pH 8.0), 2 mM Na2EDTA, 10% glycerol, at 25°C |
719978 |