1.2.1.24: succinate-semialdehyde dehydrogenase (NAD+)
This is an abbreviated version!
For detailed information about succinate-semialdehyde dehydrogenase (NAD+), go to the full flat file.
Word Map on EC 1.2.1.24
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1.2.1.24
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aldhs
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gamma-hydroxybutyric
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ssadhd
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4-hydroxybutyric
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propionaldehyde
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trans-4-hydroxy-2-nonenal
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aldh4a1
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akr7a2
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ssadh-deficient
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medicine
- 1.2.1.24
-
aldhs
-
gamma-hydroxybutyric
-
ssadhd
-
4-hydroxybutyric
- propionaldehyde
- trans-4-hydroxy-2-nonenal
- aldh4a1
-
akr7a2
-
ssadh-deficient
- medicine
Reaction
Synonyms
aldehyde dehydrogenase 5a1, ALDH5A, ALDH5A1, alphaKGSA dehydrogenase, dehydrogenase, succinate semialdehyde, NAD(+)-dependent succinic semialdehyde dehydrogenase, SSADH, SSADH-I, SSADH/ALDH5A1, SSALDH, SSO1629, succinate semialdehyde dehydrogenase, succinate semialdehyde:NAD+ oxidoreductase, succinic semialdehyde dehydrogenase, succinyl semialdehyde dehydrogenase, YneI dehydrogenase
ECTree
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Cloned
Cloned on EC 1.2.1.24 - succinate-semialdehyde dehydrogenase (NAD+)
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expressed in Escherichia coli M15 cells
expression in Escherichia coli as His-tag fusion protein
expression of mutant enzymes is expressed after transfection of HEK293 cells
gene ALDH5A1 gene, located in the 6p22.3 region, genotyping, recombinant epression of wild-type and mutant enzymes in HEK-293 cells, quantitative RT-PCR expression analysis
gene ALDH5A1, screening and genotyping, DNA and amino acid sequence determination and analysis
into vectors pQE30 and into pMalc2x. Expression in Escherichia coli strains M15 and TB1
PCR product cloned into pCR2.1-Topo. Open reading frame ligated into vector QE30. Overexpressed in Escherichia coli M15. Subcloned into pMALc2x and expressed in Escherichia coli TB1
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into vectors pQE30 and into pMalc2x. Expression in Escherichia coli strains M15 and TB1