1.2.1.47: 4-trimethylammoniobutyraldehyde dehydrogenase

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For detailed information about 4-trimethylammoniobutyraldehyde dehydrogenase, go to the full flat file.

Reaction

Synonyms

4-N-trimethylaminobutyraldehyde dehydrogenase, 4-N-trimethylaminobutyraldehyde dehydrogenase II, 4-trimethylaminobutyraldehyde dehydrogenase, 4-trimethylammoniobutyraldehyde dehydrogenase, aldehyde dehydrogenase 9A1, Aldh9a1, carnitine biosynthesis enzyme, dehydrogenase, trimethylaminobutyraldehyde, gamma-trimethylaminobutyraldehyde dehydrogenase, TMABA dehydrogenase, TMABA-DH, TMABADH, TMABAL dehydrogenase, TMABaldehyde-DH II, TMABALDH

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.1 With NAD⁺ or NADP⁺ as acceptor

                1.2.1.47 4-trimethylammoniobutyraldehyde dehydrogenase

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Results	in table
1	Activating Compound
30	AA Sequence
1	Application
1	CAS Registry Number
5	Cloned(Commentary)
16	Cofactor
2	Crystallization (Commentary)
9	Disease/ Diagnostics
3	Expression
6	General Information
1	General Stability
44	Inhibitors
5	Ki Value [mM]
36	KM Value [mM]
8	Localization
1	Metals/Ions
9	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
19	Organism
5	Pathway
30	PDB ID
6	pH Optimum
1	pH Range
2	pH Stability
2	pI Value
7	Purification (Commentary)
1	Reaction
4	Reaction Type
18	Reference
54	Source Tissue
16	Specific Activity [micromol/min/mg]
3	Storage Stability
69	Substrates and Products (Substrate)
11	Subunits
36	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
3	Temperature Stability [°C]

Expression

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Expression on EC 1.2.1.47 - 4-trimethylammoniobutyraldehyde dehydrogenase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

detection of mRNA levels in foetuses, increase during postnatal life, expression is ontogenically regulated

Rattus norvegicus

Q9JLJ3

699966

PPARalpha regulates the expression of ALDH9A1 gene

Homo sapiens

P49189

762831

the enzyme gene is activated by peroxisome proliferator-activated receptor alpha directly and by WY-14,643 in the liver of wild type mice

Mus musculus

Q9JLJ2

724438