1.4.1.B2: L-erythro-3,5-diaminohexanoate dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about L-erythro-3,5-diaminohexanoate dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

3,5-DAHDH, Kdd

ECTree

     1 Oxidoreductases

         1.4 Acting on the CH-NH₂ group of donors

             1.4.1 With NAD⁺ or NADP⁺ as acceptor

                1.4.1.B2 L-erythro-3,5-diaminohexanoate dehydrogenase (NADP+)

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Results	in table
2	AA Sequence
2	Cloned(Commentary)
7	Cofactor
1	Crystallization (Commentary)
2	General Information
32	Inhibitors
12	Ki Value [mM]
14	KM Value [mM]
4	Metals/Ions
4	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
5	Organism
2	pH Optimum
3	pH Range
1	pH Stability
27	Protein Variants
2	Purification (Commentary)
1	Reaction
5	Reference
1	Specific Activity [micromol/min/mg]
3	Storage Stability
14	Substrates and Products (Substrate)
3	Subunits
2	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Temperature Stability [°C]

Natural Substrates Products

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Natural Substrates Products on EC 1.4.1.B2 - L-erythro-3,5-diaminohexanoate dehydrogenase (NADP+)

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

L-erythro-3,5-diaminohexanoate + H2O + NAD+

5-amino-3-oxohexanoate + NH3 + NADH + H+

Acetoanaerobium sticklandii

-

either NAD+ or NADP+ serve as coenzyme. Double-reciprocal plots of activity versus pyridine nucleotide concentration are biphasic. The Km values for NADP+ are lower but a higher Vmax is observed with NAD+

696177

-

-

?

L-erythro-3,5-diaminohexanoate + H2O + NADP+

(S)-5-amino-3-oxohexanoate + NH3 + NADPH + H+

2 entries

L-erythro-3,5-diaminohexanoate + H2O + NADP+

5-amino-3-oxohexanoate + NH3 + NADPH + H+

Acetoanaerobium sticklandii

-

either NAD+ or NADP+ serve as coenzyme. Double-reciprocal plots of activity versus pyridine nucleotide concentration are biphasic. The Km values for NADP+ are lower but a higher Vmax is observed with NAD+

696177

-

-

?

L-erythro-3,5-diaminohexanoate + H2O + NADP+

(S)-5-amino-3-oxohexanoate + NH3 + NADPH + H+

Candidatus Cloacimonas acidaminovorans

-

-

741483

-

-

?

L-erythro-3,5-diaminohexanoate + H2O + NADP+

(S)-5-amino-3-oxohexanoate + NH3 + NADPH + H+

unidentified

A1X0G6

-

698741

-

-

?