2.1.1.100: protein-S-isoprenylcysteine O-methyltransferase

This is an abbreviated version!
For detailed information about protein-S-isoprenylcysteine O-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.100

2.1.1.100

n-acetyl-s-farnesyl-l-cysteine

cysmethynil

medicine

a-factor

aax

carboxylmethylation

ste24p

n-acetyl-s-geranylgeranyl-l-cysteine

ras-driven

biotechnology

analysis

drug development

pharmacology

Reaction

protein C-terminal S-farnesyl-L-cysteine

protein C-terminal S-farnesyl-L-cysteine methyl ester

Synonyms

EC 2.1.1.24, farnesyl cysteine C-terminal methyltransferase, farnesyl-protein carboxymethyltransferase, farnesylated protein C-terminal O-methyltransferase, Icmt, isoprenylated protein methyltransferase, isoprenylcysteine carboxyl methyltransferase, isoprenylcysteine carboxylmethyltransferase, isoprenylcysteine carboxylmethyltransferase Ste14p, isoprenylcysteine methylesterase, methyltransferase, protein C-terminal farnesylcysteine O-, prenylated protein methyltransferase, protein S-farnesylcysteine C-terminal methyltransferase, S-farnesylcysteine methyltransferase, STE14A, STE14B, Ste14p

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.100 protein-S-isoprenylcysteine O-methyltransferase

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Results	in table
6	Activating Compound
5180	AA Sequence
16	Application
1	CAS Registry Number
17	Cloned(Commentary)
3	Cofactor
115	Disease/ Diagnostics
2	Expression
13	General Information
2	General Stability
217	IC50 Value
371	Inhibitors
46	Ki Value [mM]
74	KM Value [mM]
33	Localization
2	Metals/Ions
12	Molecular Weight [Da]
21	Natural Substrates/ Products (Substrates)
75	Organism
2	Pathway
2	PDB ID
5	pH Optimum
2	pH Range
1	pH Stability
33	Protein Variants
7	Purification (Commentary)
3	Reaction
1	Reaction Type
74	Reference
61	Source Tissue
3	Specific Activity [micromol/min/mg]
1	Storage Stability
121	Substrates and Products (Substrate)
9	Subunits
88	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 2.1.1.100 - protein-S-isoprenylcysteine O-methyltransferase

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180000

Oryctolagus cuniculus

gel filtration

485027

23000

Saccharomyces cerevisiae

2 * 23000, untagged enzyme, SDS-PAGE

719860

24000

Saccharomyces cerevisiae

radiation inactivation

485029

26000

Saccharomyces cerevisiae

x * 26000, SDS-PAGE

733252

28301

Trypanosoma brucei

x * 28301, deduced from nucleotide sequence

485045

30000

Bos taurus

gel filtration, photoaffinity labelling

485040

33000

Homo sapiens

x * 33000, SDS-PAGE

733252

35000

Saccharomyces cerevisiae

2 * 35000, His-tagged enzyme, SDS-PAGE

719860

36000

Saccharomyces cerevisiae

x * 36000, His-tagged enzyme, SDS-PAGE

734533

86000

2 entries

98000

Rattus norvegicus

radiation inactivation

485029