2.1.1.100: protein-S-isoprenylcysteine O-methyltransferase

This is an abbreviated version!
For detailed information about protein-S-isoprenylcysteine O-methyltransferase, go to the full flat file.

Reaction

Synonyms

EC 2.1.1.24, farnesyl cysteine C-terminal methyltransferase, farnesyl-protein carboxymethyltransferase, farnesylated protein C-terminal O-methyltransferase, Icmt, isoprenylated protein methyltransferase, isoprenylcysteine carboxyl methyltransferase, isoprenylcysteine carboxylmethyltransferase, isoprenylcysteine carboxylmethyltransferase Ste14p, isoprenylcysteine methylesterase, methyltransferase, protein C-terminal farnesylcysteine O-, prenylated protein methyltransferase, protein S-farnesylcysteine C-terminal methyltransferase, S-farnesylcysteine methyltransferase, STE14A, STE14B, Ste14p

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.100 protein-S-isoprenylcysteine O-methyltransferase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
6	Activating Compound
5180	AA Sequence
16	Application
1	CAS Registry Number
17	Cloned(Commentary)
3	Cofactor
115	Disease/ Diagnostics
2	Expression
13	General Information
2	General Stability
217	IC50 Value
371	Inhibitors
46	Ki Value [mM]
74	KM Value [mM]
33	Localization
2	Metals/Ions
12	Molecular Weight [Da]
21	Natural Substrates/ Products (Substrates)
75	Organism
2	Pathway
2	PDB ID
5	pH Optimum
2	pH Range
1	pH Stability
33	Protein Variants
7	Purification (Commentary)
3	Reaction
1	Reaction Type
74	Reference
61	Source Tissue
3	Specific Activity [micromol/min/mg]
1	Storage Stability
121	Substrates and Products (Substrate)
9	Subunits
88	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Turnover Number [1/s]

General Stability

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

General Stability on EC 2.1.1.100 - protein-S-isoprenylcysteine O-methyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to General Stability Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

complete loss of activity after exposure to detergent e.g. CHAPS, octyl-beta-glucoside and sodium deoxycholate, activity can be reconstituted by removal of the detergent in the presence of phospholipid

Homo sapiens

-

485032

the membrane-associated activity is highly stable even upon repeated freeze-thaw cycles

Saccharomyces cerevisiae

-

659510