2.1.1.198: 16S rRNA (cytidine1402-2'-O)-methyltransferase

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For detailed information about 16S rRNA (cytidine1402-2'-O)-methyltransferase, go to the full flat file.

Reaction

Synonyms

RsmI, YraL

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.198 16S rRNA (cytidine1402-2'-O)-methyltransferase

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Results	in table
38027	AA Sequence
2	Cloned(Commentary)
2	Crystallization (Commentary)
5	General Information
1	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
38	Organism
3	PDB ID
4	Protein Variants
2	Purification (Commentary)
1	Reaction
5	Reference
5	Substrates and Products (Substrate)
1	Subunits
7	Synonyms
1	Systematic Name

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Engineering on EC 2.1.1.198 - 16S rRNA (cytidine1402-2'-O)-methyltransferase

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PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

A124L

Escherichia coli

P67087

complete loss of binding affinity, mutation abolishes the side chain-mediating H-bond with SAM

758139

D100K

Escherichia coli

P67087

complete loss of binding affinity, mutation abolishes the side chain-mediating H-bond with SAM

758139

F144A

Escherichia coli

P67087

binding affinities and entropy are moderately affected

758139

Y169A

Escherichia coli

P67087

binding affinity and enthalpy/entropy are very similar to that of the wild-type

758139