2.1.1.229: tRNA (carboxymethyluridine34-5-O)-methyltransferase
This is an abbreviated version!
For detailed information about tRNA (carboxymethyluridine34-5-O)-methyltransferase, go to the full flat file.
Word Map on EC 2.1.1.229
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2.1.1.229
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wobble
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methyltransferases
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5-methoxycarbonylmethyluridine
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ribonucleotide
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anticodon
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gene-specific
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trnagluuuc
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translationally
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medicine
- 2.1.1.229
-
wobble
- methyltransferases
-
5-methoxycarbonylmethyluridine
- ribonucleotide
-
anticodon
-
gene-specific
- trnagluuuc
-
translationally
- medicine
Reaction
Synonyms
ABH8, ALKBH8, CmoA, MnmC, Trm9, Trm9-Trm112, Trm9p, TrmC, tRNA methyltransferase 9, YfcK, YML014w
ECTree
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Activating Compound
Activating Compound on EC 2.1.1.229 - tRNA (carboxymethyluridine34-5-O)-methyltransferase
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TRM112
interaction of ALKBH8 with a small accessory protein, TRM112, is required to form a functional tRNA methyltransferase
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Trm112 p
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the presence of Trm112p dramatically improves the methyltransferase activity of Trm9p in vitro
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Trm112p
when produced in Escherichia coli, Trm112p forms a complex with Trm9p, which renders the latter soluble. This recombinant complex catalyzes the formation of mcm5U34 (5-methoxycarbonylmethyluridine) on tRNA in vitro but not mcm5s2U34 (5-methoxycarbonylmethyl-2-thiouridine)
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