2.1.1.251: methylated-thiol-coenzyme M methyltransferase

This is an abbreviated version!
For detailed information about methylated-thiol-coenzyme M methyltransferase, go to the full flat file.

Reaction

a [methyl-Co(III) methylated-thiol-specific corrinoid protein]

a [Co(I) methylated-thiol-specific corrinoid protein]

Synonyms

480-kDa CoM methylase, CoM methylase, DMS:CoM methyltransferase, methylthiol:coenzyme M methyltransferase, methylthiol:CoM methyltransferase, methyltransferase II, MMPA:CoM methyltransferase, MtsA

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.251 methylated-thiol-coenzyme M methyltransferase

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Results	in table
3	Activating Compound
20	AA Sequence
1	CAS Registry Number
2	Cloned(Commentary)
2	Cofactor
13	General Information
1	Inhibitors
5	KM Value [mM]
3	Metals/Ions
5	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
10	Organism
5	Pathway
2	pH Optimum
2	Purification (Commentary)
4	Reaction
6	Reference
1	Renatured (Commentary)
6	Source Tissue
1	Specific Activity [micromol/min/mg]
32	Substrates and Products (Substrate)
1	Subunits
25	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]

Reference

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Reference on EC 2.1.1.251 - methylated-thiol-coenzyme M methyltransferase

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717563

Kr�er, M.; Haumann, M.; Meyer-Klaucke, W.; Thauer, R.; Dau, H.

The role of zinc in the methylation of the coenzyme M thiol group in methanol:coenzyme M methyltransferase from Methanosarcina barkeri: new insights from X-ray absorption spectroscopy

Eur. J. Biochem.

269

2117-2123

2002

Methanosarcina barkeri, Methanosarcina barkeri Fusaro, DSM 804

11985589

717716

Paul, L.; Krzycki, J.

Sequence and transcript analysis of a novel Methanosarcina barkeri methyltransferase II homolog and its associated corrinoid protein homologous to methionine synthase

J. Bacteriol.

178

6599-6607

1996

Methanosarcina barkeri (Q48924)

8932317

717763

Tallant, T.; Paul, L.; Krzycki, J.

The MtsA subunit of the methylthiol:coenzyme M methyltransferase of Methanosarcina barkeri catalyses both half-reactions of corrinoid-dependent dimethylsulfide: coenzyme M methyl transfer

J. Biol. Chem.

276

4485-4493

2001

Methanosarcina barkeri

11073950

727732

Tallant, T.C.; Krzycki, J.A.

Methylthiol:coenzyme M methyltransferase from Methanosarcina barkeri, an enzyme of methanogenesis from dimethylsulfide and methylmercaptopropionate

J. Bacteriol.

179

6902-6911

1997

Methanosarcina barkeri, Methanosarcina barkeri DSM 800

9371433