2.1.1.281: phenylpyruvate C3-methyltransferase

This is an abbreviated version!
For detailed information about phenylpyruvate C3-methyltransferase, go to the full flat file.

Reaction

Synonyms

C-MT, ELQ87_35210, MppJ, MT SgvM, phenylpyruvate Cbeta-methyltransferase, phenylpyruvate methyltransferase, S-adenosylmethionine-dependent methyltransferase, SgvM

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.281 phenylpyruvate C3-methyltransferase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
16	AA Sequence
1	Application
3	Cloned(Commentary)
1	Cofactor
1	Crystallization (Commentary)
5	General Information
2	kcat/KM [mM/s]
2	KM Value [mM]
1	Metals/Ions
2	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
6	Organism
1	pH Optimum
10	Protein Variants
2	Purification (Commentary)
3	Reaction
5	Reference
18	Substrates and Products (Substrate)
2	Subunits
13	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
2	Turnover Number [1/s]

General Information

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

General Information on EC 2.1.1.281 - phenylpyruvate C3-methyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to General Information Search

evolution

2 entries

physiological function

Streptomyces griseoviridis

A0A3Q9KTF8

S-adenosylmethionine-dependent methyltransferases (MTs) play a decisive role in the biosynthesis of natural products and in epigenetic processes. MTs catalyze the methylation of heteroatoms and even of carbon atoms, which, in many cases, is a challenging reaction in conventional synthesis. C-MTs are often highly substrate-specific. SgvM from Streptomyces griseoviridis features an extended substrate scope with respect to the nucleophile as well as the electrophile. It catalyze the transfer of the electrophilic methyl group of SAM to the C3 position of 4-methyl-2-oxovalerate (alpha-ketoleucine)

755790

additional information

2 entries