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2.1.1.4: acetylserotonin O-methyltransferase

This is an abbreviated version!
For detailed information about acetylserotonin O-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.4

Reaction

S-adenosyl-L-methionine
+
N-acetylserotonin
=
S-adenosyl-L-homocysteine
 +
Melatonin

Synonyms

acetylserotonin methyltransferase, ASMT, ASMT1, ASMT2, COMT, HIOMT, hydroxindole-O-methyltransferase, hydroxyindole methyltransferase, hydroxyindole O-methyltransferase, hydroxyindole-O-methyl transferase, hydroxyindole-O-methyltransferase, MANES_17G050500, methyltransferase, acetylserotonin, N-acetylserotonin methyltransferase, N-acetylserotonin methyltransferase1, N-acetylserotonin O-methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.4 acetylserotonin O-methyltransferase

Specific Activity

Specific Activity on EC 2.1.1.4 - acetylserotonin O-methyltransferase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0000007
purified recombinant enzyme, pH 7.8, 37°C
0.000007
-
purified GST-tagged recombinant enzyme, pH not specified in the publication, 30°C
0.000013
-
purified nontagged recombinant enzyme, pH not specified in the publication, 30°C
0.00003
-
purified nontagged recombinant enzyme, pH not specified in the publication, 30°C, at 10 mM substrate N-acetylserotonin concentration
additional information