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2.1.1.44: L-histidine Nalpha-methyltransferase

This is an abbreviated version!
For detailed information about L-histidine Nalpha-methyltransferase, go to the full flat file.

Reaction

3 S-adenosyl-L-methionine +

L-histidine
= 3 S-adenosyl-L-homocysteine +
hercynine

Synonyms

dimethylhistidine methyltransferase, EgtD, histidine-alpha-N-methyltransferase, methyltransferase, histidine Nalpha-

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.44 L-histidine Nalpha-methyltransferase

KCat KM Value

KCat KM Value on EC 2.1.1.44 - L-histidine Nalpha-methyltransferase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0019 - 5.3
L-histidine
0.0024 - 0.1
L-phenylalanine
0.002 - 5.5
L-tryptophan
0.0011 - 0.017
L-tyrosine
17
Nalpha,Nalpha-dimethyl-L-histidine
wild-type, pH 8.0, 26°C
13
Nalpha-methyl-L-histidine
wild-type, pH 8.0, 26°C