2.3.1.15: glycerol-3-phosphate 1-O-acyltransferase
This is an abbreviated version!
For detailed information about glycerol-3-phosphate 1-O-acyltransferase, go to the full flat file.
Word Map on EC 2.3.1.15
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2.3.1.15
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gpats
-
triacylglycerols
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phospholipid
-
phosphatidic
-
glycerolipids
-
acyl-coas
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triglyceride
-
diacylglycerol
-
adipose
-
lysophosphatidic
-
peroxisome
-
lipogenesis
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lipogenic
-
adipocytes
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palmitate
-
sterol
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phosphatidylcholine
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palmitoyl-coa
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phosphohydrolase
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glycerophospholipids
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carnitine
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steatosis
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esterification
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stearoyl-coa
-
dihydroxyacetone
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1-acylglycerol-3-phosphate
-
cutin
-
srebp-1
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phosphatidylglycerol
-
palmitoyltransferase
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oleoyl-coa
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acyl-acyl
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cytidylyltransferase
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squash
-
desaturase-1
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monoacylglycerol
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protein-1c
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acaca
-
suberin
-
synthesis
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nutrition
-
cholinephosphotransferase
-
insig1
-
lipins
-
medicine
-
energy production
-
biotechnology
- 2.3.1.15
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gpats
- triacylglycerols
- phospholipid
-
phosphatidic
- glycerolipids
- acyl-coas
- triglyceride
- diacylglycerol
- adipose
-
lysophosphatidic
- peroxisome
-
lipogenesis
-
lipogenic
- adipocytes
- palmitate
- sterol
- phosphatidylcholine
- palmitoyl-coa
-
phosphohydrolase
- glycerophospholipids
- carnitine
- steatosis
- esterification
- stearoyl-coa
- dihydroxyacetone
-
1-acylglycerol-3-phosphate
- cutin
- srebp-1
- phosphatidylglycerol
- palmitoyltransferase
- oleoyl-coa
-
acyl-acyl
- cytidylyltransferase
- squash
-
desaturase-1
- monoacylglycerol
- protein-1c
- acaca
- suberin
- synthesis
- nutrition
-
cholinephosphotransferase
-
insig1
-
lipins
- medicine
- energy production
- biotechnology
Reaction
Synonyms
1-acyl-sn-glycerol-3-phosphate acyltransferase, 3-glycerophosphate acyltransferase, ACP:sn-glycerol-3-phosphate acyltransferase, acyl-CoA:glycerol-3-phosphate acyltransferase 1, acyl-CoA:sn-glycerol-3-phosphate O-acyltransferase, acyl-[acyl carrier protein]:sn-1-glycerol-3-phosphate acyltransferase, acyltransferase, glycerol phosphate, Ad-GPAT1, AGPAT, AGPAT10, AGPAT6, AGPAT8, AGPAT9, alpha-glycerophosphate acyltransferase, AT1G02390, AT1G06520, AT3G11430, AT4G00400, AT4G01950, AT5G06090, AT5G60620, AtGPAT1, AtGPAT2, AtGPAT3, AtGPAT5, AtGPAT7, AtGPAT8, AtGPAT9, cancer-testicular antigen, chloroplast glycerol-3-phosphate acyltransferase, CrGAPTcl, ER-associated GPAT, G3P acyltransferase, GAT, Gat1, GAT1p, GAT2p, glycerol 3-phosphate acyltransferase, glycerol phosphate acyltransferase, glycerol phosphate transacylase, glycerol-3-P acyltransferase 1, glycerol-3-phosphate acyltransferase, glycerol-3-phosphate acyltransferase 1, glycerol-3-phosphate acyltransferase 2, glycerol-3-phosphate acyltransferase 3, glycerol-3-phosphate acyltransferase 4, glycerol-3-phosphate acyltransferase 9, glycerol-3-phosphate acyltransferase-1, glycerol-3-phosphate acyltransferase-like protein 1, glycerol-3-phosphate O-acyltransferase, glycerol-3-phosphate-1 acyltransferase, glycerol-sn-3-phosphate acyltransferase 1, glycerophosphate acyltransferase, glycerophosphate transacylase, GPAM, GPAT, GPAT-1, GPAT-4, GPAT-9, GPAT1, GPAT2, GPAT3, GPAT3/AGPAT10, GPAT4, GPAT5, GPAT6, GPAT7, GPAT8, GPAT9, gpt1, Gpt2, LeGPAT, LiGPAT, LPAAT-theta, LPAAT-zeta, mGPAT, microsomal GPAT3, microsomal GPAT3/AGPAT10, microsomal GPAT4, mitochondrial glycerol-3-phosphate acyltransferase, mitochondrial GPAT1, mitochondrial GPAT2, More, MS33, mtGPAT, mtGPAT1, mtGPAT2, OsGPAT3, PHATRDRAFT_42446, PHYPADRAFT_137573, PLAT2, PlsB, PlsB1, Ppa GPAT9, PpGPAT9, PtGPAT, Rv1551, Rv1551 acyltransferase, SA1, Sn-glycerol 3-phosphate acyltransferase, sn-glycerol-3-phosphate acyltransferase, SsGPAT, TbGAT, water-soluble plastidial glycerol-3-phosphate acyltransferase, xGPAT1, xGPAT1-v1, xGPAT1-v2
ECTree
2.3.1.15 glycerol-3-phosphate 1-O-acyltransferaseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 2.3.1.15 - glycerol-3-phosphate 1-O-acyltransferase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
acyl-CoA + sn-glycerol 3-phosphate
CoA + 2-acyl-sn-glycerol 3-phosphate
reaction of EC 2.3.1.198, glycerol-3-phosphate 2-O-acyltransferase
-
-
?
acyl-[acyl-carrier protein] + sn-glycerol 3-phosphate
acyl-carrier protein + 1-acyl-sn-glycerol 3-phosphate
-
acyl-[acyl-carrier-protein] is probably the physiological substrate
-
?
dicarboxylic acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-dicarboxylic acyl-sn-glycerol 3-phosphate
-
-
-
?
dicarboxylic acyl-CoA + sn-glycerol 3-phosphate
CoA + 2-dicarboxylic acyl-sn-glycerol 3-phosphate
reaction of EC 2.3.1.198, glycerol-3-phosphate 2-O-acyltransferase
-
-
?
docosahexaenoyl-CoA + sn-glycerol 3-phosphate
CoA + 1-docosahexaenoyl-sn-glycerol 3-phosphate
oleoyl-CoA + sn-glycerol 3-phosphate
CoA + 1-oleoyl-sn-glycerol 3-phosphate
-
high activity
-
-
?
omega-hydroxy acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-omega-hydroxy acyl-sn-glycerol 3-phosphate
-
-
-
?
omega-hydroxy-acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-omega-hydroxy-acyl-sn-glycerol 3-phosphate
-
-
-
?
omega-hydroxy-acyl-CoA + sn-glycerol 3-phosphate
CoA + 2-omega-hydroxy-acyl-sn-glycerol 3-phosphate
reaction of EC 2.3.1.198, glycerol-3-phosphate 2-O-acyltransferase
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
first committed step in biosynthesis of fatty acid biosynthesis, the enzyme is responsible for incorporation of saturated and unsaturated fatty-acyl chains into chloroplast membranes
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
initial step in membrane phospholipid biosynthesis
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
key enzyme in de novo triacylglycerol synthesis
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
i.e. lysophosphatidic acid
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
enzyme catalyzes the initial and rate-limiting step of glycerolipid synthesis with long-chain acyl-CoAs
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
key enzyme in de novo triacylglycerol synthesis
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
acylation of sn-glycerol 3-phosphate with longchain acyl-CoA
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
initial reaction of glycolipid biosynthesis
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
initial reaction of phosphoglycerol biosynthesis
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
the enzyme catalyzes the first and committed step in the synthesis of glycerophospholipids and TAG from sn-glycerol-3-phosphate
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
the enzyme catalyzes the first and committed step in the synthesis of glycerophospholipids and triacylglycerol from sn-glycerol-3-phosphate
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
initial reaction of glycolipid biosynthesis
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
first committed step in biosynthesis of fatty acid biosynthesis, the enzyme is responsible for incorporation of saturated and unsaturated fatty-acyl chains into chloroplast membranes
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
initial reaction of cocoa butter biosynthesis
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + 1-acyl-sn-glycerol 3-phosphate
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + lysophosphatidic acid
-
-
-
-
?
acyl-CoA + sn-glycerol 3-phosphate
CoA + lysophosphatidic acid
-
-
-
-
?
docosahexaenoyl-CoA + sn-glycerol 3-phosphate
CoA + 1-docosahexaenoyl-sn-glycerol 3-phosphate
-
-
-
?
docosahexaenoyl-CoA + sn-glycerol 3-phosphate
CoA + 1-docosahexaenoyl-sn-glycerol 3-phosphate
-
-
-
?
palmitoyl-CoA + sn-glycerol 3-phosphate
CoA + 1-palmitoyl-sn-glycerol 3-phosphate
-
-
-
?
palmitoyl-CoA + sn-glycerol 3-phosphate
CoA + 1-palmitoyl-sn-glycerol 3-phosphate
-
-
-
-
?
palmitoyl-CoA + sn-glycerol 3-phosphate
CoA + 1-palmitoyl-sn-glycerol 3-phosphate
-
-
-
-
?
additional information
?
-
plastidial lysophosphatidic acid acyltransferase (CrLPAAT1, EC 2.3.1.51) is found to be interacting with the water-soluble plastidial glycerol-3-phosphate acyltransferase (CrGAPTcl) via its two transmembrane domains in vitro. The interaction between CrLPAAT1 and CrGPATcl can be negatively regulated by both the acyl-CoAs and lysophosphatidic acid in a dosage-dependent manner. Recombinant CrLPAAT1(wild-type) and CrLPAAT1(mut) and the control Trx-S-His6-tag protein in concentration gradients are incubated with the immobilized CrGPATcl, respectively. These recombinant proteins except CrGPATcl have the S tag and can be detected by anti-S tag antibody. Simultaneously, anti-CrGPATcl antibody is used for interaction detection in Western blotting. Kinetics of the CrLPAAT1-CrGPATcl interaction, overview. The stability of CrLPAAT1-CrGPATcl complex is inversely proportional to the concentrations of acyl donors used in the assays, and it is most sensitive to the high-concentration of C18:1 (n9)-CoA among various acyl donors
-
-
-
additional information
?
-
-
the content of cis-unsaturated fatty acids in the plastidial phosphatidyl glycerol determines the degree of sensitivity to chilling, the higher it is the more tolerant are the plants to chilling, squash is chilling-sensitive, overview
-
-
?
additional information
?
-
GPAT1 preferentially catalyzes saturated fatty acids (FAs) (palmitate or C16:0) and selectively transfers acyl-CoA to the sn-1 position of glycerol 3-phosphate. Subsequently, lysophosphatidic acid, phosphatidic acid, and diacylglycerol are produced in the glycerophospholipid pathway
-
-
-
additional information
?
-
GPAT1 preferentially catalyzes saturated fatty acids (FAs) (palmitate or C16:0) and selectively transfers acyl-CoA to the sn-1 position of glycerol 3-phosphate. Subsequently, lysophosphatidic acid, phosphatidic acid, and diacylglycerol are produced in the glycerophospholipid pathway
-
-
-
additional information
?
-
GPAT1 preferentially catalyzes saturated fatty acids (FAs) (palmitate or C16:0) and selectively transfers acyl-CoA to the sn-1 position of glycerol 3-phosphate. Subsequently, lysophosphatidic acid, phosphatidic acid, and diacylglycerol are produced in the glycerophospholipid pathway
-
-
-
additional information
?
-
-
enzyme important for the synthesis of triacylglycerol but not essential for virulence
-
-
?
additional information
?
-
-
mtGPAT1 is essential for normal acyl-CoA metabolism: The absence of hepatic mtGPAT1 results in the partitioning of fatty acids away from triacylglycerol synthesis and toward oxidation and ketogenesis
-
-
?
additional information
?
-
GPAT1 preferentially catalyzes saturated fatty acids (FAs) (palmitate or C16:0) and selectively transfers acyl-CoA to the sn-1 position of glycerol 3-phosphate. Subsequently, lysophosphatidic acid, phosphatidic acid, and diacylglycerol are produced in the glycerophospholipid pathway
-
-
-
additional information
?
-
GPAT1 preferentially catalyzes saturated fatty acids (FAs) (palmitate or C16:0) and selectively transfers acyl-CoA to the sn-1 position of glycerol 3-phosphate. Subsequently, lysophosphatidic acid, phosphatidic acid, and diacylglycerol are produced in the glycerophospholipid pathway
-
-
-
additional information
?
-
GPAT1 preferentially catalyzes saturated fatty acids (FAs) (palmitate or C16:0) and selectively transfers acyl-CoA to the sn-1 position of glycerol 3-phosphate. Subsequently, lysophosphatidic acid, phosphatidic acid, and diacylglycerol are produced in the glycerophospholipid pathway
-
-
-
additional information
?
-
GPAT1 preferentially catalyzes saturated fatty acids (FAs) (palmitate or C16:0) and selectively transfers acyl-CoA to the sn-1 position of glycerol 3-phosphate. Subsequently, lysophosphatidic acid, phosphatidic acid, and diacylglycerol are produced in the glycerophospholipid pathway
-
-
-
additional information
?
-
-
aging and acyl-CoA binding protein alter mitochondrial enzyme activity
-
-
?
additional information
?
-
-
the content of cis-unsaturated fatty acids in the plastidial phosphatidyl glycerol determines the degree of sensitivity to chilling, the higher it is the more tolerant are the plants to chilling, spinach is chilling-insensitive, while squash is chilling-sensitive, overview
-
-
?
