2.3.1.193: tRNAMet cytidine acetyltransferase
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For detailed information about tRNAMet cytidine acetyltransferase, go to the full flat file.
Reaction
Synonyms
tmcA, ypfI
ECTree
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Systematic Name
Systematic Name on EC 2.3.1.193 - tRNAMet cytidine acetyltransferase
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acetyl-CoA:[elongator tRNAMet]-cytidine34 N4-acetyltransferase (ATP-hydrolysing)
The enzyme acetylates the wobble base cytidine34 of the CAU anticodon of elongation-specific tRNAMet. Escherichia coli TmcA strictly discriminates elongator tRNAMet from tRNAIle, which is structurally similar and has the same anticodon loop, mainly by recognizing the C27-G43 pair in the anticodon stem. The enzyme can use GTP in place of ATP for formation of N4-acetylcytidine [1].